Chorioretinal atrophy

^ http://purl.obolibrary.org/obo/HP_0000533

Atrophy of the choroid and retinal layers of the fundus. [ HPO:probinson pmid:20224472 ]

Synonyms: Chorioretinal thinning

Term info

database cross reference
  • UMLS:C4048273
  • SNOMEDCT_US:95686007

Choroidal sclerosis is a descriptive term applied to the ophthalmoscopic appearance of prominent white choroidal vessels in which the blood columns are not seen or are sheathed by white lines. Choroidal sclerosis is a term used to describe a group of genetically heterogeneous retinal dystrophies that share a common funduscopic phenotype of scalloped, well-circumscribed, and confluent chorioretinal atrophic lesions that extend beyond the macula. The term choroidal sclerosis was initially coined because of the sclerotic appearance of choroidal vessels which frequently appear white or light-yellow. However, histologic studies have demonstrated the term to be a misnomer as the principle abnormality is the loss of choriocapillaris, retinal pigment epithelium (RPE), and the outer retina in the absence of abnormal sclerotic changes in the choroidal vasculature. Therefore, we are making choroidal sclerosis a synonym of chorioretinal atrophy.

has alternative id

HP:0001150, HP:0007918, HP:0007884, HP:0007931

has obo namespace




Term relations

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