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myelodysplastic syndrome

^ http://www.ebi.ac.uk/efo/EFO_0000198


Myelodysplastic syndromes are a class of syndromes which involve ineffective production (or dysplasia) of the myeloid class of blood cells.

A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)

Synonyms: Myelodysplastic Syndromes, Myelodysplastic Syndrome/Neoplasm, Hematopoeitic - Myelodysplastic Syndrome (MDS), Preleukemia, Smoldering Leukemia, Dysmyelopoietic Syndrome, Myelodysplastic Neoplasm, Myelodysplasia, MDS, Oligoblastic Leukemia

Term info

MSH definition citation

MSH:D009190, MSH:D011289

SNOMEDCT definition citation

SNOMEDCT:128623006

bioportal provenance

Myelodysplasia[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Myelodysplastic Syndrome/Neoplasm[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Hematopoeitic - Myelodysplastic Syndrome (MDS)[accessedResource: NCIt: C3247][accessDate: 05-04-2011], MDS[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Dysmyelopoietic Syndrome[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Myelodysplastic Syndromes[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Oligoblastic Leukemia[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Smoldering Leukemia[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Myelodysplastic Neoplasm[accessedResource: NCIt: C3247][accessDate: 05-04-2011], A clonal hematopoietic disorder characterized by dysplasia and ineffective hematopoiesis in one or more of the hematopoietic cell lines. The dysplasia may be accompanied by an increase in myeloblasts, but the number is less than 20%, which, according to the WHO guidelines, is the requisite threshold for the diagnosis of acute myeloid leukemia. It may occur de novo or as a result of exposure to alkylating agents and/or radiotherapy. (WHO, 2001)[accessedResource: NCIt: C3247][accessDate: 05-04-2011], Preleukemia[accessedResource: NCIt: C3247][accessDate: 05-04-2011]

term editor

Helen Parkinson

Term relations

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