acute lymphoblastic leukemia
http://www.ebi.ac.uk/efo/EFO_0000220
A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.
A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.
Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia.
Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the precursor B lymphoblastic leukemia and precursor T lymphoblastic leukemia.
When the disease process is confined to a mass lesion with no or minimal evidence of blood and less than 25% marrow involvement, the diagnosis is lymphoblastic lymphoma; with blood and greater than 25% marrow involvement, ALL is the appropriate term.
Synonyms: ALL, Acute lymphatic leukemia, L2 type, Precursor B Cell Lymphoblastic Leukemia, ALL - Acute lymphoblastic leukaemia, Pre B ALL, Acute lymphoid leukaemia, [M]Acute lymphoid leukaemia, Leukemia, Lymphoblastic, Leukemia, Lymphoblastic, Acute, Leukemia, Acute Lymphoblastic, Acute Lymphocytic Leukemias, Leukemia, Acute Lymphocytic, Lymphoblastic Leukemia, Acute, Acute lymphoid leukaemia, disease, Leukemia, Acute Lymphoid, Acute lymphatic leukaemia, FAB L2, Lymphoid Leukemia, Acute, L1 Lymphocytic Leukemia, Precursor cell lymphoblastic leukemia (morphologic abnormality), Pre B Cell Leukemia, Pre-B ALL, Acute lymphoid leukaemia, L2 type, Leukemia, L1 Lymphocytic, Acute lymphatic leukaemia, L2 type, Acute lymphoid leukemia, disease (disorder), Lymphoblastic Leukemia, Acute, Adult, Acute lymphoid leukemia without mention of having achieved remission, Lymphoblastic leukemia, L2 type, Acute lymphoblastic leukemia, precursor-cell type, Acute Lymphogenous Leukemia, Leukemia, Pre B Cell, [M]Acute lymphoid leukemia, Acute lymphoblastic leukaemia-lymphoma, Leukemia, Lymphoid, Acute, Leukemia, Lymphoblastic, Acute, L2, Leukemia, L2 Lymphocytic, Leukemia, Lymphoblastic, Acute, L1, Acute lymphoblastic leukaemia, Childhood ALL, ALL, Childhood, Leukemia, Pre-B-Cell, Acute lymphoblastic leukaemia, precursor-cell type, Acute lymphoblastic leukaemia, L2 type, Lymphocytic Leukemia, Acute, Pre-B-Cell Leukemia, Precursor B-Cell Lymphoblastic Leukemia, Lymphocytic Leukemia, L2, Pre B-ALL, Precursor cell lymphoblastic leukemia, no ICD-O subtype (morphologic abnormality), Lymphocytic Leukemia, L1, Lymphoblastic Leukemia, Acute, Childhood, Acute lymphoid leukemia, Precursor cell lymphoblastic leukaemia, Precursor B Cell Lymphoblastic Leukemia Lymphoma, ACT LYM LEUK W/O RMSION, Precursor Lymphoblastic Leukemia, Acute lymphoblastic leukemia, L2 type, Acute lymphoid leukemia, disease, Acute lymphoid leukemia, L2 type, Leukemia, Lymphoblastic, Acute, Philadelphia-Positive, Acute lymphocytic leukaemia, L2 type, Precursor B-Cell Lymphoblastic Lymphoma, Pre-B-Cell Leukemias, ALL - Acute lymphoblastic leukemia, Precursor cell lymphoblastic leukaemia, not phenotyped, Acute lymphatic leukemia, Acute lymphoblastic leukemia-lymphoma, Leukemia, Lymphocytic, Acute, L1, Leukemia, Lymphocytic, Acute, L2, Lymphoblastic Leukemia, Acute, L1, Lymphoblastic Leukemia, Acute, L2, Precursor B-Cell Lymphoblastic Leukemia-Lymphoma, Acute Lymphocytic Leukaemia, Precursor cell lymphoblastic leukemia, not phenotyped, Leukemia, Lymphocytic, Acute, Precursor Cell Lymphoblastic Leukemia-Lymphoma, Precursor Cell Lymphoblastic Leukemia Lymphoma, Precursor B Cell Lymphoblastic Lymphoma, Precursor cell lymphoblastic leukemia, ALL - Acute Lymphocytic Leukemia, L2 Lymphocytic Leukemia, Acute lymphocytic leukemia, L2 type, Acute lymphoid leukemia without mention of remission, [M]Acute lymphoid leukemia (morphologic abnormality), Lymphoblastic leukaemia, L2 type, Acute Lymphocytic Leukemia, AC LYM LEUK WO ACHV RMSN, Leukemias, Pre-B-Cell
Term info
DOID:9952
ICD9:204.0
MSH:D054198
NCIt:C3167
OMIM:613065
SNOMEDCT:128807009, SNOMEDCT:900000000000452009, SNOMEDCT:128822004, SNOMEDCT:128823009, SNOMEDCT:91857003
