Literature for GW475151 (S01.131 inhibitor)

(Topics flags: S Structure, I Inhibitor. To select only the references relevant to a single topic, click the link above. See explanation.)

2002
1. [YEAR:29-8-2002]Macdonald,S.J., Dowle,M.D., Harrison,L.A., Clarke,G.D., Inglis,G.G., Johnson,M.R., Shah,P., Smith,R.A., Amour,A., Fleetwood,G., Humphreys,D.C., Molloy,C.R., Dixon,M., Godward,R.E., Wonacott,A.J., Singh,O.M., Hodgson,S.T. and Hardy,G.W.
   Discovery of further pyrrolidine trans-lactams as inhibitors of human neutrophil elastase (HNE) with potential as development candidates and the crystal structure of HNE complexed with an inhibitor (GW475151)
   J Med Chem45, 3878-3890. PubMed  Europe PubMed DOI  S  I