An autoimmune genetic disorder with an unknown pattern of inheritance that primarily affects the digestive tract. It is caused by intolerance to dietary gluten. Consumption of gluten protein triggers an immune response which damages small intestinal villi and prevents adequate absorption of nutrients. Clinical signs include abdominal cramping, diarrhea or constipation and weight loss. If untreated, the clinical course may progress to malnutrition, anemia, osteoporosis and an increased risk of intestinal malignancies. However, the prognosis is favorable with successful avoidance of gluten in the diet. [ ]

Synonyms: idiopathic steatorrhea Celiac syndrome Celiac rickets (disorder) Coeliac sprue CS - Celiac sprue Gluten enteropathy Gluten-Induced Enteropathy Celiac disease NOS Celiac disease (disorder) Gluten-Sensitive Enteropathy Coeliac disease Gluten Enteropathies GSE - Gluten-sensitive enteropathy Sprue, Nontropical Gluten Sensitive Enteropathy Non Tropical Sprue Gluten-Sensitive Enteropathies Coeliac disease [Ambiguous] Coeliac disease NOS Sprue, Celiac celiac disease Disease, Celiac CS - Coeliac sprue CELIAC DIS Non-tropical sprue CD - Celiac disease Gluten-responsive sprue celiac sprue Enteropathy, Gluten Celiac disease NOS (disorder) Celiac rickets Sprue Celiac Sprue gluten-induced enteropathy Gluten-induced enteropathy syndrome CD - Coeliac disease Coeliac syndrome Coeliac rickets coeliac disease Enteropathies, Gluten Nontropical Sprue non tropical sprue Steatorrhoea - idiopathic Idiopathic steatorrhoea Wheat-sensitive enteropathy Idiopathic steatorrhea Enteropathy, Gluten-Sensitive Enteropathies, Gluten-Sensitive

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Tomasz Adamusiak
James Malone