Literature for peptidase S01.140: chymase (Homo sapiens-type)

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Pharma

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    2019
  1. Fu,Z., Akula,S., Thorpe,M., Chahal,G., de Garavilla,L., Kervinen,J. and Hellman,L.
    Extended cleavage specificity of sheep mast cell protease-2: a classical chymase with preference to aromatic P1 substrate residues
    Dev Comp Immunol92, 160-169. PubMed  Europe PubMed DOI  P
  2. Fu,Z., Akula,S., Thorpe,M. and Hellman,L.
    Highly selective cleavage of TH2-promoting cytokines by the human and the mouse mast cell tryptases, indicating a potent negative feedback loop on TH2 immunity
    Int J Mol Sci20, PubMed  Europe PubMed DOI  P
  3. 2017
  4. Fu,Z., Thorpe,M., Alemayehu,R., Roy,A., Kervinen,J., de Garavilla,L., Abrink,M. and Hellman,L.
    Highly selective cleavage of cytokines and chemokines by the human mast cell chymase and neutrophil cathepsin G
    J Immunol198, 1474-1483. PubMed  Europe PubMed DOI  P
  5. 2012
  6. Thorpe,M., Yu,J., Boinapally,V., Ahooghalandari,P., Kervinen,J., Garavilla,L. and Hellman,L.
    Extended cleavage specificity of the mast cell chymase from the crab-eating macaque (Macaca fascicularis): an interesting animal model for the analysis of the function of the human mast cell chymase
    Int Immunol24, 771-782. PubMed  Europe PubMed DOI  P
  7. 2011
  8. Korkmaz,B., Jegot,G., Lau,L.C., Thorpe,M., Pitois,E., Juliano,L., Walls,A.F., Hellman,L. and Gauthier,F.
    Discriminating between the activities of human cathepsin G and chymase using fluorogenic substrates
    FEBS J278, 2635-2646. PubMed  Europe PubMed DOI  A  P
  9. 2010
  10. Gallwitz,M., Enoksson,M., Thorpe,M., Ge,X. and Hellman,L.
    The extended substrate recognition profile of the dog mast cell chymase reveals similarities and differences to the human chymase
    Int Immunol22, 421-431. PubMed  Europe PubMed DOI  P
  11. 2009
  12. Andersson,M.K., Enoksson,M., Gallwitz,M. and Hellman,L.
    The extended substrate specificity of the human mast cell chymase reveals a serine protease with well-defined substrate recognition profile
    Int Immunol21, 95-104. PubMed  Europe PubMed DOI  P
  13. 2008
  14. Caughey,G.H., Beauchamp,J., Schlatter,D., Raymond,W.W., Trivedi,N.N., Banner,D., Mauser,H. and Fingerle,J.
    Guinea pig chymase is leucine-specific: a novel example of functional plasticity in the chymase/granzyme family of serine peptidases
    J Biol Chem283, 13943-13951. PubMed  Europe PubMed DOI  P
  15. Reimer,J.M., Enoksson,M., Samollow,P.B. and Hellman,L.
    Extended substrate specificity of opossum chymase - implications for the origin of mast cell chymases
    Mol Immunol45, 2116-2125. PubMed  Europe PubMed DOI  P
  16. 2007
  17. Hamuro,T., Kido,H., Asada,Y., Hatakeyama,K., Okumura,Y., Kunori,Y., Kamimura,T., Iwanaga,S. and Kamei,S.
    Tissue factor pathway inhibitor is highly susceptible to chymase-mediated proteolysis
    FEBS J274, 3065-3077. PubMed  Europe PubMed DOI  P
  18. 2006
  19. [YEAR:15-12-2006]Omoto,Y., Tokime,K., Yamanaka,K., Habe,K., Morioka,T., Kurokawa,I., Tsutsui,H., Yamanishi,K., Nakanishi,K. and Mizutani,H.
    Human mast cell chymase cleaves pro-IL-18 and generates a novel and biologically active IL-18 fragment
    J Immunol177, 8315-8319. PubMed  Europe PubMed  P
  20. 2003
  21. [YEAR:5-9-2003]Raymond,W.W., Ruggles,S.W., Craik,C.S. and Caughey,G.H.
    Albumin is a substrate of human chymase. Prediction by combinatorial peptide screening and development of a selective inhibitor based on the albumin cleavage site
    J Biol Chem278, 34517-34524. PubMed  Europe PubMed DOI  P
  22. 2002
  23. [YEAR:13-2-2002]Solivan,S., Selwood,T., Wang,Z.M. and Schechter,N.M.
    Evidence for diversity of substrate specificity among members of the chymase family of serine proteases
    FEBS Lett512, 133-138. PubMed  Europe PubMed DOI  P