Acute promyelocytic leukemia (APL) is an aggressive form of acute myeloid leukemia (AML), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells. APL manifests with easy bruising, hemorrhagic diathesis and fatigue. [ Orphanet : 520 ]

An aggressive form of acute myeloid leukemia (AML), characterized by arrest of leukocyte differentiation at the promyelocyte stage, due to a specific chromosomal translocation t(15;17) in myeloid cells. APL manifests with easy bruising, hemorrhagic diathesis and fatigue. [ Orphanet : 520 ]

Synonyms:

acute myeloblastic leukemia type 3

acute promyelocytic leukemia

acute myeloid leukemia M3

leukemia, acute promyelocytic, somatic

acute promyelocytic leukemia with t(15;17)(q22;q12); PML/rara

AML with t(15;17)(q22;q12)

AML M3

APML

acute promyelocytic leukemia with t(15;17)(q22;q12); PML-rara

APML - acute promyelocytic leukemia

acute myeloblastic leukemia 3

acute promyelocytic leukemia with PML-rara

FAB M3

APL

promyelocytic leukemia

AML with t(15;17)(q22;q12);(PML/RARalpha) and variants

acute myeloid leukemia with t(15;17)(q22;q12);(PML/RARalpha) and variants

This is just here as a test because I lose it

Term information

database cross reference
  • GARD:0000538 (Orphanet-shared)
  • MONDO:0012883
  • NCIT:C3182 (MONDO:equivalentTo)
  • MedDRA:10001019 (Orphanet:520/e)
  • EFO:0000224 (MONDO:equivalentTo)
  • ICD10:C92.40 (DOID:0060318)
  • ICDO:9866/3 (NCIT:C3182)
  • MESH:D015473 (Orphanet:520)
  • OMIM:612376 (Orphanet:520)
  • UMLS:C0023487 (Orphanet:520)
  • MESH:D015473 (Orphanet:520/e)
  • OMIM:612376 (Orphanet:520/e)
  • GARD:0000538 (MONDO:equivalentTo)
  • UMLS:C0023487 (Orphanet:520/e)
  • MedDRA:10001019 (Orphanet:520)
  • ICD10:C92.4 (Orphanet:520)
  • Orphanet:520 (OMIM:612376)
  • SCTID:110004001 (MONDO:equivalentTo)
  • DOID:0060318 (MONDO:equivalentTo)
Subsets

ordo_disease

IAO 0000233
  • https://github.com/monarch-initiative/mondo/issues/4521
closeMatch
  • http://identifiers.org/meddra/10001019
exactMatch
  • http://identifiers.org/mesh/D015473
  • http://linkedlifedata.com/resource/umls/id/C0023487
  • http://identifiers.org/snomedct/110004001
  • http://purl.obolibrary.org/obo/DOID_0060318
  • http://purl.obolibrary.org/obo/Orphanet_520
  • http://purl.obolibrary.org/obo/NCIT_C3182
  • https://omim.org/entry/612376
excluded subClassOf
  • http://purl.obolibrary.org/obo/MONDO_0011118
has related synonym
  • APL
  • leukemia, acute promyelocytic
id
  • EFO:0000224

Term relations

Subclass of:
Related from: