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Literature for peptidase S01.215: coagulation factor VIIa

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(References are filtered for relevance to Structure. To remove the filter click here. See explanation.)

    2019
  1. Sorensen,A.B., Madsen,J.J., Frimurer,T.M., Overgaard,M.T., Gandhi,P.S., Persson,E. and Olsen,O.H.
    Allostery in coagulation factor VIIa revealed by ensemble refinement of crystallographic structures
    Biophys J116, 1823-1835. PubMed  Europe PubMed DOI  S
    2. 2015
  2. Glunz,P.W., Cheng,X., Cheney,D.L., Weigelt,C.A., Wei,A., Luettgen,J.M., Wong,P.C., Wexler,R.R. and Priestley,E.S.
    Design and synthesis of potent, selective phenylimidazole-based FVIIa inhibitors
    Bioorg Med Chem Lett25, 2169-2173. PubMed  Europe PubMed DOI  S  I
    3. 2010
  3. Lee,C.J., Chandrasekaran,V., Wu,S., Duke,R.E. and Pedersen,L.G.
    Recent estimates of the structure of the factor VIIa (FVIIa)/tissue factor (TF) and factor Xa (FXa) ternary complex
    Thromb Res125 Suppl 1, S7-S7. PubMed  Europe PubMed DOI  S
  4. Mosbaek,C.R., Nolan,D., Persson,E., Svergun,D.I., Bukrinsky,J.T. and Vestergaard,B.
    Extensive small-angle X-ray scattering studies of blood coagulation factor VIIa reveal interdomain flexibility
    Biochemistry49, 9739-9745. PubMed  Europe PubMed DOI  S
    5. 2007
  5. Krishnan,R., Kotian,P.L., Chand,P., Bantia,S., Rowland,S. and Babu,Y.S.
    Probing the S2 site of factor VIIa to generate potent and selective inhibitors: the structure of BCX-3607 in complex with tissue factor-factor VIIa
    Acta Crystallogr D Biol Crystallogr63, 689-697. PubMed  Europe PubMed DOI  S  I
    6. 2006
  6. [YEAR:6-6-2006]Bajaj,S.P., Schmidt,A.E., Agah,S., Bajaj,M.S. and Padmanabhan,K.
    High resolution structures of p-aminobenzamidine- and benzamidine-VIIa/soluble tissue factor: unpredicted conformation of the 192-193 peptide bond and mapping of Ca2+, Mg2+, Na+, and Zn2+ sites in factor VIIa
    J Biol Chem281, 24873-24888. PubMed  Europe PubMed DOI  S  I
    7. 2005
  7. [YEAR:1-2-2005]Kadono,S., Sakamoto,A., Kikuchi,Y., Oh-eda,M., Yabuta,N., Koga,T., Hattori,K., Shiraishi,T., Haramura,M., Kodama,H., Ono,Y., Esaki,T., Sato,H., Watanabe,Y., Itoh,S., Ohta,M. and Kozono,T.
    Structure of human factor VIIa/tissue factor in complex with a peptide-mimetic inhibitor: high selectivity against thrombin by introducing two charged groups in P2 and P4
    Acta Crystallograph Sect F Struct Biol Cryst Commun61, 169-173. PubMed  Europe PubMed DOI  S  I
  8. Kadono,S., Sakamoto,A., Kikuchi,Y., Oh-eda,M., Yabuta,N., Yoshihashi,K., Kitazawa,T., Suzuki,T., Koga,T., Hattori,K., Shiraishi,T., Haramura,M., Kodama,H., Ono,Y., Esaki,T., Sato,H., Watanabe,Y., Itoh,S., Ohta,M. and Kozono,T.
    Novel interactions of large P3 moiety and small P4 moiety in the binding of the peptide mimetic factor VIIa inhibitor
    Biochem Biophys Res Commun326, 859-865. PubMed  Europe PubMed DOI  S  I
  9. Kohrt,J.T., Filipski,K.J., Cody,W.L., Cai,C., Dudley,D.A., Van Huis,C.A., Willardsen,J.A., Rapundalo,S.T., Saiya-Cork,K., Leadley,R.J., Narasimhan,L., Zhang,E., Whitlow,M., Adler,M., McLean,K., Chou,Y.L., McKnight,C., Arnaiz,D.O., Shaw,K.J., Light,D.R. and Edmunds,J.J.
    The discovery of fluoropyridine-based inhibitors of the Factor VIIa/TF complex
    Bioorg Med Chem Lett15, 4752-4756. PubMed  Europe PubMed DOI  S  I
  10. Schweitzer,B.A., Neumann,W.L., Rahman,H.K., Kusturin,C.L., Sample,K.R., Poda,G.I., Kurumbail,R.G., Stevens,A.M., Stegeman,R.A., Stallings,W.C. and South,M.S.
    Structure-based design and synthesis of pyrazinones containing novel P1 'side pocket' moieties as inhibitors of TF/VIIa
    Bioorg Med Chem Lett15, 3006-3011. PubMed  Europe PubMed DOI  S  I
  11. Zbinden,K.G., Obst-Sander,U., Hilpert,K., Kuhne,H., Banner,D.W., Bohm,H.J., Stahl,M., Ackermann,J., Alig,L., Weber,L., Wessel,H.P., Riederer,M.A., Tschopp,T.B. and Lave,T.
    Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors
    Bioorg Med Chem Lett15, 5344-5352. PubMed  Europe PubMed DOI  S  I
    12. 2004
  12. [YEAR:26-11-2004]Kadono,S., Sakamoto,A., Kikuchi,Y., Oh-eda,M., Yabuta,N., Koga,T., Hattori,K., Shiraishi,T., Haramura,M., Kodama,H., Esaki,T., Sato,H., Watanabe,Y., Itoh,S., Ohta,M. and Kozono,T.
    Crystal structure of human factor VIIa/tissue factor in complex with peptide mimetic inhibitor
    Biochem Biophys Res Commun324, 1227-1233. PubMed  Europe PubMed DOI  S
    13. 2002
  13. [YEAR:15-1-2002]Perera,L., Darden,T.A. and Pedersen,L.G.
    Predicted solution structure of zymogen human coagulation FVII
    J Comput Chem23, 35-47. PubMed  Europe PubMed DOI  S
  14. [YEAR:20-9-2002]Sichler,K., Banner,D.W., D'arcy,A., Hopfner,K.P., Huber,R., Bode,W., Kresse,G.B., Kopetzki,E. and Brandstetter,H.
    Crystal structures of uninhibited factor VIIa link its cofactor and substrate-assisted activation to specific interactions
    J Mol Biol322, 591-603. PubMed  Europe PubMed DOI  S  I
    15. 2001
  15. Eigenbrot,C., Kirchhofer,D., Dennis,M.S., Santell,L., Lazarus,R.A., Stamos,J. and Ultsch,M.H.
    The factor VII zymogen structure reveals reregistration of beta strands during activation
    Structure9, 627-636. PubMed  Europe PubMed DOI  S
    16. 1999
  16. Pike,A.C., Brzozowski,A.M., Roberts,S.M., Olsen,O.H. and Persson,E.
    Structure of human factor VIIa and its implications for the triggering of blood coagulation
    Proc Natl Acad Sci U S A96, 8925-8930. PubMed  Europe PubMed DOI  S
    17. 1996
  17. Banner,D.W., D'arcy,A., Chene,C., Winkler,F.K., Guha,A., Konigsberg,W.H., Nemerson,Y. and Kirchhofer,D.
    The crystal structure of the complex of blood coagulation factor VIIa with soluble tissue factor
    Nature380, 41-46. PubMed  Europe PubMed DOI  S

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