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Literature for peptidase S01.153: elastase-1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

(References are filtered for relevance to Structure. To remove the filter click here. See explanation.)

    2009
  1. Tamada,T., Kinoshita,T., Kurihara,K., Adachi,M., Ohhara,T., Imai,K., Kuroki,R. and Tada,T.
    Combined high-resolution neutron and X-ray analysis of inhibited elastase confirms the active-site oxyanion hole but rules against a low-barrier hydrogen bond
    J Am Chem Soc131, 11033-11040. PubMed  Europe PubMed DOI  S
    2. 2006
  2. Dementiev,A., Dobo,J. and Gettins,P.G.
    Active site distortion is sufficient for proteinase inhibition by serpins: structure of the covalent complex of alpha1-proteinase inhibitor with porcine pancreatic elastase
    J Biol Chem281, 3452-3457. PubMed  Europe PubMed DOI  S
  3. Ding,X., Rasmussen,B.F., Petsko,G.A. and Ringe,D.
    Direct crystallographic observation of an acyl-enzyme intermediate in the elastase-catalyzed hydrolysis of a peptidyl ester substrate: exploiting the "glass transition" in protein dynamics
    Bioorg Chem34, 410-423. PubMed  Europe PubMed DOI  S
  4. [YEAR:1-7-2006]Kinoshita,T., Yamaguchi,A. and Tada,T.
    Tris(hydroxymethyl)aminomethane induces conformational change and crystal-packing contraction of porcine pancreatic elastase
    Acta Crystallograph Sect F Struct Biol Cryst Commun62, 623-626. PubMed  Europe PubMed DOI  S
    5. 2004
  5. [YEAR:1-1-2004]Koizumi,M., Muratani,E., Fujii,K. and Takimoto-Kamimura,M.
    Crystal structure of the complex of porcine pancreatic elastase with TEI-8362
    J Synchrotron Radiat11, 101-104. PubMed  Europe PubMed DOI  S  I
    6. 2003
  6. Ay,J., Hilpert,K., Krauss,N., Schneider-Mergener,J. and Hohne,W.
    Structure of a hybrid squash inhibitor in complex with porcine pancreatic elastase at 1.8 A resolution
    Acta Crystallogr D Biol Crystallogr59, 247-254. PubMed  Europe PubMed DOI  S
  7. [YEAR:6-1-2003]Kinoshita,T., Nakanishi,I., Sato,A. and Tada,T.
    True interaction mode of porcine pancreatic elastase with FR136706, a potent peptidyl inhibitor
    Bioorg Med Chem Lett13, 21-24. PubMed  Europe PubMed DOI  S  I
  8. Matern,U., Schleberger,C., Jelakovic,S., Weckesser,J. and Schulz,G.E.
    Binding structure of elastase inhibitor scyptolin A
    Chem Biol10, 997-1001. PubMed  Europe PubMed DOI  S  I
    9. 2002
  9. [YEAR:14-6-2002]Katona,G., Wilmouth,R.C., Wright,P.A., Berglund,G.I., Hajdu,J., Neutze,R. and Schofield,C.J.
    X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution
    J Biol Chem277, 21962-21970. PubMed  Europe PubMed DOI  S
  10. Weiss,M.S., Panjikar,S., Nowak,E. and Tucker,P.A.
    Metal binding to porcine pancreatic elastase: calcium or not calcium
    Acta Crystallogr D Biol Crystallogr58, 1407-1412. PubMed  Europe PubMed DOI  S
    11. 2001
  11. Wright,P.A., Wilmouth,R.C., Clifton,I.J. and Schofield,C.J.
    Kinetic and crystallographic analysis of complexes formed between elastase and peptides from beta-casein
    Eur J Biochem268, 2969-2974. PubMed  Europe PubMed  S
    12. 2000
  12. [YEAR:15-4-2000]Nakanishi,I., Kinoshita,T., Sato,A. and Tada,T.
