Alignment for family S8

        11                               12                                               13                                                                                      14                                                                                                                                                                 15                                                                                                                                                      16                                                                                                                                                                                                                                                                                                 17                                      18                                                                          19                 20                                 21                                                                                           22                                                                                    23                                                                  24                          25                                                                                                                   26                             27                                                                                                                                                                               28                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                       29                                                30                                                                                                                                                                                                                         31                                                                                                                                 32                              33                                                                  34                                                                                              35                                                                                                                                     36                       37        3
     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                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                   #                                                                                                                                                                                                                                                                                                                                                  
                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                                          
   1 YLKEAPYGINASYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--DHEDLVNQKIE-------------------LISGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------KVGNIGI--APK-A--KVKVV---SQ-----------------------IRGDG----SYNTADA-------------------------------------I--------INA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VQPAIFD-----------AIRA---------GTDK----GI-----I--------------------------------------------------------------------------------------V---------------IEAGA-N-------GTNDLDQ--FRDKNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---IG--A--------ASSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TRAEPNGIT----------KN---LYTTGF-SG------TSSASPIIA----G---------------------------A------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   1
   2 YLKEAPYGINASYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--DHEDLVNQKIE-------------------LISGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------KVGNIGI--APK-A--KVKVV---SQ-----------------------IRGDG----SYNTADA-------------------------------------I--------INA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VQPAIFD-----------AIRA---------GTDK----GI-----I--------------------------------------------------------------------------------------V---------------IEAGA-N-------GTNDLDQ--FRDKNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---IG--A--------ASSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TRAEPNGIT----------KN---LYTTGF-SG------TSSASPIIA----G---------------------------A------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   2
   3 YLKEAPYGINASYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--DHEDLVNQKIE-------------------LISGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------KVGNIGI--APK-A--KVKVV---SQ-----------------------IRGDG----SYNTADA-------------------------------------I--------INA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VQPAIFD-----------AIRA---------GTDK----GI-----I--------------------------------------------------------------------------------------V---------------IEAGA-N-------GTNDLDQ--FRDKNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---IG--A--------ASSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TRAEPNRIT----------KN---LYTTGF-SG------TSSASPIIA----G---------------------------A------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   3
   4 YLKEAPYGINASYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--DHEDLVNQKIE-------------------LISGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------KVGNIGI--APK-A--KVKVV---SQ-----------------------IRGDG----SYNTADA-------------------------------------I--------INA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VQPAIFD-----------AIRA---------GTDK----GI-----I--------------------------------------------------------------------------------------V---------------IEAGA-N-------GSIDLDQ--FRDKNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---IG--A--------ASSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TRAEPNRIT----------KN---LYTTGF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGVAKEHLGRPYKPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SN---------------------------------------------------------------------------------------------------------------------------------------   4
   5 YFKEAPYGINASYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--DHEDLVNQKVE-------------------LISGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------KVGNIGI--APK-A--KVKVV---SQ-----------------------IRGDG----SYNTADA-------------------------------------I--------IDA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----I--------------------------------------------------------------------------------------V---------------IEAGA-N-------GSNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGT-------------------------------IM---IG--A--------ASSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TRAEPNRIT----------KN---LYTTGF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGVAKEHLGRPYKPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGTKSQNPLTD--------------------------------------------------------------------------------------------------------------------------   5
   6 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILTRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   6
   7 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GVDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------   7
   8 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNQNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GADK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSPYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGT----------------------------------------------------------------------------------------------------------------------------------   8
   9 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNQNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GADK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSPYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGT----------------------------------------------------------------------------------------------------------------------------------   9
  10 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GADK----GI-----I--------------------------------------------------------------------------------------L---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  10
  11 ---------NASHAWSIKGG-------------------------------------DGK--------------------------D-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHQ-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  11
  12 ---------NASHAWSIKGG-------------------------------------DGK--------------------------D-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHQ-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  12
  13 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APR-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGEK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTATF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSPYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGT----------------------------------------------------------------------------------------------------------------------------------  13
  14 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APR-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSSYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  14
  15 YLEAAPKGINASYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APR-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGEK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSPYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGT----------------------------------------------------------------------------------------------------------------------------------  15
  16 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APR-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQAGDILLLEAQ-AS-------------------YD-GYGEK-YL------PVE-----VHPDIFD-----------AIRV---------GTDK----GI-----M--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNN----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSPYTPAEL-----------------------------------------------------------------------------------------------------------RNIL-------SNPNTGT----------------------------------------------------------------------------------------------------------------------------------  16
  17 YLEAAPKGINASHAWSIKGG-------------------------------------DGK--------------------------D-T--TF------------------------------------VDMEYGWLL--NHEDLVNKNIK-------------------LMSGQNISQ------H--------------------------------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------QIGNIGI--APK-A--NVKVI---SQ-----------------------IRDNG----IYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VH-----------------------------------------------NLQTGDILLLEAQ-AS-------------------YD-GYGDK-YL------PVE-----VHPDIFD-----------AIRV---------GADK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GSNDLDN--FKDRNGKKILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------GSSTVPHK-RLWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-L----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TSANPSQNT----------TN---LYTSTF-SG------TSSASPIIA----G---------------------------A------------------ATSI----QGIAKEHRGSP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  17
  18 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQKIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----NYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYF------PVE-----VKPDIFD-----------AIRM---------GTNK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------SDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFI----------TN---LYTSSF-AG------TSSASPIIA----G---------------------------A------------------AASI----QGIVKNNQGRVYTPRQL-----------------------------------------------------------------------------------------------------------RAIL-------SDSSTGT----------------------------------------------------------------------------------------------------------------------------------  18
  19 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--SHEDLVNQKIE-------------------LMSGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----NYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYF------PVE-----VKPDIFD-----------AIRM---------GTNK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFI----------TN---LYTSSF-AG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  19
  20 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLL--SHEDLVNQKIE-------------------LMSGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----NYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQVGDILLLEAQ-AT-------------------YD-GYGDKNYF------PVE-----VKPDIFD-----------AIRM---------GTNK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFI----------TN---LYTSSF-AG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  20
  21 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQKIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GTNK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGS-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFT----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  21
  22 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--NHEDLVNQNIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YE-GYGDKNYL------PVE-----VKPDIFD-----------AIRL---------GTNK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGS-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFT----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  22
  23 YLEPAPLGINAPYAWSIKGG-------------------------------------DGN--------------------------G-T--TF------------------------------------VDMEYGWLF--THEDLVNQNIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYSTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRL---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RLYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  23
  24 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQKIA-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----NYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRL---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFT----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKHN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  24
  25 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--NHEDLVNQNIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDIFLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRL---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-GG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  25
  26 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQNIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  26
  27 YLEPAPLGINAPYAWSIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQKIE-------------------LMSGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPREFM----------TN---LYTSSF-GG------TSSASPIIA----G---------------------------A------------------AASI----QGIVKNNQGKVYTPSQL-----------------------------------------------------------------------------------------------------------RDIL-------SDSSTGT----------------------------------------------------------------------------------------------------------------------------------  27
  28 YLEPAPLGINAPYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQNIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NIQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  28
  29 YLEPAPLGINAPYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--THEDLVNQKIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIVKNNQGKVYTPSQL-----------------------------------------------------------------------------------------------------------RDIL-------SDSSTGT----------------------------------------------------------------------------------------------------------------------------------  29
  30 YLEPAPLGINAPYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--THEDLVNQKIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  30
  31 YLEPAPLGINAPYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--THEDLVNQKIE-------------------LISGQNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HMQAGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRI---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FRDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPSEFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  31
  32 YLEPAPLGINAPYAWGIKGG-------------------------------------DGK--------------------------G-T--TF------------------------------------VDMEYGWLF--SHEDLVNQNIE-------------------LISGLNKSE------H--------------------------------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TS-V-----------------------LGIVS----AEDN------------------------------------------------------------------NIGGIGI--APK-A--KVKVV---SQ-----------------------IRDNG----RYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------NMQVGDILLLEAQ-AT-------------------YD-GYGDKNYL------PVE-----VKPDIFD-----------AIRM---------GANK----GI-----I--------------------------------------------------------------------------------------I---------------IEAGA-N-------GGNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGA-------------------------------IM---VG--A--------ASARVPHK-RSYF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-V----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------NA--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TDAKPREFM----------TN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------AASI----QGIAKNN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  32
  33 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLVHKNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTTSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  33
  34 YLEAAPYGINAPFAWGVQGG-------------------------------------NGK--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------DVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDR--FKDRKGKQVLNRSS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------LN---LYTSNF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSITKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  34
  35 ---------NASFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGINIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  35
  36 ---------NASFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGINIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  36
  37 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------D-V--TF------------------------------------VDMEYGWLL--NHEDLVHRNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRIA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  37
  38 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------D-V--TF------------------------------------VDMEYGWLL--NHEDLVHRNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  38
  39 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------D-V--TF------------------------------------VDMEYGWLL--NHEDLVHRNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  39
  40 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLAHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EIGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------IN---LYTPSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNKNTGT----------------------------------------------------------------------------------------------------------------------------------  40
  41 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------D-I--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------HLNAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------II---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------ET--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  41
  42 YLEAAPYGINAPFAWEIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  42
  43 -------------------G-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNINQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKEHLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGT----------------------------------------------------------------------------------------------------------------------------------  43
  44 ---------NTPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENVGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  44
  45 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQKIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDE--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  45
  46 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQKIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  46
  47 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQKIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDE--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  47
  48 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  48
  49 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNINQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------AN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  49
  50 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNINQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  50
  51 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNINQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDSYADK-------------------------------------------------------------------------------------------------------------------------  51
  52 YLEAAPYGINAPFAWGVQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQNIE-------------------LMSGRNINQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  52
  53 YLEAAPYGINAPFAWGIQGG-------------------------------------NGN--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLLHQKIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADG-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GI-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRKGKQVLNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SNQSTGTKSKDPYADK-------------------------------------------------------------------------------------------------------------------------  53
  54 YLEAAPYGINAPFAWEVQGG-------------------------------------KGS--------------------------G-I--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGINIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------VN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------S----------------------------------------------------------------------------------------------------------------------------------------  54
  55 YLEAAPSGINAPFAWGVRGG-------------------------------------NGS--------------------------D-V--TF------------------------------------VDMEYGWLL--NHEDLVHQNIE-------------------LMSGRNIDQ------H--------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LGIVS----SEDN------------------------------------------------------------------EVGNIGI--APK-A--KAKVI---SQ-----------------------IRDNG----QYNTADA-------------------------------------I--------LSA-----------------------------------------------------------------------------IN-----------------------------------------------QLEAGDVLLLEAQ-AS-------------------FD-GYGDK-YL------PVE-----VQPDIFD-----------AIRA---------GTDK----GV-----V--------------------------------------------------------------------------------------I---------------IEAGA-N-------GWNDLDQ--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------KDFKDSGA-------------------------------IM---VG--A--------GSSSFPHE-RMWF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EN--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------TTAEQSRSA----------VN---LYTSSF-SG------TSSASPIIA----G---------------------------A------------------ATLV----QSIAKENLGQPYRPSEL-----------------------------------------------------------------------------------------------------------RAIL-------SN---------------------------------------------------------------------------------------------------------------------------------------  55
  56 YLEEAPLGINAPYAWGIKGG-------------------------------------NGQ--------------------------G-A--TF------------------------------------VDLEEGWLL--NHEDLVGQNIE-------------------FMSGK-MSN------D--------------------------------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-V-----------------------LGVVS----AADN------------------------------------------------------------------GIGNIGI--APK-A--KAKVI---SV-----------------------IRDNG----RIDVRDA-------------------------------------I--------LSA-----------------------------------------------------------------------------VD-----------------------------------------------SLQAGDVLLIEES-FK-------------------YD-GYGDD-PL------PVE-----VYPSIFN-----------AIRK---------GTDK----GI-----I--------------------------------------------------------------------------------------I---------------VEAAG-N-------GGIDLDE--FKDRNGKQILNRNS------------------------------------------------------------------------------------------------------------------------------------------PDFKDSGS-------------------------------II---VG--A--------STARVPHK-RLAF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSR-I----------------------------------------------------------------------D-----V------Y-----------------G-----W-------------G-----------------EY--------------------------------V------------------------------------------------------------------DT--------------------------------------------------------------------------------------------------------------------LDTYQNQNSKGQKITDQNIIN---RYTPNF-RG------TSSASPIIA----G---------------------------A------------------AVSI----QGIAKEHLGKAYSPKEL-----------------------------------------------------------------------------------------------------------RAIL-------SNPNTGTKSNNPSSD--------------------------------------------------------------------------------------------------------------------------  56
  57 YLNAAPAGIDARHAWNFPGG-------------------------------------KGN--------------------------G-V--NI------------------------------------VDIEGAWRF--SHEDLRENQGG-------------------VIAGTPSSD------L-------------G---------W--------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TA-V-----------------------IGEIS----GDEN------------------------------------------------------------------GVGVTGI--SPN-A--KIHAI---SV-----------------------FGQN------QTSSNA-------------------------------------I--------LQA-----------------------------------------------------------------------------AN-----------------------------------------------ALGAGDIILIELH-APGPRFN-------------FQD-RPDQKGYI------AME-----WWKDDFE-----------AIRF---------ATAK----GI-----I--------------------------------------------------------------------------------------V---------------VGAAG-N-------GAEDLDDPIYENR-----FNRSQ---------------------------------------------------------------------------------------------------------------------------------------------RDSGA-------------------------------IL---VG--AGAPPPGTHGSDHGPDRSRLPF---------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GSI-V----------------------------------------------------------------------D-----T------Q-----------------A-----W-------------G-----------------RE--------------------------------V------------------------------------------------------------------TT--------------------------------------------------------------------------------------------------------------------TGYSDLQGG----------VNEDSWYTDRF-SG------TSSASPIVV----G---------------------------T------------------IACL----QGIVKARGQSPLTPIRV-----------------------------------------------------------------------------------------------------------RNML-------RNSGSPQQDAQTRPKTQRIGN--------------------------------------------------------------------------------------------------------------------  57
  58 ---------------------------LNSGQDGFSARGGIAGNDLNLWWAHRTG-VLGQ--------------------------G-V--NV--------------A--------------------VVD---------------------------D--------------GLAI-A------H-------------P---------D--------------------------------LADNVRPGSKNVVTGSDDPTPTDPDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TS-V-----------------------SGIIAAVDNAIGTK----------------------------------------------------------------------GI--APR-A--QLQGF---NLLDDNSQQL-QKDWLYALGDSN---------------ASR---------------------------------------------------------------------------DN------------------------------------------------------RV-----------------------------------------FNQSYGMSVVDPRS-----------------------------------------------------------------ANSLDQSQLDRLFEQQTLKAQGA-----A--------------------------------------------------------------------------------------Y---------------IKAAG-NGFNK--IAAGGYVLNRTGNG----------------------------------------------------------------------------------------------------------------------------------------------------PKLPFENSNLDPSNSNFWNLVVSALNADGVRSSYSS--------VG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--NIFLSATGGEYGTDTP----------------------------------------------------------------------AMVTTDL------------------------------P-------------G-----------------CD---------------------------------------------------------------------------------------------------MG----------------------------------------------------------------------------------------------------------------------YNRTDDPST-NRLHGNSQLDASCDYNGVMNG------TSSATPSTS----G---------------------------A------------------MALL----MS------------AYPDLS----------------------------------------------------------------------------------V------------------RDLRDLL-------ARS----------------------------------------------------------------------ATRVDAKHQPVMVSYTSSTGKVRDVKGLEGWERNAAGMWFSPTYGFGLIDVNKALE--------  58
  59 -------------------------------------QIQADAVQ-------ATG-NKGK--------------------------G-I--KI--------------G--------------------IID---------------------------G--------------GVDY-T------R-------------E---------P--------------------------------LGG--------------CFGSGC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------AGGYD---FVGDNYDGSNDPVPDNDPYDNCY--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-I-----------------------SGIIG----AN-QN-------------------------------IY------------GAV----------------------GV--APE-A--SLYVY---RV---FGCN----------G-AA--S------------DDI-------------------------------------V--------LAA--------------M-----------QK---AY--------------------D-----D------D----------M----DV-----------------------------------------INLSLG---------------E--------------------PS--------------------------GWTESTLSVFASR---------VVAK----GT-----V--------------------------------------------------------------------------------------V---------------TVSAG-NQ--------GQ---------V-----GGFYSSS---------------------------------------------------------------------------------------------------------------------------------------P-AAGK-G---------------------------V---IN---VG--S------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSSIYPAHL---------------------------------------------------------ATVSTGY----GPIAYYN--TA-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TT-SYF-----S--E--------I-GPT-N----------------------------------------------------------------------D-----LYFAPSVL-----------------A-----P-------------G-----------------TN--------------------------------V------------------------------------------------------------------VG-VMP---------------------------------------------------------------------------------------------------------------------TTFYNW-TI----------------ADG------TSYSSAYAA----G---------------------------A------------------AALY----LAAKG---TKNI----SPSD----------------------------------------------------------------------------------V---------------------LSAL-------GVT-----------------------------------------------------------------------------------------------------AQQLPVSVSDSSLVSVAVQGAGRLRLSNAI---  59
  60 --------------------------------FSNLPQIQADVVQ-------ASG-NKGK--------------------------G-I--KI--------------G--------------------IID---------------------------G--------------GVDY-T------R-------------E---------P--------------------------------LGG--------------CFGPGC-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------AGGYD---FVGDDYDGTNDPVPDNDPYDNCY--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-I-----------------------SGIIG----AN-EN-------------------------------VY------------GAV----------------------GV--APE-S--SLYVY---RV---FGCN----------G-AA--S------------DDI-------------------------------------V--------LAA--------------M-----------QK---AY--------------------D-----D------D----------M----DV-----------------------------------------INLSLG---------------E--------------------PS--------------------------GWTESTLSVFASR---------LVAR----GT-----I--------------------------------------------------------------------------------------L---------------TISAG-NQ--------GQ---------V-----GGFYSYS---------------------------------------------------------------------------------------------------------------------------------------P-SAGK-G---------------------------V---IN---VG--S------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSSIYPAHLNT----------------------------------------------------SANTTVSFSF----NPIALPNIWTA-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TT-SYF-----S--E--------I-GPT-N----------------------------------------------------------------------D-----LYFAPSVL-----------------A-----P-------------G-----------------TN--------------------------------V------------------------------------------------------------------VG-VTP---------------------------------------------------------------------------------------------------------------------TAFYNW-TI----------------ADG------TSYSSAYAA----G---------------------------A------------------AALY----LAAKG---TNNV----SPSD----------------------------------------------------------------------------------V---------------------LSAF-------EVT-----------------------------------------------------------------------------------------------------AQQLPVSVSDSSLVSVAVQGAGRVQLSDA----  60
  61 --------------------------------------------------------LDGT--------------------------G-V--LV--------------G--------------------IVD---------------------------T--------------GIDYLN--------------------E---------E--------------------------------FMLEDDTTRIISIWDQT--IGRNDVL-GIK---FG-TEYTEEQINQAINLNKQGGDPYSIVPSKDEV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-T-----------------------AGIIG---------------------------------------------------------------------GRGR-NPDLLGA--APN-C--KFAIA---KLAQL--SK------------SVLEYSGVDPNKTEVYGSAE-------------------------------------I--------MLA--------------TRYLANIALRENMP------------------------------------------------------LI-----------------------------------------LYVPVGTNTGGHDG-TNEVEGS-------------LD-TFGRRP--------------------------------------------------------GV-----V--------------------------------------------------------------------------------------P---------------VVGTG-NQGDT--QTHIEGKIEQAGDFK----TIEVKIGKNQKDLNFSIYCSKPDRVSVSITSPSGEMLNRVD-------TKLNFIKD---YKFVYEGTIVDLYYSIPDQLTGDELITLKFRN-----IKDGTWQIRLYGDKIIDGRYWSWLPQRQLLDPDTRFFNPVETTTLVIPATTSG-----------------------------A---VV---SA--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQGFNTTVSGSGRGYTRDG-RIKP--------------------------------------------------------------D-----V------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------IV-----------------------------------------------------------------------------------------------------------------------------------------TKPGGGTTVATG------SSVASSVLA----G---------------------------C------------------CALILQWAIIEK----------NDVEIS----------------------------------------------------------------------------------T------------------KKLISYI-------IAG---------------------------------------------------------------------------------------------------TKM-RKGDVYPNMEWGYG-----------------  61
  62 ---------------------------ELNGIYTLGE-SPVEDSKAPIFHRNPSLNLRGS--------------------------G-V--VV--------------A--------------------IVD---------------------------T--------------GIDYLN--------------------N---------E--------------------------------FMREDETTRILRIWDQT--IDSGKTPDGFI---SG-SEYTEEDINKAIQAQKQGQNPYDIVPSKDDY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TK-M-----------------------AGIVG---------------------------------------------------------------------ARGI-NREIVGV--APD-C--EFIII---KLQEA--SK------------EYVDFYYAKGDKAK-YRNTD-------------------------------------I--------IMA--------------LKYLYELSFTLNKP------------------------------------------------------MI-----------------------------------------IYLPLGSNLGDHAG-ASILERY-------------VDTKISGRN--------------------------------------------------------SL-----F--------------------------------------------------------------------------------------V---------------VTSTG-NQGNT--DTHTSGEIKSNGDSQ----IIELNCGKEQKGLVLQIYAQRPSKIKLGILSPSGERFENTNPRK----TKHILINDAPIWKFIYEGTTVQVTYDSPDEFTGDDKFVIKIEG-----ITEGVWRFILTSNNIVDGKYYAWILQRELLDEDTRFLNPSPYTTLTIPGTAKT-----------------------------I---IN---TS--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNNGAIVSESGRGYTMKD-YIQP--------------------------------------------------------------I-----I------T-----------------A-----G-------------G-----------------IN--------------------------------A------------------------------------------------------------------IT-----------------------------------------------------------------------------------------------------------------------------------------TKPGGGTITMSG------ASVAGAILA----G---------------------------C------------------CALIIQWAVVDG----------NDPQMY----------------------------------------------------------------------------------A------------------TKLQAYI-------IRG---------------------------------------------------------------------------------------------------ARK-REGDTYPNRQWGYGILDMQEIFK--------  62
  63 ------------------------------ETYTLEEISPIEASQVRSLQINLPLQLTGK--------------------------N-V--FV--------------G--------------------IID---------------------------T--------------GIDYLS--------------------D---------E--------------------------------FMTLDGETRIECIWDQT--IITDKED-EIRLVPYG-AFYTKEKINKAIKSYNEGKSPYDIVSSIDEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-M-----------------------AGLIG---------------------------------------------------------------------ATGK-NPELKGV--APD-C--KFAVV---KLIEDYSNK------------ATFDA------KIPVYNITS-------------------------------------I--------FSA--------------LEFLYEYALKKSEP------------------------------------------------------MV-----------------------------------------IYLPLGSNSGNHRG-NGILAEY-------------IE-SISNSR--------------------------------------------------------GI-----V--------------------------------------------------------------------------------------V---------------VTGAG-NERAR--GGHASGSILNAGESR----SIELNVSPDQKYLWAEIWVAPPNIMTVDIVSPSGENTGVIP-------AIINLSED---YNFIFEKTSVKITFYIPEVNTGDELIRIDFFN-----LQPGIWKIKLIANMVLDGAYDIWIPQYGLSIGDTSLSPSDPFGTFTNPGGAIS-----------------------------V---IT---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNNNNIVNYSGMSFLDDY-IDRV--------------------------------------------------------------D-----I------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------LT-----------------------------------------------------------------------------------------------------------------------------------------VAPNNKTKIVNG------TSVAAAVVA----G---------------------------T------------------CAILFEWGIIEG----------NDPYMY----------------------------------------------------------------------------------S------------------QTMKTYL-------TRG---------------------------------------------------------------------------------------------------TRK-RPGDTYPNPQWGFGILDVLGIF---------  63
  64 ------------------------------ETYTLEEISPIEASQVRNVQINLPLQLTGK--------------------------G-V--VV--------------G--------------------IID---------------------------T--------------GIDYLS--------------------D---------E--------------------------------FMTLQGDTRIDCIWDQT--ITSDKDG-EIELIPYG-ALYTKEKINEAIKNYNEGKSPYEIVPSIDEF-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-M-----------------------SGIIG---------------------------------------------------------------------ATGK-NPELKGV--APD-C--KFAIV---KLIEDYSNK------------AAFDA------KIPIYNITS-------------------------------------I--------FSA--------------LEFLYEYALNNSVP------------------------------------------------------MV-----------------------------------------IYLPLGSNSGNHRG-NGILPEY-------------IE-SISNSR--------------------------------------------------------GI-----V--------------------------------------------------------------------------------------V---------------VTGAG-NERDR--GGHASGSILKVGEAR----NIELNVSPEQKYLWAEIWVAPPNVMTVDIVSPSGENTGVIP-------AIINLSED---YNFIFEKTSIKVDFYIPEENTGDELIRIDFFD-----LQPGIWKIKLIANMVLDGAYDIWIPQYGLSIGDTSLSPSDPFGTFTTPGGATS-----------------------------I---IT---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNNNNIVNYSGMSFLNDY-IDRV--------------------------------------------------------------D-----I------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------LA-----------------------------------------------------------------------------------------------------------------------------------------VAPNNETKIVNG------TSVAAAVVA----G---------------------------T------------------CAILFEWGIVEG----------NDPYMY----------------------------------------------------------------------------------S------------------QTIKTYL-------TRG---------------------------------------------------------------------------------------------------TKK-RPGDTYPNPEWGYGILDVLGIF---------  64
  65 ------------------------------ETYTLEEISPIEASQVRNLQINLPLQLTGK--------------------------G-V--VV--------------G--------------------IID---------------------------T--------------GIDYLS--------------------D---------E--------------------------------FMTLQGDTRIDCIWDQT--ITSDKDG-DIELVPYG-ALYVKNKINEAIKAYNEGKSPYDIVPSIDEN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-M-----------------------SGIIG---------------------------------------------------------------------ATGK-NPELKGV--APD-C--KFVVV---KLIEDYSNK------------AQFNA------QVPIFNITA-------------------------------------I--------FSA--------------LEFLYEYALRKSEP------------------------------------------------------MV-----------------------------------------IYLPLGSNSGNHRG-NGILPEY-------------IE-SISNSR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------V---------------VTGAG-NERSR--AGHASGVISKAGETR----NIELNISPNQKYLWVEIWVEAPNIMTVDIVSPSGENTGVIP-------AIINLSED---YNFIFEKTSIKIEFYIPEENTGDELIRIDFFD-----LQPGIWKIKLIANLVLDGAYNMWIPQYGLSIGDTSLSPSDPFGTFTNPGDSTS-----------------------------I---IT---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNNNNIVNYSGMSFLDDY-IDRV--------------------------------------------------------------D-----I------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------IT-----------------------------------------------------------------------------------------------------------------------------------------VAPNNSIATVNG------TSVSAAVVA----G---------------------------T------------------CAILFQWGIIEG----------NDPYMY----------------------------------------------------------------------------------S------------------QTMKTYL-------TRG---------------------------------------------------------------------------------------------------TKQ-RPGDSYPNPQWGYGILDVLGIF---------  65
  66 ------------------------------ETYTLEEISPIDAAQVRSLQINLPLQLTGE--------------------------G-V--VV--------------G--------------------IID---------------------------T--------------GIDYLS--------------------D---------E--------------------------------FMTLNGESRIECIWDQT--IVSEKDD-EIELVPYG-ALYLKDKINEAINAYRQGKSPYDIVPSIDEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-M-----------------------SGIIG---------------------------------------------------------------------ATGK-NPELKGV--APD-C--KFVVV---KLIEDYSNK------------AQFNA------QIPIFNITA-------------------------------------I--------FSA--------------LEFLYEHALRKSEP------------------------------------------------------MV-----------------------------------------IYLPLGSNSGNHRG-NGILAEY-------------IE-SISNSR--------------------------------------------------------GI-----V--------------------------------------------------------------------------------------V---------------VTGAG-NERSR--AGHASGVISKAGETR----SIELNVSPNQKYLWVEIWVDPPNIMTVDIVSPSGENTGVVP-------AIINLSED---YNFIFEKTSIKIEFYIPEENTGDELIRIQFYD-----LQPGIWKIKLIANLVLDGTYNIWIPQYGLSVGDTSLSPSDPFGTFTNPGGSTS-----------------------------I---IT---VA--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNNNNIVNYSGMSFLNDY-IDRV--------------------------------------------------------------D-----I------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------VT-----------------------------------------------------------------------------------------------------------------------------------------VAPNNSTTTVNG------TSVSAAVVA----G---------------------------T------------------CAMLFQWGIVDG----------NDPYMY----------------------------------------------------------------------------------S------------------QTIKTYL-------TRG---------------------------------------------------------------------------------------------------TKQ-RPGDSYPNPEWGYGALDVNGIF---------  66
  67 ------------------------------ELYTLEDISPIEEAQISSIQQSNPLNLLGD--------------------------N-V--VV--------------G--------------------IID---------------------------T--------------GIDYLN--------------------E---------E--------------------------------FITDDNKTRINFIWDQSLDIFEDING-ELK---YG-EIYKKDDINKAIELYKQGGNPYDIVKTKDEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-M-----------------------AGIIA---------------------------------------------------------------------ASGK-NPELRGG--APK-C--ELCII---KLAEAVSYK------------EDFEI------EVPVYNVTS-------------------------------------I--------VIA--------------IETLYKYAIEYKKP------------------------------------------------------LV-----------------------------------------IYLPLGTNSGNHQG-TGLLNEY-------------IE-NVTNNR--------------------------------------------------------GI-----I--------------------------------------------------------------------------------------V---------------VTGAG-NEGDV--GHHASGIIEKKDMID----DIELYVAERQKVLISDIWIDMPNIMSVNVISPSGEETGVLV-------PLLKKENK---YKFIFENTVVDIRYYIPEETTGDEYIQIYLYD-----IQPGLWTFRIIGNIISSGIFNIWIPQKGITKPGTGFRAPDPYGTLTIPGDSAS-----------------------------V---VT---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQNTNNALIYSSMTFKNSE-VSII--------------------------------------------------------------D-----L------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------IT-----------------------------------------------------------------------------------------------------------------------------------------TASNNSTTTVSG------TSVSAAVVA----G---------------------------V------------------CALLLEWGIVDG----------NYPYMY----------------------------------------------------------------------------------C------------------QSLISYL-------VKG---------------------------------------------------------------------------------------------------TDR-RKGDIYPNAQWGYGTLNVLKMF---------  67
  68 ----------------------------LGGIYTLSSTSPIEASKVENFHNSPYLKLTGK--------------------------D-V--IV--------------G--------------------IID---------------------------T--------------GIDYLN--------------------P---------E--------------------------------FTDSNGKTRILKIWDQS--LKTDKYPKDMF---YG-TEYSEEEINQAIELNNSGGDPYTIVQSKDDV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-M-----------------------ACIIA---------------------------------------------------------------------GSGK-DENLTGV--VPE-C--DLAIV---KLDRA--FK------------KYTDYFFAKGDAVK-YRNVD-------------------------------------I--------LLA--------------MKYLYNLSFQYNKP------------------------------------------------------MV-----------------------------------------IYIPMGTNFGAHDG-SSILERY-------------IN-DISNKR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------V---------------IASSG-NQGNT--NTHADGIITEMGDNK----TIELDVGEDQDGIMMIILGYKPDKFKLSIISPSGELIENANPLTNYGGNKNLAVENGYKINFIYEGTTMDVFYDSPDELTGGERIVIRAQN-----LKPGIWRFRLTGQHITFGNFDAYILQKELLAEGTKFLISSPYTTLTIPGAAEK-----------------------------M---IT---VA--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NQENNTILSSSGRGYARND-IIQP--------------------------------------------------------------I-----I------A-----------------A-----G-------------G-----------------VN--------------------------------A------------------------------------------------------------------LT-----------------------------------------------------------------------------------------------------------------------------------------INNKGEKVSVSG------GSVAAAIVA----G---------------------------C------------------CAMLFQWGIVYN----------NDPTLY----------------------------------------------------------------------------------V------------------AKLQTYL-------IRG---------------------------------------------------------------------------------------------------VNT-REGDMYPNREWGYGTIDMINVFN--------  68
  69 -----------------------------RSMSVLQDISPNSIDQILAIKKNPYLNLTGK--------------------------G-V--LV--------------G--------------------IVD---------------------------T--------------GIDYLN--------------------N---------E--------------------------------FIREDGTSRIAAIWDQT--IQDVKAE-SVY---LG-NIYSNEEINKAINAYKNNQDPYSIVPSKDDI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TE-M-----------------------AGIIG---------------------------------------------------------------------ARGY-NGEFQGV--AND-C--EFVIV---KLLESLNFQ------------KILQSNNVK--YTPIYNSAE-------------------------------------I--------VAG--------------IEYLKNYSISMNKP------------------------------------------------------IV-----------------------------------------IYLGIGATEGSHDG-NNLISKY-------------LT-SIASIR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------L---------------VAGVG-NEGAA--EGHASGTIENVGETD----SIELNIPREMKNFSFNIWVKRPNKMSLNVISPTGEESSFIQ-------AKRNKKEE---INFVFSNAKLKINYYMLEDFSGHEVIQVIFED-----INPGIWKFALRGDYISGGEYNAWLQPKVTLPENTKFLEPDPFSTLTIPSTARK-----------------------------I---IT---VS--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H--GLVNESLIATSGKGFNTNG-LINP--------------------------------------------------------------D-----I------A-----------------T-----V-------------G-----------------IN--------------------------------I------------------------------------------------------------------LT-----------------------------------------------------------------------------------------------------------------------------------------TKALGETTVVSG------SSAATAVVA----G---------------------------V------------------CALLLQWGIVDG----------NDTTMY----------------------------------------------------------------------------------S------------------TKIRSYL-------VYG---------------------------------------------------------------------------------------------------AYR-KPELVYPNRETGYGSFDILGTF---------  69
  70 -----------------------------RSMSVLQDISPSSIDQILTIKKNPYLNLTGK--------------------------G-V--LV--------------G--------------------IVD---------------------------T--------------GIDYLN--------------------N---------E--------------------------------FIREDGTSRIAAIWDQT--IENIKAE-SVY---LG-NIYSNEEINKAINAYKNKEDPYAIVPSKDDI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-M-----------------------AGIIG---------------------------------------------------------------------ARGY-NGEFQGV--AND-C--EFVIV---KLLESLNFQ------------KILQSNNVK--YTPVYNSSE-------------------------------------I--------VAG--------------IEYLKNFSVRMNKP------------------------------------------------------MV-----------------------------------------IYLGIGTTEGSHDG-NNLISKY-------------LT-SIASIR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------L---------------VAGVG-NEGAA--EGHASGIIKNVGETD----SVELNIPREMKNFSLHIWVKRPNKMSLNVISHTGEESSFIQ-------AKRNKREE---INFVFSKTNLKLNYYMPEHFSGHEVIEVIFKD-----INPGIWKFVLRGDYISDGAYNTWLQPKVTLPENTKFLEPDPFSTLTIPATARK-----------------------------V---VT---VA--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H--GLLNESVIATSGKGFNTNN-LINP--------------------------------------------------------------D-----I------A-----------------T-----I-------------G-----------------VN--------------------------------I------------------------------------------------------------------LT-----------------------------------------------------------------------------------------------------------------------------------------TKALGEATVVSG------SSAAAAVVA----G---------------------------G------------------CALLLQWGIVDG----------NDTTMY----------------------------------------------------------------------------------S------------------TKIRSYL-------VYG---------------------------------------------------------------------------------------------------AYR-KPEYTYPNRETGYGSFDILGTF---------  70
  71 -----------------------------RSMFVLQDVSPNSIDQILAIKKNPYLNLTGK--------------------------G-V--LV--------------G--------------------IVD---------------------------T--------------GIDYLN--------------------K---------E--------------------------------FIREDGTSRVAAIWDQT--IQDIKAE-SVY---LG-NIYSNEEINKAINAYKGNEDPYAIVPSKDEI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-M-----------------------AGIIG---------------------------------------------------------------------ARGY-NGDFQGV--AND-C--EFVIV---KLLESLNFQ------------KILQSNNVK--YTPIYNSSE-------------------------------------I--------VAG--------------IEYLKNFSVKMNKP------------------------------------------------------MV-----------------------------------------IYLGVGTTEGSHDV-NNLISRY-------------LT-SIASVR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------L---------------VAGVG-NEGAA--EGHASGVIKNIGEID----TMELNIPREIKNFSFLIWVKRPNKMSLNVISPTGEESSFIQ-------AKRNKREE---INFIFSNAKLKINYYMPEDFSGHEVIQVIFKD-----INPGIWKFVLRGDYISDGEYNVWLQPVITLPENIKFLESNPFSTLTIPSTARK-----------------------------V---VT---VA--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H--GLVNESLIATSGKGFNTNG-LINP--------------------------------------------------------------D-----I------S-----------------T-----V-------------G-----------------IN--------------------------------I------------------------------------------------------------------LT-----------------------------------------------------------------------------------------------------------------------------------------TKALGETTLVSG------SSAATAVIA----G---------------------------G------------------CALLLQWGIIDG----------NDTTMY----------------------------------------------------------------------------------S------------------TKIRSYL-------IYG---------------------------------------------------------------------------------------------------AYR-KPELTYPNRESGYGSFNLLGTF---------  71
  72 ---------------------------------VLQDVEVNNSHDIGVIKSNPYLNLSGQ--------------------------G-V--LV--------------G--------------------IID---------------------------S--------------GIDYLN--------------------N---------E--------------------------------FINEDETSRIVNIWDQT--AKYNNKE-EVY---IG-DIFTRDDINKAIEAKKQNKNPYDIVPTKDEY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TK-V-----------------------AGIIG---------------------------------------------------------------------AKGY-NKEVGGA--APN-C--EFVIV---KLQEALFLK------------RYILTNGIK--DVPVYNNVE-------------------------------------L--------LSG--------------IEYLRKYSLKENKP------------------------------------------------------MV-----------------------------------------IYIGIGTTNGSHDG-KNITSKY-------------LK-KVGGTR--------------------------------------------------------GI-----A--------------------------------------------------------------------------------------L---------------VAGVG-NEGDS--EGHVSNYIKDVEDVK----SNELNISKEFKDLTFYIWIRRPNQMSINIISPSGEQSSFIS-------SKIDRSEE---VKFVLVDTKAIVKYYIPENFTGHQVISLNFKD-----MKAGIWRIQLRGEYIIDGRYDIWLPSKKLLHEGTKFLDPDPYATLTVPSTAEK-----------------------------V---VT---VS--Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--NSQNGALVASSGNGFNTNG-LINP--------------------------------------------------------------D-----I------T-----------------A-----G-------------G-----------------VN--------------------------------I------------------------------------------------------------------VT-----------------------------------------------------------------------------------------------------------------------------------------TSNNNEVSTMSG------SSAATAIVA----G---------------------------C------------------CALLLQWGIING----------NDKTMY----------------------------------------------------------------------------------S------------------IKIRSYL-------AYG---------------------------------------------------------------------------------------------------ARR-YGIKEYPSRELGFGELDLSETF---------  72
  73 PLFPRQWGLTLAGF----PEAWARGR--------------------------------GE--------------------------G-V--VV--------------A--------------------VPD---------------------------T--------------GVLK-D------H-------------P---------D--------------------------------L---------------------Q----------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALLPGLDLVD---------------G------------DA-----------------------------------------------------------------------------------------D---P---------------------EEPVVGGFQ----------------------------------------------------------------------TF-------------------------------------------------------------------HG-------SH-V-----------------------ASIAA------------------------------------------------------------APWNG-V------------GMAGASQ-A--RVLPI----------------------R------------------LLDPGGSGREGDLILALRWAVGLAEGLPPNPHPAR----------------------------------------------------------------------------------------------------V-----------------------------------------VNLS---LAG--AG-PCS-------------------------A--------------------------PLQE-----AIDE-A--------RAR----GV-----L--------------------------------------------------------------------------------------V---------------VAAAG-NQ--------GE---------D------------------------------------------------------------------------------------------------------------------------------------------------------YRG-Y----FPANCRG----------------V---LA---VG--A------------------------------V-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------DG-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-APY-----A--N--------R-G-------------------------A------------------------------------------------P-----L------L-----------------A-----P-------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNTGLGPEA--------GI-LG-AGFLPGQGMGW--RYLQG------TSQAAPHVA----G---------------------------A------------------AA-I----LL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GM-GADPDAA-------QGALLAGA--------  73
  74 ---------------------------------WGAEAIGAFQAH-------RRG-LSGQ--------------------------G-V--AV--------------A--------------------VLD---------------------------T--------------GVD-----------------------P-----------------------------------------------VV----------PQLPGYDFVEEDATPQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DAFPG------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TG-A-----------------------AGLVK-------------------------------------------------------------------------------EV--APD-A--DILPV---RV---CDQS----------G-VC--R------------ASR-------------------------------------V--------VRG--------------V-----------CW--VVA--------------------------------------------NRQGPTV-----------------------------------------LNLSLGG------D-TPVEALK-------------LALEAALSQ--------------------------------------------------------GI-----P--------------------------------------------------------------------------------------V---------------AAAAG-NQ--------GNQGSPAHY------------------------------------------------------------------------------------------------------------------------------------------------------PAAFDLPG---------------------------L---VA---VAALD------------------------------K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PAPY-----N--T--------R-GTY-V----------------------------------------------------------------------D-----L------A-----------------A-----P-------------G-----------------TD--------------------------------L------------------------------------------------------------------ECMTPGG---GQRL--------------------------------------------------------------------------------------------------------------------------------------CTG------TSFATPLVA----G----------------------------------------------AMAL----WLS----AQPD-------LT-----------------------------------------------------------------PAQ--------------L---------------------QQRL-------EEN-------------------------------------------------------------------------------------ARPLPFP------------------PQEVGKGMLDL-------------  74
  75 --------------------------------------------------------------------------------------------V--------------A--------------------VFD---------------------------T--------------GVSP-I------A-------------A---------T--------------------------------ITPWVV-S---------------------------------RETYVIPPDT--SY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TM-V-----------------------SSLI------------------------------------------------------------------------------------------------SGAHF-------------------LN---------------DNHPW------------IPDTKSKIHDVCALDENGSYISDL--------ILRLADAVNKR-PD---I-------------------------------------------------------------------KV-----------------------------------------WNLSLG--GGPCNEQTFSDFAM-------------ELDRLSDKF--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------F---------------VVAAG-NYVDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIRTWPNPDP---LGGADLISSPGESVRA---LT---VGSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HME---------------------------------------------------------------------------------ANDALSEIGTPTPY-----T-----------RRGPG-------------------------------------------------------------------------------------------------------------PVFT-PKPDIIHAGG--GV-----------HRPW--------------------------------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGASSLKVVGP-DNRLCSNFG------TSFAAPIVA----S---------------------------L------------------AAHT----WQ-----------------------------------------------------------------------------------RIATNTDF--NVSP----------------------SLIKALL-------IHSAQLSSPDYSPSERRYLGAGIPN----------------------------------------------------------------------------------------------------------------  75
  76 --------------------------------------------------------------------------------------------V--------------A--------------------VFD---------------------------T--------------GVSP-I------A-------------A---------T--------------------------------ITPWVV-S---------------------------------RETYVIPPDT--SY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TM-V-----------------------SSLI------------------------------------------------------------------------------------------------SGAHF-------------------LN---------------DNHPW------------IPDTKSKIHDVCALDENGSYISDL--------ILRLADAVNKR-PD---I-------------------------------------------------------------------KV-----------------------------------------WNLSLG--GGPCNEQMFSDFAM-------------ELDRLSDKF--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------F---------------VVAAG-NYVDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIRTWPNPDP---LGGADLISSPGESVRA---LT---VGSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HME---------------------------------------------------------------------------------ANDALSEIGTPTPY-----T-----------RRGPG-------------------------------------------------------------------------------------------------------------PVFT-PKPDIIHAGG--GV-----------HRPW--------------------------------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGASSLKVVGP-DNRLCSNFG------TSFAAPIVA----S---------------------------L------------------AAHT----WQ-----------------------------------------------------------------------------------RIATNSDF--NVSP----------------------SLIKALL-------IHSAQLSSPDYSPSERRYLGAGIPN----------------------------------------------------------------------------------------------------------------  76
  77 --------------------------------------------------------------------------------------------V--------------A--------------------VFD---------------------------T--------------GVSP-I------A-------------A---------T--------------------------------ITPWVV-S---------------------------------RETYVIPPDT--SY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TM-V-----------------------SSLI------------------------------------------------------------------------------------------------SGAHF-------------------LN---------------DNHPW------------IPDTKSKIHDVCALDENGSYISDL--------ILRLADAVNKR-PD---I-------------------------------------------------------------------KV-----------------------------------------WNLSLG--GGPCNEQMFSDFAM-------------ELDRLSDKF--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------F---------------VVAAG-NYVDE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------PIRTWPNPDP---LGGADLISSPGESVRA---LT---VGSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HME---------------------------------------------------------------------------------ANDALSEIGTPTPY-----T-----------RRGPG-------------------------------------------------------------------------------------------------------------PVFT-PKPDIIHAGG--GV-----------HRPW--------------------------------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGASSLKVVGP-DNRLCSNFG------TSFAAPIVA----S---------------------------L------------------AAHT----WQ-----------------------------------------------------------------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------  77
  78 --------ATFLPRDPLYPRQWNLAAIRMPQ---------AWALW-------QAQ-KTIA--------------------------P-V--TV--------------A--------------------VLD---------------------------T--------------GY-V-A------S-------------P---------E--------------------------------L------------------AGRVVNGYDFVSD-----------AARSGDGGRRDRDAGAVGQFA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------EI-V-----------------------ANLIA----AAHDG-------------------------------RG------------MA-----------------------GI--NPR-A--RIVHVRVADV-------------------NGQIA------------PQD-------------------------------------L--------VDG--------------L-----------RW---AA---------------------------------GLSVPGVPNNPNPA--RV-----------------------------------------LNLSLFADFIPLTG-CDARIQK---------------------------------------------------------AVDD---------VTAK----GA-----L--------------------------------------------------------------------------------------V---------------VVGAG-NDGRD--ASGYS-------------------------------------------------------------------------------------------------------------------------------------------------------------P-AGCRNV-------------------------------LT---VT--S------------------------------VDERGLR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PGY-----A--N--------W-GRA-V----------------------------------------------------------------------S-----L------G-----------------A-----P-------------G-----------------GD--------------------------------P------------------------------------------------------------------AH---------------------------------------------------------------------------------------------------GVVASSV---------------SGSGGE-RD----------------PNG------TSFAAPHAA----G---------------------------V------------------ASLL----LS------------VRPELS-----------------------------------------------------------------RAT--------------L---------------------TTLL-------TRQVTPFASGRCDTDPRHTCGAGLLNAEAALQ---------------------------------------------------------------------------------------------------------  78
  79 P----PWSNTYLGV----ADAHKFAT--------------------------------GA--------------------------G-V--TV--------------A--------------------VID---------------------------T--------------GV-D-A------S-------------P---------R--------------------------------V---------------------P----------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E--PGGDFVDQAGNG---------LS------------DC-----------------------------------------------------------------------------------------D---A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TL-T-----------------------ASIIA----GR-----------------------------------------------------PAPTDGFV------------GV--APD-A--RLLSL----------------------RQTS--E------------AFEPVGS---------------QANPNDPNATPAAGSIRSL--------ARA--------------V-----------VH---AA-----NLG------------------------------------V----GV-----------------------------------------INIS---EAA--CY-KVS-------------------------R--------------------------PIDETSLGASIDY-A-------VNVK----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NT--------GG---------D--------CVQN---------------------------------------------------------------------------------------------------------------------------------------P-APDP-S----TPGDPRGWNNVQTVVTPAWYAPLV---LS---VG--G------------------------------I-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------TG-------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-SSF-----S--M--------H-G---P--------------------WV------------------------------------------------D-----V------A-----------------A-----P-------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENIVALGDTG-EPVN--------AL-QGREGPVP----------IAG------TSFAAAYVS----G---------------------------L------------------AA-L----LR----Q-------RFPDLT-----------------------------------------------------------------PAQ--------------I---------------------IHRI-------TAT-------------------------AR------------------------------------------------------------------------HPGG-GVDDLVG-------AGVIDAVAALT-----  79
  80 --PNYLYFPLYVPNDPLYPASPLDASRLQPYYQAIRLEA-------------AWD-LLGS--------------------------LPFTPVV--------------A--------------------VLD---------------------------T--------------AFNP-T------H-------------P---------D--------------------------------LQA--------------SLLPG-RNLTPDGLPPEN-LSPSPPPQGFAYGSGDA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------QG-V-----------------------AGLVA----AVADN-------------------------------NE------------GIP----------------------GV--GLNRV--KVLPL---KVF---YWV----------SGSY--S------------STS-----------------------------------AVL--------ASA--------------I-----------RY---AA--------------------D-----Q------G----------A----AV-----------------------------------------VNLSLG----SPTP-LDRVVQG---------------------------------------------------------ALGY---------ALSK----GT-----L--------------------------------------------------------------------------------------P---------------VAASG-NA--------GA---------DGLY-Y----------------------------------------------------------------------------------------------------------------------------------------------PAAYPG-----------------------------V---LA---VG--S------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------LD-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--T--------R-S--------------------------------------------------------------------------D--------------------------------------------------------------------FS--------------------------------N------------------------------------------------------------------CS-TAP-----------------------------------------------------------------------------------------------TDLVLAAAG-NRN-PSQTLWSLALGQNY------PYYRTLGAY--ARWAG------TSFAAPQAS----A---------------------------L------------------AALY----VAKYYAR-------YGQGPG-----------------------------------------------------------------PDQ--------------I---------------------RLCL-------TRT-----------------------------------------------------------------------------------------------------A--SNGGRYDPQTGYG-----------------  80
  81 PL---QWAFPLMGYGAVWRDMDAGGY--------------------------------TR--------------------------P-V--TV--------------A--------------------VAD---------------------------S--------------GVRY-D------H-------------P---------D--------------------------------L-A--------------GQLWTP----------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E--GALDVLSGTDNG------DGDGP------------DR-----------------------------------------------------------------------------------------D---P---------------------TDPSFAGRK----------------------------------------------------------------------TE------------------------------------------------------------------SHG-------TH-V-----------------------TGIIV----ARWGQ-------------------------------NA------------PSCAGCSP-TGVV------------GASYKAP-I--KVLPI---RV---LDTQ----------GN-T--D------------LAD-------------------------------------V--------INA--------------V-----------R-----Y-----AAGLPVKLGEQVYTNP-----H------P----------A----QV-----------------------------------------LNLSLGGEGI--ST-AEA-------------------------Q--------------------------PMCD-----AVAQ-A--------RER----GT-----L--------------------------------------------------------------------------------------T---------------FAAAG-NS--------GT---------G--------QPYY---------------------------------------------------------------------------------------------------------------------------------------P-A----A----CPA--------------------A---VA---VG--S------------------------------V-----------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LTAAG-------------------------------------------------------------------------------------TP-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-ATY-----S--N--------H-Y---A--------------------QV------------------------------------------------Q-----L------S-----------------A-----P-------------G-----------------GS----------------------SVLAPTYYAGG------------------------------------------------------------------TF-GGE-----------------------------------------------------------------------------------------------PFPDDIVSTGWDYQKDEP--------NY-VA----------------MAG------TSQATPQVA----A---------------------------V------------------AA-L----LL----S-------KGVTQG-----------------------------------------------------------------PDD--------------T---------------------LARL-------TAT-------------------------ST------------------------------------------------------------------------DLGAPGRDDFYG-------FGMVNAAAALG-----  81
  82 -TGAPQVLGGEDLAAAKAASAKAEGQDPLESLQWDLPAIKADKAH-------EKS-LGSR--------------------------K-V--TV--------------A--------------------VID---------------------------T--------------GVDD-T------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNF-------------------------------------DR---QAS-------------------------VNCVAGKPDTADGAWRPSAAES------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHG-------TH-V-----------------------AGEIA----AAKNG-------------------------------VG------------MT-----------------------GV--APG-V--KVAGI---KVSNPDGFF----------------Y------------TEA-------------------------------------V--------VCG--------------F-----------MW--AAE--------------------------------------------HGV--DV-----------------------------------------TNNSYYTDP------------W-------------YFNCKDDPDQKALVEA-------------------------------------VSR-ASRYAEKKGA-----V--------------------------------------------------------------------------------------N---------------VAAAG-NE-NY--DLTSDEITDPSSPNDTTPGDRTVDPSKCLDIPTQL-------------------------------------------------------------------------------------------------------------------------------PGV------------------------------------VT---VA--A------------------------------TGAKGLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSF-----S--N--------H----------------------------------------------------------------------------GLGVIDI------A-----------------A-----P-------------G-----------------GD--------------------------------S------------------------------------------------------------------TA-YQT-----------------------------------------------------------------------------------------------PEPPATSGLI---------LGTLPGGKW-GY----------------MAG------TSMASPHVA----G---------------------------V------------------AALI----KS------------THPHAS-----------------------------------------------------------------PAM--------------V---------------------KALL-------YAE----------------------------------------------------------------------------------ADATACTKPYDIDGDGKVDAVCEGPKNRNGFYGWGMADALDAVTW-------  82
  83 PLRERQW-------ALGTIAAYDA--------------------W-------DIT-TGGP----------------------------I--VV--------------A--------------------VID---------------------------T--------------GIDA-S------H-------------P---------E--------------------------------L---------------------E----------------G-----------------------------------------------------RVL----------------------------------------------------------------------------------------------------------------------------------GG---------------FNAITGSTD------------VS-----------------------------------------------------------------------------------------D---D---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------AGLIA----ASG-D-------------------------------NG------------VGIA---------------------GM--CWG-C--VILPI---KA---CLSS----------G-RC--R------------DSS-------------------------------------V--------ISA--------------I-----------RW---AT--------------------D-----N------G----------A----RI-----------------------------------------INLSLG---------GTL---A--------------------SP--------------------------ALHE-----AVRY-A--------TER----GV-----L--------------------------------------------------------------------------------------V---------------VAASG-NE--------RA---------E--GNA---PNY----------------------------------------------------------------------------------------------------------------------------------------P-A--A-Y----PE---------------------T---VA---IG--A------------------------------S-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-------------------------------------------------------------------------------------SD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-TGF-----S--N--------T-G---E--------------------FI------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VT-TTP--------------------------------------------------------------------------------------------------------G-------N--------SY-AL----------------ATG------TSFASPFAS----G---------------------------A------------------AA------------------------------------------------------------------------------------------------------------L---------------------VMTI-------RPD------------------------LSS------------------------------------------------------------------------ADVRCILSVAADDRGAPGRDGEYGYGRLNVLAAIQ  83
  84 T---AAW-----------------------------QQIGLPAAQ-------ASA-PNAG--------------------------KSQ--VI--------------A--------------------VID---------------------------T--------------GVDL-E------H-------------P---------A--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGALTPASTWLDLVDGDTLPQDDGEL------------GT-----------------------------------------------------------------------------------------G---G---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------AGIAT----Q---------------------------------------------------------------------------V--APM-V--QIMPV---RA---LGTD----------G-SG--D------------ISA-------------------------------------V--------VQA--------------I-----------VW---AV--------------------D-----H------G----------A----NI-----------------------------------------INLSLG---------SNE---A--------------------SE--------------------------ALQS-----AVRY-A--------DEK----GV-----A--------------------------------------------------------------------------------------V---------------VAAAG-NA--------GN---------N--------ELTY---------------------------------------------------------------------------------------------------------------------------------------P-A--A-YARTSAG---------------------L---LS---VG--S------------------------------V-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------SD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SGF-----S--N--------Y-A---A--------------------SL------------------------------------------------E-----V------L-----------------A-----P-------------G-----------------ER--------------------------------I------------------------------------------------------------------AT-Y----------------------------------------------------------------------------------------------------------APNN-------------KL-AL----------------WTG------TSMSAPVVA----G---------------------------L------------------LALM----QGERQAA-------GGEN----------------------------------------------------------------------A--------------------------------------V-------TAH------------------------AHD------------------------------------------------------------------------ISGIALNQPFTGG-LGYGRIDAAATVL--------  84
  85 -----QAIPGGNLTRARVQAFMPT-------NAM--------------------Q-DQAR--------------------------G-I--WL--------------Q--------------------LAD---------------------------N--------------GL----------------------------------D--------------------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAIAEAKEAYESQARYGLD-TLFAPHAT-----APTAG--------------------------------------------------------------------------ARDIMGP---------D-A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TH-V-----------------------AGIIG----AVRDA-------------------------------AN------------PVQ----------------------GI--APN-V--RLMGV---RA---VPDG------------DERDP--------------D-------------------------------------I--------ARA--------------V-----------RY--------------------------------AVDNG-A---------------QI-----------------------------------------INMSFGKAWSPQ-------KP----------------------------------------------------------VVDSAM-R------YAA--SKGV-----L--------------------------------------------------------------------------------------L---------------VHAAG-ND-------------------------SENNDVS---------------------------------------------------------------------------------------------------------------------------------------P-SFPSSVTVEGAR---------------------VETWIE---VG--A------------------------------SSWKGK----DKLA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATF-----S--N--------Y-G------KSRV----------------------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------LSTVPG-----------------------------------------------------------------------------------------------------------------------------GGVKRES------------G------TSMAAPVVS----G---------------------------V------------------AALL----------MA------YFPNLT-----------------------------------------------------------------AAQ--------------V---------------------KEIL------------------------------------------------------------------------------------------------------------------------------------------------  85
  86 ------------------------------------------------------------------AW-----NITQGVD-------SV--LL--------------A--------------------IID---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MNKI-------------------------------------YLNAGETG-------------------------F-D-------SFGNDGGDYLN--------------------WDNDPFDDQG--------------------------------------------------------------------------------------------------------------------------------------------HG-------TF-I-----------------------AGIAA----AETNN-------------------------------FI------------GIA----------------------GT--APN-I--KLLNL---RA---FDPG----------G-YG--E------------EDD-------------------------------------V--------AAA--------------I-----------LY---AI---------------------------------K----------MNA--KV-----------------------------------------INMSFG-DNSFSLV---------------------------LRD-----------------------------------VIQY---------AYSQ----NL-----V--------------------------------------------------------------------------------------L---------------IASAG-NS--------GSNLPHY--------------------------------------------------------------------------------------------------------------------------------------------------------PSGYSE-----------------------------V---IS---VG--N------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TPDDFV-AGS-----S--N--------W-GST-I----------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------TG--------------------------------I------------------------------------------------------------------L--TTS-----------------------------------------------------------------------------------------KN--S-G--------------------------Y-AS----------------ING------TSASAPFVS----A---------------------------T------------------AALILSLQ-NFSNEE-----------------------------------------------------------------------------------------------I---------------------KQIL-------KST------------------------------------------------------------------------------TDDIGES-----------------------GWDLRSGAGRLNTEKAL---------  86
  87 --------------------------KLRALKLPNDTCFSYRWDLEAIDAPEAWDRSVGS--------------------------QEV--YV--------------A--------------------VFD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------LKDNLWKNPDEVCDNGVDDDGNG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YVDDCYGVNVLCYPRGYYDTNAPGCNAPDAYDDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TL-I-----------------------AGIIG----AVGNN-----------------------------------------------------------------GFLIPGV--AWR-V--KIIPC---KF-------------------------------------------------------------------------------------LDA-----------------------------------------------------------SGFGELEGELACFEYIKKLERDKGIKVIA-------------------------------------INASYGGEYLFSRVQYE--------------------------------------------------------------EISNFN---------------GV-----Y--------------------------------------------------------------------------------------I----------------TASG-NYGDNNDEIDFY-------------------------------------------------------------------------------------------------------------------------------------------------------------PCNYN------------------------------LDNEIC---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDVYKKPAYF-----S--N--------Y-GYYTV----------------------------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------EE--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LGLYTGKHSNSCEKSLVLGAG------TSLSAPFVT----G---------------------------A------------------VALL----YS------------LNRNLS-----------------------------------------------------------------PREIKREILLTGENSKDYDGKSYTCNLLNLNNLLSGESSQKMC-------LSTGELNFGTLNSGESKTLSLTVRSTGK-------------------------------------------------------------------------------------------------------------  87
  88 SMSETTSKKTPFEASMPTDSALESKLYGMHMITA-------THAW-------IHG-EAGD--------------------------G-T--VV--------------A--------------------VVD---------------------------S--------------GISR-H------H-----------------------D--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DCN-------------------------LWQNPHEQQDGR-----DDDGNGLIDDNHGYDFQENKSEPEDEN--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----ACVNG---------------------------------------------------------------GGV---VGG--APK-T--QLMAL---RF---IGKG----------G-QG--S------------MAN-------------------------------------S--------IRA--------------L-----------NY--------------------------------------A----------IDHEVQV-----------------------------------------INNSWGGPQSTTVL-RRLVHMS---------------------------------------------------------AVAR----------NGK----GI-----L--------------------------------------------------------------------------------------L---------------INAAG-NE--------SSNNDV--NPSY---------------------------------------------------------------------------------------------------------------------------------------------------PANWDQDN---------------------------T---IS---VA--A------------------------------IDINGDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADF-----S--N--------Y-GKS-SV---------------------------------------------------------------------D-----M------A-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------YS-TKP-----------------------------------------------------------------------------------------------------------------------GGDY-QH----------------MSG------TSMATPHVS----A---------------------------V------------------AALVFGAFLRNGYDAPA----------------------------------------------------------------------------A-E--------------V---------------------KDII-------RIT-----------------------------------------------------------------------ASPVEQLQGVTRWGSIPHARDAVLMARMGGMFLQAKCEDMVFE----LDAGSAHVVDLHLMPY  88
  89 -------------------LPWGIERIKAHKAWK--------------------W-SKGR--------------------------G-I--RV--------------A--------------------VID---------------------------T--------------GIAD-D------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAIR-------------------------DNYRGGINILSPYHTPRDYN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----GRTAE---------------------------------------------------------------AGI---VGV--APE-T--HIYGV---KA---FNRK------------GSANL------------SDL----------------------------------------------LSA--------------I-----------NW--------------------------------------C----------IENKMHV-----------------------------------------INMSFGM---------DKVSES-------------LRH-----------------------------------------AIQI---------AHRK----GI-----L--------------------------------------------------------------------------------------M---------------VAAAG-NQ--------GMSSR-IDF------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARYPE------------------------------TIA-----------------------------------VTSISKN-------------------------------------GEL-------------------------------------------------------------------------------------------------------------SVF-----SNIS--------K-G---------V----------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------DR--------------------------------I------------------------------------------------------------------LS-AWLNHSKRE----------------------------------------------------------------------------------------------------------------------------------------MSG------TSMAVPHVT----G---------------------------T------------------ISLL----LH------------LNPYLN-----------------------------------------------------------------PEQ--------------V---------------------RYIL-------TQSAEK-----------------------------------------------------------------------------------------------------------------------------------  89
  90 ----------------------------EYAAAWGAQHIGADQVA-------AAG-ITGA--------------------------G-V--RV--------------A--------------------VLD---------------------------T--------------GIDY-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY-----------------------------------------------------------------------------------KGGYN---FV------ADNNDPMDDAYSL----------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGIIA----AR-NN-------------------------------GT------------GVV----------------------GV--APA-A--ELYAV---KV---LNGG----------L-GG--E------------LSD-------------------------------------I--------IAG--------------I-----------EW---AI--------------------E-----N------R----------M----QV-----------------------------------------VNMSFG---------------S--------------------ME----------------------------FSQALKDVCDL---------AYRS----GI-----V--------------------------------------------------------------------------------------L---------------VASAG-NF--------SP---------G--------AVLY---------------------------------------------------------------------------------------------------------------------------------------P-AAFD-S---------------------------V---VA---VS--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-------------------------------------------------------------------------------------QD-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TL-GTF-----S--S--------Y-GPQ-V----------------------------------------------------------------------E-----L------A-----------------A-----P-------------G-----------------HN--------------------------------I------------------------------------------------------------------YS-TAI---------------------------------------------------------------------------------------------------------------------G--GGY-RI----------------NFG------TSQAAPHVT----G---------------------------A------------------AALL----ISAGT---TDTNGNRSVADE----------------------------------------------------------------------------------V---------------------RQRL-------AAA-----------------------------------------------------------------------------------------------------ARDLGEMGRDIYYGYGLVDVAKAVL--------  90
  91 --------------------------------------------------------FTGK--------------------------G-V--SV--------------A--------------------ILD---------------------------T--------------GIDT-E------H-------------T---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------KDGIS---FV------DNHPDFDDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-L-----------------------AGIVA----AQ-DN-------------------------------EV------------GIT----------------------GI--APN-V--DLYAV---KV---LDKY----------T-NG--K------------YST-------------------------------------V--------VKG--------------I-----------DW---AI--------------------E-----H------N----------I----NI-----------------------------------------VLMSLG---------------G--------------------KK----------------------------ESAFFKEAMDK---------AYQK----GI-----L--------------------------------------------------------------------------------------L---------------IASTG-NE--------GY---------K-----EGNTITY---------------------------------------------------------------------------------------------------------------------------------------P-AKFQ-S---------------------------V---VA---VG--A------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------KN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TR-GFL-----S--S--------R-GDE-L----------------------------------------------------------------------E-----L------M-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-TWK---------------------------------------------------------------------------------------------------------------------D--GNY-RL----------------DSG------TSMAAAHVA----G---------------------------V------------------ASLI----LEKNP---YLSN------EK----------------------------------------------------------------------------------V---------------------REIL-------KKT-----------------------------------------------------------------------------------------------------AIPLGN---AFEYGNGKVNLVDA----------  91
  92 ----------------------------------------------------------GK--------------------------G-V--SV--------------A--------------------ILD---------------------------S--------------GIDT-E------H-------------T---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------KDGIS---FV------ENHPSFDDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-L-----------------------AGIVA----AQ-DN-------------------------------EL------------GMT----------------------GI--APN-V--DLYAV---KV---LDKY----------T-NG--K------------YST-------------------------------------V--------VKG--------------I-----------DW---AI--------------------E-----H------N----------V----NI-----------------------------------------VLMSLG---------------G--------------------KK----------------------------ESAFFKEAMDK---------AYQK----GI-----L--------------------------------------------------------------------------------------L---------------IASAG-NE--------GY---------K-----DGDTISY---------------------------------------------------------------------------------------------------------------------------------------P-AKFQ-S---------------------------V---VA---VG--A------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------KN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AR-GFL-----S--S--------K-GDE-L----------------------------------------------------------------------E-----L------M-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-TWK---------------------------------------------------------------------------------------------------------------------D--GNY-RL----------------DSG------TSMAAAHVV----G---------------------------V------------------ASLI----FEKNP---YLSN------KQ----------------------------------------------------------------------------------V---------------------REIM-------NKA-----------------------------------------------------------------------------------------------------AIPLGN---AFEYGNGKINVDYALN--------  92
  93 ----------------------------------NSETTHKNQDM-------KSV-FTGK--------------------------G-V--SV--------------A--------------------VLD---------------------------T--------------GIDE-D------H-------------K---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I--I-----------------------------------------------------------------------------------KDGIS---FV------ENTPSFDDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-L-----------------------AGIIA----AQ-DN-------------------------------NI------------GTT----------------------GI--APN-V--DLYAV---KV---LDSE----------S-NG--K------------YST-------------------------------------V--------VKG--------------I-----------DW---AI--------------------E-----H------N----------M----NI-----------------------------------------VLMSLG---------------G--------------------TK----------------------------KSLFFEEAMKK---------AYEK----GV-----L--------------------------------------------------------------------------------------L---------------ISSAG-NK--------GF---------R-----EDDTITY---------------------------------------------------------------------------------------------------------------------------------------P-AKFD-S---------------------------V---IA---VG--A------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------ND-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QR-GFL-----S--S--------R-GEN-L----------------------------------------------------------------------E-----L------M-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-TWN---------------------------------------------------------------------------------------------------------------------N--GDY-KY----------------DSG------TSMAAAHVA----G---------------------------A------------------ASLI----FEKNP---YLSN------KK----------------------------------------------------------------------------------V---------------------REIM-------NKT-----------------------------------------------------------------------------------------------------AISLGD---VFEYGNGKINITAAL---------  93
  94 ------------------------------------------EKG-------VSP-LTGK--------------------------G-T--SV--------------A--------------------ILD---------------------------T--------------GIDR-E------H-------------P---------D--------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------KDGIS---FV------ENVSGFDDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-L-----------------------AGIIG----AQ-KN-------------------------------NM------------GMT----------------------GI--APD-T--DLYAV---KV---LDRY----------A-NG--K------------YST-------------------------------------V--------VKG--------------I-----------DW---AI--------------------E-----H------K----------A----NI-----------------------------------------ILMSLG---------------G--------------------KK----------------------------ESVFFEEAMNK---------AYEK----GI-----L--------------------------------------------------------------------------------------L---------------VASAG-NE--------GY---------K-----EGNSITY---------------------------------------------------------------------------------------------------------------------------------------P-AKFD-S---------------------------V---MA---VG--V------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------NK-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QR-GFL-----S--S--------K-GEQ-L----------------------------------------------------------------------E-----V------M-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------WS-TWN---------------------------------------------------------------------------------------------------------------------N--GDY-RL----------------DSG------TSMAAAHVV----G---------------------------V------------------ASLL----LEKDR---MMSN------QK----------------------------------------------------------------------------------L---------------------RALL-------KKS-----------------------------------------------------------------------------------------------------ATPLGN---PFEYGNGKVDISHA----------  94
  95 --------------------------------------------------IKNKYKLDGE--------------------------G-V--SI--------------A--------------------ILD---------------------------S--------------GIST-KMNFLPIEESVSFVNEPNTTVN---------D--------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TY-N-----------------------TGIIN-------------------------------------------------------------------------------AI--APK-A--KLYIV---KV---LNKEL-KGN------------------------YTN-------------------------------------I--------TKG--------------I-----------EW--------------------------------------S----------IKNDVDI-----------------------------------------ISMSLGGDSYSKELHA---------------------------------------------------------------AIKK---------AYNK----GI-----I--------------------------------------------------------------------------------------L---------------TSSVG-NKGISNLDTVSY-------------------------------------------------------------------------------------------------------------------------------------------------------------PAKFNE-----------------------------V---IG---VG--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSHDDRLFS--S--------SKGQGIT----------------------------------------------------------------------------I------M-----------------A-----P-------------G-----------------EN--------------------------------L------------------------------------------------------------------KS-----------------------------------------------------------------------------------------------------------------------------------------YSINSDYYKTSG------TSVSNAYVS----G---------------------------A------------------LALL----FQ--------------------------------------------------------------------------------------------------------------------------FEDFNITNEDIINT----------------------------------------------------------------------------------------------------VKKSAYSKGSRFEYGYGIFDLEEAIK--------  95
  96 --------------------------------QWNLEPIQVEQAW-------KAG-LTGK--------------------------D-V--KI--------------A--------------------VID---------------------------S--------------GI-S-P------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--I-----------------------------------------------------------------------------------AGGFS---AV------SYTSSYKDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----AK-HN-------------------------------GY------------GID----------------------GI--APE-A--QIYAV---KA---LDQN----------G-SG--D------------LQG-------------------------------------L--------LQG--------------I-----------DW---SI--------------------A-----N------G----------M----DI-----------------------------------------VNMSLG---------------T--------------------TS----------------------------DSQILHDAMDK---------AYEQ----GV-----L--------------------------------------------------------------------------------------L---------------VAASG-ND--------GN---------G-------KPVNY---------------------------------------------------------------------------------------------------------------------------------------P-AAYS-S---------------------------V---VA---VS--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------EK-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QL-ASF-----S--T--------T-GDE-V----------------------------------------------------------------------E-----F------S-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------TS-TYL---------------------------------------------------------------------------------------------------------------------N--QFY-AT----------------GSG------TSQATPHAA----A---------------------------M------------------FALL----KQRDP---AETN------VQ----------------------------------------------------------------------------------L---------------------RADM-------QKN-----------------------------------------------------------------------------------------------------IVDLGTTGRDQQFGYGFIQY-------------  96
  97 ------------ADSTDFKVLSDGTDTSDNFEQWNLEPIQVKQAW-------KAG-LTGK--------------------------N-V--KI--------------A--------------------VID---------------------------S--------------GI-S-P------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--I-----------------------------------------------------------------------------------AGGYS---AV------SYTSSYKDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----AK-HN-------------------------------GY------------GID----------------------GI--APE-A--QVYAV---KA---LDQN----------G-SG--D------------LQG-------------------------------------L--------LQG--------------I-----------DW---SI--------------------T-----H------G----------M----DI-----------------------------------------VNMSLG---------------T--------------------TS----------------------------DSKILHDAVDK---------AYEQ----GI-----L--------------------------------------------------------------------------------------L---------------VAASG-ND--------GN---------G-------KPVNY---------------------------------------------------------------------------------------------------------------------------------------P-AAYS-S---------------------------V---VA---VS--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------EK-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QL-ASF-----S--T--------T-GDE-V----------------------------------------------------------------------E-----F------S-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------TS-TYL---------------------------------------------------------------------------------------------------------------------N--QYY-AT----------------GSG------TSQATPHAA----A---------------------------M------------------FALL----KQRNP---AETN------VQ----------------------------------------------------------------------------------L---------------------RADM-------QKH-----------------------------------------------------------------------------------------------------IVDLGTAGRDQQFGYGLIQYKARA---------  97
  98 ---------------------SDGTDTSDNFEQWNLEPIQVKQAW-------KAG-LTGK--------------------------N-I--KI--------------A--------------------VID---------------------------S--------------GI-S-P------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--I-----------------------------------------------------------------------------------AGGYS---AV------SYTSSYKDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----AK-HN-------------------------------GY------------GID----------------------GI--APE-A--QIYAV---KA---LDQN----------G-SG--D------------LQS-------------------------------------L--------LQG--------------I-----------DW---SI--------------------A-----N------R----------M----DI-----------------------------------------VNMSLG---------------T--------------------TS----------------------------DSKILHDAVNK---------AYEQ----GV-----L--------------------------------------------------------------------------------------L---------------VAASG-ND--------GN---------G-------KPVNY---------------------------------------------------------------------------------------------------------------------------------------P-AAYS-S---------------------------V---VA---VS--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------EK-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QL-ASF-----S--T--------T-GDE-V----------------------------------------------------------------------E-----F------S-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------TS-TYL---------------------------------------------------------------------------------------------------------------------N--QYY-AT----------------GSG------TSQATPHAA----A---------------------------M------------------FALL----KQRDP---AETN------VQ----------------------------------------------------------------------------------L---------------------REEM-------RKN-----------------------------------------------------------------------------------------------------IVDLGTAGRDQQFGYGLIQYKAQAT--------  98
  99 ---------------------------------WDIEPTQVKQAW-------KEG-LTGK--------------------------K-V--KV--------------A--------------------VID---------------------------S--------------GI-Y-P------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--I-----------------------------------------------------------------------------------AGGYS---AV------SYTSSYKDD---N----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----AK-HD-------------------------------GY------------GID----------------------GI--APD-V--RLYAV---KA---LDRK----------G-AG--D------------LKS-------------------------------------L--------LKA--------------I-----------DW---SI--------------------A-----N------K----------M----DI-----------------------------------------INMSLG---------------T--------------------NA----------------------------DSKILHDAVDK---------AYKK----GI-----V--------------------------------------------------------------------------------------I---------------VAAAG-ND--------GN---------K-------KPVNY---------------------------------------------------------------------------------------------------------------------------------------P-GAYS-S---------------------------V---TA---VS--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ET-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL-AAF-----S--T--------T-GKQ-I----------------------------------------------------------------------E-----F------A-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------TS-TYL---------------------------------------------------------------------------------------------------------------------N--QMY-AT----------------ADG------TSQAAPHVT----G---------------------------M------------------FALL----KQKYP---EETN------TQ----------------------------------------------------------------------------------L---------------------RQQM-------QQN-----------------------------------------------------------------------------------------------------VKDLGAPGRDSQFGYGLVQY-------------  99
 100 AQSTP-W-------GVTRVQA---------------PNV-----W-------NRG-FTGS--------------------------G-V--RV--------------A--------------------VLD---------------------------T--------------GIHS-S------H-------------E---------D--------------------------------L--------------------------------------------------------------------------------------------TVS----------------------------------------------------------------------------------------------------------------------------------GG------YS--V-----FGDS---P------------YN-----------------------------------------------------------------------------------------D---V---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AR--N-------------------------------NS------------VGV--I-------------------GV--AYN-A--QLYAV---KV---LNNQ----------G-SG--T------------LAG-------------------------------------I--------AQG--------------I-----------EW---AR----------QNN-------------------------------M----HV-----------------------------------------INMSLG-------G-TSG---S---------------------T--------------------------TLQN-----AVNA-A--------YNA----GI-----L--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GN---------SAGTGD---NVGF---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----PN---------------------A---MA---VA--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------GN-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------T-G---P--------------------AV------------------------------------------------E-----I------A-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------NS-TYP--------------------------------------------------------------------------------------------------------T-------N--------TY-RS----------------LNG------TSMAAPHVA----G---------------------------V------------------AA-L----LK----S-------AR-PAV-------------------------------------------------------------T---AAG--------------I---------------------RNAM-------NST-------------------------AL------------------------------------------------------------------------N-------------L--GNSNWYGNGLVRANNALD 100
