A chronic disorder, possibly autoimmune, marked by excessive production of collagen which results in hardening and thickening of body tissues. The two types of systemic scleroderma, limited cutaneous and diffuse cutaneous are classified with focus on the extent of affected skin. A relationship exists between the extent of skin area affected and degree of internal organ/system involvement. Systemic scleroderma can manifest itself in pulmonary fibrosis, Raynaud's syndrome, digestive system telangiectasias, renal hypertension and/or pulmonary hypertension. [ NCIT : C72070 ]

Synonyms:

SSc, diffuse sclerosis

Thibierge-Weissenbach syndrome

Progressive systemic sclerosis

SSc

systemic sclerosis

Scleroderma

Systemic sclerosis

Systemic sclerosis (disorder)

Sclerosis, Systemic

PSS (progressive systemic sclerosis)

systemic scleroderma

progressive systemic sclerosis

Scleroderma syndrome

systemic Scleroderma

SS - Systemic sclerosis

Scleroderma (& [systemic sclerosis])

Scleroderma, diffuse

Scleroderma, Systemic

PSS - Progressive systemic sclerosis

diffuse Scleroderma

Scleroderma, systemic

diffuse sclerosis

This is just here as a test because I lose it

Term information

database cross reference
  • MedDRA:10042953 (Orphanet:90291/e)
  • ICD9:710.1 (MONDO:i2s)
  • MESH:D012595 (MONDO:equivalentTo)
  • ICD10:M34
  • NCIT:C72070 (MONDO:equivalentTo)
  • GARD:0009748 (MONDO:equivalentTo)
  • Orphanet:90291 (MONDO:equivalentTo)
  • UMLS:CN206012 (MONDO:equivalentTo)
  • MedDRA:10036814
  • NCIt:C72070
  • SNOMEDCT:444133002
  • DOID:418 (MONDO:equivalentTo)
  • MONDO:0005100
  • SCTID:89155008 (MONDO:equivalentTo)
  • SNOMEDCT:89155008
  • MedDRA:10078638
  • MeSH:D012595
Subsets

ordo_disease

closeMatch
  • http://identifiers.org/meddra/10042953
exactMatch
  • http://purl.obolibrary.org/obo/DOID_418
  • http://purl.obolibrary.org/obo/Orphanet_90291
  • http://purl.obolibrary.org/obo/NCIT_C72070
  • http://identifiers.org/mesh/D012595
  • http://identifiers.org/snomedct/89155008
  • http://linkedlifedata.com/resource/umls/id/CN206012
gwas trait
  • true
has broad synonym
  • Scleroderma
id
  • EFO:0000717
term editor
  • James Malone
  • Gautier Koscielny