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chronic myelogenous leukemia

^ http://www.ebi.ac.uk/efo/EFO_0000339


Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.

Synonyms: Leukemias, Ph1-Positive Myelogenous, Myelocytic Leukemias, Chronic, Myeloid Leukemia, Philadelphia Positive, Leukemia, Myeloid, Philadelphia Positive, Chronic Myelocytic Leukemia, Myelogenous Leukemias, Ph1-Positive, Chronic Granulocytic Leukemia, Leukemia, Myelogenous, Chronic, Leukemia, Chronic Granulocytic, Ph1-Positive Myelogenous Leukemia, Myeloid leukemia, chronic, Leukemias, Chronic Myelocytic, Philadelphia-Positive Myeloid Leukemias, chronic myeloid leukemia, Myelogenous Leukemia, Ph1 Positive, Myelogenous Leukemia, Ph1-Positive, Myelogenous Leukemias, Chronic, Granulocytic Leukemias, Chronic, CML, Ph1-Positive Myeloid Leukemias, Leukemia, Myelogenous, Chronic, BCR-ABL Positive, Leukemia, Myelocytic, Chronic, Leukemia, Myeloid, Chronic-Phase, chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality), Leukemia, Myelogenous, Ph1-Positive, Leukemias, Chronic Granulocytic, Leukemia, Myeloid, Philadelphia-Positive, Myeloid Leukemia, Philadelphia-Positive, Leukemias, Chronic Myeloid, Philadelphia-Positive Myeloid Leukemia, Leukemia, Chronic Myelogenous, Leukemia, Myeloid, Chronic, Chronic Myelocytic Leukemias, Myeloid Leukemia, Ph1-Positive, Myeloid Leukemias, Ph1-Positive, Chronic Granulocytic Leukemias, Leukemia, Myeloid, Ph1 Positive, Leukemia, Philadelphia-Positive Myeloid, Chronic Myeloid Leukemias, Leukemia, Myelogenous, Ph1 Positive, Myelogenous Leukemia, Chronic, LEUKEMIA PHILA POS, Chronic Myelogenous Leukemias, Myeloid Leukemia, Ph1 Positive, Leukemias, Chronic Myelogenous, Leukemia, Myeloid, Ph1-Positive, Leukemia, Ph1-Positive Myelogenous, Leukemias, Ph1-Positive Myeloid, Myeloid Leukemias, Chronic, chronic myeloid leukemia in remission (disorder), Leukemia, Chronic Myeloid, Leukemia, Granulocytic, Chronic, Leukemias, Philadelphia-Positive Myeloid, chronic myeloid leukemia NOS (disorder), Granulocytic Leukemia, Chronic, chronic myeloid leukemia without mention of remission, Myelocytic Leukemia, Chronic, CML in Remission, Myeloid Leukemias, Philadelphia-Positive, Ph1-Positive Myelogenous Leukemias, chronic myeloid leukemia in remission, CML - chronic Myelogenous Leukemia, chronic myeloid leukaemia, Ph1-Positive Myeloid Leukemia, chronic myeloid leukemia, disease (disorder), Leukemia, Chronic Myelocytic, Philadelphia-Positive Myelogenous Leukemia, Leukemia, Ph1-Positive Myeloid

Term info

MSH definition citation

MSH:D015464, MSH:D015466

SNOMEDCT definition citation

SNOMEDCT:92818009, SNOMEDCT:63364005, SNOMEDCT:92817004

bioportal provenance

Leukemia, Myelogenous, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Ph1-Positive Myelogenous[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myeloid, Philadelphia Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Ph1-Positive Myelogenous Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], CML - chronic Myelogenous Leukemia[accessedResource: DOID:8552][accessDate: 05-04-2011], LEUKEMIA PHILA POS[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukemia without mention of remission[accessedResource: DOID:8552][accessDate: 05-04-2011], Myelogenous Leukemias, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukaemia[accessedResource: DOID:8552][accessDate: 05-04-2011], Leukemia, Myelogenous, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myeloid, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukemia in remission[accessedResource: DOID:8552][accessDate: 05-04-2011], Leukemia, Chronic Granulocytic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Ph1-Positive Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Granulocytic Leukemia, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Myeloid Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelocytic Leukemias, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Chronic Myelocytic[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukemia in remission (disorder)[accessedResource: DOID:8552][accessDate: 05-04-2011], Leukemia, Myelogenous, Ph1 Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelogenous Leukemia, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Chronic Myelogenous[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Myelocytic Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Granulocytic, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Philadelphia-Positive Myeloid Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukemia NOS (disorder)[accessedResource: DOID:8552][accessDate: 05-04-2011], Leukemias, Chronic Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemia, Ph1 Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Chronic Granulocytic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Chronic Myelocytic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Chronic Myelogenous[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Myeloid Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myelocytic, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Myelogenous Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Ph1-Positive Myelogenous[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemia, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myelogenous, Chronic, BCR-ABL Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemias, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Granulocytic Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelogenous Leukemia, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myeloid leukemia, disease (disorder)[accessedResource: DOID:8552][accessDate: 05-04-2011], Granulocytic Leukemias, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Ph1-Positive Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myeloid, Ph1 Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemias, Philadelphia-Positive Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemia, Philadelphia Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelogenous Leukemias, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemia, Philadelphia-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], CML[accessedResource: DOID:8552][accessDate: 05-04-2011], CML in Remission[accessedResource: DOID:8552][accessDate: 05-04-2011], Ph1-Positive Myeloid Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Granulocytic Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Myeloid, Philadelphia-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Philadelphia-Positive Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelogenous Leukemia, Ph1 Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], chronic myelogenous leukemia, no ICD-O subtype (morphologic abnormality)[accessedResource: DOID:8552][accessDate: 05-04-2011], Leukemia, Myeloid, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Ph1-Positive Myelogenous Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Philadelphia-Positive Myeloid Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Chronic Myelocytic Leukemias[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myelocytic Leukemia, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Leukemia, Chronic Myeloid[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemia, Chronic[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemias, Philadelphia-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Ph1-Positive Myeloid Leukemia[accessedResource: MSH:D015464][accessDate: 05-04-2011], Myeloid Leukemias, Ph1-Positive[accessedResource: MSH:D015464][accessDate: 05-04-2011], Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.[accessedResource: MSH:D015464][accessDate: 05-04-2011]

gwas trait

true

term editor

James Malone, Tomasz Adamusiak