 101 AQTVP-W-------GVPHVQG---------------TDA-----H-------AAG-HTGS--------------------------G-V--KV--------------A--------------------ILD---------------------------T--------------GIDR-N------H-------------E---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------HSV-F-----TDSANRDP------------YY-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------VGV--L-------------------GV--AYN-A--ELYAV---KV---LNNS----------G-SG--S------------YAG-------------------------------------I--------AEG--------------I-----------EW---AV----------NNG-------------------------------M----DI-----------------------------------------INMSLG-------G-SMS---S---------------------S--------------------------ILEE-----WCNI-A--------YNS----GV-----L--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GR---------TNGRGD---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----DS---------------------V---IA---VA--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------T-G---P--------------------AV------------------------------------------------E-----I------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-TTP--------------------------------------------------------------------------------------------------------G-------N--------SY-AS----------------YNG------TSMASPHVA----G---------------------------V------------------AA-L----VL----A-------AN-PNL-------------------------------------------------------------S---NVE--------------L---------------------RNRL-------NDT-------------------------AQ------------------------------------------------------------------------N-------------L--GDANHFGNGLVRAVDAIN 101
 102 -QTVP-W-------GISFINT---------------QQA-----H-------NRG-IFGN--------------------------G-A--RV--------------A--------------------VLD---------------------------T--------------GI-A-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------RIA----------------------------------------------------------------------------------------------------------------------------------GG------ASF-I-----SSEP---S------------YH-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--DLYAV---KV---LDRN----------G-SG--S------------LAS-------------------------------------V--------AQG--------------I-----------EW---AI----------NNN-------------------------------M----HI-----------------------------------------INMSLG-------S-TSG---S---------------------S--------------------------TLEL-----AVNR-A--------NNA----GI-----L--------------------------------------------------------------------------------------L---------------VGAAG-NT--------GR---------Q-G-------VNY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----SG---------------------V---MA---VA--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NG-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--T--------Y-G---P--------------------EI------------------------------------------------E-----I------S-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------NS-TYT--------------------------------------------------------------------------------------------------------G-------N--------RY-VS----------------LSG------TSMATPHVA----G---------------------------V------------------AA-L----VK----S-------RY-PSY-------------------------------------------------------------T---NNQ--------------I---------------------RQRI-------NQT-------------------------AT------------------------------------------------------------------------Y-------------L--GSPSLYGNGLVHAGRATQ 102
 103 AQTVP-W-------GIPYIYS---------------DVV-----H-------RQG-YFGN--------------------------G-V--KV--------------A--------------------VLD---------------------------T--------------GV-A-P------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------HIR----------------------------------------------------------------------------------------------------------------------------------GG------VSF-I-----STEN---T------------YV-----------------------------------------------------------------------------------------D---Y---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------YGV--L-------------------GV--APG-A--ELYAV---KV---LDRN----------G-SG--S------------HAS-------------------------------------I--------AQG--------------I-----------EW---AM----------NNG-------------------------------M----DI-----------------------------------------ANMSLG-------S-PSG---S---------------------T--------------------------TLQL-----AADR-A--------RNA----GV-----L--------------------------------------------------------------------------------------L---------------IGAAG-NS--------GQ---------Q-GGSN---NMGY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AS---------------------V---MA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NG-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ANF-----S--S--------Y-G---S--------------------EL------------------------------------------------E-----I------M-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------NS-TYL--------------------------------------------------------------------------------------------------------N-------N--------GY-RS----------------LNG------TSMASPHVA----G---------------------------V------------------AA-L----VK----Q-------KH-PHL-------------------------------------------------------------T---AAQ--------------I---------------------RNRM-------NQT-------------------------AI------------------------------------------------------------------------P-------------L--GNSTYYGNGLVDAEYAAQ 103
 104 AQSVP-W-------GISRVQA---------------PAA-----H-------NRG-LTGS--------------------------G-V--KV--------------A--------------------VLD---------------------------T--------------GI-S-T------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NIR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PGEP---S------------TQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--ELYAV---KV---LGAS----------G-SG--S------------VSS-------------------------------------I--------AQG--------------L-----------EW---AG----------NNG-------------------------------M----HV-----------------------------------------ANLSLG-------S-PSP---S---------------------A--------------------------TLEQ-----AVNS-A--------TSR----GV-----L--------------------------------------------------------------------------------------V---------------VAASG-NS--------GA---------G--------SISY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AN---------------------A---MA---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--Q--------Y-G---A--------------------GL------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------QS-TYP--------------------------------------------------------------------------------------------------------G-------S--------TY-AS----------------LNG------TSMATPHVA----G---------------------------A------------------AA-L----VK----Q-------KN-PSW-------------------------------------------------------------S---NVQ--------------I---------------------RNHL-------KNT-------------------------AT------------------------------------------------------------------------S-------------L--GSTNLYGSGLVNAEAATR 104
 105 AQSVP-W-------GISRVQA---------------PAA-----H-------NRG-LTGS--------------------------G-V--KV--------------A--------------------VLD---------------------------T--------------GI-S-T------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NIR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PGEP---S------------TQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APN-A--ELYAV---KV---LGAS----------G-SG--S------------VSS-------------------------------------I--------AQG--------------L-----------EW---AG----------NNG-------------------------------M----HV-----------------------------------------ANLSLG-------S-PSP---S---------------------A--------------------------TLEQ-----AVNS-A--------TSR----GV-----L--------------------------------------------------------------------------------------V---------------VAASG-NS--------GA---------G--------SISY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AN---------------------A---MA---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--Q--------Y-G---A--------------------GL------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------QS-TYP--------------------------------------------------------------------------------------------------------G-------S--------TY-AS----------------LNG------TSMATPHVA----G---------------------------A------------------AA-L----VK----Q-------KN-PSW-------------------------------------------------------------S---NVQ--------------I---------------------RNHL-------KNT-------------------------AT------------------------------------------------------------------------S-------------L--GSTNLYGSGLVNAEAATR 105
 106 AQSVP-W-------GISRVQA---------------PAA-----H-------NRG-LTGS--------------------------G-V--KV--------------A--------------------VLD---------------------------T--------------GI-S-T------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NIR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PGEP---S------------TQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--ELYAV---KV---LGAS----------G-SG--S------------VSS-------------------------------------I--------AQG--------------L-----------EW---AG----------NNG-------------------------------M----HV-----------------------------------------ANLSLG-------S-PSP---S---------------------A--------------------------TLEQ-----AVNS-A--------TSR----GV-----L--------------------------------------------------------------------------------------V---------------VAASG-NS--------GA---------G--------SISY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AN---------------------A---MA---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--Q--------Y-G---A--------------------GL------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------QS-TYP--------------------------------------------------------------------------------------------------------G-------S--------TY-AS----------------LNG------TSMATPHVA----G---------------------------V------------------AA-L----VK----Q-------KN-PSW-------------------------------------------------------------S---NVQ--------------I---------------------RNHL-------KNT-------------------------AT------------------------------------------------------------------------G-------------L--GNTNLYGSGLVNAEAATR 106
 107 -QTVP-W-------GINRVQA---------------PIA-----Q-------SRG-FTGT--------------------------G-V--RV--------------A--------------------VLD---------------------------T--------------GI-S-N------H-------------A---------D--------------------------------L--------------------------------------------------------------------------------------------RIR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PGEP---N------------IS-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APN-V--DLYGV---KV---LGAS----------G-SG--S------------ISG-------------------------------------I--------AQG--------------L-----------QW---AA----------NNG-------------------------------M----HI-----------------------------------------ANMSLG-------S-SAG---S---------------------A--------------------------TMEQ-----AVNQ-A--------TAS----GV-----L--------------------------------------------------------------------------------------V---------------VAASG-NS--------GA---------G--------NVGF---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AN---------------------A---MA---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ATF-----S--Q--------Y-G---A--------------------GL------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------QS-TVP--------------------------------------------------------------------------------------------------------G-------N--------GY-AS----------------FNG------TSMATPHVA----G---------------------------V------------------AA-L----VK----Q-------KN-PSW-------------------------------------------------------------S---NVQ--------------I---------------------RNHL-------KNT-------------------------AT------------------------------------------------------------------------N-------------L--GNTTQFGSGLVNAEAATR 107
 108 NQVTP-W-------GITRVQA---------------PTA-----W-------TRG-YTGT--------------------------G-V--RV--------------A--------------------VLD---------------------------T--------------GI-S-T------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NIR----------------------------------------------------------------------------------------------------------------------------------GG------VSF-V-----PGEP---S------------YQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--V-------------------GV--APN-A--ELYAV---KV---LGAN----------G-SG--S------------VSS-------------------------------------I--------AQG--------------L-----------QW---TA----------QNN-------------------------------I----HV-----------------------------------------ANLSLG-------S-PVG---S---------------------Q--------------------------TLEL-----AVNQ-A--------TNA----GV-----L--------------------------------------------------------------------------------------V---------------VAATG-NN--------GS---------G--------TVSY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----AN---------------------A---LA---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--Q--------Y-G---T--------------------GL------------------------------------------------N-----I------V-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------QS-TYP--------------------------------------------------------------------------------------------------------G-------N--------RY-AS----------------LSG------TSMATPHVA----G---------------------------V------------------AA-L----VK----Q-------KN-PSW-------------------------------------------------------------S---NTQ--------------I---------------------RQHL-------TST-------------------------AT------------------------------------------------------------------------S-------------L--GNSNQFGSGLVNAEAATR 108
 109 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--SLYAV---KV---LDST----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PTG---S---------------------T--------------------------ALKT-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSTS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GNSFYYGKGLINVQAAAQ 109
 110 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--SLYAV---KV---LDST----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PTG---S---------------------T--------------------------ALKT-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSTS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GNSFYYGKGLINVQAAAQ 110
 111 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--SPS-A--SLYAV---KV---LDST----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------T--------------------------ALKT-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GNSFYYGKGLINVQAAAQ 111
 112 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--SPS-A--SLYAV---KV---LDST----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------T--------------------------ALKT-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GNSFYYGKGLINVQAAAQ 112
 113 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-S--ALYAV---KV---LDST----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PTG---S---------------------T--------------------------ALKT-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSTS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------AN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GSSFYYGKGLINVQAAAQ 113
 114 AQSVP-Y-------GISQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSETN--P------------YQ-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AL--N-------------------------------NS------------IGV--L-------------------GV--APN-A--SLYAV---KV---LDST----------G-NG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------T--------------------------ALKT-----VVDK-A--------VSN----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSTS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---P--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TS-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------A---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------L--GSSFYYGKGLINVQAC-- 114
 115 --------------------------------------------H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------KVS----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PSEPN--P------------FQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------VGV--L-------------------GV--APS-A--SLYAV---KV---LSSS----------G-SG--D------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------SNN-------------------------------M----DV-----------------------------------------INMSLG-------G-PQG---S---------------------T--------------------------ALKA-----VVDK-A--------VSQ----GI-----V--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GS---------S-GSTS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------V---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------S--------SY-GS----------------YNG------TSMASPHVA----G---------------------------A------------------AA-L----VL----S-------KH-PNW-------------------------------------------------------------T---NSQ--------------V---------------------RNSL-------EST-------------------------AT------------------------------------------------------------------------N-------------L--GNSFYYGKGLINVQAAA- 115
 116 --------------------------------------L-----H-------SQG-YTGS--------------------------N-D--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVR----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----PFGTN--P------------YQ-----------------------------------------------------------------------------------------G---R---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AS--F-------------------------------TS------------SGV--L-------------------GV--PPS-A--SSYPS---KA---HSSS----------Q-SA--A------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------PHN-------------------------------M----YF-----------------------------------------SNMSLG-------G-PSG---S---------------------T--------------------------AQET-----VVDK-A--------VSS----GI-----V--------------------------------------------------------------------------------------V---------------AAAAG-NE--------GS---------S-GSSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----PS---------------------T---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------A-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------G--------TY-GA----------------YNG------TSMATPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PTW-------------------------------------------------------------T---NAQ--------------V---------------------RDRL-------EST-------------------------AT------------------------------------------------------------------------Y-------------H--GNSFYYGKGL-------- 116
 117 AQSVP-Y-------GVSQIKY---------------PAL-----H-------SQG-FTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------S---------D--------------------------------L--------------------------------------------------------------------------------------------KVA----------------------------------------------------------------------------------------------------------------------------------GG------ASM-V-----PSETN--P------------FQ-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--SLYAV---KV---LGAD----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------ANN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------A--------------------------ALKA-----AVDK-A--------VAS----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NE--------GT---------S-GGSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-G--K-Y----PS---------------------V---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------N--------KY-GA----------------YNG------TSMASPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PNW-------------------------------------------------------------T---NTQ--------------V---------------------RSSL-------ENT-------------------------TT------------------------------------------------------------------------K-------------L--GDAFYYKKGLINVQAAAQ 117
 118 AQSVP-Y-------GVSQIKA---------------PAL-----H-------SQG-FTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------KVA----------------------------------------------------------------------------------------------------------------------------------GG------ASM-V-----PSETN--P------------FQ-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------VGV--L-------------------GV--APS-A--SLYAV---KV---LGAD----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------ANN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------A--------------------------ALKA-----AVDK-A--------VAS----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NE--------GT---------S-GGSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-G--K-Y----PS---------------------V---IA---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---S--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------N--------KY-GA----------------YNG------TSMASPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PNW-------------------------------------------------------------T---NTQ--------------V---------------------RSSL-------ENT-------------------------TT------------------------------------------------------------------------K-------------L--GDAFYYGKGLINVQAAAQ 118
 119 AQSVP-Y-------GVSQIKA---------------PAL-----H-------SQG-YTGS--------------------------N-V--KV--------------A--------------------VID---------------------------S--------------GIDS-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------KVA----------------------------------------------------------------------------------------------------------------------------------GG------ASM-V-----PSETN--P------------FQ-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTVA----AL--N-------------------------------NS------------IGV--L-------------------GV--APS-A--SLYAV---KV---LGAD----------G-SG--Q------------YSW-------------------------------------I--------ING--------------I-----------EW---AI----------ANN-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------A--------------------------ALKA-----AVDK-A--------VAS----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NE--------GT---------S-GSSS---TVGY---------------------------------------------------------------------------------------------------------------------------------------P-G--K-Y----PS---------------------V---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---P--------------------EL------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------QS-TLP--------------------------------------------------------------------------------------------------------G-------N--------KY-GA----------------YNG------TSMASPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PNW-------------------------------------------------------------T---NTQ--------------V---------------------RSSL-------ENT-------------------------TT------------------------------------------------------------------------K-------------L--GDSFYYGKGLINVQAAAQ 119
 120 AQTVP-Y-------GIPLIKA---------------DKV-----Q-------AQG-YKGA--------------------------N-V--KV--------------G--------------------IID---------------------------T--------------GIAA-S------H-------------T---------D--------------------------------L--------------------------------------------------------------------------------------------KVV----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----SGESY--N-------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVA----AL--D-------------------------------NT------------TGV--L-------------------GV--APN-V--SLYAI---KV---LNSS----------G-SG--T------------YSA-------------------------------------I--------VSG--------------I-----------EW---AT----------QNG-------------------------------L----DV-----------------------------------------INMSLG-------G-PSG---S---------------------T--------------------------ALKQ-----AVDK-A--------YAS----GI-----V--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GS---------S-GSQN---TIGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----DS---------------------V---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NK-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---A--------------------EL------------------------------------------------E-----V------M-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------YS-TYP--------------------------------------------------------------------------------------------------------S-------N--------TY-TS----------------LNG------TSMASPHVA----G---------------------------A------------------AA-L----IL----S-------KY-PTL-------------------------------------------------------------S---ASQ--------------V---------------------RNRL-------SST-------------------------AT------------------------------------------------------------------------N-------------L--GDSFYYGKGLINVEAAAQ 120
 121 AQTVP-Y-------GIPLIKA---------------DKV-----Q-------AQG-FKGA--------------------------N-V--KV--------------A--------------------VLD---------------------------T--------------GIQA-S------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------NVV----------------------------------------------------------------------------------------------------------------------------------GG------ASF-V-----AGEAY--N-------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVA----AL--D-------------------------------NT------------TGV--L-------------------GV--APS-V--SLYAV---KV---LNSS----------G-SG--T------------YSG-------------------------------------I--------VSG--------------I-----------EW---AT----------TNG-------------------------------M----DV-----------------------------------------INMSLG-------G-PSG---S---------------------T--------------------------AMKQ-----AVDN-A--------YAR----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GS---------S-GNTN---TIGY---------------------------------------------------------------------------------------------------------------------------------------P-A--K-Y----DS---------------------V---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NS-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--S--------V-G---A--------------------EL------------------------------------------------E-----V------M-----------------A-----P-------------G-----------------AG--------------------------------V------------------------------------------------------------------YS-TYP--------------------------------------------------------------------------------------------------------T-------S--------TY-AT----------------LNG------TSMASPHVA----G---------------------------A------------------AA-L----IL----S-------KH-PNL-------------------------------------------------------------S---ASQ--------------V---------------------RNRL-------SST-------------------------AT------------------------------------------------------------------------Y-------------L--GSSFYYGKGLINVEAAAQ 121
 122 -----------------------------------------------------QG-YKGS--------------------------N-I--KI--------------G--------------------IID---------------------------S--------------GIDI-T------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--V-----------------------------------------------------------------------------------TDGIN---II------DPNSNYNDD---Y----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-V-----------------------AGVIS----AL-DN-------------------------------NK------------GVL----------------------GM--APL-S--EIYAI---KV---LDAR----------G-KG--S------------ISN-------------------------------------V--------ISG--------------I-----------EW---AI--------------------D-----N------K----------L----DI-----------------------------------------VNLSLQ---------------T--------------------II----------------------------NNNALEEVVKK---------AYEQ----GI-----I--------------------------------------------------------------------------------------L---------------VAAAG-NK--------GH---------N----GVQETITY---------------------------------------------------------------------------------------------------------------------------------------P-AAYK-E---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------EN-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EK-VIF-----S--S--------V-GSR-L----------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------NN--------------------------------V------------------------------------------------------------------YT-TIP---------------------------------------------------------------------------------------------------------------------R--SFY-YV----------------YSG------TSIASPHVA----G---------------------------I------------------AALL----KEANP---NLTN------IE----------------------------------------------------------------------------------I---------------------SQIL-------KDT-----------------------------------------------------------------------------------------------------ATDLKD---NFYYGNGLVNAEKA---------- 122
 123 -----------------------------------------------------QG-YKGS--------------------------N-I--KI--------------G--------------------IID---------------------------S--------------GIDI-T------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--V-----------------------------------------------------------------------------------TDGIN---II------DPNSNYNDD---Y----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-V-----------------------AGVIS----AL-DN-------------------------------NK------------GVL----------------------GM--APL-S--EIYAI---KV---LDAR----------G-KG--S------------ISN-------------------------------------V--------ISG--------------I-----------EW---AI--------------------D-----N------K----------L----DI-----------------------------------------VNLSLQ---------------T--------------------II----------------------------NNNALEEVVKK---------AYEQ----GI-----I--------------------------------------------------------------------------------------L---------------VAAAG-NK--------GH---------N----GVQETITY---------------------------------------------------------------------------------------------------------------------------------------P-AAYK-E---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------EN-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EK-VIF-----S--S--------V-GSR-L----------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------NN--------------------------------V------------------------------------------------------------------YT-TIP---------------------------------------------------------------------------------------------------------------------R--SFY-YV----------------YSG------TSIASPHVA----G---------------------------I------------------AALL----KEANP---NLTN------IE----------------------------------------------------------------------------------I---------------------SQIL-------KDT-----------------------------------------------------------------------------------------------------ATDLKD---NFYYGNGLVNAEKA---------- 123
 124 ----------------------------------------------------KQG-YKGS--------------------------N-I--KI--------------G--------------------IID---------------------------S--------------GIDI-T------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--V-----------------------------------------------------------------------------------TGGIN---II------DPNSNYNDD---F----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-V-----------------------AGVIA----AL-DN-------------------------------NK------------GVL----------------------GM--APL-S--EIYAI---KV---LDAR----------G-KG--S------------ISN-------------------------------------V--------ISG--------------I-----------EW---AI--------------------D-----N------K----------L----DI-----------------------------------------VNLSLQ---------------T--------------------II----------------------------NNNALEEIVKK---------AYEQ----GI-----I--------------------------------------------------------------------------------------L---------------VAAAG-NK--------GH---------N----GAQETITY---------------------------------------------------------------------------------------------------------------------------------------P-AAYK-E---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------EN-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EK-VIF-----S--S--------V-GSR-L----------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------NN--------------------------------V------------------------------------------------------------------YT-TIP---------------------------------------------------------------------------------------------------------------------R--SFY-YV----------------YSG------TSIASPHVA----G---------------------------I------------------AALL----KESNP---NLTN------IE----------------------------------------------------------------------------------L---------------------SQIL-------KDT-----------------------------------------------------------------------------------------------------ATDLKD---NFYYGNGLVNAEKA---------- 124
 125 -------------------------------------INAPAAW--------EKS-EKGK--------------------------D-V--VV--------------A--------------------VLD---------------------------T--------------GCQI-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IEGRN--------------------------------------------------------FTTD------------------------------NNSD------PNNYT----------------DMNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------Q-----GV------------------------------------LGV--APQ-A--KLLIV---KV---L---------GGPNG-SG--A------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLSGKEDNPEL-HQAVINA-------------VNN--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------GGDNNQNTDELSY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYQE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DL---------------------------NKKIAVF-----S--ESNKNV--------------------------------------------------------------------------------D-----L------V-----------------G-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYK---------G-GGY--ATLSG------TSMATPHIS----G---------------------------G------------------AALI----IKHCESNKEFDRTLSEDEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TAL-V-------DSKRLVGNGLLDLAK----------- 125
 126 -------------------------------PEGVKLINAPAAW--------EKS-EKGK--------------------------D-V--VV--------------A--------------------VLD---------------------------T--------------GCQI-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTTD------------------------------NNSD------PNNYT----------------DMNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------Q-----GV------------------------------------LGV--APQ-A--KLLIV---KV---L---------GGPRG-SG--A------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLGGPQDVPEL-HQAVINA-------------VNN--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------SGDGSGEIDEFEY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYPE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF---------------------------NKKTPRF-----T--VSNKNV--------------------------------------------------------------------------------D-----L------V-----------------G-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYK---------G-GGY--ATLSG------TSMATPHIS----G---------------------------G------------------AALI----IKHCESENEFGRTLSEDEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TAL-T-------ESKRLVGNGLLDLA------------ 126
 127 ---------------------------------GVQLINAPAAW--------GKS-EKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCQI-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTTD------------------------------NNSD------SNNYS----------------DMNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------K-----GV------------------------------------LGV--APQ-A--KLLIV---KV---L---------GGPNG-SG--A------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLGGPQDVPEL-HQAVKNA-------------VNN--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------EGDNSGNTDEFGY---------------------------------------------------------------------------------------------------------------------------------------------------PGSYPE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DM---------------------------NKKVASF-----S--NTNKNV--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------YS-----------------------------------------------------------------------------------------------------------------------------TYK---------D-GRY--AKLNG------TSMATPHIS----G---------------------------G------------------AALI----IKHCESKNEFDRTLSEDEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TAL-N-------YPKRSVGNGLLDLAK----------- 127
 128 ----------------------------------VKFINAPAVW--------EKS-EKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCQT-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGKN--------------------------------------------------------FTTD------------------------------NNSD------PNNFS----------------DLNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------K-----GV------------------------------------LGV--APQ-A--KLLIV---KV---L---------GGPNG-SG--A------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLGGPQDVPEL-HQAVKNA-------------VNN--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------GGDNNSNTDEFDY---------------------------------------------------------------------------------------------------------------------------------------------------PGSYQE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF---------------------------NKKIAPF-----S--DSNKNV--------------------------------------------------------------------------------D-----L------V-----------------G-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYK---------G-GGY--ATLSG------TSMATPHIS----G---------------------------G------------------SALI----IKLCESKQEFDRTLSEDEVY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TPL-A-------ESKRLVGNGLLDLAK----------- 128
 129 -------------------------------------INAPAAW--------EKS-EKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCQT-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGKN--------------------------------------------------------FTTD------------------------------NNSD------PNNYS----------------DLNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------Q-----GV------------------------------------LGV--APQ-A--KLLIV---KI---L---------AG-NG-KG--S------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLSGQEDNPDL-HQAVKNA-------------VNN--------------------------------------------------------------DI-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------GG---HQTDMLSY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYQE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL---------------------------NKKIAIF-----S--ESNKNV--------------------------------------------------------------------------------D-----L------V-----------------G-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYK---------G-GGY--ATLSG------TSMATPHIS----G---------------------------G------------------SALI----IKLCESKQEFDRTLSEDEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TPL-A-------DSKRLVGNGLLDLAK----------- 129
 130 ---------------------------------GVQLINAPAAW--------EKG-EKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCQI-D------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IEGKN--------------------------------------------------------FTAD------------------------------NNSD------PNNYS----------------DMNGHG-------TH-V-----------------------AGTIA----ATENN-------------------------Q-----GV------------------------------------LGV--APQ-S--KLLIV---KV---L---------GGPNG-SG--A------------YEW-------------------------------------I--------IDG--------------I-----------NY--------------------------------------AVNWRGPNGEKV----RV-----------------------------------------ISMSLSGPNDVPEL-HQAVKNA-------------VNN--------------------------------------------------------------EI-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------SGDNNHTTDEKSY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYQE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DL---------------------------NKKIAPF-----S--ESNKNV--------------------------------------------------------------------------------D-----L------V-----------------G-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------YS-----------------------------------------------------------------------------------------------------------------------------TYK---------N-GTY--AKLSG------TSMATPHIS----G---------------------------G------------------AALI----IKHCESKNEFDRTLSEDEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------AAL-D-------DSKQSVGNGLLDLAK----------- 130
 131 ---------------------------VHEIPEGVQLINAPVAW--------DKS-EKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------I--------------GCQS-D------H-------------I---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTTD------------------------------DNSN------PDNYL----------------DLNGHG-------TH-V-----------------------SGTIA----ATENN-------------------------K-----GV------------------------------------LGV--APQ-A--KLLIV---KV---L---------GGPDG-SG--V------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVSWRGPNGEKV----RV-----------------------------------------ISMSLGGPYDVPEL-HQAVKNA-------------VNN--------------------------------------------------------------GI-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------EGDNNGNTDEFGY---------------------------------------------------------------------------------------------------------------------------------------------------PGCYPE-----------------------------V---VE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DL---------------------------EKKVATF-----S--NTNKNV--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYI---------G-GGY--AKLSG------TSMATPHIS----G---------------------------G------------------AALI----IKHCENKNEFDRTLSENEIY--------------------------------------------------------------------------------------------------------AQLI-------RRT------------------------------------------------------------------------------------------------TTL-N-------YSKRSVGNGVLDLAKE---------- 131
 132 ----------------------------------VQLIHAPGAW--------EKS-AKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCDI-N------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTED------------------------------YEGD------PKVYL----------------DNNGHG-------TH-V-----------------------AGTIA----AAENG-------------------------V-----GV------------------------------------LGV--APL-A--KLLVL---KV---L---------SG-DG-SG--S------------YQQ-------------------------------------I--------IEA--------------I-----------DY--------------------------------------AVRWRGPNQERV----RI-----------------------------------------ISMSLGGPQDVPEL-HEVIQHA-------------VKQ--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------NGDCSDETEELDF---------------------------------------------------------------------------------------------------------------------------------------------------PGAYSE-----------------------------V---IE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL---------------------------ERKLACF-----S--NSNQEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYP---------E-GKY--AVLSG------TSMATPHIA----G---------------------------A------------------LALL----IKQCE--REYGRKLSEPEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------VPL-G-------YERTSEGNGLIDLLK----------- 132
 133 ----------------------------------VQLIHAPGAW--------EKS-AKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCDI-N------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTED------------------------------YEGD------PKIYL----------------DNNGHG-------TH-V-----------------------AGTIA----AAENG-------------------------V-----GV------------------------------------LGV--APL-A--KLLVL---KV---L---------SG-DG-SG--S------------YQQ-------------------------------------I--------IEA--------------I-----------DY--------------------------------------AVRWRGPNQERV----RI-----------------------------------------ISMSLGGPQDVPEL-HEVIQHA-------------VKQ--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------NGDCSDETEELDF---------------------------------------------------------------------------------------------------------------------------------------------------PGAYSE-----------------------------V---IE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL---------------------------ERKLACF-----S--NSNQEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYP---------E-GKY--AVLSG------TSMATPHIA----G---------------------------A------------------LALL----IKQCE--REYGRKLSEPEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------VPL-G-------YERTSEGNGLIDLLK----------- 133
 134 ----------------------------NEIPPGVQLIHAPEIW--------EKS-EKGN--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCDV-N------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTED------------------------------YGND------PNNYL----------------DNNGHG-------TH-V-----------------------AGTIA----ATEND-------------------------I-----GV------------------------------------LGV--APL-A--KLLVL---KV---L---------AG-DG-SG--N------------YQH-------------------------------------I--------IDA--------------I-----------DY--------------------------------------AISWRGPNQERV----RI-----------------------------------------ISMSLGGPEDVPEL-HEVIQKA-------------VKQ--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------SGDCNDRTEELDF---------------------------------------------------------------------------------------------------------------------------------------------------PGAYSE-----------------------------V---IE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL---------------------------ERKLACF-----S--NSNQEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYP---------G-GKY--AVLSG------TSMATPHIS----G---------------------------A------------------LALL----IKQCE--REYGRRLSEPEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------VPL-G-------YERTSEGNGLIDLVKE---------- 134
 135 ----------------------------------VQMIHAPQVW--------EKS-VKGQ--------------------------D-V--VV--------------A--------------------VLD---------------------------T--------------GCDT-N------H-------------I---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IDGRN--------------------------------------------------------FTKD------------------------------YEAD------PNVYL----------------DNNGHG-------TH-V-----------------------AGTIA----ATENG-------------------------V-----GV------------------------------------LGV--APL-A--KMLVL---KV---L---------AG-DG-SG--S------------YEQ-------------------------------------I--------IEA--------------I-----------HY--------------------------------------AVNWRGPNQEKV----RI-----------------------------------------ISMSLGGPQDVPEL-HEAIQNA-------------VKQ--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------NGDCDDETEELDF---------------------------------------------------------------------------------------------------------------------------------------------------PGAYSE-----------------------------V---IE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL---------------------------ERKIACF-----S--NSNQEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------DE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYP---------D-GKY--AVLSG------TSMATPHIA----G---------------------------A------------------LALL----IKQCE--KEYGRKLSEPEVY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------VPL-G-------YERTSEGNGLIDLLK----------- 135
 136 ---------------------------VNEIPPGVQLIHAPQVW--------EKS-AKGK--------------------------D-I--VV--------------A--------------------VLD---------------------------T--------------GCDM-N------H-------------I---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGRN--------------------------------------------------------FTKD------------------------------YEGD------PNIYL----------------DNNGHG-------TH-V-----------------------AGTIA----ATENG-------------------------V-----GV------------------------------------LGV--APL-A--KMLVL---KV---L---------AG-DG-SG--S------------YEQ-------------------------------------I--------IEA--------------I-----------HY--------------------------------------AVNWRGPNKERV----RV-----------------------------------------ISMSLGGPQDVPEL-HEAIQNA-------------VKQ--------------------------------------------------------------DV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------NGDCNDNTEELDF---------------------------------------------------------------------------------------------------------------------------------------------------PGAYSE-----------------------------V---IE---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL---------------------------ERKIACF-----S--NSNQEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------DE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TYP---------E-GKY--AVLSG------TSMATPHVA----G---------------------------A------------------LALL----IKQCE--REYGRKLSEPEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------VPL-G-------YERTSEGNGLIDLLKE---------- 136
 137 ------------------------------IPSGVKLIHAPSVW--------EKS-EKGK--------------------------D-I--VI--------------A--------------------VLD---------------------------T--------------GCNT-E------H-------------I---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGYN--------------------------------------------------------FTTD------------------------------YESD------PNNFL----------------DNHGHG-------TH-V-----------------------AGIIA----ASENN-------------------------T-----GV------------------------------------IGV--APL-A--KLLIL---KV---F---------DG-KG-KS--S------------NEW-------------------------------------I--------TDG--------------I-----------MN--------------------------------------AINWRGPKGEKV----RI-----------------------------------------ISMSLSGKKDAYCL-HEAIKLA-------------VNN--------------------------------------------------------------NI-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------DGDCREETNELRY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYQE-----------------------------V---VE---VG--S------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DI---------------------------NKKIACK-----S--NSNNHL--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------KE--------------------------------I------------------------------------------------------------------WS-----------------------------------------------------------------------------------------------------------------------------TDK---------D-GGY--AKLSG------TSMATPHVS----G---------------------------A------------------AALI----IKQSE--KEFKRILSESEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TNI-G-------YSSFLVGNGMIDL------------- 137
 138 ---------------------------VAEIPSGVKLIHAPSVW--------EKS-EKGK--------------------------G-I--VI--------------A--------------------VLD---------------------------T--------------GCNT-E------H-------------I---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------IGGYN--------------------------------------------------------FTTD------------------------------YESD------PNNFL----------------DNHGHG-------TH-V-----------------------AGIIA----ASENN-------------------------T-----GV------------------------------------IGV--APL-A--KLLIL---KV---F---------DG-KG-KS--S------------NEW-------------------------------------I--------TDG--------------I-----------IN--------------------------------------AINWRGPNGEKV----RI-----------------------------------------ISMSLSGKKDAYCL-HEAIKLA-------------VNN--------------------------------------------------------------NI-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------DGDCREETNELRY---------------------------------------------------------------------------------------------------------------------------------------------------PGAYQE-----------------------------V---VE---VG--S------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DM---------------------------NKKIACD-----S--NSNNHL--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EE--------------------------------I------------------------------------------------------------------WS-----------------------------------------------------------------------------------------------------------------------------TDK---------D-GGY--AKLSG------TSMATPHVS----G---------------------------A------------------AALI----IKQSE--KEFQRTLSESEIY--------------------------------------------------------------------------------------------------------AQLI-------KRT------------------------------------------------------------------------------------------------TNI-G-------YSPLLVGNGILDLSRE---------- 138
 139 -----------------------------ELPEGIKVIKAPELW--------EKG-FKGK--------------------------N-V--TV--------------A--------------------VLD---------------------------T--------------GCDT-E------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------NQI---------IGGKN--------------------------------------------------------FTDD------------------------------DGGK------EDAIS----------------DYNGHG-------TH-V-----------------------AGTIA----ANDSN-------------------------G-----GI------------------------------------AGV--APE-A--SLLIV---KV---L---------GGENG-SG--Q------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVE------QKA----DI-----------------------------------------ISMSLGGPSDVPEL-QEAVSNA-------------VKN--------------------------------------------------------------GV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------EGDGDERTEELSY---------------------------------------------------------------------------------------------------------------------------------------------------PAAYNE-----------------------------V---IA---VG--S------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SV---------------------------ARESSEF-----S--NANKEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TLP---------N-KKY--GKLTG------TSMAAPHVS----G---------------------------A------------------LALI----KGFEE--DAFQRTLSESE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 139
 140 ---------------------------VNELPEGIKVIKAPEMW--------AKG-VKGK--------------------------N-I--KV--------------A--------------------VLD---------------------------T--------------GCDT-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------NQI---------IGGKN--------------------------------------------------------FTDD------------------------------DGGK------EDAIS----------------DYNGHG-------TH-V-----------------------AGTIA----ANDSN-------------------------G-----GI------------------------------------AGV--APE-A--SLLIV---KV---L---------GGENG-SG--Q------------YEW-------------------------------------I--------ING--------------I-----------NY--------------------------------------AVE------QKV----DI-----------------------------------------ISMSLGGPSDVPEL-KEAVKNA-------------VKN--------------------------------------------------------------GV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------EGDGDERTEELSY---------------------------------------------------------------------------------------------------------------------------------------------------PAAYNE-----------------------------V---IA---VG--S------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SV---------------------------ARELSEF-----S--NANKEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TLP---------N-KKY--GKLTG------TSMAAPHVS----G---------------------------A------------------LALI----KSYEE--ESFQRKLSESEVF--------------------------------------------------------------------------------------------------------AQLI-------RRT------------------------------------------------------------------------------------------------LPL-D-------IAKTLAGNGFLYLTAPDE-------- 140
 141 ---------------------------VNELPEGIKVIKAPELW--------AKG-FKGK--------------------------D-I--KI--------------A--------------------VLD---------------------------T--------------GCDI-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DRI---------VGGKN--------------------------------------------------------FTDD------------------------------DGGK------EDAIS----------------DYNGHG-------TH-A-----------------------SGTIA----ANDSN-------------------------G-----GI------------------------------------SGV--APE-A--SLLIV---KV---L---------GGKNG-SG--K------------YEW-------------------------------------I--------ING--------------I-----------DY--------------------------------------AVE------QKA----DI-----------------------------------------ISMSLGGPSDVPEL-KEAVANA-------------VKS--------------------------------------------------------------GV-----L--------------------------------------------------------------------------------------V---------------VCAAG-N--------EGDGDERTEELSY---------------------------------------------------------------------------------------------------------------------------------------------------PAAYNE-----------------------------V---IA---VG--S------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SI---------------------------ARKSSEF-----S--NANKEI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TLP---------N-HKY--GKLTG------TSMAAPHVS----G---------------------------A------------------LALI----KGLEQ--DAFQRTLSEAEVY--------------------------------------------------------------------------------------------------------AQLV-------RRT------------------------------------------------------------------------------------------------LPL-D-------IAKTLAGNGFLYLDAPEV-------- 141
 142 -------------------------------------IGAPEFW--------EES-DKGR--------------------------G-I--VI--------------A--------------------VLD---------------------------S--------------GCDI-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------ERI---------IGGAD--------------------------------------------------------FTSD------------------------------SHQDLTDIKNLKNVT----------------DILGHG-------TH-V-----------------------AGTIA----ATING-------------------------S-----GV------------------------------------VGV--APE-A--KLLIC---KV---LKRVE-DVGPGDSKF-RA--D------------YPN-------------------------------------I--------VKA--------------I-----------NE--------------------------------------CVKWRGPNQERV----RI-----------------------------------------ISMSLSGKEEDLEL-HNSIKKA-------------VLN--------------------------------------------------------------DI-----L--------------------------------------------------------------------------------------V---------------ICAAG-N--------KGDGNEHTKEVGY---------------------------------------------------------------------------------------------------------------------------------------------------PAYYPE-----------------------------V---VC---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NM---------------------------YKKLSQF-----T--NTHDEV--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EE--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------TFT---------NDKGY--ATLRG------TSMATPHVA----G---------------------------A------------------AALL----LKHHE--KKFHKKLTEP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 142
 143 -----------------------------EVPPNVNLIHAPEIW--------EQG-QHGE--------------------------G-I--II--------------A--------------------VLD---------------------------S--------------GCDV-N------H-------------P---------Q--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q--------------------------------------------------------------------------------------------------------------------------EQI---------IGGKN--------------------------------------------------------FTDT------------------------------GNSD--------EYI----------------DDHGHG-------TH-V-----------------------SGIIA----AKLDK-------------------------K-----EI------------------------------------VGV--APK-A--KLLIL---KV---LKKDP-K---NPDET-IG--N------------TDW-------------------------------------G--------VAA--------------I-----------DY--------------------------------------AISWRGPNQEKV----RI-----------------------------------------INMSIQGREGDDAY-HEAMKKA-------------VKN--------------------------------------------------------------DI-----L--------------------------------------------------------------------------------------V---------------VACAG-NFGDI--ERGGDCSPEHDEYSY---------------------------------------------------------------------------------------------------------------------------------------------------PAIYPE-----------------------------V---IS---VG--A------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AL---------------------------DKTFPCL-----T--NTNSQI--------------------------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------KE--------------------------------I------------------------------------------------------------------YS-----------------------------------------------------------------------------------------------------------------------------TMP---------N-NGY--GIGTG------TSMAAPHVS----G---------------------------A------------------LALL----INKCE--KDFDRSLTENELY--------------------------------------------------------------------------------------------------------AQLI-------KCT------------------------------------------------------------------------------------------------RSL-G-------KSKKLEGNGLIDLI------------ 143
 144 -------------------------------PYGLDLIKAREVW--------GAS-NKGE--------------------------G-I--VV--------------A--------------------VMD---------------------------S--------------GCDI-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q--------------------------------------------------------------------------------------------------------------------------GSI---------IDGYN--------------------------------------------------------FTDD------------------------------DNGD------SNIYK----------------DHRGHG-------TH-V-----------------------AGIIA----ARENE-------------------------F-----GI------------------------------------VGV--APK-S--KLLIL---KT---I----------NKNG-KG--K------------YQN-------------------------------------I--------INA--------------I-----------RY--------------------------------------AIDWRGPNNEKV----SV-----------------------------------------INMSLGGTQHDDEL-YKAIKDA-------------RKQ--------------------------------------------------------------GI-----L--------------------------------------------------------------------------------------L---------------VVAAG-N--------EGDGKSESIEISY---------------------------------------------------------------------------------------------------------------------------------------------------PGFYQE-----------------------------V---IQ---VG--S------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NQ---------------------------SEKISYF-----S--NSNINL--------------------------------------------------------------------------------D-----F------V-----------------A-----P-------------G-----------------GA--------------------------------V------------------------------------------------------------------IS-----------------------------------------------------------------------------------------------------------------------------TFL---------N-GQY--AKLSG------TSMATPYVS----G---------------------------A------------------LALI----IKLIPN-HNFNPTITSFLAY--------------------------------------------------------------------------------------------------------SYLL-------EHA------------------------------------------------------------------------------------------------KTL-G-------LSVFEEGNGLIQL------------- 144
 145 -------------------TVYELDAPLETIPTGITSIKAPELW--------EAS-KKGD--------------------------G-I--VI--------------A--------------------VID---------------------------S--------------GVDV-E------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------ENI---------IDGYN--------------------------------------------------------FTDD------------------------------DNSD------PHAYY----------------DYKGHG-------TH-V-----------------------AGIIA----ASENG-------------------------E-----GI------------------------------------IGV--APK-A--KLLIL---KV---L----------NKKG-LG--K------------IDA-------------------------------------L--------INA--------------I-----------EY--------------------------------------AINWRGKNNEQV----QV-----------------------------------------INLSLGSLKKSDDL-RRIIKKA-------------NKQ--------------------------------------------------------------GI-----I--------------------------------------------------------------------------------------L---------------VGASG-N--------YGDNDSETDEILF---------------------------------------------------------------------------------------------------------------------------------------------------PNFYKE-----------------------------V---IQ---IG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DL---------------------------EKKISKF-----S--NSNPNL--------------------------------------------------------------------------------D-----F------V-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------IS-----------------------------------------------------------------------------------------------------------------------------TYI---------G-QNY--SSMSG------TSMASPHVS----G---------------------------A------------------IALV----LNMLSN-KDLN--LTPATVY--------------------------------------------------------------------------------------------------------SYLL-------IHA------------------------------------------------------------------------------------------------IAL-G-------FSPNEEGNGYIQL------------- 145
 146 ----------------------------DLIDWGLKAIGVELAWQ-------K---TKGE--------------------------G-I--KV--------------A--------------------ILD---------------------------T--------------GIDE-D------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDNVKE---------------YIDF---TNSP-SQ-------------------------------------------------------------------------------------YE--D---M---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVA----A-MDN-------------------------------GI------------GMV----------------------GV--APK-A--ELYCA---KV---LGDN----------G-KG--G------------FEA-------------------------------------M--------IRG--------------I-----------KW---AI---------------------------------D----------RKV--DI-----------------------------------------ISMSLG-T----SS-RPP-------------------------E--------------------------VLYQ-----VIKQ---------ATAQ----GI-----V--------------------------------------------------------------------------------------F---------------VAATG-N------------------E-----NS---QVCY---------------------------------------------------------------------------------------------------------------------------------------P-AAYD-E---------------------------V---IA---VS--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------EN-------M----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QH-PQF-----S--N--------H-G-----------------IEN------------------------------------------------------E-----I------C-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-TYK----------------------------------------------------------------------------------------------------EG-------------------HY-AR----------------LSG------TSMATPIIS----G---------------------------A------------------IA-L----IL----A-------RYKQLHNGAKP-----------------------------------------------------------------------------S---------------------VSAV-------HEL-------------------------LQHMV------------------------------------------------------------------------KDLGIQGRDEIYGAGIINLA------------ 146
 147 --------------------------------------------------------------------------------------------V--------------A--------------------ILD---------------------------T--------------GIDE-D------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDNVKK---------------YIDF---TNSP-SQ-------------------------------------------------------------------------------------YK--D---M---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVA----A-MDN-------------------------------GI------------GMV----------------------GV--APK-S--ELYCA---KV---LGDN----------G-KG--G------------FEA-------------------------------------M--------VRG--------------I-----------KW---AM---------------------------------D----------CKV--DV-----------------------------------------ISMSLG-T----AS-RPP-------------------------E--------------------------VLYQ-----TIKQ---------AISQ----GI-----V--------------------------------------------------------------------------------------F---------------VAATG-N------------------E-----NS---QVCY---------------------------------------------------------------------------------------------------------------------------------------P-AAYD-E---------------------------V---IA---VS--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------EK-------M----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QH-SQF-----S--N--------Q-G-----------------IEN------------------------------------------------------E-----I------C-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-TYK----------------------------------------------------------------------------------------------------EG-------------------YY-AR----------------LSG------TSMATP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 147
 148 --------------------------------------------------------------------------------------------V--------------A--------------------ILD---------------------------T--------------GIDA-T------H-------------P---------D--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANYKK---------------GMNF--TTNNF-TD-------------------------------------------------------------------------------------IM--D---R---------------------K--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIIA----G-CDN-------------------------------SI------------GIV----------------------GV--APK-A--ELYIA---KV---LADD----------G-SG--L------------VEA-------------------------------------I--------VKG--------------I-----------DW---AI---------------------------------S----------EQV--DI-----------------------------------------ISMSLG-S----SN-DPG-------------------------P--------------------------VLHD-----AIKR---------AHEA----GI-----I--------------------------------------------------------------------------------------I---------------VAATG-N------------------E-----NT---HVGW---------------------------------------------------------------------------------------------------------------------------------------P-ASYD-E---------------------------V---IA---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------RN-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DR-ATF-----S--N--------F-G-----------------SET------------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------YS-TYP----------------------------------------------------------------------------------------------------VN-------------------RY-AK----------------LSG------TSMATP---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 148
 149 RYIEEDGVAYAFGFSNYTDVQWNVK-----MINAPRLGRLFSHIW--------RR-AFGY--------------------------G-V--KV--------------A--------------------VLD---------------------------T--------------GIDY-K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HPELSGKVVYCINTLGNTLYKGT-------NLRKCADRK--------------------------------------------------------------------------------------------------------------------------------------------------CHG-------TH-V-----------------------AGIIA----ASLNN---------------------------------------------------------------VSA---AGV--VPK-V--QLIAV---KV---LYDS----------G-SG--Y------------YSD-------------------------------------I--------AEG--------------I-----------IE--------------------------------------A----------VKAGALI-----------------------------------------LSMSLGGPTDASVL-RDASYWA-----------------------------------------------------------------------YQQ----GA-----V--------------------------------------------------------------------------------------Q---------------IAAAG-NS--------GDGDPLTNNVGY---------------------------------------------------------------------------------------------------------------------------------------------------PAKY--SC---------------------------V---IA---AA--A------------------------------VDQNGSV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTW-----S--S--------D-G-P-EV---------------------------------------------------------------------D-----T------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-TYP-----------------------------------------------------------------------------------------------------------------------GGRY-AY----------------MSG------TSMATPHVT----G---------------------------V------------------AALIQALRLASGKRLLT----------------------------------------------------------------------------PDE--------------V---------------------YQVI-------TST-----------------------------------------------------------------------AKDIG-----------PPGFD-------------------VFSGYGLVDAYAAVV-------- 149
 150 ----------------------------AQTIPWGIERVKAPSVW-------SIT-DGSV--------------------------SVI--QV--------------A--------------------VLD---------------------------T--------------GVDY-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANI-----------------------------------------------------------------------------------AWCVS---TLRGKVSTKLRDCADQN--------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------IGTIA----AL-NN-------------------------------DI------------GVV----------------------GV--APG-V--QIYSV---RV---LDAR----------G-SG--S------------YSD-------------------------------------I--------AIG--------------I-----------EQ---AILGPDGVADKDGDGIIAGDPDD-----D------A----------A----EV-----------------------------------------ISMSLG---------------G--------------------PA----------------------------DDSYLYDMIIQ---------AYNA----GI-----V--------------------------------------------------------------------------------------I---------------VAASG-NE--------GA---------P--------SPSY---------------------------------------------------------------------------------------------------------------------------------------P-AAYP-E---------------------------V---IA---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------SN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NI-ASF-----S--N--------R-QPE-V-----------------------------------------------------------------------------------S-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-TYP---------------------------------------------------------------------------------------------------------------------D--DSY-ET----------------LMG------TSMATPHVS----G---------------------------V------------------VALIQAAYYQKYGKILPVGTFDDISKNT----------------------------------------------------------------------------------V---------------------RGIL-------HIT-----------------------------------------------------------------------------------------------------ADDLGPTGWDADYGYGVVRAALAVQ-------- 150
 151 -----------------------------KINDGIDFINAKKYW--------ENG-HYGQ--------------------------D-T--II--------------A--------------------VID---------------------------T--------------GCDI-N------H-------------E---------E--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--------------------------------------------------------------------------------------------------------------------------DNI---------IGTFN--------------------------------------------------------FTDD------------------------------DNGK------ISIAT----------------DYTGHG-------TH-V-----------------------SGIIA----AT-NK-------------------------K-----HS------------------------------------IGI--APK-A--KLLVI---KA---I----------GHTS-IS--T------------HKH-------------------------------------L--------IKA--------------I-----------RF--------------------------------------ATAWRGKNGERV----DI-----------------------------------------MNLSLGTKSDVPEL-RKAVDEA-------------LQE--------------------------------------------------------------NI-----F--------------------------------------------------------------------------------------V---------------VVAAG-N--------YGDGSELTDEILY---------------------------------------------------------------------------------------------------------------------------------------------------PGYYEE-----------------------------V---IQ---VG--A------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GK---------------------------NLVPTHM-----S--NTNQNI--------------------------------------------------------------------------------D-----F------L-----------------S-----L-------------G-----------------ES--------------------------------V------------------------------------------------------------------YS-----------------------------------------------------------------------------------------------------------------------------TYP---------Q-NNY--IRLTG------TSVATPHIT----G---------------------------A------------------ISLI----LSYF---KAKHLPFSQNIIY--------------------------------------------------------------------------------------------------------QYLL-------SHS------------------------------------------------------------------------------------------------FLLKG-------YTNKTQGNGVLKL------------- 151
 152 DLGGNNW-------GADLVKAPEVWA---------------------------QG-YTGK--------------------------G-V--VV--------------A--------------------VVD---------------------------T--------------GVDY-N------H-------------E---------D--------------------------------L---------------------K----------------N-----------------------------------------------------NIW---------------------------------------------------------------------------------------------------------------------------TNTKEIAGNGIDDDGNGYIDDNYGWNFADKNNN------------TL-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTIA----GEN-N-------------------------------N-------------YGVT---------------------GI--AYD-A--KIMPV---KV---LNES----------G-SG--S------------YSS-------------------------------------I--------AKG--------------I-----------RY---AV--------------------D-----N------G----------A----NV-----------------------------------------INLSLG---------GTS---S--------------------NR--------------------------TLES-----AINY-A--------SSK----GV-----I--------------------------------------------------------------------------------------V---------------VMAAG-ND--------GE--------------S---SPDY---------------------------------------------------------------------------------------------------------------------------------------P-ARYA-S----KA---------------------G---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------NN-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-ADF-----S--NRSGTNQISY----------------------------------------------------------------------------------V------T-----------------A-----P-------------G-----------------VK--------------------------------V------------------------------------------------------------------YS-SVP---------------------------------------------------------------------------------------------------------------NN--------QY-AT----------------YSG------TSMATPHVA----G---------------------------V------------------VA-L----ML----S-------ANPSLT-----------------------------------------------------------------DAQ--------------V---------------------RQIV-------AET-------------------------SE------------------------------------------------------------------------N-STQSTNSSLNISNVSS----------------- 152
 153 -LGGDNW-------AADAIKAPEVWA---------------------------KG-YTGQ--------------------------G-T--IV--------------A--------------------VID---------------------------S--------------GVDY-N------H-------------S---------D--------------------------------L---------------------S----------------A-----------------------------------------------------NIW---------------------------------------------------------------------------------------------------------------------------KNTKEIAGNGKDDDSNGYIDDVNGWNFVGNNNN------------PL-----------------------------------------------------------------------------------------D---D---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AVK-N-------------------------------N-------------FGVT---------------------GI--AYN-A--KIMPV---KV---LNSG----------G-QG--T------------SSA-------------------------------------I--------ANG--------------I-----------RY---AV--------------------D-----N------G----------A----NV-----------------------------------------INLSLG---------SSS---P--------------------NS--------------------------DEKS-----AIQY-A--------ASK----GA-----I--------------------------------------------------------------------------------------V---------------VSAAG-NE--------GE--------------NGAVSPYY---------------------------------------------------------------------------------------------------------------------------------------P-AQYA-T----DW---------------------G---LA---VG--A------------------------------V-----------------------------Y------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-------------------------------------------------------------------------------------NH-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-TSF-----S--NPPGKTPLAY----------------------------------------------------------------------------------V------T-----------------A-----P-------------GAYFEGDLDLVAEDGHQLIG--------------------------------I------------------------------------------------------------------HS-TLP---------------------------------------------------------------------------------------------------------------GN--------KY-GF----------------EDG------TSMAAPHVA----G---------------------------V------------------IA-L----ML----S-------AKKGLT-----------------------------------------------------------------DAQ--------------V---------------------RQIV-------TTT-------------------------AA------------------------------------------------------------------------N-SLA------------------------------ 153
 154 ---------------------------------------------------LEHLKQMNIQSMWDKGYQGEGIT------------------I--------------A--------------------ILD---------------------------S--------------GCDI-N------HPYLK--DKIVHK-----YNLTKDD---------------------DTDRDNV-TDYI-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------ASLIV----SDNYN------------------------------------------------------------------GVITGV--SPK-A--NLLIY---KV---IDKDGLGDYNVVAQG----------------------------------------------------------V--------YAA-----------------------------------------------------------------------------AQRGADI-----------------------------------------INVSLGG------------------------------------------------------------------------SEPAPQIHEAIKSALRM----GC-----L--------------------------------------------------------------------------------------V---------------VCASG-NEG-------------DGNEETVELLY----------------------------------------------------------------------------------------------------------------------------------------------PGCYQE-----------------------------C---VQ---VG--A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-DNDYAITNF-----SN-T-------------------------------------------------------------------------------------NQFIDCV------------------------ANGNA--LL-----------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVKDNKIMAL---------SG------TSQSVPLVC----G---------------------------A------------------LALLKEYGRKELGKELNAYELYD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLLKNTKSIPN---ASENQQGHGYV--------------- 154
 155 --------------------PAVQDPKLPDMFMSVYKIHAYDTWI-------NYG-VLGD--------------------------N-V--TV--------------A--------------------VLD---------------------------T--------------GIDV-G------H-------------P---------F--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QVTL-------------------------------------DGRPKIVD-------------------------IYDASDEGIAQIYYATNVTENGTITVNMTVPVYWGFY------AMYYGHEQITDYTMGTYYVGGINGSEYYLGLLPERYFDLNNLTSRPDDLMGDLNDVYPVLIVNQSGNFVAYIDFNLNNDFTDDQPIGLFTETGDYFQTPDTLVDIALAKVHIGDMSN------PDNYLYTVPTEDGIGYAMFMWDAQGHG-------TH-V-----------------------SGTLA----GVGLP-------------------------TDPVFNGT------------------------------------YGV--APN-A--QLMEV---KV---L---------PGEFG-FG--A------------TSW-------------------------------------I--------ING--------------M-----------IY--------------------------------------AAS------NGA----DV-----------------------------------------ISMSLGGGGEINDG-IESPENF-------------YVNLLTDWF--------------------------------------------------------GV-----T--------------------------------------------------------------------------------------F---------------AIAAG-N--------EG---PTTNTVHA---------------------------------------------------------------------------------------------------------------------------------------------------PGDSDL-----------------------------V---IT---VG--A------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSSLRWQIFYGVDGV---------------------------ADTVASF-----S--SRGPRMDGLLDP--------------------------------------------------------------------------D-----V------I-----------------A-----P-------------G-----------------EM--------------------------------I------------------------------------------------------------------FS-----------------------------------------------------------------------------------------------------------------------------SLPLWYTVTNNDSYNYY--GIWDG------TSMATPHVS----G---------------------------A------------------VALM----ISYA---KQHNLTYDPIMIK--------------------------------------------------------------------------------------------------------RALE-------LSA------------------------------------------------------------------------------------------------KPV-N-------GTLIDQGFGLIQVDKAIE-------- 155
 156 --------------------KTKEPSLEPKMYNSTWVINALQFIQ-------EFG-YDGS--------------------------G-V--VV--------------A--------------------VLD---------------------------T--------------GVDP-N------H-------------P---------F--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SITP-------------------------------------DGRRKIIE-------------------------WKDFTDEGFVDTSFSFSKVVNGTLIINTTFQVASGLTLNESTGLMEYVVKTVYVSNVTIGNITSAN-------GIYHFGLLPERYFDLNFDGDQEDFYPVLLVNSTGNGYDIAYVDTDLDYDFTDEVPLGQYNVTYDVAVFSYYYGPLNYVLAEIDPNGE---------------------YAVFGWDGHGHG-------TH-V-----------------------AGTVA----GYDSNNDAWDWLSMYSGEWEVFSRLYGWDYTNVTTDTV------------------------------------QGV--APG-A--QIMAI---RV---L----------RSDG-RG--S------------MWD-------------------------------------I--------IEG--------------M-----------TY--------------------------------------AAT------HGA----DV-----------------------------------------ISMSLGGNAPYLDG-TDPESVA-------------VDE-LTEKY--------------------------------------------------------GV-----V--------------------------------------------------------------------------------------F---------------VIAAG-N--------EGPG---INIVGS---------------------------------------------------------------------------------------------------------------------------------------------------PGVATK-----------------------------A---IT---VG--A------------------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVPINVGVYVSQALGYPDYYGFYYFPAYTNVRIAFF-----S--SRGPRIDGEIKP--------------------------------------------------------------------------N-----V------V-----------------A-----P-------------G-----------------YG--------------------------------I------------------------------------------------------------------YS-----------------------------------------------------------------------------------------------------------------------------SLPMWI--------GGA--DFMSG------TSMATPHVS----G---------------------------V------------------VALL----ISGA---KAEGIYYNPDIIK--------------------------------------------------------------------------------------------------------KVLE-------SGA------------------------------------------------------------------------------------------------TWLEGDPYTGQKYTELDQGHGLVNVTKSWE-------- 156
 157 --------------VWLDGVRKASLDTSVGQIGTPKAW--------------EAG-YDGK--------------------------G-V--KI--------------A--------------------VLD---------------------------T--------------GVDA-T------H-------------P---------D--------------------------------L---------------------K----------------GQVTA---------------------------SKN----------------------------------------------------------------------------------------------------------------------------------------------------------------FTS--------------A------------PT-----------------------------------------------------------------------------------------T---G---------------------D-------V----------------------------------------------------------------------V-------------------------------------------------------------------GHG-------TH-V-----------------------ASIAA----GTG---------------------------------AQ------------SKGTYK-------------------GV--APG-A--KILNG---KV---LDDA----------G-FG--D------------DSG-------------------------------------I--------LAG--------------M-----------EW---AA--------------------A-----Q------G----------A----DI-----------------------------------------VNMSLGG------M-DTP---E--------------------TD--------------------------PLEA-----AVDKLS--------AEK----GI-----L--------------------------------------------------------------------------------------F---------------AIAAG-NE--------GP----------QSIGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--S-A----DS---------------------A---LT---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------KD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------T-G---P--------------------RL------GDGAV---K--------------------P------------D-----L------T-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TA-ASA-----------------------------------------------------------------------------------------------KGNDIAKEVG----EKPA--------GY-MT----------------ISG------TSMATPHVA----G---------------------------A------------------AA-L----LK----Q-------QHPEWK-----------------------------------------------------------------YAE--------------L---------------------KGAL-------TAS-------------------------------------------------------------------------------------------------------TKDGKYTPFEQGSGRVQVDKAIT-------- 157
 158 -------------------KTYSLEREITSKVIKADLVSSKKDQL-------GNY-ITGN--------------------------N-I--KI--------------G--------------------IID---------------------------T--------------GVDY-T------H--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KELG-------------------------------------GGKFPNLK---------------------------VVGGYDFADNDPDPMDYD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAA----GSEK-----------------------------------------------------------------------GI--AKN-A--KIYAY---KV---FSKN------------STTTT------------SSL-------------------------------------I--------IKA--------------L-----------DQ--------------------------------------A----------VKDKCNV-----------------------------------------VNISIGIQNGGATS-DDPESDA-------------VRR-----------------------------------------AV-------------GS----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NN--------GVPGEFFDY------------------------------------------------------------------------------------------------------------------------------------------------------P-ISSPGS---------------------------VDLAIG---VG--A------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDGITGVINCSGKSILAQYPNESPDFKEGTYQMVYCGLGRKEDFQGVDVKGKIALIERGQIYFGDKDLNAKDAGAIGVIVYNNVSGMPKITLVSQNNPSRNDFIPFLFVSFTDGKFLKDHTNENINITNEYGLGLI-------------------------------------------------------------------------------------------------------------AEF-----S--S--------S-GPT-NDFYLKP----------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VN--------------------------------L------------------------------------------------------------------TS-TYLNNSYME----------------------------------------------------------------------------------------------------------------------------------------MSG------TSMASPVVA----G---------------------------S------------------VAL------------------------------------------------------------------------------------------------------------------------------------V-------KQA-------------------------------------------------------------------------------------------------------------------------------------- 158
 159 TYTDYAW----------------------------------------------DV-TKGS--------------------------SGQ--EI--------------A--------------------VID---------------------------T--------------GVDY-T------H-------------P---------D--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGKVIKG---YDFVDNDYDP-MD--------------------------------------------------------------------------------------------------------------L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TH-V-----------------------AGIAA----AETNN-------------------------------AT------------GIA----------------------GM--APN-T--RILAV---RA---LDRN----------G-SG--T------------LSD-------------------------------------I--------ADA--------------I-----------IY---AA--------------------D-----S------G----------A----EV-----------------------------------------INLSLG---------CDC---H--------------------TT--------------------------TLEN-----AVNY-A--------WNK----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NN--------GS---------S--------TTFE---------------------------------------------------------------------------------------------------------------------------------------P-A--S-Y----EN---------------------V---IA---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------YD-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ASF-----S--N--------Y-G---T--------------------WV------------------------------------------------D-----V------V-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VS-T----------------------------------------------------------------------------------------------------------ITGN-------------RY-AY----------------MSG------TSMASPHVA----G---------------------------L------------------AALL----ASQ-----------GRNNIE-----------------------------------------------------------------IRQA--------------------------------------I-------EQT------------------------ADK------------------------------------------------------------------------ISG-------TGTYFKYGRINSYNAVT-------- 159
 160 MQIPKAW----------------------------------------------DI-TRGS--------------------------TDT--VV--------------A--------------------VVD---------------------------S--------------GVQS-T------H-------------P---------D--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGKVISG---YDYVQNNTDPSKD--------------------------------------------------------------------------------------------------------------E---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------AGTIA----AVTDN-------------------------------EI------------GIA----------------------GI--APN-V--KILSV---RV---LDRN----------G-YS--Y------------NDV-------------------------------------I--------ANG--------------I-----------TY---AA--------------------D-----H------G----------A----KV-----------------------------------------INLSIA---------MQD---P--------------------SQ--------------------------VLED-----AVNY-A--------WDK----GV-----V--------------------------------------------------------------------------------------L---------------VAGAG-NA--------ST---------S--------QPYY---------------------------------------------------------------------------------------------------------------------------------------P-A--A-Y----SN---------------------V---IS---VA--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------ND-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-WDR-----S--N--------Y-G---I--------------------SV------------------------------------------------D-----V------S-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------MS-T----------------------------------------------------------------------------------------------------------VPTNWNLET--------PY-ST----------------KSG------TSMATANVS----G---------------------------V------------------VALL----ASQ-----------GFSNIQ-----------------------------------------------------------------IRDA--------------------------------------I-------EKS------------------------ADK------------------------------------------------------------------------IPG-------TGEYWKHGRVNAYKA---------- 160
 161 ----Q-Y-------GLLKIQA---------------PQA-----W-------DAQ-RSAP--------------------------A-V--KI--------------A--------------------IVD---------------------------T--------------GVQG-N------H-------------P---------D--------------------------------L--------------------------------------S----------------------S------------------------------KVI----------------------------------------------------------------------------------------------------------------------------------YG------HDY-V-----DNDS---Q------------SD-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAG----ALT-N-------------------------------NN------------IGI--A-------------------GV--APQ-S--SIYAV---RV---LDSQ----------G-SG--T------------LDA-------------------------------------V--------AKG--------------I-----------RE---SA----------DAG-------------------------------A----KV-----------------------------------------ISLSLG-------A-SSG---G---------------------T--------------------------ALQQ-----AIQY-A--------WNK----GA-----V--------------------------------------------------------------------------------------I---------------VAAAG-ND--------GN---------T--------RPNY---------------------------------------------------------------------------------------------------------------------------------------P-A--Y-Y----NE---------------------V---IA---VA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------ND-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SYF-----S--N--------Y-G---S--------------------WV------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------YS-TYK--------------------------------------------------------------------------------------------------------G-------S--------TY-RS----------------LSG------TSMATPQVA----G---------------------------V------------------AG-L----LA----N-------QG---Y-------------------------------------------------------------T---NVQ--------------I---------------------RQII-------EAT-------------------------SD------------------------------------------------------------------------K------------IS--GTGTYWKNGRVNANKAV- 161
 162 YFNNQ-Y-------GLQKIQA---------------PQA-----W-------DSQ-RSDP--------------------------G-V--KV--------------A--------------------IID---------------------------T--------------GVQG-S------H-------------P---------D--------------------------------L--------------------------------------A----------------------S------------------------------KVI----------------------------------------------------------------------------------------------------------------------------------YG------HDY-V-----DNDN---V------------SD-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGITG----ALT-N-------------------------------NS------------VGI--A-------------------GV--APQ-T--SIYAV---RV---LDNQ----------G-SG--T------------LDA-------------------------------------V--------AQG--------------I-----------RE---AA----------DSG-------------------------------A----KV-----------------------------------------ISLSLG-------A-PNG---G---------------------T--------------------------ALQQ-----AVQY-A--------WNK----GS-----V--------------------------------------------------------------------------------------I---------------VAAAG-NA--------GN---------T--------KANY---------------------------------------------------------------------------------------------------------------------------------------P-A--Y-Y----SE---------------------V---IA---VA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------SD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SSF-----S--T--------Y-G---S--------------------WV------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------SN--------------------------------I------------------------------------------------------------------YS-TYK--------------------------------------------------------------------------------------------------------G-------S--------TY-QS----------------LSG------TSMATPHVA----G---------------------------V------------------AA-L----LA----N-------QG---Y-------------------------------------------------------------S---NTQ--------------I---------------------RQII-------EST-------------------------SD------------------------------------------------------------------------K------------IS--GTGTYWKNGRVNAYKAVQ 162
 163 --QTQ-Y-------GLTKIQA---------------PQA-----W-------DTQ-RSDS--------------------------N-I--KI--------------A--------------------IVD---------------------------T--------------GVQG-T------H-------------P---------D--------------------------------L--------------------------------------S----------------------S------------------------------KVI----------------------------------------------------------------------------------------------------------------------------------HG------HDY-V-----SDDA---I------------SN-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAA----AIT-N-------------------------------NK------------KGI--A-------------------GV--APQ-A--SIYAV---RV---LDNQ----------G-SG--T------------LDA-------------------------------------V--------AQG--------------I-----------RE---AA----------DSG-------------------------------A----QV-----------------------------------------ISLSLG-------A-PDG---G---------------------T--------------------------ALQE-----AVQY-A--------WDK----GA-----V--------------------------------------------------------------------------------------I---------------VAAAG-ND--------GD---------S--------TPNY---------------------------------------------------------------------------------------------------------------------------------------P-A--Y-Y----DK---------------------V---IS---VA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------YD-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SYF-----S--T--------Y-G---K--------------------WV------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------SN--------------------------------I------------------------------------------------------------------YS-TYK--------------------------------------------------------------------------------------------------------G-------S--------TY-RT----------------LSG------TSMATPHVA----G---------------------------L------------------AA-L----LA----N-------KG---Y-------------------------------------------------------------S---NSQ--------------I---------------------RQII-------EDT-------------------------AD------------------------------------------------------------------------K------------LP--GTDNNWKYGRVNAYKAV- 163
 164 FSSRQ-Y-------GPQKIQA---------------PQA-----W-------DIA-EG-S--------------------------G-A--KI--------------A--------------------IVD---------------------------T--------------GVQS-N------H-------------P---------D--------------------------------L--------------------------------------A----------------------G------------------------------KVV----------------------------------------------------------------------------------------------------------------------------------GG------WDF-V-----DNDS---T------------PQ-----------------------------------------------------------------------------------------N---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAA----AVT-N-------------------------------NS------------TGI--A-------------------GT--APK-A--SILAV---RV---LDNS----------G-SG--T------------WTA-------------------------------------V--------ANG--------------I-----------TY---AA----------DQG-------------------------------A----KV-----------------------------------------ISLSLG-------G-TVG---N---------------------S--------------------------GLQQ-----AVNY-A--------WNK----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NA--------GN---------T--------APNY---------------------------------------------------------------------------------------------------------------------------------------P-A--Y-Y----SN---------------------A---IA---VA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------ND-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SSF-----S--T--------Y-G---S--------------------VV------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------SW--------------------------------I------------------------------------------------------------------YS-TYP--------------------------------------------------------------------------------------------------------T-------S--------TY-AS----------------LSG------TSMATPHVA----G---------------------------V------------------AG-L----LA----S-------QG---R-------------------------------------------------------------S---ASN--------------I---------------------RAAI-------ENT-------------------------AD------------------------------------------------------------------------K------------IS--GTGTYWAKGRVNAYKAVQ 164
 165 ------------------------------YIGANDAW-DLG--------------YTGK--------------------------G-I--KV--------------A--------------------IID---------------------------T--------------GVEY-N------H-------------P---------D--------------------------------L---------------------K----------------KNFGQ---------------------------YKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---Y---------------------D-------P----------------------------------------------------------------------KE------------------------------------------TPTGDPRGGAT-------------DHG-------TH-V-----------------------AGTVA----ANG--------------------------------------------------TIK-------------------GV--APD-A--TLLAY---RV---LGPG----------G-SG--T------------SEN-------------------------------------V--------IAG--------------V-----------ER---AV--------------------Q-----D------G----------A----DV-----------------------------------------MNLSLGNS-----L-NNP---D--------------------W---------------------------ATST-----ALDW-A--------MSE----GV-----V--------------------------------------------------------------------------------------A---------------VTSNG-NS--------GP--------NGWTVGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-S----RE---------------------A---IS---VG--A------------------------------T-----------------------------Q------------------------------------------------------------------------------------------------LPL----------NEYAV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TF-----G--S--------R-G---P--------------------VM------DTWMI---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS-TIP-----------------------------------------------------------------------------------------------TH--------D--PDHPY--------GY-GS----------------KQG------TSMASPHIA----G---------------------------A------------------VA-V----IK----Q-------AKPKWS-----------------------------------------------------------------VEQ--------------I---------------------KTAI-------MNT------------------------AVT------------------------------------------------------------------------LKD-SDGEVYPHNAQGAGSARIMNA---------- 165
 166 ------------------------------YIGANDAW-DLG--------------YTGK--------------------------G-M--KV--------------A--------------------VID---------------------------T--------------GVEY-N------H-------------P---------D--------------------------------L---------------------K----------------KNFGP---------------------------YKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---Y---------------------T-------P----------------------------------------------------------------------KE------------------------------------------TPVGDPRGEAT-------------DHG-------TH-V-----------------------AGTVA----ANG--------------------------------------------------TIK-------------------GV--APD-A--TLLAY---RV---LGPG----------G-SG--T------------TEN-------------------------------------V--------IAG--------------V-----------ER---AV--------------------Q-----D------G----------A----DV-----------------------------------------MNLSLGDT-----V-NSP---D--------------------W---------------------------ATST-----ALDW-A--------MSE----GV-----V--------------------------------------------------------------------------------------A---------------VTSNG-NS--------GP--------NGWTVGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-S----RE---------------------A---IS---VG--A------------------------------T-----------------------------Q------------------------------------------------------------------------------------------------LPL----------NEYAV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T---------------------------------------------VM------DTWMI---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS-TIP-----------------------------------------------------------------------------------------------TH--------D--SDNPY--------GY-GS----------------KQG------TSMASPHIA----G---------------------------A------------------VA-V----IK----Q-------AKPKWS-----------------------------------------------------------------VEQ--------------I---------------------KSAI-------MNT------------------------AVT------------------------------------------------------------------------LKD-GDGKVYPHNTQGAGSA--------------- 166
 167 NVTYKTDNMKDKDVTISEDAVSPQMDDSAPYIGANDAW-DLG--------------YTGK--------------------------G-I--KV--------------A--------------------IID---------------------------T--------------GVEY-N------H-------------P---------D--------------------------------L---------------------K----------------KNFGQ---------------------------YKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---Y---------------------D-------P----------------------------------------------------------------------KE------------------------------------------TPTGDPRGEAT-------------DHG-------TH-V-----------------------AGTVA----ANG--------------------------------------------------TIK-------------------GV--APD-A--TLLAY---RV---LGPG----------G-SG--T------------TEN-------------------------------------V--------IAG--------------V-----------ER---AV--------------------Q-----D------G----------A----DV-----------------------------------------MNLSLGNS-----L-NNP---D--------------------W---------------------------ATST-----ALDW-A--------MSE----GV-----V--------------------------------------------------------------------------------------A---------------VTSNG-NS--------GP--------NGWT---------------------------------------------------------------------------------------------------------------------------------------------------G--E-T----KT---------------------T---FK---LT--V------------------------------S-----------------------------K-------------------------------------------------------------------------------------------------AL----------GEQVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF-----S--S--------R-G---P--------------------VM------DTWMI---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS-TIP-----------------------------------------------------------------------------------------------TH--------D--PDHPY--------GY-GS----------------KQG------TSMASPHIA----G---------------------------A------------------VA-V----IK----Q-------AKPKWS-----------------------------------------------------------------VEQ--------------I---------------------KAAI-------MNT------------------------AVT------------------------------------------------------------------------L---------------------------------- 167
 168 ------------------------------YIGANDAW-KLG--------------YTGK--------------------------G-V--KV--------------A--------------------IID---------------------------T--------------GVEY-K------H-------------P---------D--------------------------------L---------------------K----------------KNFGQ---------------------------YKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---Y---------------------D-------P----------------------------------------------------------------------EE------------------------------------------TPAGDPRGAAT-------------DHG-------TH-V-----------------------AGTVA----ANG--------------------------------------------------TIK-------------------GV--APD-A--TLLAY---RV---LGPG----------G-SG--T------------TEN-------------------------------------V--------IAG--------------I-----------ER---AV--------------------Q-----D------G----------A----NV-----------------------------------------MNLSLGNS-----V-NNP---D--------------------W---------------------------ATST-----ALDW-A--------MSE----GV-----T--------------------------------------------------------------------------------------A---------------VTSNG-NS--------GP--------NNWTVGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-S----RE---------------------A---IS---VG--A------------------------------T-----------------------------Q------------------------------------------------------------------------------------------------LPL----------NEYAVSFGKAGGTKATFNLS-----------------------------------------------------------------------------------------------------VAKSL-------------------------------------------------------------------------------------TE-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-ADF-----S--S--------R-G---P--------------------VM------DTWMI---K--------------------P------------D-----V------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS-TIP-----------------------------------------------------------------------------------------------TH--------D--PANPY--------GY-GS----------------KQG------TSMASPHVA----G---------------------------A------------------AA-V----IK----Q-------AKPKWS-----------------------------------------------------------------PEQ--------------I---------------------KAAL-------MNT------------------------AET------------------------------------------------------------------------LTD-ADGDVYPHNAQGAGSIRIMKAI--------- 168
