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Multiple Sclerosis

^ http://purl.obolibrary.org/obo/NCIT_C3243


A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [ NCI ]

Synonyms: Multiple Sclerosis, multiple sclerosis

Term info

Subsets

NCIT_C90259, NCIT_C118464, NCIT_C118168, NCIT_C116977

ALT DEFINITION

A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and bladder control. Multiple sclerosis is thought to be an autoimmune disease in which the body's immune system destroys myelin. Myelin is a substance that contains both protein and fat (lipid), serving as a nerve insulator and helping in the transmission of nerve signals., An autoimmune demyelinating disease characterized by a relapsing-remitting or progressive pattern of central nervous system impairment.

Contributing Source

CTRP, MedDRA, NICHD

Display Name

Multiple Sclerosis

Has NICHD Parent

http://purl.obolibrary.org/obo/NCIT_C2934, http://purl.obolibrary.org/obo/NCIT_C2889

Legacy Concept Name

Multiple_Sclerosis

Maps To

Multiple sclerosis

NICHD Hierarchy Term

Multiple Sclerosis

Preferred Name

Multiple Sclerosis

Semantic Type

Disease or Syndrome

UMLS CUI

C0026769

code

C3243