Inhibitors for peptidase M13.002: endothelin-converting enzyme 1

Summary Gene structure Alignment Tree Sequences Sequence features Distribution Structure Literature Substrates Inhibitors Pharma
MERID Inhibitor Inhibitor name Ki Conditions Reference
CGS 26303 Jeng et al., 2000
CGS 34043 De Lombaert et al., 2000
CGS 35066 Jeng et al., 2000
FR901533 89 nM Tsurumi et al., 1995
SLV306 Dickstein et al., 2004
SM-19712  
CGS 30084 Fink et al., 2000
WS75624 A Tsurumi et al., 1995
WS75624 B Tsurumi et al., 1995
CGS 26393 Dai et al., 2010
SLV338 Wengenmayer et al., 2011
R-569 Martinez-Miguel et al., 2013
phosphorus-containing inhibitors of metallopeptidases FII  
phosphoramidon Ahn et al., 1998
phosphoramidon Schulz et al., 2009
thiorphan weak inhibition Thomas et al., 2005
CGS 35601 Battistini et al., 2005
EDTA Ohnaka et al., 1993
1,10->phenanthroline Ohnaka et al., 1993
candoxatril Danilewicz et al., 1989