Precursor B Cell Lymphoblastic Lymphoma[accessedResource: MSH:D015452][accessDate: 05-04-2011], Leukemia, Lymphocytic, Acute[accessedResource: MSH:D054198][accessDate: 05-04-2011], Pre-B-Cell Leukemia[accessedResource: MSH:D015452][accessDate: 05-04-2011], Acute lymphoid leukemia, disease[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], Acute lymphoblastic leukemia-lymphoma[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemia, Acute Lymphoid[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor cell lymphoblastic leukemia, no ICD-O subtype (morphologic abnormality)[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute lymphatic leukemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], ALL[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Acute lymphatic leukaemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemias, Pre-B-Cell[accessedResource: MSH:D015452][accessDate: 05-04-2011], Pre B ALL[accessedResource: MSH:D015452][accessDate: 05-04-2011], Acute lymphoblastic leukemia, precursor-cell type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Precursor cell lymphoblastic leukemia, not phenotyped[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Lymphocytic Leukemia, L1[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Lymphoblastic, Acute, Philadelphia-Positive[accessedResource: MSH:D054198][accessDate: 05-04-2011], When the disease process is confined to a mass lesion with no or minimal evidence of blood and less than 25% marrow involvement, the diagnosis is lymphoblastic lymphoma; with blood and greater than 25% marrow involvement, ALL is the appropriate term.[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor Lymphoblastic Leukemia[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Lymphoblastic leukaemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Precursor B Cell Lymphoblastic Leukemia[accessedResource: MSH:D015452][accessDate: 05-04-2011], Lymphoblastic Leukemia, Acute[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Pre B Cell[accessedResource: MSH:D015452][accessDate: 05-04-2011], Acute lymphoid leukemia without mention of having achieved remission[accessedResource: ICD9:204.00][accessDate: 05-04-2011], Lymphoblastic leukemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Lymphoblastic Lymphoma[accessedResource: MSH:D054198][accessDate: 05-04-2011], AC LYM LEUK WO ACHV RMSN[accessedResource: ICD9:204.00][accessDate: 05-04-2011], Acute lymphoblastic leukaemia, precursor-cell type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Precursor B-Cell Lymphoblastic Leukemia[accessedResource: MSH:D015452][accessDate: 05-04-2011], Childhood ALL[accessedResource: MSH:D054198][accessDate: 05-04-2011], A neoplasm characterized by abnormalities of the lymphoid cell precursors leading to excessive lymphoblasts in the marrow and other organs. It is the most common cancer in children and accounts for the vast majority of all childhood leukemias.[accessedResource: MSH:D054198][accessDate: 05-04-2011], [M]Acute lymphoid leukemia (morphologic abnormality)[accessedResource: SNOMEDCT:190034000][accessDate: 05-04-2011], Acute lymphoid leukemia without mention of remission[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], L2 Lymphocytic Leukemia[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphoblastic leukaemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Lymphoblastic Leukemia, Acute, Adult[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphoid leukaemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Lymphoblastic leukemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute lymphoid leukemia, disease (disorder)[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], Lymphoblastic Leukemia, Acute, L2[accessedResource: MSH:D054198][accessDate: 05-04-2011], Lymphomas, Lymphoblastic[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor B-Cell Lymphoblastic Lymphoma[accessedResource: MSH:D015452][accessDate: 05-04-2011], ALL - Acute lymphoblastic leukemia[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], Lymphoblastic Leukemia, Acute, L1[accessedResource: MSH:D054198][accessDate: 05-04-2011], Lymphocytic Leukemia, L2[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute Lymphocytic Leukemia[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Lymphoblastic leukaemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Pre B-ALL[accessedResource: MSH:D015452][accessDate: 05-04-2011], Acute lymphocytic leukemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute Lymphocytic Leukaemia[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Leukemia, Lymphoblastic, Acute, L2[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Acute Lymphoblastic[accessedResource: MSH:D054198][accessDate: 05-04-2011], Lymphoblastic Leukemia, Acute, Childhood[accessedResource: MSH:D054198][accessDate: 05-04-2011], Pre-B ALL[accessedResource: MSH:D015452][accessDate: 05-04-2011], Leukemia, Lymphoblastic, Acute[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphocytic leukaemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemia with an acute onset, characterized by the presence of lymphoblasts in the bone marrow and the peripheral blood. It includes the acute B lymphoblastic leukemia and acute T lymphoblastic leukemia.