A progressive autoimmune disorder affecting the central nervous system resulting in demyelination. Patients develop physical and cognitive impairments that correspond with the affected nerve fibers. [ NCI ]
Synonyms: Multiple Sclerosis, multiple sclerosis
NCIT_C90259, NCIT_C118464, NCIT_C118168, NCIT_C116977
A disorder of the central nervous system marked by weakness, numbness, a loss of muscle coordination, and problems with vision, speech, and bladder control. Multiple sclerosis is thought to be an autoimmune disease in which the body's immune system destroys myelin. Myelin is a substance that contains both protein and fat (lipid), serving as a nerve insulator and helping in the transmission of nerve signals., An autoimmune demyelinating disease characterized by a relapsing-remitting or progressive pattern of central nervous system impairment.
CTRP, MedDRA, NICHD
Disease or Syndrome