 169 ------------EELVSKEEYSPAMFDSAPFIGANDAW-DLG--------------FTGK--------------------------G-V--KV--------------A--------------------VID---------------------------T--------------GVDY-T------H-------------P---------D--------------------------------L---------------------A----------------PNFGE---------------------------YLG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------DN-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------QE------------------------------------------TPRGDPRGAET-------------THG-------SH-V-----------------------AGTIA----ANG--------------------------------------------------QIK-------------------GV--APD-A--TLLAY---RV---LGPG----------G-SG--S------------TEN-------------------------------------V--------VAA--------------I-----------ER---AV--------------------Q-----D------G----------A----DV-----------------------------------------MNLSLGNS-----L-NAP---D--------------------W---------------------------ATSI-----ALDQ-A--------MAE----GV-----V--------------------------------------------------------------------------------------A---------------VTSNG-NS--------GP--------NNWTVGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-S----K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AV----------GETMA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF-----S--S--------R-G---P--------------------VI------DTWMI---K--------------------P------------D-----V------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS-TVP-----------------------------------------------------------------------------------------------TF--------N--PDAPH--------GY-GA----------------KQG------TSMASPHVA----G---------------------------A------------------AA-V----IL----E-------ANPSWG-----------------------------------------------------------------VYE--------------V---------------------KSAL-------MNT------------------------A------------------------------------------------------------------------------------------------------------- 169
 170 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 170
 171 --------------------------------------------------------LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDA--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HDG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENAYPVMAQGSGLINIPKAA--------- 171
 172 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKA---------- 172
 173 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKA---------- 173
 174 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 174
 175 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 175
 176 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-SNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKA---------- 176
 177 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------VKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVT----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 177
 178 ------------------------------------------------------S-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------GG------------------------GY-ES----------------HNG------TSMAAPQVT----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 178
 179 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-I-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HDG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENAYPVMAQGSGLINIPKAA--------- 179
 180 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------TNY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDA--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------S----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------GG------------------------GY-ES----------------HNG------TSMAAPQVT----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 180
 181 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------VID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDA--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------T---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKA---------- 181
 182 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------VID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDA--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------T---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPSQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKA---------- 182
 183 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVAGS-----------------IKI-----------------------------------------------------------------------------------------------------GQPNK-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 183
 184 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQIA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNK-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 184
 185 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQIA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNK-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPIMAQGSGLINIPKAA--------- 185
 186 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GDF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 186
 187 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GDF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSAL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAA--------- 187
 188 ------------------------------------------------------S-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---D---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------GKI-----------------------------------------------------------------------------------------------------GQPVP-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 188
 189 ------------------------------------------------------S-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---D---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYSVMTQGSGLINIPKAV--------- 189
 190 ------------------------------------------------------P-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQIA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 190
 191 ------------------------------------------------------P-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTSQ-------------------------------------------------------------------------------------------------------------------------------PVP-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 191
 192 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------VID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNK-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNETTYPVMAQGSGLINIPKAA--------- 192
 193 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------VID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNK-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNETTYPVMAQGSGLINIPKAA--------- 193
 194 --------------------------------------------S-------GKP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---S---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------T---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVAGSSKTYQGLPLSKTKRKKNIKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KAAL-------ANN------------------------AKT------------------------------------------------------------------------LHD-VNENTYPVMAQGSGLINIPKAAQTNVLVKPN 194
 195 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AET------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 195
 196 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AET------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 196
 197 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AET------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 197
 198 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDE----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPKQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AET------------------------------------------------------------------------LKD-VNENTYPVMTQGSGLINIPKAV--------- 198
 199 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVT----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAV--------- 199
 200 -----------------------------------------------------KP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------Q----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GI--APN-A--SILAY---RV---MNDG----------G-TG--T------------TDD-------------------------------------I--------IQG--------------I-----------EH---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQD-----L-NVP---D--------------------Q---------------------------PVTM-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------KPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVA-------------------IKI-----------------------------------------------------------------------------------------------------GQPNQ-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-GNF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVT----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KSSL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPVMAQGSGLINIPKAV--------- 200
 201 --------------------NEEAPNIGGPTIGATEAW-NLKDPS-------GKP-LDGK--------------------------G-M--KV--------------A--------------------IID---------------------------S--------------GVDY-T------H-------------P---------D--------------------------------L---------------------K----------------ANY-----------------------------IGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDT--------------V------------DE-----------------------------------------------------------------------------------------D---N---------------------D-------P----------------------------------------------------------------------MD---------------------------------------------------GN-------------VHG-------TH-V-----------------------AGIIA----GNG--------------------------------------------------KIK-------------------GV--APN-A--SILAY---RV---MNDG----------G-TG--T------------TED-------------------------------------I--------IQG--------------I-----------ER---AI--------------------Q-----D------G----------A----DV-----------------------------------------LNLSLGQS-----L-NTP---D--------------------Q---------------------------PVTL-----TLER-A--------AKL----GV-----T--------------------------------------------------------------------------------------A---------------VVSNG-ND--------GP--------HPWSVDA----------------------------------------------------------------------------------------------------------------------------------------------P-G--N-A----SS---------------------V---IS---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------VSIPFPTFQVAGSSKTYQGLPLSKTKRKKNIKI-----------------------------------------------------------------------------------------------------GQPNP-------------------------------------------------------------------------------------TE-------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ANF-----S--S--------R-G---P--------------------SQ------GSWLI---K--------------------P------------D-----I------I-----------------A-----P-------------G-----------------VQ--------------------------------I------------------------------------------------------------------TS-TVP-----------------------------------------------------------------------------------------------RG------------------------GY-ES----------------HNG------TSMAAPQVA----G---------------------------A------------------VA-L----LR----Q-------MHPDWT-----------------------------------------------------------------TEQ--------------L---------------------KASL-------ANT------------------------AKT------------------------------------------------------------------------LKD-VNENTYPIMTQGSGLINIPKAAQTDVLVKPN 201
 202 -------------------------DVSNSVIGATNVWQQIKDAK-------GNP-VDGT--------------------------G-I--VI--------------A--------------------IID---------------------------T--------------GVDY-T------H-------------P---------D--------------------------------L---------------------G----------------GGFGP-----------------------NYKVIGG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------G------------DK-----------------------------------------------------------------------------------------D---P---------------------D-------P----------------------------------------------------------------------MD------------------------------------------SN----------------------GHG-------TH-V-----------------------AGIAA----ADG--------------------------------------------------KIK-------------------GV--APK-A--KILAY---KI---VAGG----------SRNA--S------------TEN-------------------------------------I--------IAG--------------I-----------ER---AV--------------------K-----D------G----------A----NV-----------------------------------------ANLSFGSASL--GT-SDP---E--------------------D---------------------------PENK-----AFDT-A--------ADA----GV-----L--------------------------------------------------------------------------------------S---------------SISAG-NQ--------GARC----QTKPYPLGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--G-A----RK---------------------V---LS---VA--A------------------------------S-----------------------------DDGIHPAINIVSPTVPEGQSIILGNYADLSPAFPKDQQFEVVVCGYGRPSDFEGVDVKGKIALVSRGPLGPNAIYFRDKDLNAKAAGAVGIIIYNNMPGIVSPTFNVQAGDEKKEYIPAIFVTQSDGLFIKDLINKGLKIKF-----------------------------------------------------------------------------------------NDVSN-------------------------------------------------------------------------------------LG-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ASF-----S--S--------M-G---P--------------------SS------DFY-F---K--------------------P------------E-----I------A-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------YS-TIP-----------------------------------------------------------------------------------------------GG------------------------AY-AS----------------WNG------TSMAAPHVA----G---------------------------A------------------IA-L----FK----Q-------VHPDFT-----------------------------------------------------------------SED--------------I---------------------KAAL-------MNT------------------------AVV------------------------------------------------------------------------LKNYQNNETITWLLQGSGRLNIASAISTPATIKPY 202
 203 ------------------------------------------------------H-FTGK--------------------------G-I--KV--------------A--------------------VID---------------------------T--------------GIDS-T------H-------------P---------D--------------------------------L---------------------K----------------KNY-----------------------------LKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---T---------------------N-------P----------------------------------------------------------------------ED---------------------------------------------------IV-------------GHG-------TH-V-----------------------AGIIA----ANG--------------------------------------------------RMK-------------------GV--APD-A--SILAY---RV---SDQG----------G-N----------------TEM-------------------------------------I--------IKA--------------I-----------NQ---AI--------------------E-----D------G----------A----HI-----------------------------------------INLSMGTS-----L-SGT---D--------------------A---------------------------PLNQ-----AIQK-A--------IAK----NI-----T--------------------------------------------------------------------------------------V---------------VTAAG-NS--------GP--------EQWSLSN----------------------------------------------------------------------------------------------------------------------------------------------L-T--S-T----PE---------------------A---IS---VG--N------------------------------A-----------------------------K------------------------------------------------------------------------------------------------QAREQKVVTIAQDSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ASN-----S--S--------R-G---P--------------------AV------GSWQI---K--------------------P------------D-----I------A-----------------A-----Y-------------G-----------------VD--------------------------------I------------------------------------------------------------------ES-TVP-----------------------------------------------------------------------------------------------RNMELNRSNIK--AFTKK--------GY-DI----------------MSG------TSMAAPRVA----G---------------------------A------------------AA-L----LK----Q-------AHPDWS-----------------------------------------------------------------PYE--------------I---------------------RAAL-------TST------------------------ATL------------------------------------------------------------------------IKE-PNNNIVTPLAQGSGLVDIEKAL--------- 203
 204 ------------------------------------------------------H-FTGK--------------------------G-I--KV--------------A--------------------VID---------------------------T--------------GIDS-T------H-------------P---------D--------------------------------L---------------------K----------------KNY-----------------------------LKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---T---------------------N-------P----------------------------------------------------------------------ED---------------------------------------------------IV-------------GHG-------TH-V-----------------------AGIIA----ANG--------------------------------------------------RMK-------------------GV--APD-A--SILAY---RV---SDQG----------G-N----------------TEM-------------------------------------I--------IKA--------------I-----------NQ---AI--------------------E-----D------G----------A----HI-----------------------------------------INLSMGTS-----L-SGT---D--------------------A---------------------------PLNQ-----AIQK-A--------IAK----NI-----T--------------------------------------------------------------------------------------V---------------VTAAG-NS--------GP--------EQWSLSN----------------------------------------------------------------------------------------------------------------------------------------------L-T--S-T----PE---------------------A---IS---VG--N------------------------------A-----------------------------K-------------------------------------------------------------------------------------------------AREQKVVTIAQDSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ASN-----S--S--------R-G---P--------------------AV------GSWQI---K--------------------P------------D-----I------A-----------------A-----Y-------------G-----------------VD--------------------------------I------------------------------------------------------------------ES-TVP-----------------------------------------------------------------------------------------------RNMELNRSNIK--AFTKK--------GY-DI----------------MSG------TSMAAPRVA----G---------------------------A------------------AA-L----LK----Q-------AHPDWS-----------------------------------------------------------------PYE--------------I---------------------RAAL-------TST------------------------ATL------------------------------------------------------------------------IKE-PNNNIVTPLAQGSGLVDIEKAL--------- 204
 205 ------------------------------------------------------H-FTGK--------------------------G-I--KV--------------A--------------------VID---------------------------T--------------GIDS-T------H-------------P---------D--------------------------------L---------------------K----------------KNY-----------------------------LKG----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------I------------DN-----------------------------------------------------------------------------------------D---T---------------------N-------P----------------------------------------------------------------------ED---------------------------------------------------TV-------------GHG-------TH-V-----------------------AGIIA----ANG--------------------------------------------------TMK-------------------GV--APD-A--SILAY---RV---SEDP----------G-D----------------TEM-------------------------------------I--------IKA--------------I-----------NQ---AI--------------------E-----D------G----------A----HI-----------------------------------------INLSLETP-----L-PGT---D--------------------T---------------------------PINQ-----AIQK-A--------IAK----NI-----T--------------------------------------------------------------------------------------V---------------VSGAG-NS--------GP--------EQWSLGS----------------------------------------------------------------------------------------------------------------------------------------------L-T--S-T----PE---------------------S---IS---VG--N------------------------------A-----------------------------K-----------------------------------------------------------------------------------------------------KVVTITQDSE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-DTD-----S--S--------R-G---P--------------------AI------GSWQI---K--------------------P------------D-----I------A-----------------A-----Y-------------G-----------------VD--------------------------------I------------------------------------------------------------------ES-TFP-----------------------------------------------------------------------------------------------RNMELNSSDIK--PFKKE--------GY-AI----------------MSG------TSMAAPRVA----G---------------------------A------------------AA-L----LK----Q-------AHPDWS-----------------------------------------------------------------PYE--------------I---------------------RAAL-------TST------------------------ATL------------------------------------------------------------------------IKE-PNNTIVTPLAQGSGLVDIAKAL--------- 205
 206 --------------------------------------------H-------AEN-ITGK--------------------------E-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------GAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PT-SP-GYVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APD-V--DLYAY---RV---LGPW----------G-GG--N------------TAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAMS-------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---INYGN--------AY-VR----------------LSG------TSMATPHVA----G---------------------------T------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQA---------- 206
 207 --------------------------------------------H-------AEN-ITGK--------------------------E-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------GAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PT-SP-GYVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APD-V--DLYAY---RV---LGPW----------G-GG--N------------TAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAMS-------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---INYGN--------AY-VR----------------LSG------TSMASPHVA----G---------------------------T------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-KNS----VYEVGAGRIDAYQA---------- 207
 208 --------------------------------------------H-------AEN-ITGK--------------------------E-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------GAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PT-SP-GYVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APD-V--DLYAY---RV---LGPW----------G-GG--N------------TAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------VSMS-------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TSP-----------------------------------------------------------------------------------------------EYINDPQ-DG---TNYSN--------AY-VR----------------LSG------TSMATPHVT----G---------------------------T------------------AA-L----IL----Q-------EHPKYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-KNS----VYEVGAGRIDAYQA---------- 208
 209 --------------------------IQPKMADSIPQI-GVDKLH-------AEN-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PE-YP-GLVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYSY---RV---LGPW----------G-GG--N------------TAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------VSMSIPTFSASVSNEKFENMQLLGKDFPDKLED-------------------------------------------------------------------------------------------EVSFKFETLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---INYGN--------AY-VR----------------LSG------TSMASPHVA----G---------------------------T------------------AA-L----IL----Q-------QNPKYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQAV--------- 209
 210 ----------------------------------------------------AEN-IMGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PE-YP-GLVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYAY---RV---LGPW----------G-GG--N------------SAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----AV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----AVNN-A--------MLS----GV-----A--------------------------------------------------------------------------------------T---------------VVAAG-NN--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AA---------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---INYGN--------AY-VR----------------LSG------TSMASPHVA----G---------------------------T------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQA---------- 210
 211 ----------------------------------------------------AEN-IMGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PE-YP-GLVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYAY---RV---LGPW----------G-GG--N------------SAG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----AVNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AA---------------------------------------------------------------------------------------------------------------------------------TLSNIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VN------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---INYGN--------AY-VR----------------LSG------TSMASPHVA----G---------------------------T------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQA---------- 211
 212 ----------------------------------------------------AEN-IMGK--------------------------G-V--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------GAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEEWIKAGK-PT-TP-GYVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYAY---RV---LGPW----------G-AG--Y------------TEG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------T-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----AVNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--A-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AA---------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VD------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---VNYSN--------AY-VR----------------LSG------TSMATPHVA----G---------------------------A------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQA---------- 212
 213 ----------------------------------------------------AEN-IMGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWIKAGK-PT-IP-GYVYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYAY---RV---LGPW----------G-AG--Y------------TEG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------A-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--T-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D-------------------------------------------------------------------------------------------------A---------------------------------------------------------------------------------------------------------------------------------TLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VD------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---VNYSN--------AY-VR----------------LSG------TSMATPHVA----G---------------------------A------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LNG-QNS----VYEVGAGRIDAYQA---------- 213
 214 --------------------------IDSKMADSIPQI-GVDKLH-------AEN-IKGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GVDY-N------H-------------P---------D--------------------------------L---------------------K----------------EAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYEDWINAGK-PE-YP-GYKYYTNHG-------TH-V-----------------------AGTIA----AQK-K-------------------------------NN------------ADYAVK-------------------GV--APE-V--DLYAY---RV---LGPW----------G-TG--S------------TEG-------------------------------------I--------LAG--------------I-----------DK---AI--------------------E-----D------G----------M----DV-----------------------------------------INMSLGAQ-----T-NDP---L--------------------Y---------------------------ATSV-----ATNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NA--------GP--------NEKTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--A-A----AL---------------------G---IS---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAMSIPTFSGSASNEKFENLQLLGKDFPDKLEDFGGQSFQIVFAGLGKEADFAGKDLNGKIALIQRGEITFDEKIKNAKKAGAKAVIVYNNVDGQIPAYLGEGVGLIPSFRLSKTDGERLKGLGEVSFKFEMLSNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VD------GNYDI---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------FS-TAP-----------------------------------------------------------------------------------------------EYINDPQ-DG---VNYSN--------AY-VR----------------LSG------TSMATPHVA----G---------------------------A------------------AA-L----IL----Q-------EHPEYT-----------------------------------------------------------------PFD--------------V---------------------KAAL-------MNT------------------------SDD------------------------------------------------------------------------LKG-DYS----VYEAGAGRIDAYQAV--------- 214
 215 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GI--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAM-----------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 215
 216 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A--------------------------------------------------------------------------------------------------------------------------------------IKTE-------------------------------------------------------------------------------------GD-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 216
 217 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPTKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------IKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 217
 218 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------I--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---DNYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 218
 219 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSA-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A--------------------------------------------------------------------------------------------------------------------------------------IKTE-------------------------------------------------------------------------------------GD-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 219
 220 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------I-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPL--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 220
 221 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------N----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPI--------AY-GR----------------MSG------TSMATPHTT----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 221
 222 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYN-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-Q-------------------------------NS------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NT--------GP--------EVGTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAMN---------------------------------------------------------------------------------------------------------------------------------SNTKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 222
 223 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYD-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-K-------------------------------NN------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAA-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A--I---------------------------------------------------------------------------------------------------------------------------------SNIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 223
 224 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-K-------------------------------NN------------VDYAVT-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 224
 225 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYE-GSAYYTSHG-------TH-V-----------------------AGTIS----ADK-K-------------------------------NN------------VDYAVN-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------EEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A----------------------------------------------------------------------------------------------------------------------------------------TE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 225
 226 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYD-GSAYYTSHG-------TH-V-----------------------AGTIS----ADK-K-------------------------------NN------------VDYAVT-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ARS----VFEVGSGRIDAYRAV--------- 226
 227 -----------------------------------------DKLH-------DEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------KQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYD-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-K-------------------------------NN------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPTYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 227
 228 ----------------------------------------------------AEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------EQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYD-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-K-------------------------------NN------------VDYAVK-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAA-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTIGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------------------------------------------------------NIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYLV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------VA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ERS----VFEVGSGRIDAYRAV--------- 228
 229 --------------------------VEPKMTDSVPQI-GVDKLH-------AEK-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DAYKGYRA-----------NQGEDPSKIDPNSIKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------V------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYKDWQNSGGYPEIYD-GSAYYTSHG-------TH-V-----------------------AGTIA----ADK-K-------------------------------NS------------VDYAVT-------------------GV--APD-V--DLYSY---RV---LGPY----------G-SG--Q------------TSG-------------------------------------I--------LAA--------------I-----------DK---AV--------------------K-----D------D----------M----DV-----------------------------------------INLSLGAS-----I-NDP---L--------------------Y---------------------------PTSV-----AVNN-A--------MLA----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------GEGTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-S--A-A----AL---------------------P---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------AAMTIPTFSADAGDLHVDKMMLLGKSFTDKIEVQGDVSLAFG-----------------------------------------------------------------------------------------ELSNIKTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------AT------KTDDI---K--------------------P------------D-----I------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------FS-TVP-----------------------------------------------------------------------------------------------EYINDPK-DG---ENYPV--------AY-GR----------------MSG------TSMATPHTA----G---------------------------V------------------AA-L----IL----Q-------EHPNYS-----------------------------------------------------------------PFE--------------V---------------------KEAL-------MNT------------------------AVD------------------------------------------------------------------------LKE-ARS----VFEVGSGRIDAYRAV--------- 229
 230 ------------------------QKAPQKLTDSIPQI-GVDKLH-------SEG-ITGK--------------------------G-I--KV--------------G--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------DVYKGYRA-----------KPGEDSSKVDPNSVKG----------------------------------------------------------------------------------------------------------------------------------------------------------------WDF--------------I------------NN-----------------------------------------------------------------------------------------D---A---------------------D-------P----------------------------------------------------------------------ME------------------------------------------TTYTEWQQSGA-PEFDDRGSSFYTAHG-------TH-V-----------------------AGIVS----AQK-K-------------------------------NT------------SDSAVK-------------------GV--APD-I--ELYNY---RV---LGPY----------G-SG--D------------SSG-------------------------------------I--------IAA--------------I-----------DK---SI--------------------S-----D------G----------M----NV-----------------------------------------INLSLGDD-----S-NNP---L--------------------D---------------------------PTSI-----AVNN-A--------MLS----GV-----V--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GP--------NPATLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--A-S----PF---------------------A---IT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------SSISLPKLSGHAGQLQFPNLILFGKNFTDKIEDFKGQT---------------------------------------------------------------------------------LPEQGNTSFTFDELSYIQTE-------------------------------------------------------------------------------------GD-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ADF-----S--S--------R-G---P--------------------VT------SNDDI---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VA--------------------------------V------------------------------------------------------------------LS-TVP-----------------------------------------------------------------------------------------------EYINDPQ-EG---ENYDV--------SY-ER----------------IQG------TSMASPHIA----G---------------------------V------------------AA-L----IL----Q-------EHPEYS-----------------------------------------------------------------PFD--------------V---------------------KTSL-------MNT------------------------ADD------------------------------------------------------------------------LKE-KYS----VYEVGAGRVDAYNAV--------- 230
 231 --------------------------------------------H-------AEG-YTGK--------------------------G-I--KV--------------G--------------------ILD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------L---------------------K----------------NAYKG-----------------------------G----------------------------------------------------------------------------------------------------------------------------------------------------------------YDF--------------V------------DD-----------------------------------------------------------------------------------------D---S---------------------N-------P----------------------------------------------------------------------ME------------------------------------------TTYADWKQSGK-PEMNG-SSAYYTNHG-------TH-V-----------------------AGIIG----SRGVA-------------------------------KD------------TEYTTV-------------------GA--APE-A--DIYAY---RV---LGPY----------G-SG--Q------------ADD-------------------------------------I--------IAA--------------V-----------DR---AV--------------------K-----D------D----------M----DV-----------------------------------------INMSLGNS-----L-NDP---L--------------------Y---------------------------ATSI-----AVNN-A--------VLS----GV-----T--------------------------------------------------------------------------------------T---------------VVAAG-NS--------GD--------KNYTLGS----------------------------------------------------------------------------------------------------------------------------------------------P-G--A-A----AL---------------------A---LS---VG--A------------------------------S-----------------------------S------------------------------------------------------------------------------------------------VAI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-ATF-----S--S--------R-G---P--------------------SR------MNYDI---K--------------------P------------E-----I------T-----------------G-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LS-TVP-----------------------------------------------------------------------------------------------FYVNDKTVDGTKPEDYKY--------AY-QR----------------LSG------TSMASPYVA----G---------------------------V------------------SA-L----LL----Q-------SNKSLQ-----------------------------------------------------------------PED--------------I---------------------KSIL-------MNT------------------------ADP------------------------------------------------------------------------LSK-AYS----VFEIGSGRVDAYEAI--------- 231
 232 ELSNELW----------------------------GLEAIGVTQQ-------LWE-EASG--------------------------TNI--IV--------------A--------------------VVD---------------------------T--------------GVDG-T------H-------------P---------D--------------------------------LEG--------------QVIAGYRPAFDEELPAGT-DS--------SYG---G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIA----AKKD--------------------------------GK------------GIV----------------------GV--APG-A--KIMPI---VIFDDPALV----------GGNG--Y------------VGD-----------------------------------DYV--------AAG--------------I-----------IW---AT--------------------D-----H------G----------A----KV-----------------------------------------MNHSWGGWGYSYT------MKE---------------------------------------------------------AFDY---------AMEH----GV-----V--------------------------------------------------------------------------------------M---------------VVSAG-NN--------TS---------DSHHQY----------------------------------------------------------------------------------------------------------------------------------------------PAGYPG-----------------------------V---IQ---V----------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------LD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YYGGTFRV-AGF-----S--S--------R-S--------------------------------------------------------------------------DGVS--V------G-----------------A-----P-------------G-----------------VT--------------------------------I------------------------------------------------------------------LS-TVP-----------------------------------------------------------------------------------------------GEDSIGYEGHNENVPATN------GGTY------DYYQ-----------G------TSMAAPHVT----G---------------------------V------------------VAVL----LQKF------------PNAK-----------------------------------------------------------------PWQ--------------I---------------------RKLL-------ENT-----------------------------------------------------------------------------------------------------AFDFNGNGWDHDTGYGLVKLDAALQ-------- 232
 233 -----------------------------------------VVRN-------GQT-LTGK--------------------------G-V--TV--------------A--------------------VVD---------------------------T--------------GIYP--------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RIIGFADMVNQKTEPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGDVA----SSGAS-------------------------------SS------------GQYR---------------------GP--APE-A--NLIGV---KV---LNKQ----------G-SG--T------------LAD-------------------------------------I--------IEG--------------V-----------EW---CI------------------------QYNEDNPDEP----------I----DI-----------------------------------------ISMSLGGDALRYDH-EQE---------------------------------------------------------------DPLV-RAVEE-AWSA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------DSQTIAS---------------------------------------------------------------------------------------------------------------------------------------PGVSEK-----------------------------V---IT---VG--A------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNTASS--DDDTV-ASF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IS----------------------------------------------------------------------------------------------------------LRSPNSYIDKLQKSSRVGSQY-FT----------------MSG------TSMATPICA----G---------------------------I------------------AALI----LQ------------HNPDLT-----------------------------------------------------------------PDE--------------V---------------------KELL-------KNG------------------------------------------------------------------------------------------------------TDKWKDEDPNIYGAGAVNAEN----------- 233
 234 -------------CSNIRKVYLNREVKALLDTATEASHAKEVVRN-------GQT-LTGK--------------------------G-V--TV--------------A--------------------VVD---------------------------T--------------GIYP--------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RIIGFADMVNQKTEPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGDVA----SSGAS-------------------------------SS------------GQYR---------------------GP--APE-A--NLIGV---KV---LNKQ----------G-SG--T------------LAD-------------------------------------I--------IEG--------------V-----------EW---CI------------------------QYNEDNPDEP----------I----DI-----------------------------------------MSMSLGGDALRYDH-EQE---------------------------------------------------------------DPLV-RAVEE-AWSA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------DSQTIAS---------------------------------------------------------------------------------------------------------------------------------------PGVSEK-----------------------------V---IT---VG--A------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNTASS--DDDTV-ASF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IS----------------------------------------------------------------------------------------------------------LRSPNSYIDKLQKSSRVGSQY-FT----------------MSG------TSMATPICA----G---------------------------I------------------AALI----LQ------------QNPDLT-----------------------------------------------------------------PDE--------------V---------------------KELL-------KNG------------------------------------------------------------------------------------------------------TDKWKDEDPNIYGAGAVNAENS---------- 234
 235 -----------------------------------------------------QT-LTGK--------------------------G-V--TV--------------A--------------------IVD---------------------------T--------------GIYP--------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RIIGFADMVNQKTEPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGDVA----SSGAS-------------------------------SS------------GQYR---------------------GP--APE-A--NLIGV---KV---LNKQ----------G-SG--T------------LAD-------------------------------------I--------IEG--------------V-----------EW---CI------------------------QYNEDNPDEP----------I----DI-----------------------------------------ISMSLGGDALRYDH-EQE---------------------------------------------------------------DPLV-RAVEE-AWNA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------DSQTIAS---------------------------------------------------------------------------------------------------------------------------------------PGVSEK-----------------------------V---IT---VG--A------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNTASS--DDDTV-APF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IS----------------------------------------------------------------------------------------------------------LRSPNSYIDKLQKSSRVGSQY-FT----------------MSG------TSMATPICA----G---------------------------I------------------AALI----LQ------------QNPDLT-----------------------------------------------------------------PDE--------------V---------------------KELL-------KNG------------------------------------------------------------------------------------------------------TDKWKD-------------------------- 235
 236 ------------------------------------------IRN-------NQA-LTGK--------------------------G-V--TV--------------A--------------------IVD---------------------------T--------------GIYE--------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RIKGFADFVNQKTDPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGDVA----SSGAS-------------------------------SS------------GQYR---------------------GP--APK-A--NLIGV---KV---LNKQ----------G-SG--T------------LAA-------------------------------------I--------IEG--------------V-----------EW---CI------------------------QYNEDNPDEP----------I----RI-----------------------------------------ISMSLGGEALRYDN-ELD---------------------------------------------------------------DPLV-KAVEE-AWNA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------DPQTISS---------------------------------------------------------------------------------------------------------------------------------------PGVSEK-----------------------------V---IT---VG--A------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDTVSR--EDDIV-ASF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------VS----------------------------------------------------------------------------------------------------------LRSPRSYIDKLQKSSRVGTQY-FT----------------MSG------TSMATPICA----G---------------------------I------------------AALI----LE------------HNPELT-----------------------------------------------------------------PDE--------------V---------------------KELL-------KNG------------------------------------------------------------------------------------------------------ADKWSDNDPNIYGAGAVNAEN----------- 236
 237 --------------------------------------------------------LTGK--------------------------G-V--TV--------------A--------------------VID---------------------------T--------------GIYQ--------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RITGFADFVNQRTEPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGDIA----SSGAS-------------------------------SS------------GKYQ---------------------GP--APE-A--NLIGV---KV---LNKS----------G-SG--T------------LAD-------------------------------------I--------IEG--------------V-----------EW---CI------------------------QYNKEYTENP----------I----RI-----------------------------------------ISMSLGGEALRYDK-ETD---------------------------------------------------------------DPLV-KAVEE-AWNA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------EAQTISS---------------------------------------------------------------------------------------------------------------------------------------PGVSQK-----------------------------V---IT---VG--A------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NDTPSN--EDDTI-ASF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VS----------------------------------------------------------------------------------------------------------LRSPRSYLDKLQKSNRVGSLY-FS----------------LSG------TSMATPICA----G---------------------------I------------------AALI----LQ------------QNPQLT-----------------------------------------------------------------PDE--------------V---------------------KTLI-------KQS------------------------------------------------------------------------------------------------------PDKWTNEDPNIYGAGAVNAENAV--------- 237
 238 -----------------------------------------------------QT-RTGK--------------------------G-V--TG--------------A--------------------VVD---------------------------T--------------GFYP--------H-------------L---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-------------------------RIMGFAEMVNQNTEPYDE-------------------------R--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-F-----------------------AGDVA----RRGPS-------------------------------SF------------GKYR---------------------GP--GRE-A--YLIGV---KV---FNKR----------G-SG--R------------LAD-------------------------------------F--------IEG--------------V-----------EG---CI------------------------QYNEDNPDEA----------I----DF-----------------------------------------MSMLLGGDALRYEH-EQE---------------------------------------------------------------DPLV-RAVEE-AWSA----GI-----V--------------------------------------------------------------------------------------V---------------CVAAG-NS--------GP---------------DWQTIGR---------------------------------------------------------------------------------------------------------------------------------------PGGSEK-----------------------------V---IT---VG--A------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNTASTFLDEETV-ASF-----S--S--------R-GPT-VYGKEKP----------------------------------------------------------------D-----F------L-----------------G-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------FP----------------------------------------------------------------------------------------------------------LRSGNSYFGKLQKSSRVGSQY-FS----------------MSG------TSMATPICA----G---------------------------I------------------AALI----LQ------------QNPDLT-----------------------------------------------------------------PDE--------------V------------------TVAKELL-------KNG------------------------------------------------------------------------------------------------------TEKWKDEDPNIYGAGAVNAE------------ 238
 239 ---------------------IAEDSLVKLQLHIATQEIASRKAN-------DLG-YTGK--------------------------G-I--TI--------------A--------------------FLD---------------------------T--------------GIYP--------H-------------P---------D--------------------------------F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKPKN-------------------------RIIAFYDVVNGKKQPYDD-------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGDAA----GNGYA-------------------------------SN------------GKYK---------------------GV--APE-A--NIVAV---KV---LDSY----------G-RG--S------------SSD-------------------------------------I--------LAG--------------M-----------QW---VL--------------------DNKEKYN-----------------I----RI-----------------------------------------VSLSIG---------ETPALPT---------------------------------------------------------FLDPLV-RGVDT-LWKN----GI-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GP---------------NYNSITS---------------------------------------------------------------------------------------------------------------------------------------PGTSRN-----------------------------A---IT---VG--A------------------------------V--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRTPDI--EDDEV-AKF-----S--G--------RGGPY-LY---KP----------------------------------------------------------------D-----V------V-----------------A-----P-------------G-----------------VK--------------------------------I------------------------------------------------------------------VS----------------------------------------------------------------------------------------------------------TASGNVPFG--ADEIMINKPY-RS----------------ATG------TSMATPMVA----G---------------------------A------------------VALL----LE------------KNSRLT-----------------------------------------------------------------NVE--------------I---------------------KNIL-------KTT------------------------------------------------------------------------------------------------------ATKINEAGLWTQGSGMINIEEALK-------- 239
 240 LDTATKWFGITKARS-------------------------------------DFG-VTGK--------------------------N-I--TI--------------A--------------------IID---------------------------T--------------GIDG-N------H-------------V---------D--------------------------------L---------------------S----------------G---------------------------------GKIIGWKDFI----------NNK----------------------------------------------------------------------------------------------------------------------------------------------------------TT------------PY-----------------------------------------------------------------------------------------D---D---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIAA----GT--------------------------------------------------------G-AGNSFY--------KGV--APD-A--LLVGI---KV---LDAN----------G-SG--S------------MST-------------------------------------V--------TAG--------------I-----------DW---AV----------------QNKDV-----Y------G----------I----KV-----------------------------------------INLSLGTSTS--SD-GT--------------------------D--------------------------STSL-----AVNR-A--------VDS----GI-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GP---------AKYTIG---S------------------------------------------------------------------------------------------------------------------------------------------P-G--A-A----EK---------------------A---IT---VA--A------------------------------M--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AD-------V--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GE---LGF------NL-ASF-----S--S--------R-G---P--------------------TADGR-------I---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------YN--------------------------------I------------------------------------------------------------------TA-A-K-----------------------------------------------------------------------------------------------ANS------------VNG--------YV-TY----------------S-G------TSMATPFVA----G---------------------------T------------------VA-L----ML----N-------ANPNLT-----------------------------------------------------------------PND--------------A---------------------KNII-------MST-------------------------AK------------------------------------------------------------------------SWGPP------------------S-KNVDYGAGRL 240
 241 MATYV-W---------------------------------------------NLG-YDGS--------------------------G-I--TI--------------G--------------------IID---------------------------T--------------GIDA-S------H-------------P---------D--------------------------------L---------------------Q--------------------------------------------------GKVIGWVDFV----------NGR----------------------------------------------------------------------------------------------------------------------------------------------------------SY------------PY-----------------------------------------------------------------------------------------D---D---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIAA----GT--------------------------------------------------------GAASNGKY--------KGM--APG-A--KLAGI---KV---LGAD----------G-SG--S------------IST-------------------------------------I--------IKG--------------V-----------EW---AV----------------DNKDK-----Y------G----------I----KV-----------------------------------------INLSLGSSQS--SD-GT--------------------------D--------------------------ALSQ-----AVNA-A--------WDA----GL-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GP---------NKYTIG---S------------------------------------------------------------------------------------------------------------------------------------------P-A--A-A----SK---------------------V---IT---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------YD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-TSF-----S--S--------R-G---P--------------------TADGR-------L---K--------------------P------------E-----V------V-----------------A-----P-------------G-----------------NW--------------------------------I------------------------------------------------------------------IA-A-R-----------------------------------------------------------------------------------------------ASGTSMG--Q----PIND--------YY-TA----------------APG------TSMATPHVA----G---------------------------I------------------AA-L----LL----Q-------AHPSWT-----------------------------------------------------------------PDK--------------V---------------------KTAL-------IET-------------------------AD------------------------------------------------------------------------IVKPD------------------EIADIAYGAGRV 241
 242 PSDRTPW-------GIEAIYRNPSIQ---------------------------ST-SGGK--------------------------G-I--RV--------------A--------------------VLD---------------------------T--------------GTYT-A------H-------------P---------D--------------------------------L---------------------S----------------A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NVEQCYNFT-TSSPVVNG------------CA-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIL----ANGGG-------------------------------G-------------SGI--W-------------------GV--APE-A--KLWSY---KV---LSDG----------G-SG--Y------------ADD-------------------------------------I--------AYA--------------I-----------RY---AA---------------DQGASN-----G------V----------K----VV-----------------------------------------ISMSLG---------SSV---K--------------------DS--------------------------LISN-----AVTY-A--------QQR----GA-----L--------------------------------------------------------------------------------------V---------------VAAAG-NS--------GP------------------SANTIGY------------------------------------------------------------------------------------------------------------------------------------P-G--A-L----KD---------------------A---VA---VA--A------------------------------LEN------------------------IQQN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------TY-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-ADF-----F--S--------R-GN--P--------------------ATAGDYVIQERDV-------------------------------------E-----V------S-----------------A-----P-------------G-----------------RA--------------------------------V------------------------------------------------------------------ES-TWN---------------------------------------------------------------------------------------------------------------NG--------GY-NS----------------ISG------TSMATPHIS----G---------------------------L------------------AA-K----IW----A-------SHPTWS-----------------------------------------------------------------NND--------------V---------------------RTEL-------QNR------------------------AKA------------------------------------------------------------------------N------DILGGISAAGGDDIASGFGFPTVQAGDQ 242
 243 ASQQIPW-------GIKAIYNNDTLT---------------------------CT-TGGS--------------------------G-I--NI--------------A--------------------VLD---------------------------T--------------GVNI-S------H-------------P---------D--------------------------------L---------------------V----------------N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NVEQCKDFTGATTPINNS------------CT-----------------------------------------------------------------------------------------D---R---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTAL----ADGGS-------------------------------DQ------------AGI--Y-------------------GV--APD-A--DLWAY---KV---LLDS----------G-SG--Y------------SDD-------------------------------------I--------AAA--------------I-----------RH---AA---------------DQATAT-----G------T----------K----TI-----------------------------------------ISMSLG---------SSA---N--------------------NS--------------------------LISS-----AVNY-A--------YSK----GV-----L--------------------------------------------------------------------------------------I---------------VAAAG-NS--------GY------------------AQGTIGY------------------------------------------------------------------------------------------------------------------------------------P-G--A-L----PN---------------------A---IA---VA--A------------------------------LEN------------------------VQQN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------TY-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-ADY-----S--S--------R-GY--I--------------------STAGDYVIQEGDI-------------------------------------E-----I------S-----------------A-----P-------------G-----------------SS--------------------------------V------------------------------------------------------------------YS-TWY---------------------------------------------------------------------------------------------------------------NG--------GY-NT----------------ISG------TSMATPHVS----G---------------------------L------------------AA-K----IW----A-------ENPSLS-----------------------------------------------------------------NTQ--------------L---------------------RSNL-------QER------------------------AKS------------------------------------------------------------------------V------DIKGGYGAAIGDDYASGFGFARVQ---- 243
 244 -----EW-------------------------------------K-------NFK-YKGE--------------------------G-M--VI--------------S--------------------IID---------------------------S--------------GIDY-R------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------KLSDPSKAKI-KNKNPEG-------------------------------------------------------------------------------------------------------------KGKYFTDKVPYGYNYADKNQNIIDTG---------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------MH-V-----------------------SGIVA----ANGNS-------------------------------DE------------VS--------------KFEAI---QGI--APE-A--QLFAM---KV---FSNDP-DYPSCNDED----------------------------------------------------------V--------VAA--------------I-----------TD---SV--------------------K-----L------G----------A----DV-----------------------------------------INMSLG------SD-AGFVKMT---------------------E--------------------------PIQK-----AVKM---------AEEN----GV-----V--------------------------------------------------------------------------------------V---------------VISAG-NS--------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTNPVKVP------------DIVDT---AI---IGAPS------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NM-SGF-----S--S--------W-GPA-P--------------------SL--------------------------------DFKP------------Q-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-TV----------------------------------------------------------------------------------------------------NDN-------------------NY-KY----------------MSG------TSMAAPHTS----G---------------------------I------------------MA-L----IL----Q-------RI-NSL-----------------------------------------------------------------DL-KLSPKDKVELVKNL-------------------------A-------INT---------------------------------------------------------------------------------------------SIPQVDEDSTEGKLPFSPRQQGAGLINALN----------- 244
 245 TDVLKEW-------------------------------------K-------NFK-YKGE--------------------------G-M--VI--------------S--------------------IID---------------------------S--------------GIDY-R------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------KLTDPSKAKL-KNKHPEG-------------------------------------------------------------------------------------------------------------KGKYFTDKVPYGYNYADKNQNIVDTG---------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------MH-V-----------------------SGIVA----ANGKA-------------------------------DE------------VS--------------KFEAI---QGI--APE-A--QLLAM---KV---FSNDP-DYPSCNDED----------------------------------------------------------V--------VAA--------------I-----------TD---SV--------------------K-----L------G----------A----DV-----------------------------------------INMSLG------SD-AGFVKMT---------------------E--------------------------PIQK-----AVKM---------AEDN----GV-----V--------------------------------------------------------------------------------------V---------------VISAG-NS--------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTNPKKVP------------DVVDT---AI---VGAPS------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------KE-------A------------------------------------------------------------------------------LSVASFENSKLNQLALTCTVGNKSTDFAYLASEISPINKLKSEYGIVDCNLGTKEDLKNKDIKGKIALIQRGENTFIEKKLNAQDAGAAGVIIYNKDGEKGYISMATDPNVTIPCMFITNEDGKALKDSISKDGKIKFDNKK---IRIDNPNKDNM-SDF-----S--S--------W-GPA-P--------------------SL--------------------------------DFKP------------Q-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-TV----------------------------------------------------------------------------------------------------NDN-------------------EY-KY----------------MSG------TSMAAPHTS----G---------------------------I------------------MA-L----IL----Q-------RI-NSL-----------------------------------------------------------------NL-KLSPKDKVELAKNL-------------------------A-------MNT---------------------------------------------------------------------------------------------SIPQVDEDSTESKLPFSPRQQGAGLI--------------- 245
 246 -----EW-------------------------------------K-------TFN-YKGE--------------------------G-M--VI--------------S--------------------IID---------------------------S--------------GIDY-R------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------KLTDPSKAKI-KNKNPKG-------------------------------------------------------------------------------------------------------------NGKYYTDKIPYGYNYADKNDNIIDTG---------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------MH-V-----------------------AGIVA----ANGKT-------------------------------DE------------VS--------------KFEAI---QGI--APE-A--QLLAM---KV---FSNDP-DYPSCNDED----------------------------------------------------------V--------VNA--------------I-----------ND---SV--------------------R-----L------G----------A----DV-----------------------------------------INMSLG------SD-AGFVKIT---------------------E--------------------------PIQN-----AVKQ---------AELK----GV-----V--------------------------------------------------------------------------------------V---------------VISAG-NS--------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTSPKKVP------------GIVDT---AI---VGSPS------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------KE-------A------------------------------------------------------------------------------LSVASFENTKLNQK------------------------------------------------------------------------------------------------------------------------------------------KNTM-SDF-----S--S--------W-GPA-P--------------------SL--------------------------------DFKP------------Q-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-TA----------------------------------------------------------------------------------------------------NDD-------------------KY-KY----------------MSG------TSMAAPHTS----G---------------------------I------------------MA-L----VL----Q-------HL-KTL-----------------------------------------------------------------QLNNLTPMQKVELAKNL-------------------------V-------INT---------------------------------------------------------------------------------------------SVPQIDKDSKNSSLPYSPRKQGSGLIDAL------------ 246
 247 TNVLKEW-------------------------------------K-------TFN-YKGE--------------------------G-M--VI--------------S--------------------IID---------------------------S--------------GIDY-R------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------KLTDPSKAKI-KNKNLQG-------------------------------------------------------------------------------------------------------------KGRYYTDKIPYGYNYADKNDNIIDTG---------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------MH-V-----------------------AGIVA----ANGKI-------------------------------DE------------VS--------------KFEAI---QGI--APE-A--QLLAM---KV---FSNDP-DYPSCNDED----------------------------------------------------------V--------VNA--------------I-----------ND---SV--------------------R-----L------G----------A----DV-----------------------------------------INMSLG------SD-AGFVKMT---------------------E--------------------------PIQN-----AVKQ---------AENK----GV-----V--------------------------------------------------------------------------------------V---------------VISAG-NS--------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSTSPKKVS------------GVVDT---AI---VGSPS------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------KE-------A------------------------------------------------------------------------------LSVASFENTKLNQQALTYISNNKSKDIAYLTSEINPIDKLKSDYDIVNCGLGTKKDFQNNKVKGKIALVQRGENTFIEKKLNAQDAGAVGVIVFNKDNEKGYIGMATDPNVTIPAIFVTNEDGKELKNAISTGVKIKFSNKK---IRIDNPNKNAM-SDF-----S--S--------W-GPA-P--------------------SL--------------------------------DFKP------------Q-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-TA----------------------------------------------------------------------------------------------------NDD-------------------KY-KY----------------MSG------TSMAAPHTS----G---------------------------I------------------MA-L----VL----Q-------HL-KTL-----------------------------------------------------------------QLNNLTPMQRVELAKNL-------------------------V-------INT---------------------------------------------------------------------------------------------SMPQIDKDSKNSSLPYSPRKQGSGLI--------------- 247
 248 VEAQKAW-------------------------------------E-------ATG-YKGE--------------------------G-M--VV--------------G--------------------IID---------------------------T--------------GIDY-N------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------VLTDTSNEKL-TKEKVEEIT------------------------------------------------------------------------------------------------------KANNLPGKFYTDKVPYGYNYMDKNDEIRDLGSGA------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------MH-V-----------------------AGTVG----ANGDE-------------------------------NN------------------------------GGI---QGV--APE-A--QLLAL---KV---FGNDP-EMPFTFGDV----------------------------------------------------------Y--------VKA--------------I-----------DD---AI--------------------K-----L------G----------A----DV-----------------------------------------LNMSLG------ST-AGFVSAD---------------------D--------------------------PEQQ-----AVKR---------AVDN----GV-----L--------------------------------------------------------------------------------------M---------------SISAG-NS--------AY------------------------------------------------------------------------------------------------------------------------------------------------------------------F-GNGYYTSPLVFA------------DNPDY---GV---SGSPG------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------YE-------S------------------------------------------------------------------------------IQVASYENSFMDVDALQYDINNDS----------------------------------------------------------------------------------------------------------GKTVKITFTGDK---QKIDNPSAGKM-SDF-----T--S--------W-GLA-P--------------------NL--------------------------------DFKP------------E-----I------T-----------------A-----P-------------G-----------------GQ--------------------------------I------------------------------------------------------------------LS-TL----------------------------------------------------------------------------------------------------NNN-------------------QY-GI----------------MSG------TSMAAPHVS----G---------------------------G------------------AA-L----VL----E-------RVDKDF-----------------------------------------------------------------QLKN---ADRVLMAKNL-------------------------L-------MNT---------------------------------------------------------------------------------------------AKP-----VQQNGVFVSPRRQGAGLMQLNAALS-------- 248
 249 ANVQAVW-------------------------------------S-------NYK-YKGE--------------------------G-T--VV--------------S--------------------VID---------------------------S--------------GIDP-T------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------RLSDDKDVKL-TKSDVEKFT------------------------------------------------------------------------------------------------------DTVK-HGRYFNSKVPYGFNYADNNDTITDDKVD-------------------------------------------------------------------------------------------------------------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------QHG-------MH-V-----------------------AGIIG----ANGTG-------------------------------DD------------PA----------------KSV---VGV--APE-A--QLLAM---KV---FSNSD-TSAKTGSAT----------------------------------------------------------V--------VSA--------------I-----------ED---SA--------------------K-----I------G----------A----DV-----------------------------------------LNMSLG------SN-SGNQTLE---------------------D--------------------------PELA-----AVQN---------ANES----GT-----A--------------------------------------------------------------------------------------A---------------VISAG-NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTSG------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------TE-------G------------------------------------------------------------------------------VNKDYY---------------------------------------------------------------------------------------------------------------------------------------------------DKM-SDF-----T--S--------Y-GPV-S--------------------NL--------------------------------SFKP------------D-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------WS-TQ----------------------------------------------------------------------------------------------------NNN-------------------GY-TN----------------MSG------TSMASPFIA----G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 249
 250 ANVQAVW-------------------------------------S-------NYK-YKGE--------------------------G-T--VV--------------S--------------------VID---------------------------S--------------GIDP-T------H-------------K---------D--------------------------------M--------------------------------------------------------------------------------------------RLSDDKDVKL-TKSDVEKFT------------------------------------------------------------------------------------------------------DTAK-HGRYFNSKVPYGFNYADNNDTITDDTVD-------------------------------------------------------------------------------------------------------------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------QHG-------MH-V-----------------------AGIIG----ANGTG-------------------------------DD------------PA----------------KSV---VGV--APE-A--QLLAM---KV---FTNSD-TSATTGSST----------------------------------------------------------L--------VSA--------------I-----------ED---SA--------------------K-----I------G----------A----DV-----------------------------------------LNMSLG------SD-SGNQTLE---------------------D--------------------------PELA-----AVQN---------ANES----GT-----A--------------------------------------------------------------------------------------A---------------VISAG-NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTSG------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------TE-------G------------------------------------------------------------------------------VNKDYYG-------------------------------------------------------------------------------------------------------------------------------------------------EDKM-SDF-----T--S--------Y-GPV-S--------------------NL--------------------------------SFKP------------D-----I------T-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------WS-TQ----------------------------------------------------------------------------------------------------NNN-------------------GY-TN----------------MSG------TSMASPFIA----G---------------------------S------------------QA-L----LK----Q-------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 250
 251 ANVSTVW-------------------------------------N-------NYK-YKGE--------------------------G-T--VV--------------S--------------------IID---------------------------T--------------GIDP-N------H-------------K---------D--------------------------------L--------------------------------------------------------------------------------------------RLSDDSKVKL-TKDKVNAFT------------------------------------------------------------------------------------------------------KESG-YGRYFTDKVPYGHNYSDNNDNITDDNPS-------------------------------------------------------------------------------------------------------------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------QHG-------MH-V-----------------------AGIVA----ANGTA-------------------------------DS-------------V----------------NSV---VGV--APE-A--QLLAM---KA---FSNSD-SSASTDSTS----------------------------------------------------------I--------IGA--------------I-----------DD---SA--------------------K-----L------G----------A----DV-----------------------------------------LNMSLG------SV-SGEQTED---------------------D--------------------------PEVA-----AVER---------ATKK----GT-----A--------------------------------------------------------------------------------------A---------------VISAG-NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTSN------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------------------------------------------------------------------------------------IE-------G------------------------------------------------------------------------------VNKAYQ--------------------------------------------------------------------------------------------------------------------------------------------------TDLM-SDF-----T--S--------Y-GPT-S--------------------SL--------------------------------AFKP------------D-----I------S-----------------A-----P-------------G-----------------GH--------------------------------I------------------------------------------------------------------WS-TQ----------------------------------------------------------------------------------------------------NNN-------------------GY-TN----------------MSG------TSMASPFIA----G---------------------------T------------------QA-L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 251
 252 AQVQDVW-------------------------------------Q-------EQK-LKGE--------------------------G-M--VI--------------S--------------------IID---------------------------T--------------GIDS-S------H-------------Q---------D--------------------------------L--------------------------------------------------------------------------------------------KLDSGVSTAL-SKSEVESDK------------------------------------------------------------------------------------------------------SKLG-HGKYYTEKVPYGYNYADKNDQIVDNGCG-------------------------------------------------------------------------------------------------------------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------MHG-------QH-V-----------------------AGIAG----ANGQ------------------------------------------------------------------V---KGV--APD-A--QLLAM---KV---FSNNA-KNSGAYDDD----------------------------------------------------------I--------ISA--------------I-----------ED---SV--------------------K-----L------G----------A----DV-----------------------------------------INMSLG------SV-SSDVGPS---------------------D--------------------------PQQQ-----AVAK---------ASEA----GV-----I--------------------------------------------------------------------------------------N---------------VISAG-NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVAG------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------AD-------G----------------------------------------------------------------------------NPVNNTFWLKQQKKVRASRLKFGTAL---------------------------------------------------------------------------------------------------------------------------IDNSRAGKM-SDF-----T--S--------W-GPT-P--------------------EL--------------------------------DFKP------------E-----I------T-----------------A-----P-------------G-----------------GK--------------------------------I------------------------------------------------------------------YS-LA----------------------------------------------------------------------------------------------------NDN-------------------KY-QQ----------------MSG------TSMASPFVA----G---------------------------S------------------EA-L----IL----Q-------GIKK-------------------------------------------------------------------QGLNLSGEELVQFAKNS-------------------------A-------MNT---------------------------------------------------------------------------------------------SHPVYD--TEHTKEIISPRRQGSGEINVKDA---------- 252
 253 IKADTLW-------------------------------------D-------QYD-FSGQ--------------------------G-M--LI--------------S--------------------IID---------------------------T--------------GVDP-T------H-------------N---------D--------------------------------M--------------------------------------------------------------------------------------------KLSPEIESKYKSKDAVDKVI------------------------------------------------------------------------------------------------------KENGLKGRWYSRKVPYGYNYADESDEIRDSGIG-------------------------------------------------------------------------------------------------------------------------------------G--------------------------------------------------------------------------------------------------------------------------------------------------YHG-------MH-V-----------------------AGIVA----ANGDT-------------------------------KT------------------------------GGV---RGV--APN-A--QLLGM---KV---FSNDA-LVSTVYEEV----------------------------------------------------------W--------LKA--------------I-----------DD---SV--------------------K-----L------G----------A----DV-----------------------------------------LNMSLG------MG-SGYSREG--------------------VS--------------------------PTNE-----AFRK---------AKAA----GV-----V--------------------------------------------------------------------------------------C---------------AVAMG-ND---------R------------------------------------------------------------------------------------------------------------------------------------------------------------------V-TNWGGEGKTNLA------------INPDF---GT---TGHPA------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------DP-------S------------------------------------------------------------------------------YSVASMEQKTKPDQQINITPVHS----------------------------------------------------------------------------------------------------------------------------VNNPKGRQM-SEF-----S--S--------W-GIT-P--------------------DL--------------------------------RLKP------------D-----I------A-----------------G-----V-------------G-----------------GQ--------------------------------I------------------------------------------------------------------YS-TI----------------------------------------------------------------------------------------------------NDN-------------------KY-TM----------------MSG------TSMATPQVA----G---------------------------A------------------SA-L----VM----Q-------RLYKDG-----------------------------------------------------------------WLKKTEDGKPDPMQEYLT---------------------VLVM-------MNT---------------------------------------------------------------------------------------------ATPVKDTEVDDASL-YTPKQQGAGLVNL------------- 253
 254 SQDLVSEPTTTELADTDAASMANTGSDATQKSASLPPVNTDVHDWVKTKGAWDKG-YKGQ--------------------------GKV--VA-----------------------------------VID---------------------------T--------------GIDP-A------HQSMRISDVSTAKVK---------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEDMLARQKAAGINYGSWINDKVVFAHNYVENSDNIKENQFEDFDEDWENFEFDAEAEPKAIKKHKIYRPQ-STQAPKETVIKTEETDGSHDIDWTQTDDDTKYE---------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------MH-V-----------------------TGIVA----G----------------------------------------------------NSKEAAATGERFL---------GI--APE-A--QVMFM---RV-----------------------F------------AND-------------------------------------I--------MGSAE----------SLF--------------------------------------------------------------IKAIEDAVALGAD-------V---------------------------INLSLGTANGAQ-------------------------------------------------------------------LSGSKPLMEAIEKAKKA----GV-----S--------------------------------------------------------------------------------------V---------------VVAAG-N------ERVYGS-----DHDDPLATN----------------------------------------------------------------------------------------------------------------------------------------------PGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EMNH------F-----S--N--------W-GLTSDGYLKP-----------------------------------------------------------------D-----I------T-----------------A-----P-------------G-----------------GD--------------------------------I------------------------------------------------------------------YS-------------------------------------------------------------------------------------T---YNDNHYG-------------------------------------------------SQTG------TSMASPQIA----G----------------------------------------------ASLLVKQYLE-------------------------------------------------------------------------------------KT----QPNLPKEKIA------------------DIVKNLL-------MSN------------------------------------------------------------------------------------------------AQIHVNPETKTTTSPRQQGAGLLNIDGA---------- 254
 255 GNVQSAW-------------------------------------D-------Q-G-YRGE--------------------------H-T--VV--------------A--------------------VID---------------------------S--------------GVD--V------H-------------H---------K--------------------------------D--------------------------------------------------------------------------------------------FLTMPKNPKL-TADQMKRLI------------------------------------------------------------------------------------------------------KRLG-YGRYVNEKFPFAYNYVDNENDHLKAP-NG------------------------------------------------------------------------------------------------------------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------PHG-------QH-V-----------------------SGIIA----ADG-H-------------------------------PD------------G---------------DNTYV---VGV--APE-A--QLMQL---KV---FGDNS-T-----SLD----------------------------------------------------------M--------AKE--------------I-----------CD---AV--------------------N-----L------G----------A----DV-----------------------------------------INMSLG------GG-VSAADLN---------------------I--------------------------QDQR-----AVQY---------AVDH----GV-----V--------------------------------------------------------------------------------------V---------------VISAA-NN--------GN------------------------------------------------------------------------------------------------------------------------------------------------------------------A-ASVDNPTHLTDLDNYQAGGNAGNYNPFSS---ST---VANPG------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------RS-------A------------------------------------------------------------------------------ITVAAETSGTGK--------------------------------------------------------------------------------------------------------------------------------------------DSDM-AFF-----S--S--------W-GPL-P--------------------DF--------------------------------TLKP------------D-----V------S-----------------A-----P-------------G-----------------YD--------------------------------V------------------------------------------------------------------IS-TA----------------------------------------------------------------------------------------------------NGN-------------------SY-TQ----------------MSG------TSMASPFVA----G---------------------------A------------------AA-L----VR----E-------RLLKTN-----------------------------------------------------------------P--KLKGAALVEAIKAL-------------------------L-------TNT---------------------------------------------------------------------------------------------ADPQVQ--NGY-NTLVSPRRQGAGQINVGAA---------- 255
 256 GNVKGLW-------------------------------------N-------E-G-YQGQ--------------------------G-M--VV--------------A--------------------VID---------------------------S--------------GVQ--A------H-------------D---------D--------------------------------L--------------------------------------------------------------------------------------------RLSDDSTAAI-TKEKAEAAI------------------------------------------------------------------------------------------------------SKLG-YGSYVNSKIPFAYDYVNNDSVNTGTTVAG------------------------------------------------------------------------------------------------------------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------THG-------EH-V-----------------------AGIIA----ANGTT-------------------------------AD------------GATGNE---------KATTYV---KGV--APE-A--QILAM---QVIDEFADEN-A-----N-D----------------------------------------------------------I--------SRA--------------I-----------RD---AV--------------------T-----L------G----------A----NA-----------------------------------------IQMSLG------IG-VTEQDLT---------------------D--------------------------EEQA-----AVQY---------ATDH----GV-----F--------------------------------------------------------------------------------------V---------------SISAG-NN--------AN------------------------------------------------------------------------------------------------------------------------------------------------------------------A-GSIIGSKTSNDI--------STAYSPKND---ST---IGDPG------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------AS-------A------------------------------------------------------------------------------MTVAAEKSATGD--------------------------------------------------------------------------------------------------------------------------------------------KSEM-DGF-----S--S--------W-GPM-A--------------------DY--------------------------------TLKP------------D-----I------S-----------------A-----P-------------G-----------------DN--------------------------------V------------------------------------------------------------------IS-TAI-----------------------------------------------------------------------------------------------DPTTNTQ-------------------TY-AT----------------ESG------TSMAGPYNA----G---------------------------A------------------AL-L----VM----Q-------KIKATR-----------------------------------------------------------------P--DLQGADLVKAVKLA-------------------------L-------MNA---------------------------------------------------------------------------------------------ADPMKD--INYPDTYISPRRQGAGQIDVSKAGD-------- 256
 257 ----------------------------------------LDDIKVPALRKRVAGKGLGE--------------------------D-T--IV--------------A--------------------IID---------------------------T--------------GIDT-S------H-------------PVFQDRVIFWN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DATREGRSPLTRSRQLDGKIELEHNKFVALPEKIKENEYVFSGYIDEKKLGFQQGDLWTTLGKEGVDINRNGTKDDKLLVVVGIIPNPELAKLEEASKKAAEERKAAAAKDEPIPAEKPDLEKRDLTKEYALAFVDVDMDGKFSKEEADTPIMDFNSARKMQREDLKPPYQIMLEFPSRTKRIAYPLLFRPNAKKQVTEITVAFDQQ-----------------------------------------------------------------------------SHG-------TH-V-----------------------AGIVA----GSGLQ--------------------------------------------------------------------IEGA--APK-A--QLMAI---KV---CSGRS-CTDQAILRG----------------------------------------------------------I--------VSA-------------------------------------------------------------------------FFNPQGYVPDV-----------------------------------------VNISLGSHEG---------------------------------------------------------------------YVKRPLSILIQDLSAKF----GT-----T--------------------------------------------------------------------------------------F---------------FISAS-NDG----------------------------------------------------------------------------------------------------------------------------------------------------------------------PGY------------------------------------RTINGLGGSS------------------------------P-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AVFVGAHVSANTLREHYRLAE-GVNAPEHGLLYFSSLGPSYTG------------------------------------------------------EMRPNVV------------------------A-----P-------------G-----------------SA---------------------------------------------------------------------------------------------------LS---------------------------------------------------------------------------------------------------------------------------------------STPLNSDGSSMFNG------TSMSSPIAA----G---------------------------A------------------AAAM----LSLIKADKEYAKVLERQEKK----------------------------------------------------------------------------------I------------------EAIRKKS-------SDS------------------------------------------------------------------------------------KYSLTSLALSMRLALENSALRMKGFTYAQQGAGLIDIDKAY--------- 257
 258 ---------------------------------SVPLIGATDVWS-------NYG-ADGS--------------------------G-L--YL--------------G--------------------VVD---------------------------T--------------GIDY-T------H-------------P---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-----------------------------------------------------------------------------------------DGTNHGFPTSKVVAGYDFGDNDSDPMDLQ------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIMA----ADGVV-------------------------------K--------------------------------------GV--APK-A--KLVVA---KI---VKGG------------EG--Y------------ATG-------------------------------------IDIARAFDYMGDPDNLDNGPEGKHPKV-------------------------------------------------------------------TA-----------------------------------------VNMSFGSPYGFVDP-FDIEHM----------------------------------------------------------AIER---------CIGT----GV-----F--------------------------------------------------------------------------------------V---------------SLSAG-NS-------YWAYANTFGTSYRYQYIPDWASVGS---------------------------------------------------------------------------------------------------------------------------------------P-SITPSAMSVAASYNSYSRYPALTRIAPTPEVNYA---YT---VG--S------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------PITTLGDNNGQGYEYVYCGYGGSSEFPPEVSGKIALIRRGNYTFLTKIQNAYNAGAIGVIIFNNTTGYLTMATDGQPSIPAVFISKADGEALLPYAVNGETGGGRVGFRSNTYADVPQLVDTM------------------------VSF-----S--S--------W-GPA-P----------------------------------------------------------------------D-----LSFKPEIT-----------------A-----P-------------G-----------------GG--------------------------------I------------------------------------------------------------------WS-TVP---------------------------------------------------------------------------------------------------------------------VAQGSY-AN----------------YSG------TSMAAPHVA----S----------------------------------------------AAAL----VK----Q-------VHPNWQ-----------------------------------------------------------------VSD--------------I---------------------KTAL-------MNT------------------------------------------------------------------------------------------------AKLITDPSTGVYYSPHLVGAGRVDVKSAV--------- 258
 259 ----------------------------------------------------------------------------------------M--VI--------------S--------------------NID---------------------------T--------------GTDY-R------HKAMRIDDDAKASMRFKKEDLKGTDKNYWLSDKIPHAFNYYNGGKITVEKYDDGRDYF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------PHG-------MH-I-----------------------AGILA----GNDTEQDIKNFNGID------------------------------------------------------------GI--APN-A--QIFSY---KM------------------------------------YSD-------------------------------------A--------GSG--------------FAGDETMFHAIEDS-------------------------------------------------IKHNVDV-----------------------------------------VSVSSG-------------------------------------------------------------------------FTGTGLVGEKYWQAIRALRKAGI-----P--------------------------------------------------------------------------------------M---------------VVATG-NY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATSASSSSWDLVANNHLKMTDTGNVTRTAAHEDA---IA---VASAKNQTVEFDKVNIGGESFKYRNIGAFFDKNKIT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNEDGTKAPSKLKFVYIGKGQDQDLIGLDLRGKIAVMDRIYTKDLKNAFKKAMDKGARAIMVVNTVNYYNRDNWT--ELPAMGYEADEGTKSQVFSISGDDGVKLWNMINPNKKTEVKRNNKEDFKDKLEQYYPIDMESFNSNKPNVGDEKEIDFKFAPDTDKELYKEDIIVPAGSTSWGPRIDLLLKPDVS--A-----P-------------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNIKSTLNVINGKSTYGYMSG------TSMATPIVA----A----------------------------------------------STVLIRPKLKEMLERPVLKNLKGDDKID----------------------------------------------------------------------------------L------------------TSLTKIA-------LQN------------------------------------------------------------------------------------------TARPMMDATSWKEKSQYFASPRQQGAGLINVANALRNEVVATFK 259
 260 ----------------------------------------------------------GK--------------------------G-V--LV--------------G--------------------FID---------------------------S--------------GIAYTH--------------------P---------A--------------------------------FMDSEGNTRIEYIYDLS----------------LEKKVYDKDIINKAIK----SNDPYSIVPVLDNT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAC---------------------------------------------------------------------AGGKINDVYKGA--APE-A--SIAMV---K-----AAR------------GSWIL------------SSQ-------------------------------------I--------MQG--------------IKFLIDKSKERNMP------------------------------------------------------LV-----------------------------------------INMSLSTNNGAHNG-SSLLEQY-------------IS-TVSNLE--------------------------------------------------------RA-----T--------------------------------------------------------------------------------------I---------------VIAAG-NEGDA--AHHTGGELDE---TQ----TKTFNVASDENTVVINLYKSILPDVSLNIISPTGQSSGNIN------------VQEGYFHGGI-GRDRYDIYVAGPKPFELNSEVKIIISSIGSSYLITGVWKIQITVRNNYKGSFSMWLPISEGLNPQTKFLEPINYNTLGIPATVDN-----------------------------V---IA---VG--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NSLTNTLSSFSGRGQQTQGNIIRP--------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LG-----------------------------------------------------------------------------------------------------------------------------------------PIPNGGYDSKTG------TSMAAPQVS----G---------------------------I------------------CALI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 260
 261 --------------------------IELPKNLYEADSEGNRATCVPQAVST--YNLSGK--------------------------G-V--LV--------------G--------------------FID---------------------------S--------------GIAYTH--------------------P---------A--------------------------------FMDSDGNTRIEYIYDLS----------------LGRKVYDKETINKAIK----SNDPYSIVPVLDNT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAC---------------------------------------------------------------------AGGKINSVYKGA--APE-A--SIAMV---K-----AAR------------GSWIL------------SSQ-------------------------------------I--------MQG--------------IKFLIDKSKEINMP------------------------------------------------------LV-----------------------------------------INMSLSTNNGAHNG-SSLLEQY-------------IS-TVSNLE--------------------------------------------------------RA-----T--------------------------------------------------------------------------------------I---------------VIAAG-NEGDA--AHHTGGELDQ---TQ----TKAFNVASDESTVVINLYKSILPDVSLNIISPTGQSSGNIN------------IQEGYFHGGI-GRDRYDIYVSGPKPFELNSEIQIIISSISSEYLIEGVWKLQITTLNNYKGSFSIWLPISEGLNPKTKFLEPINYNTLGIPATVDN-----------------------------I---IA---VG--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NSLTNTLSSFSGRGPQIQSNIIRP--------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LG-----------------------------------------------------------------------------------------------------------------------------------------PIPNGGYDSKTG------TSMAAPQVA----G---------------------------I------------------CALIMQFGIVNG----------NDPYLF----------------------------------------------------------------------------------G------------------QRLKYYL-------VRG---------------------------------------------------------------------------------------------------ANRARTDIEYPNPLWGYGTACAYDSL--------- 261
 262 --------------------------IELPKILYTSAYDSNRASCIPSVWNN--YNLTGE--------------------------G-I--LV--------------G--------------------FLD---------------------------T--------------GIDYTH--------------------N---------A--------------------------------FKDDEGNTRIEYIYDLE----------------NG-VVYDKNKINEALK----SEDPFSIVPEIDLS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAC---------------------------------------------------------------------AGGNINFDNYGV--AYK-S--SIAMV---KITGENSLR------------AA--L------------STQ-------------------------------------L--------MRG--------------LKFLMDKSNEINKP------------------------------------------------------LV-----------------------------------------VNISLSTNDGSHNG-SSLLEKY-------------IQ-TFTQLQ--------------------------------------------------------KA-----V--------------------------------------------------------------------------------------I---------------VVAAG-NEGNS--AHHVGGKMKK---EE----DLDLNIGDGEKGIILDFFKPVLVDVSVEVISPTGISTGPMG------------LSESYKERFV-GREKIVVYSTGPKPFDIQGQTTISILPLGDT-ITSGGWRIIVRKLNNYEGYFDVWLPIAEGLNERTRFLQPSVYNTLGIPATVEG-----------------------------V---IS---VG--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y--NFLNNNLSAFSGRGVVRPEWLIKP--------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------LS-----------------------------------------------------------------------------------------------------------------------------------------TVEEQGFDTKSG------TSMAAPQVS----G---------------------------I------------------CALLFEWGIIRN----------NDPFLY----------------------------------------------------------------------------------G------------------ERIKYYL-------IKG---------------------------------------------------------------------------------------------------AKRTIFGEAYPNPDLGYGFVCLDRTME-------- 262
 263 -------IKPSRKLHLRMDTAMGAVKLPEFQNKT--------------------G-LTGK--------------------------G-V--II--------------G--------------------IID---------------------------S--------------GI----------------------------------D--------------------------------P---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHPAFAGRILHIWDQTLPGPGVTEGGYGAEFTG--------------------------------------------------------------------------AQLTISQ---------DTG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AG-IA----AGADA-------------------------------S--------------YG----------------------GV--APE-A--ELIVV---RS-------------------DLQDA--------------H-------------------------------------I--------ADG--------------V-----------RY--IFR--------------------------IARELGRA---------------AV-----------------------------------------VNLSLGGHADAHDG-SDSLSK----------------------------------------------------------VIDA-----------ET--GPGR-----I--------------------------------------------------------------------------------------V---------------CCAAG-NE-------------------------GNDNIGS---------------------------------------------------------------------------------------------------------------------------------------P-GAASSA-------------------------------IT---VA--A------------------------------YTTKTKYTDIDNQVREMGLELHTI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SEF-----S--S--------E-GPL-RNDSHKP----------------------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------AM--------------------------------I------------------------------------------------------------------ISTLSA----------------------------------------------------------------------------------------------------------------------------DANFDRSSMINSKF--VVQAG------TSMATPFVS----G---------------------------L------------------VALL----------LQ------RDPNLE-----------------------------------------------------------------PTA--------------V---------------------KDLL-------RKN---------------------------------------------------------------------------------------------------SAIPGKPAGTFDEKWGYGVIN-------------- 263
 264 ------------TWGLDRLDQDSIRYDHHYTTP-CGLTG-----K-----------------------------------------G-V--DV--------------Y--------------------VLD---------------------------S--------------GIFY-E------H-------------K---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QGRASSPGCDPIDQ----IFNTSKNGADFTGHG-------TH-V-----------------------AGTVG----GKK-----------------------------------------------------------------------FGV--APG-V--NLFSV---RV---LDTQ----------NSGS---------------ANS-------------------------------------L--------VLG--------------AECVVKSVERRKRP------------------------------------------------------SI-----------------------------------------VNLSIY----------------------------------------------------------------GDKNLLVKRALDTLM-------------RKGI-----T--------------------------------------------------------------------------------------V---------------IGIAG-NSKTK--------------------------------------------------------------------------------------------------------------------------------------------------------------------PKNSCKVGPGSIQG---------------------I---IT---AS--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STKS-DEPLMYSNAGTCVD----------------------------------------------------------------------------L------Y-----------------A-----P-------------G-----------------AE--------------------------------I------------------------------------------------------------------LSASTNC---------------------------------------------------------------------------------------------------------------------------------------KNCRSTRQG------SSMAAPHVT----G---------------------------A------------------VALL----LE------------KCPTMK--------------------------------------------------------------------------------------------------------PWRVKYILRSQMTKENKLNFSRMPRIYQSMTPNLLLHTSSLQCDLEC----------------------------------------------------------------------------------------------------- 264
 265 S----------DIAVTLTRSLTTVKADAAQRA---------FHAL-------------GE--------------------------GIV--WA-----------------------------------VLD---------------------------S--------------GVDG-R------H----------AHFA---------E--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQTLHGRIDSLGV----------------------------------------------RTPIEHRDYTPDGDAQNP---------TPG----DATLRDNATQRTGHASALVDRL-----------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIS----GYWTT---------------------------------EEKGGLRVVGTEMRDENSGAGSTSKPLISRETLTSISGV--APL-S--KVVSL---KV-----------------------I------------A-D-------------------------------------V--------TRTDDFKQTRGQGKVSWV--------------------------------------------------------------LRAIDDIQKWNQNGRRLLIHG---------------------------VNMSIGYDFDPRWF-----------------------------------------------------------------ACGQSPLCAEVNRLVKS----GV-----C--------------------------------------------------------------------------------------V---------------VVSAG-NSGYS--SYISGSGTELNSYNNLSITD----------------------------------------------------------------------------------------------------------------------------------------------PGN--------------------------------AELAIT---VG--S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THRDMPHLYGVSYF-----S--S--------R-GPTGDGRRKP-----------------------------------------------------------------D-----L------L-----------------A-----P-------------G-----------------ER--------------------------------I------------------------------------------------------------------RS-------------------------------------------------------------------------------------CAAGIEQERYGVDPEIHPSPKVEAAKPKKPGTLAHAVEGPPQPLQPNADRAPENGKVLYCEQTG------TSMAAPHVS----G----------------------------------------------A---IAGFLS------------------------------------------------------------------------------------VRTEFIGQP--------------------------ERVKELF-------LKG------------------------------------------------------------------------------------------------A-------VDLGREPSFQGHGLLDLMKVL--------- 265
 266 ----------------------------------------------------------------------------------------V--RV--------------A--------------------VLD---------------------------T--------------GVLP-F------H-------------K---------A--------------------------------FADKSVADKSVADKSVADKIVAMKNFVP-----------------------NEDNDLYY-DVH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIVL-------------------------------------------------------------------------------QT--APF-V--RLVIC---KV---LDSQ----------G-RG--Q------------PKW-------------------------------------A--------ADA--------------VDWLLG--VEN-----CPV-------------------------------------------------DI-----------------------------------------ISMSLGSDSYDSEMRRAVSEAV-------------A-----------------------------------------------------------R----GK-----V--------------------------------------------------------------------------------------V---------------VAAAS-NDGRK------GMTNIGF-------------------------------------------------------------------------------------------------------------------------------------------------------PA----------RLGD-------------------V---IC---VG--S------------------------------H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSYGYYQPSSFS--------STGRE--------L---------------------------------------------------------------D-----F------L-----------------A-----P-------------G-----------------EQ--------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAPD--SRTI-NFYRRMSG------TSQATPIIA----G---------------------------I------------------AAMV----IS------------YAETVG----------------------------------------------------------------------------------G------------------KAMRNAV-------SNTT------------------------------------------------------------------------------------------------------------------------------------- 266
 267 ----------------------------------------------------------------------------------------V--TV--------------A--------------------VLD---------------------------T--------------GILS-C------H-------------K---------D--------------------------------F---------------AGKIVAMKNFVP-----------------------NEDNDFYYNDYN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIML-------------------------------------------------------------------------------QT--APF-A--RLVIC---KV---LSSF----------GQTN--Q------------SKW-------------------------------------I--------ADA--------------IDWLLN--DEEGPKTFCPV-------------------------------------------------DI-----------------------------------------ISMSLGGGLFNSDLKRAVSEAG-------------A-----------------------------------------------------------Q----GK-----V--------------------------------------------------------------------------------------V---------------LAAAT-NDGRK------GMTNIAF-------------------------------------------------------------------------------------------------------------------------------------------------------PA----------RFGD-------------------V---IC---VG--S------------------------------H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRFG--QPSLFS--------SVGRE--------L---------------------------------------------------------------D-----F------L-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAPS--SR---GNYQRMSG------TSQATPTVA----G---------------------------I------------------TAIV----IS------------YAETVG----------------------------------------------------------------------------------G------------------QMMRAAV-------SNTT------------------------------------------------------------------------------------------------------------------------------------- 267
