Literature for peptidase S08.076: PCSK5 peptidase

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Literature Substrates Pharma

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    2015
  1. Sathyamurthy,M., Kim,C.L., Bang,Y.L., Kim,Y.S., Jang,J.W. and Lee,G.M.
    Characterization and expression of proprotein convertases in CHO cells: efficient proteolytic maturation of human bone morphogenetic protein-7
    Biotechnol Bioeng112, 560-568. PubMed  Europe PubMed DOI  I
  2. 2014
  3. Ho,H., Li,Y. and Nie,G.
    Inhibition of embryo implantation in mice through vaginal administration of a proprotein convertase 6 inhibitor
    Reprod Biol14, 155-159. PubMed  Europe PubMed DOI  I
  4. 2013
  5. Ho,H., Singh,H., Heng,S., Nero,T.L., Paule,S., Parker,M.W., Johnson,A.T., Jiao,G.S. and Nie,G.
    Small molecule proprotein convertase inhibitors for inhibition of embryo implantation
    PLoS ONE8, e81380-e81380. PubMed  Europe PubMed DOI  I
  6. 2012
  7. Aljofan,M., Singh,H., Ho,H., Xie,S., Zhu,Y., Sun,Z., Guo,X., Wang,J. and Nie,G.
    Inhibition of proprotein convertase 5/6 activity: potential for nonhormonal women-centered contraception
    Contraception85, 602-610. PubMed  Europe PubMed DOI  T  I
  8. Ho,H., Nero,T.L., Singh,H., Parker,M.W. and Nie,G.
    PEGylation of a proprotein convertase peptide inhibitor for vaginal route of drug delivery: in vitro bioactivity, stability and in vivo pharmacokinetics
    Peptides38, 266-274. PubMed  Europe PubMed DOI  I
  9. 2010
  10. Khatib,A.M., Lahlil,R., Scamuffa,N., Akimenko,M.A., Ernest,S., Lomri,A., Lalou,C., Seidah,N.G., Villoutreix,B.O., Calvo,F. and Siegfried,G.
    Zebrafish ProVEGF-C expression, proteolytic processing and inhibitory effect of unprocessed ProVEGF-C during fin regeneration
    PLoS ONE5, e11438-e11438. PubMed  Europe PubMed DOI  I
  11. Tian,S. and Jianhua,W.
    Comparative study of the binding pockets of mammalian proprotein convertases and its implications for the design of specific small molecule inhibitors
    Int J Biol Sci6, 89-95. PubMed  Europe PubMed  P  I
  12. 2007
  13. Fugere,M., Appel,J., Houghten,R.A., Lindberg,I. and Day,R.
    Short polybasic peptide sequences are potent inhibitors of PC5/6 and PC7: use of positional scanning-synthetic peptide combinatorial libraries as a tool for the optimization of inhibitory sequences
    Mol Pharmacol71, 323-332. PubMed  Europe PubMed DOI  I
  14. 2002
  15. Fugere,M. and Day,R.
    Inhibitors of the subtilase-like pro-protein convertases (SPCs)
    Curr Pharm Des8, 549-562. PubMed  Europe PubMed DOI  V  I