A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. [ NCI ]
Synonyms: leukemia, Leukemia, Disease, Leukemia NOS, Leukemia, Leukemias, General, Leukemia, NOS, Blood (Leukemia), Leukemias, LEUKEMIA, MALIGNANT
NCIT_C126659, NCIT_C99147, NCIT_C118464, NCIT_C118168, NCIT_C102905, NCIT_C138188, NCIT_C77526, NCIT_C103127, NCIT_C88025, NCIT_C138190, NCIT_C90259, NCIT_C61410, NCIT_C156966, NCIT_C156952, NCIT_C116977
Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream., A cancer of the blood or bone marrow that is characterized by increased production of abnormal blood cells., A progressive, proliferative disease of blood cells, originating from myeloid or lymphoid stem cells.
CTRP, CTEP, MedDRA, CDISC, NICHD, CPTAC
Other leukemia of unspecified cell type, Other specified leukemia, Leukemia of unspecified cell type, Other specified leukemias, Leukaemia, unspecified, Leukemia, unspecified not having achieved remission, Leukemia, Other leukaemias of specified cell type, Other specified leukemias not having achieved remission, Leukaemia of unspecified cell type, Unspecified leukemia, Other leukemia of unspecified cell type without mention of having achieved remission, Other specified leukaemias, Unspecified leukemia without mention of having achieved remission
- Malignant Neoplasm and Hematopoietic and Lymphoid Cell Neoplasm and Disease_Has_Primary_Anatomic_Site some Bone Marrow and Disease_Has_Abnormal_Cell some Leukemic Cell and Disease_Excludes_Finding some Solid Growth Pattern