Activity |
Catalytic type | Serine |
Peplist | Included in the Peplist with identifier PL00333 |
NC-IUBMB | Subclass 3.4 (Peptidases) >> Sub-subclass 3.4.21 (Serine endopeptidases) >> Peptidase 3.4.21.107
|
Enzymology | BRENDA database |
Physiology | A heat-shock protein in E. coli that is required for growth at elevated temperatures, probably funtioning in the degradation of unfolded proteins. |
Pharmaceutical relevance | Reported to be essential for the virulence of pathogenic bacteria including Salmonella enterica serovar typhimurium, Yersia entericolitica and Streptococcus pyogenes (Pallen & Wren, 1997). |
Pathways |
KEGG | Two-component system |
Other databases
| PANTHER | http://www.pantherdb.org/panther/familyList.do?searchType=basic&fieldName=all&listType=6&fieldValue=PTHR22939:SF109 |
Cleavage site specificity |
Explanations of how to interpret the
following cleavage site sequence logo and specificity matrix can be found here. |
Cleavage pattern | -/-/-/V-/-/-/- (based on 16 cleavages) |