PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=314-HM-24G)

Interfaces in PDB 6g9a crystal.
Space symmetry group: P 1 21 1. Resolution: 1.91 Å

FRAGMENT-BASED DISCOVERY OF A HIGHLY POTENT, ORALLY BIOAVAILABLE INHIBITOR WHICH MODULATES THE PHOSPHORYLATION AND CATALYTIC ACTIVITY OF ERK1/2

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`60`	`21`	`16640`	`x`	A	x-1,y,z-1	`1_454`	`60`	`18`	`16640`	`590.4`	`-4.0`	`0.275`	`3`	`0`	`0`	`0.000`
`2`		[ESQ]A:404	`32`	`1`	`668`	`f`	A	x,y,z	`1_555`	`57`	`25`	`16640`	`447.9`	`-6.1`	`0.376`	`2`	`0`	`0`	`0.013`
`3`		A	`48`	`12`	`16640`	`x`	A	-x,y-1/2,-z+1	`2_546`	`46`	`16`	`16640`	`443.0`	`-5.8`	`0.121`	`1`	`2`	`0`	`0.000`
`4`		A	`44`	`12`	`16640`	`x`	A	x-1,y,z	`1_455`	`46`	`13`	`16640`	`441.1`	`-3.2`	`0.335`	`6`	`0`	`0`	`0.000`
`5`		A	`18`	`5`	`16640`	`x`	A	-x+1,y-1/2,-z+2	`2_647`	`16`	`7`	`16640`	`157.6`	`-1.9`	`0.189`	`0`	`0`	`0`	`0.000`
`6`		A	`20`	`7`	`16640`	`x`	A	x,y,z-1	`1_554`	`13`	`5`	`16640`	`138.9`	`0.4`	`0.661`	`1`	`0`	`0`	`0.000`
`7`		[SO4]A:403	`5`	`1`	`186`	`f`	A	x,y,z	`1_555`	`18`	`9`	`16640`	`103.0`	`-15.9`	`0.847`	`6`	`0`	`0`	`0.033`
`8`		[SO4]A:401	`5`	`1`	`186`	`f`	A	x,y,z	`1_555`	`11`	`5`	`16640`	`98.4`	`-13.4`	`0.920`	`5`	`0`	`0`	`0.028`
`9`		[SO4]A:402	`5`	`1`	`185`	`f`	A	x,y,z	`1_555`	`12`	`3`	`16640`	`90.7`	`-13.2`	`0.763`	`3`	`0`	`0`	`0.026`
`10`		A	`5`	`2`	`16640`	`x`	A	-x+1,y-1/2,-z+1	`2_646`	`5`	`2`	`16640`	`26.6`	`0.5`	`0.748`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe