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motor neuron disease

^ http://www.ebi.ac.uk/efo/EFO_0003782


Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)

Synonyms: Motor Neuron Disease, Secondary, Motor Neuron Disease, Familial, Scleroses, Lateral, MOTOR NEURON DIS LOWER, Lateral Sclerosis, ANTERIOR HORN CELL DIS, Sclerosis, Lateral, MOTOR SYSTEM DIS, Anterior Horn Cell Disease, Familial Motor Neuron Disease, MOTOR NEURON DIS FAMILIAL, Neuron Diseases, Motor, Lateral Scleroses, LOWER MOTOR NEURON DIS, SECOND MOTOR NEURON DIS, Motor Neuron Disease, Lower, Motor System Diseases, Motor Neuron Diseases, MOTOR NEURON DIS UPPER, FAMILIAL MOTOR NEURON DIS, Motor System Disease, MOTOR NEURON DIS, Upper Motor Neuron Disease, Scleroses, Primary Lateral, Lower Motor Neuron Disease, MOTOR NEURON DIS SECOND, Neuron Disease, Motor, Motor Neuron Disease, Upper, UPPER MOTOR NEURON DIS, Secondary Motor Neuron Disease

Term info

SNOMEDCT definition citation

SNOMEDCT:37340000

bioportal provenance

MOTOR NEURON DIS SECOND[accessedResource: MSH:D016472][accessDate: 05-04-2011], Primary Lateral Sclerosis[accessedResource: MSH:D016472][accessDate: 05-04-2011], MOTOR SYSTEM DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Lateral Scleroses[accessedResource: MSH:D016472][accessDate: 05-04-2011], Lower Motor Neuron Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor System Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Upper Motor Neuron Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor Neuron Disease, Upper[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor Neuron Disease, Familial[accessedResource: MSH:D016472][accessDate: 05-04-2011], Anterior Horn Cell Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Sclerosis, Primary Lateral[accessedResource: MSH:D016472][accessDate: 05-04-2011], SECOND MOTOR NEURON DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Lateral Sclerosis[accessedResource: MSH:D016472][accessDate: 05-04-2011], Scleroses, Primary Lateral[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor Neuron Disease, Secondary[accessedResource: MSH:D016472][accessDate: 05-04-2011], Neuron Diseases, Motor[accessedResource: MSH:D016472][accessDate: 05-04-2011], Secondary Motor Neuron Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Diseases characterized by a selective degeneration of the motor neurons of the spinal cord, brainstem, or motor cortex. Clinical subtypes are distinguished by the major site of degeneration. In AMYOTROPHIC LATERAL SCLEROSIS there is involvement of upper, lower, and brainstem motor neurons. In progressive muscular atrophy and related syndromes (see MUSCULAR ATROPHY, SPINAL) the motor neurons in the spinal cord are primarily affected. With progressive bulbar palsy (BULBAR PALSY, PROGRESSIVE), the initial degeneration occurs in the brainstem. In primary lateral sclerosis, the cortical neurons are affected in isolation. (Adams et al., Principles of Neurology, 6th ed, p1089)[accessedResource: MSH:D016472][accessDate: 05-04-2011], MOTOR NEURON DIS LOWER[accessedResource: MSH:D016472][accessDate: 05-04-2011], ANTERIOR HORN CELL DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Sclerosis, Lateral[accessedResource: MSH:D016472][accessDate: 05-04-2011], FAMILIAL MOTOR NEURON DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor System Diseases[accessedResource: MSH:D016472][accessDate: 05-04-2011], Scleroses, Lateral[accessedResource: MSH:D016472][accessDate: 05-04-2011], Neuron Disease, Motor[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor Neuron Disease, Lower[accessedResource: MSH:D016472][accessDate: 05-04-2011], MOTOR NEURON DIS FAMILIAL[accessedResource: MSH:D016472][accessDate: 05-04-2011], Lateral Scleroses, Primary[accessedResource: MSH:D016472][accessDate: 05-04-2011], LOWER MOTOR NEURON DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], MOTOR NEURON DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Familial Motor Neuron Disease[accessedResource: MSH:D016472][accessDate: 05-04-2011], Primary Lateral Scleroses[accessedResource: MSH:D016472][accessDate: 05-04-2011], Motor Neuron Diseases[accessedResource: MSH:D016472][accessDate: 05-04-2011], MOTOR NEURON DIS UPPER[accessedResource: MSH:D016472][accessDate: 05-04-2011], UPPER MOTOR NEURON DIS[accessedResource: MSH:D016472][accessDate: 05-04-2011], Lateral Sclerosis, Primary[accessedResource: MSH:D016472][accessDate: 05-04-2011]

term editor

Tomasz Adamusiak

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