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melanoma

^ http://www.ebi.ac.uk/efo/EFO_0000756


A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)

A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.

Synonyms: MM - Malignant melanoma, Melanoma, Malignant, Malignant melanoma, no ICD-O subtype, Melanomas, Malignant melanoma, NOS, [M]Malignant melanoma NOS (morphologic abnormality), Malignant melanoma, no ICD-O subtype (morphologic abnormality), Malignant Melanoma, [M]Malignant melanoma NOS, Naevocarcinoma, Malignant melanoma (morphologic abnormality), malignant melanoma NOS (morphologic abnormality), Malignant melanoma, morphology (morphologic abnormality), malignant melanoma (disorder), Melanosarcoma, Malignant Melanomas, Melanomas, Malignant, Melanoma, NOS

Term info

OMIM definition citation

OMIM:155755, OMIM:155600

SNOMEDCT definition citation

SNOMEDCT:372244006, SNOMEDCT:2092003

bioportal provenance

MM - Malignant melanoma[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], Malignant melanoma (disorder)[accessedResource: SNOMEDCT:372244006][accessDate: 05-04-2011], malignant melanoma NOS (morphologic abnormality)[accessedResource: DOID:1909][accessDate: 05-04-2011], Melanomas[accessedResource: MSH:D008545][accessDate: 05-04-2011], Malignant melanoma[accessedResource: SNOMEDCT:372244006][accessDate: 05-04-2011], malignant melanoma, morphology (morphologic abnormality)[accessedResource: DOID:1909][accessDate: 05-04-2011], Malignant melanoma, no ICD-O subtype[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], Melanosarcoma[accessedResource: SNOMEDCT:372244006][accessDate: 05-04-2011], [M]Malignant melanoma NOS (morphologic abnormality)[accessedResource: SNOMEDCT:269503007][accessDate: 05-04-2011], Malignant melanoma, NOS[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], Malignant Melanomas[accessedResource: MSH:D008545][accessDate: 05-04-2011], Melanoma, Malignant[accessedResource: MSH:D008545][accessDate: 05-04-2011], Malignant melanoma, no ICD-O subtype (morphologic abnormality)[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], [M]Malignant melanoma NOS[accessedResource: SNOMEDCT:269503007][accessDate: 05-04-2011], Malignant melanoma (morphologic abnormality)[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], A malignant neoplasm derived from cells that are capable of forming melanin, which may occur in the skin of any part of the body, in the eye, or, rarely, in the mucous membranes of the genitalia, anus, oral cavity, or other sites. It occurs mostly in adults and may originate de novo or from a pigmented nevus or malignant lentigo. Melanomas frequently metastasize widely, and the regional lymph nodes, liver, lungs, and brain are likely to be involved. The incidence of malignant skin melanomas is rising rapidly in all parts of the world. (Stedman, 25th ed; from Rook et al., Textbook of Dermatology, 4th ed, p2445)[accessedResource: MSH:D008545][accessDate: 05-04-2011], A malignant, usually aggressive tumor composed of atypical, neoplastic melanocytes. Most often, melanomas arise in the skin (cutaneous melanomas) and include the following histologic subtypes: superficial spreading melanoma, nodular melanoma, acral lentiginous melanoma, and lentigo maligna melanoma. Cutaneous melanomas may arise from acquired or congenital melanocytic or dysplastic nevi. Melanomas may also arise in other anatomic sites including the gastrointestinal system, eye, urinary tract, and reproductive system. Melanomas frequently metastasize to lymph nodes, liver, lungs, and brain.[accessedResource: NCIt:C3224][accessDate: 05-04-2011], Naevocarcinoma[accessedResource: DOID:1909][accessDate: 05-04-2011], Melanoma, NOS[accessedResource: SNOMEDCT:2092003][accessDate: 05-04-2011], Melanomas, Malignant[accessedResource: MSH:D008545][accessDate: 05-04-2011]

gwas trait

true

term editor

Tomasz Adamusiak, James Malone