A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)

A neurodegenerative disease that results_from degeneration of the central nervous system that often impairs the sufferer's motor skills, speech, and other functions.

Synonyms:

Idiopathic PD

Parkinson's syndrome

Lewy Body Parkinson's Disease

LEWY BODY PARKINSON DIS

Primary Parkinsonism

PARKINSONS DIS IDIOPATHIC

Parkinson disease

Paralysis agitans

Parkinson's Disease, Lewy Body

Idiopathic Parkinson Disease

Parkinson's disease NOS

Parkinsonism, Primary

Parkinson's

Parkinson syndrome

Parkinson's disease NOS (disorder)

Parkinsonian disorder

IDIOPATHIC PARKINSON DIS

PARKINSONS DIS LEWY BODY

Parkinsons

Parkinsons disease

Parkinson's disease (disorder)

PARKINSON DIS

PARKINSONS DIS

Parkinson's Disease, Idiopathic

PARKINSON DIS IDIOPATHIC

Lewy Body Parkinson Disease

IDIOPATHIC PARKINSONS DIS

Idiopathic Parkinson's Disease

Parkinson Disease, Idiopathic