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diffuse large B-cell lymphoma

^ http://www.ebi.ac.uk/efo/EFO_0000403


A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg type, and ALK-positive large B-cell lymphoma.

Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.

Synonyms: Lymphoma, Large B-Cell, Diffuse, Large-Cell Lymphomas, Diffuse, Lymphoma, Large-Cell, Diffuse, DLBCL, Histiocytic Lymphoma, Lymphoma, Histiocytic, Lymphomas, Diffuse Histiocytic, Histiocytic Lymphoma, Diffuse, Large-Cell Lymphomas, Lymphoma, Diffuse Large Cell, Lymphoma, Diffuse Large-Cell, LYMPHOMA LARGE DIFFUSE, DIFFUSE LARGE LYMPHOMA, Lymphomas, Diffuse Large-Cell, Large Cell Lymphoma, Diffuse, LARGE LYMPHOMA DIFFUSE, Lymphoma, Large Cell, Diffuse, Lymphomas, Large-Cell, Lymphoma, Large-Cell, Diffuse Histiocytic Lymphomas, Large Cell Lymphoma, Diffuse Large Cell Lymphoma, Lymphomas, Histiocytic, Histiocytic Lymphomas, Diffuse, Histiocytic Lymphomas, Lymphoma, Histiocytic, Diffuse, LARGE LYMPHOMA, LYMPHOMA LARGE, Diffuse Histiocytic Lymphoma, Diffuse, Large B-Cell, Lymphoma, Diffuse Large-Cell Lymphomas, Lymphoma, Diffuse Histiocytic, large B-cell lymphoma, Large-Cell Lymphoma, Diffuse, LYMPHOMA DIFFUSE LARGE, Large Lymphoid Lymphoma, Diffuse, Lymphoma, Large Cell, Diffuse Large-Cell Lymphoma, Large-Cell Lymphoma, Lymphoma, Large Lymphoid, Diffuse

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bioportal provenance

Lymphomas, Diffuse Large-Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Diffuse Large-Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], DIFFUSE LARGE LYMPHOMA[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large-Cell Lymphomas, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], LYMPHOMA LARGE DIFFUSE[accessedResource: MSH:D016403][accessDate: 05-04-2011], LARGE LYMPHOMA DIFFUSE[accessedResource: MSH:D016403][accessDate: 05-04-2011], Malignant lymphoma composed of large B lymphoid cells whose nuclear size can exceed normal macrophage nuclei, or more than twice the size of a normal lymphocyte. The pattern is predominantly diffuse. Most of these lymphomas represent the malignant counterpart of B-lymphocytes at midstage in the process of differentiation.[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse Large-Cell Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Histiocytic Lymphomas[accessedResource: MSH:D016403][accessDate: 05-04-2011], LYMPHOMA DIFFUSE LARGE[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large-Cell, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], LARGE LYMPHOMA[accessedResource: MSH:D016403][accessDate: 05-04-2011], DLBCL[accessedResource: NCIt:C8851][accessDate: 05-04-2011], Large Cell Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large-Cell Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], A non-Hodgkin lymphoma characterized by a diffuse proliferation of predominantly large neoplastic B lymphocytes. It is the most frequently seen type of non-Hodgkin lymphoma, representing 30%-40% of the cases. Morphologic variants include centroblastic lymphoma, immunoblastic lymphoma, and anaplastic lymphoma. Subtypes/entities include T-cell/histiocyte rich large B-cell lymphoma, primary diffuse large B-cell lymphoma of the central nervous system, plasmablastic lymphoma, primary cutaneous diffuse large B-cell lymphoma, leg type, and ALK-positive large B-cell lymphoma.[accessedResource: NCIt:C8851][accessDate: 05-04-2011], Lymphoma, Diffuse Large Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large-Cell Lymphoma, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large Cell Lymphoma, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse, Large B-Cell, Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse Large Cell Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large Lymphoid, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large Cell, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Histiocytic Lymphomas, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], LYMPHOMA LARGE[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphomas, Diffuse Histiocytic[accessedResource: MSH:D016403][accessDate: 05-04-2011], Histiocytic Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse Histiocytic Lymphoma[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse Histiocytic Lymphomas[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Histiocytic, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphomas, Histiocytic[accessedResource: MSH:D016403][accessDate: 05-04-2011], Histiocytic Lymphoma, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large-Cell Lymphomas[accessedResource: MSH:D016403][accessDate: 05-04-2011], Large Lymphoid Lymphoma, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large B-Cell, Diffuse[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphomas, Large-Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large-Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], Diffuse Large-Cell Lymphomas[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Histiocytic[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Large Cell[accessedResource: MSH:D016403][accessDate: 05-04-2011], Lymphoma, Diffuse Histiocytic[accessedResource: MSH:D016403][accessDate: 05-04-2011]

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term editor

Tomasz Adamusiak

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