Small-molecule inhibitor: apixaban

Summary Structure Literature

Name

Common name: apixaban
Other names: BMS-562247; Eliquis

Inhibition

History: The development of apixaban was described by Pinto et al., 2007.
Peptidases inhibited: Inhibits coagulation factor Xa.

Chemistry

CID at PubChem: 10182969
Structure
Chemical/biochemical name: 1-(4-methoxyphenyl)-7-oxo-6-(4-(2-oxopiperidin-1-yl)phenyl)-4,5,6,7-tetrahydro-1H-pyrazolo[3,4-c]pyridine-3-carboxamide
Formula weight: 459