    Structure of porcine pancreatic elastase complexed with FR901277, a novel macrocyclic inhibitor of elastases, at 1.6 A resolution
    Biopolymers53, 434-445. PubMed  Europe PubMed DOI  S  I
  13. Wurtele,M., Hahn,M., Hilpert,K. and Hohne,W.
    Atomic resolution structure of native porcine pancreatic elastase at 1.1 A
    Acta Crystallogr D Biol Crystallogr56, 520-523. PubMed  Europe PubMed DOI  S
    14. 1999
  14. [YEAR:27-8-1999]Taylor,P., Anderson,V., Dowden,J., Flitsch,S.L., Turner,N.J., Loughran,K. and Walkinshaw,M.D.
    Novel mechanism of inhibition of elastase by beta-lactams is defined by two inhibitor crystal complexes
    J Biol Chem274, 24901-24905. PubMed  Europe PubMed DOI  S  I
    15. 1996
  15. [YEAR:10-9-1996]Tsunemi,M., Matsuura,Y., Sakakibara,S. and Katsube,Y.
    Crystal structure of an elastase-specific inhibitor elafin complexed with porcine pancreatic elastase determined at 1.9 A resolution
    Biochemistry35, 11570-11576. PubMed  Europe PubMed DOI  S
    16. 1995
  16. Berglund,G.I., Smalas,A.O., Hansen,L.K. and Willassen,N.P.
    Crystallization and preliminary X-ray crystallographic studies of native elastase from North Atlantic salmon (Salmo salar)
    Acta Crystallogr D Biol Crystallogr51, 393-394. PubMed  Europe PubMed DOI  S
  17. Berglund,G.I., Willassen,N.P., Hordvik,A. and Smalas,A.O.
    Structure of native pancreatic elastase from North Atlantic salmon at 1.61 A resolution
    Acta Crystallogr D Biol Crystallogr51, 925-937. PubMed  Europe PubMed DOI  S
  18. Peisach,E., Casebier,D., Gallion,S.L., Furth,P., Petsko,G.A., Hogan,J.C., Jr. and Ringe,D.
    Interaction of a peptidomimetic aminimide inhibitor with elastase
    Science269, 66-69. PubMed  Europe PubMed  S  I
    19. 1994
  19. Mattos,C., Rasmussen,B., Ding,X., Petsko,G.A. and Ringe,D.
    Analogous inhibitors of elastase do not always bind analogously
    Nat Struct Biol1, 55-58. PubMed  Europe PubMed  S  I
    20. 1992
  20. Edwards,P.D., Meyer,E.F., Jr., Vijayalakshmi,J., Tuthill,P.A., Andisik,D.A., Gomes,B. and Strimpler,A.
    Design, synthesis, and kinetic evaluation of a unique class of elastase inhibitors, the peptidyl alpha-ketobenzoxazoles, and the X-ray crystal structure of the covalent complex between porcine pancreatic elastase and Ac-Ala-Pro-Val-2-benzoxazole
    J Am Chem Soc114, 1854-1863.  S  I
  21. Hernandez,M.A., Powers,J.C., Glinski,J., Oleksyszyn,J., Vijayalakshmi,J. and Meyer,E.F., Jr.
    Effect of the 7-amino substituent on the inhibitory potency of mechanism-based isocoumarin inhibitors for porcine pancreatic and human neutrophil elastases: A 1.85-A X-ray structure of the complex between porcine pancreatic elastase and 7-[(N- tosylphenylalanyl)amino]-4-chloro-3-methoxyisocoumarin
    J Med Chem35, 1121-1129. PubMed  Europe PubMed  S  I
    22. 1990
  22. de la Sierra,I.L., Papamichael,E., Sakarellos,C., Dimicoli,J.L. and Prange,T.
    Interaction of the peptide CF3-Leu-Ala-NH-C6H4-CF3 (TFLA) with porcine pancreatic elastase. X-ray studies at 1.8 A
    J Mol Recognit3, 36-44. PubMed  Europe PubMed DOI  S  I
  23. Powers,J.C., Oleksyszyn,J., Narasimhan,S.L. and Kam,C.M.
    Reaction of porcine pancreatic elastase with 7-substituted 3- alkoxy-4-chloroisocoumarins: design of potent inhibitors using the crystal structure of the complex formed with 4-chloro-3- ethoxy-7-guanidinoisocoumarin
