1. MetaboLights
  2. Analysis Tools

Integrated Analysis Tools

*We are currently developing this section


MetaboAnalyst is a user-friendly, comprehensive web-based analytical pipeline for high-throughput metabolomics studies. Our version of MetaboAnalyst 3.0 is coupled with EBI's in-house R Cloud to faciliate compute intensive data analysis.



References:

Xia, J., Sinelnikov, I., Han, B., and Wishart, D.S. (2015). MetaboAnalyst 3.0 - making metabolomics more meaningful . Nucl. Acids Res. (DOI: 10.1093/nar/gkv380).

Xia, J., Mandal, R., Sinelnikov, I., Broadhurst, D., and Wishart, D.S. (2012). MetaboAnalyst 2.0 - a comprehensive server for metabolomic data analysis . Nucl. Acids Res. 40, W127-W133.

Xia, J., Psychogios, N., Young, N. and Wishart, D.S. (2009). MetaboAnalyst: a web server for metabolomic data analysis and interpretation. Nucl. Acids Res. 37, W652-660

LipidHome is a database of theoretical lipid structures derived from a seed set of lipid sub classes and some lipid chemical space constraints agreed upon with experts in the field. Lipids are organised according to a combination of the LIPID MAPS ontology and the recent publication by the LipidomicNet consortium.

References:

Fahy, E., Subramaniam, S., Murphy, R. C., Nishijima, M., Raetz, C. R. H., Shimizu, T., et al. (2009). Update of the LIPID MAPS comprehensive classification system for lipids. Journal of Lipid Research, 50 Suppl, S9–14.

Foster, J. M., Moreno, P., Fabregat, A., Hermjakob, H., Steinbeck, C., Apweiler, R., et al. (2013). LipidHome: a database of theoretical lipids optimized for high throughput mass spectrometry lipidomics. PLoS ONE, 8(5), e61951.

Liebisch G, Vizcaíno JA, Koefeler H, Troztmueller M, Griffiths WJ, Schmitz G, Spener F, Wakelam MJO (2013). Shorthand notation for lipid structures derived from mass spectrometry. J Lipid Res, 54(6):1523-30.

Study Factor Distribution BETA*

Parallel coordinates are a common way of visualizing high-dimensional study factors / analysing multivariate study data.
* may be unstable