 268 ----------------------------------------------------------------------------------------V--TV--------------A--------------------VLD---------------------------T--------------GILA-C------H-------------N---------E--------------------------------F---------------LNKIVAVKNFVP-----------------------NEAGDLCY-DYN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TG-C-----------------------AGILL-------------------------------------------------------------------------------RT--APF-V--RLVVC---KV---MSGQ----------G-NG--Q------------LKW-------------------------------------A--------ADA--------------IDWLLN--DETGPKNYCPI-------------------------------------------------DI-----------------------------------------ISMSFGCASFDSDLRRAVSEAV-------------G-----------------------------------------------------------R----GK-----V--------------------------------------------------------------------------------------V---------------VAAAS-NDGRK------KLTNIAF-------------------------------------------------------------------------------------------------------------------------------------------------------PA----------RFGD-------------------V---IC---VG--S------------------------------C-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNLG--QPSSFT--------PTGRE--------I---------------------------------------------------------------D-----F------L-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PAPS--SSYLDDQLR--SG------TSEATPMVA----G---------------------------I------------------AAMV----IS------------YAETVG----------------------------------------------------------------------------------G------------------RPVRTTV-------CHT-------------------------------------------------------------------------------------------------------------------------------------- 268
 269 ----------------------------------------------------------------------------------------I--VI--------------G--------------------ILD---------------------------S--------------GLKV-D------H-------------L---------A--------------------------------F---------------RGRILASKNF--VHD-NLP-ASSTDEDE-AMECQHDEGYDLTI-DRH---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-C-----------------------ASIAA----GDKFD-------------------------------------------------FRAPDGTP----NTRETTWRMGV--APF-A--KIIYG---KV---ASSD----------G-NT--N------------PKF-------------------------------------L--------TEA--------------IKWLLEFPDDSDRK----V-------------------------------------------------DI-----------------------------------------ISLSLGFQIFDAELRKVISEAN-------------S-----------------------------------------------------------K----GK-----I--------------------------------------------------------------------------------------I---------------ICAAS-NDGRQ------QQTNIAF-------------------------------------------------------------------------------------------------------------------------------------------------------PA----------RFGD-------------------V---IC---VG--S------------------------------H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRNG--QPSASS--------PTGRE--------I---------------------------------------------------------------D-----F------L-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WGAS--SAHE-DAVIAMSG------TSVATPFVA----G---------------------------I------------------AAIV----IK------------AAHHIG----------------------------------------------------------------------------------G------------------DPLRKKV-------SNTT------------------------------------------------------------------------------------------------------------------------------------- 269
 270 ----------------------------------------------------------------------------------------I--VI--------------G--------------------ILD---------------------------S--------------GLCV-G------H-------------Q---------A--------------------------------F---------------AGSTLGLGNFVPVHGVQGP-VSPTAGDEQPMEWEADDENDPD--DRY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TL-C-----------------------ASIAL----GRPFK-------------------------------------------------VRPPDDAPFLQQTGQEEPWLTGV--APF-A--KIVAG---RV---ADCE----------G-RT--H------------PGW-------------------------------------V--------ANG--------------IRWILSL-DGTDKQ----V-------------------------------------------------DI-----------------------------------------ISLSLGFNTFHAGLREAIFEAN-------------R-----------------------------------------------------------R----GK-----I--------------------------------------------------------------------------------------I---------------VCAAS-NDGRQ------QQTNIAF-------------------------------------------------------------------------------------------------------------------------------------------------------PA----------RFGD-------------------V---IC---VG--S------------------------------H-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRLG--QPSAFT--------PTGRE--------I---------------------------------------------------------------D-----F------M-----------------A-----P-------------G-----------------ED--------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WGAS--SANV-NAAKPFTG------TSVATPFVA----G---------------------------I------------------AAIV----LK------------AAHHIG----------------------------------------------------------------------------------G------------------HELRQKV-------SNTT------------------------------------------------------------------------------------------------------------------------------------- 270
 271 --------------------------------------TGVDKLH-------ARG-ILGQ--------------------------G-I--KI--------------A--------------------VLD---------------------------T--------------GIDY-T------H-------------P---------F--------------------------------LGG--------------GIGPGK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--I-----------------------------------------------------------------------------------IGGFD---FVGDDYDGTNLPHPDEDPLDQCQ--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----TDGGN-------------------------------EY------------NFT----------------------GV--APE-A--EQFAY---RI---FGCE----------G-FT--Q------------DDV-------------------------------------I--------IAA--------------L-----------FR---GV--------------------D-----D------G----------A----DI-----------------------------------------LSLSLG---------------G--------------------AH--------------------------GWTVSAGAVVASR---------IAET----GK-----I--------------------------------------------------------------------------------------I---------------TIAAG-ND--------GS---------R-----GSWYAAS---------------------------------------------------------------------------------------------------------------------------------------P-SSAI-N---------------------------A---IS---VG--S------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENVVIPLQTAKLHNVEQSSVIYFQLKPLPIEGEWPVYVISNAVGNYTTALIRAEDGEYIVEKYFAGEDVKVSFPQNGGTVSFPNP-RG-------G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LM-STF-----S--T--------Y-GPT-N----------------------------------------------------------------------D-----FYFKPAIS-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-AYP---------------------------------------------------------------------------------------------------------------------TTLGSF-AV----------------LSG------TSMATPFAA----G---------------------------A------------------AALL----LQVQG---KNAE----VARA----------------------------------------------------------------------------------A---------------------RDIF-------QTT-----------------------------------------------------------------------------------------------------AMTIRSKNEEDALIETVTQTGSGLIN------- 271
 272 --------------------------------------TGVDKLH-------AQG-ITGA--------------------------G-I--KI--------------G--------------------ILD---------------------------T--------------GIDY-T------H-------------P---------T--------------------------------LGG--------------AFGPGN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K--V-----------------------------------------------------------------------------------IGGFD---LVGDDYDGTNTPVPDPDPLDQCA--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----ANPDN-------------------------------AF------------NIS----------------------GV--AFQ-A--SLSAY---RV---FGCV----------G-FV--T------------DDV-------------------------------------L--------VDA--------------L-----------LL---GF--------------------N-----E------G----------Q----DI-----------------------------------------LTLSLG---------------G--------------------AD--------------------------GWTESVSAVVASR---------IAAT----GK-----V--------------------------------------------------------------------------------------V---------------TIAAG-ND--------GA---------S-----GAWYTSS---------------------------------------------------------------------------------------------------------------------------------------P-GNGI-D---------------------------V---IS---VA--S------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNTVVPLQTAQVHGVTHDPIIYQDTFPLPINDTRPI---------------------------ASGQNVSLSFPQSGGLIQFPDP-AG-------G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LI-SSF-----T--S--------Y-GPS-N----------------------------------------------------------------------D-----FFFKPAVA-----------------A-----P-------------G-----------------GN--------------------------------I------------------------------------------------------------------LS-TLP---------------------------------------------------------------------------------------------------------------------VNLGLF-GI----------------ESG------TSMATPFVA----G---------------------------S------------------AALL----FQAKG---TSAA----VGRS----------------------------------------------------------------------------------A---------------------RTLF-------ETT-----------------------------------------------------------------------------------------------------AQRVPSTHTDGDPLQT----------------- 272
 273 IAMESAW----------------------------------------------DG-SKGE---------------------------GV--TV--------------A--------------------VID---------------------------T--------------GVTR-V------P-------------D---------L--------------------------------R---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTQFVTG---YNFVDDNRDTTDY------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----QATNN-------------------------------EY------------GVA----------------------GI--APK-A--KIMPL---KV---LGDN----------G-GG--T------------VAD-------------------------------------I--------AEA--------------I-----------IY---AA--------------------D-----N------G----------A----SV-----------------------------------------INMSLG---------GGG---E--------------------SK--------------------------TLAD-----AIDY-A--------YSK----GV-----V--------------------------------------------------------------------------------------I---------------IAAAG-NE--------GQ---------N--------AAAY---------------------------------------------------------------------------------------------------------------------------------------P-G--R-Y----PK---------------------V---IS---VA--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------TG-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-ADY-----S--N--------Y-G---A--------------------GV------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------GS-------------------------TDGKDGKI------------------------------------------------------------------LQ-E----------------------------------------------------------------------------------------------------------TIDPDTREP--------VL-MG----------------FQG------TSMAAPHVA----G---------------------------T------------------AALI----QSVQLQQ-------AKVGLS-----------------------------------------------------------------TRAAENLTIAEVSEPEMV---------------------LKIL-------KAS------------------------ARS------------------------------------------------------------------------VPNDSLN------YYGAGHVNAGEAV--------- 273
 274 IGIEGAW----------------------------------------------SQ-TKGS---------------------------GI--TV--------------A--------------------VID---------------------------T--------------GITK-V------R-------------D---------L--------------------------------Y---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ETKFVKG---YDFVNDREEAKDD------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----QATNN-------------------------------KY------------GVA----------------------GI--AYE-A--SLMPL---KV---LSSY----------G-GG--T------------VAD-------------------------------------I--------AEA--------------I-----------KF---AA--------------------D-----K------G----------A----DV-----------------------------------------INMSLG---------GSG---E--------------------SK--------------------------LMKE-----AIEY-A--------HRK----GV-----V--------------------------------------------------------------------------------------I---------------IAAAG-NE--------NT---------N--------GASY---------------------------------------------------------------------------------------------------------------------------------------P-A--R-Y----PY---------------------V---IG---VS--A------------------------------I-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------DG-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-APY-----S--N--------F-G---A--------------------GV------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------GS----------------------------EAGKI------------------------------------------------------------------LQ-E----------------------------------------------------------------------------------------------------------TID-ENGEG--------VF-LG----------------FQG------TSMASPHVA----G---------------------------V------------------AALI----RA--------------------------------------------------------------------------------------------AGIKEPDEV---------------------LKVL-------KQS------------------------ARV------------------------------------------------------------------------IQDDGLN------YYGAGQLNAEAAVR-------- 274
 275 -------------------------------------------------------------VQAVSAW-----NITRGA--------GV--KV--------------A--------------------IID---------------------------T--------------GVAY-E------NYTDPVTGTQYALAP---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANTK-------------------------------------F----------------------------------D-------T--ANAYDFVN--------------------NDTHANDDNG--------------------------------------------------------------------------------------------------------------------------------------------HG-------TH-V-----------------------CGTIA----QSTNN-------------------------------SI------------GCA----------------------GI--AYE-A--TILPI---KV---LDSS----------G-SG--T------------YDA-------------------------------------I--------ANG--------------I-----------IW---AA---------------------------------D----------HGA--RV-----------------------------------------INMSLG-GSQGSTT---------------------------LYN-----------------------------------AIKY---------AYNK----GV-----V--------------------------------------------------------------------------------------I---------------VCAAG-ND--------GRPLVSY--------------------------------------------------------------------------------------------------------------------------------------------------------PAAYTE-----------------------------C---IA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RFDGRR-AKY-----S--N--------Y-GSA-L----------------------------------------------------------------------D-----I------V-----------------A-----PGGDTSVDQNKDGYG-----------------DG--------------------------------I------------------------------------------------------------------LQQTFS-----------------------------------------------------------------------------------------GSPTNFG--------------------------Y-YF----------------FQG------TSMATPH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 275
 276 -------------------------------------LKNGSRPGCDVGCMEAWKKCTGD--------------------------PSI--IV--------------A--------------------VLD---------------------------E--------------GVMY-T------H-------------P---------DLKGNMWINEKEELYADKDADGNGYKDDKYGYNFVSNSGIISWMDAVDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AMNNN--------------------------------------------------------------GEGVCGIAGGDGSKN-SGVKIMSC---QV---------------FAGEAGVTL------------DAE----------------------------------------------ARA--------------I-----------KY--------------------------------------A----------ADNGAVI-----------------------------------------LQCSWGYNSSLANL----------------------------IEGYTPGPGSEEEWEKLYPLEKDALDYFINNAGSPNGVIDG-----------------GL-----A--------------------------------------------------------------------------------------I----------------FASG-NE----------------------------------------------------------------------------------------------------------------------------------------------------------------YAGMAAFPAAYSK-----------------------------C---IS---VSAVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADFTPASYS--N--------Y-GKEVT----------------------------------------------------------------------------I------S-----------------A-----P-------------GGDTEYYNPVGQDDPEGWEE--------------------------GIHSGSI------------------------------------------------------------------LS--------------------------------------------------------------------------------------------------------------------------------------TWIQNGNATYGFMDG------TSMACPHVS----G---------------------------V------------------AALGLSYAVK------------QRRHFK----------------------------------------------------------------------------------A------------------SEFVELL-------KSSTKPLDSWYNTGEVKAYY--------------------------------------------------------------------------------------------------------------------- 276
 277 -----------------------------------------------------WQKCKGD--------------------------PSI--IV--------------A--------------------VLD---------------------------E--------------GVMN-T------H-------------P---------DLVGNIWINEGEELYADDDADGNGYKDDKYGYNFVSNTGVISWMETSDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----AMNNN--------------------------------------------------------------GIGVCGIAGGDGTKN-SGVKIMSC---QV---------------FSGDYGVSL------------DAE----------------------------------------------ARA--------------I-----------KY--------------------------------------A----------ADNGAVI-----------------------------------------LQCSWGYNSSLANM----------------------------IEGYTPGPGTEKEWESIYPLEKEALDYFINNAGSPNGVIDG-----------------GL-----A--------------------------------------------------------------------------------------I----------------FASG-NE----------------------------------------------------------------------------------------------------------------------------------------------------------------YAGMPAFPAAYSK-----------------------------C---IA---VSAVA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADFTPASYT--N--------Y-GVEAT----------------------------------------------------------------------------V------S-----------------A-----P-------------GGDTEYYNPVGKEDPEAWAE--------------------------GIYSGSI------------------------------------------------------------------LS--------------------------------------------------------------------------------------------------------------------------------------TWIQNGTATYGFMDG------TSMACPHVS----G---------------------------V------------------AALGLSYAVK------------QRRHFK----------------------------------------------------------------------------------A------------------TEFIELL-------KNSAKPLDGWYTGGKVKTYYRNHLSAGASPTKVELSKYVGKMGTGLVNAG--------------------------------------------------------------------------------------- 277
 278 -YQQYQWHLHNATGGINA-----------------------PSAW-------DVS--QGE--------------------------G-V--VV--------------A--------------------VLD---------------------------T--------------GILP-Q------H-------------P---------D--------------------------------L---------------------V----------------GNLLE--GYDFISDAETSRRATND------------------------------RVP----------------------------------------------------------------------------------------------------------------------------------GAQDYGDWVENDNE------CYTGSV------------AE-----------------------------------------------------------------------------------------D---S---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------TH-V-----------------------AGTVA----EQT-N-------------------------------NG------------VGM--A-------------------GV--AHK-A--KVLPV---RV---LGKC----------G--G--Y------------LSD-------------------------------------I--------ADA--------------I-----------TW---AS----------GGTVAGVPANA-----N------P----------A----EV-----------------------------------------INMSLG---------GSG-SCD---------------------G--------------------------TYQD-----AING-A--------ISR----GT-----T--------------------------------------------------------------------------------------V---------------VVAAG-NE--------TD---------N----A---SKYR---------------------------------------------------------------------------------------------------------------------------------------P-A--S-C----DG---------------------V---VT---VG--A------------------------------T-----------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------TG-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-TYY-----S--N--------Y-G---S--------------------RV------------------------------------------------D-----L------S-----------------G-----P-------------G-----------------GG----------------------GSVDGNPGGYV------------------------------------------------------------------WQ-SGS-----------------------------------------------------------------------------------------------DAATTPESGS-------Y--------SY-MG----------------MGG------TSMASPHVA----A---------------------------V------------------AALV----QS----A-------LIAKGK-------------------------------------------------------------DPLAPAA--------------M---------------------RTLL-------KET----------------------------------------------------------------------------------------------------------ARPFP--VSIPTATPIGTGIVDAKAAL- 278
 279 RYND-QWHYYEAAAGINA-----------------------PAAW-------DKA--TGQ--------------------------G-V--VV--------------A--------------------VLD---------------------------T--------------GYRP--------H-------------L---------D--------------------------------L---------------------D----------------ANILP--GYDMISNTFVANDG-GA------------------------------RDN----------------------------------------------------------------------------------------------------------------------------------DARDPGDAVTRGECGTDSSGQPVPRA------------DQ-----------------------------------------------------------------------------------------D---S---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------TH-V-----------------------AGTVA----AVT-N-------------------------------NG------------EGV--A-------------------GV--AYD-A--KVVPV---RV---LGKC----------G--G--L------------TSD-------------------------------------I--------ADG--------------I-----------IW---AS----------GGS-DRVPANA-----N------P----------A----VV-----------------------------------------INMSLG---------GGG-ACS---------------------A--------------------------TTQN-----AINQ-A--------RNN----GT-----V--------------------------------------------------------------------------------------I---------------VIAAG-ND--------ND---------N----S---ANYN---------------------------------------------------------------------------------------------------------------------------------------P-G--N-C----NG---------------------V---VN---VA--S------------------------------V-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------DG-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYY-----S--N--------Y-G---A--------------------NI------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------GA----------------------QSFADDPEG-I------------------------------------------------------------------LS-THN-----------------------------------------------------------------------------------------------SGSGAP--SN-------D--------SY-HY----------------SQG------TSMAAPHVA----G---------------------------V------------------AALI----KQ----A------------K-------------------------------------------------------------PSATPDE--------------V---------------------ETIL-------KNT----------------------------------------------------------------------------------------------------------TRSFA--GSCSN---CGTGVVDAAAAVN 279
 280 HYRE-QWHYFDRY-GVKA-----------------------DKVW-------DMG-FTGQ--------------------------N-V--VV--------------A--------------------VVD---------------------------T--------------GILH--------H-------------R---------D--------------------------------L---------------------N----------------ANVLP--GYDFISNSQISLDG-DG------------------------------RDA----------------------------------------------------------------------------------------------------------------------------------DPFDEGDWFDNWACGGYPDPRK---E------------RS-----------------------------------------------------------------------------------------D---S---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------SH-V-----------------------AGTIA----AVT-N-------------------------------NR------------IGV--A-------------------GV--AYG-A--KVVPV---RA---LGRC----------G--G--Y------------DSD-------------------------------------I--------SDG--------------L-----------YW---AA----------GGRIAGIPENR-----N------P----------A----KV-----------------------------------------INMSLG---------SDG-QCS---------------------Y--------------------------NAQT-----MIDR-A--------TRL----GA-----L--------------------------------------------------------------------------------------V---------------VVAAG-NE--------NQ---------N----A---SNTW---------------------------------------------------------------------------------------------------------------------------------------P-T--S-C----NN---------------------V---LT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------RG-------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---V--------------------DV------------------------------------------------D-----L------A-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------LS-TVD-----------------------------------------------------------------------------------------------SGTRRP--VS-------D--------AY-SF----------------MAG------TSMATPHVS----G---------------------------V------------------AALV----IS----A-------ANSV-N-------------------------------------------------------------KNLTPAE--------------L---------------------KDVL-------VST----------------------------------------------------------------------------------------------------------TSPFN--GRLDRA--LGSGIVDAEAAVN 280
 281 SYRQ-QWHYFGNY-GVKA-----------------------NKVW-------DRG-FTGQ--------------------------G-V--VV--------------S--------------------VVD---------------------------T--------------GILD--------H-------------V---------D--------------------------------L---------------------N----------------GNMLP--GYDFISSAPNARDG-DQ------------------------------RDN----------------------------------------------------------------------------------------------------------------------------------NPADEGDWFDNWDCGGYPDPRR---E------------KK-----------------------------------------------------------------------------------------F---S---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------SH-V-----------------------AGTIA----AVT-N-------------------------------NG------------VGV--A-------------------GV--AYG-A--KVIPV---RV---LGKC----------G--G--Y------------DSD-------------------------------------I--------TDG--------------M-----------YW---SA----------GGHIDGVPDNQ-----N------P----------A----QV-----------------------------------------VNMSLG---------GGG-GCS---------------------Q--------------------------NSQR-----MIDK-T--------TNL----GA-----L--------------------------------------------------------------------------------------I---------------VIAAG-NE--------NQ---------D----A---SRTW---------------------------------------------------------------------------------------------------------------------------------------P-S--S-C----NN---------------------V---LS---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------KG-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-APF-----S--N--------Y-G---A--------------------RV------------------------------------------------H-----L------A-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------LS-TID-----------------------------------------------------------------------------------------------VGQAGP--VR-------S--------SY-GM----------------KAG------TSMAAPHVS----G---------------------------V------------------AALV----IS----A-------ANSI-G-------------------------------------------------------------KTLTPSE--------------L---------------------SDIL-------VRT----------------------------------------------------------------------------------------------------------TSRFN--GRLDRG--LGSGIVDANAAVN 281
 282 FYND-QWHYYSEY-GVKA-----------------------DKVW-------DRG-ITGK--------------------------G-V--TV--------------A--------------------VVD---------------------------T--------------GIVN--------H-------------P---------D--------------------------------L---------------------N----------------ANVIPGSGYDFIQEAEIAQDG-DG------------------------------RDS----------------------------------------------------------------------------------------------------------------------------------NPADAGDWHSNWACGKYPDPRY---E------------KR-----------------------------------------------------------------------------------------N---S---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------SH-V-----------------------AGTIA----AVT-N-------------------------------NR------------IGV--S-------------------GV--AYD-A--KIVPV---RV---LGRC----------G--G--Y------------NSD-------------------------------------I--------NEG--------------M-----------YW---AA----------GGHIDGVPDNK-----H------P----------A----QV-----------------------------------------INMSLG---------GPG-VCG---------------------S--------------------------TEQT-----LINR-A--------TQL----GA-----T--------------------------------------------------------------------------------------I---------------IVAAG-ND--------NI---------D----A---YGVT---------------------------------------------------------------------------------------------------------------------------------------P-A--S-C----DN---------------------I---LT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NG-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------H-G---S--------------------VV------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------AG--------------------------------I------------------------------------------------------------------TS-TVD-----------------------------------------------------------------------------------------------SGARYP--SG-------P--------SY-SL----------------MDG------TSMATPHVA----G---------------------------V------------------AALV----IS----A-------ANSV-N-------------------------------------------------------------KEMTPAQ--------------V---------------------RDVL-------VRT----------------------------------------------------------------------------------------------------------VSSFN--GTPDRR--IGAGIVDADAAVN 282
 283 RYSE-QWGYFNPTAGANL-----------------------PKAW-------DRT--TGS--------------------------ARV--VV--------------A--------------------VID---------------------------T--------------GYRP--------H-------------A---------D--------------------------------L---------------------A----------------ANLLP--GYDFISDIPSANDG-NG------------------------------RDS----------------------------------------------------------------------------------------------------------------------------------DASDPGDWVSAQEDG-DPSGPFYGCG------------AS-----------------------------------------------------------------------------------------D---S---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------WHG-------TH-V-----------------------AGTIG----AVT-N-------------------------------NG------------VGV--A-------------------GI--SWV-G--KVLPV---RV---LGKC----------G--G--M------------LSD-------------------------------------I--------ADG--------------M-----------RW---AA----------GLPVPGAPSNP-----N------P----------A----RV-----------------------------------------LNLSLG---------GYGRTCS---------------------S--------------------------TYQN-----AINE-I--------TSR----GA-----N--------------------------------------------------------------------------------------V---------------VVAAG-NN--------GG---------S----V---STTQ---------------------------------------------------------------------------------------------------------------------------------------P-A--N-C----RG---------------------V---IA---VG--A------------------------------I-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------RG-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------T-G---A--------------------AV------------------------------------------------K-----I------S-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------LS-TLN-----------------------------------------------------------------------------------------------AGKTSP--GA-------D--------SY-AS----------------YSG------TSMATPHVA----G---------------------------T------------------VALM----LA----V------------N-------------------------------------------------------------STLSPSQ--------------I---------------------LQRL-------QSS----------------------------------------------------------------------------------------------------------ARPFSSGSSCSTST-CGAGLLDAGNAVD 283
 284 LDLEYAEPDWRVYPAVIPNDSYYQHEQWNLHSPNISNYGIDMPGA-------WAI-TTGS--------------------------AEI--TV--------------A--------------------VID---------------------------T--------------GI-V-S------H-------------E---------D--------------------------------IED--------------N-----RILPGLNLQNKL-LAPI---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D----------------PDGGDV-------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TH-V-----------------------TGIIA----AQSDN-------------------------------GI-------------------------------------GI--AGIDWNAQILPV---RAI-----G---------------------------------------------------------------------FNFGSITTLSEG--------------I-----------RW---AA--------------GDDSVYNSTVNLN------V----------A----NV-----------------------------------------INLSVQ-----TDG-DRECSST-------------L------QD-----------------------------------AINF---------AVAN----DI-----I--------------------------------------------------------------------------------------V---------------VAAAG-NF--------NL---------------DSTGTS----------------------------------------------------------------------------------------------------------------------------------------P-ANCKNV-------------------------------IS---VG--A------------------------------TTY------------------------DGNR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----S--N--------Y-GNM-V----------------------------------------------------------------------T-----L------S-----------------A-----P-------------G-----------------GA--------------------------IVGNYKI------------------------------------------------------------------LS-TMS-----------------------------------------------------------------------------------------------------------------------NNNY-GY----------------LSG------TSMAAPHVA----G---------------------------V------------------ISLM----LA------------ANPLLS-----------------------------------------------------------------QED--------------I----------------------ELI-------LIG--------------------------------------------------------------------------------------------------SATLFPADSDCHSKGCGAGILNA------------- 284
 285 --------------------------------------KISAALA-------WDI-NKGD--------------------------TNV--VI--------------G--------------------IVD---------------------------T--------------GVDW-D------H-------------P---------D--------------------------------LAA--------------NIYTNWNEIPNNGIDDDN-NGYV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D---DIRGWDFGGLSGTPDNNPMEDQP--------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TH-V-----------------------AGISS----AVTDN-------------------------------GI-------------------------------------GV--ASIGFKCKLMPV---KTTRNDQRG---------------------------------------------------------------------SNGPYIIFGYEG--------------I-----------VY---AA--------------D-----------N------G----------A----KV-----------------------------------------INCSWG-----GSG----FSMF-------------G------QE-----------------------------------TINY---------ALSQ----GS-----L--------------------------------------------------------------------------------------V---------------VAAAG-NS--------N-----------------SSGSHY---------------------------------------------------------------------------------------------------------------------------------------P-SSYKGV-------------------------------LS---VA--S------------------------------TTS------------------------TDTK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSF-----S--N--------F-GYS-V----------------------------------------------------------------------D-----V------S-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------YN-TWQ-----------------------------------------------------------------------------------------------------------------------NDTY-AT----------------LSG------TSMASPLTA----G---------------------------L------------------AALV----FS------------QFPSYN-----------------------------------------------------------------AEQ--------------V---------------------GEQI-------RVN--------------------------------------------------------------------------------------------------SDNIDNLNPSFQYQ-LGFGRINA------------- 285
 286 --------------------------WDQQWAPRAIKAQSAWAAG-------VTG---KC----------------------------V--RV--------------A--------------------VLD---------------------------T--------------GMWW-D------H-------------P---------D--------------------------------LAG--------------RVDVDY-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ARSF-------------------------------------VDGIPPYA---------------------------------------DSQNYF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------WHA-------SH-V-----------------------AGIVA----GSANN-------------------------------GG------------IV-----------------------GI--APE-A--TIIPI---KV---L-DN----------N-AG--D------------NSF-------------------------------------L--------IQG--------------L-----------LY---AA--------------------S-----PLGPDGAG----------A----DI-----------------------------------------INLSLGGFGNPN------------------------------DK--------------------------NDTWALYNKVLNY---------VASQ----GV-----L--------------------------------------------------------------------------------------V---------------VAAAG-NDALN--LGRT-----------------------RNTFVS---------------------------------------------------------------------------------------------------------------------------------P-CENGGN---------------------------T---VC---VS--S------------------------------TGPLDVCKTCQDDWINTCLESPSTWDLKQQL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALY-----S--N--------Y-GP-------------------------------------------------------------------------SAIS--V------A-----------------G-----P-------------G-----------------GDYRSAFEWYAKWYDPATDSFLPGTPPTCWFVDQV------------------------------------------------------------------LS-VGA---------------------------------------------------------------------------------------------------------PNRPDL---------PAF-IQ----------------YTG------TSQAAPAVS----G---------------------------V------------------AALM----I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 286
 287 VNADSAW---------------------------------------------DTT-LGSS--------------------------S-V--KI--------------A--------------------VVD---------------------------Q--------------GVKY-D------H-------------P---------D--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSQFGSNKGRDFVDNDGD---PYPDL------------LS-----------------------------------------------------------------------------------------D---E------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TH-V-----------------------AGIAA----GTTDN-------------------------------NE-------------------------------------GIGGISN-S--TLLSG---RA---LSES----------G-SG--S------------TSD-------------------------------------I--------ADA--------------I-----------EW---A--------------------AD-----Q------G----------A----DV-----------------------------------------INLSLG-------V-GGY---S---------------------S--------------------------TMKN-----AVSY-A--------TQQ----GS-----L--------------------------------------------------------------------------------------V---------------VAAAG-ND--------GR---------------Q--SVSY---------------------------------------------------------------------------------------------------------------------------------------P-A--A-Y----SE---------------------C---VA---VS--A------------------------------L-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------DE-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-ASY-----S--N--------Y-G------------------------------------S---E--------------------I------------D-----L------A-----------------A-----P-------------G-----------------TN--------------------------------V------------------------------------------------------------------LS-CWT----------------------------------------------------------------------------------------------------------TST------------EY-NE----------------ISG------TSMATPVVS----G----------------------------------------------VA-G----LA----L-------AVHNLS-----------------------------------------------------------------PAG--------------L---------------------RNHL-------KNT-------------------------AV------------------------------------------------------------------------DIGLSSTKQGSGRVDAANAVT-------------- 287
 288 ---------------------------LQELIPYGISMIQANQL----------S-IGSS--------------------------P-V--TV--------------C--------------------IVD---------------------------T--------------GVD-IT------H-------------P---------D--------------------------------LDADNADGANRFSQVDGSVMNW---------YD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DSR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-A-----------------------AGIVA----ARI------------------------------------------------------------ENNL--------GIRGVGE-I--PLFVT---RG---LNDD----------G-RA--Y------------ESD-------------------------------------I--------IQA--------------I-----------EQ--CKL--------------------------------------------AGA--KV-----------------------------------------VSLSLGGLAATSRT-RSLYSRL-------------DE------Q--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------V---------------FAAAG-NE--------GSPLSIF--------------------------------------------------------------------------------------------------------------------------------------------------------PA--ALPE---------------------------V---VS---VAAVQ------------------------------E--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-YWNS-----S--N--------Y-GPY-I----------------------------------------------------------------------E-----L------S-----------------A-----P-------------G-----------------RR--------------------------------V------------------------------------------------------------------LSTVPPD---RYAT--------------------------------------------------------------------------------------------------------------------------------------YSG------TSMATPFAA----G----------------------------------------------AAAL----VWS----HFPS-------CS-----------------------------------------------------------------HKQ--------------I---------------------RFAM-------AYT-------------------------------------------------------------------------------------ADKKDST---------------QGCSERYGHGIVQVKAAYD-------- 288
 289 -------------------------------------LQKSTVAT-------KSP-VSRTDIRVTEAW-----KRSNGGR-------GV--VV--------------A--------------------VID---------------------------S--------------LIQW-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGSL-------------------------------------YTVKAADK-------------------------CPDEVHGWDFSSGGNSLDPCEIGDGDTRISRTELAILTAKFQDTFKLSDAEL----------------------------------------------------------------------IRQYSVEALEMKQKYPNASFEEIAQILRYVFRTYKVGAE-----------------------------FHG-------TW-V-----------------------SGIIA----AKPQD-------------------------------NQ------------GLV----------------------GV--APN-A--QILPV---RL---FGLN----------G-SY--S------------PSA-------------------------------------Y--------IEA--------------I-----------GY---AA---------------------------------D----------RGA--DI-----------------------------------------INLSLG-STLPTDG---------------------------EEE-----------------------------------AIAD---------VLKA--HPKL-----V--------------------------------------------------------------------------------------I---------------VAAAG-NE--------NSNRVAY--------------------------------------------------------------------------------------------------------------------------------------------------------PAAYPG-----------------------------V---VA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLLGNR-APY-----S--N--------Y-GKG-L----------------------------------------------------------------------A-----I------V-----------------A-----PG------------G-----------------DL--------------------------------N------------------------------------------------------------------TPGMLG-----------------------------------------------------------------------------------------GIPTTGGTWLDAFWQGMSAPESRWSTVLDARGKY-WW----------------VEG------TSFASPAVA----G---------------------------V------------------VALMKGENKEISRQS-----------------------------------------------------------------------------------------------L---------------------VSIL-------KST------------------------------------------------------------------------------ASYQGLAISDDDARRYRSQRRKGEVSSAVKGQPYFFGKGLVNANAAVKAVKEKR-- 289
 290 -----------------------------------------------------------N--------------------------D-T--LI--------------A--------------------VVD---------------------------T--------------GVDS-T------L-------------S---------D--------------------------------L---------------------E----------------G-----------------------------------------------------KVR---------------------------------------------------------------------------------------------------------------------------TDL--------------------GRNFVGRNNN------------AM-----------------------------------------------------------------------------------------D---D---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----AES-G-------------------------------NG------------YSMA---------------------GL--HAK-A--NIIPV---KV---LDST----------G-AG--D------------TEQ-------------------------------------I--------ALG--------------I-----------KY---AA--------------------D-----K------G----------A----KV-----------------------------------------INLSLG---------GGY---S---------------------R--------------------------VLEF-----ALKY-A--------ASK----NV-----T--------------------------------------------------------------------------------------I---------------AAASG-ND--------GE--------------S---ELSY---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----KY---------------------V---MS---VG--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------MD-------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-ADF-----S--N--------Y-G---K--------------------GL------------------------------------------------D-----I------T-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------PS-LVP---------------------------------------------------------------------------------------------------------------NG--------NV-TY----------------MSG------TSMATPYAA----A---------------------------A------------------AG-L----LL----S-------QNPKLK-----------------------------------------------------------------PNE--------------V---------------------EDIL-------KRT-------------------------AD------------------------------------------------------------------------DISFDSVDGGEEELYDENGDPIEIPH--------- 290
 291 -----------------------------------------------------------N--------------------------D-T--LI--------------A--------------------VVD---------------------------T--------------GVDS-T------L-------------A---------D--------------------------------L---------------------K----------------G-----------------------------------------------------KVR---------------------------------------------------------------------------------------------------------------------------TDL--------------------GHNFVGRNNN------------AM-----------------------------------------------------------------------------------------D---D---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----AQS-D-------------------------------NG------------YSMT---------------------GL--NAK-A--KIIPV---KV---LDSA----------G-SG--D------------TEQ-------------------------------------I--------ALG--------------I-----------KY---AA--------------------D-----K------G----------A----KV-----------------------------------------INLSLG---------GGY---S---------------------R--------------------------VLEF-----ALKY-A--------ADK----NV-----L--------------------------------------------------------------------------------------I---------------AAASG-ND--------GE--------------N---ALSY---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----KY---------------------V---MS---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------MD-------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-ADF-----S--N--------Y-G---K--------------------GL------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------PS-LVP---------------------------------------------------------------------------------------------------------------NG--------NV-TY----------------MSG------TSMATPYAA----A---------------------------A------------------AG-L----LF----A-------QNPKLK-----------------------------------------------------------------RTE--------------V---------------------EDML-------KKT-------------------------AD------------------------------------------------------------------------DISFESVDGGEEELYDDYGDPIEIPKTPGVDWHSG 291
 292 ENGGVKN-------ADVKYEPANTLL---------------------------SK-RKLN--------------------------D-T--LI--------------A--------------------VVD---------------------------T--------------GVDS-T------L-------------A---------D--------------------------------L---------------------K----------------G-----------------------------------------------------KVR---------------------------------------------------------------------------------------------------------------------------TDL--------------------GHNFVGRNNN------------AM-----------------------------------------------------------------------------------------D---D---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----AQS-D-------------------------------NG------------YSMT---------------------GL--NAK-A--KIIPV---KV---LDSA----------G-SG--D------------TEQ-------------------------------------I--------ALG--------------I-----------KY---AA--------------------D-----K------G----------A----KV-----------------------------------------INLSLG---------GGY---S---------------------R--------------------------VLEF-----ALKY-A--------ADK----NV-----L--------------------------------------------------------------------------------------I---------------AAASG-ND--------GE--------------N---ALSY---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----KY---------------------V---MS---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------MD-------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-ADF-----S--N--------Y-G---K--------------------GL------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------PS-LVP---------------------------------------------------------------------------------------------------------------NG--------NV-TY----------------MSG------TSMATPYAA----A---------------------------A------------------AG-L----LF----A-------QNPKLK-----------------------------------------------------------------RTE--------------V---------------------EDML-------KKT-------------------------AD------------------------------------------------------------------------DISFESVDGGEEELYDDYGDPIEIPKTPGVDWHSG 292
 293 -----------------------------------------------------------T--------------------------D-T--LI--------------A--------------------VVD---------------------------T--------------GVDS-T------L-------------A---------D--------------------------------L---------------------K----------------G-----------------------------------------------------KVR---------------------------------------------------------------------------------------------------------------------------TDL--------------------GRNFVDRSNS------------AL-----------------------------------------------------------------------------------------D---D---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----AKR-D-------------------------------NG------------YSMA---------------------GL--NSN-A--GIIPV---KV---LDST----------G-SG--D------------TEQ-------------------------------------I--------ALG--------------I-----------KY---AA--------------------D-----K------G----------A----KV-----------------------------------------INLSLG---------GAY---S---------------------R--------------------------VLEY-----ALKY-A--------ASK----NV-----V--------------------------------------------------------------------------------------I---------------AAASG-NE--------AQ--------------N---ELSY---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----KY---------------------V---IS---VG--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------MD-------M-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-SDF-----S--N--------Y-G---K--------------------GL------------------------------------------------D-----L------T-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------PS-LVP---------------------------------------------------------------------------------------------------------------NG--------NV-TY----------------MSG------TSMAAPHVA----A---------------------------A------------------AG-L----VL----S-------QNPKLK-----------------------------------------------------------------PNE--------------V---------------------EAKL-------KQT-------------------------AD------------------------------------------------------------------------DISFKSEDGKEE----------------------- 293
 294 ---------------------------------------------------------TLQ--------------------------D-T--LI--------------A--------------------VVD---------------------------T--------------GVDS-T------L-------------A---------D--------------------------------L---------------------K----------------G-----------------------------------------------------KVR---------------------------------------------------------------------------------------------------------------------------TDL--------------------GKNFVGRNDN------------AL-----------------------------------------------------------------------------------------D---D---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGIIA----AQQ-D-------------------------------NG------------YSMA---------------------GL--NAH-A--QIIPV---KV---LDST----------G-MG--D------------TEQ-------------------------------------I--------ALG--------------I-----------KY---AV--------------------D-----Q------G----------A----KV-----------------------------------------INLSLG---------GGY---S---------------------R--------------------------VLEY-----ALNY-A--------ASH----GV-----T--------------------------------------------------------------------------------------V---------------AAASG-NE--------AA--------------P---EVGY---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----RY---------------------A---IS---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------LD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-SEF-----S--N--------Y-G---E--------------------GL------------------------------------------------D-----L------A-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------PS-LVP---------------------------------------------------------------------------------------------------------------NG--------NV-TY----------------MSG------TSMATPYVT----A---------------------------A------------------AG-L----LL----S-------QNPSLT-----------------------------------------------------------------PSE--------------V---------------------EKIL-------DET-------------------------AD------------------------------------------------------------------------NITFDSVDGGGEAPTDE------------------ 294
 295 -----------------------------------------------------FT-GIQN--------------------------K-I--KV--------------A--------------------ILD---------------------------N--------------GIYK-E------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGKV-----------------------------------------------------------------------------------VKEFN---TI----------NLNNPII-DET--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-I-----------------------AGIIA----AE-NN-------------------------------NL------------GIL----------------------GV--MPN-I--QLYDV---KV---LDKQ----------G-KG--D------------VDH-------------------------------------L--------IKG--------------I-----------RW---CI--------------------E-----Q------R----------V----NI-----------------------------------------LNISFG---------------L--------------------QS----------------------------ESPELKKAIDE---------AVDS----GI-----I--------------------------------------------------------------------------------------V---------------VAAAG-NT-------------------------YGLGVDY---------------------------------------------------------------------------------------------------------------------------------------P-AKYE-N---------------------------V---IS---IS--S------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------KE-------F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-ASS-----S--A--------K--GK-I----------------------------------------------------------------------D-----F------A-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-TNQ---------------------------------------------------------------------------------------------------------------------V--GGY-ST----------------YSG------TSFATAFAT----G---------------------------V------------------IAAL----LAEGDNTLNL--------DQ----------------------------------------------------------------------------------I---------------------KKIL-------IER-----------------------------------------------------------------------------------------------------SIDLGSTGYDNEFGYGLIQ-------------- 295
 296 ---------------------------------------------------------------------------------------------------------------------------------MD---------------------------S--------------GINK-N------H-------------Q---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGKI-----------------------------------------------------------------------------------VKDYN---AI----------NPGNENV-DNY--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------AGIIA----AH-DD-------------------------------DL------------GLT----------------------GI--SPN-A--EIYDV---KV---LDDK----------G-LA--D------------IDT-------------------------------------L--------IKG--------------I-----------QW---CI--------------------Q-----E------N----------V----KI-----------------------------------------MNISFG---------------V--------------------QS----------------------------DNPKLKEAIDE---------ALDK----EI-----I--------------------------------------------------------------------------------------I---------------VAASG-NT-------------------------LGLSVDY---------------------------------------------------------------------------------------------------------------------------------------P-AKYE-N---------------------------V---IS---VS--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------EN-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-SGV-----S--A--------K--GK-I----------------------------------------------------------------------D-----Y------A-----------------A-----P-------------G-----------------IN--------------------------------I------------------------------------------------------------------LT-TDN---------------------------------------------------------------------------------------------------------------------K--GDY-SY----------------YSG------TSFATAYVT----G---------------------------T------------------VAVL----LAQKDIIFNG--------QN----------------------------------------------------------------------------------I---------------------KTYL-------NDK-----------------------------------------------------------------------------------------------------TKDLGEKGYDSEYGSGLI--------------- 296
 297 --------------------------------QVESWGLRLIGKN-------EKI-EKKS--------------------------N-I--SI--------------A--------------------ILD---------------------------S--------------GIDS-N------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGVV-----------------------------------------------------------------------------------KKEYN---AL----------EPSKGVIEDKF--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------AGIIA----SN-DN-------------------------------KI------------GTL----------------------GI--APY-A--DIYSV---KV---LDDK----------G-RG--S------------VES-------------------------------------I--------VKG--------------I-----------EW---SI--------------------D-----N------N----------V----DI-----------------------------------------VNISVG---------------L--------------------KK----------------------------SDQKLKRVIDE---------ANEK----GV-----I--------------------------------------------------------------------------------------V---------------VAAAG-NN-------------------------YGLNADY---------------------------------------------------------------------------------------------------------------------------------------P-ARYQ-N---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------KK-------M----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-AKY-----S--A--------R--GK-I----------------------------------------------------------------------D-----F------V-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------LT-TSP---------------------------------------------------------------------------------------------------------------------K--DNY-IN----------------VSG------TSMATPFVS----G---------------------------V------------------IANI----IMQEPVKYSKTKSRFTS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 297
 298 -----------------------------------------------------------S--------------------------K-I--KI--------------A--------------------ILD---------------------------S--------------GIEK-Q------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNLV-----------------------------------------------------------------------------------KKEYN---AI----------EPQQPVI-DVL--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TT-V-----------------------AGIIA----AH-DN-------------------------------KI------------GIT----------------------GV--AASLV--ELYDV---KV---LDDD----------G-KG--K------------IDN-------------------------------------L--------VQG--------------I-----------NW---SI--------------------E-----N------N----------A----DV-----------------------------------------LNISFG---------------M--------------------SS----------------------------NHPELERVVEK---------ALQK----GI-----I--------------------------------------------------------------------------------------V---------------IASAG-NN-------------------------YGGKVEY---------------------------------------------------------------------------------------------------------------------------------------P-ANYK-D---------------------------V---IS---VT--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------HA-------Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HA-ASF-----A--A--------K-NGK-I----------------------------------------------------------------------D-----F------A-----------------A-----P-------------G-----------------VD--------------------------------V------------------------------------------------------------------LT-TKT---------------------------------------------------------------------------------------------------------------------S--NGY-SI----------------ENG------TSLASAHVT----G---------------------------I------------------VSLI----LANKE-TFKLSSNKLKFPKE----------------------------------------------------------------------------------V---------------------YKIL-------EKN-----------------------------------------------------------------------------------------------------AVDIGDS---SQIGNGFIK-------------- 298
 299 ----------------------------------------------------------KS--------------------------K-I--KV--------------A--------------------ILD---------------------------S--------------GIEK-Q------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNLV-----------------------------------------------------------------------------------IKEYN---VI----------EPQHPVI-DVL--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TT-V-----------------------AGIIA----AH-NN-------------------------------KI------------GIT----------------------GV--AASLV--ELYDV---KV---LNDD----------G-KG--K------------IDN-------------------------------------L--------VQG--------------I-----------NW---SV--------------------E-----N------N----------V----DV-----------------------------------------LNISFG---------------M--------------------SS----------------------------NHPELEWVIEK---------AIQK----GI-----V--------------------------------------------------------------------------------------V---------------IAAAG-NN-------------------------YGGKVEY---------------------------------------------------------------------------------------------------------------------------------------P-ANYK-D---------------------------V---IS---VT--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------HA-------Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KV-ASF-----A--A--------R-NGK-I----------------------------------------------------------------------D-----F------A-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------IT-TTT---------------------------------------------------------------------------------------------------------------------S--NGY-SI----------------ENG------TSLATAHVT----G---------------------------I------------------VSLI----LANKE-TFKLSSSKVKFPKE----------------------------------------------------------------------------------V---------------------YKIL-------EKN-----------------------------------------------------------------------------------------------------TVDIG---------------------------- 299
 300 -----------------------------------------NVQK-------LNN-SSNK--------------------------K-I--KI--------------A--------------------ILD---------------------------S--------------GIDK-N------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDTV-----------------------------------------------------------------------------------IKEYN---AI----------NPQEPVT-DTL--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TT-I-----------------------AGILA----AQ-NN-------------------------------TI------------GIS----------------------GI--SSSCV--EIYSV---KV---LNDN----------G-KG--K------------IDN-------------------------------------L--------IRG--------------I-----------NW---SI--------------------D-----N------N----------V----DI-----------------------------------------LNISFG---------------M--------------------SS----------------------------NNVDLENVIKK---------ALQA----GI-----I--------------------------------------------------------------------------------------V---------------VASAG-NN-------------------------YGGNVEY---------------------------------------------------------------------------------------------------------------------------------------P-ANYK-D---------------------------V---IS---VT--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------HT-------Y----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KI-ASF-----T--A--------K-KGK-I----------------------------------------------------------------------D-----F------S-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LT-TSI---------------------------------------------------------------------------------------------------------------------L--NNY-TI----------------EHG------TSLATAHVT----G---------------------------I------------------ISLI----LANHE-KFNLSTNKKNLPKE----------------------------------------------------------------------------------I---------------------YTIL-------EQH-----------------------------------------------------------------------------------------------------SVNIGKK---THYGNGFIK-------------- 300
 301 ----------------------------------------------------------SK--------------------------T-V--KV--------------A--------------------VLD---------------------------S--------------GINQ-D------I-------------K---------G--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGQV-----------------------------------------------------------------------------------KKSYN---AL--------NNTFETEAILD-----------------------------------------------------------------------------------------------------------------------------------------------------HG-------TM-I-----------------------ASIIA----ST-KS-------------------------------RN------------NVV----------------------GI--NPA-V--ELYDV---QV---LNEK----------G-SG--K------------IAD-------------------------------------I--------ISG--------------I-----------NW---SV--------------------E-----Q------G----------V----DI-----------------------------------------INLSFG---------------F--------------------SK----------------------------DDPKLREAIRN---------ASNK----GI-----I--------------------------------------------------------------------------------------I---------------IAATG-NT-------------------------IGLSTDY---------------------------------------------------------------------------------------------------------------------------------------P-AKYP-E---------------------------V---LS---IS--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------KD-------M----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-YAY-----A--G--------Q-G-K-V----------------------------------------------------------------------D-----F------V-----------------A-----P-------------G-----------------VD--------------------------------V------------------------------------------------------------------PV-LNI---------------------------------------------------------------------------------------------------------------------H--GEV-EM----------------QSG------TSYATAYTT----G---------------------------I------------------VSIL----LQNGS-------------KD----------------------------------------------------------------------------------I---------------------EKDL-------RF--------------------------------------------------------------------------------------------------------------------------------------- 301
 302 ----------------------------------------------------------GW--------------------------D-V--KV--------------G--------------------IVD---------------------------T--------------GVDY-R------H-------------P---------A--------------------------------L--------------------------------------G----------------------G------------------------GFGPGFKVA----------------------------------------------------------------------------------------------------------------------------------YG------RDF-AGDAFKPGGVPA-P------------DA-----------------------------------------------------------------------------------------D---PALIVSSQMDC-----------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIA----GS--Y-------------------------------SS------------ADWSFS-------------------GV--APG-V--TLGAY---KV---FGCT----------G-GT--T------------SEL-------------------------------------V--------VAA--------------L-----------DA---AA----------ADG-------------------------------M----QV-----------------------------------------INLSLGDEGA--WG-----------------------------G--------------------------PVAE-----AAAR-L--------AGL----GV-----L--------------------------------------------------------------------------------------V---------------VAAVG-NA--------G-----------PSGLF---MPTS---------------------------------------------------------------------------------------------------------------------------------------A-A--S-A----SG---------------------V---LG---VA--A------------------------------V-----------------------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------RA-------A-PVAA-TLTVSGVRSARA----------------------------------------------------------------------------------------AGRDFAIAAAFGD--------VGSLANAI-----------VRPSDAALIAGVAAVPGSTAA-----TGSADGCSP----------AGQGQTG--GNGATQGSQGRDSSPSMVMV---TGS------LA-SPF-----S--S--------W-G---P--------------------TP------------------------------------------------D-----L------H-----------IEPMLAA-----P-------------G-----------------GA--------------------------------V------------------------------------------------------------------LS-TVP-----------------------------------------------------------------------------------------------IVTRADGSRS-------T--------GY-AY----------------LSG------TSQSAPYVA----A---------------------------A------------------AA-L----YL----Q-------AN------------------------------------------------------------------------------------------------------------KARQ-------VSA-------------------------AQ------------------------------------------------------------------------L---------------------------------- 302
 303 METVP-Y----------IGAT---------------PDV-----Q-------AAG-FRGK--------------------------D-V--RV--------------A--------------------VLD---------------------------S--------------GIDY-T------H-------------A---------A--------------------------------F--------------------------------------G----------------------GPGTLEAYQAAYGTSPSDSRNKTLDGLFPTDRVK----------------------------------------------------------------------------------------------------------------------------------GG------YDF-VGEVW-PNGPLA-P------------DP-----------------------------------------------------------------------------------------D---P-------IDCGAPGLSSGTCAG--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ADIIG----GE-----------------------------------------------------Q-------------------GV--APE-V--DLFAV---KV-----CS----------A-VS--S------------SCS-------------------------------------G--------VAI--------------LQGLDWSADPNGDG---VT----------DDR-------------------------------M----HI-----------------------------------------VNMSLG--AS--YG-QNY---D---------------------D--------------------------DSAI-----AVDN-L--------QPL----GI-----L--------------------------------------------------------------------------------------V---------------VASAG-NS--------AD---------RP---Y---ITGT---------------------------------------------------------------------------------------------------------------------------------------P-A--G-A----RT---------------------A---LS---VAQTA------------------------------V-----------------------------P------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------DA-------SYPITVLSTTVYGIAQPWAPIPN----------------------------------------------------------------------------------TPVNGTLVYGASLGNALGCTAYPAGSLTGQILLVDRGVCAISIKGSNGAAAGAVAVIVANNAAGAVPPTFSFGGGTPTVPVLSITQAAGNALKARVGNATTIGFDTPATNAGSVVG---T-------------------S--S--------R-G---P--------------------TL------------------------------------------------G-----Q------MTYGDQIMYGQIIKPEIGA-----P-------------------------------GA--------------------------------S------------------------------------------------------------------LS-AV------------------------------------------------------------------------------------------------------AGSG-------T--------GV-EP----------------FGG------TSGAAPMVA----G---------------------------A------------------AA-L----LY----N-------AVDWSF-------------------------------------------------------------A---PWE--------------L---------------------KARL-------INT-------------------------AE------------------------------------------------------------------------TNIFNGPPVFVGPAL--APITRIGGGEVRINRAIA 303
 304 -----------------------------QWDMRRITHNGESYKL-------HSP-S-GK----------------------------V--SV--------------A--------------------LID---------------------------S--------------GYPE-N------H-------------P---------D--------------------------------FKS--------------ISMG-K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GYKGNEPAETGNIDQLTDLT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TG-V-----------------------LSQVN----A---D-------------------------------GL------------MK-----------------------GV--APG-I--PVNLY---RV---F-GK----------S-SA--D------------TTW-------------------------------------I--------IKG--------------I-----------IE---AA--------------------K-----D------E----------N----DV-----------------------------------------INISAGSYLLKNGK-YSDDG---------------D------NN--------------------------SSEIKAYKKAINY---------ANKK----GS-----I--------------------------------------------------------------------------------------V---------------VSALG-NDSIN--LNNN-SELLDFLNNQIKDKGR---TAIGTVENI---------------------------------------------------------------------------------------------------------------------------------P-AQL-AN---------------------------V---IS---VA--S------------------------------TGP------------------------DKEI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSY-----S--N--------Y-GK-------------------------------------------------------------------------NTID--F------T-----------------A-----P-------------G-----------------GDIKLLNKFGTDVW----------MRDEMFKKEAI------------------------------------------------------------------LV-AHP-------------------------------------------------------------------------------------------------------------------Q----GGY-YY----------------NFG------NSLATPKVS----G---------------------------A------------------LALV----IDKY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 304
 305 -------------------------IWDVQWDIKRITNNGESYKL-------HSP-S-GK----------------------------V--SV--------------A--------------------LID---------------------------S--------------GYPE-N------H-------------P---------D--------------------------------IKS--------------ISIQ-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GYKGNEENETGNIHQLTDRT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------LSQVN----A---D-------------------------------GL------------MK-----------------------GV--APG-M--PVNMY---RV---F-GE----------N-SA--E------------GSW-------------------------------------I--------IKG--------------I-----------IE---AA--------------------K-----D------K----------N----DV-----------------------------------------INISAGSYLLKNGT-YSDGS---------------G------NN--------------------------RAEIKAYEKAIHY---------ANKK----GS-----I--------------------------------------------------------------------------------------V---------------VSALG-NDSIN--ININ-SELLSILNSKIKDEGK---SATGIVQDI---------------------------------------------------------------------------------------------------------------------------------P-AQL-AQ---------------------------V---VS---VA--S------------------------------TGM------------------------DSKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSF-----S--N--------Y-GK-------------------------------------------------------------------------NIID--F------T-----------------A-----P-------------G-----------------GDIKLLNKFGADVW----------MAEEMFKKEMI------------------------------------------------------------------LV-AHP-------------------------------------------------------------------------------------------------------------------Q----GGY-YF----------------NYG------NSLATPKVS----G---------------------------A------------------LALV----IDKY-----------GYKNK-----------------------------------------------------------------PNK--------------A---------------------INHL-------KRN-----------------------------------------------------------------------------------------------------TN-----------AENEIDLYKAL--------- 305
 306 ---------------KASVYTNSHDFWDYQWDMKYVTNNGESYAL-------YQP-S-KK----------------------------I--SV--------------G--------------------IID---------------------------S--------------GIME-E------H-------------P---------D--------------------------------LSN--------------SLGN-Y-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FKNL-------------------------------------V----PKG-------------------------GFDNEEPDETGNPSDIVDKM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-V-----------------------AGQIT----A---N-------------------------------GN------------IL-----------------------GV--APG-I--TVNIY---RV---F-GE----------N-LS--K------------SEW-------------------------------------V--------ARA--------------I-----------RR---AA--------------------D-----D------G----------N----KV-----------------------------------------INISAGQYLMISGS-YDDG----------------T------ND--------------------------YQEYLNYKSAINY---------ATAK----GS-----I--------------------------------------------------------------------------------------V---------------VAALG-NDSLN--IQDN-QTMINFLKRFRSI------KVPGKVVDA---------------------------------------------------------------------------------------------------------------------------------P-SVF-ED---------------------------V---IA---VG--G------------------------------IDG------------------------YGNI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDF-----S--N--------I-GA-------------------------------------------------------------------------DA----I------Y-----------------A-----P-------------A-----------------GTTANFKKYGQDKF----------VSQGYYLKDWL------------------------------------------------------------------FT-TAN-------------------------------------------------------------------------------------------------------------------T----GWY-QY----------------VYG------NSFATPKVS----G---------------------------A------------------LALV----VDKY-----------GIKN------------------------------------------------------------------PNQ--------------L---------------------KRFL-------LMN-----------------------------------------------------------------------------------------------------SP--------EVNGNRVLNIVDLLN-------- 306
 307 -------------------------IWENQWDMQQVTHNGDSYRL-------YPG-T-KN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GIDI-N------H-------------P---------D--------------------------------LIN--------------NISP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GFRGQESQETGELNRLIDLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TF-T-----------------------AGQIA----A---N-------------------------------GF------------MK-----------------------GI--APG-I--GIKMY---RV---F-GN----------G-AG--E------------AIW-------------------------------------V--------IKA--------------I-----------VE---AA--------------------K-----D------N----------V----DV-----------------------------------------INLSLGEYLINGIV-SSSDGES-------------S------EE--------------------------LSEIRAYKKAIKY---------AKSK----GS-----V--------------------------------------------------------------------------------------I---------------VAAAG-NDGLN--VTNK-QEMNDFFRKKNENTGV---TYNGEVLDV---------------------------------------------------------------------------------------------------------------------------------P-AEL-PN---------------------------V---VT---VS--S------------------------------VGP------------------------SKLL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------Y-GE-------------------------------------------------------------------------NFID--I------A-----------------A-----P-------------G-----------------GDNRLFQQYGLEQW----------VKNKLMLKELI------------------------------------------------------------------LT-TAP-------------------------------------------------------------------------------------------------------------------G----GGY-AL----------------SVG------VSLAAPKVS----G---------------------------A------------------LALI----IDKN-----------NLKKD-----------------------------------------------------------------PDK--------------A---------------------VRYL-------YKN-----------------------------------------------------------------------------------------------------GVSNDTPTNKSLYGNGLLDVYKAVS-------- 307
 308 ----------------------------------------------------------KN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GIDI-N------H-------------P---------D--------------------------------LKD--------------NISP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GFREQESQETGELNRLIDLR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-I-----------------------AGQVA----A---N-------------------------------GF------------MK-----------------------GV--APG-I--GIKMY---RV---F-GN----------G-AG--E------------AIW-------------------------------------V--------IKA--------------I-----------VE---AA--------------------K-----D------N----------V----DV-----------------------------------------INLSLGEYLINGIV-SSSDGES-------------S------EE--------------------------LSEIKAYKKAIKY---------AKSK----GS-----V--------------------------------------------------------------------------------------I---------------VAAAG-NDALD--VTNK-QEMNDFFRKKNENTGV---TFTGEVLDV---------------------------------------------------------------------------------------------------------------------------------P-AEF-PN---------------------------I---VT---VS--S------------------------------VGP------------------------SKLL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------Y-GE-------------------------------------------------------------------------SFID--I------A-----------------A-----P-------------G-----------------GDNRLFQQYGLEEW----------VKNKLMLKELI------------------------------------------------------------------LT-TAP-------------------------------------------------------------------------------------------------------------------G----GGY-AL----------------SVG------VSLAAPKVS----G---------------------------A------------------LALI----IDKN-----------NFKNN-----------------------------------------------------------------PDK--------------A---------------------VKYL-------YKN-----------------------------------------------------------------------------------------------------GVRNDNHINKSFYGNGLL--------------- 308
 309 ------------------------------------------YDV-------FSG-S-KN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GVDS-N------H-------------P---------D--------------------------------LKG--------------NIVP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PNG-------------------------GFRGKEKSETGDINYFEDKT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-T-----------------------AGQIA----A---N-------------------------------GN------------IK-----------------------GI--APN-I--GIKSY---RV---F-GE----------G-LG--E------------SIW-------------------------------------I--------IKG--------------I-----------IQ---AA--------------------K-----D------D----------V----DV-----------------------------------------INLSLGQYLVDGKV-FLNSSES-------------K------KD--------------------------LAEIKAYKRAIKF---------ARNE----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NDSLN--VNDS-RQMNEIYKKKNTLHEV---SYTGKVLDV---------------------------------------------------------------------------------------------------------------------------------P-AAL-PN---------------------------V---VT---VS--S------------------------------VGL------------------------ENEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVF-----S--N--------Y-GE-------------------------------------------------------------------------GFID--I------A-----------------A-----P-------------G-----------------GDLKLFNELGIEQY----------YSSGAFKKEQV------------------------------------------------------------------VG-TAP-------------------------------------------------------------------------------------------------------------------G----GGY-SF----------------SVG------NSVAAPKVS----G---------------------------A------------------LALI----IDKK-----------NYKNQ-----------------------------------------------------------------PNK--------------S---------------------TNFL-------YQH-----------------------------------------------------------------------------------------------------GV-NGYEEKYSFFGHGTLDVYKAV--------- 309
 310 -------------------------LWESQWDMKKITNNGESYNV-------FSG-S-KN----------------------------V--IV--------------G--------------------IVD---------------------------S--------------GLDT-N------H-------------P---------D--------------------------------LKS--------------NIVV-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PLG-------------------------GYKGEEPEETGDVNQLTDFL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------AGLVA----A---N-------------------------------GI------------IK-----------------------GV--APE-I--GIKSY---RV---F-GK----------K-SG--D------------TAW-------------------------------------V--------IKG--------------I-----------VE---AA--------------------K-----D------D----------V----DV-----------------------------------------INLSLGSYLVNGTT-FSANGKS-------------K------KD--------------------------IADIKAYKKAINF---------ARKQ----GS-----I--------------------------------------------------------------------------------------V---------------VAAAG-NDALN--MRDK-KQVAEFYNKKYEKDGI---TFKGEVLDV---------------------------------------------------------------------------------------------------------------------------------P-AGL-PN---------------------------V---VT---VS--S------------------------------IGP------------------------SNEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SMF-----S--N--------Y-GE-------------------------------------------------------------------------NFVD--I------A-----------------A-----P-------------G-----------------GDTRLLDTYGKDAW----------INDKWFAKESI------------------------------------------------------------------LS-TFP------------------------------------------------------------------------------------------------------------------------GGY-SY----------------SSG------VSTAAPKVS----G---------------------------A------------------LALI----IDKY-----------HFKDK-----------------------------------------------------------------PNE--------------A---------------------TKFL-------YKY-----------------------------------------------------------------------------------------------------GV-DNRVKNKEQFGNGILDVYKAVT-------- 310
 311 -----------------------------------------------------TG-T-HN----------------------------V--VV--------------G--------------------IID---------------------------S--------------GIDV-N------H-------------P---------D--------------------------------LAK--------------NILS-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GYRGMEESETGDINYLDDKR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------AGLIA----A---N-------------------------------GL------------MK-----------------------GV--APG-I--GVRAY---RV---F-GG----------K-SA--E------------PIW-------------------------------------I--------AKA--------------I-----------IE---AA--------------------K-----D------D----------V----DV-----------------------------------------INLSLGSYLVDGTI-YSKEGAS-------------K------KE--------------------------AAEIKAYKKAIKY---------AKKQ----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NDGID--VTNY-QMMDKLIKERLLQDDL---TYKGMGLDV---------------------------------------------------------------------------------------------------------------------------------P-ASL-SN---------------------------V---IT---VG--S------------------------------TGP------------------------TQEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------Y-GL-------------------------------------------------------------------------GFSD--V------T-----------------A-----P-------------G-----------------GDLRLFNKFGSDAY----------MKEGWFRKEQV------------------------------------------------------------------IS-TRP-------------------------------------------------------------------------------------------------------------------R----GGY-YY----------------GAG------TSTAAPKVS----G---------------------------A------------------LALI----IDKY-----------KFKNS-----------------------------------------------------------------PNE--------------A---------------------TREL-------YKY-----------------------------------------------------------------------------------------------------GV-NKTPLDALFFGKGKLDIYNAI--------- 311
 312 --------------------------------------------I-------YPG-T-KN----------------------------V--TV--------------G--------------------IVD---------------------------S--------------GLDF-N------H-------------P---------D--------------------------------LKN--------------NIIE-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PSG-------------------------GFQGGEIEETGDINQINDIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TL-V-----------------------AGQIA----A---N-------------------------------GR------------IK-----------------------GV--APG-I--GIKSY---RA---L-GK----------K-KS--E------------NIW-------------------------------------I--------IKG--------------I-----------VE---AA--------------------K-----D------D----------V----DV-----------------------------------------INVSLGSYLINGIV-HSNNDRS-------------V------NN--------------------------LAEIEGYKRAIQF---------AKNQ----GS-----V--------------------------------------------------------------------------------------V---------------VAAVG-NDSLN--LKDN-KQMHEFFKGKAEDEM----DMSSKIFDA---------------------------------------------------------------------------------------------------------------------------------P-ASF-ND---------------------------V---VA---VA--S------------------------------VNM------------------------KDEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIF-----S--N--------Y-GE-------------------------------------------------------------------------GIID--I------V-----------------A-----P-------------G-----------------GDLRLYKQYGENDW----------INKGFYLQETI------------------------------------------------------------------FS-TWP------------------------------------------------------------------------------------------------------------------------GGY-FT----------------TYG------NSLAAPKVS----A---------------------------T------------------LALI----IDQN-----------KYKNQ-----------------------------------------------------------------PEK--------------S---------------------IDFL-------YKY-----------------------------------------------------------------------------------------------------GV-KSTIKNSRLYGHGILDVDNAV--------- 312
 313 -------------------------KFDYQWDMKKITNDGESYKI-------YPG-T-KN----------------------------V--SV--------------G--------------------VID---------------------------T--------------GLDV-E------H-------------P---------D--------------------------------LKE--------------NIIS-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNF-------------------------------------V----PYK-------------------------GFRGEELYESGNINYLNDLS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TN-T-----------------------AGQIA----A---N-------------------------------GA------------LK-----------------------GV--APG-V--GIRAY---RV---F-GQ----------R-EA--E------------SIW-------------------------------------I--------IKA--------------I-----------VE---AA--------------------K-----D------D----------V----DV-----------------------------------------INLSLGDYLLSGKY-FSNGKYI-------------S------SD--------------------------IPEIEGYQRAVDF---------AMKL----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NDGLN--VKDT-LKMNHFFKSYLESNAIENTNFFGKIKDI---------------------------------------------------------------------------------------------------------------------------------P-ADL-SG---------------------------V---VT---VS--S------------------------------IGS------------------------TDEF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIF-----S--N--------Y-GD-------------------------------------------------------------------------GFVD--I------V-----------------A-----P-------------G-----------------GDYRLLNTYGPEIW----------SKNKMYEKEQI------------------------------------------------------------------LT-TAP-------------------------------------------------------------------------------------------------------------------D----GDY-IY----------------QAG------NSLAAPKVA----G---------------------------T------------------LALI----IDKN-----------HLKNN-----------------------------------------------------------------PYS--------------A---------------------IDFL-------YKH-----------------------------------------------------------------------------------------------------GV-----DKNNNFGYGILNVYKA---------- 313
 314 --------------------------------------------I-------FPG-T-KN----------------------------V--GV--------------A--------------------IID---------------------------S--------------GLDI-E------H-------------P---------D--------------------------------LKN--------------NVLD-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNF-------------------------------------V----PVG-------------------------GFRGEELNENGERDRIDDLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-V-----------------------AGQVA----A---N-------------------------------GL------------IK-----------------------GV--APG-V--GIKAY---RV---F-GE----------R-EA--E------------TIW-------------------------------------I--------IKA--------------I-----------VE---AA--------------------K-----D------N----------S----DV-----------------------------------------INLSLGDYLLEGEY-ILNGKKI-------------A------SD--------------------------LPEIEGYKRAIKF---------ASRL----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NEGLN--VRNQ-NQMNDFFKKHLEIYDLGDISFKGVIRDI---------------------------------------------------------------------------------------------------------------------------------P-ADL-PG---------------------------V---VS---VS--S------------------------------IGN------------------------DNTL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAF-----T--N--------Y-GN-------------------------------------------------------------------------RFTD--I------V-----------------A-----P-------------G-----------------GDNKLLNQYGGEVW----------YKNKMYEREHV------------------------------------------------------------------LT-TAP-------------------------------------------------------------------------------------------------------------------N----GEY-VY----------------QFG------NSVAAPKVS----G---------------------------A------------------LALI----IDKQ-----------NLKNR-----------------------------------------------------------------PNE--------------S---------------------IRYL-------YKY-------------------------------------------------------------------------------------------------------------------------------------- 314
 315 -----------------------------------------------------QG-S-TN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GIFS-D------H-------------P---------D--------------------------------LKN--------------SLLP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GLNGTESSETGDINQIDDIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------AGQIT----A---N-------------------------------GL------------MK-----------------------GA--APG-V--GIKAY---RV---F-GS----------K-SA--E------------TIW-------------------------------------V--------IKA--------------I-----------IE---AA--------------------N-----D------D----------I----DV-----------------------------------------INLSLGDYLLKSGS-YSHTG---------------K------ND--------------------------SVEIEAYKQAINY---------AYKK----GS-----I--------------------------------------------------------------------------------------V---------------VAAAG-NDGID--VNNQ-TKLHDVVNANLKHSNT---TVSGIILDM---------------------------------------------------------------------------------------------------------------------------------P-GAL-TN---------------------------V---VT---VG--S------------------------------IGP------------------------TGEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------Y-GK-------------------------------------------------------------------------NFID--I------I-----------------S-----P-------------G-----------------GDFRLLEQYGEDKW----------IKDYLIEKEQI------------------------------------------------------------------LT-TNV-------------------------------------------------------------------------------------------------------------------D----GGY-YY----------------DSG------TSLAAAKVS----G---------------------------A------------------LALI----AEKN-----------KWKDQ-----------------------------------------------------------------PHR--------------V---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------- 315
 316 -----------------------------------------------------QG-S-TN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GIFP-Y------H-------------P---------D--------------------------------LKN--------------SLLP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GLKGRESSETGDINKIDDLL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------AGQIA----A---N-------------------------------GL------------MK-----------------------GV--APG-V--GIKVY---RV---F-GS----------T-SA--E------------TIW-------------------------------------V--------IKA--------------I-----------IE---AA--------------------N-----D------D----------V----DV-----------------------------------------INLSLGDYLLKSGS-YSHTG---------------R------ND--------------------------SVEIEAYKQAINY---------AYKK----GS-----I--------------------------------------------------------------------------------------V---------------VAAAG-NDGID--VNDQ-AKFHEVVNANLKTSNT---TVSGIILDM---------------------------------------------------------------------------------------------------------------------------------P-GAL-TN---------------------------V---VT---VS--S------------------------------IGP------------------------TGEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------H-GK-------------------------------------------------------------------------DFID--I------I-----------------S-----P-------------G-----------------GDFRLLEQYGEDMW----------INDHLIEQEQI------------------------------------------------------------------LT-TNI-------------------------------------------------------------------------------------------------------------------N----GGY-YY----------------DSG------TSLAAAKVS----G---------------------------A------------------LALI----VEKN-----------NWKDQ-----------------------------------------------------------------PHR--------------A---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------- 316
 317 -----------------------------------------------------SG-S-KN----------------------------V--TV--------------G--------------------IID---------------------------S--------------GLDM-E------H-------------P---------D--------------------------------LKN--------------NIIE-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKN-------------------------GFRGKERDESGDPNELTDKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGQIA----A---N-------------------------------GK------------LK-----------------------GV--APN-I--SIKSY---RV---F-GK----------R-TA--E------------SLW-------------------------------------I--------VKG--------------I-----------IE---AA--------------------K-----D------D----------V----DV-----------------------------------------INVSLGDYLIDGVA-FLEQQGP-------------K------TN--------------------------VAEVKAFKDAIEF---------AEKQ----GS-----I--------------------------------------------------------------------------------------V---------------VAAAG-NNALD--VNNK-DIMYKFLQKKLRNDGI---KLDGEVLDV---------------------------------------------------------------------------------------------------------------------------------P-AAL-PG---------------------------V---VT---VS--S------------------------------VGP------------------------SNEL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLF-----S--N--------F-GD-------------------------------------------------------------------------GFID--I------A-----------------A-----P-------------G-----------------GDNRLYQQYDFDTW----------NNQKMYEIEKV------------------------------------------------------------------IS-TGP-------------------------------------------------------------------------------------------------------------------D----QDY-FY----------------DAG------NSTAAPKVS----G---------------------------T------------------LALI----VGQR-----------NLKDQ-----------------------------------------------------------------PKE--------------A---------------------IDYL-------YNH-----------------------------------------------------------------------------------------------------GV-DYVENSTSSFGHGILNVYKV---------- 317
 318 -------------------------LWDKQWDMKKITNNGKSYDV-------FSG-S-KN----------------------------V--VV--------------G--------------------IID---------------------------S--------------GLDM-N------H-------------P---------D--------------------------------LKN--------------NIVT-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNL-------------------------------------V----PKG-------------------------GFRGKEKEEDGDINNSIDKL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TY-V-----------------------SGQIA----A---N-------------------------------GK------------IK-----------------------GV--APN-V--GIKSY---RV---F-GE----------R-TA--E------------SLW-------------------------------------I--------IKG--------------I-----------IE---AA--------------------K-----D------D----------V----DV-----------------------------------------INISLGDYLIDGMA-FLENQPT-------------K------ND--------------------------IAEIKAFKEAIEF---------AEKQ----GS-----V--------------------------------------------------------------------------------------V---------------VAAAG-NNSLD--VNNK-KQMYQFLQKKLRNDGI---TLQGNLIDV---------------------------------------------------------------------------------------------------------------------------------P-ASL-PG---------------------------V---VT---VS--S------------------------------IGP------------------------SNNL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASF-----S--N--------F-GK-------------------------------------------------------------------------DFID--I------A-----------------A-----P-------------G-----------------GDNRLFQRYGFETW----------SDQKMYEKEQV------------------------------------------------------------------IS-TGL-------------------------------------------------------------------------------------------------------------------E----QDY-IY----------------DAG------NSVAAPKIS----G---------------------------A------------------LALI----IDKK-----------KFKNQ-----------------------------------------------------------------PEQ--------------S---------------------VNYL-------YNH-----------------------------------------------------------------------------------------------------GV-DYVPHAESLMGKGVLNVFKLL--------- 318
 319 -------------------------LWDMQWDMKEITHNGESYKK-------ETG-S-HN----------------------------V--VV--------------G--------------------IID---------------------------S--------------GVDV-D------H-------------P---------D--------------------------------LVK--------------NLIP-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNF-------------------------------------V----PKG-------------------------GLRGTEPEETGDINNINDIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TL-V-----------------------SGSIA----A---N-------------------------------GE------------LK-----------------------GV--APD-T--GIRAY---RV---F-GN----------K-SA--D------------AAW-------------------------------------V--------INA--------------I-----------IE---AA--------------------K-----D------D----------V----DV-----------------------------------------INLSLGSYYVNGKV-YENGKLV-------------D------NG--------------------------WAEVEGYKRAIEY---------ANQH----GS-----V--------------------------------------------------------------------------------------V---------------VASAG-NDSVN--VANK-QELNNFLKQKYEKEGK---IFTGVGIEA---------------------------------------------------------------------------------------------------------------------------------P-GEL-PG---------------------------V---VT---VS--S------------------------------TGP------------------------TGQR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVF-----S--N--------Y-GE-------------------------------------------------------------------------GVID--I------S-----------------A-----P-------------G-----------------GDYRLWQQYGEEVW----------WNTGLFRQEEV------------------------------------------------------------------LT-TFN-------------------------------------------------------------------------------------------------------------------T----GRY-LF----------------AAG------TSMAVPKVS----A---------------------------T------------------LALI----INHY-----------NFKNQ-----------------------------------------------------------------PKR--------------S---------------------ISHL-------YKN-----------------------------------------------------------------------------------------------------GIKKDIAPDKASWGNGQLDVYNAI--------- 319
 320 -----------------------------------------------------KG-S-KK----------------------------T--VV--------------G--------------------IID---------------------------S--------------GIDK-N------H-------------L---------D--------------------------------LKD--------------NVLS-V-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-NF-------------------------------------V----PKG-------------------------GLRGQEPYENGEINNSTDYL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGQIA----A---N-------------------------------GQ------------MK-----------------------GI--APE-T--GIRSY---RV---F-GG----------K-SA--D------------TVW-------------------------------------I--------INA--------------I-----------IQ---AA--------------------K-----D------D----------V----DV-----------------------------------------INISLGTFLVNSKG-KNNGKPV-------------T------DD--------------------------LAEIKAFRKAVAF---------AHRK----GS-----A--------------------------------------------------------------------------------------V---------------VASIG-NEGLN--LKDK-KAVYDYWKNNINQEGR---FMNAKVILI---------------------------------------------------------------------------------------------------------------------------------P-AQL-PN---------------------------V---VT---VA--S------------------------------VGP------------------------NGNR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVF-----S--N--------Y-GK-------------------------------------------------------------------------NIAD--I------A-----------------A-----D-------------G-----------------GDHRILNEVGAEKY----------YQEGLFRQEYI------------------------------------------------------------------LG-AAP-------------------------------------------------------------------------------------------------------------------G----SSY-TF----------------SVG------TSIAAPKIS----G---------------------------A------------------LALL----IDQR-----------YLHDK-----------------------------------------------------------------PDK--------------G---------------------IRIL-------LKN--------------------------------------------------------------------------------------------------------ADKYDSNDYIGKGVLNIYKA---------- 320
 321 ---------------------------------------------------LNN-KKNGSHDLFDRQWDMRKITNEGKSYKLSPDRKKA--KV--------------A--------------------LVD---------------------------S--------------GVNS-S------HTDLKSINKIVNEVPKNGFRGSEND---------------------ESGNKNFEEDKL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TL-V-----------------------AGQIG----A---N------------------------------------------------------------------GNLKGV--NPG-V--EMNVY---RV---FGSKK-SEMLWVSKG----------------------------------------------------------I--------IDA-----------------------------------------------------------------------------ANDDNDV-----------------------------------------INVSLGNYLIKDNQ--------------------------------------------------------NKKKLRDDEKVDYDALQKAINYAQKK----GS-----I--------------------------------------------------------------------------------------V---------------VAAVG-NDGINVKKVKEINKKRNLNSKTSKKVYDS--------------------------------------------------------------------------------------------------------------------------------------------PANLNN-----------------------------V---MT---VG--S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDDNDY-ISEF-----SNYG-------------------------------------------------------------------------------------NNFIDLM------------------------TIGGSYKLLDKYGKDAWLEKG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YMQKQSVLSTSSNGRYIYQSG------TSLAAPKVS----G---------------------------A------------------LAL-----------EIDKYQLKDQPETA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IELFKKKGIEKEKYMDKKHYGNGKLDVYKLLK-------- 321
