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neuroblastoma

^ http://www.ebi.ac.uk/efo/EFO_0000621


A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH).

A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)

Synonyms: [M]Neuroblastoma NOS (morphologic abnormality), (neuroblastoma NOS) or (sympathicoblastoma), NB - Neuroblastoma, neuroblastoma (Schwannian Stroma-Poor), Neuroblastoma, NOS, Neuroblastomas, neuroblastoma (morphologic abnormality), Sympathicoblastoma, [M]Neuroblastoma NOS, neuroblastoma NOS (morphologic abnormality), Central neuroblastoma

Term info

NIFSTD definition citation

NIFSTD:birnlex_12631

OMIM definition citation

OMIM:613014, OMIM:613013, OMIM:256700

SNOMEDCT definition citation

SNOMEDCT:87364003, SNOMEDCT:432328008

bioportal provenance

(neuroblastoma NOS) or (sympathicoblastoma)[accessedResource: DOID:769][accessDate: 05-04-2011], Central neuroblastoma[accessedResource: SNOMEDCT:87364003][accessDate: 05-04-2011], neuroblastoma NOS (morphologic abnormality)[accessedResource: DOID:769][accessDate: 05-04-2011], [M]Neuroblastoma NOS[accessedResource: SNOMEDCT:269507008][accessDate: 05-04-2011], neuroblastoma (Schwannian Stroma-Poor)[accessedResource: DOID:769][accessDate: 05-04-2011], A neuroblastic tumor characterized by the presence of neuroblastic cells, the absence of ganglion cells, and the absence of a prominent Schwannian stroma formation.[accessedResource: NCIt:C3270][accessDate: 05-04-2011], [M]Neuroblastoma NOS (morphologic abnormality)[accessedResource: SNOMEDCT:269507008][accessDate: 05-04-2011], Neuroblastomas[accessedResource: MSH:D009447][accessDate: 05-04-2011], Neuroblastoma, NOS[accessedResource: SNOMEDCT:87364003][accessDate: 05-04-2011], NB - Neuroblastoma[accessedResource: SNOMEDCT:87364003][accessDate: 05-04-2011], A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome. (From DeVita et al., Cancer: Principles and Practice of Oncology, 5th ed, pp2099-2101; Curr Opin Oncol 1998 Jan;10(1):43-51)[accessedResource: MSH:D009447][accessDate: 05-04-2011], A common neoplasm of early childhood arising from neural crest cells in the sympathetic nervous system, and characterized by diverse clinical behavior, ranging from spontaneous remission to rapid metastatic progression and death. This tumor is the most common intraabdominal malignancy of childhood, but it may also arise from thorax, neck, or rarely occur in the central nervous system. Histologic features include uniform round cells with hyperchromatic nuclei arranged in nests and separated by fibrovascular septa. Neuroblastomas may be associated with the opsoclonus-myoclonus syndrome (MeSH).[accessedResource: NIFSTD:birnlex_12631][accessDate: 05-04-2011], neuroblastoma (morphologic abnormality)[accessedResource: DOID:769][accessDate: 05-04-2011], Sympathicoblastoma[accessedResource: SNOMEDCT:87364003][accessDate: 05-04-2011]

gwas trait

true

term editor

Tomasz Adamusiak, James Malone