PDBe < PISA < EMBL-EBI

PISA Interface List.

Session Map (id=191-66-IL2)

Interfaces in PDB 4r5y crystal.
Space symmetry group: P 21 21 21. Resolution: 3.50 Å

THE COMPLEX STRUCTURE OF BRAF V600E KINASE DOMAIN WITH A NOVEL BRAF INHIBITOR

Interfaces

##			Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
Id	NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
1	`1`		B	`118`	`31`	`13048`	`◊`	A	x,y,z	`1_555`	`118`	`31`	`12930`	`1186.1`	`-0.7`	`0.714`	`13`	`8`	`0`	`0.000`
2	`2`		A	`58`	`20`	`12930`	`x`	A	x-1/2,-y+1/2,-z	`4_455`	`67`	`25`	`12930`	`587.1`	`1.0`	`0.700`	`12`	`0`	`0`	`0.000`
	`3`		B	`67`	`24`	`13048`	`x`	B	x-1/2,-y-1/2,-z	`4_445`	`70`	`26`	`13048`	`575.2`	`1.4`	`0.768`	`10`	`0`	`0`	`0.000`
	*Average:*													`581.1`	`1.2`	`0.734`	`11`	`0`	`0`	`0.000`
3	`4`		[3K3]A:801	`35`	`1`	`687`	`◊`	A	x,y,z	`1_555`	`63`	`26`	`12930`	`503.7`	`3.7`	`0.148`	`3`	`0`	`0`	`0.000`
	`5`		[3K3]B:801	`35`	`1`	`687`	`◊`	B	x,y,z	`1_555`	`66`	`26`	`13048`	`498.5`	`5.0`	`0.248`	`2`	`0`	`0`	`0.000`
	*Average:*													`501.1`	`4.4`	`0.198`	`3`	`0`	`0`	`0.000`
4	`6`		B	`33`	`13`	`13048`	`◊`	A	-x+1,y-1/2,-z-1/2	`3_644`	`30`	`11`	`12930`	`285.4`	`-2.2`	`0.324`	`0`	`0`	`0`	`0.000`
5	`7`		B	`21`	`7`	`13048`	`x`	B	x-1,y,z	`1_455`	`15`	`6`	`13048`	`157.2`	`2.5`	`0.865`	`2`	`2`	`0`	`0.000`
	`8`		A	`18`	`6`	`12930`	`x`	A	x-1,y,z	`1_455`	`15`	`6`	`12930`	`145.7`	`3.3`	`0.907`	`2`	`1`	`0`	`0.000`
	*Average:*													`151.4`	`2.9`	`0.886`	`2`	`2`	`0`	`0.000`
6	`9`		B	`3`	`2`	`13048`	`◊`	A	-x,y-1/2,-z-1/2	`3_544`	`4`	`3`	`12930`	`7.8`	`-0.0`	`0.614`	`0`	`0`	`0`	`0.000`
7	`10`		B	`1`	`1`	`13048`	`f`	[3K3]B:801	x-1/2,-y-1/2,-z	`4_445`	`1`	`1`	`687`	`0.6`	`0.0`	`0.526`	`0`	`0`	`0`	`0.000`

PDBe PISA v1.52 [20/10/2014]

Protein Data Bank
in Europe