 322 --------------------------------IDAVTANKKSYEF-------QMG-N-HE----------------------------V--TV--------------A--------------------IID---------------------------S--------------GIDP-N------H-------------P---------D--------------------------------LKN--------------NIVA-G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKSF-------------------------------------I----PGD--------------------------------------ESINDNT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-V-----------------------AGIIA----A---N-------------------------------GD------------LK-----------------------GI--APN-T--GIAPY---KV---LNS-----------E-GG--Q------------STW-------------------------------------V--------IKA--------------I-----------IQ---AV--------------------D-----D------G----------H----EI-----------------------------------------INLSLGTFLSLKNK----------------------------EE--------------------------KALIKAYNRAINY---------AHKK----GT-----L--------------------------------------------------------------------------------------V---------------VASAG-NQGID--LSNP-RKVSEQLG-----------ILNDEQKYA---------------------------------------------------------------------------------------------------------------------------------P-GGL-NS---------------------------A---LS---VG--A------------------------------VDK------------------------NNQF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENY-----S--N--------Y-GW-------------------------------------------------------------------------M-LD--I------T-----------------A-----P-------------G-----------------GD------FGPLYE----------KEGIVDVRHLI------------------------------------------------------------------LT-TYP---------------------------------------------------------------------------------------------------------TYLP-NYIAENGDLPRGY-EF----------------SYG------TSLSTPTVS----A---------------------------V------------------AALI----LTEYKEE-------KSKNLS-----------------------------------------------------------------IDE--------------I---------------------QNIM-------YQT-----------------------------------------------------------------------------------------------------TLKVGTNRKEKLSGRGTVDAYEA---------- 322
 323 ------------------------------WQIAKVTNNYKSHEI-------TLG-E-KN----------------------------V--NI--------------A--------------------LVD---------------------------S--------------GVDY-N------H-------------P---------E--------------------------------LKD--------------SIRYLE-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKSY-------------------------------------V----PSE--------------------------------------PDLLDQN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-V-----------------------AGIIA----A---H-------------------------------DK------------LK-----------------------GI--VPN-I--TITPY---KV---IGK-----------K-DG--E------------SVW-------------------------------------T--------IQA--------------I-----------ID---AA--------------------N-----K------G----------A----DV-----------------------------------------INLSLGTYKAINLE----------------------------DE--------------------------NAIIKAYERAIQY---------AKEK----NS-----I--------------------------------------------------------------------------------------V---------------VASAG-NEGIS--LDKPFEKVDDEKG-----------VLYK--IHV---------------------------------------------------------------------------------------------------------------------------------P-GGL-SN---------------------------V---LT---VS--G------------------------------TDK------------------------NDEF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNY-----S--N--------F-GP-------------------------------------------------------------------------E-VD--F------S-----------------A-----P-------------S-----------------GS------YGTIID----------NQFKFDPSYLI------------------------------------------------------------------GT-TYP---------------------------------------------------------------------------------------------------------TYLEPTMLDVQLNTPKGY-TL----------------NLG------TSLSAPSVS----G---------------------------T------------------LGAI----ISRYYEL-------HSTKPS-----------------------------------------------------------------SDI--------------T---------------------IKYL-------KDG-----------------------------------------------------------------------------------------------------ATDLGATGKDDQYGYGLVNSYKS---------- 323
 324 -----------------------------GWDIKKITEDGKSFKK-------QKG-N-HN----------------------------V--KI--------------A--------------------LID---------------------------S--------------GIDF-N------H-------------P---------D--------------------------------LKD--------------NIIS-K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKSF-------------------------------------V----PNI--------------------------------------DNTDDNM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-A-----------------------AGSIA----A---N-------------------------------GN------------ML-----------------------GV--GPN-L--GIIPY---KV---MDNW----------Q-DG-AE------------SAW-------------------------------------V--------TQA--------------I-----------IA---AA--------------------N-----D------G----------V----DV-----------------------------------------INLSLGTYKSLNKP----------------------------ED--------------------------QVVIESYKRAVKY---------AHKR----GV-----I--------------------------------------------------------------------------------------V---------------VASAG-NESLD--NTNP-ALIAEKRG-----------FSGDMQVHL---------------------------------------------------------------------------------------------------------------------------------P-GGGVPS---------------------------L---LT---VS--A------------------------------TDK------------------------DDLL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSY-----S--N--------Y-G--------------------------------------------------------------------------G-IS--V------A-----------------A-----P-------------A-----------------GD------YGPEWA----------TQQKLDPFSMT------------------------------------------------------------------LT-TYP---------------------------------------------------------------------------------------------------------TNLPQPPISKALNLPEGY-VL----------------MAG------TSVAAPKVS----G---------------------------A------------------VGVL----IAEQQKS-------GRKPLT-----------------------------------------------------------------LAK--------------L---------------------EKIL-------KNS-----------------------------------------------------------------------------------------------------STDLGAYGKDPKYGYGLINVNKAL--------- 324
 325 ----------------------------LGWDIKKITEDGKSFKK-------QKG-N-HN----------------------------V--KV--------------A--------------------LID---------------------------S--------------GVDF-N------H-------------P---------D--------------------------------LKE--------------NIIS-K-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GRSF-------------------------------------V----PNV--------------------------------------DNTEDHM--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-A-----------------------AGTIA----A---N-------------------------------GN------------ML-----------------------GV--GPE-L--GIIPY---KV---MDNW----------Q-DG-AE------------SAW-------------------------------------V--------TQA--------------I-----------IT---AT--------------------K-----D------G----------V----DV-----------------------------------------INLSLGTYKSLEKP----------------------------ED--------------------------RVVVESYKRAVKY---------AHKH----GV-----I--------------------------------------------------------------------------------------V---------------VASAG-NESFD--NNNP-TLIAEKRG-----------FSGDKQVHL---------------------------------------------------------------------------------------------------------------------------------P-GGGVPS---------------------------L---IT---VS--A------------------------------TDK------------------------NDIL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----S--N--------Y-G--------------------------------------------------------------------------G-VS--V------A-----------------A-----P-------------A-----------------GD------YGPEWV----------TEQKLDPLSMT------------------------------------------------------------------LT-TYP---------------------------------------------------------------------------------------------------------TNLPQPPLSKALNLPEGY-VL----------------MVG------TSVAAPKVS----G---------------------------A------------------VGVL----IAEQQKR-------GQKSLS-----------------------------------------------------------------VAQ--------------I---------------------KNIL-------KKS-----------------------------------------------------------------------------------------------------STDLGAPGKDPQYGYGLINVNKAL--------- 325
 326 ------------------------------------------------------G-S-HN----------------------------T--KV--------------G--------------------IID---------------------------S--------------GIDF-N------H-------------P---------D--------------------------------LKK--------------NIVD-T-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GESF-------------------------------------V----PVE--------------------------------------DNTQDFY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-V-----------------------AGIIA----A---N-------------------------------GD------------VK-----------------------GV--GPN-L--GLVPY---KV---FD------------K-DGKSK------------RSW-------------------------------------V--------ISA--------------I-----------VK---AT--------------------E-----D------D----------M----DV-----------------------------------------INLSLSTFLSKKDK----------------------------DD--------------------------RETIKLFEKAFKF---------ARKH----NT-----L--------------------------------------------------------------------------------------I---------------VAAAG-NHGYD--ISNS-KKLAQQLG-----------KPKDNILHL---------------------------------------------------------------------------------------------------------------------------------P-GGD-ND---------------------------V---IT---VS--A------------------------------TTA------------------------QNTK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----S--N--------Y-GK-------------------------------------------------------------------------N-IS--I------A-----------------A-----P-------------G-----------------GD-----------L----------DTNKIDLYSLV------------------------------------------------------------------WT-TSP---------------------------------------------------------------------------------------------------------VNIPQTPLSKSLGFQKGY-EP----------------TLG------TSVAAPIVT----A---------------------------T------------------AALL----KTEYYEK-------YGEEMP-----------------------------------------------------------------NRK--------------V---------------------EENL-------YQN-----------------------------------------------------------------------------------------------------TDHVENLDKN-EVGSGIVN-------------- 326
 327 ----------------INQTIQLPQLFSYQWDMQKITNNGVSYSL-------NKE-NRKN----------------------------V--TV--------------A--------------------LVD---------------------------S--------------GIDV-D------H-------------N---------A--------------------------------FTG--------------MIDS-R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKNF-------------------------------------V----PAG-------------------------GYDNSESSETGNINDIDDKK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------AGQIA----A---N-------------------------------GQ------------IF-----------------------GV--SPG-T--NLLIY---RV---F-GK----------S-KS--K------------ECW-------------------------------------I--------LKA--------------I-----------ID---AT--------------------N-----N------G----------A----NV-----------------------------------------INLSLGQYI--------------------------KIPNGDIWE--------------------------SAEALGYKFAIDY---------ATRH----NV-----I--------------------------------------------------------------------------------------V---------------VAATG-NDGLS---DDN-GEVKTYYNSQHSGQDM---SQNDTVEDY---------------------------------------------------------------------------------------------------------------------------------P-SVL-PN---------------------------A---IA---VG--S------------------------------SDN------------------------NNQR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSF-----S--N--------Y-YN-------------------------------------------------------------------------QYQDNFI------L-----------------A-----P-------------G-----------------GGTTLLDQYGQEEW----------YNQKLFMKEQV------------------------------------------------------------------LS-TSN-------------------------------------------------------------------------------------------------------------------N----GNY-DY----------------ADG------TSISTGKVS----G---------------------------E------------------LAEI----ISNY-----------HLQGD-----------------------------------------------------------------SSK--------------A---------------------RSIL-------LNQ------------------------------------------------------------------------------------------------------------VNYTSDGYKEISTYKALRGY------ 327
 328 -----------------------------QWDIKRVTNSGKSFEL-------NSG-N-HD----------------------------I--VI--------------G--------------------IID---------------------------S--------------GIKK-D------H-------------P---------D--------------------------------LEK--------------NFM--G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GENF-------------------------------------V----PKE---------------------------FNSDKTETGTPNDIEDRV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TY-V-----------------------AGNIA----A---N-------------------------------GR------------AK-----------------------GV--APN-I--GFKSY---RV---FDSE----------K-TT--N------------ATI-------------------------------------V--------SSA--------------I-----------IK---AT--------------------N-----D------G----------V----KV-----------------------------------------INLSMTGYDLKGKC-YWTDPDT-------------GIKHDLGDD--------------------------AAEYELYKRAIGY---------AIKH----KV-----T--------------------------------------------------------------------------------------V---------------VTAAG-NDGLD--CSDT-KKLTEFLNEKNGKYGF---EYEGLTYVV---------------------------------------------------------------------------------------------------------------------------------P-GTI-DG---------------------------V---IN---VS--A------------------------------TGK------------------------TDEI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAY-----S--N--------Y-GK-------------------------------------------------------------------------KFID--V------A-----------------A-----P-------------G-----------------G-------------------------D---FPDLC------------------------------------------------------------------LN-T------------------------------------------------------------------------------------------------------------------GISD----TGY-VF----------------GEG------TSISAPKVS----A---------------------------I------------------AGLI----LCKN-----------P-HLK-----------------------------------------------------------------PKD--------------V---------------------AKII-------YKT-----------------------------------------------------------------------------------------------------SEKLHDNESKEYYGAGLVDAHSA---------- 328
 329 -----------------------------QWDIKRMTNNGKSFQL-------NTG-N-HN----------------------------V--VI--------------A--------------------VLD---------------------------S--------------GIDK-D------H-------------P---------D--------------------------------LKN--------------NLL--G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GENF-------------------------------------I----PKD---------------------------FNNDKTEIGDPRDIEDRL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TC-I-----------------------SGSIA----G---N-------------------------------GR------------IK-----------------------GI--APN-I--GFKSY---RV---FDSR----------G-HT--N------------ATI-------------------------------------M--------SSA--------------I-----------IK---AT--------------------D-----D------G----------A----NV-----------------------------------------INLSMAGYDLKGKC-YWTDPDT-------------GVKHDLGDD--------------------------MAEYELYKRAIQY---------ALNH----NV-----T--------------------------------------------------------------------------------------V---------------VTAAG-NDGLD--CCNT-KSLTEFLNNRDKEDGF---SYEGVTYEI---------------------------------------------------------------------------------------------------------------------------------P-GSI-DG---------------------------V---IN---VS--A------------------------------TGK------------------------NDKI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATY-----S--N--------Y-GK-------------------------------------------------------------------------NFID--V------A-----------------A-----P-------------G-----------------GDHSKT-------E----------SLD---INDMC------------------------------------------------------------------LS-T------------------------------------------------------------------------------------------------------------------AI-E----GQY-RF----------------EVG------TSIAAPKVS----A---------------------------I------------------AGLL----LCKN-----------K-NLT-----------------------------------------------------------------PKE--------------V---------------------AEKI-------YET-----------------------------------------------------------------------------------------------------CDILDNDESKQYYGSGLANAYNAL--------- 329
 330 ----------------------------------------ASYKL-------NGG-TGKG----------------------------A--TV--------------G--------------------VID---------------------------S--------------GIDA-N------H-------------P---------D--------------------------------LIK--------------NYS--G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQNF-------------------------------------V----PA-----------------------------GADETEKGDPADVKDRG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSIA----A---N-------------------------------GK------------IK-----------------------GV--GPD-L--KVRSY---RV---FPES----------G-SA--P------------TAW-------------------------------------I--------VDA--------------I-----------VA---AA--------------------N-----D------N----------V----DV-----------------------------------------INMSIGGFD-SMKY-Y----DN-------------GKKY---SD--------------------------NADVLIWKRAIQY---------AVQK----NV-----T--------------------------------------------------------------------------------------V---------------VAASG-NESLN--MNDK-KMITDYLNKEYGSDDL---IFKGPYVET---------------------------------------------------------------------------------------------------------------------------------P-GQI-PG---------------------------V---IN---VS--S------------------------------SNQWS----------------------TDKI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AFY-----S--N--------Y-GN-------------------------------------------------------------------------SFID--V------A-----------------A-----P-------------G-----------------GDNGPVYAETGDLA----------QRD---FHYRT------------------------------------------------------------------LS-TWP---------------------------------------------------------------------------------------------------------TYLEPYFTSDL----HNY-AL----------------MHG------TSMASPKVA----G---------------------------I------------------AGVI----KAAH-----------P-TYS-----------------------------------------------------------------PAQ--------------V---------------------ENLI-------KQT-----------------------------------------------------------------------------------------------------AKDFGKPGHDALFGSGEANIYNA---------- 330
 331 ---------------------------KFNWPYARITNNQMKFNQ-------FKG-E-RS----------------------------V--EI--------------A--------------------LID---------------------------S--------------GLDT-T------H-------------P---------L--------------------------------FQY--------------NVK--P-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKTF-------------------------------------V----ESS--------------------------------------SSTSDDF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-V-----------------------AGVV--------------------------------------------------------R-----------------------TI--APQ-A--TLVPY---KV---LGK-----------Q-GG--E------------SIW-------------------------------------T--------LKA--------------M-----------VE---AV--------------------N-----D------G----------V----DI-----------------------------------------LNISLGTYKSDNIE----------------------------DE--------------------------KVTRLAYERAVEY---------AKKH----KV-----V--------------------------------------------------------------------------------------V---------------VASSG-NEGHD--L--------DEQV-----------AAGN--YHL---------------------------------------------------------------------------------------------------------------------------------P-GGL-PE---------------------------V---LT---VG--S------------------------------TTK------------------------DRDR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYY-----S--N--------Y-GS-------------------------------------------------------------------------N-VD--I------V-----------------A-----P-------------G-----------------GD------FGPMYS----------TKGEMNVTYML------------------------------------------------------------------MT-TAP---------------------------------------------------------------------------------------------------------MKQQQNFIDQAVGLPQGY-TL----------------SFG------TSLSAPQVS----A---------------------------T------------------LALM----MA---QD-------KAKKPN-----------------------------------------------------------------PNK--------------Y---------------------INQL-------LKE-----------------------------------------------------------------------------------------------------AMDLGKPGFDPVYGYGELKIPSSLK-------- 331
 332 -----------------NINILNKDFKSFNWPYKKILSHIDPVKE-------QLG---KD----------------------------I--TI--------------A--------------------LID---------------------------S--------------GIDR-L------H-------------P---------N--------------------------------LQD--------------NNL--R-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKNH-------------------------------------V------N--------------------------------------DIELDEY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-V-----------------------AGVI--------------------------------------------------------D-----------------------TI--APR-V--NLNSY---KV---MDG-----------T-DG--N------------SIN-------------------------------------M--------LKA--------------I-----------VD---AT--------------------N-----D------Q----------V----DI-----------------------------------------INVSLGSYKNMEID----------------------------DE--------------------------RFTVEAFRKAVNY---------ARKN----NI-----L--------------------------------------------------------------------------------------I---------------VASAG-NESRD--ISTGNEK------------------------HI---------------------------------------------------------------------------------------------------------------------------------P-GGL-ES---------------------------V---IT---VG--A------------------------------TKK------------------------SGDI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADY-----S--N--------Y-GS-------------------------------------------------------------------------N-VS--I------Y-----------------G-----P-------------A-----------------GG------YGDNYK----------ITGQIDAREMM------------------------------------------------------------------MT-YYP---------------------------------------------------------------------------------------------------------TSL-VSPLGKAADFPDGY-TL----------------SFG------TSLATPEVS----A---------------------------A------------------LAAI----MS---KN-------VDNSKD-----------------------------------------------------------------SNE--------------V---------------------LNTL-------FEN-----------------------------------------------------------------------------------------------------ADSF--IDKNSMLKYKEVRIK------------ 332
 333 -----------------------------------------------------HL-K-DT----------------------------V--TI--------------G--------------------IID---------------------------S--------------GIDI-T------N-------------P---------Y--------------------------------LKD--------------KIV--Q-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GRSF-------------------------------------V-----SS--------------------------------------AYTKDDT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-I-----------------------FGIL--------------------------------------------------------D-----------------------NL--IKG-A--NYKFY---KV---MDN-----------E-IT--N------------SLN-------------------------------------L--------VKA--------------I-----------IA---AV--------------------D-----D------G----------V----DI-----------------------------------------INISLGIYKNSQTE----------------------------SD--------------------------QIIINSFKKAINY---------ARNN----NV-----L--------------------------------------------------------------------------------------I---------------VASAG-NNGLN--MDEY-----------------------PHIIHL---------------------------------------------------------------------------------------------------------------------------------P-SDL-EY---------------------------V---IN---VG--S------------------------------SDK------------------------HNDL-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSY-----T--N--------Y-GK-------------------------------------------------------------------------N-VN--I------I-----------------A-----P-------------S-----------------GE------W---IA----------KDDKILFSEMI------------------------------------------------------------------IT-YGK---------------------------------------------------------------------------------------------------------ESSFLKNNPNYNGIPKGL-VL----------------SYG------TSLAPPQVA----A---------------------------A------------------FAVV----IDKY------------KNLS-----------------------------------------------------------------IDE--------------Y---------------------KSIV-------FEN-----------------------------------------------------------------------------------------------------SSEISHNT------------------------- 333
 334 ------------------RRLLRAV-P-----KQIVSALQAEILW-------NMG-FTGA--------------------------G-V--KV--------------A--------------------IFD---------------------------T--------------GLS-EN------H-------------P---------H--------------------------------FKKGRIK----------DRTNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASY------------------------------------------------------------KDCL--------GF--APD-A--DIHVY---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--NV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------KV-----I--------------------------------------------------------------------------------------M---------------ISAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-IARF-----S--S--------R-GMT-TWELPHGYGRLKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SA--------------------------------V------------------------------------------------------------------RGSALKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LYS----AV--LDRANI-IN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------MAS-------------------------------------------------------------------------------------ARRLPEV-----------------NMFEQGHGKLDLIRAYQ-------- 334
 335 --------------RFKGRRLLRAV-P-----KQIVSALQAEILW-------NMG-FTGA--------------------------G-V--KV--------------A--------------------IFD---------------------------T--------------GLS-EN------H-------------P---------H--------------------------------FKKGRIK----------DRTNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASY------------------------------------------------------------KDCL--------GF--APD-A--DIHVY---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--NV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------KV-----I--------------------------------------------------------------------------------------M---------------ISAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-IARF-----S--S--------R-GMT-TWELPHGYGRLKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SA--------------------------------V------------------------------------------------------------------RGSALKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LYS----AV--LDRANI-IN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------MAS-------------------------------------------------------------------------------------ARRLPEV-----------------NMFEQGHGKLDLIRAYQ-------- 335
 336 --------------RHKSRRLLRSVSS-----KQITSALQAESLW-------QMG-FTGQ--------------------------G-I--KI--------------A--------------------IFD---------------------------T--------------GLA-EE------H-------------P---------H--------------------------------FKKGRIK----------DRTNW----TNEKTLE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVV-----ASS------------------------------------------------------------KDCL--------GF--APD-A--DLYIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------RRV--NV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------GV-----V--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SS--------------------------------V------------------------------------------------------------------RGSALKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LMS----AV--MPTGAA-VN-----------------------------------------------------------------PAS--------------V---------------------KQAL-------MAS-------------------------------------------------------------------------------------ARRLPNI-----------------NMFEQGQGKLDLLKAYQ-------- 336
 337 --------------RYTSRRLLKAI-P-----RQITNALQADILW-------EMG-YTGA--------------------------G-I--KV--------------A--------------------VFD---------------------------T--------------GLN-EN------H-------------P---------H--------------------------------FKK--IK----------ERTNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASH------------------------------------------------------------KECL--------GF--SPD-A--DLFIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--NV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------KV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SA--------------------------------V------------------------------------------------------------------RGSGIKS---GCRT--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVSL----LAS----AV--LQRLHV-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------MAS-------------------------------------------------------------------------------------ARRLPAV-----------------NMFEQGHGKLDLVRAYQ-------- 337
 338 --------------RHTSRRLLRTV-P-----RQVTHVLQADLLW-------AMG-FAGS--------------------------G-I--KV--------------A--------------------VFD---------------------------T--------------GLS-EN------H-------------P---------H--------------------------------FRN--LK----------DRTNW----TNEKTLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASS------------------------------------------------------------KECQ--------GF--SPD-A--DLHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--NV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------KV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------RGSGLKS---GCRT--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LAS----AV--IHRIPM-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------MAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLKAYQ-------- 338
 339 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-FTGA--------------------------G-V--KV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-S--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------RGSGMKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EM-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 339
 340 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------G-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APN-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------RGSGMKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EM-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 340
 341 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKV--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 341
 342 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 342
 343 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKM--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 343
 344 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRMKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 344
 345 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKM--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------V---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 345
 346 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGA--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------V---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 346
 347 --------------RHSSRRLLRAI-P-----RQVAQTLQADVLW-------QMG-YTGT--------------------------N-V--RV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNERTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AG--------------------------------V------------------------------------------------------------------RGSGVKG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LVS----TV--QKR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 347
 348 --------------RHSSRRLLRAI-P-----RHVAQILQADVLW-------QMG-HTGS--------------------------G-V--KV--------------A--------------------VFD---------------------------T--------------GLS-EK------H-------------P---------H--------------------------------FKN--VK----------ERTNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASM------------------------------------------------------------RECQ--------GF--APD-S--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-HPFVDKV-------------WELTA---N--------------------------------------------------------KV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------RGSGLKE---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AVTL----LAS----TV--LNR-EL-VN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLLRAYQ-------- 348
 349 -----------------SRRLLRAI-P-----RQITSVLQADALW-------NMG-FTGA--------------------------G-V--KV--------------A--------------------VFD---------------------------T--------------GLA-KS------H-------------P---------H--------------------------------FRK--IR----------ERSNW----TNEKTFE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGLI-----ASS------------------------------------------------------------KQCL--------GF--APD-S--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--DV-----------------------------------------LNLSIGG--PDFMD-QPFIDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-IARF-----S--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SA--------------------------------V------------------------------------------------------------------RGSSIQG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AITL----LAS----GV--IQSGGV-VN-----------------------------------------------------------------PAS--------------V---------------------KQSL-------MAS-------------------------------------------------------------------------------------ARRLPGV-----------------NMFEQGHGKLDLVRAY--------- 349
 350 ------------------RRLLRAI-P-----RQITSALHANVLW-------TLG-HTGK--------------------------N-I--KV--------------A--------------------VFD---------------------------T--------------GLA-GN------H-------------P---------H--------------------------------FRH--IS----------DRTDW----TDEKTME----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASS------------------------------------------------------------SECL--------GF--APD-S--ELFIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KRI--DV-----------------------------------------LNLSIGG--PDFLD-QPFIEKV-------------WELTS---N--------------------------------------------------------GV-----I--------------------------------------------------------------------------------------M---------------ISAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DMMD---------------------------V---IG---VGGID------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-LAPF-----S--S--------R-GMT-TWELPQGYGRVKP----------------------------------------------------------D-----I------I-----------------T-----Y-------------S-----------------SG--------------------------------V------------------------------------------------------------------RGSALHS---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVT----G----------------------------------------------AVAL----LAS----AV--DKSK---VN-----------------------------------------------------------------PAS--------------M---------------------KQSL-------MAT-------------------------------------------------------------------------------------AQRIPGA-----------------NMFEQGMGKLDLVRAY--------- 350
 351 --------------------------------------------------------FTGT--------------------------G-I--AV--------------A--------------------VFD---------------------------T--------------GLA-KD------H-------------P---------H--------------------------------FRK--VK----------DRSNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASS------------------------------------------------------------KDCL--------GF--APD-A--DLHIY---KV---FTSK----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NH--AIQ--------------------------------------------KRI--KI-----------------------------------------LNLSIGG--PDFMD-RPFVDKV-------------WELTA---N--------------------------------------------------------GV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGID------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IAKF-----S--S--------R-GMT-TWELPSGYGRVKP----------------------------------------------------------D-----I------V-----------------A-----Y-------------G-----------------SN--------------------------------V------------------------------------------------------------------QGSSLNG---RCRV--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------AITL----LAS----SV--AHF-DI-VN-----------------------------------------------------------------PAS--------------I---------------------KQAL-------LHS-------------------------------------------------------------------------------------AIKLPNV-----------------NIFEQGHGKMDL------------- 351
 352 -----------------SRKILRAI-P-----RQISHVLQANVLW-------GLG-HRGK--------------------------G-V--KV--------------A--------------------VFD---------------------------T--------------GLP-KS------H-------------P---------H--------------------------------FKN--IK----------DRTDW----TEEKTVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DEV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVI-----ASD------------------------------------------------------------RECY--------GF--APE-A--DLYIF---RV---FTNK----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KNI--DI-----------------------------------------LNLSIGG--PDFMD-KPFVDKV-------------WELTA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGIN------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-IASF-----S--S--------R-GMT-THELPYGYGRIKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------AS--------------------------------V------------------------------------------------------------------TGSSLKG---GCRS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------ALAL----LLS----SV--ASKNVV-TN-----------------------------------------------------------------PAS--------------V---------------------KQAI-------IES-------------------------------------------------------------------------------------ATRIPDA-----------------NMFEQGHGKFDLIKAYK-------- 352
 353 --------------RHTNRRLLRAI-P-----RQITALLKADVLW-------SMG-ITGQ--------------------------G-V--KV--------------A--------------------VFD---------------------------T--------------GLA-KS------H-------------P---------H--------------------------------FKR--IK----------ERTNW----TNEKTLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------AGII-----ASS------------------------------------------------------------KECF--------GF--APD-A--ELHIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------KKI--NV-----------------------------------------LNLSIGG--PDFLD-QPFVDKV-------------LELSA---N--------------------------------------------------------RV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PG--DQMD---------------------------V---IG---VGGMD------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IAKF-----S--S--------R-GMT-TWELPYGYGRLKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SQ--------------------------------V------------------------------------------------------------------KGSNLNG---GCKS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPMVA----G----------------------------------------------AVTL----IAS----GV--LDRPGVDLN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------IEG-------------------------------------------------------------------------------------AERLADN-----------------NMFEQGHGKLNILRSMK-------- 353
 354 ---------------------------------QIAEAVQAKQMW-------EAG-FKGQ--------------------------G-V--KV--------------A--------------------IFD---------------------------T--------------GLP-AK------H-------------P---------H--------------------------------FKN--VI----------ERSDW----TDEETSD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGMIG----GSS------------------------------------------------------------SDCP--------GL--APE-S--ELYIF---RV---FTNN----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIL--------------------------------------------RKI--NV-----------------------------------------LNLSIGG--PDFMD-KPFVEKV-------------WELTA---N--------------------------------------------------------HV-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---IG---VGGVD------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-IARF-----S--S--------R-GMT-TWELPAGYGRIKP----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------LN--------------------------------V------------------------------------------------------------------YASDLTG---GCRA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVT----G----------------------------------------------AVAL----LLS----SV--KKNQRDLIN-----------------------------------------------------------------PGS--------------I---------------------KQCL-------LAS-------------------------------------------------------------------------------------ADRLPSA-----------------NIFEQGVGKLNLVEAYK-------- 354
 355 --------------------VLRNRNPNNDRHRQLCSVLHANILW-------KLG-ITGK--------------------------G-V--KV--------------A--------------------IFD---------------------------T--------------GLT-KN------H-------------P---------H--------------------------------FRN--VK----------ERTNW----TNEKSLD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------AGVI-----ASS------------------------------------------------------------RECL--------GF--APD-A--DLYIF---KV---FTNS----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIY--------------------------------------------RKI--NI-----------------------------------------LNLSIGG--PDFMD-SPFVEKV-------------LELSA---N--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------M---------------ISAAG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PG--DQSD---------------------------V---VG---VGGIQ------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-IAKF-----S--S--------R-GMT-TWELPLGYGRMGL----------------------------------------------------------D-----I------V-----------------T-----Y-------------G-----------------SQ--------------------------------V------------------------------------------------------------------EGSDVRK---GCRR--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVSSPVVA----G----------------------------------------------AAAL----LIS----GA--FQKIDY-IN-----------------------------------------------------------------PAS--------------L---------------------KQVL-------IEG-------------------------------------------------------------------------------------AEKLPHY-----------------NMFEQGAGKLNLLKSMQ-------- 355
 356 -------------------------------------------LW-------SEG-YSGK--------------------------G-V--KV--------------A--------------------IFD---------------------------T--------------GLS-KD------H-------------P---------H--------------------------------FKN--IV----------EITDW----TREENSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGIIA----SGS------------------------------------------------------------EKCL--------GF--APD-S--DIHIY---RV---FNSQ----------K-ES--F------------TSW-------------------------------------F--------IDA--------------F-----------NH--AIL--------------------------------------------TKM--DV-----------------------------------------LNLSIGG--PDFMD-RPFVEKV-------------WEMSA---N--------------------------------------------------------NI-----I--------------------------------------------------------------------------------------V---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQSD---------------------------V---IG---VGGID------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-LASF-----S--S--------R-GMT-TWEIPEGYGRVKP----------------------------------------------------------D-----L------V-----------------A-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------YGSSFRG--DACKP--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVSSPVVA----G----------------------------------------------AISL----LIS----SA---KDKSI-IN-----------------------------------------------------------------PAS--------------M---------------------KQIL-------IES-------------------------------------------------------------------------------------ADRIKGA-----------------GLFEQGGGKLNIMAA---------- 356
 357 ------------------RKLKSINDH-----IQITDLFNVRKLW-------NQG-FTGR--------------------------G-T--KV--------------A--------------------VFD---------------------------T--------------GLA-KD------H-------------P---------H--------------------------------FSN--VV----------EITDW----AREKVENKK-KSNT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------TGIIA----SSS------------------------------------------------------------EKCM--------GF--APD-A--EIYIY---RV---FNSE----------K-VS--F------------TSW-------------------------------------F--------IDA--------------F-----------NH--VIL--------------------------------------------TKV--DV-----------------------------------------LNLSIGG--PDFMD-KPFVEKV-------------WEVSA---N--------------------------------------------------------KI-----I--------------------------------------------------------------------------------------V---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQSD---------------------------V---IG---VGGID------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-LASF-----S--S--------R-GMT-TWELPHGYGRVKP----------------------------------------------------------D-----I------V-----------------A-----Y-------------G-----------------SG--------------------------------V------------------------------------------------------------------YGSPLNGHDDNCKA--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVSSPVVS----G----------------------------------------------AIAL----LIS----TV---KDKSI-IN-----------------------------------------------------------------PSS--------------M---------------------KQVL-------IES-------------------------------------------------------------------------------------AEKIKNA-----------------GIFEQGNGKLNVLGA---------- 357
 358 ----------------SWRRKLHMQ-K-----SHVTSLFGAERLW-------GRG-FTGK--------------------------K-V--KM--------------A--------------------IFD---------------------------T--------------GIR-AD------H-------------P---------H--------------------------------FRN--IK----------ERTNW----TNEDTLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVIA----GQD------------------------------------------------------------AECP--------GF--APD-T--EIYAF---RV---FTDA----------Q-IS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIA--------------------------------------------TGM--DV-----------------------------------------LNLSIGG--PDYLD-LPFVEKV-------------WELTA---N--------------------------------------------------------NI-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQSD---------------------------V---IG---VGGID------------------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-IASF-----S--S--------R-GMT-TWELPHGYGRVKP----------------------------------------------------------D-----V------V-----------------A-----Y-------------S-----------------RD--------------------------------I------------------------------------------------------------------MGSKIST---GCKT--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------VVCL----LVS----VIPEDKRKSI-LN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------VEG-------------------------------------------------------------------------------------ASKLLGP-----------------NIYEQGAGKLDLWQSYE-------- 358
 359 --------------TLNWSRHLLAQ-K-----TQVTSMFGADHLW-------KKG-YTGA--------------------------K-V--KM--------------A--------------------IFD---------------------------T--------------GIR-AD------H-------------P---------H--------------------------------FRK--IK----------ERTNW----TNEDTLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVIA----GRN------------------------------------------------------------PECL--------GF--ASD-T--EIYAF---RV---FTDA----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIA--------------------------------------------TDM--DV-----------------------------------------LNLSIGG--PDYLD-LPFVEKV-------------WEITA---S--------------------------------------------------------NI-----I--------------------------------------------------------------------------------------M---------------VSAIG-ND--------GPLYGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQSD---------------------------V---IG---VGGID------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-IASF-----S--S--------R-GMS-TWELPHGYGRVKP----------------------------------------------------------D-----V------V-----------------A-----Y-------------G-----------------RD--------------------------------I------------------------------------------------------------------MGSKIST---GCKS--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPVVA----G----------------------------------------------IVCL----LVS----VIPESRRKDL-LN-----------------------------------------------------------------PAS--------------M---------------------KQAL-------VEG-------------------------------------------------------------------------------------AAKLSGP-----------------NMYEQGAGRVDLLESYE-------- 359
 360 ---------------------------------------------------------TGK--------------------------G-I--RV--------------A--------------------IFD---------------------------T--------------GLEAGG------H-------------D------------------------------------------FDN--VV----------EQINW----TNEPTLK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGVIG----GRD------------------------------------------------------------QGCS--------GF--APD-A--DLYIF---RV---FSGE----------Q-VS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--ALF--------------------------------------------LGV--DI-----------------------------------------VNLSIGG--PDFKD-QPFVDKV-------------RELSA---N--------------------------------------------------------GV-----V--------------------------------------------------------------------------------------V---------------FSAVG-ND--------GPLYGTQHN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------T---IG---VGAVS------------------------------A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RGVASF-----Q--S--------R-GMT-TWELPGGYGRVKP----------------------------------------------------------D-----L------V-----------------A-----V-------------G-----------------QF--------------------------------V------------------------------------------------------------------LGPKAGGPLGQCSG--------------------------------------------------------------------------------------------------------------------------------------ISG------TSVACPVVA----G----------------------------------------------AAAL----LAS----TVPPDRRRDI-VN-----------------------------------------------------------------PAS--------------I---------------------KQVL-------TES-------------------------------------------------------------------------------------ARRVKEA-----------------GVFEQGAGALDVAAAF--------- 360
 361 --------------------------------KQPWKLLQAEYAW-------SRG-LCGN--------------------------G-V--RV--------------G--------------------IFD---------------------------T--------------GLAPSD------H-------------K---------H--------------------------------FSLSNII----------ERTDWTVDITNRSYSDDS-IEAL---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TY-V-----------------------TGLIA----AQNPN-------------------------------LY------------YSKFIHSFNKHDDSTCPPW------GF--APR-A--DLFIF---RV---FTDT----------Q-IS--Y------------TSW-------------------------------------F--------LDA--------------F-----------NY--AIS--------------------------------------------RKL--HV-----------------------------------------INLSIGG--PDFLD-KPFVDKV-------------LELSA---N--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------L---------------VSAIG-ND--------GPLFGTLNN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQMD---------------------------V---LG---VGGVD------------------------------A--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-VARF-----S--S--------R-GMT-GWELPAGYGRVKP----------------------------------------------------------D-----I------V-----------------T-----F-------------S-----------------TG--------------------------------V------------------------------------------------------------------ISSNLDG---KCRV--------------------------------------------------------------------------------------------------------------------------------------LSG------TSVASPIVT----G----------------------------------------------VVSL----LINLYHMNI--DNYPFVPVN-----------------------------------------------------------------PIS--------------I---------------------KQAL-------IAS-------------------------------------------------------------------------------------ANQLNSVRVFGTNSIKWLQETDQSSMFEQGAGLVNLQSALE-------- 361
 362 -------------------------------------------LW-------ERG-FKGQ--------------------------G-V--KV--------------G--------------------VFD---------------------------T--------------GLS-----------------------S---------K--------------------------------LTN--VK----------EKINW----THEPKNT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DTV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------ASVIS----GTD------------------------------------------------------------ARCP--------GI--APE-A--ELFVF---RM---FTGE----------Q-LS--F------------TSW-------------------------------------Y--------LDA--------------F-----------NY--ALF--------------------------------------------KGI--HV-----------------------------------------LNLSTGG--PDFQD-LPFVDKV-------------KELAA---H--------------------------------------------------------GV-----I--------------------------------------------------------------------------------------L---------------VSAVG-ND--------GPHYGLLSN------------------------------------------------------------------------------------------------------------------------------------------------------PA--DQIE---------------------------V---IG---VGGVT------------------------------K--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-IAEF-----S--S--------R-GMT-TWELPFGSGRVKP----------------------------------------------------------D-----I------V-----------------T-----L-------------A-----------------ED--------------------------------V------------------------------------------------------------------PGADASG---GCKM--------------------------------------------------------------------------------------------------------------------------------------LSG------TSASAPIVS----A----------------------------------------------SIAV----LAS----IIPAEERRNL-LN-----------------------------------------------------------------PAS--------------I---------------------KQIL-------LES-------------------------------------------------------------------------------------ADKLAAR--------HDSEYVVRNHIFEQGNGALNISKAS--------- 362
 363 IGAPAAW---------------------------------------------AAG-FKGQ--------------------------N-I--RI--------------G--------------------HLD---------------------------S--------------GIDP-S------H-------------P---------E--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGKVAAFQ--EF-NGEGDRVSSQPHD------------TT-----------------------------------------------------------------------------------------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TH-T-----------------------AGLLV----GSK-------------------------------------------------------------------------VGVAPG-A--KVISA---LV---LPNN------------EG--T------------FAQ-------------------------------------V--------IAG--------------M-----------QY---VL------------DPDNNADTD-----D------G----------A----DV-----------------------------------------VNMSLG-------I-PGT---W---------------------N--------------------------EFIV-----PVNN-M--------LKA----GV-----V--------------------------------------------------------------------------------------P---------------VFAIG-NF--------GP---------------AAGSTGS---------------------------------------------------------------------------------------------------------------------------------------P-G--N-L----PQ---------------------A---IG---VG--A------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NG-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-ASF-----S--S--------R-G------------------------PVAWQGEISGVFT---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSTVRNG--------GY-QA----------------MSG------SSQASPITA----G---------------------------A------------------VA-V----LL----S-------AKPGAS-----------------------------------------------------------------VDA--------------I---------------------KNAL-------FTS-------------------------AS------------------------------------------------------------------------NASAKNNNVGFGQISIPGALG-------------- 363
 364 -----------------------RPAFGSCT---------------------APG-TPAG--------------------------CKV--IV-----------------------------------SID---------------------------T--------------A-----------S-------------P---------D--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-----------------------LDDP-----------------------------------------------------------------------------------------D-------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TG-V-----------------------SAIVL----G---------------------------------------------------------------------------V--APD-T--RIIAI---DV---FDGEY------------A--Y------------DAD-------------------------------------I--------IEA--------------A-----------NW---AI----------------ANRAT-----Y------N----------IV----A-----------------------------------------INMSLGAGSFTSPC-TDTTYNT---------------------------------------------------------LVSQ---------VRAA----GI-----M--------------------------------------------------------------------------------------P---------------VAASG-NE--------GL---------TNALIA----------------------------------------------------------------------------------------------------------------------------------------------P-ACIP-----G-----------------------V---IS---VG--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSYFHG---TCLDPMVPDKV-ACF-----S--N------------------SASFL--------------------------------------------------------------T-----L------L-----------------A-----P-------------G-----------------AY--------------------------------I------------------------------------------------------------------TA------------------------------------------------------------------------------------------------------------------------AGELT----------------------AG------TSEATPHVS----G---------------------------A------------------VA-V----LR----S-------AFPAES-----------------------------------------------------------------LDA--------------I---------------------QARL-------TSTGKPVTDSRNGVTKPRINVAAAIGPPANDLFSAAQALPATAGQTTGVNLNATRETGEPDHAGVAGGASVWWTWQGQTSGIVSLDTHGSSFDTLLAVYTGTSVGNLTPAAANDNDGGVGGTSGLTFTALAGEVYRI 364
 365 --------------------------------WGDNALKVEQLRA-------S-N-YTGA--------------------------G-V--AV--------------C--------------------IGD---------------------------T--------------GIDG-N------H-------------P---------E--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QKKIKG------------FK-NFTA--DLNRN-DP-------------------------------------------------------------------------------------YQLND---V---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TH-V-----------------------AGTVF----A-QYG-------------------------------AG------------TGASGLQSGMDANGVG---------GV--ASG-V--NLYMA---RV---LGDD----------G-SG--S------------SSG-------------------------------------I--------ING--------------V-----------NW---CA-------AQLKSQGG------------------T----------ESK--VV-----------------------------------------ISLSLG-G-----G-RAS-------------------------Q--------------------------TEQR-----AYTS---------VYNK----GV-----L--------------------------------------------------------------------------------------T---------------VAATG-N------------------D-----GA---AVSY---------------------------------------------------------------------------------------------------------------------------------------P-AAYT-N---------------------------V---VG---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------SA-------E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AR-ASF-----S--N--------F-G---SQV-------GKL-----------------------------------------------------------------------------------------------P-------------T-----------------TG--------------------------------T------------------------------------------------------------------VA-VTG-----------------------------------------------------------------------------------------------A-------------------------DY-DF----------------FDG------TSMATPHVS----A---------------------------A------------------AA-V----VW----A-------AKPTLT--NTQ-----------------------------------------------------------------------------L---------------------LNLL-------TST-------------------------AKDLGAAGK-----------------------------------------------------D-----------------------NDFGSGLVNPLKA---------- 365
 366 ---------------------VDPPRYLLRETTPWGYGAVGAHLL-------DDF-NAGN----------------------------R--TV--------------C--------------------IID---------------------------S--------------GYDL-S------H-------------N---------D--------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGNRVNGTNDSGTGSWS-------------------------------------------------------------------------------------------------------DPGNN---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TH-V-----------------------AGTIA----AIANN-------------------------------EG------------VK-----------------------GI--MPN-HNVNLHIV---NV---FNEA----------G-WG--Y------------SSG-------------------------------------L--------VKA--------------I-----------QT---CA--------------------D-----N------G----------A----NV-----------------------------------------VNMSLG---------GSQSSTE--------------------EN--------------------------ALKT------------------IYDQ----GV-----L--------------------------------------------------------------------------------------L---------------IAAAG-ND--------GN---------T--------AHSY---------------------------------------------------------------------------------------------------------------------------------------P-ASYD-S---------------------------V---MS---AA--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------ND-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-AAF-----S--Q-----------------------------------AT------------------------------------------------NQVE--I------A-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------TTVTVSSITLVSQFDRVVPHNRLVHNGTQLAPVAGPITATLASYTGGNNCGDMSGKICLTEGNQGSAYPEVDAVKACYNAGASAADSNWALPGLQNPFLVDANMVYRMVSMTVRAFGLELQYGVGQEMV-AT----------------TTGEDYEYYTSMATPHVT--------------------------------V------------------AG-L----VW----S-------FHPTTA------------------------------------------------------------------AQ--------------V---------------------RNAL-------IKT-------------------------------------------------------------------------------------------------------------ATDIDVAGRDNRTGYGLNADAA--- 366
 367 P----------YGIRMVQADQLSDVY--------------------------------AA--------------------------N-R--KV--------------C--------------------VID---------------------------S--------------GYLR-N------H-------------V---------D--------------------------------L---------------------P----------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--G---VTGSTFSGHGSWFTDGNG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TH-V-----------------------AGTIV----AL--D-------------------------------NN------------VGVVGVLP-SGLV------------GLH-----------NV---KI---FNDS----------GVWT--R------------ASD-------------------------------------L--------IQA--------------I-----------QS---CQ-----SAG------------------------------------S----HV-----------------------------------------VNMSLGGSQG--SV-TEQ-------------------------N--------------------------AMRN-----FYQQ-----------------GM-----L--------------------------------------------------------------------------------------L---------------VAAAG-NS--------GN---------S--------GFSY---------------------------------------------------------------------------------------------------------------------------------------P-A----S----YDA--------------------V---IS---VA--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SG-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-ANF-----S--Q--------F-N---S--------------------QV------------------------------------------------E-----L------S-----------------A-----P-------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNVLSTG-----NNG--------GY-LS----------------YSG------TSMASPHVA----G---------------------------V------------------AA-L----VW----S-------HFPQCR-----------------------------------------------------------------PER--------------I---------------------RQSL-------SQT-------------------------AL------------------------------------------------------------------------DRGAAGRDNFYG-------WGIVQASAAYN----- 367
 368 -------------------------LPWGLAAIQANSKKIPLPSP-------SSD-C-------------------------------F--KI--------------C--------------------IVD---------------------------S--------------GLLV-E------H-------------P---------D--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PYTRGATNIAGEEFNIGALSKWDEPIAI-------------------------------------------------------------------------------------------------------------------A--------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TH-V-----------------------TGTML----ATGTR-------------------------------NP------------RVV----------------------GV--IPN-N--QNICLLVARV---FGDE----------VNPG--A------------STS-T-----------------------------------T--------DRA--------------A-----------EW---CG--------------------D-----M------G----------A----KV-----------------------------------------INLSFG---------SPTFSTN--------------------SA--------------------------AIYR-----SL------------RSE----GV-----L--------------------------------------------------------------------------------------L---------------VSSAG-NA--------QD--------------NSKS---Y---------------------------------------------------------------------------------------------------------------------------------------P-ASYS-D---------------------------V---IS---VS--S------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------KD-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QR-FWT-----S--Q--------H-N--------------------------------------------------------------------------DQVD--L------A-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------VS-TVPGMGLFDELGREYSTALIDYSPFITSPLTAGVVQCGLGTEPCKDAEGRICLIQVGSNAIDDKAFHCEMGGGVAAVIYNTQFTTAPTRGAINSFVSIPVMGVSYADGLALLSKESITVDLQVPSY-TE----------------KRG------TSMAAPHVA----G---------------------------V------------------AAKI----WA------------ARPACS-----------------------------------------------------------------NNQ--------------V---------------------RDAL-------EAT-----------------------------------------------------------------------------------------------------AKDLGDPGRDDMYGHGLIQ-------------- 368
 369 -------------------------------------------------------------WGLDLSRLDETQELINEHQVMSTR-------I--------------C--------------------VID---------------------------S--------------GIDY-N------H-------------P---------D--------------------------------LKDNIEL--NLKELHGRKGFDDDN--NGIVDDIYG------ANFVNNSGNPMDDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TH-V-----------------------SGIIS----AIGNN-----------------------------------------------------------------NIGVVGVDVNSK----LII----CKA-------------------LD---------------EH-------------------------------KLGRLGDM--------FKCLDYCISRN------A-------------------------------------------------------------------HM-----------------------------------------INGSF-------SFDEYSGIFN-------------SSVEYLQRK--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------F---------------FVSAS-NCSHP--KS----------------------------------------------------------------------------------------------------------------------------------------------------------------STPDIRKCDLSINAKYP---------PILSTVYDNV---IS---VANLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KND-----------------------------------------------------------NNNH-----------------------YSLSINSFY-----S-----------N----------------------------------------------------------------------------------------------------------------------KYCQLAAPGTNIYSTA----------P---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HNSYRKLNG------TSMAAPHVA----A---------------------------I------------------ASLI----FS-----------------------------------------------------------------------------------INPD-------LSYKKV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 369
 370 -----------------------------------------------PGKYHFNDEFRNLQWGLDLSRLDETQELINEHQVMSTR-------I--------------C--------------------VID---------------------------S--------------GIDY-N------H-------------P---------D--------------------------------LKDNIEL--NLKELHGRKGFDDDN--NGIVDDIYG------ANFVNNSGNPMDDN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TH-V-----------------------SGIIS----AIGNN-----------------------------------------------------------------NIGVVGVDVNSK----LII----CKA-------------------LD---------------EH-------------------------------KLGRLGDM--------FKCLDYCISRN------A-------------------------------------------------------------------HM-----------------------------------------INGSF-------SFDEYSGIFN-------------SSVEYLQRK--------------------------------------------------------GI-----L--------------------------------------------------------------------------------------F---------------FVSAS-NCSHP--KS----------------------------------------------------------------------------------------------------------------------------------------------------------------STPDIRKCDLSINAKYP---------PILSTVYDNV---IS---VANLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KND-----------------------------------------------------------NNNH-----------------------YSLSINSFY-----S-----------N----------------------------------------------------------------------------------------------------------------------KYCQLAAPGTNIYSTA----------P---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HNSYRKLNG------TSMAAPHVA----A---------------------------I------------------ASLI----FS-----------------------------------------------------------------------------------INPD-------LSYKKVI------------------QILKDSI-------VYLPSLKNMVAWAGYADINKAVNLAIKSKKTYINSNISNKWKKKSRYLH---------------------------------------------------------------------------------------- 370
 371 -------------------------------GTIVEPDHLVQSVNTSSKG--SNDPLLDRLWGMDALNVKGAWDIITTGEPNMGSRRPL---V--------------C--------------------VLD---------------------------T--------------GIDY-N------H-------------P---------D--------------------------------LRDNMEV--NQAERDGTPGVDDDN--NGEVDDIYG------ANMLSKENDPADDH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------AGTIG----AHGNN-----------------------------------------------------------------GIGVAGVAWAPR----LLP----CKF-------------------LA---------------YT-------------------------------GRGYSSDA--------VRCIDYCVKRG------A-------------------------------------------------------------------DI-----------------------------------------VNHSWG------GSWPSEALRE-------------AVVR-TANN--------------------------------------------------------GL-----I--------------------------------------------------------------------------------------H---------------IFAAG-N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGVDIDQRAFYP---------AAFSTEADGL---IT---VANVK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GDPDHG---GKRI-IELDRSSNY-----G-----------I----------------------------------------------------------------------------------------------------------------------QRVQVACPG-----MWILSTVPTSGSS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQPYAEKSG------TSMAAPALS----G---------------------------I------------------VALM----LA-----------------------------------------------------------------------------------VNPG-------LSTRQVR------------------EGLRQCS-------VQQPLLQGKVEWGSMPDAKR--------------------------------------------------------------------------------------------------------------------- 371
 372 -------------------------------------------------------------------------------------------VV--------------G--------------------VID---------------------------T--------------GVDY-S------H-------------P---------D--------------------------------L---------------------A----------------ANAWV-----------------NSG-----------------------------EIA----------------------------------------------------------------------------------------------------------------------------------GDGIDNDGNGYIDDVHGINAITDVGD------------PM-----------------------------------------------------------------------------------------D---D---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTIG----ASG-N-------------------------------NG------------VGV--V-------------------GV--NHD-V--SIVGC---KF---LAAD----------G-TG--S------------TSG-------------------------------------A--------IKC--------------I-----------DY---MV---------------GLKNAG-----V------N----------L----RV-----------------------------------------LNNSWG-------G-GGF---S---------------------Q--------------------------ALAD-----AITA-S--------EQA----DI-----L--------------------------------------------------------------------------------------F---------------VAAAG-ND--------AV---------DNDQNP---HYPS---------------------------------------------------------------------------------------------------------------------------------------N-Y--E-N----DN---------------------V---LS---IA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------RD-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-SSF-----S--Q--------W-GL--T--------------------SV------------------------------------------------D-----M------G-----------------A-----P-------------G-----------------SG--------------------------------I------------------------------------------------------------------LS-TVP--------------------------------------------------------------------------------------------------------G-------N--------SY-AT----------------YSG------TSMATPHVA----G---------------------------A------------------AA-L----VL----S-------VNPDLT-----------------------------------------------------TLELKELLMSSGDANAALNGKTVAGTRLNV---------------------NQAL-------IDA------------------------DPT------------------------------------------------------------------------PGFKLSVSPVSQQATVGDTVTYTFTIGSIAQWEGD 372
 373 ------------------IQTNPPSWGLDRIDQR-IGTDGEYR---------FAS-SQGA--------------------------GVT---I--------------Y--------------------LMD---------------------------T--------------GIRQ-D------H-------------S---------D--------------------------------IDG--------------RVTIGKTVVGDTSFD--------NN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-V-----------------------AGVCC----GTK-----------------------------------------------------------------------YGV--AKK-A--NIVSV---KT---LDDE----------G-NG--R------------LSD-------------------------------------V--------LVG--------------L-----------Q-------------------------------------------------------WI-----------------------------------------VEQHISA-FY---------------------------SQPTND------------------------------------AITE---------AIGL----GI-----H--------------------------------------------------------------------------------------F---------------SIAAG-NY-------------------GE-----DACRYS---------------------------------------------------------------------------------------------------------------------------------------P-GSTPGA-------------------------------IT---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FDEDDSVSYY-----S--N--------F-GKC-V----------------------------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TN--------------------------------I------------------------------------------------------------------KS------------------------------------------------------------------------------------------------------------------IWPTSKDAT--HK-------------------LTG------TSMAAPHVA----G---------------------------A------------------MAIF----LSENDYT-----------------------------------------------------------------------------------------------P------------------LQLATYI-------KNTSTLRT-------------------------------------------------------------------------------EDF----------------------------------------------- 373
 374 MQRHAPWGLARVAGSMSLVQRSYCYPV-----------------------------NSGE--------------------------G-V--DV--------------Y--------------------VLD---------------------------T--------------GVEI-D------H-------------P---------E--------------------------------FEG--------------RARWGANFVPE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SQ-----------------------------------------------------------------------------------------DGDDH------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGVIG----GKN-----------------------------------------------------------------------FGI--SKE-S--KIIAV---KV---LDKY----------G-SG--M------------TSR-------------------------------------L--------LQGVDFVIKEHERKKDKLYEAAADKYLNSSG---SSDIEVEIDGSESFSFIRPEPPSIQHLVDIVSEKAL----------QPK--TI-----------------------------------------VNLSVG----------------------------------------------------------------GFRNAALNFAIEY---------ASKL----GI-----H--------------------------------------------------------------------------------------F---------------STAAG-NE------------------------HEDACDFS---------------------------------------------------------------------------------------------------------------------------------------P-GSSKAS-------------------------------IT---TG--A------------------------------STY------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TI-AFF-----S--N--------F-GEC-V----------------------------------------------------------------------N-----I------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LS-SWT------------------------------------------------------------------------------------------------------------------------GGTQKI----------------VSG------TSMAAPHTT----G---------------------------V------------------MAAY----LTYYNYD------------------------------------------------------------------------------PYT--------------L---------------------KSRI-------ISDARVVEDSATSNYEDSILWPLPALLSSKRKKLPMLSMEKLLKRINNK---------------------------------------------------------------------------------------- 374
 375 ------W-------SLSRINSRAKPYFGTA------GYD-----Y-------SAI-DDGS--------------------------N-V--DV--------------Y--------------------IVD---------------------------T--------------GVYI-Q------H-------------Q---------D--------------------------------F--------------------------------------E----------------------S------------------------------RAW----------------------------------------------------------------------------------------------------------------------------------YG------MTADALLHEGNDDH-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAA----GLR----------------------------------------------------Y-------------------GV--AKK-A--NIISV---KV---LDYE----------G-MG--S------------VSG-------------------------------------V--------IQG--------------I-----------QW---AV----------DREA-SKDSAS-----R------G----------R----AV-----------------------------------------LNLSLG-------T-SGV---V---------------------H--------------------------SLDT-----AIQA-A--------ISA----GV-----N--------------------------------------------------------------------------------------V---------------VIAAG-ND--------AA---------D----A---CSVS---------------------------------------------------------------------------------------------------------------------------------------P-G--R-V----AA---------------------A---IS---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------AD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-ASF-----S--N--------F-G---P--------------------CV------------------------------------------------N-----I------L-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------IS-AYK--------------------------------------------------------------------------------------------------------G-----STQ--------MT-QT----------------LSG------TSQAAPLVA----G---------------------------V------------------VARH----LS----S-------LT-PGT-------------------------------------------------------------SLS-PAR--------------V---------------------LALI-------SDT-------------------------AS------------------------------------------------------------------------T----GRISLTSAQG--ATPNLLLYKECTGLPVVG 375
 376 --------------GL----------------------------------------------------------------------G-G--NI--------------F--------------------ILD---------------------------T--------------GVRI-T------H-------------E---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AQ-YAAKF-------------------------VT---------GVNTDCH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAA----GKK-----------------------------------------------------------------------YGV--AKK-A--NIHAV---KV---CDCT----------G-IC--S------------SSA-------------------------------------L--------IQG--------------V-----------DF---VA----------------EQK----AGGM------Q----------NVV--AS-----------------------------------------LSLSLA----SD-------TFA---------------------E-----------------------------------AVHN---------AIDL----DV-----V--------------------------------------------------------------------------------------V---------------LTSSG-ND-RR-----DA------------------CRLI---------------------------------------------------------------------------------------------------------------------------------------P-GNIPEV-------------------------------IT---VG--N------------------------------T----------------------------QE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SI-RSS-----S--N--------F-GEC-V----------------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------VS----------------------------------------------------------------------------------------------------------------------CGNDDDTAT-ST----------------KTG------TSMACPHVA----G---------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 376
 377 ------------------VD------------------------------------------------------------------------I--------------Y--------------------IVD---------------------------S--------------GIRP-T------H-------------I---------D--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HGRVS-CGLNLVP-----DET------------CE-----------------------------------------------------------------------------------------D---L---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAA----GQT-----------------------------------------------------------------------HGV--AKE-A--NLISV---KV---FNRH----------G-VA--L------------ISQ-------------------------------------L--------LGA--------------V-----------EF---VI------------RSRSLRG-------N------G----------T----AV-----------------------------------------VNLSVG-------------TAK--------------------SW--------------------------SLNW-----AIEK---------ASKE----GL-----V--------------------------------------------------------------------------------------F---------------VVGGG-NN--------GG---------N----A---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-SSAE-A---------------------------A---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------AD-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------I-G---P--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------ET--------------------------------I------------------------------------------------------------------LS-ASH-----------------------------------------------------------------------------------------------TSDTATA--T-------------------------------------KSG------TSMATAFVS----G---------------------------A------------------AA-L----YI----E-------QNRSLN----------------------------------------------------AFEIKSSILESTVPGI--------------V---------------------RDLP-------EFL---------------------------------------------------------------------------------------------------ATPNRL----------------------------- 377
 378 --SPRSW-------GLDRIDQMY-LPMDGA-YHPGR--------------------LDGS--------------------------G-S--HI--------------Y--------------------VLD---------------------------T--------------GIRS-T------H-------------Y---------A--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGRVG-AGTSML------GSS------------WE-----------------------------------------------------------------------------------------D---D---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTAM----GAT-----------------------------------------------------------------------YGV--ARA-A--IVHAV---KV---CDSQ----------G-SG--T------------YSN-------------------------------------F--------ISG--------------L-----------GW---VK------------NHVQNNG-------I------K----------Q----AV-----------------------------------------VSMSLS-------------GPR--------------------SA--------------------------SLND-----AIQD---------VVNN----GI-----T--------------------------------------------------------------------------------------V---------------VVAAGNNN--------GG---------D----S---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-GSAP-A---------------------------A---IS---VG--S------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-SSF-----S--N--------V-G---G--------------------CV------------------------------------------------F-----T------F-----------------G-----P-------------G-----------------GS--------------------------------I------------------------------------------------------------------VS-AYN-----------------------------------------------------------------------------------------------TADNAEA--T-------------------------------------MSG------TSMATPHVS----G---------------------------V------------------AA-M----I-----------------LQ----------------------------------------------------AYPGAS-------PAT--------------V---------------------RD-------------------------------------------------------------------------------------------------------------------KL----------------------------- 378
 379 -----SW-------GLDRIDQINLPL----------DDVY-QP----------IG-D-GN--------------------------G-V--DV--------------Y--------------------VID---------------------------T--------------GINI-N------H-------------E---------D--------------------------------Y--------------------------------------A----------------------G------------------------------RST----------------------------------------------------------------------------------------------------------------------------------LG------FDA-F-----GN--T---------------GA-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVA----GTQ----------------------------------------------------Y-------------------GV--AKA-A--NIFGV---RV---LNCM----------G-SG--S------------WSG-------------------------------------V--------VAG--------------C-----------EW---VA----------ENAN------G-----P----------------------SV-----------------------------------------ASMSLG---------GGA---S---------------------T--------------------------TVDD-----AILV-M--------IDA----GI-----T--------------------------------------------------------------------------------------V---------------AVAAG-ND--------DD---------D----A---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----VP---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------TS-SWI--------------------------------------------------------------------------------------------------------G-----GSS--------AT-NT----------------ISG------TSMACPHVA----G---------------------------A------------------AA-V----VL----G-------IN-GTM-------------------------------------------------------------S---PTE--------------V---------------------TNTL-------LTK-------------------------SI------------------------------------------------------------------------S------GAVSDIGS--GSPNLLLYVGEGNGG--- 379
 380 -----SW-------GLDRIDQINLPL----------DDTYNQV----------LG-D-GE--------------------------G-V--SV--------------Y--------------------VLD---------------------------T--------------GINL-N------H-------------Q---------D--------------------------------W--------------------------------------V----------------------G------------------------------RSS----------------------------------------------------------------------------------------------------------------------------------YG------IDT-H-----GG--T---------------GE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIG----GTQ----------------------------------------------------Y-------------------GV--AKA-A--KLIGV---RV---LSCA----------G-SG--A------------YSQ-------------------------------------I--------IDG--------------C-----------DW---VV----------ANAV------L-----P----------------------AV-----------------------------------------ASMSLG---------GGA---N---------------------Q--------------------------ATDD-----AIQR-M--------IDA----GI-----T--------------------------------------------------------------------------------------V---------------VVAAG-ND--------NG---------N----A---CNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-S----EP---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------TS-AWY--------------------------------------------------------------------------------------------------------G-----EPD--------AT-NT----------------ISG------TSMACPHVA----G-----------------------------------------------------------------------MYL-------------------------------------------------------------S---PSV--------------V---------------------P--------------------------------------------------------------------------------------------------------------------------------------------------- 380
 381 ----ASW-------GLDRIDQLSLPL----------DGVF-QP----------IG-NQGQ--------------------------G-V--NI--------------Y--------------------VID---------------------------T--------------GILI-D------H-------------Q---------D--------------------------------F--------------------------------------N----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------VG------FDY-D-----NG--T---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVA----GTA----------------------------------------------------F-------------------GV--AKL-G--HVIAV---RV---LNCF----------G-RG--S------------WAD-------------------------------------I--------ISG--------------C-----------EW---VA----------GNAV------F-----P----------------------AV-----------------------------------------VSMSLG---------GAE---S---------------------E--------------------------SVDD-----AIRA-M--------INA----GI-----S--------------------------------------------------------------------------------------V---------------SVSGG-ND--------DF---------S----S---CRKS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-T----QE---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------AD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---T--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------TS-AWY--------------------------------------------------------------------------------------------------------T-----SVD--------ST-NT----------------ISG------TSMATPHVA----G---------------------------A------------------AA-I----FL----G-------DD-PTM-------------------------------------------------------------T---PAD--------------V---------------------KASI-------QIK-------------------------SI------------------------------------------------------------------------A------GVVGDPQG--GSPNLLLYMGQGSG---- 381
 382 -----SW-------GLDRIDQLSLPL----------DGVF-QP----------IG-NQGQ--------------------------G-V--NI--------------Y--------------------VID---------------------------T--------------GILI-D------H-------------Q---------D--------------------------------F--------------------------------------N----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------VG------FDY-D-----NG--T---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVA----GTA----------------------------------------------------F-------------------GV--AKL-G--HVIAV---RV---LNCF----------G-RG--S------------WAD-------------------------------------I--------ISG--------------C-----------EW---VA----------GNAV------F-----P----------------------AV-----------------------------------------VSMSLG---------GAE---S---------------------E--------------------------SVDD-----AIRA-M--------INA----GI-----S--------------------------------------------------------------------------------------V---------------SVSGG-ND--------DF---------S----S---CRKS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-T----QE---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------AD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---T--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------TS-AWY--------------------------------------------------------------------------------------------------------T-----SVD--------ST-NT----------------ISG------TSMATPHVA----G---------------------------A------------------AA-I----FL----G-------DD-PTM-------------------------------------------------------------T---PAD--------------V---------------------KASI-------QIK-------------------------SI------------------------------------------------------------------------A------GVVGDPQG--GSPNLLLYMGQGCGGN-- 382
 383 -QAVASW-------GLDRIDQRNLPL----------NNNY-NS----------NY-D-GS--------------------------N-V--NV--------------Y--------------------VVD---------------------------T--------------GIWQ-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------R------------------------------RGA----------------------------------------------------------------------------------------------------------------------------------VF------YDA-V-----G-G-N---------------GA-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GIQ----------------------------------------------------Y-------------------GV--AKN-A--NLFGV---RV---LNCL----------G-SG--S------------FSG-------------------------------------I--------VDG--------------M-----------NY---VA----------LYGS------K-----P----------------------AV-----------------------------------------VSMSLG---------GGA---S---------------------S--------------------------LIDN-----AVRS-L--------FNR----GF-----F--------------------------------------------------------------------------------------V---------------SVAAG-NS--------ND---------N----S---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-S----GY---------------------A---MT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------RD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--C--------Y-G---S--------------------CV------------------------------------------------N-----I------W-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS-AWI--------------------------------------------------------------------------------------------------------R-----SDS--------AT-NT----------------ISG------TSMACPHVS----G---------------------------V------------------AA-L----ML----Q-------NN-PNT-------------------------------------------------------------D---PGT--------------L---------------------GNAM-------LSN-------------------------AT------------------------------------------------------------------------P------GLVTDIGF--LSPNQLLFTV-------- 383
 384 TQAVASW-------GLDRIDQRNLPL----------DNSY-NP----------MN-S-GA--------------------------N-V--NV--------------Y--------------------VVD---------------------------T--------------GVWP-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAV----------------------------------------------------------------------------------------------------------------------------------AA------YDA-V-----GNN-N---------------GV-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVA----GTN----------------------------------------------------Y-------------------GV--AKN-A--NIYGI---RV---LGCL----------G-SG--S------------NSG-------------------------------------I--------IDG--------------M-----------DW---VV----------SNGR------R-----P----------------------AV-----------------------------------------VSMSLG---------GGA---S---------------------S--------------------------TTDA-----AVKR-M--------YDA----GF-----T--------------------------------------------------------------------------------------V---------------SVAAG-NS--------DE---------D----A---CGTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-S----GY---------------------A---LT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------TD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------G-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS-AWK--------------------------------------------------------------------------------------------------------G-----SDS--------AT-ST----------------ISG------TSMACPHVS----G---------------------------V------------------AA-L----IL----A-------AS-PSM-------------------------------------------------------------S---PSS--------------V---------------------YSSI-------LSS-------------------------AT------------------------------------------------------------------------S------GKVTDSGR--RSPNLLLFT--------- 384
 385 -----SW-------GLDRVDQRYLPL----------DGQA-DF----------TG-D-GS--------------------------G-V--NV--------------Y--------------------ILD---------------------------T--------------GIYP-S------N-------------T---------Y--------------------------------F--------------------------------------N----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------VG------YDA-V-----GGGQG---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------SGTIG----SDV----------------------------------------------------Y-------------------GI--ARG-A--SLIGI---RV---LNCL----------G-SG--S------------TSQ-------------------------------------V--------LEG--------------L-----------DW---VQ----------TWAR------K-----P----------------------AV-----------------------------------------ASMSLG---------GGV---S---------------------V--------------------------LLDA-----GVTS-L--------TNS----GV-----L--------------------------------------------------------------------------------------V---------------AVSAG-ND--------DH---------E----A---CQNS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-N----PL---------------------A---MT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------QD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---T--------------------CL------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------G-----GPT--------AT-NT----------------ISG------TSMACPHVA----G---------------------------A------------------AV-I----AL----G-------ND-NSL-------------------------------------------------------------A---PDA--------------L---------------------KQKI-------VND-------------------------AT------------------------------------------------------------------------P------D--------------------------- 385
 386 ------W-------GLDRVDQRYLPL----------DGQA-DF----------TG-D-GS--------------------------G-V--NV--------------Y--------------------ILD---------------------------T--------------GIYP-S------N-------------T---------Y--------------------------------F--------------------------------------N----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------VG------YDA-V-----GGGQG---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------SGTIG----SDV----------------------------------------------------Y-------------------GI--ARG-A--SLIGI---RV---LNCL----------G-SG--S------------TSQ-------------------------------------V--------LEG--------------L-----------DW---VQ----------TWAR------K-----P----------------------AV-----------------------------------------ASMSLG---------GGV---S---------------------V--------------------------LLDA-----GVTS-L--------TNS----GV-----L--------------------------------------------------------------------------------------V---------------AVSAG-ND--------DH---------E----A---CQNS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-N----PL---------------------A---MT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------QD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---T--------------------CL------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------G-----GPT--------AT-NT----------------ISG------TSMACPHVA----GTKLSSSHLNPHMPFRELYDRHFTIHIRA------------------AV-I----AL----G-------ND-NSL-------------------------------------------------------------A---PDA--------------L---------------------KQKI-------VND-------------------------AT------------------------------------------------------------------------P------DIVSDPKS--GSPNLLLY---------- 386
 387 VQSPATW-------GLDRIDQRTLPL----------DGRY-TY----------TA-T-GA--------------------------G-V--HA--------------Y--------------------VVD---------------------------T--------------GILL-S------H-------------Q---------E--------------------------------F--------------------------------------T----------------------G------------------------------RIG----------------------------------------------------------------------------------------------------------------------------------KG------YDAIT-----PGGSAQ---------------------------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----GTT----------------------------------------------------Y-------------------GV--AKG-V--TLHPV---RV---LDCN----------G-SG--S------------NSS-------------------------------------V--------IAG--------------L-----------DW---VT----------QNHV------K-----P----------------------AV-----------------------------------------INMSLG---------GGA---S---------------------T--------------------------ALDT-----AVMN-A--------INA----GV-----T--------------------------------------------------------------------------------------V---------------VVAAG-ND--------NR---------D----A---CFYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----TA---------------------A---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------Y-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---R--------------------CL------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------QS--------------------------------I------------------------------------------------------------------TS-AWY--------------------------------------------------------------------------------------------------------T-----SST--------AT-NT----------------ISG------TSMATPHVT----G---------------------------A------------------AA-L----YL----Q-------WY-PTA-------------------------------------------------------------T---PSQ--------------V---------------------ASAL-------LYY-------------------------AT------------------------------------------------------------------------P------NVVKNAGR--YSPNLLLYTPF------- 387
 388 TQSPAPW-------GLDRIDQRDLPL----------SNSY-T----------YTA-T-GR--------------------------G-V--NV--------------Y--------------------VID---------------------------T--------------GIRT-T------H-------------R---------E--------------------------------F--------------------------------------G----------------------G------------------------------RAR----------------------------------------------------------------------------------------------------------------------------------VG------YDA-L------G-GN---------------GQ-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----GVT----------------------------------------------------Y-------------------GV--AKA-V--NLYAV---RV---LDCN----------G-SG--S------------TSG-------------------------------------V--------IAG--------------V-----------DW---V------------TRN----HRR-----P----------------------AV-----------------------------------------ANMSLG---------GGV---S---------------------T--------------------------ALDN-----AVKN-S--------IAA----GV-----V--------------------------------------------------------------------------------------Y---------------AVAAG-ND--------NA---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----AE---------------------A---LT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---S--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------AS--------------------------------I------------------------------------------------------------------PS-AWY--------------------------------------------------------------------------------------------------------T-----SDT--------AT-QT----------------LNG------TSMATPHVA----G---------------------------V------------------AA-L----YL----E-------QN-PSA-------------------------------------------------------------T---PAS--------------V---------------------ASAI-------LNG-------------------------AT------------------------------------------------------------------------T------GRLSGIGS--GSPNRLLYSLLSSGSGST 388
 389 NQTNAIW-------GLDRIDQRNLPL----------DNNY-SA----------NF-D-GT--------------------------G-V--TA--------------Y--------------------VID---------------------------T--------------GVNN-A------H-------------V---------E--------------------------------F--------------------------------------G----------------------G------------------------------RSV----------------------------------------------------------------------------------------------------------------------------------SG------YDF-V-----DNDAD---------------AS-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----GSL----------------------------------------------------Y-------------------GV--AKN-V--NLVGV---RV---LSCS----------G-SG--S------------TSG-------------------------------------V--------IAG--------------V-----------DW---V------------AAN----ASG-----P----------------------SV-----------------------------------------ANMSLG---------GGQ---S---------------------V--------------------------ALDS-----AVQS-A--------VQS----GV-----S--------------------------------------------------------------------------------------F---------------MLAAG-NS--------NA---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----AT---------------------G---VT---VG--S------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------W-G---S--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------SQ--------------------------------I------------------------------------------------------------------KS-AWY---------------------------------------------------------------------------------------------------------------DG--------GY-KT----------------ISG------TSMATPHVA----G---------------------------V------------------AA-L----YL----Q-------EN-SSV-------------------------------------------------------------S---PSQ--------------V---------------------EALI-------VSR-------------------------AS------------------------------------------------------------------------T------GKVTDT-R--GSVNKLLYSLTDADCGQD 389
 390 ------W-------GLDRVDQRSLPL----------NNRY-SS---------HNG-A-GS--------------------------G-K--TV--------------Y--------------------VID---------------------------T--------------GVKD-S------H-------------N---------D--------------------------------F--------------------------------------S----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------QV------VNY-A------G-GS---------------NA-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---KV---LNCL----------G-SG--S------------NSG-------------------------------------V--------ISG--------------I-----------NY---VI----------NAAR----SSS-----N----------------------LI-----------------------------------------ASMSLG---------GGA---S---------------------T--------------------------SLDN-----AVKN-L--------VSA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NK---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----ST---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------TD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----SNS--------AT-KT----------------ISG------TSMACPHVA----G---------------------------A------------------LA-C----Y------------------------------------------------------------------------------------GTS--------------S-----------------------KM-------LAN-------------------------------------------------------------------------------------------------------------------------------------- 390
 391 -----TW-------GLDRVDQRSLPL----------NNKY-SS---------HNG-A-GS--------------------------G-K--TV--------------Y--------------------VID---------------------------T--------------GVRA-T------H-------------N---------D--------------------------------F--------------------------------------S----------------------G------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------QV------ANY-A------G-GD---------------NT-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---KV---LNCV----------G-SG--S------------NSG-------------------------------------V--------ISG--------------I-----------NY---VI----------DAAR----WNS-----N----------------------LI-----------------------------------------ASMSLG---------GGA---S---------------------T--------------------------SLDN-----AVKN-M--------VSA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NA---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----ST---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------ND-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----TNS--------AT-KT----------------ISG------TSMACPHVA----G---------------------------A------------------LA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------NM-------LAN-------------------------TS------------------------------------------------------------------------N------YKISNTGS--GSPNKLLYV--------- 391
 392 ------W-------GLDRVDQRSLPL----------NNKY-SS---------HNG-A-GS--------------------------G-K--TV--------------Y--------------------VID---------------------------T--------------GVRA-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------QS------VNY-A------T-GN---------------NE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---KV---LNCL----------G-TG--S------------NSG-------------------------------------I--------ING--------------I-----------NY---VI----------NAAK----SSS-----N----------------------LV-----------------------------------------ASMSLG---------GGA---S---------------------T--------------------------SLDN-----AVKN-L--------VNA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NK---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----SS---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----SNS--------AT-KT----------------ISG------TSMACPHVA----G---------------------------A------------------IA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------KM-------LAN-------------------------TS------------------------------------------------------------------------N------NKISNAGS--GSTNKLLY---------- 392
 393 -----TW-------GLDRIDQRSLPL----------NNKY-SS---------HNG-A-GS--------------------------G-K--TV--------------Y--------------------VLD---------------------------T--------------GVRA-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------S------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------QV------ANY-A------G-GN---------------NE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SST----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---KV---LNCA----------G-SG--S------------TSG-------------------------------------I--------VNG--------------I-----------NY---VI----------NAAR----WNS-----N----------------------LV-----------------------------------------ASMSIG---------GGT---S---------------------T--------------------------SLDN-----AVKN-L--------VNA----GV-----P--------------------------------------------------------------------------------------T---------------AVSAG-ND--------NT---------N----A---CNQS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----ST---------------------A---IT---VA--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------SD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----SNS--------AT-KT----------------ISG------TSMACPHVA----G------------MHGFLNC--------A------------------IA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------KM-------LAN-------------------------TS------------------------------------------------------------------------N------YKISNTGS--GSPNKLLYV--------- 393
