Literature for peptidase C19.068: ubiquitin-specific peptidase 48

(Topics flags: M Mutation, I Inhibitor, K Knockout, V Review. To select only the references relevant to a single topic, click the link above. See explanation.)

2025
1. Zhang,X., Zhao,J., Qi,G., Chen,Y., Guo,X., Zhang,J., Chen,S., Xu,X., Feng,J., Zhang,Q., Gao,B., Wang,Z. and Jin,J.
   USP48 inhibits colorectal cancer progression and promotes M1-like macrophage polarization by stabilizing TAK1
   Exp Cell Res446, 114469-114469. PubMed  Europe PubMed DOI
2. Zhang,Z., Lin,X., Yang,Y., Wang,X., Wang,Y., Huang,X., Hong,M., Gao,W., He,H., You,M.J., Yang,Y. and Kong,G.
   Caspase 3-specific cleavage of ubiquitin-specific peptidase 48 enhances drug-induced apoptosis in AML
   Cancer Biol Ther26, 2459426-2459426. PubMed  Europe PubMed DOI  K
2024
3. Chen,J., Lin,C., Huang,X. and Bian,W.
   Baicalin enhances proliferation and reduces inflammatory-oxidative stress effect in H(2)O(2)-induced granulosa cells apoptosis via USP48 protein regulation
   BMC Complement Med Ther24, 42-42. PubMed  Europe PubMed DOI  K
4. Cheng,C., Yao,H., Li,H., Liu,J., Liu,Z., Wu,Y., Zhu,L., Hu,H., Fang,Z. and Wu,L.
   Blockade of the deubiquitinating enzyme USP48 degrades oncogenic HMGA2 and inhibits colorectal cancer invasion and metastasis
   Acta Pharm Sin B14, 1624-1643. PubMed  Europe PubMed DOI
5. Xie,Y., Tan,L., Wu,K., Li,D. and Li,C.
   miR-26b-5p Affects the Progression of Acute Myeloid Leukemia by Regulating the USP48-Mediated Wnt/beta-Catenin Pathway
   Crit Rev Eukaryot Gene Expr34, 33-44. PubMed  Europe PubMed DOI  K
6. Zhang,G., Yu,J. and Wan,Y.
   USP48 deubiquitination stabilizes SLC1A5 to inhibit retinal pigment epithelium cell inflammation, oxidative stress and ferroptosis in the progression of diabetic retinopathy
   J Bioenerg Biomembr56, 311-321. PubMed  Europe PubMed DOI  K
7. Zhang,M., Liu,M., Ren,Z., Wang,W., Upadhyay,K., Asico,L.A., Armando,I., Jia,Y., Wang,P., Xue,Y. and Wang,X.
   DOPAMINE D4 RECEPTOR DOWN-REGULATES RENAL SODIUM CHLORIDE COTRANSPORTER VIA UBIQUITINATION-ASSOCIATED LYSOSOME DEGRADATION
   bioRxiv PubMed  Europe PubMed DOI  K
2023
8. Bohm,K., Schulze-Niemand,E., Kahne,T., Siddiqui,E., Tager,C., Ramsbeck,D., Buchholz,M. and Naumann,M.
   Synthesis and structure-activity relationships of USP48 deubiquitinylase inhibitors
   Arch Pharm (Weinheim)356, e2200661-e2200661. PubMed  Europe PubMed DOI  I
9. Ma,Q., Ruan,H., Dai,H. and Yao,W.D.
   USP48/USP31 Is a Nuclear Deubiquitinase that Potently Regulates Synapse Remodeling