[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Leukemia, Lymphocytic, Acute, L2[accessedResource: MSH:D054198][accessDate: 05-04-2011], L1 Lymphocytic Leukemia[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Lymphoid, Acute[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Acute Lymphocytic[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor Cell Lymphoblastic Leukemia Lymphoma[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor cell lymphoblastic leukaemia, not phenotyped[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute lymphoid leukaemia, disease[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], ALL, Childhood[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphoid leukaemia[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], Pre B Cell Leukemia[accessedResource: MSH:D015452][accessDate: 05-04-2011], Lymphoid leukemia, acute[accessedResource: ICD9:204.0][accessDate: 05-04-2011], Acute lymphoblastic leukaemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemia, L2 Lymphocytic[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor cell lymphoblastic leukemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemia, Pre-B-Cell[accessedResource: MSH:D015452][accessDate: 05-04-2011], Leukemia, Lymphocytic, Acute, L1[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor cell lymphoblastic leukaemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], [M]Acute lymphoid leukemia[accessedResource: SNOMEDCT:190034000][accessDate: 05-04-2011], Acute Lymphogenous Leukemia[accessedResource: NCIt:C3167][accessDate: 05-04-2011], A leukemia/lymphoma found predominately in children and adolescents and characterized by a high number of lymphoblasts and solid tumor lesions. Frequent sites involve LYMPH NODES, skin, and bones. It most commonly presents as leukemia.[accessedResource: MSH:D015452][accessDate: 05-04-2011], Lymphoma, Lymphoblastic[accessedResource: MSH:D054198][accessDate: 05-04-2011], ALL - Acute Lymphocytic Leukemia[accessedResource: NCIt:C3167][accessDate: 05-04-2011], Lymphocytic Leukemia, Acute[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute Lymphocytic Leukemias[accessedResource: NCIt:C3167][accessDate: 05-04-2011], [M]Acute lymphoid leukaemia[accessedResource: SNOMEDCT:190034000][accessDate: 05-04-2011], Pre-B-Cell Leukemias[accessedResource: MSH:D015452][accessDate: 05-04-2011], Acute lymphoblastic leukemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute Lymphoid Leukemia[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphatic leukemia[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute lymphoblastic leukaemia-lymphoma[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Precursor cell lymphoblastic leukemia (morphologic abnormality)[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Precursor B Cell Lymphoblastic Leukemia Lymphoma[accessedResource: MSH:D015452][accessDate: 05-04-2011], ALL - Acute lymphoblastic leukaemia[accessedResource: SNOMEDCT:91857003][accessDate: 05-04-2011], Precursor B-Cell Lymphoblastic Leukemia-Lymphoma[accessedResource: MSH:D015452][accessDate: 05-04-2011], Leukemia, Lymphoblastic[accessedResource: MSH:D054198][accessDate: 05-04-2011], Precursor Cell Lymphoblastic Leukemia-Lymphoma[accessedResource: MSH:D054198][accessDate: 05-04-2011], Leukemia, Lymphoblastic, Acute, L1[accessedResource: MSH:D054198][accessDate: 05-04-2011], Acute lymphatic leukaemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Leukemia, L1 Lymphocytic[accessedResource: MSH:D054198][accessDate: 05-04-2011], FAB L2[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011], Acute lymphoid leukemia, L2 type[accessedResource: SNOMEDCT:128822004][accessDate: 05-04-2011]
true
James Malone, Tomasz Adamusiak