 394 ------W-------GLDRVDQRSLPL----------DNKY-SS---------HNG-K-GS--------------------------G-K--TV--------------N--------------------VID---------------------------T--------------GVRA-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------QV------ANF-D------G-GN---------------NE-----------------------------------------------------------------------------------------D---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---KV---LGCG----------G-TG--S------------NSG-------------------------------------V--------IAG--------------V-----------NY---VT----------NIAK----STK-----N----------------------LV-----------------------------------------ASMSLG---------GDA---S---------------------T--------------------------SLDN-----AVKS-M--------INA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NK---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-L----SN---------------------A---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------TD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-WYA-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------AS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----GNS--------AT-NT----------------ISG------TSMACPHVA----G------------MHGFYSPTVLLVATCA------------------IA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------KM-------MAN-------------------------TS------------------------------------------------------------------------N------NKISDIKS--GSPNKLLY---------- 394
 395 -----TW-------GLDRVDQRSLPL----------DNKY-SS---------HNG-K-GS--------------------------G-K--TV--------------Y--------------------VID---------------------------T--------------GVRA-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------QV------ANF-A------G-GN---------------NA-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GV--AKS-V--QIRGV---RV---FGCG----------D-TG--S------------TSD-------------------------------------I--------IAG--------------V-----------NY---VT----------NIAK----STS-----N----------------------LI-----------------------------------------ASMSLR---------GGA---S---------------------T--------------------------AMDN-----AVKS-M--------INA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NK---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-L----SN---------------------A---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------QD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-WSS-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------AS--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----GNS--------AT-NT----------------ISG------TSMACPHVA----G---------------------------A------------------IA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------KM-------MAN-------------------------TS------------------------------------------------------------------------N------NKISDIKS--GSPNKLLYV--------- 395
 396 -----TW-------GLDRVDQRNLPL----------DNKY-SS---------HNG-K-GS--------------------------G-K--TV--------------Y--------------------VID---------------------------T--------------GVRA-T------H-------------T---------N--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------QV------ANY-A------G-GN---------------NE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GV--ATS-V--QIRGV---KV---LGCY----------G-TG--S------------NSA-------------------------------------I--------ISG--------------V-----------NY---VT----------NIAK----STN-----N----------------------LV-----------------------------------------ASMSLG---------GGA---S---------------------T--------------------------SLDN-----AVKS-M--------INA----GV-----P--------------------------------------------------------------------------------------T---------------AVAAG-NS--------NK---------D----A---CTTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-L----SN---------------------A---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------KD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-WSS-----S--N--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------AS--------------------------------I------------------------------------------------------------------TS-TWH--------------------------------------------------------------------------------------------------------T-----GNS--------AT-NT----------------ISG------TSMACPHVA----G---------------------------A------------------IA-C----Y------------------------------------------------------------------------------------GSS--------------S-----------------------KM-------MAN-------------------------TS------------------------------------------------------------------------N------NKISDIKS--GSPNKLLYV--------- 396
 397 -----TW-------GLDRVDQRDLPL----------DNSY-SP----------SG-T-GA--------------------------G-H--TV--------------Y--------------------VID---------------------------T--------------GVYA-S------S-----------------------D--------------------------------F--------------------------------------G----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------QK------ANF-A-----RG--D---------------NE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIG----STT----------------------------------------------------Y-------------------GV--AKG-V--NIVGV---KV---LNCI----------G-SG--S------------TSG-------------------------------------I--------VGG--------------C-----------DF---VI----------SDVQ---ANNN-----K----------------------GV-----------------------------------------ASMSLG---------GGA---S---------------------L--------------------------TLDR-----AVKS-M--------IDA----GI-----P--------------------------------------------------------------------------------------T---------------AVAAG-NS--------NE---------D----A---QNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-L----EE---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------ND-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------TL------------------------------------------------D-----I------W-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------TS-WW---------------------------------------------------------------------------------------------------------------KDG--------TE-RT----------------ISG------TSMACPHVA----G---------MYSMAVKSTGDWYFIAQSA------------------IA-V----YG----Q-----------------------------------------------------------------------------------------------D---------------------TDAM-------LAN-------------------------AS------------------------------------------------------------------------E------GKISDVKI--GSPTKFLYV--------- 397
 398 -----SW-------GLDRIDQASLPL----------NDQY-NP----------SG-T-GS--------------------------G-W--SV--------------Y--------------------VID---------------------------T--------------GVMA-S------H-------------N---------D--------------------------------F---------------------V----------------A----------------------R------------------------------RTS----------------------------------------------------------------------------------------------------------------------------------QL------VNY-A------GDGE---------------DE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SQT----------------------------------------------------Y-------------------GV--ATG-V--NIYGV---KV---LNCA----------G-SG--S------------TAG-------------------------------------V--------IAG--------------V-----------EY---V------------QAN----APG-----N----------------------SV-----------------------------------------ASMSLG---------GGP---S---------------------S--------------------------SLDD-----AVNS-L--------VSS----GV-----P--------------------------------------------------------------------------------------C---------------AVAAG-NS--------DI---------N----A---CFAS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----TS---------------------A---TT---VG--S------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------LD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------W-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------TS-TWI--------------------------------------------------------------------------------------------------------G-----SDS--------AT-NT----------------ISG------TSMACPHVA----G---------------------------A------------------LA-L----Y------------------------------------------------------------------------------------GKS--------------T---------------------DGDL-------IAA-------------------------GT------------------------------------------------------------------------Q------NALSDVGT--GSPNILLRVMKPTD---- 398
 399 -----SW-------GLDRVDQRYLPL----------DNSY-TP----------SA-T-GG--------------------------D-V--VV--------------Y--------------------VID---------------------------T--------------GVNQ-D------H-------------V---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------HA------WTY-T------G-GT---------------AE-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIVG----SKT----------------------------------------------------Y-------------------GV--ATE-V--QIKGV---KV---LNCY----------G-SG--S------------YSN-------------------------------------M--------IA-----------------------------------------------------------------------------------------------------------------------------------G---------GGA---S---------------------T--------------------------SLDT-----AIRE-L--------VSS----GV-----P--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NA---------D----A---CNFS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----PS---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------TD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-RSS-----S--N--------H-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SE--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----SNT--------AT-AV----------------LSG------SSMACPHVA----G---------------------------A------------------LA-L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 399
 400 -----SW-------GLDRVDQRYLPL----------DNSY-TP----------SA-T-GG--------------------------D-V--VV--------------Y--------------------VID---------------------------T--------------GVNQ-D------H-------------V---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------HA------WTY-T------G-GT---------------AE-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIVG----SKT----------------------------------------------------Y-------------------GV--ATE-V--QIKGV---KV---LNCY----------G-SG--S------------YSN-------------------------------------M--------IAG--------------I-----------NH---DS------------------VGR-----A----------------------AV-----------------------------------------ASMSVG---------GGA---S---------------------T--------------------------SLDT-----AIRE-L--------VSS----GV-----P--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NA---------D----A---CNFS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----PS---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------------------------------------------------------------------TD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-RSS-----S--N--------H-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SE--------------------------------I------------------------------------------------------------------TS-TWY--------------------------------------------------------------------------------------------------------T-----SNT--------AT-AV----------------LSG------SSMACPHVA----G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 400
 401 -----SW-------GIDRIDART-GL----------DQTY-SP----------AL-T-GA--------------------------G-Y--TV--------------Y--------------------VID---------------------------T--------------GVND-Q------H-------------V---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------QVFCADNLYTV-I------G-GG---------------NE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------SGTVG----SNT----------------------------------------------------Y-------------------GV--AKG-V--NIVGV---KV---LGCL----------G-SG--S------------NAG-------------------------------------V--------IQG--------------I-----------EW---VI----------SNAR----SGR-----S-----------------------V-----------------------------------------ASMSLG---------SGY---N---------------------Q--------------------------ATND-----AVNA-M--------VDA----GI-----Q--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NA---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----AK---------------------A---TS---VG--S------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F-------------------------------------------------------------------------------------AD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------TS-TWI--------------------------------------------------------------------------------------------------------G-----GTD--------AT-RT----------------ISG------TSMACPHVA----G---------------------------A------------------LT-L----Y--------------------------------------------------------------------------------------E--------------T---------------------RNDL-------LLA-------------------------GT------------------------------------------------------------------------P------GVIQDVGS--GSPNLFLYV--------- 401
 402 -----SW-------GLDRIDQANLPL----------DDSY-DSTK-------RGT-N-GA--------------------------G-Y--NV--------------Y--------------------VID---------------------------T--------------GINP-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAV----------------------------------------------------------------------------------------------------------------------------------TA------WS--A------M-AR---------------SE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------SGTVA----GTE----------------------------------------------------Y-------------------GV--AKG-V--NVYGV---KV---LNCF----------G-SG--S------------WSD-------------------------------------V--------IAG--------------V-----------DW---V------------SAS----GAR-----P----------------------AV-----------------------------------------ASMSLG---------GGY---T---------------------D--------------------------SLNE-----AVKN-L--------VNS----GV-----Q--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NS---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-E----PE---------------------A---VT---VG--S------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---N--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------TS-AWY--------------------------------------------------------------------------------------------------------T-----SNT--------AT-NT----------------ISG------TSMACPHVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 402
 403 ------------TWGLDRIDQRFLPLDNSFDP------LGDGG-------------Y-----------------------------Y-Y--TV--------------Y--------------------VLD---------------------------T--------------GIRD-T------H-------------N---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-GR-------------------------------------AD-HI-------------------------------EDVNFAGDGKNYECN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SRN-----------------------------------------------------------------------YGV--AKS-V--QIKGV---KV---LSCE----------G-YG--S------------VSG-------------------------------------I--------VAG--------------C-----------EY---VM----------------G--------IA------T----------KGY--SV-----------------------------------------VSMSIG-GGYST-------SFN---------------------A-----------------------------------AIDA---------LYNA----QI-----P--------------------------------------------------------------------------------------A---------------VVSAG-ND-NN-----DA------------------CLQS---------------------------------------------------------------------------------------------------------------------------------------P-ASAEYA-------------------------------IT---VG--A------------------------------T----------------------------DV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-SSF-----S--N--------Y-GSC-V----------------------------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TY--------------------------------I------------------------------------------------------------------ES----------------------------------------------------------------------------------------------------------------------TWYTSDTST-YF----------------MSG------TSMACPHVA----G---------------------------A------------------VT-------------------------------------------------------------------------------------------------------------------------------------L-------FG--------------------------------------------------------------------------------------------------NLFNMFNRASMDKLSDLGQDSPNSLLYV--------- 403
 404 -------------WGLDRIDQRELPLDGIANF------KGNGS-------------------------------------------G-I--NA--------------Y--------------------IID---------------------------T--------------GIYP-E------S-------------L---------Y--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-GR-------------------------------------ATPAF-------------------------------DASPKKGAYGI-DCN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIIG----GNT-----------------------------------------------------------------------YGV--ARG-V--ELFGV---RA---L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D---------------------N-----------------------------------AVQG---------LIDA----GV-----I--------------------------------------------------------------------------------------V---------------VAAAG-NF-DM-----HA------------------CKSS---------------------------------------------------------------------------------------------------------------------------------------P-ARVTEA-------------------------------IT---VG--A------------------------------T----------------------------DI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-ADF-----S--N--------Y-GKC-V----------------------------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------PS----------------------------------------------------------------------------------------------------------------------AWIGGPEET-RI----------------LSG------TSMACPHVA----G---------------------------A------------------AAIALG----------------NTRGQS-----------------------------------------------------------------PTQ--------------L---------------------KQEI-------IDN-------------------------------------------------------------------------------------------------ATTDVISKVG--------QRSPNRLLY---------- 404
 405 ------W-------GLDRVDQRLLPL----------NGKA-EF----------SG-D-GT--------------------------G-V--NV--------------Y--------------------VID---------------------------T--------------GIAP-D------S-------------L---------Y--------------------------------F--------------------------------------E----------------------G------------------------------RAV----------------------------------------------------------------------------------------------------------------------------------AA------FDS-V-----GDADY---------------GI-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNM----------------------------------------------------Y-------------------GV--AKD-V--KLFGV---KV---LGCD----------G-TG--S------------TSG-------------------------------------V--------IAG--------------V-----------DF---VA----------TSGQ------K-----P----------------------AV-----------------------------------------ASMSLG---------GGR---N---------------------N--------------------------ALDD-----ALKS-L-------IIDA----GI-----T--------------------------------------------------------------------------------------V---------------VAAAG-NS--------DD---------D----A---CRYS---------------------------------------------------------------------------------------------------------------------------------------P-A--G-V----EQ---------------------V---IT---VG--A------------------------------T-----------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------DD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---E--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------PS-AYI--------------------------------------------------------------------------------------------------------G-----GIE--------ET-RT----------------FSG------TSMACPHVT----G---------------------------A------------------VA-I----LL----A-------NN-PNL-------------------------------------------------------------T---PAE--------------I---------------------AAKV-------IEM-------------------------ST------------------------------------------------------------------------K------DLVTDPGY--DSPNRLLY---------- 405
 406 ------W-------GLDRISQRLLPL----------DGDY-SF----------TG-N-GS--------------------------G-V--NV--------------Y--------------------VID---------------------------T--------------GIYP-Q------S-------------T---------Y--------------------------------F--------------------------------------G----------------------E------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------VA------YDA-I-----GTGTY---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----AEI----------------------------------------------------F-------------------GV--APG-V--NLFGV---RV---LDCD----------G-SG--S------------AAD-------------------------------------I--------IAG--------------C-----------DY---VA----------KSSE------K-----P----------------------AV-----------------------------------------ASMSLG---------GGA---Q---------------------V--------------------------ALDD-----AVRG-M--------INA----GI-----T--------------------------------------------------------------------------------------T---------------AVAGG-NS--------ND---------D----S---CLFS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----TE---------------------A---IT---VG--A------------------------------T-----------------------------F------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------ND-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---T--------------------CL------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------PS-VSI--------------------------------------------------------------------------------------------------------R-----GEE--------VV-QV----------------YSG------TSMACPHVA----G---------------------------A------------------VA-I----AL----G-------NS-EGM-------------------------------------------------------------S---PSD--------------L---------------------KLKL-------MDD-------------------------TT------------------------------------------------------------------------R------DVVADAQP--GSPNRLLY---------- 406
 407 ------W-------GLDRISQRLLPL----------DGDY-SF----------SG-N-GS--------------------------G-V--NV--------------Y--------------------VLD---------------------------T--------------GIYP-Q------S-------------V---------Y--------------------------------F--------------------------------------G----------------------G------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------VA------YDA-I-----GTQAY---------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----AEI----------------------------------------------------F-------------------GV--APG-V--KLFGV---RV---LDCD----------G-SG--S------------TAD-------------------------------------V--------VAG--------------C-----------DY---VA----------KSSE------Q-----P----------------------AV-----------------------------------------ASMSLG---------GGI---Q---------------------P--------------------------ALDD-----AVRG-I--------INA----GI-----T--------------------------------------------------------------------------------------T---------------VVSAG-NS--------NN---------N----S---CLQS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----TQ---------------------A---IT---VG--A------------------------------T-----------------------------F------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------ND-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---A--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------PS-VSI--------------------------------------------------------------------------------------------------------R-----GGE--------VL-EV----------------FSG------TSMSCPHVA----G---------------------------A------------------VA-I----AL----G-------NS-EGM-------------------------------------------------------------S---PRD--------------L---------------------KQKI-------MDD-------------------------TT------------------------------------------------------------------------T------DVVADARP--GSPNRLLY---------- 407
 408 ------W-------GLDRIDERYLPL----------DGNI-NF----------SG-T-GS--------------------------G-A--NV--------------F--------------------VLD---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------D----------------S----------------------N------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------SF------WDY-N-----GGD-----------------GS-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GRY----------------------------------------------------S-------------------GV--ATG-T--NIYSV---RV---LSCW----------G-TG--S------------TSN-------------------------------------I--------IAG--------------L-----------DA---VA----------DSSM------S-----R----------------------KI-----------------------------------------ASMSLG---------GGY---S---------------------W--------------------------SLNN-----AVAS-A--------HDA----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NS--------YD---------D----A---CDYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SD---------------------A---IT---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PSF-----S--C--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------KS-AEH--------------------------------------------------------------------------------------------------------E-----TSS--------SY-TN----------------FSG------TSMACPHVA----G---------------------------A------------------AA-V----IL----G-------NN-SGY-------------------------------------------------------------S---PTQ--------------V---------------------ASKL-------VSD-------------------------AT------------------------------------------------------------------------S------GVLSNTGS--GSPNLLLY---------- 408
 409 ------W-------GLDRIDERYLPL----------DGNI-NF----------SG-T-GS--------------------------G-V--NV--------------F--------------------VLD---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------N----------------S----------------------N------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------NF------WDY-D-----GGD-----------------GS-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GQY----------------------------------------------------S-------------------GV--ATS-A--NIYSV---RV---LSCT----------G-SG--S------------YSN-------------------------------------I--------ISG--------------L-----------NA---VA----------DSSR------S-----R----------------------KI-----------------------------------------ASMSLG---------GGY---S---------------------W--------------------------SLNS-----AVAS-A--------HDA----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------YD---------D----A---CDYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SD---------------------A---IT---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PYF-----S--C--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------DD--------------------------------V------------------------------------------------------------------NS-AKY--------------------------------------------------------------------------------------------------------G-----TSS--------SY-TE----------------MSG------TSMACPHVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 409
 410 ------------------------------------------T----------TG-T-GS--------------------------G-A--NV--------------F--------------------VID---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------N----------------S----------------------N------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------SF------YDY-E-----GGD-----------------GA-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GQY----------------------------------------------------S-------------------GV--ATN-T--NIYNV---RV---MSCT----------G-SG--S------------TSN-------------------------------------I--------IDG--------------L-----------NA---VA----------DSSR------S-----R----------------------KI-----------------------------------------ASMSLG---------GGY---S---------------------W--------------------------SLNN-----AVAS-A--------HDD----GV-----T--------------------------------------------------------------------------------------V---------------VAAAG-NS--------YQ---------D----A---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PD---------------------A---IT---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PLF-----S--C--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------NS-AKY--------------------------------------------------------------------------------------------------------G-----TSS--------SY-TE----------------MDG------TSMACPAVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 410
 411 ------W-------GLDRIDERYLPL----------DGNI-NF----------SG-T-GS--------------------------G-A--NV--------------F--------------------VID---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------N----------------S----------------------N------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------SF------YDY-E-----GGD-----------------GA-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GQY----------------------------------------------------S-------------------GV--ATN-T--NIYNV---RV---MSCT----------G-SG--S------------TSN-------------------------------------I--------IDG--------------L-----------NA---VA----------DSSR------S-----R----------------------KI-----------------------------------------ASMSLG---------GGY---S---------------------W--------------------------SLNN-----AVAS-A--------HDD----GV-----T--------------------------------------------------------------------------------------V---------------VAAAG-NS--------YQ---------D----A---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PD---------------------A---IT---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PLF-----S--C--------Y-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------NS-AKY--------------------------------------------------------------------------------------------------------G-----TSS--------SY-TE----------------MDG------TSMACPAVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 411
 412 ------Y-------GLDRIDQRNLPL----------DGTI-NF----------SG-T-GS--------------------------G-A--NV--------------F--------------------VID---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------S----------------N----------------------N------------------------------RAN----------------------------------------------------------------------------------------------------------------------------------QF------YDY-E-----NGD-----------------GA-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GTY----------------------------------------------------S-------------------GV--ATN-T--NIYNV---RV---MSCT----------G-SG--S------------YSN-------------------------------------I--------IAG--------------V-----------NA---VA----------ESSM------S-----N----------------------KI-----------------------------------------ASMSIG---------GGS---S---------------------W--------------------------SLNN-----AVAN-A--------HDA----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NS--------YA---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PD---------------------A---IT---VG--A------------------------------T-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PLF-----S--N--------Y-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------NS-AQY--------------------------------------------------------------------------------------------------------G-----TSS--------SY-TQ----------------MSG------TSMACPHVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 412
 413 ------W-------GLDRIGGRSLPL----------DGNI-SF----------TG-T-GE--------------------------G-A--NV--------------F--------------------VVD---------------------------T--------------GITY-S------H-------------E---------D--------------------------------F---------------------D----------------S----------------------N------------------------------RAH----------------------------------------------------------------------------------------------------------------------------------KF------FDY-E-----SGD-----------------GS-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GMY----------------------------------------------------S-------------------GV--ATN-T--DIYSV---RA---MSCT----------G-SG--S------------YSN-------------------------------------I--------IVG--------------L-----------NA---VA----------ESGM------S-----N----------------------KI-----------------------------------------ASMSLG---------GGY---S---------------------V--------------------------SLNN-----AVAN-A--------HGA----GV-----T--------------------------------------------------------------------------------------V---------------VVPAG-NG--------GA---------D----A---CYYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PD---------------------A---IT---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------DD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-PSF-----S--N--------Y-G---S--------------------CM------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------ID--------------------------------I------------------------------------------------------------------NS-AKY--------------------------------------------------------------------------------------------------------D-----TSS--------SY-IS----------------KTG------TSMACSHVA----G---------------------------A------------------AA-V----IL----G-------NI-SGF-------------------------------------------------------------S---PTQ--------------V---------------------ASKL-------VSD-------------------------AT------------------------------------------------------------------------S------GALSNTGS--GSPNLFLH---------- 413
 414 ------------TWGLDRIDQTNLPLDGRYNP------FATGK-------------------------------------------G-Y--TV--------------R--------------------LLD---------------------------S--------------GIRS-S------H-------------N---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AY-HV---------------------------------ANFA-DKHDYDCY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----AKN-----------------------------------------------------------------------YGV--ASE-V--TIYSV---KV---FDCN----------G-YA--T------------TSW-------------------------------------I--------IKA--------------V-----------DY---TI----------------E--------YA------N----------R-Y--SV-----------------------------------------ASMSIG-GGKSR-------SMD---------------------E-----------------------------------SVEE---------LVKS----GV-----P--------------------------------------------------------------------------------------A---------------AVAAG-NE-NE-----NA------------------CDHS---------------------------------------------------------------------------------------------------------------------------------------P-AAAPSA-------------------------------IT---VG--A------------------------------S----------------------------DW--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LR-AEF-----S--N--------W-GPC-L----------------------------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------LY--------------------------------I------------------------------------------------------------------DS----------------------------------------------------------------------------------------------------------------------LGYRTDYEI-TQ----------------KSG------TSMACPHVA----G---------------------------A------------------IA-------------------------------------------------------------------------------------------------------------------------------------L-------YAK-------------------------------------------------------------------------------------------------NTDNLLAYSNKDKLGWLSSACPNKLLYV--------- 414
 415 -------TSSGVEWNLDRIDQHD-GLNGAYNP------KGNGK-------------------------------------------G-V--DV--------------Y--------------------ILD---------------------------T--------------GIRY-T------H-------------D---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-GR-------------------------------------AK-YVGYD-------------------------AIDELVKTNSPKKGLDCN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AATVG----GKT-----------------------------------------------------------------------YGV--AKG-V--ALYSA---RV---LDCT----------G-TG--S------------IGG-------------------------------------I--------LDA--------------M-----------NY---II----------------KKR----KTSG------T----------SRR--AV-----------------------------------------FSMSLG-VKKNK-------GFN---------------------L-----------------------------------AVNN---------AVKA----GI-----V--------------------------------------------------------------------------------------V---------------ASASG-NQ-MS-----DS------------------CMYS---------------------------------------------------------------------------------------------------------------------------------------P-GSAELS-------------------------------IS---VA--A------------------------------S----------------------------SK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ES-ASF-----S--N--------I-GLC-T----------------------------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------YD--------------------------------I------------------------------------------------------------------LS----------------------------------------------------------------------------------------------------------------------AGHDCDSCT-AS----------------KSG------TSMACPHVA----G---------------------------Y------------------AAIVLG----------------LNGQYS-----------------------------------------------------------------PSD--------------V---------------------KKEM-------IKV-------------------------------------------------------------------------------------------------SSKKKIN--MNEMTASLATMTPNRLLY---------- 415
 416 ------W-------GLDRINQRDLPF----------DDSY-TP----------AG-N-GS--------------------------G-V--NV--------------Y--------------------VLD---------------------------T--------------GIRT-T------H-------------E---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------FS------YDA-M-----NY--AIGN------------DG-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIA----GKR----------------------------------------------------Y-------------------GV--AKA-A--KVYAV---RV---LGCY----------G-SG--S------------WSA-------------------------------------V--------IDG--------------M-----------DW---VA----------SNGI------R-----P----------------------AV-----------------------------------------ASMSLG---------GGG---L---------------------R--------------------------AVDE-----SLGN-L--------HRA----GV-----T--------------------------------------------------------------------------------------V---------------VVAAG-NS--------DL---------D----A---CTSS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----PE---------------------A---IT---VG--A------------------------------I-----------------------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------DD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-VYF-----S--N--------W-G---A--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------RG--------------------------------I------------------------------------------------------------------LS-ADY--------------------------------------------------------------------------------------------------------R-----SDD--------SY-RS----------------LSG------TSMACPHVA----G---------------------------V------------------AA-I----HL----G-------LN-PNL-------------------------------------------------------------S---PDS--------------V---------------------RDVI-------LES-------------------------AS------------------------------------------------------------------------R------DKVTEL-H--DSENLLLY---------- 416
 417 ------W-------GLDRINQRDLPL----------DDSF-TP----------IG-N-GS--------------------------G-V--NV--------------Y--------------------VLD---------------------------T--------------GIRT-T------H-------------E---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------FS------YDA-M-----NY--AIGN------------DG-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIA----GKR----------------------------------------------------Y-------------------GV--AKA-A--KVYAV---RV---LGCY----------N-YG--S------------WSS-------------------------------------I--------IDG--------------M-----------DW---VA----------RNGI------R-----P----------------------AI-----------------------------------------ASMSLG---------GGG---T---------------------R--------------------------AVDE-----SLRN-L--------HRD----GV-----A--------------------------------------------------------------------------------------V---------------VVAAM-NN--------DL---------D----S---CAYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----PE---------------------A---IT---VG--A------------------------------I-----------------------------Q------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------DD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-VYF-----S--N--------W-G---A--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------HR--------------------------------I------------------------------------------------------------------LS-ADY--------------------------------------------------------------------------------------------------------Q-----SDN--------GY-RL----------------LSG------TSMACPHVA----G---------------------------V------------------AA-I----HL----G-------LN-PNL-------------------------------------------------------------S---PDS--------------L---------------------RDVI-------LES-------------------------AS------------------------------------------------------------------------R------DKVTEL-H--DSENLLLY---------- 417
 418 YADTTTW-------GLDRLDQRDLPL----------DDSY-MP----------VG-DGGA--------------------------G-V--NV--------------Y--------------------VLD---------------------------T--------------GIRT-T------H-------------E---------E--------------------------------F--------------------------------------E----------------------D------------------------------RGADGDCRGHGTHCASTIGG------------------------------------------------------------------------------------------------------KVYGVAPKAKLFS----------------------GA------------DG-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------ASTIG----GKV----------------------------------------------------Y-------------------GV--APK-A--HVHSV---RV---LGCS----------G-SG--S------------KGG-------------------------------------V--------MAG--------------M-----------DW---VA----------ENGE------R-----P----------------------AI-----------------------------------------VSMSLG---------GSG---S---------------------Y--------------------------AEDE-----VLTN-L--------DAS----GV-----L--------------------------------------------------------------------------------------V---------------VVAAG-NS--------DY---------E----A---CRRS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-S----RE---------------------A---LT---VG--A------------------------------S-----------------------------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------DD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------W-G---G--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------RY--------------------------------I------------------------------------------------------------------TA-ASW--------------------------------------------------------------------------------------------------------L-----GDD--------LY-RS----------------ISG------TSMATPHVA----G---------------------------V------------------AA-V----HL----G-------VN-PNY-------------------------------------------------------------S---TRE--------------L---------------------RDII-------MNS-------------------------AA------------------------------------------------------------------------R------NKIGDP-H--GAPDLLLQIPRA------ 418
 419 ------W-------GLDRIDQRDLPL----------DDSY-TP----------FA-L-GE--------------------------G-A--HV--------------Y--------------------ILD---------------------------T--------------GLRT-T------H-------------V---------E--------------------------------F--------------------------------------E----------------------D------------------------------RGT----------------------------------------------------------------------------------------------------------------------------------FA------YDA-T-----KR-DDEGS------------GT-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-C-----------------------AGTAA----GKD----------------------------------------------------Y-------------------GV--APK-A--MIYGV---RV---LGCT----------G-SG--S------------WSG-------------------------------------I--------IDG--------------M-----------EW---VA----------TNGN------R-----P----------------------AV-----------------------------------------ASMSLS---------GTA---T--------------------GT--------------------------VVDQ-----AVSG-M--------VAA----GV-----T--------------------------------------------------------------------------------------L---------------TVSAG-NN--------DY---------D----A---CQRM---------------------------------------------------------------------------------------------------------------------------------------P-A--R-S----ME---------------------A---IT---VG--A------------------------------T-----------------------------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------DD-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---G--------------------CV------------------------------------------------N-----L------F-----------------A-----P-------------G-----------------RY--------------------------------I------------------------------------------------------------------VS-AGI--------------------------------------------------------------------------------------------------------N-----SDT--------EY-TS----------------KSG------TSMSTPHVA----G-------AFLISLKFLQNNHEIYYFLCA------------------AA-V----FL----G-------DD-PSR-------------------------------------------------------------T---PLT--------------I---------------------RNMI-------SNE-------------------------AT------------------------------------------------------------------------R------DKVTDT-M--GTPNLLLH---------- 419
 420 ------W-------GLDRVDQRDLPL----------DDAY-YP----------EG-D-AT--------------------------G-V--NA--------------Y--------------------VVD---------------------------T--------------GIRY-D------H-------------V---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------EF------LDT-V-----AEPAP---------------YG-----------------------------------------------------------------------------------------D---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGILG----GAL----------------------------------------------------Y-------------------GV--AKN-V--NLLGV---RV---LNCE----------G-AG--Y------------LDD-------------------------------------L--------IYA--------------M-----------DY---VV----------ANGE------L-----P----------------------AV-----------------------------------------VSMSLG---------GDR---S---------------------P--------------------------VIDS-----AVGR-M--------FDA----GY-----F--------------------------------------------------------------------------------------F---------------VTSGG-NN--------DA---------D----A---CLQS---------------------------------------------------------------------------------------------------------------------------------------P-Q--G-A----PK---------------------A---FS---VA--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------TD-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---P--------------------CI------------------------------------------------N-----I------F-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------KS-TYY--------------------------------------------------------------------------------------------------------H-----SPT--------ST-AV----------------LSG------TSMACPHVA----G---------------------------A------------------GA-I----HL----G-------MN-PNL-------------------------------------------------------------L---PDE--------------V---------------------GAAL-------IAD-------------------------AT------------------------------------------------------------------------V------DRVIDAKEELGTPNVLLYT--------- 420
 421 ------------SWGLDRTDQRTLPLDDVFVP------EGDGA-------------------------------------------G-A--NV--------------F--------------------VLD---------------------------T--------------GITY-A------H-------------T---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AK-LF-------------------------------RDMVNPGNPSETDCD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GAT-----------------------------------------------------------------------YGV--AKK-V--NLWNT---RV---LNCF----------G-SG--P------------ASD-------------------------------------V--------AAG--------------M-----------TE---VA----------------D--------FG------D----------R-P--AA-----------------------------------------ISMSLS-YVDSV-------TID---------------------D-----------------------------------AATY---------CFEN----GV-----S--------------------------------------------------------------------------------------V---------------VTSSG-ND-DA-----DA------------------CFKS---------------------------------------------------------------------------------------------------------------------------------------P-QRNNRT-------------------------------IA---VG--A------------------------------T----------------------------DD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TR-AYF-----S--N--------Y-GPC-Q----------------------------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VS----------------------------------------------------------------------------------------------------------------------CDNNDLNGS-SV----------------KSG------TSMSCPHVA----G---------------------------V------------------AAIKLG----------------IKPEMS-----------------------------------------------------------------PGE--------------V---------------------KTTI-------LAD-------------------------------------------------------------------------------------------------STPGVVNDAKEE------EDTPNKLLYSAE------- 421
 422 ------ADQSIASWGLDRVDQRYLPLDDVFVP------EGDGA-------------------------------------------G-V--NV--------------Y--------------------VLD---------------------------T--------------GIRF-D------H-------------V---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------AAPFY-------------------------------DAIGNP--PEDGDCN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GEA-----------------------------------------------------------------------HGI--AKK-V--NLWSV---RV---LRCT----------G-SG--P------------RDA-------------------------------------I--------IEG--------------L-----------EY---VR----------------E--------NG------T----------L-P--GG-----------------------------------------ISMSIG-GSASE-------AYN---------------------D-----------------------------------VVNS---------VVLA----GF-----F--------------------------------------------------------------------------------------V---------------SVSAG-ND-GR--EHGDA------------------CLKS---------------------------------------------------------------------------------------------------------------------------------------P-ASAELA-------------------------------IA---CG--A------------------------------T----------------------------DS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VR-AEY-----S--N--------W-GVC-M----------------------------------------------------------------------N-----I------F-----------------A-----P-------------G-----------------DQ--------------------------------I------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------CTDDSPIST-GV----------------KSG------TSMACPHVA----G---------------------------V------------------CAVIVG----------------NDPTLT-----------------------------------------------------------------PSE--------------V---------------------WKKI-------QED-------------------------------------------------------------------------------------------------ATQGIVGDAKEE------DGTPNLLVYNSLN------ 422
 423 -----SW-------GLDRVDQRDLPL----------DGVF-KP----------AG-D-GA--------------------------E-V--DV--------------Y--------------------VVD---------------------------T--------------GIRY-D------H-------------E---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAH----------------------------------------------------------------------------------------------------------------------------------FF------FDVF-------GDSATDN------------DG-----------------------------------------------------------------------------------------D---C---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTIG----GTT----------------------------------------------------Y-------------------GI--AKK-V--TLWGV---RA---LNCD----------G-QA--S------------YSE-------------------------------------L--------LAS--------------L-----------EY---VA----------KHGT------T-----P----------------------SV-----------------------------------------INMSLA---------GDR---S---------------------I--------------------------SINL-----ALAS-L--------SHR----GF-----T--------------------------------------------------------------------------------------V---------------VVSAG-ND--------DT---------D----A---CDKS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-S----PE---------------------A---IT---VA--S------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------HD-------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SGY-----S--N--------Y-G---E--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------EK--------------------------------I------------------------------------------------------------------HS-DYS--------------------------------------------------------------------------------------------------------T-----SST--------ST-AV----------------LSG------TSMSAPHVS----G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 423
 424 ------W-------GLDRIDQRDLPL----------DGRM-DV----------KS-E-GD--------------------------G-A--HV--------------Y--------------------VVD---------------------------S--------------GIYT-D------H-------------D---------D--------------------------------F--------------------------------------G----------------------S------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------VA------ADF-I-----GGD-----------------GQ-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAV----GNT----------------------------------------------------Y-------------------GI--AKQ-A--SVYAL---RT---LDCS----------G-SG--Y------------KSD-------------------------------------S--------IAA--------------L-----------DW---VS----------ANGQ------K-----P----------------------GV-----------------------------------------VSMSLG---------GSV---S---------------------T--------------------------SQNT-----AVKN-C--------RNA----GY-----V--------------------------------------------------------------------------------------V---------------VVSAG-ND--------DG---------D----A---CDKS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----AE---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SYF-----S--N--------W-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------KS-CGI--------------------------------------------------------------------------------------------------------S-----SKT--------ST-ST----------------KSG------TSMSCPHVA----G---------------------------I------------------AA-V----MS----A-------SE-SDS-------------------------------------------------------------E---K----------------V---------------------YAAI-------ISN-------------------------AS------------------------------------------------------------------------S------GKVEDPET--GSPNLLAYL--------- 424
 425 -----SW-------GIDRVDQRDLPL----------DDSY-TT----------NG-D-GS--------------------------G-V--HV--------------Y--------------------VID---------------------------T--------------GVNV-M------H-------------D---------D--------------------------------L--------------------------------------A----------------------G------------------------------RVE----------------------------------------------------------------------------------------------------------------------------------VG------FDSRL-----DDPNDPQY------------GI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------SGTVA----GTT----------------------------------------------------Y-------------------GV--AKG-A--TIVGV---RA---LSCV----------G-FG--L------------LTD-------------------------------------I--------TAA--------------Y-----------EY---VT----------VNAI------K-----P----------------------AV-----------------------------------------ASMSLG---------GAK---N---------------------P--------------------------FVDR-----ATQG-M--------IDS----GV-----I--------------------------------------------------------------------------------------V---------------SVAAG-NS--------DT---------D----A---CTFS---------------------------------------------------------------------------------------------------------------------------------------P-A--N-V----PE---------------------A---IT---AA--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------ND-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---S--------------------CI------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------TS-IWY--------------------------------------------------------------------------------------------------------E-----DAT--------AT-YV----------------ASG------TSMACPHVS----G---------------------------A------------------AA-V----VL----G-------NN-PTF-------------------------------------------------------------T---VSH--------------V---------------------TAAL-------VNG-------------------------AT------------------------------------------------------------------------R------DKITDP-K--GSPNRLLYV--------- 425
 426 --------------GVEYVEQ-----DGVSRV------QAEAKIG-------DFS-W-----------------------------G-I--DR------------------------------------ID---------------------------H--------------GT-P-K------S--------------------------------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-DA-------------------------------------YTPHI------------------------------------SGMYAFEDCN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------CGTIG----GTT-----------------------------------------------------------------------LGV--ANQ-V--TVNAV---KV---MNCN----------G-IG--S------------SAS-------------------------------------I--------MAG--------------L-----------DY---VA----------------K--------YA------N----------SRM--DV-----------------------------------------VSMSIG-GGASP-------TQD---------------------Q-----------------------------------AVEA---------LIAD----GV-----P--------------------------------------------------------------------------------------V---------------AAAAG-NS-NQ-----DA------------------CYYS---------------------------------------------------------------------------------------------------------------------------------------P-ARVPTA-------------------------------IT---VG--A------------------------------T----------------------------NE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KR-APY-----S--N--------Y-GSC-L----------------------------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SN--------------------------------I------------------------------------------------------------------RS----------------------------------------------------------------------------------------------------------------------AGKLTDSTT-MV----------------MSG------TSMACPHVA----G---------------------------KSYILVFPQLQNSELIVVISAIALY----------------GTESRT-----------------------------------------------------------------TKE--------------G---------------------AKEM-------MTK-------------------------------------------------------------------------------------------------TTKRAIDDVA---------GSPNELLYV--------- 426
 427 DVASSSW-------GLDRIDQHNLPL---------------DDVF-------NIE-GDGE--------------------------G-V--TV--------------Y--------------------VLD---------------------------T--------------GIRG-S------H-------------E---------E--------------------------------F--------------------------------------G----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------HG--------------G-DYVDDGWN------------GI-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAA----GGI----------------------------------------------------H-------------------GI--ARK-A--NIVSI---RL---FNCA----------G-SG--S------------ASG-------------------------------------T--------IAG--------------I-----------DE---VT------------------RTA-----V------L----------P----AV-----------------------------------------MSMSFG---------FSV---T---------------------Q--------------------------AIDD-----AVAR-A--------VDA----GV-----V--------------------------------------------------------------------------------------A---------------AASAG-ND--------NS---------D----A---CLKS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----PK---------------------A---IT---TG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------DD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------F-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------VS-SST--------------------------------------------------------------------------------------------------------A-----SDK--------AI-AI----------------WSG------TSMAAPHVA----G---------------------------A------------------AA-I----LL-------------GKGIP-----------------------------------------------------------------PSD--------------V---------------------LEHL-------LED-------------------------AS------------------------------------------------------------------------Q------NVIYNTDF--LSPNRLLY---------- 427
 428 DVASSSW-------GLDRIDQHDLPL---------------DDAF-------NIE-GDGE--------------------------G-V--TV--------------Y--------------------VLD---------------------------T--------------GVRD-T------H-------------E---------E--------------------------------F--------------------------------------G----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------HG--------------G-DYVDDGWN------------GI-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAA----GGI----------------------------------------------------H-------------------GI--ARK-A--NIVSI---RL---FNCA----------G-SG--S------------ASG-------------------------------------T--------IAG--------------I-----------DE---VA------------------QNA-----V------L----------P----AV-----------------------------------------MSMSFR---------FLA---N---------------------Q--------------------------AIDD-----AVAR-A--------VDA----GV-----V--------------------------------------------------------------------------------------A---------------VAGAG-NE--------NM---------D----T---CLFS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----PK---------------------A---IT---AG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------DD-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------F-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------VS-SSS--------------------------------------------------------------------------------------------------------A-----SDT--------AI-AI----------------WSG------TSMATPHVA----G---------------------------A------------------AA-I----LL-------------GKGIA-----------------------------------------------------------------ASD--------------V---------------------LQQL-------LQD-------------------------AS------------------------------------------------------------------------Q------NVIYNTDF--LSPNRLLY---------- 428
 429 DAAPESW-------GLDRVDQRDLPL---------------DQSF-------EMQ-GDGT--------------------------G-V--TV--------------Y--------------------VLD---------------------------T--------------GIRE-T------H-------------E---------D--------------------------------F---------------------D----------------G----------------------G------------------------------RAR----------------------------------------------------------------------------------------------------------------------------------RD--------------PMDFVDDGWN------------GA-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAA----GGI----------------------------------------------------H-------------------GI--ARG-A--NIVSI---RL---FDCG----------G-FG--S------------ASD-------------------------------------I--------VSGNEYISSQELYPIKAI-----------DY---TT------------------ATA-----Q------R----------P----AV-----------------------------------------MSMSFG---------VVR---R---------------------N--------------------------AIDD-----AIEA-A--------SNS----QI-----I--------------------------------------------------------------------------------------P---------------VAAAG-NS--------DN---------D----A---CTFS---------------------------------------------------------------------------------------------------------------------------------------P-A--G-S----PK---------------------S---FT---VA--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------ND-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--S--------F-G---S--------------------CV------------------------------------------------Q-----L------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS-ASS--------------------------------------------------------------------------------------------------------A-----SDV--------AT-AT----------------WSG------TSMACPHVA----G---------------------------V------------------AA-V----HL-------------GNGVA-----------------------------------------------------------------PED--------------I---------------------RDRL-------VND-------------------------AS------------------------------------------------------------------------V------NKIYDSED--GTPNKLLYLG-------- 429
 430 ----ASW-------GLDRIDART-GL---------------DDQY-------NPK-YNGE--------------------------G-V--AV--------------Y--------------------VLD---------------------------T--------------GIRK-T------H-------------N---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------YG--------------Y-DAVDDDFV------------SD-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTTS----GTE----------------------------------------------------Y-------------------GV--AKL-T--NVYGS---RV---VNCL----------G-AG--P------------TDW-------------------------------------V--------IAG--------------M-----------DW---VL------------------AEG-----E------R----------P----AV-----------------------------------------VSMSLA---------YPR---S---------------------Q--------------------------AVDD-----AVAR-L--------TSG----GV-----T--------------------------------------------------------------------------------------V---------------VAGAG-ND--------DN---------D----A---CLRS---------------------------------------------------------------------------------------------------------------------------------------P-A--G-A----VD---------------------T---YT---AG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------ND-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VS-AGH--------------------------------------------------------------------------------------------------------L-----SDD--------DE-AT----------------MSG------TSMATPHVA----G---------------------------A------------------AA-V----VL----E-------EKSSRT-----------------------------------------------------------------PEE--------------V---------------------KARL-------TEL-------------------------ST------------------------------------------------------------------------K------DIVVDV-M--GSPNRLLY---------- 430
 431 ------W-------GCDRIDQRDLPL----------DDIM-NL----------YH-D-GS--------------------------G-A--HV--------------Y--------------------IID---------------------------T--------------GLRH-S------H-------------V---------E--------------------------------F---------------------E----------------P----------------------N------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------FH------FDY-E-----TR-GDVPP------------GD-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------GGSAA----GVT----------------------------------------------------V-------------------GI--GTS-A--RLYSV---RV---LNCM----------G-AG--S------------WAN-------------------------------------C--------IAG--------------C-----------DS---VT----------ATGT------R-----P----------------------GV-----------------------------------------SSLSLG---------GGA---H---------------------Q--------------------------GMDD-----AVTR-M--------IQA----GF-----V--------------------------------------------------------------------------------------V---------------SIAAG-ND--------NH---------D----A---CLNS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----EE---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------TD-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------RS-SYH--------------------------------------------------------------------------------------------------------L-----SDT--------SY-AT----------------LSG------TSMACPHVT----G---------------------------V------------------SA-V----HL----G-------AN-TCF-------------------------------------------------------------N---NTD--------------C---------------------KAKI-------LAE-------------------------AS------------------------------------------------------------------------V------DKVIDH----QSPDNLL----------- 431
 432 ------W-------GCDRIDQRNLPL----------DDQM-NL----------YG-D-GN--------------------------G-A--NI--------------Y--------------------IVD---------------------------T--------------GLRH-S------H-------------Q---------E--------------------------------Y---------------------Q---------------------------------------G------------------------------RAH----------------------------------------------------------------------------------------------------------------------------------FF------WDF-E-----YS-NR---------------GE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------GGTSA----GIT----------------------------------------------------V-------------------GI--ATS-A--SLYSV---RV---LNCM----------G-AG--S------------TTN-------------------------------------I--------VKG--------------C-----------DA---IT----------DGGS------K-----P----------------------GV-----------------------------------------ASLSLG---------GGA---S---------------------T--------------------------AMDS-----AVQR-M--------IDA----GY-----T--------------------------------------------------------------------------------------V---------------SIAAG-ND--------DA---------N----A---CNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----EA---------------------A---LT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------DD-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASY-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------RS-SYH--------------------------------------------------------------------------------------------------------L-----HDG--------SY-AV----------------LSG------TSMACPHVT----G---------------------------V------------------AA-V----HL----G-------AG-TCA-------------------------------------------------------------T---NAA--------------C---------------------KNKI-------ISE-------------------------GT------------------------------------------------------------------------S------GVVGDPGV--GSPNLLLY---------- 432
 433 --ATVEW-------GMDRTDQRSNNL----------DGVM-NL----------YA-T-GS--------------------------G-A--NA--------------Y--------------------ILD---------------------------T--------------GLRH-S------H-------------N---------E--------------------------------F---------------------D---------------------------------------N------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------YF------WDY-D-----SS-NN---------------GE-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------GGTVG----GNS----------------------------------------------------V-------------------GI--APD-T--LLYSV---RV---LNCQ----------G-SG--L------------ISN-------------------------------------M--------VDG--------------L-----------DE---IV----------ARGN------T-----P------S----------R----SV-----------------------------------------VSMSVG---------AGA---S---------------------L--------------------------SQDN-----AVQR-V--------IDD----GY-----T--------------------------------------------------------------------------------------A---------------SIAAG-NE--------DQ---------D----A---CNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----ED---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------ND-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AGF-----S--N--------W-G---S--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------V------------------------------------------------------------------RS-AWY--------------------------------------------------------------------------------------------------------T-----CDS--------CY-ET----------------ISG------TSMACPHVS----G---------------------------V------------------AA-V----HL----G-------AG-TCN-------------------------------------------------------------D---NAS--------------C---------------------RNKI-------VA--------------------------------------------------------------------------------------------------------------LDSTI--GA---------------- 433
 434 ------W-------GCDRTDQRNLPL----------NGVA-NF----------NG-D-GS--------------------------G-T--HV--------------Y--------------------IID---------------------------T--------------GLRH-T------H-------------V---------E--------------------------------F---------------------G---------------------------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------FF------FDF-E-----PL-NQ---------------GD-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------GGTSV----GID----------------------------------------------------V-------------------GI--APA-A--SVYSV---RV---MNCN----------G-IG--L------------TTN-------------------------------------I--------VDG--------------I-----------DA---VA----------NGGT------M-----P----------------------GA-----------------------------------------ANLSLG---------GGP---S---------------------P--------------------------AMDD-----ATTR-L--------TEA----GY-----T--------------------------------------------------------------------------------------T---------------AVAAG-NS--------NE---------D----A---CDGS---------------------------------------------------------------------------------------------------------------------------------------P-S--R-E----ST---------------------S---IT---VG--A------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------QD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---T--------------------CL------------------------------------------------E-----I------F-----------------A-----P-------------G-----------------SS--------------------------------V------------------------------------------------------------------RS-SYN--------------------------------------------------------------------------------------------------------T-----CDS--------CY-AT----------------LSG------TSMAAPHVC----G---------------------------V------------------AA-V----LL----S-------GD-QCT-------------------------------------------------------------D---NTS--------------C---------------------RTRI-------EAD-------------------------AT------------------------------------------------------------------------E------DVVSDPGI--GSPNKLLY---------- 434
 435 ------W-------GCDRTDQRNLPL----------DGVA-AF----------ND-N-GA--------------------------G-T--HV--------------Y--------------------IID---------------------------T--------------GLRH-T------H-------------D---------E--------------------------------F---------------------N---------------------------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------FF------FDF-E-----PA-NQ---------------GD-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------GGTSV----GNS----------------------------------------------------V-------------------GI--ATA-A--SVYSV---RV---LNCN----------G-AG--L------------TSN-------------------------------------I--------VDG--------------C-----------DA---IV----------AGGQ------K-----P----------------------GT-----------------------------------------CNMSIG---------GGA---S---------------------I--------------------------LLDN-----AVAS-L--------TSD----GY-----V--------------------------------------------------------------------------------------V---------------SVSAG-ND--------DT---------D----A---CNQS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-E----ET---------------------S---IT---TG--S------------------------------T-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------DD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SGF-----S--N--------Y-G---T--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SL--------------------------------I------------------------------------------------------------------RS-SYH--------------------------------------------------------------------------------------------------------T-----ADN--------AY-TI----------------MSG------TSMASPHVV----G---------------------------V------------------AA-A----ML----G-------GG-VCS-------------------------------------------------------------D---HAS--------------C---------------------KNNI-------LAV-------------------------GT------------------------------------------------------------------------A------DVVGSPGI--GSPNLLLY---------- 435
 436 ------W-------GVDRIDQRDLPL----------NDDM-TI----------NS-Y-GK--------------------------D-V--NV--------------Y--------------------IID---------------------------T--------------GINP-D------H-------------E---------D--------------------------------F--------------------------------------G----------------------G------------------------------RGM----------------------------------------------------------------------------------------------------------------------------------PV------MDF-V-----EPDNG---------------AI-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SNT----------------------------------------------------Y-------------------GI--ARE-A--NLYGI---RI---LSCS----------G-SG--A------------VSS-------------------------------------S--------VAA--------------L-----------DW---VA----------VEGK------R-----P----------------------AV-----------------------------------------ASMSYG---------GFY---S---------------------P--------------------------TEMR-----AAER-A--------KEM----GV-----V--------------------------------------------------------------------------------------L---------------VAAAG-NS--------ND---------D----A---CFSS---------------------------------------------------------------------------------------------------------------------------------------P-A--G-S----PD---------------------V---IT---VG--S------------------------------S-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------QD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--C--------Y-G---R--------------------CV------------------------------------------------Q-----L------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------TS-LAH--------------------------------------------------------------------------------------------------------D-----SND--------GT-KT----------------YSG------TSMACPHVA----G---------------------------I------------------AA-V----LL----G-------QG-YSA-------------------------------------------------------------Q---Q----------------V---------------------YEKI-------VSS-------------------------AT------------------------------------------------------------------------F------GKIANP-N--GTPNLLAYL--------- 436
 437 TQAVGSW-------GLDRIDARSTLYGSVR------DGTY-TP----------FV-T-GA--------------------------G-V--DV--------------Y--------------------VID---------------------------S--------------GILE-T------H-------------E---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------QSFCASDLFSF-I------G-GG---------------NV-----------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--ASG-V--TLIGV---KV---INCF----------G-SG--S------------TAG-------------------------------------V--------IEG--------------V-----------NW---VI----------EQATRLKARRR-----P----------------------SV-----------------------------------------ASISIT---------APY---S---------------------R--------------------------ALNE-----AVDA-M--------VDA----GV-----E--------------------------------------------------------------------------------------T---------------AVAAG-ND--------NT---------N----A---CDYS---------------------------------------------------------------------------------------------------------------------------------------P-A----------S---------------------T---LS---IG--A------------------------------P-----------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------WP-------P-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H---F-----F--H--------Y-G---P--------------------CI------------------------------------------------D-----I------F-----------------S-----P-------------G-----------------AY--------------------------------T------------------------------------------------------------------VS-TWI--------------------------------------------------------------------------------------------------------G----ASNR--------AT-ET----------------LSG------TSMACAHVA----G---------------------------A------------------LA-L----YL----T-------ED-ELM-------------------------------------------------------------H---QSTANVVTDPGALALYLT---------------------EEEL-------MHQ-------------------------ST------------------------------------------------------------------------A------NVVTDPGP--GSPNRFLY---------- 437
 438 --------------------GSDVTWGLDRIDQREKLTDAGVVGY-------NPP-GHGD--------------------------GVS---V--------------Y--------------------IMD---------------------------T--------------GIDK-N------Q-------------Q---------E--------------------------------FGK--------------RRHSFY-----DGVNSKP-SPNVCN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TH-V-----------------------AGIVG----SKT-----------------------------------------------------------------------YGV--ANQ-A--ELYSV---TV---LNCN----------N-AG--T------------LTD-------------------------------------I--------IGG--------------L-----------D----------------------------------YIATHG----------TKP--GV-----------------------------------------IVMALSG-VF---------------------------VEALNQ------------------------------------AIAN---------VEAE----GY-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS-------------------AD-----DACLYS---------------------------------------------------------------------------------------------------------------------------------------P-GSSEKA-------------------------------IT---VA--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TANDDHATTY-----S--N--------Y-GEC-I----------------------------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------NY--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTTGSDNKNPPL-------------------RSG------TSMACPFIA----G---------------------------I------------------AAIH----L-Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KN-PDLTPAEVKDIILSSGTKDTVYGTAIDN------------------ 438
 439 ------W-------GLDEIDLT--PG---------------NGIY-------DPP-GDGS--------------------------G-K--TV--------------Y--------------------IID---------------------------S--------------GIYP-K------H-------------K---------D--------------------------------W--------------------------D-TSPKLL-SNHVTGKKKLG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D---C---------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVG----SKT-----------------------------------------------------------------------YGV--AKK-A--QLSAV---VV---FDCD----------G-SG--T------------WGR-------------------------------------V--------ISG--------------L-----------NT---IV--------------------N-----E------G----------VPD--SI-----------------------------------------INLSLA---------GSYAQAV--------------------VD--------------------------ALAD-----ANDA-----------------GF-----L--------------------------------------------------------------------------------------I---------------VTAAG-NA--------NV---------DGCTML----------------------------------------------------------------------------------------------------------------------------------------------P-ANST-D---------------------------V---IA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------SD-------G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YV-WPG-----S--N--------Y-GP-----------------------CV------------------------------------------------D-----M------Y-----------------A-----P-------------G-----------------AG--------------------------------I------------------------------------------------------------------LS-LDI-------------------------------------------------------------------------------------------------------------QNPS--------ST-TV----------------KTG------TSMASPEVA----G---------------------------M------------------AA-V----LW----S-------LNPTYT-----------------------------------------------------------------NAQ--------------I---------------------RDLI-------FNDAIHDEVLGL----------------------------------------------------------------------------------------------------------------------------- 439
 440 IQSKPVW-------GLDHIDGVDDDM------------------Y-------EYA-YTGL--------------------------G-V--DA--------------Y--------------------IID---------------------------T--------------GILA-S------H-------------A---------D--------------------------------L---------------------E----------------G-----------------------------------------------------RVA----------------------------------------------------------------------------------------------------------------------------------SC----------------ISFTGEAC------------GF-----------------------------------------------------------------------------------------D---L---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKQ-V--SLHDV---KV---LNVN----------G-TG--S------------YAN-------------------------------------V--------IAA--------------V-----------DH---VT--------------KIKQENS-----T------R----------K----IV-----------------------------------------MNLSLG---------GGI---S---------------------T--------------------------ALNT-----AINS-A--------VDQ----GI-----A--------------------------------------------------------------------------------------V---------------AVAAG-NN--------NQ---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SK---------------------A---LT---VG--A------------------------------M-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------TN-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------VS-L----------------------------------------------------------------------------------------------------------S-----STG--------GT-ST----------------KAG------TSMASPHVA----G---------------------------V------------------AALY----LE----A-------GR--------------------------------------------------------------------------------------P---------------------VSKI-------VAD-------------------------AA------------------------------------------------------------------------T------DRL-SDLS--SSSNSLVSTALL------ 440
 441 VQAGPTW-------GLDVIDGSDDDK------------------Y-------TYS-FTGK--------------------------G-V--DA--------------Y--------------------ILD---------------------------T--------------GI-A-A------H-------------S---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RVA----------------------------------------------------------------------------------------------------------------------------------SC----------------ISFANEAC------------GS-----------------------------------------------------------------------------------------D---G---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKE-V--TLHDV---KV---LNAM----------G-RG--T------------YSG-------------------------------------V--------IAA--------------I-----------DH---IS--------------KIKRENT-----S------K----------K----MV-----------------------------------------INMSLS---------GGT---N---------------------S--------------------------ALDN-----AINS-A--------ANL----GI-----V--------------------------------------------------------------------------------------V---------------VVAAG-NA--------NA---------D----A---CNFS---------------------------------------------------------------------------------------------------------------------------------------P-S--S-A----AG---------------------A---LA---VG--A------------------------------M-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------SN-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-TVF-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------VS-L----------------------------------------------------------------------------------------------------------S-----TTG--------GT-ST----------------KAG------TSMASPHVA----G---------------------------V------------------AALY----LE----A-------GR--------------------------------------------------------------------------------------S---------------------ASNI-------QTD-------------------------AV------------------------------------------------------------------------A------GKL-SNLS--GSPNKL------------ 441
 442 VQTNPPW-------GLDITDGKDDNR------------------F-------TYT-YTGQ--------------------------G-V--DV--------------Y--------------------VLD---------------------------T--------------GIQA-N------H-------------P---------D--------------------------------L---------------------E----------------G-----------------------------------------------------RVD----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYTNEAC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKK-V--SLHDV---KV---LDRR----------G-SG--S------------FSG-------------------------------------V--------IAG--------------I-----------DY---VA--------------QIKKTDP-----S------R----------K----TV-----------------------------------------LNMSLG---------GGR---S---------------------T--------------------------ALNN-----AVNS-A--------ATS----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NR---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SG---------------------A---LV---VG--S------------------------------I-----------------------------E------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------NN-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSW-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----A-------------G-----------------SG--------------------------------I------------------------------------------------------------------LS-L----------------------------------------------------------------------------------------------------------S-----RTG--------GV-TT----------------KSG------TSMAAPHVA----G---------------------------V------------------AALY----LQ----V-------GR--------------------------------------------------------------------------------------N---------------------PNTI-------TSD-------------------------AL------------------------------------------------------------------------K------NRV-TRTR--GSDNKL------------ 442
 443 VQINPTW-------GLDITDGEDDSL------------------Y-------TYA-YTGQ--------------------------G-V--NA--------------Y--------------------ILD---------------------------T--------------GIQA-N------H-------------P---------E--------------------------------F---------------------Q----------------G-----------------------------------------------------RVE----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYTGEVC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKK-V--SLHDV---KV---LDRR----------G-SG--S------------FSG-------------------------------------V--------IAG--------------I-----------DY---VA--------------QIKKTDP-----S------R----------K----TV-----------------------------------------LNMSLG---------GGR---S---------------------T--------------------------ALNN-----ALDS-A--------AAS----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NH---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SG---------------------A---LV---VG--S------------------------------I-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------NN-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSW-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----A-------------G-----------------SG--------------------------------I------------------------------------------------------------------LS-L----------------------------------------------------------------------------------------------------------S-----RTG--------GV-TT----------------KSG------TSMAAPHVA----G---------------------------V------------------AALY----LQ----A-------GR--------------------------------------------------------------------------------------N---------------------PNTI-------TSD-------------------------AL------------------------------------------------------------------------K------NRV-TRTR--GSHNKL------------ 443
 444 VQMNPTW-------GLDITDGQDNNR------------------Y-------TYT-YTGR--------------------------G-V--HV--------------Y--------------------ILD---------------------------T--------------GIQA-N------H-------------R---------D--------------------------------F---------------------E----------------R-----------------------------------------------------RVK----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYTGEAC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKK-V--FLHDV---KV---LNRR----------G-SG--S------------YSG-------------------------------------V--------IAG--------------I-----------DY---VA--------------RIKRGNP-----R------R----------K----MV-----------------------------------------LNMSLG---------GGR---N---------------------I--------------------------SLNK-----AINA-A--------AAS----GV-----M--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NQ---------N----A---CNFS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SG---------------------A---LA---VG--S------------------------------I-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------NN-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSW-----S--N--------W-G---R--------------------CV------------------------------------------------N-----I------F-----------------A-----P-------------G-----------------SG--------------------------------I------------------------------------------------------------------VS-L----------------------------------------------------------------------------------------------------------S-----RTG--------GT-ST----------------KSG------TSMASPHVA----G---------------------------V------------------AALY----LQ----A-------GR--------------------------------------------------------------------------------------R---------------------TGFI-------VPD-------------------------AV------------------------------------------------------------------------T------SQL-TDVR--GALNR------------- 444
 445 VQIDPTW-------GLDIVDGTIDRR------------------Y-------NYT-YTGL--------------------------G-V--EV--------------Y--------------------ILD---------------------------T--------------GIQA-N------H-------------S---------E--------------------------------L---------------------E----------------G-----------------------------------------------------RVE----------------------------------------------------------------------------------------------------------------------------------SC----------------VSFTPEEC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKT-V--SLHDV---KV---LNAK----------G-SG--S------------YSA-------------------------------------V--------IAG--------------V-----------DY---VT--------------QIKMSDP-----S------R----------K----IV-----------------------------------------INMSLG---------GGI---S---------------------T--------------------------SFNN-----AITS-A--------ADS----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------DD---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SG---------------------V---LA---VG--S------------------------------I-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------DK-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSW-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SG--------------------------------I------------------------------------------------------------------LS-L----------------------------------------------------------------------------------------------------------S-----QSN--------GT-TT----------------KSG------TSMAAPHVA----G---------------------------V------------------AALY----LQ----A-------GR--------------------------------------------------------------------------------------S---------------------TDSI-------ASD-------------------------AL------------------------------------------------------------------------E------NGI-SDVK--ESSNRL------------ 445
 446 IQNNPTW-------GLDLVDGSDDNR------------------Y-------TYT-YTGR--------------------------G-V--DV--------------Y--------------------IVD---------------------------T--------------GIQA-N------H-------------P---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RVR----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYTGESC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----SKT----------------------------------------------------Y-------------------GV--AKQ-V--SLHDV---KV---LNQR----------G-SG--S------------YSG-------------------------------------V--------IAG--------------V-----------DY---VT--------------KIKENNR-----S------R----------R----IV-----------------------------------------INMSLA---------GGV---F---------------------A--------------------------RLNS-----AIDS-A--------AAQ----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GA---------D----A---CNAS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----SG---------------------A---LV---VG--A------------------------------I-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------RN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-TSW-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------TG--------------------------------I------------------------------------------------------------------LS-T----------------------------------------------------------------------------------------------------------A-----KTG--------GT-ST----------------KSG------TSMASPHVA----G---------------------------V------------------AALY----LE----S-------GR--------------------------------------------------------------------------------------N---------------------TNSI-------TSD-------------------------AR------------------------------------------------------------------------T------GQL-GNLE--GSPNRL------------ 446
 447 VQTDPTW-------GLDIIDGQADNL------------------Y-------SYA-FTGQ--------------------------G-V--DV--------------Y--------------------VLD---------------------------T--------------GIQA-N------H-------------P---------D--------------------------------L---------------------E----------------G-----------------------------------------------------RVE----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYSGEEC------------GS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------TGTVG----SKT----------------------------------------------------Y-------------------GV--AKK-A--SLHDV---KV---LNQN----------G-SG--S------------YVG-------------------------------------V--------IAG--------------I-----------DY---VA--------------QINNADP-----S------R----------N----IV-----------------------------------------MNLSLG---------GGF---S---------------------P--------------------------ALNS-----AINS-A--------ADS----GV-----V--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NE---------D----A---CNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----ER---------------------A---LV---VG--S------------------------------I-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------SN-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SVW-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SG--------------------------------I------------------------------------------------------------------LS-L----------------------------------------------------------------------------------------------------------S-----PNS--------GT-ST----------------KWG------TSMASPHVA----G---------------------------V------------------AALY----LQ----A-------RK--------------------------------------------------------------------------------------S---------------------TDFI-------TSD-------------------------GL------------------------------------------------------------------------E------DQLSSNLE--GSPN-------------- 447
 448 IQRNPTW-------GLDITDGQDDNR------------------Y-------NYT-YTGR--------------------------G-V--DV--------------Y--------------------ILD---------------------------T--------------GIYA-N------H-------------P---------E--------------------------------L---------------------E----------------G-----------------------------------------------------RVK----------------------------------------------------------------------------------------------------------------------------------SC----------------VSYTGEAC------------GS-----------------------------------------------------------------------------------------D---L---------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVG----SKT----------------------------------------------------Y-------------------GV--AKK-V--SLHDV---KV---LDQY----------G-GG--T------------WSG-------------------------------------V--------IAG--------------V-----------DY---VA--------------KIKKRNP-----R------R----------K----II-----------------------------------------INMSLG---------GFR---N---------------------R--------------------------PMNK-----AVRA-A--------ARA----KV-----V--------------------------------------------------------------------------------------V---------------VVSAG-NY--------DD---------N----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--S-A----SG---------------------A---LV---VG--S------------------------------F-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------------------------------------------------------------------------------------FN-------Y-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SWF-----S--N--------W-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SD--------------------------------V------------------------------------------------------------------LS-L----------------------------------------------------------------------------------------------------------D-----SNG--------GT-VT----------------YSG------TSMASPHVA----G---------------------------V------------------AALY----LQ----A-------GR--------------------------------------------------------------------------------------K---------------------IRSV-------VTD-------------------------AM------------------------------------------------------------------------R------KQL-FDVK--GSTNR------------- 448
 449 KTLDSCTEQSGATWGLVRTCSQDM---SSSSY-YYNP-NCAGS-------------------------------------------G-V--DV--------------Y--------------------IID---------------------------T--------------GIEV-Y------H-------------S---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-GR-------------------------------------SEWGSD----------------------------FVDSGNSPGT----DLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVM----SST-----------------------------------------------------------------------WGL--AKK-A--TSVAV---RV---LDAD----------G-SG--Y------------VSG-------------------------------------V--------VSG--------------I-----------SW---VA----------------EQH------QS------R----------GRK--SV-----------------------------------------ANLSLG-GGYSS-------TLN---------------------E-----------------------------------AVDA---------AVSA----GV-----H--------------------------------------------------------------------------------------M---------------VVAAG-NE-LT-----DA------------------CYRS---------------------------------------------------------------------------------------------------------------------------------------P-ASTQYG-------------------------------IT---VA--A------------------------------S----------------------------DS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF-AYF-----S--N--------Y-GTC-V----------------------------------------------------------------------D-----I------I-----------------A-----P-------------G-----------------VY--------------------------------I------------------------------------------------------------------SS----------------------------------------------------------------------------------------------------------------------TWLNGGSA---S----------------LSG------TSMAAPHVA----G---------------------------V------------------VAKILS-----------------CTDYS-----------------------------------------------------------------PSE--------------M---------------------K--------------------------------------------------------------------------------------------------------------------------------------------------- 449
 450 -------DQLEATWGLVRTVERDL---LLDGI-YHYQ-GGDGE-------------------------------------------G-V--DA--------------Y--------------------IID---------------------------T--------------GIYT-E------H-------------S---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------AKWGVD----------------------------TVDT-PSPET----DEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVM----SDA-----------------------------------------------------------------------WGL--AKK-A--TAIAV---KV---LSRS----------G-SG--S------------TAG-------------------------------------V--------IEG--------------V-----------EW---TG----------------QQH------SG------N----------NKK--SV-----------------------------------------ANMSLG-GGRSD-------AMN---------------------E-----------------------------------AVKA---------VVEA----GV-----V--------------------------------------------------------------------------------------M---------------VVAAG-NE-GW-----EA------------------CNVS---------------------------------------------------------------------------------------------------------------------------------------P-ASEPTA-------------------------------IT---VG--C------------------------------S----------------------------DN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DF-CFF-----S--N--------Y-GTC-M----------------------------------------------------------------------D-----I------I-----------------A-----P-------------G-----------------QD--------------------------------V------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------AWIGGQFAD-NT----------------ISG------TSMSAPHIA----G---------------------------I------------------VAKYMS---R------------QSSVPS-----------------------------------------------------------------PEE--------------V---------------------KDFL-------QTT-------------------------------------------------------------------------------------------------STKDKINQ-IP--------SNSDTLNYLGFMDCGGG- 450
 451 KATKTCNEQLFAEWGLVRTTERTL---NLSGV-YRYA-DGTGE-------------------------------------------G-V--DA--------------Y--------------------VLD---------------------------T--------------GILL-S------H-------------K---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-GR-------------------------------------AVWGTD----------------------------TVEN-PSPKT----DLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIM----GDR-----------------------------------------------------------------------FGL--AKK-A--TAVAV---RV---LDAD----------G-SG--T------------LKM-------------------------------------V--------MDG--------------I-----------NW---VA----------------NNHNEKMKKNK------N----------SKG--SV-----------------------------------------ANMSLG-GAYSK-------TEN---------------------E-----------------------------------AVAA---------AVKS----GI-----S--------------------------------------------------------------------------------------F---------------VVAAG-NE-KA-----DA------------------CDTS---------------------------------------------------------------------------------------------------------------------------------------P-ASEPTA-------------------------------IT---VG--A------------------------------T----------------------------NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YQ-WEG-----T--N--------Y-GKC-V----------------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------EG--------------------------------I------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------DWIYSDYSI-TT----------------ITG------TSMASPHVA----G---------------------------V------------------VAKYLS---S------------LSSTPS-----------------------------------------------------------------PSA--------------V---------------------ASWL-------DSA-------------------------------------------------------------------------------------------------STKDKIAL-APWARL---AGTPNKLVYLS--EC---- 451
 452 -------DQRNAEWGLVRTTERAL---RLDGI-YSYARDATGD-------------------------------------------G-V--DA--------------Y--------------------VID---------------------------T--------------GIYL-E------H-------------T---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-GR-------------------------------------ATWGID----------------------------TIDV-PSPET----DEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----GAM-----------------------------------------------------------------------YGI--AKD-V--NLIAV---KV---LNRD----------G-AG--S------------TDA-------------------------------------I--------IDG--------------V-----------RW---VE----------------DNHLTKKTKST------N----------AKG--SV-----------------------------------------ANMSLG-GGFSV-------AMN---------------------R-----------------------------------AVES---------AISS----GI-----T--------------------------------------------------------------------------------------F---------------IAAAG-NDYGT-----DA------------------CLVS---------------------------------------------------------------------------------------------------------------------------------------P-ASVDKV-------------------------------IT---VG--C------------------------------T----------------------------TN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QF-CVF-----S--N--------A-GTC-V----------------------------------------------------------------------N-----I------L-----------------A-----P-------------G-----------------EG--------------------------------I------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------CGIDGPFAD-IT----------------LSG------TSMSSPHVA----G---------------------------V------------------AAKYIS---S------------LKSTPT-----------------------------------------------------------------PAE--------------V---------------------KKWL-------DMN-------------------------------------------------------------------------------------------------ATKDKITE-IP-------ADTPNKLLF---------- 452
 453 -----------------------------------------GD-------------------------------------------N-V--DV--------------Y--------------------VFD---------------------------T--------------GIYL-Q------H-------------K---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------AKWGTD----------------------------TIDS-PSPLT----DQH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-A-----------------------AGTIG----GAI-----------------------------------------------------------------------FGI--AKM-A--NLIAV---KV---LNRR----------G-KG--S------------TKS-------------------------------------I--------IKG--------------A-----------VW---VE----------------DQHLKKMSKIT------R----------ANG--SV-----------------------------------------ANMSIG-VRRSH-------SVN---------------------R-----------------------------------AVES---------LIGS----GV-----T--------------------------------------------------------------------------------------T---------------VVAAG-NE-FD-----DA------------------CKLS---------------------------------------------------------------------------------------------------------------------------------------P-ASVKTA-------------------------------IT---VG--C------------------------------T----------------------------TS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RF-CVY-----S--N--------V-GKC-V----------------------------------------------------------------------N-----I------L-----------------A-----P-------------G-----------------QG--------------------------------I------------------------------------------------------------------AS----------------------------------------------------------------------------------------------------------------------CGIRGPVSV-TT----------------KSG------TSFSVAHVT----G---------------------------V------------------VAKYIS---S------------LNSLPT-----------------------------------------------------------------PAE--------------V---------------------KKWI-------EKN-------------------------------------------------------------------------------------------------AT----------------------------------- 453
 454 SSAQNCLSQSGAIWNLQRINAQ-----AISGMDGKYTYGTEAA-------------------------------------------D-V--DA--------------Y--------------------IVD---------------------------T--------------GILT-T------H-------------Q---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNGR-------------------------------------ALWGAN----------------------------FADS---QDT----DCN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----GKT-----------------------------------------------------------------------VGI--ARG-V--TLYAV---KV---LGCD----------G-SG--T------------TNG-------------------------------------V--------ISG--------------I-----------QW---VA----------------ENA------RK------R----------GRK--SV-----------------------------------------ANMSLG-GGYSS-------SLN---------------------R-----------------------------------AVAS---------VVDA----GV-----P--------------------------------------------------------------------------------------F---------------AVAAG-NE-DQ-----NA------------------CNTS---------------------------------------------------------------------------------------------------------------------------------------P-ASEAKA-------------------------------IT---VG--A------------------------------TYY------------------------SGNF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DIRASF-----S--N--------W-GTC-V----------------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------QS--------------------------------I------------------------------------------------------------------KS----------------------------------------------------------------------------------------------------------------------AWIGSNSAY-NT----------------ISG------TSMASPHVC----G---------------------------V------------------AALTFS----------------ANPSYS-----------------------------------------------------------------AAD--------------V---------------------KSKI-------LAD-------------------------------------------------------------------------------------------------STDNVIDLRCTRSGC---SSTPNKLLYSARC------ 454
