Small-molecule inhibitor: RO4929097

Summary Literature

Name

Common name: RO4929097

Inhibition

Peptidases inhibited: Inhibits processing of Notch, a gamma-secretase activity attributable to presenilin 1.
Pharmaceutical relevance: There is preliminary evidence of clinical antitumor activity (Tolcher et al., 2012).

Chemistry

CID at PubChem: 49867930
Structure