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leukemia

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A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.

A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)

A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.

Synonyms: Leukaemia, NOS, Leukemias, General, Leukemia NOS (disorder), Blood (Leukemia), chronic leukemia, Leukemia, morphology (morphologic abnormality), Leukemias, Leukemia, disease, Leukaemia, disease, chronic leukemia, disease (disorder), Leukaemia

Term info

ICD9 definition citation

ICD9:208, ICD9:207, ICD9:208.8, ICD9:207.8, ICD9:208.9

SNOMEDCT definition citation

SNOMEDCT:93143009, SNOMEDCT:87163000

bioportal provenance

LEUK NOS W/O ACHV RMSN[accessedResource: ICD9:208.90][accessDate: 05-04-2011], Blood (Leukemia)[accessedResource: NCIt:C3161][accessDate: 05-04-2011], [X]Other leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011], Other specified leukemia[accessedResource: ICD9:207][accessDate: 05-04-2011], Leukaemia, disease[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], [M]Leukemia NOS[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011], Leukaemia morphology[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Leukaemia, NOS[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], [X]Other leukaemia of unspecified cell type[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011], Leukaemia NOS[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011], Subacute leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Leukemia, NOS, without mention of remission[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], OTH SPF LEUK W REMSION[accessedResource: ICD9:207.81][accessDate: 05-04-2011], [M]Leukemias unspecified[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011], A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years.[accessedResource: NCIt:C3161][accessDate: 05-04-2011], Other specified leukemia NOS[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011], [X]Other specified leukemias[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011], OTH LEUK UNS CL W RMSON[accessedResource: ICD9:208.81][accessDate: 05-04-2011], Leukemia morphology[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Aleukemic leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], OTH LEUK W/O ACHV RMSN[accessedResource: ICD9:207.80][accessDate: 05-04-2011], [M]Leukaemia NOS[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011], Leukaemia[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], [M]Leukaemia unspecified, NOS[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011], Leukaemia, no ICD-O subtype[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], [M]leukemia unspecified, NOS (morphologic abnormality)[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011], [M]Leukaemias unspecified[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011], [X]Other specified leukaemias[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011], Other leukaemia of unspecified cell type[accessedResource: SNOMEDCT:188766004][accessDate: 05-04-2011], Subacute leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Other specified leukaemia NOS[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011], Leukemia, morphology (morphologic abnormality)[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], [X]Other leukemia of unspecified cell type[accessedResource: SNOMEDCT:190162005][accessDate: 05-04-2011], Other leukemia of unspecified cell type in remission[accessedResource: ICD9:208.81][accessDate: 05-04-2011], Other leukemia of unspecified cell type without mention of having achieved remission[accessedResource: ICD9:208.80][accessDate: 05-04-2011], Other specified leukaemia[accessedResource: SNOMEDCT:188751002][accessDate: 05-04-2011], [M]Leukemia unspecified, NOS[accessedResource: SNOMEDCT:190029004][accessDate: 05-04-2011], Other leukemia of unspecified cell type[accessedResource: ICD9:208.8][accessDate: 05-04-2011], Leukemias, General[accessedResource: NCIt:C3161][accessDate: 05-04-2011], Leukemia, disease[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], Leukemia, NOS[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Leukemia, no ICD-O subtype[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Leukemia, disease (disorder)[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], Chronic leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Other specified leukemia without mention of having achieved remission[accessedResource: ICD9:207.80][accessDate: 05-04-2011], Leukaemia, NOS, without mention of remission[accessedResource: SNOMEDCT:93143009][accessDate: 05-04-2011], Unspecified leukemia without mention of having achieved remission[accessedResource: ICD9:208.90][accessDate: 05-04-2011], [M]leukemia NOS (morphologic abnormality)[accessedResource: SNOMEDCT:190025005][accessDate: 05-04-2011], Leukemia NOS (disorder)[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011], Leukemia NOS[accessedResource: SNOMEDCT:188767008][accessDate: 05-04-2011], [M]leukemias unspecified (morphologic abnormality)[accessedResource: SNOMEDCT:190024009][accessDate: 05-04-2011], A progressive, malignant disease of the blood-forming organs, characterized by distorted proliferation and development of leukocytes and their precursors in the blood and bone marrow. Leukemias were originally termed acute or chronic based on life expectancy but now are classified according to cellular maturity. Acute leukemias consist of predominately immature cells; chronic leukemias are composed of more mature cells. (From The Merck Manual, 2006)[accessedResource: MSH:D007938][accessDate: 05-04-2011], Unspecified leukemia[accessedResource: ICD9:208.9][accessDate: 05-04-2011], Leukaemia of unspecified cell type[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011], A cancer that affects the blood or bone marrow characterized by an abnormal proliferation of blood cells.[accessedResource: DOID:1240][accessDate: 05-04-2011], Other specified leukemia in remission[accessedResource: ICD9:207.81][accessDate: 05-04-2011], Leukemia, no ICD-O subtype (morphologic abnormality)[accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Other specified leukemia NOS (disorder)[accessedResource: SNOMEDCT:188761009][accessDate: 05-04-2011], Aleukaemic leukaemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Leukemias[accessedResource: MSH:D007938][accessDate: 05-04-2011], Other specified leukemia (disorder)[accessedResource: SNOMEDCT:188751002][accessDate: 05-04-2011], OT LEU UN CL WO ACH RMSN[accessedResource: ICD9:208.80][accessDate: 05-04-2011], Chronic leukemia [obs][accessedResource: SNOMEDCT:87163000][accessDate: 05-04-2011], Other leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:188766004][accessDate: 05-04-2011], [X]Other specified leukemias (disorder)[accessedResource: SNOMEDCT:190161003][accessDate: 05-04-2011], Leukemia of unspecified cell type[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011], Leukemia of unspecified cell type (disorder)[accessedResource: SNOMEDCT:188762002][accessDate: 05-04-2011]

term editor

James Malone, Tomasz Adamusiak

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