 455 ------W-------GLVRTSSRA----DNV------DYDT-EMYW-------IDA-DDGS--------------------------G-V--DS--------------Y--------------------IVD---------------------------T--------------GINI-A------H-------------V---------D--------------------------------Y--------------------------------------G----------------------G------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------HG------FTAPGIG-EGNDDL-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GST----------------------------------------------------Y-------------------GV--AKN-T--NLIAV---KV---MNRF----------G-SG--L------------TTD-------------------------------------I--------VAG--------------I-----------EY---VT----------TQHQ-AS---T-----S------K----------K----SV-----------------------------------------MNISLG-------S-AGD---S---------------------P--------------------------AMNG-----AVEA-A--------IAA----GV-----H--------------------------------------------------------------------------------------A---------------AIAAG-NS--------NA---------D----A---CNFS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----ED---------------------A---LT---TA--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------AD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-ASF-----T--N--------Y-G---T--------------------CV------------------------------------------------D-----V------I-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----SNT--------AT-NS----------------ISG------TSMAAPHIC----G---------------------------W------------------VARY----LS----T-------FE-DGA-------------------------------------------------------------PPT-PLE--------------V---------------------KDYL-------QAN------------------------GGT------------------------------------------------------------------------R----DVINLEAPKD--TTPNII------------ 455
 456 ------W-------GLSRVSSRMTPNYEHS------TYQ-----Y-------VDS-QDGS--------------------------G-V--EV--------------Y--------------------VLD---------------------------T--------------GINV-E------H-------------T---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------HG------FTAPGIT-EGDDDL-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGSVG----GTK----------------------------------------------------Y-------------------GV--AKG-V--KLIAV---KV---LGFF----------G-FG--S------------NTD-------------------------------------I--------ISG--------------I-----------EY---VH----------QQH---T---A-----G------S----------K----TV-----------------------------------------MNLSLG-------G-AGS---S---------------------P--------------------------AMEA-----ALQA-A--------IDA----GV-----H--------------------------------------------------------------------------------------A---------------VVAAG-NS--------NA---------D----A---CSFS---------------------------------------------------------------------------------------------------------------------------------------P-A--H-L----AD---------------------A---IT---VA--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------KD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-YSS-----S--N--------H-G---T--------------------CV------------------------------------------------D-----V------I-----------------A-----P-------------G-----------------EN--------------------------------I------------------------------------------------------------------PS-TYI--------------------------------------------------------------------------------------------------------G-----GPD--------AT-AT----------------LTG------TSMAAPHVA----G---------------------------W------------------VARH----LS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 456
 457 TSGATIW-------GLSRTSSRPLPEFTGA------TYD-----W-------TDE-DDGS--------------------------G-V--NA--------------Y--------------------VID---------------------------T--------------GIYL-G------H-------------Q---------D--------------------------------Y--------------------------------------A----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------HG------FTAPGIS-EGDDDL-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----GTT----------------------------------------------------Y-------------------GV--AKG-V--NLIAV---KV---LNRA----------G-SG--S------------TTD-------------------------------------V--------VSG--------------V-----------EY---VA----------NQH---N---S-----G------D----------K----TI-----------------------------------------MNLSLG-------M-TGT---S---------------------I--------------------------ALNE-----ALTA-A--------IAA----GA-----N--------------------------------------------------------------------------------------A---------------AVAAG-NS--------NA---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--Q-V----ET---------------------A---LT---TV--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------AD-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-PTF-----T--N--------Y-G---T--------------------CC------------------------------------------------D-----I------I-----------------A-----P-------------G-----------------NN--------------------------------I------------------------------------------------------------------LS-TYI--------------------------------------------------------------------------------------------------------G-----GPT--------AT-AS----------------LSG------TSMAAPHVA----G---------------------------W------------------VARY----LS----S----------QSS-------------------------------------------------------------APT-PAA--------------V---------------------KTAL-------QST-------------------------AT------------------------------------------------------------------------P----DVITL-GSKV--GTPNYLVY---------- 457
 458 ------W-------GLSRISSRQQPDYKTA------TYK-----Y-------EDA-SDGH--------------------------G-V--EV--------------Y--------------------VVD---------------------------T--------------GIYV-Q------H-------------N---------D--------------------------------F--------------------------------------E----------------------G------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------HG------FTAPGIT-EGDDDL-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIG----GAE----------------------------------------------------H-------------------GV--AKK-A--SLVAV---KV---LNSF----------G-SG--M------------TSD-------------------------------------L--------VAG--------------M-----------EY---IV----------QQHA-AN---N-----N------S----------K----SV-----------------------------------------MNLSLG-------M-SGS---A------------------------------------------------VVDE-----ALEA-S--------IRA----GV-----S--------------------------------------------------------------------------------------A---------------AVVSG-NS--------NS---------D----A---CMFS---------------------------------------------------------------------------------------------------------------------------------------P-G--R-V----ET---------------------A---LT---AA--A------------------------------M-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------TD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-LES-----S--N--------Y-G---T--------------------CI------------------------------------------------N-----I------L-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------KS-TFI--------------------------------------------------------------------------------------------------------G-----SPD--------AT-AV----------------MSG------SSLAGPHAA----G---------------------------W------------------MARY----MS----A-------FD-LSL---------------------------------------------------------------T-PAE--------------V---------------------MEAL-------EEI-------------------------ST------------------------------------------------------------------------K----DVLNIPPGKE--ETPNRLVY---------- 458
 459 ------W-------GLSRISSRLKPLYADA------TYK-----Y-------AVA-GEG-----------------------------V--DV--------------Y--------------------IVD---------------------------T--------------GIFV-Q------H-------------E---------D--------------------------------F--------------------------------------H----------------------G------------------------------RAR----------------------------------------------------------------------------------------------------------------------------------HG------YTAPGIT-EGNKDL-------------------------------------------------------------------------------------------------------------------------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAA----SST----------------------------------------------------Y-------------------GV--AKE-A--ALVAV---KV---MDAA----------G-SG--L------------VSD-------------------------------------A--------VAG--------------I-----------EY----V----------YKEH-VK---G-----K------R----------K----SV-----------------------------------------MNLSFG-------V-SEP---N---------------------L--------------------------ALER-----AVTA-A--------VES----GI-----N--------------------------------------------------------------------------------------A---------------AVAAG-NN--------AG---------D----A---CLVT---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----QS---------------------A---IT---VT--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------SD-------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ADY-----A--N--------Y-G---P--------------------CV------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------LS-TYI--------------------------------------------------------------------------------------------------------G-----SRD--------AT-AV----------------LSG------TSMAAPHVA----G---------------------------W------------------VARY----LS----E----------PRD-------------------------------------------------------------DIPIPRQ--------------V---------------------KAAL-------QSS-------------------------ST------------------------------------------------------------------------K----G--VLYPVDG---TLDLLVY---------- 459
 460 ------------------ISHRNRLT----------LSTFQKYIY-------Y-S-GGGE--------------------------G-V--TA--------------Y--------------------VID---------------------------T--------------GINI-E------H-------------V---------E--------------------------------F---------------------E----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPKNDV------------DK-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----SRK----------------------------------------------------Y-------------------GV--AKN-A--QLVAV---KV---LGSN----------G-SG--T------------MSD-------------------------------------V--------IAG--------------V-----------LW---AAEQAAIDAEKAAREVATTGKTK-----H------K----------G----SV-----------------------------------------ANMSLG---------GGR---A---------------------K--------------------------TLDD-----AVDA-A--------VEA----GL-----H--------------------------------------------------------------------------------------F---------------AVAAG-ND--------NK---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-S----KF---------------------A---VT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------GD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---K--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----GNS--------TT-NT----------------ISG------TSMASPHVC----G---------------------------L------------------LA-Y----LL----S-------IY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 460
 461 TELGAPW-------GLARISHRDRLS----------LSTFQKYLY-------Y-S-GGGD--------------------------G-V--VA--------------Y--------------------VID---------------------------T--------------GINT-D------H-------------V---------E--------------------------------F---------------------E----------------G-----------------------------------------------------RAV----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPKNDV------------DK-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----SRK----------------------------------------------------Y-------------------GV--AKD-V--KLVAV---KV---LGSN----------G-SG--T------------MSD-------------------------------------V--------IAG--------------V-----------LW---AAEQATEDAERAAQEVATTGKTK-----H------K----------G----SV-----------------------------------------ANMSLG---------GGR---A---------------------K--------------------------TLDD-----AVDA-A--------VEA----GL-----H--------------------------------------------------------------------------------------F---------------AVAAG-ND--------NK---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-S----KF---------------------A---VT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------GD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------H-G---K--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----GNS--------TT-NT----------------ISG------TSMASPHVC----G---------------------------L------------------LA-Y----FV----S-------IYGTESFPHIKSDFNESLAATRPSIVSMA---YAQAYAMLPSLAQTVLPKPELLPVP----PKNDTLT---PDM--------------L---------------------KKAL-------VGL-------------------------AT------------------------------------------------------------------------K------DMLSDLP--------------------- 461
 462 IQKSATW-------GLARISHRPRLT----------FGTFTKYLY-------D-D-VAGE--------------------------G-V--DV--------------Y--------------------VVD---------------------------T--------------GINI-D------H-------------V---------E--------------------------------F---------------------E----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------WG----------------KTVPQNDI------------DE-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIA----SRK----------------------------------------------------Y-------------------GV--AKK-A--NVIAI---KV---LGTN----------G-SG--T------------MSD-------------------------------------V--------IDG--------------V-----------LW---AAQQAAKKAAAADAEFAATGRTS-----H------K----------G----SV-----------------------------------------ANMSLG---------GGK---S---------------------Q--------------------------ALDT-----AVNK-A--------VLS----GL-----H--------------------------------------------------------------------------------------F---------------AVAAG-ND--------NR---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----EN---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------GD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------W-G---A--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TYK--------------------------------------------------------------------------------------------------------G-----SRT--------AT-ST----------------LSG------TSMASPHTA----G---------------------------L------------------LA-Y----LL----S-------IYPHASFDPTFDAEENLISLTNDKLLSKTTSIYALAHATLPQWIANFLPSPSLVEASIAPVPKRPTLT---PLQ--------------L---------------------KKAV-------IAL-------------------------TT------------------------------------------------------------------------K------NVLSGLP--------------------- 462
 463 VEKNAPW-------GLARISHRDRLT----------FGTFNKYLY-------A-S-EGGE--------------------------G-V--DV--------------Y--------------------TID---------------------------T--------------GINI-E------H-------------E---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RAF----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPNNDA------------DE-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------SGTIA----GKK----------------------------------------------------Y-------------------GV--SKK-A--NIYAV---KV---LRSS----------G-SG--T------------MAD-------------------------------------V--------VQG--------------V-----------EW---AV--------ESHLKKAKKGGNG-----F------K----------G----SV-----------------------------------------ANMSLG---------GGK---S---------------------K--------------------------TLED-----AVNA-G--------VEA----GV-----H--------------------------------------------------------------------------------------F---------------AVAAG-ND--------NA---------D----A---CSYS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-A----EK---------------------A---VT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------AD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---K--------------------CT------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----SKS--------AV-NT----------------ISG------TSMASPHIA----G---------------------------L------------------LA-Y----FV----S-------LQPSKD------------------------------------------------------SAFAVDFT---PEK--------------L---------------------KKDI-------ISI-------------------------AT------------------------------------------------------------------------E------GVLTDIP--ADTPNLLAWNGGGSTNYSD 463
 464 TQNGAPW-------GLARVSHREKLN----------SGSFNKYLY-------D-D-NSGE--------------------------G-V--TS--------------Y--------------------VID---------------------------T--------------GINI-D------H-------------V---------D--------------------------------F---------------------E----------------D-----------------------------------------------------RAL----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPNNDA------------DY-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIA----SKT----------------------------------------------------Y-------------------GV--AKK-A--NVVAV---KV---LRSN----------G-TG--S------------MSD-------------------------------------V--------LRG--------------V-----------EY---AV--------KAHRKAAEKADKG-----F------K----------G----ST-----------------------------------------ANMSLG---------GGR---S---------------------Q--------------------------ALDL-----AVDA-A--------VDA----GI-----H--------------------------------------------------------------------------------------F---------------AVAAG-NE--------NQ---------D----A---CNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-S----QK---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------AD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------W-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------MN--------------------------------I------------------------------------------------------------------LS-TYI--------------------------------------------------------------------------------------------------------G-----SDT--------AV-AT----------------LSG------TSMASPHVA----G---------------------------L------------------LT-Y----FL----S-------LQPDGD--------------------------------------------------SEF--RNKQTIS---PEV--------------L---------------------KKKV-------IDF-------------------------GT------------------------------------------------------------------------K------DALSSLP--ARTANVLIYNGGGADLSDF 464
 465 TQNSAPW-------GLARISHRERLN----------LGSFNKYLY-------D-D-DAGR--------------------------G-V--TS--------------Y--------------------VID---------------------------T--------------GVNI-N------H-------------K---------D--------------------------------F---------------------E----------------K-----------------------------------------------------RAI----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPLNDE------------DL-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIA----SKH----------------------------------------------------Y-------------------GV--AKN-A--NVVAV---KV---LRSN----------G-SG--T------------MSD-------------------------------------V--------VKG--------------V-----------EY---AA--------KAHQKEAQEKKKG-----F------K----------G----ST-----------------------------------------ANMSLG---------GGK---S---------------------P--------------------------ALDL-----AVNA-A--------VEV----GI-----H--------------------------------------------------------------------------------------F---------------AVAAG-NE--------NQ---------D----A---CNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----DK---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------W-G---K--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TYI--------------------------------------------------------------------------------------------------------G-----SDD--------AT-AT----------------LSG------TSMASPHVA----G---------------------------L------------------LT-Y----FL----S-------LQPGSD--------------------------------------------------SEFFELGQDSLT---PQQ--------------L---------------------KKKL-------IHY-------------------------ST------------------------------------------------------------------------K------DILFDIP--EDTPNVLIYNGGGQDLSAF 465
 466 IEKGAPW-------GLARVSHRQPLS----------LSSFDQYLY-------D-S-EAGA--------------------------G-V--TA--------------Y--------------------VID---------------------------T--------------GVNV-K------H-------------E---------E--------------------------------F---------------------S----------------G-----------------------------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPQGDS------------DI-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----SND----------------------------------------------------Y-------------------GV--AKK-A--EIVAV---KV---LRSN----------G-SG--T------------MSD-------------------------------------V--------VKG--------------V-----------EY---AA--------KSHQEAVKSSKKG-----F------K----------G----ST-----------------------------------------ANMSLG---------GGK---S---------------------P--------------------------ALDL-----AVNA-A--------VKA----GL-----H--------------------------------------------------------------------------------------F---------------AVAAG-NE--------NQ---------D----A---CNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----EL---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------SD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---K--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TYI--------------------------------------------------------------------------------------------------------G-----SDT--------AT-AY----------------LSG------TSMASPHIC----G---------------------------L------------------LS-Y----FV----S-------LQPGAD--------------------------------------------------SEFF-VAADGIS---PSQ--------------L---------------------KKNL-------IAY-------------------------GT------------------------------------------------------------------------S------DVLSDIP--EDTPNILAFNGAGHNLTKF 466
 467 -QRNAPW-------GLARVSHKDSLT----------FKNYENYEH-------D-P-NGGE--------------------------G-V--KV--------------Y--------------------VID---------------------------T--------------GINV-D------H-------------V---------D--------------------------------F---------------------N----------------G-----------------------------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------WG----------------HTVPSGDV------------DA-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIA----GGR----------------------------------------------------Y-------------------GI--AKK-A--EPVAV---KV---LRSN----------G-SG--T------------MSD-------------------------------------V--------VKG--------------V-----------DW---ATAEH-----IKAKALARKDGKK-----Y------K----------G----AV-----------------------------------------ANMSLG---------GGR---S---------------------P--------------------------TLDR-----FVNG-A--------VQA----GI-----V--------------------------------------------------------------------------------------F---------------SVAAG-ND--------ND---------D----A---CDYS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-A----EL---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------KD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---K--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------YN--------------------------------I------------------------------------------------------------------LS-IWK--------------------------------------------------------------------------------------------------------G-----SRY--------AT-NT----------------ISG------TSMAAPHVA----G---------------------------L------------------AA-Y----YL----S-------LEE-DA-------------------------------------------------------------T---AEK--------------I---------------------KEKI-------LST-------------------------AT----------------------------------------------------------------------------------------------------------- 467
 468 -QRNAPW-------GLARVSHKKHLT----------PKTFDKYIH-------N-P-LGGQ--------------------------G-V--RV--------------Y--------------------VID---------------------------T--------------GINI-D------H-------------V---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RAI----------------------------------------------------------------------------------------------------------------------------------WG----------------HTVPKNDF------------DE-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIA----GKT----------------------------------------------------Y-------------------GI--AKK-A--KPVAV---KV---LGSD----------G-SG--T------------MSD-------------------------------------V--------IKG--------------V-----------DW---VTAEH-----IKAKALAQKNRKK-----Y------K----------G----AV-----------------------------------------ANMSLG---------GGR---S---------------------L--------------------------SLDR-----FVNG-A--------VRA----GI-----V--------------------------------------------------------------------------------------F---------------SVAAG-ND--------NE---------D----A---CNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-A----EL---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------ED-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---K--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----SRY--------AT-NI----------------ISG------TSMAAPHVA----G---------------------------L------------------AA-Y----FL----S-------LTEGPA-------------------------------------------------------------T---AKK--------------I---------------------KDMI-------LKT-------------------------AT----------------------------------------------------------------------------------------------------------- 468
 469 -QRSAPW-------GLARISTRDSLT----------LKNYNKYNY-------DEK-TAGE--------------------------G-I--KV--------------Y--------------------VID---------------------------T--------------GINV-D------H-------------V---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------WG----------------KTIPTDDT------------DQ-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-C-----------------------AGTIA----GKK----------------------------------------------------Y-------------------GV--AKK-A--EPVAV---KV---LKSN----------G-SG--S------------MSD-------------------------------------V--------VAG--------------V-----------DW---ATSDF-----LKRKKQAQEAGKP-----F------K----------G----AA-----------------------------------------ANMSLG---------GGK---S---------------------A--------------------------ALDR-----IVNG-A--------VDA----GL-----V--------------------------------------------------------------------------------------F---------------AVAAG-ND--------NK---------D----A---CDYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----EK---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------FD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---K--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------LD--------------------------------I------------------------------------------------------------------QS-IWI--------------------------------------------------------------------------------------------------------G-----SKT--------AT-NT----------------ISG------TSMASPHVA----G---------------------------L------------------AA-Y----FL----S-------QAEPGA-------------------------------------------------------------T---PKS--------------I---------------------KEKI-------INV-------------------------ST----------------------------------------------------------------------------------------------------------- 469
 470 TQSGAPW-------GLARISH-KSVK----------YDDIGKYVY-------D-S-SAGD--------------------------N-I--TA--------------Y--------------------VVD---------------------------T--------------GVSI-H------H-------------V---------E--------------------------------F---------------------E----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------WG----------------ATIPSGDV------------DE-----------------------------------------------------------------------------------------D---N---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----SRA----------------------------------------------------Y-------------------GV--AKK-A--EIVAV---KV---LRSS----------G-SG--T------------MAD-------------------------------------V--------IAG--------------V-----------EW---TV--------RHHKSSGKK---------------------------T----SV-----------------------------------------GNMSLG---------GGN---S---------------------F--------------------------VLDM-----AVDS-A--------VTN----GV-----I--------------------------------------------------------------------------------------Y---------------AVAAG-NE--------YD---------D----A---CYSS---------------------------------------------------------------------------------------------------------------------------------------P-A--A-S----KK---------------------A---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------ND-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-AYF-----S--N--------Y-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----SNT--------ST-NT----------------ISG------TSMATPHVA----G---------------------------L------------------SA-Y----YL----G-------LHP--A------------------------------------------------------------AS---ASE--------------V---------------------KDAI-------IKM-------------------------GI------------------------------------------------------------------------H------DVLLSIPVGSSTINLLAFNGAQE----- 470
 471 LQEEAPW-------GLHRVSHREKPK----------YGQDLEYLY-------E-D-AAGK--------------------------G-V--TS--------------Y--------------------VLD---------------------------T--------------GIDT-E------H-------------E---------D--------------------------------F---------------------E----------------G-----------------------------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------WG----------------AVIPANDE------------AS-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIIG----SKH----------------------------------------------------F-------------------GV--AKN-T--KIVAV---KV---LRSN----------G-EG--T------------VSD-------------------------------------V--------IKG--------------I-----------EY---VT--------KEHIESSKKKNKE-----F------K----------G----ST-----------------------------------------ANLSLG---------SSK---S---------------------L--------------------------AMEM-----AVNA-A--------VDS----GV-----H--------------------------------------------------------------------------------------F---------------AIAAG-NE--------DE---------D----A---CLSS---------------------------------------------------------------------------------------------------------------------------------------P-A--G-A----EK---------------------S---IT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AFF-----S--N--------W-G---T--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------IN--------------------------------I------------------------------------------------------------------MS-TYI--------------------------------------------------------------------------------------------------------G-----SRN--------AT-LS----------------LSG------TSMASPHVA----G---------------------------I------------------LS-Y----FL----S-------LQPAPD-----------------------------------------------------SEFFNDAPS---PQE--------------L---------------------KEKV-------LKF-------------------------ST------------------------------------------------------------------------Q------GVLGDIG--DDTPNKLIYNGGGKKLDGF 471
 472 EQTFAPW-------GLARVSHRKKLG----------FFTMTRYQY-------N-E-TAGE--------------------------G-V--TA--------------Y--------------------VID---------------------------T--------------GINI-E------H-------------Q---------D--------------------------------F---------------------Q----------------G-----------------------------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------WG----------------ATIPTGEG------------EV-----------------------------------------------------------------------------------------D---D---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIA----GKT----------------------------------------------------F-------------------GV--SKN-A--KLVAV---KV---MRAD----------G-TG--T------------VSD-------------------------------------I--------IKG--------------I-----------EF---AF--------KQSKKDKES----------------I----------A----SV-----------------------------------------VNMSIG---------GDA---S---------------------T--------------------------ALDL-----AVNA-A--------IAG----GL-----F--------------------------------------------------------------------------------------F---------------AVAAG-ND--------AE---------D----A---CGTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-V----SN---------------------A---MT---VG--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------W-------------------------------------------------------------------------------------ND-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ASF-----S--N--------I-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SL--------------------------------I------------------------------------------------------------------LS-DWI--------------------------------------------------------------------------------------------------------G-----SNR--------AS-MI----------------LSG------TSMASPHVA----G---------------------------L------------------AA-Y----FI----S-------LDPSLA------------------------------------------------------------NH---PVE--------------L---------------------KKYM-------LKF-------------------------AL------------------------------------------------------------------------K------DLLNGIP--EDTPNVLAFNNYE------ 472
 473 IQKDATW-------GISRVSHRENID----------DG---KYLF-------D-N-DGGK--------------------------G-V--TA--------------Y--------------------VID---------------------------T--------------GIKV-G------H-------------P---------D--------------------------------F---------------------E----------------D-----------------------------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------WG----------------ASIAFPNI------------KQ-----------------------------------------------------------------------------------------D---Y---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----SKT----------------------------------------------------Y-------------------GI--AKN-V--NLVAV---GV---MNML----------G-AG--S------------TSD-------------------------------------I--------IKG--------------L-----------EF---VV--------KSHQDDVRAKKKG-----F------K----------G----ST-----------------------------------------VNMSIG---------GGI---S---------------------D--------------------------ALDL-----AVNA-G--------TKA----GL-----H--------------------------------------------------------------------------------------I---------------SVAAG-ND--------NA---------D----A---CQYS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----TG---------------------P---IT---IG--A------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------RD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-ASF-----S--N--------W-G---S--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------ES-TFI--------------------------------------------------------------------------------------------------------W-----SD----------T-TV----------------MSG------TSMASPHIA----G---------------------------L------------------LS-Y----YL----S-------LQPDVT-----------------------------------------------------SEFYTQAIE---PAD--------------L---------------------KNKL-------IKY-------------------------GT------------------------------------------------------------------------K------GVLTGLD--SVSPNILAFNGAGGNLTDF 473
 474 VMTIFDTQPKAPSWGLTRISFRDHP-DASQKV-YSYP-SSAGT-------------------------------------------G-V--NA--------------Y--------------------IID---------------------------T--------------GVFI-K------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AHLGKS----------------------------FT---KDGNN----DGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----SKS-----------------------------------------------------------------------YGV--AKN-V--TLIAV---KV---LDNQ----------G-SG--T------------TSD-------------------------------------V--------IAG--------------I-----------DW---AS----------------KDAAAKNGKDK------P----------LK---SV-----------------------------------------ANMSLG-GGASA-------ALD---------------------K-----------------------------------AVKA---------ATKN----GL-----V--------------------------------------------------------------------------------------F---------------AVAAG-NS-GR-----DA------------------CSLS---------------------------------------------------------------------------------------------------------------------------------------P-ARVPEA-------------------------------IT---VA--A------------------------------S----------------------------DK--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NL-ASF-----S--E--------R-GKC-V----------------------------------------------------------------------D-----V------I-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------TWNNGKIN---T----------------ISG------TSMATPHVV----G---------------------------V------------------VALALA---E-------------GSFTQ-----------------------------------------------------------------VKA--------------V---------------------HDYI-------KLV-------------------------------------------------------------------------------------------------ASKDRIS-----GDL---RGAPNSLLYNNVIDGGFPD 474
 475 KVEKACEEQPEVTWGLARISKEDA---YTPNDPYRYESDGIGE-------------------------------------------D-V--YI--------------Y--------------------IID---------------------------T--------------GTRV-G------H-------------V---------D--------------------------------Y-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------AELGVDCY-------------------------TSLDCIPATGF----DAN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------GSTAA----GTT-----------------------------------------------------------------------YGV--AKK-A--TIYPV---KV---LSDG----------G-SG--S------------YEQ-------------------------------------V--------VAG--------------V-----------VY---TT----------------NE-----KRSN------P----------SRK--VV-----------------------------------------ANMSLG-GPASQ-------LLD---------------------D-----------------------------------AVNE---------AVDE----GV-----H--------------------------------------------------------------------------------------M---------------VVAAG-NE-FQ-----DA------------------CLRS---------------------------------------------------------------------------------------------------------------------------------------P-ARANGV-------------------------------TT---VG--A------------------------------T----------------------------DI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QA-AYF-----T--N--------F-GEC-V----------------------------------------------------------------------A-----I------F-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IA----------------------------------------------------------------------------------------------------------------------ASGASDTAT-AT----------------YSG------TSMASPHVA----G---------------------------V------------------VASILS----------------RCDDVP-----------------------------------------------------------------PAD--------------M---------------------EVFI-------KSI-------------------------------------------------------------------------------------------------AS----------------------------------- 475
 476 QSGAP-W-------GLGRIS--------HRSKGST-TYR-----Y-------DD--SAGQ--------------------------G-T--CV--------------Y--------------------IID---------------------------T--------------GIEA-S------H-------------P---------E--------------------------------F--------------------------------------E----------------------G------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------FL------KSF-I-----SGQN-----------------T-----------------------------------------------------------------------------------------D---G---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIG----SKT----------------------------------------------------Y-------------------GV--AKK-A--KLYGV---KV---LDNQ----------G-SG--S------------YSG-------------------------------------I--------ISG--------------M-----------DY---VA----------QDSK-TR--GC-----P------N----------G----AI-----------------------------------------ASMSLG---------GGY---S---------------------A--------------------------SVNQ-----GAAA-L--------VNS----GV-----F--------------------------------------------------------------------------------------L---------------AVAAG-ND--------NR---------D----A---QNTS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-E----PS---------------------A---CT---VG--A------------------------------S-----------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------------------------------------------------------------------------------------ND-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---R--------------------VV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SN--------------------------------V------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------V-----G----------RT-NS----------------ISG------TSMATPHIA----G---------------------------L------------------AA-Y----LS----A-------LQ-GKT-------------------------------------------------------------T---PAA--------------L---------------------CKKI-------QDT-------------------------AT------------------------------------------------------------------------K------NVLTGVPS--GTVNYLAYNGA------- 476
 477 QTNAP-W-------GLARIS--------STSPGTS-TYY-----Y-------DE--SAGQ--------------------------G-S--CV--------------Y--------------------VID---------------------------T--------------GIEA-S------H-------------P---------E--------------------------------F--------------------------------------E----------------------G------------------------------RAQ----------------------------------------------------------------------------------------------------------------------------------MV------KTY-Y-----YSSR-----------------------------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTVG----SRT----------------------------------------------------Y-------------------GV--AKK-T--QLFGV---KV---LDDN----------G-SG--Q------------YST-------------------------------------I--------IAG--------------M-----------DF---VA----------SDKN-NR--NC-----P------K----------G----VV-----------------------------------------ASLSLG---------GGY---S---------------------S--------------------------SVNS-----AAAR-L--------QSS----GV-----M--------------------------------------------------------------------------------------V---------------AVAAG-NN--------NA---------D----A---RNYS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-E----PS---------------------V---CT---VG--A------------------------------S-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------YD-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-SSF-----S--N--------Y-G---S--------------------VL------------------------------------------------D-----I------F-----------------G-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------LS-TWI--------------------------------------------------------------------------------------------------------G-----G----------ST-RS----------------ISG------TSMATPHVA----G---------------------------L------------------AA-Y----LM----T-------L--GKT-------------------------------------------------------------T---AAS--------------A---------------------CRYI-------ADT-------------------------AN------------------------------------------------------------------------K------GDLSNIPF--GTVNLLAYNNYQA----- 477
 478 QEDAP-W-------GLARIS--------SQEPGGT-TYT-----Y-------DD--SAGT--------------------------G-T--CA--------------Y--------------------IID---------------------------T--------------GIYT-N------H-------------T---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------FL------KNFAG-----DGQD-----------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----GTT----------------------------------------------------Y-------------------GV--AKK-T--SLFAV---KV---LDAN----------G-QG--S------------NSG-------------------------------------V--------IAG--------------M-----------DF---VT----------KDAS-SQ--NC-----P------K----------G----VV-----------------------------------------VNMSLG---------GPS---S---------------------S--------------------------AVNR-----AAAE-I--------TSA----GL-----F--------------------------------------------------------------------------------------L---------------AVAAG-NE--------AT---------D----A---SSSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-E----ES---------------------A---CT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------TD-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-AEY-----S--N--------F-G---S--------------------VV------------------------------------------------D-----L------L-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------KS-TWN--------------------------------------------------------------------------------------------------------D-------G--------RT-KI----------------ISG------TSMASPHVA----G---------------------------L------------------GA-Y----FL----G-------LG-QKV-------------------------------------------------------------Q-----G--------------L---------------------CDYM-------VEK-------------------------GL------------------------------------------------------------------------K------DVIQSVPS--DTANVLINNGEGSA---- 478
 479 QSNVPSW-------GLARIS--------SKRTGTT-SYT-----Y-------DS--TAGE--------------------------G-V--VF--------------Y--------------------GVD---------------------------T--------------GIDI-S------H-------------S---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAK----------------------------------------------------------------------------------------------------------------------------------WG------TNV-V-----DNDN-----------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSK----------------------------------------------------Y-------------------GV--AKK-A--TLVAV---KV---LGAD----------G-SG--T------------NSG-------------------------------------V--------ISG--------------M-----------DW---AV----------KDAK-SR--GA-----N------G----------K----YV-----------------------------------------MNTSLG---------GEF---S---------------------K--------------------------AVND-----AAAN-V--------VKS----GI-----F--------------------------------------------------------------------------------------L---------------SVAAG-NE--------AE---------N----A---SNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----AE---------------------A---CT---IA--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-ASF-----T--N--------F-G---S--------------------VV------------------------------------------------D-----L------Y-----------------A-----P-------------G-----------------QS--------------------------------I------------------------------------------------------------------TA-AYP--------------------------------------------------------------------------------------------------------G-------G--------GS-KT----------------LSG------TSMAAPHVA----G---------------------------V------------------AA-Y----LM----A-------LE-G-V-------------------------------------------------------------S---AGN--------------A---------------------CARI-------VQL-------------------------AT-------------------------------------------------------------------------------SSISRAPS--GTTSKLLYNGINV----- 479
 480 QLASPSW-------GLSRIS--------SKKSGAT-DYV-----Y-------DS--TAGE--------------------------G-I--VI--------------Y--------------------GVD---------------------------T--------------GIDI-G------H-------------A---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAE----------------------------------------------------------------------------------------------------------------------------------TG------TNT-A-----DNDD-----------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSK----------------------------------------------------F-------------------GV--AKK-A--SVVAV---KV---LGAD----------G-SG--T------------NSQ-------------------------------------V--------IAG--------------M-----------DW---AV----------KDSK-SR--GA-----T------G----------K----SV-----------------------------------------MNMSLG---------GAY---S---------------------R--------------------------AMND-----AAAN-V--------VRS----GV-----F--------------------------------------------------------------------------------------L---------------SVAAG-NE--------AQ---------D----A---SNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PN---------------------V---CT---IA--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------SD-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-ASF-----T--N--------F-G---S--------------------VV------------------------------------------------D-----L------Y-----------------A-----P-------------G-----------------KD--------------------------------I------------------------------------------------------------------TA-AYP--------------------------------------------------------------------------------------------------------G-------G--------GS-KT----------------LSG------TSMATPHVA----G---------------------------L------------------AS-Y----LM----A-------LE-K-T-------------------------------------------------------------T---ASA--------------A---------------------CNRI-------VQD-------------------------AT-------------------------------------------------------------------------------TKIAGAPK--GTTNLLAYNGI------- 480
 481 QPNAPTW-------GLGRVS--------HKAPGNK-DFV-----Y-------DS--SAGQ--------------------------G-V--TI--------------Y--------------------GVD---------------------------T--------------GIDI-N------H-------------P---------E--------------------------------F--------------------------------------R----------------------G------------------------------RIR----------------------------------------------------------------------------------------------------------------------------------WG------TNT-V-----DNDN-----------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------AGTFA----GTT----------------------------------------------------Y-------------------GV--AKK-A--NIVAV---KV---LSAG----------G-SG--S------------TAG-------------------------------------V--------IKG--------------I-----------DW---CV----------TDAK-AK--GA-----L------G----------K----AA-----------------------------------------LNLSLG---------GAF---S---------------------Q--------------------------ANND-----AVTR-A--------QNA----GI-----F--------------------------------------------------------------------------------------V---------------AVAAG-ND--------NK---------D----A---KNSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PA---------------------V---CT---AA--S------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------DD-------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-SSF-----S--N--------W-G---T--------------------IV------------------------------------------------D-----I------Y-----------------A-----P-------------G-----------------SN--------------------------------I------------------------------------------------------------------LS-AAP--------------------------------------------------------------------------------------------------------G-------G--------GT-RT----------------LSG------TSMASPHVC----G---------------------------V------------------GA-A----ML----A--------Q-G-V-------------------------------------------------------------S---VAQ--------------A---------------------CDRI-------KQI-------------------------AN-------------------------------------------------------------------------------AVIKNPGT--GTTNKLLYNGSGR----- 481
 482 QSDAP-W-------GLQRVSQAARLSNTDVAALDY-QYT-----Y-------DS--SAGS--------------------------G-V--DI--------------Y--------------------IAD---------------------------T--------------GILV-S------H-------------S---------Q--------------------------------F--------------------------------------G----------------------G------------------------------RAR----------------------------------------------------------------------------------------------------------------------------------WG------GTF-G-----VTGT-----------------T-----------------------------------------------------------------------------------------D---G---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAA----GAQ----------------------------------------------------F-------------------GV--AKN-A--SLIAV---KV---LTDG----------G-SG--S------------IAG-------------------------------------I--------VSG--------------L-----------DW---IR----------TQVA-AS--GR-----------------------P----SV-----------------------------------------VSMSLG---------GSA---S---------------------T--------------------------ALDN-----AVAS-L--------TAA----GI-----H--------------------------------------------------------------------------------------V---------------TVAAG-ND--------NR---------D----A---ANTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-T----PS---------------------A---IT---VG--A------------------------------T-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------QD-------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-ASF-----S--N--------F-G---A--------------------AV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------QN--------------------------------V------------------------------------------------------------------IS-AWI--------------------------------------------------------------------------------------------------------G----ASNS--------AT-NS----------------ISG------TSMATPHVA----G---------------------------L------------------VA-Y----LI----S-------KD-GNI-------------------------------------------------------------S---PAA--------------M---------------------EAKI-------KDL-------------------------SV------------------------------------------------------------------------K------GAVTGLP--------------------- 482
 483 QTNAP-W-------GLQRITQPGRLASQSTSSANY-NFT-----Y-------DA--SAGA--------------------------G-V--DI--------------Y--------------------VVD---------------------------T--------------GVQT-S------H-------------S---------D--------------------------------F--------------------------------------G----------------------G------------------------------RAR----------------------------------------------------------------------------------------------------------------------------------WG------VSY-------VSES-----------------T-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTAA----GTR----------------------------------------------------F-------------------GV--AKR-A--NIIAV---QV---LNRS----------G-SG--A------------TSG-------------------------------------I--------VSG--------------L-----------QW---VL----------NQAR-AS--GR-----------------------P----SV-----------------------------------------VSMSLG---------GGA---S---------------------T--------------------------ATDN-----AVAQ-L--------TAA----GI-----H--------------------------------------------------------------------------------------V---------------VVAAG-NS--------NV---------N----A---ANTS---------------------------------------------------------------------------------------------------------------------------------------P-A--R-A----PS---------------------A---IT---VA--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------AD-------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-ASY-----S--N--------Y-G---A--------------------VI------------------------------------------------D-----V------W-----------------A-----P-------------G-----------------SN--------------------------------I------------------------------------------------------------------LS-AWI--------------------------------------------------------------------------------------------------------G-----SNT--------AT-NN----------------ISG------TSMATPHVA----G---------------------------V------------------VA-Y----LI----G-------RD-GNI-------------------------------------------------------------S---PAA--------------M---------------------ATKI-------KNL-------------------------AV------------------------------------------------------------------------K------NVLSGVP--------------------- 483
 484 QTDST-W-------GLDRIS--------HEDYSAPYTYE-----Y-------DET-AAGA--------------------------G-T--TV--------------Y--------------------VID---------------------------T--------------GIRI-S------H-------------D---------E--------------------------------F--------------------------------------QTVNG-----------------SS------------------------------RAT----------------------------------------------------------------------------------------------------------------------------------WG------FNS-V-----DKTD-----------------S-----------------------------------------------------------------------------------------D---G---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGTIA----GKT----------------------------------------------------Y-------------------GV--SKK-A--KVVAV---KV---LSAG----------G-SG--S------------TAG-------------------------------------V--------VSG--------------M-----------NW---VA----------ENAT------------P------N----------F----SV-----------------------------------------ASMSLG---------GSK---S---------------------A--------------------------ALNT-----AVDA-I--------FNA----GI-----T--------------------------------------------------------------------------------------I---------------VVAAG-NE--------NQ---------D----A---KNVS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PN---------------------A---IT---VG--A------------------------------I-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------SN-------K-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-ASF-----S--N--------W-G---T--------------------LI------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------LS-SWA--------------------------------------------------------------------------------------------------------T-----SDK--------ET-KT----------------ISG------TSMACPHVA----G---------------------------L------------------AAYY----IS----A-------SE-GGA-------------------------------------------------------------D---PAT--------------I---------------------TDKI-------TSS-------------------------AV------------------------------------------------------------------------S------GQVTGNIR--GSPNKIAYNGYA------ 484
 485 SQSGAPW-------GLGAISHKGEAS---------------TTYV-------YDT-SAGE--------------------------G-T--YA--------------Y--------------------VVD---------------------------T--------------GINA-D------H-------------E---------E--------------------------------F---------------------G----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------LA------YNA-----------VGGQ------------HV-----------------------------------------------------------------------------------------D---S---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTIG----GET----------------------------------------------------Y-------------------GV--SKK-A--NLLSV---KV---FQGE------------SS--S------------TSI-------------------------------------I--------LDG--------------F-----------NW---AA-------------NDIVSKGR-----T------G----------K----SA-----------------------------------------INMSLG---------GGY---S---------------------Y--------------------------AFNQ-----AVED-A--------YDE----GV-----L--------------------------------------------------------------------------------------S---------------VVAAG-ND--------NI---------D----A---SDSS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PN---------------------A---LT---VA--A------------------------------S-----------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------SN-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-ASF-----S--N--------Y-G---S--------------------VV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------LS-AWI--------------------------------------------------------------------------------------------------------G-----STT--------AT-NT----------------ISG------TSMATPHVV----G---------------------------L------------------SL-Y----LI----A-------LEGLSS-----------------------------------------------------------------ASA--------------V---------------------VSRI-------KEL-------------------------AT------------------------------------------------------------------------Q------G-VLSNVQ--GSPNLLAYNGADE----- 485
 486 TQSDAPW-------GLGSISHKGQPS---------------TDYI-------YDT-NGGE--------------------------G-T--YA--------------Y--------------------VVD---------------------------I--------------GINV-D------H-------------E---------E--------------------------------F---------------------E----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------LA------YHA-----------AGGQ------------HV-----------------------------------------------------------------------------------------D---G---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTIG----GKT----------------------------------------------------Y-------------------GV--AKK-A--NLLSV---KV---FVGE------------SS--S------------TSI-------------------------------------I--------LDG--------------F-----------NW---AA-------------NDIVSKKR-----T------G----------K----AA-----------------------------------------INMSLG---------GGY---S---------------------K--------------------------AFND-----AVEN-A--------FNE----GV-----L--------------------------------------------------------------------------------------S---------------IVAAG-NE--------NT---------D----A---SRTS---------------------------------------------------------------------------------------------------------------------------------------P-A--S-A----PD---------------------A---FT---VA--A------------------------------I-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------NN-------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-AYF-----S--N--------Y-G---S--------------------VV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------QN--------------------------------I------------------------------------------------------------------LS-AWI--------------------------------------------------------------------------------------------------------G-----SNT--------AT-NT----------------ISG------TSMATPHIV----G---------------------------L------------------SI-Y----LM----S-------LEVLSS-----------------------------------------------------------------PKA--------------V---------------------SDRI-------KEL-------------------------AT------------------------------------------------------------------------R------G-VVSNVA--GSPNLLAYNGNA------ 486
 487 TQSGAPW-------GLGTVSHRTSGS---------------TSYI-------YDS-SAGA--------------------------G-T--FA--------------Y--------------------VVD---------------------------S--------------GINT-S------H-------------Q---------Q--------------------------------F---------------------G----------------G-----------------------------------------------------RAS----------------------------------------------------------------------------------------------------------------------------------LG------YNA-----------AGGQ------------HV-----------------------------------------------------------------------------------------D---T---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGTIG----GST----------------------------------------------------Y-------------------GV--AKQ-A--SLISV---KV---FAGE------------SA--S------------TSV-------------------------------------I--------LDG--------------Y-----------NW---AV-------------NDIVSKSR-----A------S----------K----SA-----------------------------------------INMSLG---------GPA---S---------------------S--------------------------TWTT-----AINA-A--------FNQ----GV-----L--------------------------------------------------------------------------------------T---------------IVAAG-NG--------DSLG----NPQP----V---SGTS---------------------------------------------------------------------------------------------------------------------------------------P-A--N-V----PN---------------------A---IT---VA--A------------------------------L-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------NW-------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-ASF-----T--N--------Y-G---A--------------------GV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-SWI--------------------------------------------------------------------------------------------------------G-----SNT--------AT-NT----------------ISG------TSMATPHVV----G---------------------------L------------------AL-Y----LQ----S-------LEGLTS-----------------------------------------------------------------PTA--------------V---------------------TNRI-------KAL-------------------------AT------------------------------------------------------------------------S------GRVTGSLN--GSPNVIIFNGNSS----- 487
 488 -----------------------------------------GE-------------------------------------------G-V--NV--------------Y--------------------VLD---------------------------S--------------GIYK-S------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-GR-------------------------------------AHFGIDTT-------------------------KEGPG----------DLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLVG----SRT-----------------------------------------------------------------------FGI--AKK-A--NIYEI---KV---MTVD----------G-RG--S------------TSN-------------------------------------I--------IAG--------------V-----------EF---AV----------------KHCQQ------------S----------GKR--CV-----------------------------------------ANMSLGGLSFGHS------ALD---------------------S-----------------------------------AVEA---------AIEE----GL-----V--------------------------------------------------------------------------------------F---------------VVAAG-N-SKE-----RA------------------CWYS---------------------------------------------------------------------------------------------------------------------------------------P-AKVKTA-------------------------------IT---VG--A------------------------------F---------------------------DDR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------II-ASF-----S--N--------Y-GKC-V----------------------------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------VA--------------------------------V------------------------------------------------------------------AS----------------------------------------------------------------------------------------------------------------------LSNSPSNTM-RV----------------LNG------TSMSAPITA----G---------------------------V------------------VAVLLD----------------Q--GIE-----------------------------------------------------------------PHE--------------V---------------------KDHL-------LSI-------------------------------------------------------------------------------------------------ST----------------------------------- 488
 489 -------ISRHYQLPFDVGDKDR----YKSWFNYYYEHDYQGQ-------------------------------------------D-V--NA--------------Y--------------------IMD---------------------------T--------------GIFA-D------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-DR-------------------------------------VIQGIDLT-------------------------KEGFG----------DQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLVG----SKT-----------------------------------------------------------------------YGA--AKR-V--NLVEV---KV---LGKD----------G-SG--E------------ASN-------------------------------------V--------LSG--------------L-----------EF---IV----------------EHCTKVS--RP------Q----------GKK--CV-----------------------------------------ANLSLG--SFRSP------IIN---------------------M-----------------------------------AVEG---------AIEE----GI-----V--------------------------------------------------------------------------------------F---------------VAAAG-N-FNL-----DA------------------YWAS---------------------------------------------------------------------------------------------------------------------------------------P-ASAENV-------------------------------IT---VG--A------------------------------F---------------------------DDH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TI-AKF-----S--N--------W-GPC-V----------------------------------------------------------------------N-----I------F-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------ES----------------------------------------------------------------------------------------------------------------------LSHLNYNDT-LI----------------LSG------TSMSTPIVT----G---------------------------V------------------AAILLS----------------K--GIE-----------------------------------------------------------------PEM--------------I---------------------AQEI-------EYL-------------------------------------------------------------------------------------------------STRNVFHRRTLFFK----PSTPNQILYNGV------D 489
 490 -------------------------------YPYMYETEYSGQ-------------------------------------------G-V--NA--------------Y--------------------VID---------------------------S--------------GIEV-D------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------ASAGYDFT-------------------------EEGSG----------DNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLIG----SVT-----------------------------------------------------------------------YGV--AKN-V--RIVEV---KA---LNSK----------G-AG--S------------LST-------------------------------------I--------LAA--------------I-----------DF---AV----------------NHRIE------------S----------GRK--GV-----------------------------------------ANLSLG--AYKNH------ILN---------------------K-----------------------------------AIEQ---------ATNT----GL-----V--------------------------------------------------------------------------------------F---------------VVAAG-N-SNI-----NA------------------CMTS---------------------------------------------------------------------------------------------------------------------------------------P-ASSKYA-------------------------------IT---VG--A------------------------------I---------------------------DDY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SV-TAF-----S--N--------W-GEC-V----------------------------------------------------------------------D-----I------F-----------------A-----S-------------G-----------------AY--------------------------------V------------------------------------------------------------------RS----------------------------------------------------------------------------------------------------------------------VDARNHDKT-QV----------------LSG------TSMASPIVT----G---------------------------M------------------VANLLS----------------Q--NVE-----------------------------------------------------------------SGK--------------I---------------------KSVL-------IRM-------------------------------------------------------------------------------------------------AAKNKITKTSLFLR----KKTPNRILYNGI-----QE 490
 491 -------------------------------YSYIYESDFIGK-------------------------------------------K-V--SA--------------Y--------------------VID---------------------------S--------------GIAI-G------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-GR-------------------------------------ARTGKDFT-------------------------DEGPG----------DNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLIG----SHT-----------------------------------------------------------------------YGV--AKG-V--QIIDV---KA---LNSK----------G-TG--S------------LST-------------------------------------I--------LVA--------------I-----------EF---AV----------------NHRLR------------S----------GRM--GV-----------------------------------------ANLSLG--AYKNK------LLN---------------------K-----------------------------------AIDQ---------ATQT----GL-----V--------------------------------------------------------------------------------------F---------------VVAAG-N-NNI-----NA------------------CLTS---------------------------------------------------------------------------------------------------------------------------------------P-SSSPYA-------------------------------IT---VG--A------------------------------I---------------------------DDY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SI-ASF-----S--N--------W-GEC-V----------------------------------------------------------------------D-----L------F-----------------A-----S-------------G-----------------AY--------------------------------V------------------------------------------------------------------KS----------------------------------------------------------------------------------------------------------------------VNIRSDFRP-SV----------------LSG------TSMAAPIVT----G---------------------------L------------------VANLLN----------------E--GVD-----------------------------------------------------------------PEL--------------I---------------------KGQL-------IEM-------------------------------------------------------------------------------------------------STKHRISKSSLFLK----KRTPNRIAYNGICFSYYQD 491
 492 --------QRMAGWNLVRINQRML---NIDGR-FSYKGSSDGT-------------------------------------------G-V--TV--------------Y--------------------VMD---------------------------S--------------GINT-D------H-------------V---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------ASWGVD----------------------------FVDD-PSPFT----DKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AALIG----GKT-----------------------------------------------------------------------FGV--AKK-V--HLVAV---RT---MNQN----------S-SG--K------------TDN-------------------------------------L--------ILA--------------I-----------EW---IT----------------KD-VQKHKEKK------P----------TYK--AI-----------------------------------------TNMSVG-TSRSA-------ALN---------------------A-----------------------------------AIAA---------AANA----SM-----L--------------------------------------------------------------------------------------F---------------VVSAG-NA-QT-----DA------------------CNAS---------------------------------------------------------------------------------------------------------------------------------------P-ASAEAA-------------------------------IT---VA--A------------------------------T----------------------------NA--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ID------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KFSSTF-----S--N--------F-GAC-V----------------------------------------------------------------------D-----I------L-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------QS----------------------------------------------------------------------------------------------------------------------AWINSKYSV-MS----------------MTG------TSQAAPHVT----G---------------------------V------------------ISRYLSFFRD------------ATGSIS-----------------------------------------------------------------PEA--------------V---------------------RDWV-------VGM-------------------------------------------------------------------------------------------------SSKDVVQE-IP---D---EDTPNKLLFLDC------- 492
 493 -----------AEWNLVRISEHK----RNLSQPYIYDSDA-GS-------------------------------------------D-A--YV--------------Y--------------------VID---------------------------D--------------GMNI-D------H-------------E---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AKWGWSAF-------------------------NGTSR----------LGE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------GGIIG----GKT-----------------------------------------------------------------------YGV--AKK-T--NLIAV---QV---LNEE----------G-RG--S------------ISS-------------------------------------L--------LSG--------------L-----------QW---VT----------------TNAKK------------Y----------KGR--SI-----------------------------------------INMSLGMKTGGVSS-SALDALN---------------------Q-----------------------------------AVDA---------VVAS----GV-----P--------------------------------------------------------------------------------------M---------------FAAAG-NWGDV-----DA------------------CDVS---------------------------------------------------------------------------------------------------------------------------------------P-ASNKNV-------------------------------YT---VG--A----------------------------------------------------------TNR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EM-TDY-----S--S--------Y-GKC-V----------------------------------------------------------------------Q-----I------L-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------LS----------------------------------------------------------------------------------------------------------------------SYIDSKTST-VR----------------MTG------TSMASPHVA----G---------------------------V------------------AALLIS----------------EIDNPT-----------------------------------------------------------------PQN--------------V---------------------YKKM-------TSL-------------------------------------------------------------------------------------------------ST----------------------------------- 493
 494 ------QQSGRLNWHLSRISSREKILNYGDRVQYTYSSSDDGA-------------------------------------------D-I--DV--------------Y--------------------VMD---------------------------S--------------GIYL-E------H-------------S---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-GR-------------------------------------AKWGMT----------------------------ANSI-YEGNG----DLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLVG----GKT-----------------------------------------------------------------------NGV--AKG-V--NIIAV---KV---FDMS----------G-QG--S------------AVN-------------------------------------I--------IEG--------------I-----------AW---IA----------------QD-VESKRKGR------K----------KRR--AV-----------------------------------------VNMSFGFTRAVN-------VVE---------------------G-----------------------------------ALTE---------LIAG----GT-----S--------------------------------------------------------------------------------------V---------------VVAAG-NS-FV-----SA------------------CRIC---------------------------------------------------------------------------------------------------------------------------------------P-ARMASV-------------------------------TT---VG--A------------------------------S----------------------------TI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TL-AWF-----S--N--------Y-GSC-V----------------------------------------------------------------------D-----I------I-----------------A-----P-------------G-----------------DE--------------------------------I------------------------------------------------------------------LG----------------------------------------------------------------------------------------------------------------------AGIEKPDTR-VR----------------QSG------TSMAAPIVA----G---------------------------V------------------AARFLSSFED------------DERWPT-----------------------------------------------------------------PAE--------------V---------------------QTYL-------IDH-------------------------------------------------------------------------------------------------GNQNFLDL-SN-------SGTPNVEVYS--------- 494
 495 ---------SGALWGLARITSTDWSIGNLRTE-FEYSEMNNGQ-------------------------------------------G-V--DV--------------Y--------------------IID---------------------------T--------------GIYE-G------H-------------D---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------VTWGYV----------------------------TKGLRNEGRV----DLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-V-----------------------ASLAA----GRV-----------------------------------------------------------------------YGV--AKK-A--NIIAV---KC---MDRS----------G-TG--S------------VGD-------------------------------------M--------IEA--------------V-----------EW---VH----------------KQI-----NTK------K----------ERK--HV-----------------------------------------VNMSFGMGGPNL-------ILE---------------------E-----------------------------------AIQA---------AIND----GV-----T--------------------------------------------------------------------------------------F---------------VIAAG-NS-AE-----DT------------------CETA---------------------------------------------------------------------------------------------------------------------------------------P-AKVSAA-------------------------------IT---VA--A------------------------------S----------------------------NS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ND------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EL-AYF-----T--N--------A-GPC-I----------------------------------------------------------------------N-----I------V-----------------A-----P-------------G-----------------EN--------------------------------V------------------------------------------------------------------IG----------------------------------------------------------------------------------------------------------------------ADIHSPNST-QV----------------HSG------TSFAAPYVA----G---------------------------V------------------IGVYLS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLPDT------------- 495
 496 -----------LGIAYIEQDAKVKPAEIWNLDRIDQTSNILDGTF-------NPS-GDGT--------------------------G-V--NV--------------Y--------------------LVD---------------------------T--------------GIYT-D------Y-------------S---------N--------------------------------F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANEPTDWIDIYSGRKAPVKGDCN--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-M-----------------------AGTIG----SMT-----------------------------------------------------------------------YGV--AKN-V--NLLSV---RI---FDCN----------G-DT--T------------WGY-------------------------------------V--------IDA--------------L-----------EY--ILA--------------------NSNPNIP----------------------SV-----------------------------------------INLSLSGGVSDAAN-A---------------------------------------------------------------AVNK---------LYDA----GI-----L--------------------------------------------------------------------------------------P---------------IVAAG-NG------------------------GINSCETS---------------------------------------------------------------------------------------------------------------------------------------P-ASAEKA-------------------------------LV---VGGLG------------------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AD---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EQV-----F--N--------Y-GQC-V----------------------------------------------------------------------D-----V------I-----------------A-----P-------------A-----------------IN--------------------------------I------------------------------------------------------------------ESLNFE------------------------------------------------------------------------------------------------------------------RTRKIPSVI-------------------ASG------TSSAAAHVT----G---------------------------A------------------AAII----LQ------------NNPNWT-----------------------------------------------------------------PVD--------------V---------------------ENFI-------KST-----------------------------------------------------------------------------------------------------ATTVTGLDNPILYGI------------------ 496
 497 -------------------------WGQDRIDQRDVQGDSKMI----------LE-GYGT--------------------------ETH---I--------------Y--------------------IID---------------------------T--------------GINA-D------H-------------P---------D--------------------------------FSG--------------RAFNVKDVIGGDGLD--------CN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------MH-M-----------------------AGIAA----SET-----------------------------------------------------------------------YGI--ANR-A--KVYGV---RA---LDCD----------G-VG--T------------MAD-------------------------------------V--------ISG--------------L-----------E----------------------------------WVANSG----------IRP--LL-----------------------------------------ISMALAG-PN---------------------------SQAMID------------------------------------AIAE---------AHQR----SS-----L--------------------------------------------------------------------------------------V---------------VVAAG-NA-------------------DD-----DACNTS---------------------------------------------------------------------------------------------------------------------------------------P-ANAPDA-------------------------------LT---IA--S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STVDDSRSFF-----S--N--------W-GEC-V----------------------------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------SN--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSLGVDGE-PST-------------------FSG------TSTACAHAI----G---------------------------A------------------ASAI----M-ENQHS-----------------------------------------------------------------------------------------------H------------------VGVIEQM-------KRTASMDK-------------------------------------------------------------------------------ISD-PKGTPNHL------------VY------------------------ 497
 498 ------W-------GLDRIDQASLPL---------------DGAY-------YYD-GYGT--------------------------G-V--TA--------------Y--------------------VVD---------------------------S--------------GVRG-S------H-------------T---------Q--------------------------------FRP--------------LLPPAQQPAAP-TAPRAV-SPSGPSRVQHGYSVFTATAGGLGGSGG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G------------DS-----------------------------------------------------------------------------------------D---C---------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLLG----GVD-----------------------------------------------------------------------YGV--AKN-V--TIVPV---QV---LDCN----------G-NT--S------------ETL-------------------------------------L--------KQG--------------L-----------EW---VG--------------------R-----N------L----------VLP--AV-----------------------------------------VHMSLE---------GGYS-AA--------------------VN--------------------------AMVD-----SLTA------------L----GA-----V--------------------------------------------------------------------------------------V---------------VASAG-NS--------NR---------DTCAVS----------------------------------------------------------------------------------------------------------------------------------------------P-ASAQ-S---------------------------A---VA---VA--A------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E-------------------------------------------------------------------------------------AD-------G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TR-WYR-----S--N--------C-APL-SPPPPPFPCVFVPQNLVVKGSCV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------VS--------------------------------L------------------------------------------------------------------LA-AVP-------------------------------------------------------------------------------------------------------------WTDS--------AS-GL----------------KTG------TSMAAPFAS----G---------------------------V------------------AA-L----YL----E-------SHPGAT-----------------------------------------------------------------PGD--------------V---------------------AQRL-------LRSALAGAVA------------------------------------------------------------------------------------------------------------------------------- 498
 499 ----ALW-------HLDRIDQRAPPLDGMYGFGP----------------------GTGA--------------------------G-V--TI--------------Y--------------------ALD---------------------------S--------------GVFA-Q------H-------------D---------E--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSWGTAPAAGSGAATAGRASYGHDFVDGDAE-----------------------------------------------------------------------------------AADCD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTAV----GRSV-----------------------------------------------------------------------GV--ARG-A--ELVAV---RV---LDCS----------G-SG--S------------IAD-------------------------------------T--------VAG--------------L-----------DW---LA--------------------K-----H------V----------KRP--AV-----------------------------------------AMLSLGVPAAALPV-QRRSCYW--------------------SSQQLSVSQLQILA-----ALAARDWSRVLGE-----AVSVLV--------SQH----GV-----P--------------------------------------------------------------------------------------V---------------VAASG-NA--------AV---------DSCGIT----------------------------------------------------------------------------------------------------------------------------------------------P-ANLP-E---------------------------V---IT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------LE-------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHIIASVPYT-ASY-----------------R-GSS-P----------------------------------------------------------------------DLHR--L------------------------G-----P-------------P-----------------CF----------------------MFKLGDRCPAV------------------------------------------------------------------TA----------------------------------------------------------------------------------------------------------------------------SAY-TW----------------ASG------TSMAVP--------------------------------------------------------------------A-------SHPDAS-----------------------------------------------------------------PRE--------------V---------------------AAAL-------TRG-------------------------------------------------------------------------------------------------------ATLGALQDPRMRPGTPNRLL----------- 499
 500 ------W-------AVDRVDQVS-SVLDNQPYTP-C--------------------ECGN--------------------------G-V--DV--------------Y--------------------VLD---------------------------T--------------GIRY-N------H-------------C---------E--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRALYPGYDPVDNYNGGNRQ------------GG-----------------------------------------------------------------------------------------D---C---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLAV----GNV-----------------------------------------------------------------------SGL--ARC-A--TAYSV---RV---LDCN----------G-RG--P------------YSV-------------------------------------I--------IDG--------------L-----------NY---VA------------GRIRSSN-------R-----------------T----GV-----------------------------------------ISMSLG-------------GSF--------------------SS--------------------------SLDQ-----VVTN---------VVSQ----GI-----P--------------------------------------------------------------------------------------V---------------VASAG-ND--------RG---------N----A---CSKS---------------------------------------------------------------------------------------------------------------------------------------P-ASNP-G---------------------------A---IT---VA--G------------------------------S-----------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------GD-------N-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-YFN-----T--N--------A-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------AS--------------------------------V------------------------------------------------------------------TA-ASH-----------------------------------------------------------------------------------------------SCSTCSCLRT-------------------------------------LSG------TSMAAPLVS----G---------------------------G------------------IA-L----LL----E-------KEPSLS-----------------------------------------------------------------PAA--------------I---------------------SNRL-------KQN---------------------------------------------------------------------------------------------------CIKNAISYTNLPVTYRSNTNNCLLHV--------- 500
 501 -----SW-------AVDRVDQVS-SVLDNKPYTP-C--------------------ECGN--------------------------G-V--DV--------------Y--------------------VLD---------------------------T-------VNLCIIIGIRY-D------H-------------C---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GRTKYSDYVFDGGRAKYSGYDPIDNYNDTNLE------------GR-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLAV----GNV-----------------------------------------------------------------------SGL--ARC-A--TAYSV---RV---LDCN----------G-RG--P------------YSV-------------------------------------I--------IDG--------------L-----------NY---AA------------IRIKDSN-------R-----------------P----AV-----------------------------------------IVMSLG-------------GSF--------------------SS--------------------------SLDQ-----VVTN---------VINQ----GI-----P--------------------------------------------------------------------------------------V---------------VASAG-NN--------RG---------N----A---CSRS---------------------------------------------------------------------------------------------------------------------------------------P-ASNP-G---------------------------A---IT---VG--S------------------------------T-----------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------GD-------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-NYN-----T--N--------A-G---P--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------AY--------------------------------V------------------------------------------------------------------TA-ASH-----------------------------------------------------------------------------------------------TCSSCSCTKV-------------------------------------VSG------TSMAAALVS----G---------------------------A------------------VA-L----LL----E-------NEPFLS-----------------------------------------------------------------PDS--------------I---------------------ADEL-------KYD---------------------------------------------------------------------------------------------------CLKNAI----------------------------- 501
 502 HGSDVSW-------AVDRIDQVS-SVIDGEPYTP-C--------------------HCGK--------------------------G-V--DI--------------Y--------------------VLD---------------------------S--------------GVNY-D------H-------------C---------E--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRAKYPGYDPVDNYLNTNNR------------GK-----------------------------------------------------------------------------------------D---C---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLAV----GKN-----------------------------------------------------------------------YGV--ARC-A--NVYSV---RV---LRCD----------N-GA--P------------WSV-------------------------------------V--------IDG--------------L-----------NY---AA------------RKITEKNPR-----R-----------------P----SI-----------------------------------------ISLSLG-------------GGY--------------------QQ--------------------------SVDQ-----LVTS---------IISQ----GI-----T--------------------------------------------------------------------------------------V---------------VVAAG-ND--------RS---------N----A---CSST---------------------------------------------------------------------------------------------------------------------------------------P-ASNS-A---------------------------A---IT---VA--G------------------------------T-----------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------GD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-YYN-----T--N--------A-G---P--------------------CI------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------EG-ASY-----------------------------------------------------------------------------------------------SCNTCQCLKT-------------------------------------FSG------TSMATPMVS----G---------------------------A------------------AA-L----LL----Q-------ENPSLS-----------------------------------------------------------------PAS--------------I---------------------VQKL-------KQD---------------------------------------------------------------------------------------------------CLKNVIDFSYLPSQYRSNTNNCLLHVKSCNNTCDG 502
 503 ------W-------AIDRLDQTG-PTLDNT-YTP-E--------------------GNGE--------------------------G-V--DV--------------Y--------------------ILD---------------------------T--------------GIKY-S------H-------------N---------D--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRAKYPGFDPVDTADGTNQN------------GL-----------------------------------------------------------------------------------------D---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASLAV----GTN-----------------------------------------------------------------------WGV--AKG-A--DVYSV---RV---LDCE----------G-SA--P------------WSV-------------------------------------I--------VNG--------------V-----------NK---AG------------SRIVSSN-------R-----------------S----GV-----------------------------------------ISMSLG-------------GGY--------------------SH--------------------------TLNS-----ALIS---------VMNK----GV-----P--------------------------------------------------------------------------------------V---------------VAAAG-NE--------RD---------D----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-ASTT-G---------------------------V---IT---VG--G------------------------------S-----------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------GD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L-YYY-----T--N--------G-G---T--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------SQ--------------------------------V------------------------------------------------------------------TA-ADS-----------------------------------------------------------------------------------------------SCNSCSV--T-------------------------------------YSG------TSMATPIVS----G---------------------------S------------------VA-I----HL----Q-------KNPALT-----------------------------------------------------------------PSQ--------------V---------------------RNKI-------IQD---------------------------------------------------------------------------------------------------SLKNKLTYNNLKNSLRSGTANRLLH---------- 503
 504 ------W-------ALDRINQQNNNKLDG--YTNYN--------------------GDGQ--------------------------G-V--AI--------------Y--------------------ILD---------------------------S--------------GINY-E------H-------------C---------E--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRAMFSGYDPVDKIMGTNYK------------GR-----------------------------------------------------------------------------------------D---C---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAA----GAS-----------------------------------------------------------------------SGV--ASK-A--KVYSV---RV---LDCD----------N-RI--P------------WSA-------------------------------------V--------IDG--------------L-----------NH---VG------------EKITEAKAG-----K------N----------P----SV-----------------------------------------ILLPLS-------------GPV--------------------SL--------------------------GMDH-----TLEK---------LLNQ----NI-----P--------------------------------------------------------------------------------------I---------------VAAGG-ND--------GG---------D----A---CSKS---------------------------------------------------------------------------------------------------------------------------------------P-ASTP-G---------------------------V---IT---VS--A------------------------------S-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------GD-------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-SST-----T--N--------A-G---P--------------------CI------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------VG-ANH-----------------------------------------------------------------------------------------------SCTGCECKSI-------------------------------------RSG------TSVSSGLVA----G---------------------------V------------------VS-L----YL----Q-------ESPRLT-----------------------------------------------------------------PSE--------------V---------------------RDKL-------LNS---------------------------------------------------------------------------------------------------CTRNTLHFESLPQHLSGLTNNCLLYI--------- 504
 505 -------------------------------SP--TRTG-----K-----------------------------------------G-V--DA--------------Y--------------------IAD---------------------------S--------------GINF-D------H-------------E---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGRAKYLGYDPYDEYQHFFSRFHQHGWDCNGHG-------TH-V-----------------------ASLLG----GAK-----------------------------------------------------------------------FGS--AKS-V--SLFSV---RV---LGCS----------NRAP---------------WSV-------------------------------------V--------LDG--------------LDHIMKMVSVRKRP------------------------------------------------------SI-----------------------------------------INLSLS----------------------------------------------------------------GSYQQSMNNAVQKLS-------------EAGV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NGDEA--ACLNS-------------------------------------------------------------------------------------------------------------------------------------------------------------PASSI--------H---------------------A---IT---V---G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTDENNQLYSHTNYGLCVD----------------------------------------------------------------------------I------F-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------QGAHYKCG--------------------------------------------------------------------------------------------------------------------------VSSIEYPDEVRENGCSFLLTG------TSMSTPLVG----G---------------------------V------------------VAGM----LE------------ERPLLK--------------------------------------------------------------------------------------------------------PNEVLSLL-------------------------------------------------------------------------------------------------------------------------------------------- 505
 506 ------TQDPTIPWHLDLLDQDPAAYFDHQYSP--TRTG-----K-----------------------------------------G-V--DA--------------Y--------------------IAD---------------------------S--------------GINF-D------H-------------E---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGRAKYLGYDPYDEYQHFFSRFHQHGWDCNGHG-------TH-V-----------------------ASLLG----GAK-----------------------------------------------------------------------FGS--AKS-V--SLFSV---RV---LGCS----------NRAP---------------WSV-------------------------------------V--------LDG--------------LDHIMKMVSVRKRP------------------------------------------------------SI-----------------------------------------INLSLS----------------------------------------------------------------GSYQQSMNNAVQKLS-------------EAGV-----V--------------------------------------------------------------------------------------V---------------VAAAG-NGDEA--ACLNS-------------------------------------------------------------------------------------------------------------------------------------------------------------PASSI--------H---------------------A---IT---V---G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GTDENNQLYSHTNYGLCVD----------------------------------------------------------------------------I------F-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------QGAHYKCG--------------------------------------------------------------------------------------------------------------------------VSSIEYPDEVRENGCSFLLTG------TSMSTPLVG----G---------------------------V------------------VA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 506
 507 ------W-------HLDRLDQLTLPL--------------DLGKF-------QRN-GEGS--------------------------S-V--DV--------------Y--------------------VLD---------------------------S--------------GIRY-S------H-------------E---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RATWSGYDAFDPDGTNQGTLFSGLTRISVFQGA-----------------------------------------------------------------------------------------D---L---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TH-V-----------------------AALVG----GRR-----------------------------------------------------------------------FGV--ARG-V--RLRSV---RV---LDDL----------G-NG--D------------SST-------------------------------------I--------LLG--------------I-----------NH---VA--------------KQVNS-S-----P------A----------GRR--SV-----------------------------------------VVMSLR---------GSRNVGN--------------------AS--------------------------TLNQ-----MARELV--------VAT----GT-----P--------------------------------------------------------------------------------------V---------------VAAAG-ND--------GR---------D----A---CKFV---------------------------------------------------------------------------------------------------------------------------------------P-GSED-E---------------------------V---IT---VG--G------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------VD-------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TYRRT-----------------N--------F-G---R--------------------CV------------------------------------------------D-----I------L-----------------A-----P-------------A-----------------AR--------------------------------V------------------------------------------------------------------RS-AGA-----------------------------------------------------------------------------------------------ECDT----------------------CS-RV----------------SSG------TSQAAPLVA----G---------------------------V------------------VV-A----ML----D-------DDPSLT-----------------------------------------------------------------PAQ--------------I---------------------RMKL-------LEDAVSDRIDLSRLPRDMRLQTANKLLHIPAR-SAFQ-----------------------------------------------------PRVTPA-CRTVWSIKSGGADGDLSSVACNVNETIMGCSSLAADEGMR 507
 508 KQQAVPW-------HLDRIDQKDLPV--------------N-GQF-------SAT-GDGS--------------------------G-V--DV--------------Y--------------------VLD---------------------------S--------------GIRY-S------H-------------E---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RASFAGFDAFDPAGTNQGL-------------------------------------------------------------------------------------------------------D---I---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AALVG----GKT-----------------------------------------------------------------------YGV--ARN-V--QLRSV---RV---LDEN----------G-RG--R------------GST-------------------------------------I--------LAG--------------L-----------NY---VR--------------MQVNQNP-----N------A------------R--AI-----------------------------------------AVMSLA---------GS----S--------------------MT--------------------------TVNM-----AAKELV--------H-T----GC-----A--------------------------------------------------------------------------------------V---------------FAAAG-NA--------NR---------D----A---CRFS---------------------------------------------------------------------------------------------------------------------------------------P-AGEA-E---------------------------V---IT---VG--G------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------VD-------G--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYRRTVNGRL-RG------T--N--------Y-G---R--------------------CV------------------------------------------------D-----I------M-----------------A-----P-------------A-----------------QE--------------------------------V------------------------------------------------------------------IS-ADV-----------------------------------------------------------------------------------------------ACDT----------------------CN-RE----------------LSG------TSQATPLVA----G---------------------------V------------------AA-T----ML----Q-------QDNSLT-----------------------------------------------------------------PAQ--------------L---------------------RMKL-------LFDAARNKIDFTPIPDDMKHMTPNKLLYIPQS-SAFT-----------------------------------------------------SGVTPT-CRTVWSIKSDVTDGALASVRCNINESMMGCSSVS-DDGLR 508
 509 --------------------------------------------Q-------RPA-FDGA--------------------------S-V--DV--------------Y--------------------IVD---------------------------S--------------GIRY-S------H-------------E---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RAGWSGFDAFDADGSNKGN-------------------------------------------------------------------------------------------------------D---L---------------------Y--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AALVG----GKT-----------------------------------------------------------------------FGV--NPR-V--LLRSV---RV---LNHR----------G-LG--S------------MLS-------------------------------------V--------LSG--------------I-----------NH---IY--------------DNITANS-----P------A------------R--GV-----------------------------------------LVMSLS---------SK---GV--------------------TQ--------------------------SVNE-----ASRRLV--------L-Q----GL-----P--------------------------------------------------------------------------------------V---------------VVAAG-NA--------GD---------D----A---CNRS---------------------------------------------------------------------------------------------------------------------------------------P-AGEA-E---------------------------V---IT---VG--G------------------------------T-----------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------TD-------H--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYDHV------SGA-----T--A--------H-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------A-----------------QE--------------------------------V------------------------------------------------------------------LS-AGA-----------------------------------------------------------------------------------------------ECDS----------------------CS-EI----------------RSG------TSMAAPITA----G---------------------------V------------------VA-K----LL----S-------RDPNMT-----------------------------------------------------------------PAQ--------------I---------------------RMAL-------LSAA------------------------------------------------------------------------------------------------------------------------------------- 509
 510 ---------------------HCGCL--------------DCVDY-------R----NTD--------------------------S-V--DV--------------Y--------------------IVD---------------------------S--------------GIRY-S------H-------------E---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RADWSGFDAHDADGSNKGN-------------------------------------------------------------------------------------------------------D---L---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AALVG----GKT-----------------------------------------------------------------------FGV--NPR-V--LLRSV---RV---LNHR----------G-LG--S------------TLT-------------------------------------V--------LDG--------------L-----------NH---IY--------------DKITANS-----P------A------------R--GV-----------------------------------------VVMSLS---------SA---GV--------------------SR--------------------------SVNQ-----ASRQLV--------L-Q----GL-----P--------------------------------------------------------------------------------------V---------------VVAAG-ND--------GD---------D----A---CTRS---------------------------------------------------------------------------------------------------------------------------------------P-AGEA-E---------------------------V---IT---VG--G------------------------------T-----------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------TD-------H--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LYDRTDQTPP-GGA-----T--A--------H-G---S--------------------CV------------------------------------------------D-----I------F-----------------A-----P-------------A-----------------QE--------------------------------V------------------------------------------------------------------LS-AGA-----------------------------------------------------------------------------------------------ECDS----------------------CS-AV----------------LSG------TSMAAPITA----G---------------------------V------------------VT-K----LL----S-------RDPSIT-----------------------------------------------------------------PAQ--------------I---------------------RMAL-------LSAAASDKLDFSSLPKDSLLKTPNKLLQLPEV-PLEE--------------------------------------------------------TAG-CRTVWSVKSDPEKGSPVGAACNANETLLSCSSFT--DGVH 510
 511 EAQTAPW-------GLDRVDQTELPL--------------D-GKY-------QVG-GDGS--------------------------G-I--DV--------------Y--------------------VLD---------------------------T--------------GIRY-T------H-------------D---------E--------------------------------F---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGNNGTTRATWSGYDAF--GNGNNGA-------------------------------------------------------------------------------------------------------D---C---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVG----GKN-----------------------------------------------------------------------SGV--APG-V--NLLSV---RV---LDCN----------G-KG--Q------------ASI-------------------------------------I--------LEG--------------M-----------NW---VL--------------SKIKQKG-----T------A----------NKK--TV-----------------------------------------VVLSLA---------GQ----F--------------------RQ--------------------------SVNN-----AAKRLV--------E-E----GV-----I--------------------------------------------------------------------------------------V---------------IAAAG-NY--------KR---------D----A---CRYS---------------------------------------------------------------------------------------------------------------------------------------P-ASEP-E---------------------------V---IT---VG--A------------------------------T-----------------------------K------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------DD-------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VYNLG------SFG-----T--N--------Y-G---G--------------------CL------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------QH--------------------------------V------------------------------------------------------------------HS-AAH-----------------------------------------------------------------------------------------------NCDD----------------------CH-HV----------------MSG------TSQATPHVA----G---------------------------S------------------AA-L----LL----Q-------SNPSYT-----------------------------------------------------------------PVD--------------I---------------------RRLL-------LQRSTKDKLDFGHIPSVARPLTPNKLLYVPNL-GRIM-----------------------------------------------------SGSESVFCRSVWSALSDRHSTATAVVRCSPQETMTSCSSLS-KNNNR 511
