Literature for NVP-DPP728 (S09.003 inhibitor)

(Topics flags: I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2002
1. Ahren,B., Simonsson,E., Larsson,H., Landin-Olsson,M., Torgeirsson,H., Jansson,P.A., Sandqvist,M., Bavenholm,P., Efendic,S., Eriksson,J.W., Dickinson,S. and Holmes,D.
   Inhibition of dipeptidyl peptidase IV improves metabolic control over a 4-week study period in type 2 diabetes
   Diabetes Care25, 869-875. PubMed  Europe PubMed DOI  I
2. Deacon,C.F., Wamberg,S., Bie,P., Hughes,T.E. and Holst,J.J.
   Preservation of active incretin hormones by inhibition of dipeptidyl peptidase IV suppresses meal-induced incretin secretion in dogs
   J Endocrinol172, 355-362. PubMed  Europe PubMed DOI  I
3. Mitani,H., Takimoto,M. and Kimura,M.
   Dipeptidyl peptidase IV inhibitor NVP-DPP728 ameliorates early insulin response and glucose tolerance in aged rats but not in aged Fischer 344 rats lacking its enzyme activity
   Jpn J Pharmacol88, 451-458. PubMed  Europe PubMed DOI  I
4. Reimer,M.K., Holst,J.J. and Ahren,B.
   Long-term inhibition of dipeptidyl peptidase IV improves glucose tolerance and preserves islet function in mice
   Eur J Endocrinol146, 717-727. PubMed  Europe PubMed  I
5. [YEAR:6-6-2002]Villhauer,E.B., Brinkman,J.A., Naderi,G.B., Dunning,B.E., Mangold,B.L., Mone,M.D., Russell,M.E., Weldon,S.C. and Hughes,T.E.
   1-[2-[(5-Cyanopyridin-2-yl)amino]ethylamino]acetyl-2-(S)-pyrrolidinecarbonitrile: a potent, selective, and orally bioavailable dipeptidyl peptidase IV inhibitor with antihyperglycemic properties
   J Med Chem45, 2362-2365. PubMed  Europe PubMed DOI  I
1999
6. [YEAR:7-9-1999]Hughes,T.E., Mone,M.D., Russell,M.E., Weldon,S.C. and Villhauer,E.B.
   NVP-DPP728 (1-[[[2-[(5-cyanopyridin-2-yl) amino]ethyl] amino] acetyl]-2-cyano-(S)-pyrrolidine), a slow-binding inhibitor of dipeptidyl peptidase IV
   Biochemistry38, 11597-11603. PubMed  Europe PubMed DOI  I