   bioRxiv PubMed  Europe PubMed DOI
10. Ren,Y., Feng,M., Hao,X., Liu,X., Li,J., Li,P., Gao,J., Qi,Q., Du,L., Wang,C., Wang,Q. and Wang,Y.
    USP48 Stabilizes Gasdermin E to Promote Pyroptosis in Cancer
    Cancer Res83, 1074-1093. PubMed  Europe PubMed DOI
2022
11. Jantaree,P., Chaithongyot,S., Sokolova,O. and Naumann,M.
    USP48 and A20 synergistically promote cell survival in Helicobacter pylori infection
    Cell Mol Life Sci79, 461-461. PubMed  Europe PubMed DOI
12. Mirra,S., Sanchez-Bellver,L., Casale,C., Pescatore,A. and Marfany,G.
    Ubiquitin Specific Protease USP48 Destabilizes NF-kappaB/p65 in Retinal Pigment Epithelium Cells
    Int J Mol Sci23, PubMed  Europe PubMed DOI
13. Zhang,P., Li,L., Wang,B., Ran,X., Yang,S., Luo,Y., Li,Y., Wang,Z., Liu,Y. and Zhu,B.
    miR-489-3p promotes malignant progression of non-small cell lung cancer through the inactivation of Wnt/beta-catenin signaling pathway via regulating USP48
    Respir Res23, 93-93. PubMed  Europe PubMed DOI
2021
14. Antao,A.M., Kaushal,K., Das,S., Singh,V., Suresh,B., Kim,K.S. and Ramakrishna,S.
    USP48 Governs Cell Cycle Progression by Regulating the Protein Level of Aurora B
    Int J Mol Sci22, PubMed  Europe PubMed DOI
15. Bassani,S., Beelen,E., Rossel,M., Voisin,N., Morgan,A., Arribat,Y., Chatron,N., Chrast,J., Cocca,M., Delprat,B., Faletra,F., Giannuzzi,G., Guex,N., Machavoine,R., Pradervand,S., Smits,J.J., van de Kamp,J.M., Ziegler,A., Amati,F., Marlin,S., Kremer,H., Locher,H., Maurice,T., Gasparini,P., Girotto,G. and Reymond,A.
    Variants in USP48 encoding ubiquitin hydrolase are associated with autosomal dominant non-syndromic hereditary hearing loss
    Hum Mol Genet PubMed  Europe PubMed DOI
16. Du,L., Li,Y., Kang,M., Feng,M., Ren,Y., Dai,H., Wang,Y., Wang,Y. and Tang,B.
    USP48 is upregulated by Mettl14 to attenuate hepatocellular carcinoma via regulating SIRT6 stabilization
    Cancer Res PubMed  Europe PubMed DOI
2020
17. Chang,M., Yang,C., Bao,X. and Wang,R.
    Genetic and Epigenetic Causes of Pituitary Adenomas
    Front Endocrinol (Lausanne)11, 596554-596554. PubMed  Europe PubMed DOI  V
18. Dubiel,W., Chaithongyot,S., Dubiel,D. and Naumann,M.
    The COP9 Signalosome: A Multi-DUB Complex
    Biomolecules10, 1082-1082. PubMed  Europe PubMed DOI
19. Lei,X., Li,X., Chen,H. and Liu,Z.
    USP48 Sustains chemoresistance and metastasis in ovarian cancer
    Curr Cancer Drug Targets PubMed  Europe PubMed DOI
2019
20. Sbiera,S., Kunz,M., Weigand,I., Deutschbein,T., Dandekar,T. and Fassnacht,M.
    The new genetic landscape of Cushing's disease: deubiquitinases in the spotlight
    Cancers (Basel)11, PubMed  Europe PubMed DOI  M
2018
21. Li,S., Wang,D., Zhao,J., Weathington,N.M., Shang,D. and Zhao,Y.
    The deubiquitinating enzyme USP48 stabilizes TRAF2 and reduces E-cadherin-mediated adherens junctions
