Juvenile amyotrophic lateral sclerosisGo to external page http://www.orpha.net/ORDO/Orphanet_300605
Juvenile amyotrophic lateral sclerosis (JALS) is a very rare severe motor neuron disease characterized by progressive upper and lower motor neuron degeneration causing facial spasticity, dysarthria, and gait disorders with onset before 25 years of age.
Synonyms: Juvenile Charcot disease JALS Juvenile Lou Gehrig disease
OMIM:602099, OMIM:205100, OMIM:614373, ICD-10:G12.2
- has_inheritance some autosomal recessive
- part_of some Genetic motor neuron disease
- has_age_of_onset some childhood
- present_in some Europe and has_point_prevalence_range some <1 / 1 000 000