    Biochemistry29, 3108-3118. PubMed  Europe PubMed  S  I
    24. 1989
  24. Bode,W., Meyer,E., Jr. and Powers,J.C.
    Human leukocyte and porcine pancreatic elastase: X-ray crystal structures, mechanism, substrate specificity, and mechanism-based inhibitors
    Biochemistry28, 1951-1963. PubMed  Europe PubMed  S  I
  25. Takahashi,L.H., Radhakrishnan,R., Rosenfield,R.E., Jr., Meyer,E.F. and Trainor,D.A.
    Crystal structure of the covalent complex formed by a peptidyl alpha, alpha-difluoro-beta-keto amide with porcine pancreatic elastase at 1.78- _ resolution
    J Am Chem Soc111, 3368-3374.  S
  26. Takahashi,L.H., Radhakrishnan,R., Rosenfield,R.E., Jr. and Meyer,E.F., Jr.
    Crystallographic analysis of the inhibition of porcine pancreatic elastase by a peptidyl boronic acid: structure of a reaction intermediate
    Biochemistry28, 7610-7617. PubMed  Europe PubMed  S  I
    27. 1988
  27. Meyer,E., Cole,G., Radhakrishnan,R. and Epp,O.
    Structure of native porcine pancreatic elastase at 1.65 A resolutions
    Acta Crystallogr B44, 26-38. PubMed  Europe PubMed DOI  S
  28. Meyer,E.F., Jr., Clore,G.M., Gronenborn,A.M. and Hansen,H.A.
    Analysis of an enzyme-substrate complex by X-ray crystallography and transferred nuclear Overhauser enhancement measurements: porcine pancreatic elastase and a hexapeptide
    Biochemistry27, 725-730. PubMed  Europe PubMed  S
    29. 1987
  29. [YEAR:7-5-1987]Navia,M.A., Springer,J.P., Lin,T.Y., Williams,H.R., Firestone,R.A., Pisano,J.M., Doherty,J.B., Finke,P.E. and Hoogsteen,K.
    Crystallographic study of a beta-lactam inhibitor complex with elastase at 1.84 A resolution
    Nature327, 79-82. PubMed  Europe PubMed DOI  S  I
  30. Radhakrishnan,R., Presta,L.G., Meyer,E.F., Jr. and Wildonger,R.
    Crystal structures of the complex of porcine pancreatic elastase with two valine-derived benzoxazinone inhibitors
    J Mol Biol198, 417-424. PubMed  Europe PubMed  S  I
    31. 1986
  31. Clore,G.M., Gronenborn,A.M., Carlson,G. and Meyer,E.F.
    Stereochemistry of binding of the tetrapeptide acetyl-Pro-Ala-Pro-Tyr-NH2 to porcine pancreatic elastase. Combined use of two-dimensional transferred nuclear Overhauser enhancement measurements, restrained molecular dynamics, X-ray crystallography and molecular modelling
    J Mol Biol190, 259-267. PubMed  Europe PubMed  S  I
  32. Meyer,E.F., Jr., Radhakrishnan,R., Cole,G.M. and Presta,L.G.
    Structure of the product complex of acetyl-Ala-Pro-Ala with porcine pancreatic elastase at 1.65 A resolution
    J Mol Biol189, 533-539. PubMed  Europe PubMed  S
    33. 1978
  33. Sawyer,L., Shotton,D.M., Campbell,J.W., Wendell,P.L., Muirhead,H. and Watson,H.C.
    The atomic structure of crystalline porcine pancreatic elastase at 2.5 A resolution: comparisons with the structure of alpha-chymotrypsin
    J Mol Biol118, 137-208. PubMed  Europe PubMed  S
    34. 1973
  34. Sawyer,L., Shotton,D.M.W. and Watson,H.C.
    Atomic coordinates for tosyl-elastase
    Biochem Biophys Res Commun53, 944-951. PubMed  Europe PubMed  S
    35. 1970
  35. Shotton,D.M. and Watson,H.C.
    The three-dimensional structure of crystalline porcine pancreatic elastase
    Philos Trans R Soc Lond B Biol Sci257, 111-118. PubMed  Europe PubMed  S
  36. [YEAR:28-2-1970]Watson,H.C., Shotton,D.M., Cox,J.M. and Muirhead,H.
    Three-dimensional Fourier synthesis of tosyl-elastase at 3.5A resolution
    Nature225, 806-811. PubMed  Europe PubMed DOI  S  I

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