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PISA Interface List.

Session Map (id=889-H4-6A4)

Interfaces in PDB 4r1v crystal.
Space symmetry group: P 1 21 1. Resolution: 1.20 Å

IDENTIFICATION AND OPTIMIZATION OF PYRIDAZINONES AS POTENT AND SELECTIVE C-MET KINASE INHIBITORS

Interfaces

##		Structure 1				×	Structure 2						interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
NN	«»	Range	ⁱN_at	ⁱN_res	Surface Å²	×	Range	Symmetry op-n	Sym.ID	ⁱN_at	ⁱN_res	Surface Å²	interface area, Å²	ΔⁱG kcal/mol	ΔⁱG P-value	N_HB	N_SB	N_DS	CSS
`1`		A	`82`	`28`	`14565`	`x`	A	x-1,y,z	`1_455`	`77`	`23`	`14565`	`717.2`	`2.4`	`0.827`	`10`	`5`	`0`	`0.000`
`2`		[3E8]A:1401	`34`	`1`	`762`	`◊`	A	x,y,z	`1_555`	`60`	`24`	`14565`	`471.0`	`3.2`	`0.414`	`2`	`0`	`0`	`0.000`
`3`		A	`49`	`16`	`14565`	`x`	A	x,y-1,z	`1_545`	`46`	`14`	`14565`	`412.4`	`3.1`	`0.798`	`7`	`2`	`0`	`0.000`
`4`		[GBL]A:1404	`6`	`1`	`219`	`f`	A	x,y,z	`1_555`	`25`	`9`	`14565`	`143.4`	`-2.4`	`0.561`	`1`	`0`	`0`	`0.040`
`5`		[GBL]A:1402	`6`	`1`	`220`	`f`	A	x,y,z	`1_555`	`26`	`11`	`14565`	`136.5`	`-2.3`	`0.574`	`2`	`0`	`0`	`0.045`
`6`		[GBL]A:1403	`6`	`1`	`220`	`◊`	A	x,y,z	`1_555`	`14`	`6`	`14565`	`113.4`	`-0.5`	`0.779`	`1`	`0`	`0`	`0.000`
`7`		A	`3`	`1`	`14565`	`f`	[GBL]A:1403	x-1,y,z	`1_455`	`3`	`1`	`220`	`30.8`	`-1.0`	`0.363`	`0`	`0`	`0`	`0.014`
`8`		A	`1`	`1`	`14565`	`f`	[3E8]A:1401	x-1,y,z	`1_455`	`1`	`1`	`762`	`3.8`	`-0.1`	`0.414`	`0`	`0`	`0`	`0.002`

PDBe PISA v1.52 [20/10/2014]