    FASEB J32, 230-242. PubMed  Europe PubMed DOI
22. Liu,Q., Wu,Y., Qin,Y., Hu,J., Xie,W., Qin,F.X. and Cui,J.
    Broad and diverse mechanisms used by deubiquitinase family members in regulating the type I interferon signaling pathway during antiviral responses
    Sci Adv4, eaar2824-eaar2824. PubMed  Europe PubMed DOI
23. Liu,Y.L., Yan,J., Zheng,J. and Tian,Q.B.
    (938)RHRK(941) is responsible for ubiquitin specific protease 48 nuclear translocation which can stabilize NF-kappaB (p65) in the nucleus
    Gene669, 77-81. PubMed  Europe PubMed DOI
24. Uckelmann,M., Densham,R.M., Baas,R., Winterwerp,H.H.K., Fish,A., Sixma,T.K. and Morris,J.R.
    USP48 restrains resection by site-specific cleavage of the BRCA1 ubiquitin mark from H2A
    Nat Commun9, 229-229. PubMed  Europe PubMed DOI
2017
25. Cetkovska,K., Sustova,H. and Uldrijan,S.
    Ubiquitin-specific peptidase 48 regulates Mdm2 protein levels independent of its deubiquitinase activity
    Sci Rep7, 43180-43180. PubMed  Europe PubMed DOI
26. Zhou,A., Lin,K., Zhang,S., Ma,L., Xue,J., Morris,S.A., Aldape,K.D. and Huang,S.
    Gli1-induced deubiquitinase USP48 aids glioblastoma tumorigenesis by stabilizing Gli1
    EMBO Rep18, 1318-1330. PubMed  Europe PubMed DOI
2015
27. Schweitzer,K. and Naumann,M.
    CSN-associated USP48 confers stability to nuclear NF-kappaB/RelA by trimming K48-linked Ub-chains
    Biochim Biophys Acta1853, 453-469. PubMed  Europe PubMed DOI
2014
28. Armando,I., Villar,V.A., Jones,J.E., Lee,H., Wang,X., Asico,L.D., Yu,P., Yang,J., Escano,C.S., Jr., Pascua-Crusan,A.M., Felder,R.A. and Jose,P.A.
    Dopamine D3 receptor inhibits the ubiquitin-specific peptidase 48 to promote NHE3 degradation
    FASEB J28, 1422-1434. PubMed  Europe PubMed DOI
2009
29. Schmitz,R.J., Tamada,Y., Doyle,M.R., Zhang,X. and Amasino,R.M.
    Histone H2B deubiquitination is required for transcriptional activation of FLOWERING LOCUS C and for proper control of flowering in Arabidopsis
    Plant Physiol149, 1196-1204. PubMed  Europe PubMed DOI  M
2008
30. Luo,M., Luo,M.Z., Buzas,D., Finnegan,J., Helliwell,C., Dennis,E.S., Peacock,W.J. and Chaudhury,A.
    Ubiquitin-specific protease 26 is required for seed development and the repression of PHERES1 in Arabidopsis
    Genetics180, 229-236. PubMed  Europe PubMed DOI
2007
31. Sridhar,V.V., Kapoor,A., Zhang,K., Zhu,J., Zhou,T., Hasegawa,P.M., Bressan,R.A. and Zhu,J.K.
    Control of DNA methylation and heterochromatic silencing by histone H2B deubiquitination
    Nature447, 735-738. PubMed  Europe PubMed DOI
2004
32. [YEAR:30-1-2004]Quesada,V., Diaz-Perales,A., Gutierrez-Fernandez,A., Garabaya,C., Cal,S. and Lopez-Otin,C.
    Cloning and enzymatic analysis of 22 novel human ubiquitin-specific proteases
    Biochem Biophys Res Commun314, 54-62. PubMed  Europe PubMed DOI
2003
33. Tian,Q.B., Okano,A., Nakayama,K., Miyazawa,S., Endo,S. and Suzuki,T.
    A novel ubiquitin-specific protease, synUSP, is localized at the post-synaptic density and post-synaptic lipid raft
    J Neurochem87, 665-675. PubMed  Europe PubMed DOI