A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). [ NCIT : P378 ]

Synonyms:

mature B-cell lymphocytic neoplasm

neoplasm of mature B-cells

mature B-cell neoplasm

This is just here as a test because I lose it

Term information

database cross reference
  • NCIT:C3457 (MONDO:directSiblingOf)
  • DOID:706 (MONDO:equivalentTo)
  • NCIT:C27910 (MONDO:equivalentTo)
  • UMLS:C1334633 (NCIT:C27910)
  • EFO:0000096 (MONDO:equivalentTo)
  • SCTID:269476000 (MONDO:equivalentTo)
  • ONCOTREE:MBN (MONDO:equivalentTo)
  • ICD9:202.0 (EFO:0000096)
  • MONDO:0004949
closeMatch
  • http://identifiers.org/snomedct/40411000
  • http://identifiers.org/snomedct/55150002
  • http://identifiers.org/snomedct/55020008
  • http://identifiers.org/snomedct/46744002
  • http://linkedlifedata.com/resource/umls/id/CL448793
comment
  • Editor note: is a non-hodgkin in ONCOTREE
exactMatch
  • http://linkedlifedata.com/resource/umls/id/C1334633
  • http://identifiers.org/snomedct/269476000
  • http://purl.obolibrary.org/obo/NCIT_C27910
  • http://purl.obolibrary.org/obo/DOID_706
gwas trait
  • true
has related synonym
  • mature B-cell neoplasms
id
  • EFO:0000096