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Leukemia

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A malignant (clonal) hematologic disorder, involving hematopoietic stem cells and characterized by the presence of primitive or atypical myeloid or lymphoid cells in the bone marrow and the blood. Leukemias are classified as acute or chronic based on the degree of cellular differentiation and the predominant cell type present. Leukemia is usually associated with anemia, fever, hemorrhagic episodes, and splenomegaly. Common leukemias include acute myeloid leukemia, chronic myelogenous leukemia, acute lymphoblastic or precursor lymphoblastic leukemia, and chronic lymphocytic leukemia. Treatment is vital to patient survival; untreated, the natural course of acute leukemias is normally measured in weeks or months, while that of chronic leukemias is more often measured in months or years. [ NCI ]

Synonyms: leukemia, Leukemia, Disease, Leukemia NOS, Leukemia, Leukemias, General, Leukemia, NOS, Blood (Leukemia), Leukemias, LEUKEMIA, MALIGNANT

Term info

Subsets

NCIT_C126659, NCIT_C99147, NCIT_C118464, NCIT_C118168, NCIT_C102905, NCIT_C138188, NCIT_C77526, NCIT_C103127, NCIT_C88025, NCIT_C138190, NCIT_C90259, NCIT_C61410, NCIT_C156966, NCIT_C156952, NCIT_C116977

ALT DEFINITION

Cancer that starts in blood-forming tissue such as the bone marrow and causes large numbers of blood cells to be produced and enter the bloodstream., A cancer of the blood or bone marrow that is characterized by increased production of abnormal blood cells., A progressive, proliferative disease of blood cells, originating from myeloid or lymphoid stem cells.

Contributing Source

CTRP, CTEP, MedDRA, CDISC, NICHD, CPTAC

Display Name

Leukemia

Has NICHD Parent

http://purl.obolibrary.org/obo/NCIT_C9305

ICD-O-3 Code

9800/3

Maps To

Other leukemia of unspecified cell type, Other specified leukemia, Leukemia of unspecified cell type, Other specified leukemias, Leukaemia, unspecified, Leukemia, unspecified not having achieved remission, Leukemia, Other leukaemias of specified cell type, Other specified leukemias not having achieved remission, Leukaemia of unspecified cell type, Unspecified leukemia, Other leukemia of unspecified cell type without mention of having achieved remission, Other specified leukaemias, Unspecified leukemia without mention of having achieved remission

Neoplastic Status

Malignant

Preferred Name

Leukemia

Semantic Type

Neoplastic Process

UMLS CUI

C0023418

code

C3161