Literature for peptidase S08.039: PCSK9 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2018
  1. Chorba,J.S., Galvan,A.M. and Shokat,K.M.
    Stepwise processing analyses of the single-turnover PCSK9 protease reveal its substrate sequence specificity and link clinical genotype to lipid phenotype
    J Biol Chem293, 1875-1886. PubMed  Europe PubMed DOI  P
  2. 2012
  3. Benjannet,S., Hamelin,J., Chretien,M. and Seidah,N.G.
    Loss- and gain-of-function PCSK9 variants: cleavage specificity, dominant negative effects, and low density lipoprotein receptor (LDLR) degradation
    J Biol Chem287, 33745-33755. PubMed  Europe PubMed DOI  M  P