Small-molecule inhibitor: edoxaban
Name
- Common name
- edoxaban
- Other names
- DU 176b; DU-176; DU-176b; DU176b; edoxaban tosylate; Lixiana; Savaysa
Inhibition
- Peptidases inhibited
- Inhibits coagulation factor Xa. In vitro, DU-176b inhibited free factor Xa with Ki 0.6 nM (Furugohri et al., 2008).
- Pharmaceutical relevance
- Edoxaban has potential for the clinical management of coagulation disorders (Samama et al., 2010).
Chemistry
- CID at PubChem
- 25022378
- Structure
- Formula weight
- 738
![[edoxaban (S01.216 inhibitor) structure ]](http://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&cid=25022378)
