Small-molecule inhibitor: L-658,758
Name
- Common name
- L-658,758
Inhibition
- Peptidases inhibited
- Inhibits leukocyte elastase, elastase-2 (Knight et al., 1992).
- Mechanism
- The mechanism of inhibition by this cephalosporin derivative involves initial formation of a Michaelis complex followed by acylation of the active site serine (Knight et al., 1992).
Chemistry
- CID at PubChem
- 121963
- Structure
- Chemical/biochemical name
- 1-[[3-(acetoxymethyl)-7 alpha-methoxy-8-oxo-5-thia-1-azabicyclo [4.2.0]oct-2-en-2-yl]carbonyl]proline S,S-dioxide
![[L-658,758 (S01.131 inhibitor) structure ]](http://pubchem.ncbi.nlm.nih.gov/image/imgsrv.fcgi?t=l&cid=121963)
