Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells. [ http://purl.obolibrary.org/obo/go/references/0000031 MESH:A11.118.637.555.652 ]
Term information
- CALOHA:TS-0638
- FMA:62864
- BTO:0000876
Morphology: Mononuclear cell, diameter, 14 to 20 _M, N/C ratio 2:1-1:1. Nucleus may appear in variety of shapes: round, kidney, lobulated, or convoluted. Fine azurophilic granules present; markers: CD11b (shared with other myeloid cells), human: CD14, mouse: F4/80-mid,GR1-low; location: Blood, but can be recruited into tissues; role or process: immune & tissue remodelling; lineage: hematopoietic, myeloid.
Myeloid mononuclear recirculating leukocyte that can act as a precursor of tissue macrophages, osteoclasts and some populations of tissue dendritic cells.
Term relations
- myeloid leukocyte and bearer of some mononucleate and capable of some macrophage differentiation and capable of some osteoclast differentiation and capable of some myeloid dendritic cell differentiation
- mononuclear cell
- myeloid leukocyte
- progenitor cell
- develops from some promonocyte
- capable of some myeloid dendritic cell differentiation
- capable of some macrophage differentiation
- capable of some osteoclast differentiation