Summary for peptidase C03.011: Coxsackievirus-type picornain 3C

Summary Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors

 

Names
MEROPS NameCoxsackievirus-type picornain 3C
Other namespicornain 3C (Coxsackievirus)
Domain architecture
MEROPS Classification
Classification Clan PA >> Subclan PA(C) >> Family C3 >> Subfamily A >> C03.011
HolotypeCoxsackievirus-type picornain 3C (human coxsackievirus B3), Uniprot accession P03313 (peptidase unit: 1541-1723), MERNUM MER0000751
History Identifier created: MEROPS 3.02 (25 June 1998)
Activity
Catalytic typeCysteine
NC-IUBMBNot yet included in IUBMB recommendations.
Proteolytic eventsCutDB database (1 cleavage)
PhysiologyViral polyprotein processing in replication.
Cleavage site specificity Explanations of how to interpret the following cleavage site sequence logo and specificity matrix can be found here.
Cleavage patternA/L/Fyl/QScissile bondG/P/P/V (based on 10 cleavages)
weblogo
Specificity matrix
 
Amino acid P4 P3 P2 P1 P1' P2' P3' P4'
Gly 0 1 0 0 10 1 0 0
Pro 0 0 0 0 0 7 6 1
Ala 9 0 0 0 0 0 0 0
Val 1 0 0 0 0 0 0 6
Leu 0 8 1 0 0 0 0 0
Ile 0 0 0 0 0 0 0 0
Met 0 0 0 0 0 0 0 0
Phe 0 0 7 0 0 0 0 0
Tyr 0 0 2 0 0 1 0 0
Trp 0 0 0 0 0 0 0 0
Ser 0 0 0 0 0 0 1 0
Thr 0 1 0 0 0 0 0 0
Cys 0 0 0 0 0 0 0 0
Asn 0 0 0 0 0 0 0 0
Gln 0 0 0 10 0 0 0 0
Asp 0 0 0 0 0 0 0 0
Glu 0 0 0 0 0 0 0 0
Lys 0 0 0 0 0 0 0 0
Arg 0 0 0 0 0 0 0 0
His 0 0 0 0 0 0 0 0