Literature for NB-360 (A01.004 inhibitor)

Summary Literature

(Topics flags: I Inhibitor, K Knockout. To select only the references relevant to a single topic, click the link above. See explanation.)

    2019
  1. Dierich,M., Hartmann,S., Dietrich,N., Moeser,P., Brede,F., Johnson Chacko,L., Tziridis,K., Schilling,A., Krauss,P., Hessler,S., Karch,S., Schrott-Fischer,A., Blumer,M., Birchmeier,C., Oliver,D., Moser,T., Schulze,H., Alzheimer,C., Leitner,M.G. and Huth,T.
    beta-secretase BACE1 is required for normal cochlear function
    J Neurosci39, 9013-9027. PubMed  Europe PubMed DOI  K  I
  2. 2016
  3. Shimshek,D.R., Jacobson,L.H., Kolly,C., Zamurovic,N., Balavenkatraman,K.K., Morawiec,L., Kreutzer,R., Schelle,J., Jucker,M., Bertschi,B., Theil,D., Heier,A., Bigot,K., Beltz,K., Machauer,R., Brzak,I., Perrot,L. and Neumann,U.
    Pharmacological BACE1 and BACE2 inhibition induces hair depigmentation by inhibiting PMEL17 processing in mice
    Sci Rep6, 21917-21917. PubMed  Europe PubMed DOI  I
  4. 2015
  5. Neumann,U., Rueeger,H., Machauer,R., Veenstra,S.J., Lueoend,R.M., Tintelnot-Blomley,M., Laue,G., Beltz,K., Vogg,B., Schmid,P., Frieauff,W., Shimshek,D.R., Staufenbiel,M. and Jacobson,L.H.
    A novel BACE inhibitor NB-360 shows a superior pharmacological profile and robust reduction of amyloid-beta and neuroinflammation in APP transgenic mice
    Mol Neurodegener10, 44-44. PubMed  Europe PubMed DOI  I