 512 -------------WGLDRINQRLLPLDSDYLTPRCVVTKVCTALD-----------------------------------------A-P--NI--------------Y--------------------LID---------------------------T--------------GILY-T------H-------------E---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EGRAKP----HYDH----FPDEGYNGIDIEGHG-------TH-V-----------------------AGIAG----GKT-----------------------------------------------------------------------FGV--SKN-A--NLWSV---RI---FNKD----------GVAT---------------SKG-------------------------------------I--------WHG--------------LLSVFND---GQLP------------------------------------------------------AV-----------------------------------------INLSIV----------------------------------------------------------------SASSLLDK--FGTLI-------IRNIQNRDRI-----P--------------------------------------------------------------------------------------V---------------IVAAG-NKDSD--AGDYW-------------------------------------------------------------------------------------------------------------------------------------------------------------PANS---------N---------------------I---VT---VV--G----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATDSNDVRATFSNVGEYVN----------------------------------------------------------------------------L------F-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------ESAGIGS---------------------------------------------------------------------------------------------------------------------------------------DTEVVTKSG------TSMSTPYVT----G---------------------------I------------------ASRI----KT------------QVPGAT--------------------------------------------------------------------------------------------------------AEEVLFKMNYFATKDVVVD--------AAGTPNRLFY--------------------------------------------------------------------------------------------------------------- 512
 513 ----AIQTTPVTQWGLSRISHKKAQTGNYAYV------RETVG-----------K-H-----------------------------P-T--VS--------------Y--------------------VVD---------------------------S--------------GIRT-T------H-------------S---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-GR-------------------------------------AVWGA-------------------------------NFADTQNA----DLL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGTVG----GKT-----------------------------------------------------------------------YGV--DAN-T--KLVAV---KV---F---------------AG--R------------SAA-------------------------------------LSVINQGFTWAL--------------N-----------DY---IS----------------K--------RD------T----------LPR--GV-----------------------------------------LNFSGG-GPKSA-------SQD---------------------A-----------------------------------LWSR---------ATQE----GL-----L--------------------------------------------------------------------------------------V---------------AIAAG-ND-AV-----DA------------------CNDS---------------------------------------------------------------------------------------------------------------------------------------P-GNIGGS---------------------------TSGIIT---VG--S------------------------------I----------------------------DS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KI-SVWSGGQGS--N--------Y-GTC-V----------------------------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------IS----------------------------------------------------------------------------------------------------------------------ASYQSDSGT-LV----------------YSG------TSMACPHVA----G---------------------------L------------------ASYYLS---I------------NDEVLT-----------------------------------------------------------------PAQ--------------V---------------------EALI-------TES-------------------------------------------------------------------------------------------------NTGVLPTTNL--------KGSPNAVAYNGVGI----- 513
 514 ----------------------------------------------------------GM--------------------------G-I--DV--------------Y--------------------VLD---------------------------T--------------GVYV-D------H-------------L---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNRA-------------------------------------LH-----S-------------------------INLIQHED---------QSDMG------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AAKIA----GTE------------------------------------------------Y-----------------------GV--SKA-A--NIRSV---KILNKLGDG----------------S------------TST-------------------------------------L--------LKG--------------I-----------------E--------------------------------------------HVI--QV-----------------------------------------ATPGKSLIN-------------------------------------------------------------------------------LSL-SGPH----SR-----L--------------------------------------------------------------------------------------IDDAIDTLVLKYNIPVFAAAG-NAG----------------------------TDACFFTPSSN-------------------------------------------------------------------------------------------------------------------------------PNV------------------------------------FS---VG--A------------------------------IDIQDRV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TRY-----S--D--------V----------------------------------------------------------------------------GECVS-I------Y-----------------A-----P-------------G-----------------SA--------------------------------I------------------------------------------------------------------VS-AY-----------------------------------------------------------------------------------------------------VGGNDSSKSMD---------------------------------G------TSMASPHVA----G---------------------------T------------------AANM----MS------------KKSFST-----------------------------------------------------------------PHA--------------L---------------------YDAL-------RSL----------------------------------------------------------------------------------AT-------------------------------------------------- 514
 515 ----------------------------------------------------YDR-NDAT--------------------------D-V--TI--------------F--------------------ILD---------------------------T--------------GVLF-T------H-------------D---------E--------------------------------F---------------------T----------------N----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------FY------NDTVT--------PNSPI------------MV-----------------------------------------------------------------------------------------D---V---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------ASVAA----GAN----------------------------------------------------I-------------------GV--AQG-A--TVESI---RV---AGSD----------G-LA--A------------ADD-------------------------------------V--------LAG--------------L----------------------------DDVQRWWNNNP-----G------S----------K----CV-----------------------------------------VSYSLI-------S-TSF---S---------------------T--------------------------TLNY-----AFGN-L-------SANT----DC-----V--------------------------------------------------------------------------------------V---------------VVAAG-NQ--------GADI----SMAD----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--G-S----PD---------------------V---IT---VG--G------------------------------SRN------------------------RMNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-IGI-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------Y-----------------A-----P-------------A-----------------RN--------------------------------I------------------------------------------------------------------DL-AAP-----------------------------------------------------------------------------------------------S--------G----SSNS--------NY-LR----------------SSG------TSFATPAVA----G---------------------------A------------------AAMI----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 515
 516 ------------------IDQVDLPR---------------DGAS-------YDR-NDAT--------------------------D-V--TI--------------F--------------------ILD---------------------------T--------------GVLF-T------H-------------D---------E--------------------------------F---------------------T----------------N----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------FY------NDTVT--------PNSPI------------MV-----------------------------------------------------------------------------------------D---V---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------ASVAA----GAN----------------------------------------------------I-------------------GV--AQG-A--TVESI---RV---AGSD----------G-LA--A------------ADD-------------------------------------V--------LAG--------------L----------------------------DDVQRWWNNNP-----G------S----------K----CV-----------------------------------------VSYSLI-------S-TSF---S---------------------T--------------------------TLNY-----AFGN-L-------SANT----DC-----V--------------------------------------------------------------------------------------V---------------VVAAG-NQ--------GADI----SMAD----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--G-S----PD---------------------V---IT---VG--G------------------------------SRN------------------------RMNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-IGI-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------Y-----------------A-----P-------------A-----------------RN--------------------------------I------------------------------------------------------------------DL-AAP-----------------------------------------------------------------------------------------------S--------G----SSNS--------NY-LR----------------SSG------TSFATPAVA----G---------------------------A------------------AAMI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 516
 517 ----------------------------------------------------YDR-NDAT--------------------------D-V--TI--------------F--------------------ILD---------------------------T--------------GVLF-T------H-------------D---------E--------------------------------F---------------------T----------------N----------------------G------------------------------RVS----------------------------------------------------------------------------------------------------------------------------------FY------NDTVT--------PNSPI------------MV-----------------------------------------------------------------------------------------D---V---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------ASVAA----GAN----------------------------------------------------I-------------------GV--AQG-A--TVESI---RV---AGSD----------G-LA--A------------ADD-------------------------------------V--------LAG--------------L----------------------------DDIQRWWNSNP-----G------S----------K----CV-----------------------------------------VSYSLI-------S-TSF---S---------------------T--------------------------TLIY-----AFGN-F-------SKNT----DC-----V--------------------------------------------------------------------------------------V---------------VVAAG-NQ--------GSHF----SEAN----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--G-S----PN---------------------V---IT---VG--G------------------------------SRA------------------------RQNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------SD-------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-IGI-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------Y-----------------A-----P-------------A-----------------RN--------------------------------I------------------------------------------------------------------DL-AAP-----------------------------------------------------------------------------------------------S--------G----SSNS--------NY-LR----------------SSG------TSFATPAVA----G---------------------------A------------------AAMI----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 517
 518 LPNPPVN-------LLDRIDQASLPF---------------DGAP-------YDR-NDAT--------------------------D-V--TI--------------F--------------------ILD---------------------------T--------------GVLF-T------H-------------D---------E--------------------------------F---------------------T----------------N----------------------G------------------------------RVR----------------------------------------------------------------------------------------------------------------------------------FY------NDTVT--------PNSPF------------MV-----------------------------------------------------------------------------------------D---V---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------ASTAA----GAN----------------------------------------------------I-------------------GV--AQG-A--TVESI---RV---AGSD----------G-LA--A------------AND-------------------------------------V--------LAG--------------L----------------------------DDVQRWWNKNP-----G------S----------K----CV-----------------------------------------VSYSLI-------S-TSF---S---------------------T--------------------------TLNY-----AFGN-V-------SKNT----DC-----V--------------------------------------------------------------------------------------V---------------VVAAG-NQ--------GSDV----SQAD----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--G-S----PH---------------------V---IT---VG--G------------------------------SRF------------------------RQNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-IGI-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------Y-----------------A-----P-------------A-----------------RN--------------------------------I------------------------------------------------------------------DL-AAP-----------------------------------------------------------------------------------------------S--------G----SSNS--------HY-LR----------------SSG------TSFATPAVA----G---------------------------A------------------AAMI----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 518
 519 LPNPPVN-------LLDRIDQASLPF---------------DGAP-------YDR-NDAT--------------------------D-V--TI--------------F--------------------ILD---------------------------T--------------GVLF-T------H-------------D---------E--------------------------------F---------------------T----------------N----------------------G------------------------------RVR----------------------------------------------------------------------------------------------------------------------------------FY------NDTVT--------PNSPF------------MV-----------------------------------------------------------------------------------------D---V---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------ASTAA----GAN----------------------------------------------------I-------------------GV--AQG-A--TVESI---RV---AGSD----------G-LA--A------------AND-------------------------------------V--------LAG--------------L----------------------------DDVQRWWNKNP-----G------S----------K----CV-----------------------------------------VSYSLI-------S-TSF---S---------------------T--------------------------TLNY-----AFGN-V-------SKNT----DC-----V--------------------------------------------------------------------------------------V---------------VVAAG-NQ--------GSDV----SQAD----A---CNYS---------------------------------------------------------------------------------------------------------------------------------------P-S--G-S----PH---------------------V---IT---VG--G------------------------------SRF------------------------RQNG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------M-------------------------------------------------------------------------------------SD-------D-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-IGI-----S--N--------Y-G---P--------------------CV------------------------------------------------D-----I------Y-----------------A-----P-------------A-----------------RN--------------------------------I------------------------------------------------------------------DL-AAP-----------------------------------------------------------------------------------------------S--------G----SSNS--------HY-LR----------------SSG------TSFATPAVA----G---------------------------A------------------AAMI----LS----T-------TSLTPT-----------------------------------------------------------------GRKTMTDLVLDILVATSS---------------------KDKL-------RSL------------------------PS------------------------------------------------------------------------------------------------------------ 519
 520 ------------------------PWNRDRIDQVDLPLDMQHF----------ET-SGGE--------------------------GTT---I--------------F--------------------IMD---------------------------T--------------GVRV-D------H-------------T---------E--------------------------------FNG--------------RAEYYRDMLASDPTN--P-ETGDPN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------AGAAI----GAT-----------------------------------------------------------------------IGV--ATK-A--NVKSI---RV---AGPT----------G-SG--S------------IEQ-------------------------------------S--------LLG--------------F-----------EE---VE--------------------------KWTIANPG----------AK---CV-----------------------------------------VSYSLSSHGI---------------------------STSLDT------------------------------------AVAK---------LSQK-----C-----V--------------------------------------------------------------------------------------V---------------VISAG-NY-------------------GQDPETADACKYS---------------------------------------------------------------------------------------------------------------------------------------P-GRAPEA-------------------------------IT---VG--A------------------------------A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RLRQGATVDDKAG-F-----S--C--------S-GSC-L----------------------------------------------------------------------T-----L------Y-----------------A-----P-------------G-----------------HK--------------------------------V------------------------------------------------------------------TV------------------------------------------------------------------------------------------------------------------ASSVSVDGV--VT-------------------SSG------TSFSAPAVA----G---------------------------A------------------AAVL----L-SNGYD-----------------------------------------------------------------------------------------------I------------------YEVKDVI-------RNTAIKNK-------------------------------------------------------------------------------LSGLPAGDETNL---------LLNVQNSAFHQPKP--------------- 520
 521 ----------------------------------------------------------GR--------------------------D-V--NI--------------Y--------------------VID---------------------------S--------------GIRD-T------H-------------V---------D--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Q-------------------------RNGVSRVV----HLE--DIIGG-----AGFGTDCL-----------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------ASVAA----GGS-----------------------------------------------------------------------YGV--SNQ-A--SLFDV---RIFN-CVDG---------------TY------------LSH-------------------------------------L--------EYA--------------I--------------------------------------------TAILDS-G----------SPP--GI-----------------------------------------IVMSVTAFA-------------------------------------------------------------PAYDDEYVPWITSFN-ALATQ-AVNA----GH-----I--------------------------------------------------------------------------------------L---------------VTGAG-ND------------------------ADFAEYYL---------------------------------------------------------------------------------------------------------------------------------------PASSGF-----------------------------V---IT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKKDKI-CGF-----S--N--------I-GYA-V----------------------------------------------------------------------D-----L------Y-----------------A-----P-------------G-----------------YA--------------------------------L------------------------------------------------------------------PSASHT-----------------------------------------------------------------------------------------------------------------------GDTEVVL----------------RSG------TSFSAPLVA----G---------------------------L------------------CASL----LG----------------------------------------------------------------------------------------------------V---------------------NDTL-------NHSAMLDKILEDATDGALINV-------------------------------------------------------------------------------------------------------------------- 521
 522 ----------------------GHITPPHLDRIDQQLLPLDGATY-------EPL-NNGD--------------------------G-V--EV--------------Y--------------------IID---------------------------S--------------GIME-D------H-------------E---------E--------------------------------F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGRVKLVPDHSEKCDFMQGQAASDAAFSV-CG-----------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TA-M-----------------------AGIVG----GNT-----------------------------------------------------------------------YGV--AKG-V--TMWDV---RVLTGTCDG------------RTYDY------------LSD-------------------------------------V--------IHG--------------M--------------------------------------------DMVLFSGG----------AKP--AV-----------------------------------------VLI-----A-------------------------------------------------------------SGTQNEYVS--VSYN-TATNR-LYDQ----GY-----V--------------------------------------------------------------------------------------V---------------VGAAG-NA------------------------RRDACNFL---------------------------------------------------------------------------------------------------------------------------------------AGGSDH-----------------------------V---FT---VG--Q------------------------------S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHPPLAPMDMA-LD------G--N--------Y-GAC-V----------------------------------------------------------------------D-----I------F-----------------A-----P-------------G-----------------YS--------------------------------V------------------------------------------------------------------QTAGTE-----------------------------------------------------------------------------------------------------------------------TTTITQT----------------VTG------TSASAAVVA----G---------------------------A------------------AAVM----L-----------------------------------------------------------------------------------------------------V---------------------HDVT-------NQTP--DYVMESIRNRATT---------------------------------------------------------------------------------------------------------------------- 522
 523 FAQSIPW-------NLGRIVPPLPGT--------------D--TY-------SPP-NEGD--------------------------K-V--QI--------------Y--------------------LLD---------------------------T--------------SVQS-T------H-------------R---------E--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AG-----RVLITDFQNVPEEDSSRFH----------RQAS-----------------------------------------------------------------------------------------K---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-M-----------------------AGVLS----GRD-----------------------------------------------------------------------AGV--ARG-A--HIHSL---RV---LNCQ----------G-KG--T------------VSG-------------------------------------A--------LIG--------------L-----------EF---VR--------------ASLEAQP-----S------P------------P--LV-----------------------------------------VLLPFT---------GA----H--------------------SR--------------------------VLNA-----GCRRMV--------Q-M----GA-----V--------------------------------------------------------------------------------------V---------------VVAAG-NY--------KD---------D----A---CLYS---------------------------------------------------------------------------------------------------------------------------------------P-ASEP-E---------------------------V---IT---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------ED-------R--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASIS------TLG-----T--N--------F-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------IG-ASS-----------------------------------------------------------------------------------------------DCST----------------------CF-TA----------------RSG------TSQAAAHVA----G---------------------------V------------------AA-M----LL----S-------AEPHLS-----------------------------------------------------------------AAE--------------L---------------------RQRL-------LHLATKNVISTAWFPEEQRLQTPSSIVGLPAQLGPGE-----------------------------------------------------GWGWQLLCRSVWSARSGPTRHTTAVARCAGTEELLGCSSFS-HSGWR 523
 524 FAQSIPW-------NLQRVLQNKHEA--------------G--KY-------SPP-NDGA--------------------------K-V--GV--------------Y--------------------LLD---------------------------T--------------SVQL-T------H-------------R---------E--------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ED-----RVMVTDFNRVPEEDGVRVH----------RQAS-----------------------------------------------------------------------------------------Q---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-I-----------------------AGVIS----GRD-----------------------------------------------------------------------SGV--ARG-A--SVNSV---RV---LNCQ----------G-KG--T------------VSG-------------------------------------A--------LAG--------------L-----------EY---IQ--------------SSLASQP-----V------S------------P--VI-----------------------------------------LLLPFV---------GG----F--------------------SR--------------------------TLNT-----ACRKIV--------E-S----GA-----V--------------------------------------------------------------------------------------L---------------IAAAG-NY--------ND---------D----A---CLYS---------------------------------------------------------------------------------------------------------------------------------------P-ASEP-E---------------------------V---IT---VG--A------------------------------V-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F-------------------------------------------------------------------------------------AD-------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PLNRG------TTG-----T--N--------V-G---R--------------------CV------------------------------------------------D-----V------F-----------------A-----P-------------G-----------------DD--------------------------------I------------------------------------------------------------------IS-ASS-----------------------------------------------------------------------------------------------DCPT----------------------CF-TT----------------KSG------TSQAAAHVA----G---------------------------V------------------AA-V----LL----N-------LRPNSS-----------------------------------------------------------------SAE--------------V---------------------LQQL-------RYHSVKQVINPESLPVMHRLTTPNMVVALPDP--TST-----------------------------------------------------LTGEDLLCRSVWSERSASPVFSTAVSRCRSTEEMLSCSSFS-DNGMR 524
 525 FAQSIPW-------NLERITPPRYRA--------------D--EY-------QPP-DGGS--------------------------L-V--EV--------------Y--------------------LLD---------------------------T--------------SIQS-D------H-------------R---------E--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RVMVTDFENVPEEDGTRFH----------RQAS-----------------------------------------------------------------------------------------K---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-L-----------------------AGVVS----GRD-----------------------------------------------------------------------AGV--AKG-A--SMRSL---RV---LNCQ----------G-KG--T------------VSG-------------------------------------T--------LIG--------------L-----------EF---IR--------------KSQLVQP-----V------G------------P--LV-----------------------------------------VLLPLA---------GG----Y--------------------SR--------------------------VLNA-----ACQRLA--------R-A----GV-----V--------------------------------------------------------------------------------------L---------------VTAAG-NF--------RD---------D----A---CLYS---------------------------------------------------------------------------------------------------------------------------------------P-ASAP-E---------------------------V---IT---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------QD-------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVTLG------TLG-----T--N--------F-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------ED--------------------------------I------------------------------------------------------------------IG-ASS-----------------------------------------------------------------------------------------------DCST----------------------CF-VS----------------QSG------TSQAAAHVA----G---------------------------I------------------AA-M----ML----S-------AEPELT-----------------------------------------------------------------LAE--------------L---------------------RQRL-------IHFSAKDVINEAWFPEDQRVLTPNLVAALPPS---TH-----------------------------------------------------GAGWQLFCRTVWSAHSGPTRMATAVARCAPDEELLSCSSFS-RSGKR 525
 526 FAQSIPW-------NLERIIPAWHQT--------------E--ED-------RSP-DGSS--------------------------Q-V--EV--------------Y--------------------LLD---------------------------T--------------SIQG-A------H-------------R---------E--------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RVTITDFNSVPEEDGTRFH----------RQAS-----------------------------------------------------------------------------------------K---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-L-----------------------AGVVS----GRD-----------------------------------------------------------------------AGV--AKG-T--SLHSL---RV---LNCQ----------G-KG--T------------VSG-------------------------------------T--------LIG--------------L-----------EF---IR--------------KSQLIQP-----S------G------------P--LV-----------------------------------------VLLPLA---------GG----Y--------------------SR--------------------------ILNA-----ACRHLA--------R-T----GV-----V--------------------------------------------------------------------------------------L---------------VAAAG-NF--------RD---------D----A---CLYS---------------------------------------------------------------------------------------------------------------------------------------P-ASAP-E---------------------------V---IT---VG--A------------------------------T-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------QD-------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVTLG------TLG-----T--N--------F-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------G-----------------KD--------------------------------I------------------------------------------------------------------IG-ASS-----------------------------------------------------------------------------------------------DCST----------------------CF-MS----------------QSG------TSQAAAHVA----G---------------------------I------------------VA-R----ML----S-------REPTLT-----------------------------------------------------------------LAE--------------L---------------------RQRL-------IHFSTKDVINMAWFPEDQQVLTPNLVATLPPS---TH-----------------------------------------------------ETGGQLLCRTVWSAHSGPTRTATATARCAPEEELLSCSSFS-RSGRR 526
 527 --------------------------------------------------------DGAG--------------------------P-V--EV--------------Y--------------------LLD---------------------------T--------------SMHS-G------H-------------R---------E--------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RVTVTDFENVPEEDETRFH----------RQAR-----------------------------------------------------------------------------------------RAALC---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHS-------TY-L-----------------------AGVVS----SHD-----------------------------------------------------------------------AGV--AKG-T-----SL---RV---LNCQ----------G-KG--T------------VSG-------------------------------------V--------LAG--------------E-----------EL---CL--------------DSLLVRP-----T------G------------R--LV-----------------------------------------MLLPLA---------GG----Y--------------------SW--------------------------AFNA-----ACQRLV--------R-T----GA-----V--------------------------------------------------------------------------------------L---------------VAAAG-NF--------CD---------D----A---CLSS---------------------------------------------------------------------------------------------------------------------------------------P-ASAP-D---------------------------ASLGSR---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------QD-------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVT-G------VLR-----T--N--------F-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------E-----------------DD--------------------------------I------------------------------------------------------------------IG-TSS-----------------------------------------------------------------------------------------------DCST----------------------CY-TS----------------QSG------TSQAAAHVA----G---------------------------I------------------VA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 527
 528 FAQSTPW-------NLERIMPVRPQE--------------D--EY-------HPP-DGAG--------------------------P-V--EV--------------Y--------------------LLD---------------------------T--------------SMHS-G------H-------------R---------E--------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EG-----RVTVTDFENVPEEDETRFH----------RQAD-----------------------------------------------------------------------------------------K---C---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------SHS-------TY-L-----------------------AGVVS----SHD-----------------------------------------------------------------------AGV--AKG-T-----SL---RV---LNCQ----------G-KG--T------------VSG-------------------------------------V--------LAG--------------L-----------EF---IW--------------KSQWAXP-----T------G------------R--LV-----------------------------------------MLLPLA---------GG----Y--------------------SW--------------------------AFNA-----ACQRLV--------R-T----GA-----V--------------------------------------------------------------------------------------L---------------VAAAG-NF--------CD---------D----A---CLSS---------------------------------------------------------------------------------------------------------------------------------------P-ASAP-D---------------------------V---IT---VG--A------------------------------T-----------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-------------------------------------------------------------------------------------QD-------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVTXG------VLR-----T--N--------F-G---R--------------------CV------------------------------------------------D-----L------F-----------------A-----P-------------E-----------------DD--------------------------------I------------------------------------------------------------------IG-TSS-----------------------------------------------------------------------------------------------DCST----------------------CY-TS----------------QSG------TSQAAAHVA----E---------------------------M------------------CS-R----PL----G-------R----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 528
 529 ----------------------------------------------------------GQ--------------------------DQV--IT-----------------------------------IGD---------------------------T--------------GVDY-L------H-------------P---------F--------------------------------FVDPNFDV--STLVNKT-NKYHRKIIRIEAFSDYS-DYAN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGVAL----GEPYD-------------------------------------------------------------STAYSFQYKGV--APK-A--KLYML---DM-----------------GSANI-NRDLSAYLDYQVVLSN-------------------------------------M--------KT---------------F-----------NS------------------------------------------------------GI-----------------------------------------FSNSWSYNE--YSQ--------------------------------------------------------EITQNFDSMAYNNS----------------DI-----L--------------------------------------------------------------------------------------F---------------VFSAG-NVYGP--MTILS-------------------------------------------------------------------------------------------------------------------------------------------------------------PGDTKN-----------------------------V---LT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MT--------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SICSDLL--------------------------------------------IEYDIFLHPYSS-----------Q-GPCFN----------------------------------------------------------------------GIFKPDV------A-----------------A-----P-------------G-----------------YN--------------------------------I------------------------------------------------------------------LS---------------------------------------------------------------------------------------------------------------------------ARALSTSNGI--------DGLSEKTG------TSMATPLVS----G---------------------------S------------------AALV--------------------------------------------------------------------------------------------------------------------------------RQWFMQGKYPSIKK--------PSSYLIRAVIINS----------------------------------------------------------------------------------------------------------------- 529
 530 ----------------------------------------DDMKGYVINRDLHSRGIEGQ--------------------------NQI--IT-----------------------------------IGD---------------------------T--------------GVDY-N------H-------------Q---------F--------------------------------FLDPTQDI--HTLVNKT-NLNHRKIVRIEAFRDYS-DYYD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIAL----GEPYN-------------------------------------------------------------SSLYSYQYKGV--APK-A--KLYML---DM-----------------GFANI-SRDLSALPDFNLVFSH-------------------------------------M--------KE---------------L-----------NS------------------------------------------------------GI-----------------------------------------FSNSWGYNL--YSR--------------------------------------------------------EITQYFDSMAYDNP----------------DI-----L--------------------------------------------------------------------------------------F---------------IFSAG-NVFGP--MTIIT-------------------------------------------------------------------------------------------------------------------------------------------------------------PGDSKN-----------------------------I---FT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MT--------SKPSSNL-----------FEYPVYRAYYITDGS-----------GIKVPLVGTPNYSLPYFPLDEKLKTYIDIPLTVGSPSEGKAYFTTDDPCSELSKALAAKASIFLYTS---------------EL-------------------------CPLDTPQNIVCARIEAQFASIVESWKKITICSDIL--------------------------------------------VEYEVFSHPSSS-----------Q-GPGYN----------------------------------------------------------------------GIFKPDI------S-----------------A-----P-------------G-----------------YH--------------------------------I------------------------------------------------------------------FS---------------------------------------------------------------------------------------------------------------------------AKALSTGGTI--------DSLSQKTG------TSMSAPLIA----G---------------------------V------------------AALV--------------------------------------------------------------------------------------------------------------------------------RQYFMDGHYKGITK--------PSSSLIKATILNSAIQI------------------------------------------------------------------------------------------------------------- 530
 531 -------------------------------------------------------NLTGQ--------------------------NQV--IT-----------------------------------LVD---------------------------T--------------GIDM-E------S-------------P---------Y--------------------------------FKDENND----PPFNTT-NFNHRKVIRYEILADNK-DRNG--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIIS----GDA---------------------------------------------------------------ESLPYSLYNGI--APK-S--KLYFI---DI-----------------GKKQF-LDDADVDYDINDVVKR-------------------------------------M--------KE---------------L-----------NS------------------------------------------------------HI-----------------------------------------FSYSWGFPI--DFS--------------------------------------------------------DIRSTYDYIAEKNP----------------EI-----L--------------------------------------------------------------------------------------F---------------VFAGG-NSGNK--FSIYQ-------------------------------------------------------------------------------------------------------------------------------------------------------------PSGSKN-----------------------------V---VS---VA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GC--------SHPSSGN-----------IENLMMRDIYILKND-----------KKRVNVTQTYWSPDFY------------------------SKFRFNNQSFFRNQSFSTKMNPKTFFF---------------ME-------------------------YDNTTCQKIKNFNENQSLAIFIKSDKKIECPSSKIPIFLTKEKLKGN-------------------FNCSIIYEPKTSEISYSEF----SS-----------K-GPNDV----------------------------------------------------------------------GILKPDL------V-----------------A-----P-------------S-----------------SY--------------------------------I------------------------------------------------------------------IS---------------------------------------------------------------------------------------------------------------------------AKA----NSK--------EIVGARTG------TSMAAPFIA----G---------------------------S------------------AALI--------------------------------------------------------------------------------------------------------------------------------RQ-------------------------------------------------------------------------------------------------------------------------------------------------- 531
 532 -------------------------------------------------WSLRSTNLTGK--------------------------GEI--IA-----------------------------------LAD---------------------------S--------------GIDY-R------H-------------P---------M--------------------------------LNDSSRQ-----LINNTLDLNQRKIVYYDSWKDFY-DYIP--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------AGIIA----GKS-E-------------------------------------------------------------CGNILPLYDGI--APE-S--KLYFL---DM-----------------AKGD--NKMLFDDFDKDKFVQS-------------------------------------L--------KD---------------L-----------NI------------------------------------------------------GI-----------------------------------------SSNSWGSNEIDYTS--------------------------------------------------------TMTDIYDNLAYNNP----------------DI-----L--------------------------------------------------------------------------------------F---------------VFAAG-NSEKS--WTIDS-------------------------------------------------------------------------------------------------------------------------------------------------------------PSSGKN-----------------------------I---FC---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATDGTPGQMMGEASTPQ-----------IEI-----------S-----------GTKIDLLQSSWSTNLFNQLNKEE-----------------PLFNVAKPVYVTSNDNTCDSIKQILEN---------------EQ-------------------------TKILILKSLPDCNKMSKTVLATLSDDDFQLISQSS----------------------------------SANFTMKLSDFSYEKA--NFAS-----------A-GPAYS----------------------------------------------------------------------GILKPDI------S-----------------A-----P-------------G----------------------------------------------------------------------------------------------------------------------VI---------------------------------------------------------------------------------------------------------------------------TGALSYGNSETAERKCDFSSLSQFTG------TSESTPIIS----G---------------------------F------------------SSLL--------------------------------------------------------------------------------------------------------------------------------RE-------------------------------------------------------------------------------------------------------------------------------------------------- 532
 533 -------------------------------------------------------GITGK--------------------------GQI--IN-----------------------------------VVD---------------------------S--------------GVDR-M------H-------------C---------L--------------------------------FYDPDHEV----PVNKT-DFSHRKIVRIDDWKDSL-DHSD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGISL----GNAYK-------------------------------------------------------------QKSGMSLYNGV--APD-A--KLFMT---DL-----------------GDAAI-RDDVSADYDLSLTSQR-------------------------------------Q--------LK---------------M-----------GS------------------------------------------------------YI-----------------------------------------SSNSWGFFP--NIH--------------------------------------------------------IITVLHDYEAYNNP----------------NI-----T--------------------------------------------------------------------------------------F---------------VFAAG-NRGRD--LTINS-------------------------------------------------------------------------------------------------------------------------------------------------------------AGDSKL-----------------------------V---LT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NA--------VSPSIYT-----------VE-DSRSIVMVN-EN-----------GDKVQLSENFGSRYWDLQRSEDSLQIID-----------------------KNIVQYEAGKQYNDNI---------------VL-------------------------ISCSDLEKLEQNSTNGILAFITSQSCNNNFAKIASFNAKDSFKTISG-------------------FKKGTIFFEQVNYNSPRIG--GSSS-----------R-GPTRR----------------------------------------------------------------------NILKPDV------V-----------------A-----P-------------G-----------------QP--------------------------------I------------------------------------------------------------------LS---------------------------------------------------------------------------------------------------------------------------AKAGSPKRTS--PGSCSASEIISKQG------TSMAAPTIS----G---------------------------L------------------SALI--------------------------------------------------------------------------------------------------------------------------------M--------------------------------------------------------------------------------------------------------------------------------------------------- 533
 534 -----------------------------------------------------NFGLDGT--------------------------NQI--IN-----------------------------------IVD---------------------------S--------------GIDE-Y------H-------------C---------F--------------------------------FYDSKYTI----SINST-NLKHRKVVRIDEWVDTQ-DAED--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------GASIA----GYPDC-------------------------------------------------------------EDCGIKLYSGV--AKG-A--KLYVT---DI-----------------GISSI-KSDVSGNYDLDQTTQT-------------------------------------M--------KQ---------------L-----------DS------------------------------------------------------GV-----------------------------------------SCNSWGYSA--EVG--------------------------------------------------------QIEYSYNLEAEKNP----------------EI-----A--------------------------------------------------------------------------------------F---------------VFAAG-NSRDP--LTVTV-------------------------------------------------------------------------------------------------------------------------------------------------------------PSISKN-----------------------------V---IT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LS--------SNAPSYS-----------MEINEGNISLSD-PQ-----------GLRIPLTQSSNTDYFKMTAGTPMTWLSN-----------------------LSVVDYADDADFQGKI---------------VK-------------------------TS-NNLDDISNSLERGAKAVISVTKNELKTQKSPVFFSSEDFNV-----------------------DQGSILLESYSNKEFEVS--YIES-----------R-GPASN----------------------------------------------------------------------GLLKPDV------V-----------------A-----P-------------G-----------------HP--------------------------------L------------------------------------------------------------------KS---------------------------------------------------------------------------------------------------------------------------ARAGDPENQT--RRECTIDTISRKQG------TSMATPLIA----G---------------------------L------------------CGII--------------------------------------------------------------------------------------------------------------------------------RQYFVEGWYKDSKK--------NSAEKVVPSSALMKNVLVAAAYPIGSITPN------------------------------------------------------------------------------------------------ 534
 535 --------------------------------------------------------LNGK--------------------------GQV--IS-----------------------------------VFD---------------------------T--------------GVDY-L------H-------------P---------F--------------------------------FYDPNVKP----PVGTA-NPAHRKILQIVPCADSK-DVLH--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGTAL----GEAYC------------------------------------------------------------GPECGLSLYNGV--ASK-S--KLIMY---DL-----------------GFFHD-GNAMNGDFSLENSSID-------------------------------------I--------QE---------------L-----------GS------------------------------------------------------YI-----------------------------------------SSNSWGVDV--DCD--------------------------------------------------------EVTWGYDVMSYFHP----------------HL-----L--------------------------------------------------------------------------------------F---------------VFAAG-NSGAA--HDLSC-------------------------------------------------------------------------------------------------------------------------------------------------------------PSDSKS-----------------------------V---LS---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SVDRLKLSYIHDYSAPI-----------YAEHNSSQISVNQIS-----------NSKNILSSSINDGAKYRIYEREIAPVTDCKDKVVM--------------------------------------------------------------------------ISRNDCETLQKAVDGGAAAVIMSGGNSCSVSLSNV------------------IGVYTSEDSFNVIKSWGRVTLTKRSVRSGNQVKASFSS-----------Y-GPSFY----------------------------------------------------------------------SLTKPDI------L-----------------V-----P-------------G-----------------QT--------------------------------V------------------------------------------------------------------YS---------------------------------------------------------------------------------------------------------------------------SDGAVHYSEN--PTAATESSLVTKSG------TSMSTPAAA----G---------------------------M------------------AAII--------------------------------------------------------------------------------------------------------------------------------RQFFVDKFYPYFEQRDDGETFNPTSYFVRACFITCSQPIQGASYLTPDTASGYGTPVLN----------------------------------------------------------------------------------------- 535
 536 --------------------------------------------SYEIKRKFNDLGLTGK--------------------------NQI--VN-----------------------------------LVD---------------------------T--------------GIDE-F------H-------------P---------F--------------------------------FYDDRMRAPRSDANNLNFDLNHRKIVSIYNASDYK-DDKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGNIL----GKADC-------------------------------------------------------------ETCPINKYRGM--APD-A--KLFVV---DV-----------------SKVG--EQGLSIAFNPITMAKN-------------------------------------L--------SEK--------------V-----------DS------------------------------------------------------HI-----------------------------------------SSNSWGSST--PIP--------------------------------------------------------LFSYLYDLAASTVR----------------DF-----L--------------------------------------------------------------------------------------Y---------------VFAAG-NDGQEGVMTISS-------------------------------------------------------------------------------------------------------------------------------------------------------------PSDAKN-----------------------------V---LS---VT------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AS--------TMPEAAQKKLYQLMNLSFVSSDGYVSVSVNKTG--------------------DNTLLLQNELDDPSWKWSNIKLAEMSDFENLPETEAKGRVILLDSIKFTGTNRSYVDICDAALRFDRLGAVGVVYNGTKANNFCHHLGISFDIPVFFTLHGGFDDLMRLSENDTTVSLKKVLNEKSMLKMESAFF------------------------------------------------------SS-----------M-GPTLK----------------------------------------------------------------------GQNKPDV------I-----------------L-----P-------------G-----------------FF--------------------------------T------------------------------------------------------------------VS---------------------------------------------------------------------------------------------------------------------------ADSGDPEIEE----KRSLKSLITMSG------TSMATPLMA----G---------------------------T------------------ATLI--------------------------------------------------------------------------------------------------------------------------------RDFFSNGYYRDLKE--------DNSSSVKP---------------------------------------------------------------------------------------------------------------------- 536
 537 -------------------------QFMNRWSHSYLQTRDRRVYYNKYAEGRRIEGLDGR--------------------------NTI--VT-----------------------------------LID---------------------------T--------------GVNS-N------H-------------L---------F--------------------------------FKDKNRTF----PYNKT-DLEHRKIVRYDSTIDSV-DYLN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------AGIIA----GYAED-------------------------------------------------------------EDSGLNLYRGG--AYK-S--KLFVV---DI-----------------NKDSSAKEVLIPLNLIFSAANE-------------------------------------S--------KK---------------L-----------KS------------------------------------------------------HI-----------------------------------------TSCSWGSKD--SNN--------------------------------------------------------ELTWIMDQLSYEME----------------DI-----L--------------------------------------------------------------------------------------Y---------------VFAAG-NEGKF--RKVGS-------------------------------------------------------------------------------------------------------------------------------------------------------------PADSKN-----------------------------V---LT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SA--------NPHAAIT-----------TESERYTFIKLKDQNIESVSSNLFNFMKKVTNLKSYENISMTNDTDNASGKVFLMKEKSDKKYTAKGRGKITHDRKIDPELDYIKDTDYIIRY---------------IEDATVPDKNDEFYDLVTNINSKRGRKMRIKKYLDLLEEEDEEEKYIQHSTKSDVPIPNDVLAVVTDNPNYKSDKYPVLLVTDADLEKLISNMNENISLRFEYEDNKGTELS--PFTT-----------F-GPSPK----------------------------------------------------------------------GTIKPDV------Y-----------------G-----I-------------G-----------------ER--------------------------------V------------------------------------------------------------------IS---------------------------------------------------------------------------------------------------------------------------AGTADE------------TSLKQMTG------TSMAAPTIS----A---------------------------L------------------LALV--------------------------------------------------------------------------------------------------------------------------------QQYLIEDGW------------------------------------------------------------------------------------------------------------------------------------------- 537
 538 --------------------------------------------------------LTGK--------------------------GQI--VH-----------------------------------VAD---------------------------S--------------GIDYNH------HFFYDPDHPKLEFNK---------T--------------------------------MPNHRKIYRYDTIADTSDYEG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-V-----------------------CGILA----GKSIN-------------------------------------------------------------NQSFASQYDGI--APD-A----------KI-----------------------MILDTIIGGISNKSSK----------------------------------------------IKN--------------IELDFDIEQRYKEI-------------------------------------------------ANERVGI-----------------------------------------ASNSFGET-----------------------------------------------------------------------IYTDLTYIYDIVTYQHK----DI-----L--------------------------------------------------------------------------------------I---------------VKSAG-NRLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------P--------------------------------------LT---VGTFGDSKNVFTVGNVYKPYTWRIDQGNVTYQFVLK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGEKINSTF-----SNVSDANLVDVQS--------------------------NLLDLKNMDVSDGPMVGKLWAVIDNNEDICTIAQSARDKRAFGIVYLDEKDPCNENYVAQFAVKTKEELQKINNSTRVTINQLSTDKPLDINLYKVSSQGPGYSGVTKPDIVAPGAFIYSA---------------------------------------------------------------------------------------------------YS--------------------------------------------------------------------------------------------------------------------------------RGNNSVFKEDYSMSTLITKSG------TSMSCPLMA----G---------------------------S------------------AALVRQYFMEGWFNEKKGKGFVPTASLL--------------------------------------------------------------------------------------------------------KAVI-------MNS----------------------------------------------------------------------------------------------------GKPVNKSLFKDNAVGYGLPNL------------- 538
 539 ---------------------------------------------------------NGS--------------------------GEV--VH-----------------------------------VAD---------------------------S--------------GLDV-D------H-----------------------CFFRDSKRSLTYNKVDRKHRKLLVYWISRHGDGFDSIG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSIA----GSLED------------------------------------------------------------VTWHPLANFSGV--APA-C--KLAFT---DAERQTSSD----------G-EGPFVLDDIPSSIYLKPYEE----------------------------------------------VGA----------------------------------------------------------------------------------RL-----------------------------------------HSHSWGTQDFSY-------------------------------------------------------------------TIDAHELDDFIYRHPDA-----------F--------------------------------------------------------------------------------------F---------------SWAAG-NDGEQERFGLIAS------------------------------------------------------------------------------------------------------------------------------------------------------------PASAKN-----------------------------C---LS---VG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATF-----APVDNAHVLSFSARGPCKD----------------------------------------------------------------------GRLKPDV------V-----------------L-----P-------------G---------------------------------------------------L------------------------------------------------------------------LHSAQG----------------------------------------------------------------------------------------------------------------------------QVGNDCSQTVQEKLATLTKMG------TSMAAPVAA----G---------------------------L------------------AAL------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 539
 540 ----------------------------------------------GVPLAHAQG-IRGA--------------------------G-V--ML--------------G--------------------ILD---------------------------T--------------GVDA-D------H-------------P---------E---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HAARVIQFRYVSLFPNSPHNPARDIRGFDPD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGIAA----GVH-----------------------------------------------------------------------HGV--APE-V--DLYVA---SV-----------------------I------------ESE-------------------------------------TIRTSLGRVAAG--------------MEWLLHQFSRPENSTRPAV--------------------------------------------------------------------------------------------VNLSLGFPLMPPPGISEADY-----------------------------------------------------------NLNLRALQTMIRRLLDS----NV-----L--------------------------------------------------------------------------------------P---------------VVAAG-NS--------GPDTVGY--------------------------------------------------------------------------------------------------------------------------------------------------------PAAFPE-----------------------------S---LA---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDFERNVATF-----SASG--------TVGRR------------------------------------------------------------------------------V------------------------V-----P--------DIMGYG---------------------------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NVYSSTERRCNNQAFYERMSG------TSMAAPYVA----G---------------------------I------------------AALY----------------RCRAPDLT----------------------------------------------------------------------------------A------------------LEVRDLI-------LSNA------------------------------------------------------------------------------------------------------------------------------------- 540
 541 ---------------------------------------QRINNMYQTDRTITKMGITGK--------------------------KQV--VT-----------------------------------IID---------------------------T--------------VLDV-N------H-------------T---------F--------------------------------FYDPYHKV----S-SSM-NSQHRKVVKYFSLFDNH-DAIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------AGIVA----GKALE-------------------------------------------------------------SDSMQSLYSGV--AEG-A--KLHVI---DI-----------------GND---KNEITVTPNPNTFQEN-------------------------------------M--------KD---------------T-----------TS------------------------------------------------------KI-----------------------------------------QTSSWGFDN--N-N--------------------------------------------------------LLRNSFDEIAFNNQ----------------DT-----V--------------------------------------------------------------------------------------Y---------------IASAG-NRKSA--MSVFP-------------------------------------------------------------------------------------------------------------------------------------------------------------PGNSKN-----------------------------F---IT---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AL--------ADSTVSS-----------FT-DTADIYVTNGET-----------KIKVLDPQKFMSKY-------------------------------------------------------------------------------------------------------------------------------------SADF-----------------------------------------------SS-----------W-GPTEE----------------------------------------------------------------------GILKPEV------I-----------------A-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------VS---------------------------------------------------------------------------------------------------------------------------AKSLGKHDYH--PL-INEENLVKQEG------TSMAAPMVA----G---------------------------L------------------AALI--------------------------------------------------------------------------------------------------------------------------------KD-------------------------------------------------------------------------------------------------------------------------------------------------- 541
 542 -----------------------------------NEVDNRTIWE-------K-G-ITGA--------------------------G-Q--IV--------------G--------------------IAD---------------------------S--------------GVDY-D------M-------------P---------W--------------------------------FAD--------------PN----GALP--G--------PG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIVGYD-AT--LGDNH-DVAD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------AGTIC----GDR---------------------------------GP-----------------GMPG------N---------GI--APG-A--RIHVQ---DL-VG-TDG----------T-LT--G------------SLE---------------------------------------------------------------L-----------ET----V--------------LKKAY-D-----S------G----------A----RI-----------------------------------------FNGSWGVDS------GN-YDAL--------------------AA-----------------------------------ALDDFS-------WRHK----DF-----L--------------------------------------------------------------------------------------A---------------VFANG-N------------GGPAE-----------QTATS---------------------------------------------------------------------------------------------------------------------------------------P-AIAK-N---------------------------A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSVVATGNG-----------------------------------------------------------------------TDA--------------------------------------AT---------VSAE------------S--S--------V-GQA-PDGRANP----------------------------------------------------------------S-----V------G-----------------A-----P-------------G-----------------QG--------------------------------V------------------------------------------------------------------VS-ARS---------------------------------------------------------------------------------------------------------------DG-----------LLGSGN----SGTM--A-MSG------TSVAAAVTS----G---------------------------A------------------AA-LIRQYFT-------------------------------------------------------------------------------DGFFPTGSPVATNKLQPSAALL---------------------KAVL-------VNSAE-------------------------------------------------------------------------------------------------------------------------ALLSDDPGDSC 542
 543 --------------------------------------------------------LDGS--------------------------G-Q--VI--------------T--------------------ITD---------------------------S--------------GVDI-Y------H-------------P---------F--------------------------------FYD--------------PN----ISVPI-NTSI-----LR-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIVRFD-----SLHNLTDFKR--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-M-----------------------AATIA----G-----------------------------------SS------------NSPDCSIDSF-----S---------GL--APG-S--KLYVV---GLSDK-DGN----------I-SF--D------------GYD---------------------------------------------------------------M-----------NK----V--------------YQNAK-K-----L------H----------S----YI-----------------------------------------GANSWGMTD---------YQSL-------------V------TE-----------------------------------AYDLMA-------YNNP----DF-----L--------------------------------------------------------------------------------------T---------------IFSVG-NS--------NCYN----------------CLSS---------------------------------------------------------------------------------------------------------------------------------------P-SDAK-N---------------------------I---LS---VG--A------------------------------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMPSTAQIEQYLKRVYTF------------------------VSRSLDITLKFYQWSADPWKLLLESPPVKIVNSPLFMQDNPNLQKIKSNESKIIILKEPITCESFTRNATAYLIPVDQKLFCKNIPVPVFGYSMNEENDIL---------------------------------SMKRVSLRI---NVIPSKKNIKP-LSS-----N--S--------N-GPT-VTGIFKP----------------------------------------------------------------E-----L------L-----------------A-----P-------------G-----------------EG--------------------------------V------------------------------------------------------------------IS-AAA--------------------------------------------------------------------------------------------------------------GDPFDKTIR-----KC------NASSLI--K-KSG------TSPAAASIA----G---------------------------A------------------AA-IIRQYFS-------------------------------------------------------------------------------DGWYP------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 543
 544 --------------------------------------------S-------K-G-LRGS--------------------------G-E--II--------------G--------------------CAD---------------------------T--------------GVDY-D------S-------------C---------F--------------------------------FRD--------------STEQVKTCQGP-GALENC-VNMN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIVSYR-FFTNSSTDVSDKVG--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSIL----GNSLS-------------------------------NS------------------TGPY-----N---------GA--APD-A--KLSFD---DVSND-ISE----------A-FF--L------------PDD---------------------------------------------------------------L-----------NT---QL--------------FPHSY-A-----L------G----------A----KL-----------------------------------------HSDSWGSDTPQ-------YTSS--------------------SK-----------------------------------EMDQFM-------FDHD----DF-----L--------------------------------------------------------------------------------------I---------------LVAAG-NT--------GPGA---------------GTIGS---------------------------------------------------------------------------------------------------------------------------------------P-ATGK-N---------------------------I---LA---VG--A------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GNTLA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYVE----------------TYL-ANF-----S--S--------R-GPT-PDRRFKP----------------------------------------------------------------D-----I------V-----------------C-----P-------------G-----------------DS--------------------------------I------------------------------------------------------------------LS-ARS---------------------------------------------------------------------------------------------------------------DGNLSSF------QC---------SIM--V-MSG------TSMATPICA----G---------------------------A------------------AA-LVRQYFR-------------------------------------------------------------------------------EGFLSSGVRNTSNGIAPSASLI---------------------KAVM-------IHAGQ----------PMWFLEES-TWKFPASLPHFSQGFGRVVLDSVLYLGPETPFKLKVWDREVVQNQ-------------------------------------------------------------------- 544
 545 -------------------------------------GTQNKLWS-------Q-G-LLGS--------------------------G-E--IV--------------G--------------------CAD---------------------------T--------------GVDY-D------S-------------C---------F--------------------------------FQD--------------PNQQVKTCQGL-GAPANC-VNMN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIVSYR-YF--ASTNVGDTSY--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------VGSIL----GNSLS-------------------------------SD-----------------YTVSY-----N---------GG--APE-A--KLSFD---DISSD--GS----------S-LW--L------------PDD---------------------------------------------------------------L-----------NT---DL--------------FPHAF-A-----V------G----------A----NL-----------------------------------------HSNSWGSSTSA-------YTST--------------------AQ-----------------------------------EMDQFI-------FDHD----DF-----L--------------------------------------------------------------------------------------I---------------LVAAG-NS--------GPGA---------------GTIGS---------------------------------------------------------------------------------------------------------------------------------------P-ATAK-N---------------------------I---LA---VG--A------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANTLA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------AYQDYDGYT---GTAHDKQRTGL-VDF-----S--S--------R-GPT-PDGRFKP----------------------------------------------------------------D-----I------V-----------------C-----P-------------G-----------------ES--------------------------------I------------------------------------------------------------------RS-AYS---------------------------------------------------------------------------------------------------------------DGTLTSF------QC---------SIA--E-MSG------TSMATPTCA----G---------------------------A------------------SA-LVRQYF------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 545
 546 ------------------------------------------IWN-------R-G-INGS--------------------------S-Q--II--------------G--------------------IAD---------------------------T--------------GIDY-D------H-------------C---------F--------------------------------FND--------------PFETVAKCTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KIVTYR-KF--SSTDYQDYYG--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSVA----GNAYD-------------------------------AD------------PTEMNYAGAY-----N---------GM--APG-A--KIAFD---DVGDS-KGA----------L-PG--I------------PDD---------------------------------------------------------------L-----------NT---GL--------------FPHSY-H-----A------G----------A----RL-----------------------------------------HSNSWGAKFAG-------YESM--------------------AM-----------------------------------EIDEFT-------HDHD----DF-----L--------------------------------------------------------------------------------------V---------------LVAAG-ND--------GPHP---------------YSIGT---------------------------------------------------------------------------------------------------------------------------------------P-ATAK-N---------------------------I---LA---VG--A------------------------------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DNSLK---------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHSH----------------EHL-VYF-----S--S--------W-GPT-YDFRIKP----------------------------------------------------------------D-----V------L-----------------C-----P-------------G-----------------YR--------------------------------I------------------------------------------------------------------HS-SFS---------------------------------------------------------------------------------------------------------------DGDPTSF------QCGAYANSAGGALL--E-MSG------TSMATPLCA----G---------------------------S------------------AA-LVRDYFK-------------------------------------------------------------------------------GGHHAGG--DASKGFNASAALV---------------------KATM-------IHSAQ----------PAMVQSASGAWEFPSSVPNIQTGYGRIDLSK------------------------------------------------------------------------------------------- 546
 547 --------------------------------------------------------ITGT--------------------------G-Q--IL--------------G--------------------IAD---------------------------T--------------GIDM-N------L-------------C---------F--------------------------------FYD--------------AD----HPAPY-NTVN-----RN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKVISYRGRA--GQGNTWDE-E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------TGSLS----AKALT-------------------------------SP------------Q------SDF-----N---------GM--APD-A--KIVFD---DIFQN-GD-------------LT--P------------PDD---------------------------------------------------------------L-----------EH---DL--------------FPEPY-S-----L------G----------A----AV-----------------------------------------RSESWGGDSIF-------YTTS--------------------AK-----------------------------------EIDSFS-------YSH---------------------------------------------------------------------------------------------------------------------RAG-ND--------GDLG---L-----------FTIGS---------------------------------------------------------------------------------------------------------------------------------------P-ATAK-N---------------------------I---LC---VG--A------------------------------Q-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSTMESLMLETSDTTFITLSAENDELEKQKIMAKWASFGNKGEISG-------------SVVIASQIEACQALSS---------------TANGKIVLVARGTCAFTTKASNVQSAGGIAMIVYDNVYG-----------TPVIMGGTDATITIRCVSISRYDGETALSMLQSANGAYSILASTS---GSGPDLWQQNL-AYF-----S--G--------K-GPT-GDGRLKP----------------------------------------------------------------D-----I------I-----------------T-----P-------------G-----------------AD--------------------------------I------------------------------------------------------------------WS-AKS---------------------------------------------------------------------------------------------------------------GGLSTPAG-----QCG-GVPPNAGACV--TGMGG------TSMAAPVAA----G---------------------------G------------------VA-LIRQYFM-------------------------------------------------------------------------------DGWYPTGVAVA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 547
 548 --------------------ITAKPEYKVMNDVARGIVKADVAQS-------SYG-LYGQ--------------------------G-Q--IV--------------A--------------------VAD---------------------------T--------------GLDT-GRNDSSMH-------------E---------A--------------------------------FR-------------------------------------G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KITALYAL-----GRTNNANDTN--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSVL----GNGST-------------------------------N----------------------------K---------GM--APQ-A--NLVFQ---SIMDSGGGL----------GGL----------------PSN---------------------------------------------------------------L-----------QT----L--------------FSQAY-S-----A------G----------A----RI-----------------------------------------HTNSWGAAVNGA------YTTD--------------------SR-----------------------------------NVDDYV--------RKN----DM-----T--------------------------------------------------------------------------------------I---------------LFAAG-NE--------GPNG---------------GTISA---------------------------------------------------------------------------------------------------------------------------------------P-GTAK-N---------------------------A---IT---VG--A------------------------------T-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ENLRPSFGSY--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADNINHV-AQF-----S--S--------R-GPT-KDGRIKP----------------------------------------------------------------D-----V------M-----------------A-----P-------------G-----------------TF--------------------------------I------------------------------------------------------------------LS-ARS--------------------------------------------------------------------------------------------------------------SLAPDSSFWANHDSKYAY--------------MGG------TSMATPIVA----G---------------------------N------------------VA-QLREHF-----------------------------------------------------------------------------------------VKNRGITPKPSLL---------------------KAAL-------IAGAA---------------------DIGLGYPNGNQGWGRVTLDKSLNVAYVNESSSLSTS--------------------------------------------------------------------------- 548
 549 -------------------------GMTQAQYDDPMAASNRPFWD-------A-G-LDGE--------------------------G-E--VV--------------G--------------------VGD---------------------------T--------------GLDL-D------H-------------C---------F--------------------------------YAD--------------PRFSNYAALLK-GAPRRF-RTPA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKVVQYV-VF--KGAKFGDDGD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGSVA----GAA---------------------------------MP------------VDGN-GTSDFVLQFGT---------GG--APR-A--RLTFN---DI-GG-TGG----------N-LI--N------------IDN---------------------------------------------------------------V-----------DE----L--------------YLPFHKN-----V------G----------A----AI-----------------------------------------TSDSWGPMW------SN-YDGL--------------------AR-----------------------------------RFDSFL-------WRNP----DM-----T--------------------------------------------------------------------------------------S---------------FIAAG-NS--------GDDNTRVG-----------GTVDS---------------------------------------------------------------------------------------------------------------------------------------P-ANAK-N---------------------------V---VG---VG--V------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YKYPAGVSFATLLKIRGYQPSSAGDVRLFDLALQPAETGGLPYLSSV---------------VSATSETLVGVSTPIDACEPLYPEALAHVPGRVVLVSYSDRCDVDTRARNLQDAGAAAMMMIHHSPNMEYTESPPLSNSDGPAIRIPVSSIPQVMGGWLVGNVTAGVELRL---TWQDYPQ---------SVGDVVR-W-------S--G--------Y-GPT-RDGRIKP----------------------------------------------------------------D-----V------I-----------------A-----P-------------G-----------------YD--------------------------------I------------------------------------------------------------------VS-AKA--------------------------------------------------------------------------------------------------------------VDG----------ITGGQCN----DETQ--E-MSG------TSMATPLAA----G---------------------------S------------------AA-LLRQYLR------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 549
 550 ---------------------------------------------------------------------------------------------------------------------------------AD---------------------------T--------------GLDL-N------H-------------C---------Q--------------------------------FRE--------------DDGDNIEASDW-DDPVTD---LD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRKVVQYI-----DFVDDFDEAD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGSIC----GAQSG-------------------------------ED------------AGDDDA---------D---------GM--AFQ-G--KLAVF---DFGDS-DNF----------NALT--T------------PDE---------------------------------------------------------------I-----------DS---VI--------------LEPAY-D-----G------G----------A----RV-----------------------------------------HSNSWD-TVSTE------YTAL--------------------SN-----------------------------------EVDEFV-------YTHQ----NM-----L--------------------------------------------------------------------------------------V---------------VFAAG-NC--------GDTSTDDLIDNCSVLDDDEGTVLS---------------------------------------------------------------------------------------------------------------------------------------P-AQGK-N---------------------------V---VA---VG--S------------------------------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------E----SGGVT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GKDMDTV-SYF-----S--S--------K-GPT-IDGRIKP----------------------------------------------------------------D-----V------V-----------------A-----P-------------G-----------------DP--------------------------------T------------------------------------------------------------------WS-A------------------------------------------------------------------------------------------------------------------AADTT---GETCEFGS--------------QTG------TSMSTPIVA----G---------------------------N------------------GA-MARQYF-------------------------------------------------------------------------------------------------------------------------------------------------------------------------REGW-------------------------------------------------------------------------------------------------- 550
 551 -------------------FQTANRLSPKAIFGTKDTLVNNDRID-------I-P-LRGK--------------------------G-Q--IL--------------S--------------------IAD---------------------------T--------------GLDG-S------H-------------C---------F--------------------------------FSD--------------SN----NPIPY-NSVN-----LN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKVVTYI-GS--LHDNE-DYVD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGSAA----G-----------------------------------AP------------EDSSLAISSF-----S---------GL--ATD-A--KIAFF---DLASD-PSN----------NEPV--P------------PED---------------------------------------------------------------Y-----------SQ----L--------------YQPLY-N-----A------G----------A----RV-----------------------------------------HGDSWGSLSIQGYL-GS-YSDD--------------------AG-----------------------------------SIDDFL-------YTHP----DF-----I--------------------------------------------------------------------------------------I---------------LRAAG-NN--------EQYS----------------SLLS---------------------------------------------------------------------------------------------------------------------------------------Q-ATAK-N---------------------------V---IT---VG--A------------------------------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTTHESYTTDALEYSNFETVAKS-------------------TLNSLCQSFDDKYCTYTTAQCCTEYSTVKGLSG------------------------------------------------------------------------------------------CCTSYIKN---SYASIFSSQ---PE--LYNENNI-CSF-----S--S--------K-GPT-HDGRLKP----------------------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------QY--------------------------------I------------------------------------------------------------------TS-ARS---------------------------------------------------------------------------------------------------------------NGANTTD------QCGDGSLPNTNALL--S-ESG------TSMATPLAT----A---------------------------A------------------TT-ILRQYLV-------------------------------------------------------------------------------DGYYPTGSIVESNKLQPTGSLL---------------------KALM-------INNAQLLNGTFPL--SSTNTNPSNAVFDTFAGANFVQGWGSLRMSEWLYV-----------ESSGVKPKPSRWVGIGELG-KDKKASNWKEYSLSTGQNVSYCFTYKPSSSGSNS--G-GIPRIVATLVWTDPPSYS 551
 552 -------------------LQTANRLSPTVIFGTKDKLVNNDRID-------I-P-LRGK--------------------------G-Q--IL--------------S--------------------IAD---------------------------T--------------GLDG-S------H-------------C---------F--------------------------------FSD--------------SK----YPIPF-NQVN-----EN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKVVTYI--T--YHDNE-DYVN--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGSAA----G-----------------------------------TP------------EDSSWAISSF-----S---------GL--ATD-A--KIAFY---DLSSG-SSE------------PT--P------------PED---------------------------------------------------------------Y-----------SQ----M--------------YKPLY-D-----A------G----------A----RV-----------------------------------------HGDSWGSVSLQGYY-GG-YSDD--------------------AG-----------------------------------GIDAFL-------YEYP----EF-----S--------------------------------------------------------------------------------------I---------------LRAAG-NN--------ELFA----------------SLLA---------------------------------------------------------------------------------------------------------------------------------------Q-ATAK-N---------------------------A---IT---VG--A------------------------------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTAHVNYVSDALEYYDFSDNA---------------------NFQRPC-LFDKKYCNYTTAKCCSEVSNVKGLQL------------------------------------------------------------------------------------------CCPASIKQ---NASDSFTTQ---PQ--FYNENNM-GSF-----S--S--------K-GPT-HDGRLKP----------------------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------EY--------------------------------I------------------------------------------------------------------TS-ARS---------------------------------------------------------------------------------------------------------------NGENSTD------QCGDGSLPNANGLM--S-ISG------TSMATPLAT----A---------------------------A------------------TT-ILRQYLV-------------------------------------------------------------------------------DGYFPTGESVEENKLLPTGSLL---------------------KALM-------INNAQLLNGTYFW--SASSTNPSNAIFEQINGANLIQGWGALRMNNWLYV-----------KSSNPTP-PSRWIGIGGLG-KNQKATEWKEDSLSSGLNKSYCFTYKPSSSSSGSGGGGGTPRIVATLVWTDPPSYS 552
 553 -------------------FQTANRLSPKVVFGTKDTLVNNDRVD-------I-P-LRGK--------------------------G-Q--IL--------------S--------------------IAD---------------------------T--------------GLDG-S------H-------------C---------F--------------------------------FSD--------------SK----YPIPL-NSVN-----LN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKVVTYITTS--TSDDS-DKVD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------CGSAA----G-----------------------------------TP------------EDSSVNISSF-----S---------GL--ATD-A--KIAFF---DLASG-SSS------------LT--P------------PSD---------------------------------------------------------------L-----------KQ----L--------------YQPLY-D-----A------G----------A----RV-----------------------------------------HCDSWGSVSVEGYT-GS-YSSD--------------------TA-----------------------------------SIDDFL-------FTHP----DF-----I--------------------------------------------------------------------------------------I---------------LRAAG-NN--------EQYL----------------SLLT---------------------------------------------------------------------------------------------------------------------------------------Q-STAK-N---------------------------V---IT---VG--A------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QTIHENYLTDGPNYINYQSSVDI-------------------NQELIC-DFDSRYCNYTTAQCCLESNATTGLAS------------------------------------------------------------------------------------------CCPTLLRK---SVIDAANTQ---PL--LYNENNI-CSF-----S--S--------K-GPT-HDGRMKP----------------------------------------------------------------A-----L------V-----------------A-----P-------------G-----------------EY--------------------------------I------------------------------------------------------------------TS-ARS---------------------------------------------------------------------------------------------------------------NGANTTD------QCGDGSLPNTNALL--A-ISG------TSMATSFAA----A---------------------------A------------------TT-ILRQYLV-------------------------------------------------------------------------------DGYYPTGSIVESNKLQPTGSLL---------------------KALM-------INNAQLLNGTFQLITSSSITYPSNQVFENFAGASLVQGWGAIRMSNWLHVVNNNNSNNNNKTSDGI----TKFDGIGGLDLRLVKPNQWKEESLSTGQNTSYCFTYKPSSSSSNS--GNNIPRVVATLVWTDPPSYA 553
 554 --------------------------------------------------------LRGA--------------------------G-Q--II--------------S--------------------IAD---------------------------T--------------GLDT-G------H-------------C---------F--------------------------------FSD--------------SN----NAIPY-NTVN-----LN-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIVAYY-TD--SGDDQ-DFVD--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------CGSAV----G-----------------------------------SP------------QDSTWQVGQF-----N---------GL--ANE-S--KLAFY---DLSKD-STT----------QLSS--P------------PAD---------------------------------------------------------------Y-----------AK----M--------------YQTLY-D-----A------G----------A----RV-----------------------------------------HGDSWGSISPQTPF-GE-YSDG--------------------AA-----------------------------------SLDDFL-------YTHP----DF-----I--------------------------------------------------------------------------------------I---------------LRAAG-NG--------DQYG----------------ALLS---------------------------------------------------------------------------------------------------------------------------------------Q-ATAK-N---------------------------V---IT---VG--A------------------------------E-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSAHQSYITDTLVYSNYLPIANS-------------------YISQLC-AFDDKYCTYTPQQCCAEQNTLETLKR------------------------------------------------------------------------------------------CCLASIQL---SYNQTYSNS---SNYVLFNEDNI-MSS-----S--S--------R-GPT-HDGRMKP----------------------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------EY--------------------------------I------------------------------------------------------------------TS-ARS---------------------------------------------------------------------------------------------------------------NGANSTQ------QCGTGTLPNTDALL--A-LSG------TSMSTSFAT----A---------------------------A------------------TA-ILRQYLT-------------------------------------------------------------------------------EGYHPTGKPSEENKIKPTGSLL---------------------KALM-------INNAKFLNGTFYL--SSSGSYQSVSGGGSFTGADYIQGWGALRMGSWLYV-----------NSTGKDVK-NRFVAIGGLN-ETTKGSQWKEESLSTG---------------------------------------- 554
 555 ------------------------------------------------------N-ITGS--------------------------S-I--VV--------------G--------------------ITD---------------------------T--------------GLYV-D------H-------------D---------Q--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQ-----------------------------------------------------------------------------------------DSRDMYDDEDLTARKVIYYQTFANNVDEAEGVTC-------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------SGILA----GSSYS-------------------------------RK------------NSDF---------------------GI--ASS-A--RIAFMDIGKQESTCAGTS-GCKVSLET--PG--E------------VAN-------------------------------------L--------MKA-------------------------------QV--------------------A-----T------G----------A----KI-----------------------------------------FSFSWGTGANDYNT-QTQ-------------------------------------------------------------QVDEYI-------YDNP----EI-----L--------------------------------------------------------------------------------------I---------------IVAAG-NS--------GE-----------S---GDYTISS---------------------------------------------------------------------------------------------------------------------------------------P-SGAK-N---------------------------V---IS---VG--A------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AAASFSST---PCQSVLKEDTV-ASF-----S--S--------I-GPM-LDGRQKP----------------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------MS--------------------------------I------------------------------------------------------------------TS-SQS---------------------------------------------------------------------------------------------------------------EKPGSSIKSSAV-CS----------------LQG------TSQATPVVA----G---------------------------M------------------AVLIYE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 555
 556 -----------------------------------------------------AG-IRGN--------------------------D-V--VV--------------G--------------------ITD---------------------------T--------------GLYL-Y------H-------------D---------Q--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQ-----------------------------------------------------------------------------------------DERDIFVSIKLSARKVVMYNGWANKADEAETITC-------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLLA----GSSFS-------------------------------GK------------HANL---------------------GI--ADK-A--RIAFMDIGTQSETCTGQL-HCAVSLAT--PA--D------------ASD-------------------------------------L--------LES-------------------------------QI--------------------D-----A------G----------A----KI-----------------------------------------FSFSWGTPGSDYSS-QAR-------------------------------------------------------------DLDAFI-------YENP----DV-----L--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GE-----------SSTTGQRTISS---------------------------------------------------------------------------------------------------------------------------------------P-SGAK-N---------------------------V---IS---VG--A------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAASFTDF---GCPDVFNERTV-ASF-----S--S--------A-GPT-TDGRLKP----------------------------------------------------------------D-----V------V-----------------A-----P-------------G-----------------MS--------------------------------L------------------------------------------------------------------LS-SQS---------------------------------------------------------------------------------------------------------------EAPGSTTESSAT-CS----------------LQG------TSQATPVIT----G---------------------------V------------------AVLLYE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 556
 557 -----------------------------------------------------AG-IRGN--------------------------D-V--VV--------------G--------------------ITD---------------------------T--------------GLYL-Y------H-------------D---------Q--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DQ-----------------------------------------------------------------------------------------DERDIFVSIKLSARKVVMYNGWANKADEAETITC-------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGLLA----GSSFS-------------------------------GK------------HANL---------------------GI--ADK-A--RIAFMDIGTQSETCTGQL-HCAVSLAT--PA--D------------ASD-------------------------------------L--------LES-------------------------------QI--------------------D-----A------G----------A----KI-----------------------------------------FSFSWGTPGSDYSS-QAR-------------------------------------------------------------DLDAFI-------YENP----DV-----L--------------------------------------------------------------------------------------V---------------VVAAG-NS--------GE-----------SSTTGQRTISS---------------------------------------------------------------------------------------------------------------------------------------P-SGAK-N---------------------------V---IS---VG--A------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SAASFTDF---GCPDVFNERTV-ASF-----S--S--------A-GPT-TDGRLKP----------------------------------------------------------------D-----V------V-----------------A-----P-------------G-----------------MS--------------------------------L------------------------------------------------------------------LS-SQS---------------------------------------------------------------------------------------------------------------EAPGSTKESSAT-CS----------------LQG------TSQATPVIT----G---------------------------V------------------AVLLYE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 557
 558 --------------------TPSNKFAHYSIQSGSASTTSTPIWD-------VIG-IKGD--------------------------G-E--IV--------------G--------------------CAD---------------------------T--------------GIDI-N------H-------------C---------F--------------------------------FYD--------------TN-------PI-G--------ST-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HRKIISYS-SG--NGDQI-DEID--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-I-----------------------VGTII----GSTTV-------------------------------DP-----------------SVSEF-----S---------GG--APN-S--KVAFV---DLQVG-SGN----------G-LS--I------------QSN---------------------------------------------------------------L-----------TA----I--------------YQSTY-D-----Q------N----------A----KV-----------------------------------------HCDAWNSNI------GPFYTGV--------------------TE-----------------------------------MIDRFQ-------WDHP----DF-----L--------------------------------------------------------------------------------------V---------------VRSAG-NN--------VNFGFNSI-----------YTLSQ---------------------------------------------------------------------------------------------------------------------------------------E-STSK-N---------------------------S---LV---VG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSNQPSST-------------------YLSSIDYWDWDFIYNSIRTSVCTQGQSIYGITC-----------------------------------------------------------------SDVPTQTTSVDIQTQCCSNPILAKICCSTEIQQ---QYQTNST---------VYSEFIP-SLF-----S--G--------V-GPT-SDGRLKP----------------------------------------------------------------D-----L------L-----------------A-----P-------------G-----------------SP--------------------------------I------------------------------------------------------------------IS-SRS---------------------------------------------------------------------------------------------------------------LGPSSTINHCSPITSGIAT----SALI--A-MEG------SSQAAAVAT----S---------------------------A------------------AV-LVRQYYR-------------------------------------------------------------------------------DGYFINGKVNSSVGFQPSASLV---------------------KATL-------INTASINVDSTLE---------------------YSQGFGNIQLSKLITT-----------TNAQTTSL------------DIPSSIEKADPIINTGETNSYCFS------------LDSKADIDITLVWTDPAGSP 558
 559 ------------------------PGPFEPKNDGGRSATKTDLV-HQLGYHGNPASAPGS----------------------------I--VI--------------G--------------------VWD---------------------------C--------------GWVESN------H-------------P---------A--------------------------------FSGRLTIGDPDS--FTNGCGDVAGTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHA-------TH-V-----------------------AGTAA----GSGAG--------------------------------------------------------------SPSGRDLRGH--ADQ-A--TVLSYDVYDV------------------------------------DLE-------------------------------------V--------MQA--------------------------IQDYD--------------------------------------------------LDI-----------------------------------------SQNSWG---------PDTGGIC--------------DLTVLGV---------YDEFAAMFDALVHGTYSTEITKQI-------------------------A-----V--------------------------------------------------------------------------------------A----------------FANG-NEQSY--CP-----------NGWRTGS------GG----------------------------------------------------------------------------------------------------------------------------------------AMGKNV-------------------------------IA---VG--A------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N---------SDDKSM-TDF-----S--S--------F-GPTED----------------------------------------------------------------------GRVNPTV------V-----------------A-----P-------------GCEAGGEGAIWSTLPGPTYGAN--------------------------------------------------------------------------------------------------G--------------------------------------------------------------------------------------------------------------------------------------------------WCG------TSMATPAVS----G---------------------------I------------------LGLM----LEAYNLTYNSD-PLPATL----------------------------------------------------------------------------------------------------------RAIL-------VHT----------------------------------------------------------------------------------------------------AEDLG-NPGPDY---------------------- 559
 560 -----------------------WPGPFEPKNDGGRSATKTDLV-HQLGYHGNPASAPGS----------------------------I--VI--------------G--------------------VWD---------------------------C--------------GWVESN------H-------------P---------A--------------------------------FSGRLTIGDPDS--FTNGCGDVAGTD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHA-------TH-V-----------------------AGTAA----GSGAG--------------------------------------------------------------SPSGRDLRGH--ADQ-A--TVLSYDVYDV------------------------------------DLE-------------------------------------V--------MQA--------------------------IQDYD--------------------------------------------------LDI-----------------------------------------SQNSWG---------PDTGGIC--------------DLTVLGV---------YDEFAAMFDALVHGTYSTEITKQI-------------------------A-----V--------------------------------------------------------------------------------------A----------------FANG-NEQSY--CP-----------NGWRTGS------GG----------------------------------------------------------------------------------------------------------------------------------------AMGKNV-------------------------------IA---VG--A------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N---------SDDKSM-TDF-----S--S--------F-GPTED----------------------------------------------------------------------GRVNPTV------V-----------------A-----P-------------GCEAGGEGAIWSTLPGPTYGAN--------------------------------------------------------------------------------------------------G--------------------------------------------------------------------------------------------------------------------------------------------------WCG------TSMATPAVS----G---------------------------I------------------LGLM----LEAYNLTYNSD-PLPATL----------------------------------------------------------------------------------------------------------RAIL-------VHT----------------------------------------------------------------------------------------------------AEDLG-NPGPDYQFGYGHVDALAAIN-------- 560
 561 ----------------------------ITYNRIAAQTVRTDAVWSSFNLDGS------G----------------------------I--EI--------------G--------------------LWD---------------------------E--------------GAVYEY------H-------------D---------S--------------------------------F--REGIYGPRHVFFIDSTG--SEVS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHS-------TH-V-----------------------AGTIV----ADNDN--------------------------------------------------------------YNS----KGM--ADK-S--VLYSRDWNAG------------------------------------FVE-------------------------------------M--------TNA--------------------------AAGLDPN--------------------------------------------FTTPLLL-----------------------------------------SNHSYG---------QNPGWVW-------------GDLRNSGTNAWYWMAEDYQNEDPNF-----GNYHDSLTFNIDLIAFNAPY---------------YT-----I--------------------------------------------------------------------------------------V----------------WAAG-NDRGQ--GPEPFTSHWVWDGEKWVSSTSYHPKDGGDDGFDCIP------------------------------------------------------------------------------------------------------------------------------PEGVAKNI-------------------------------IT---VG--A------------------------------V--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DDIPYGYTSPSDVKQINTNF-----S--V--------W-GPTKD----------------------------------------------------------------------GRIKPDI------V-----------------A-----N-------------G------DALYSTLPNNLYGNTIKG----------------------------------------------------------------------------------------------LT--------------------------------------------------------------------------------------------------------------------------------------------------ASG------TSMAAPNVT----G---------------------------S------------------LALL----LQHYKNTHNNTVPLSSTL----------------------------------------------------------------------------------------------------------KAIV-------IHT----------------------------------------------------------------------------------------------------ADEAGENPGPDYKYGWGLLNTYKAAQ-------- 561
 562 ---------------------------------------------------------------------------------------------------------------------------------IDDVHGFDFAGSCESDWRSTKN-------------------TNCGPRPDP------Q-------------D---------T--------------------------------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-C-----------------------SGIVA----ALRN----------------------------------------------------------------------IGI--APR-V--KVMCL---KV-----------------------ATPNG----AFYTSH--------------------------------------I--------LKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------YDYAYNMGAHIASCSFGPAEPNLQP-TPQEVEEMWNETKFYKTALDP---------MVKK----GM-----L--------------------------------------------------------------------------------------V---------------VAAAG-N-------ENTPLES--LDAVNSTYNPCFMA------------------------------------------------------------------------------------------------------------------------------------------RYFADS-M-------------------------------LC---VM--A-----------TNPNDSR-WFEIAANKPIGS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------Y-GTKYA----------------------------------------------------------------------D-----I------G-----------------A-----P-------------G-----------------RQ--------------------------------I------------------------------------------------------------------YS--------------------------------------------------------------------------------------------------------------------TVPKLIGNG---------------YATYAYKTG------SSMATPMTA----G---------------------------V------------------GALV----L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 562
 563 --------VKAKDAWNVTQGTPEVIVAVVDTGCDLTHPDLKDNLWINTKEIPGNG-VDDD--------------------------G-N--GL------------------------------------IDDVYGYDFAGTCENDYPS----------------------DGCGPKPDP------Q-------------D---------T--------------------------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------SH-C-----------------------AGIVG----AVRNN-----------------------------------------------------------------GVGISGI--APR-V--KIMCL---KV-----------------------STPSN----NFYTAH--------------------------------------I--------LKA-----------------------------------------------------------------------------------------------------------------------------------------------------------------YDYAYRMGAHVVSCSFGPAEPNMKTISPDELAAYVAERNLYRAALQP---------MVDK----NM-----L--------------------------------------------------------------------------------------I---------------IAAAG-N-------ENTNLDQ--LDQYNTTYMPCFMA------------------------------------------------------------------------------------------------------------------------------------------KEFPEN-M-------------------------------LC---VT--A-----------TNQDDVR-WAEIANNKPVGS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--------F-GLKYA----------------------------------------------------------------------D-----I------G-----------------A-----P-------------G-----------------RL--------------------------------I------------------------------------------------------------------MS--------------------------------------------------------------------------------------------------------------------STPPVAGNS---------------MTRWNLKTG------SSMATPMVS----G---------------------------I------------------GALV----LSVLGTGTGNYFQGKEA-----------------------------------------------------------------------------------------------------------RKII-------VESADPKVGLPVSTGRRVN---------------------------------------------------------------------------------------------------------------------- 563
 564 ----------------------------------IIRFRGAQEAV-------RSV-SRGL--------------------------RNV--VL--------------A--------------------IVD---------------------------S--------------GVDV-S------H-------------P---------D--------------------------------L-----------------------------INQFW-KNPD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGSIGFNFLDDNTN------------VT-----------------------------------------------------------------------------------------D---E---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------AGIAG----AQTNN-------------------------------SL-------------------------------------GI--AGV-ADVKLMIL---KF---VGSD----------R-TG--P------------LSG-------------------------------------A--------LKA--------------L-----------DY---AV--------------------G-----M------G----------A----AV-----------------------------------------SSHSYG-------------------------------------G--------------------------NVPSRIFENAIRN---------AANA----GH-----I--------------------------------------------------------------------------------------V---------------VAASG-NE--------GM---------NLDETPTYPCSYSRSI------------------------------------------------------------------------------------------------------------------------------------P-S--------------------------------M---LC---VG--A------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SSTPTSPVSL-ASF-----S--N--------I-G---S--------------------VV------------------------------------------------N-----I------V-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LS-TYL-----------------------------------------------------------------------------------------------SG------------------------SY-AF----------------LSG------TSMATPQVA----G---------------------------V------------------AA-V----LATLGLA-------GQS-------------------------------------------------------------------------------------I---------------------TDSI-------TRS-----------------------------------------------------------------------------------------RTASLENPLSLQNLGELDALNAVNEGLDQPTSPPRQPSSTRLSSS 564
 565 ----------GLLGGGA-------PD--------------------------------------------------------------V--IV--------------A--------------------VVD---------------------------T--------------GFDI-D------H-------------P---------D--------------------------------L---------------------K----------------PNLWVNPGEVPGDGIDNDGNDVRAARNAGFIDDINGAATAKKKVQAAALTSPTVRAT------------------------------------------------------------------------------------------------------------------------------------------YATQLRPMCKPDADVRPE------------SS-----------------------------------------------------------------------------------------D---T------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AGIVA----A----------------------------------------------------------------------------------------------V---FDAS----------G-RV--Y------------ASH-------------------------------------V--------VAA--------------Y-----------AY---AQ--------------------R-----M------G----------A----HI-----------------------------------------VSCSFGPDTP-NLQ-PQPYEVA--------------------EM--------------------------VAQESLYSSAVTP-L--------ESK----GV-----L--------------------------------------------------------------------------------------L---------------VAAAG-NE--------LT---------DLNGLASVKSNYLPCTL-----------------------------------------------------------------------------------------------------------------------------------P-N--S-------N---------------------V---MC---IT--G------------------------------S-----------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-------------------------------------------------------------------------------------LD-------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AITG---MAG------NM-PVG-----V--N--------Y-GT--A--------------------VV------------------------------------------------D-----M------A-----------------A-----P-------------G-----------------QD--------------------------------I------------------------------------------------------------------YN-TFP-------------------------------------------------------------------------------------------------------------ISLG--------SY-GN----------------KTG------SSMATPLVA----G---------------------------V------------------AA-L----VASVVGA-------VGPLVA-----------------------------------------------------------SPNYYQASS--------------V---------------------KSLL-------LET-------------------------AD------------------------------------------------------------------------KLPGLP--VIGGRRLNAQRAVE------------- 565
 566 ------------QAYTLNDPQLSTTWWFDRINVTGAWRLLNVNAT-------DPQ-QRTS--------------------------D-V--VI--------------G--------------------VTD---------------------------S--------------GAFV-N------H-------------P---------D--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IGSFWENPAEIDNDLRDNDNNTYIDDV----YGACFANSVC-------------------------------------SPTSLNSN-------------------------LSRCGIGKNTFAWNNVNDIN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TK-I-----------------------AGVIG----ARPNN-------------------------------GI------------GLA----------------------GV--APN-L--RQMVL---KV---VDDT------------YFQYA------------YSD-------------------------------------V--------VRA--------------I-----------DY--------------------------------GYAKG-A---------------RI-----------------------------------------FSMSFGQDARTS-A-TPTNKP----------------------------------------------------------SLDAAA-TAYRN-LFNK--YSNA-----L--------------------------------------------------------------------------------------F---------------VAAAG-NE--------WT---------SLEGWRSGNYTYS---------------------------------------------------------------------------------------------------------------------------------------P-CMIATDNT-----------------------------LC---VG--G------------------------------TNVNDT--------------IFYV--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FAF-----N--Q--------Q-AGT-NFGPTTV----------------------------------------------------------------D-----M------G-----------------A-----P-------------A-----------------HS--------------------------------I------------------------------------------------------------------YTTDIA-------------------------------------------------------------------------------------------------------------------------------------VNRNY--SAPSG------TSFATPMVA----A---------------------------V------------------AGLV----------LSALGGTGRATPQT-----------------------------------------------------------------PLQ--------------I---------------------KNIL-------MSS---------------------------------------------------------------------------------------------------GDLLPSLNNQFKSARRLNAANAVAAALTLARTNRT 566
 567 -----------------------------FNNQWGLEAINAQYAY-------ARG-YSGY--------------------------G-I--NI--------------G--------------------VLD---------------------------A--------------KL-F-Q------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGKL-------------------------------------SQLSGNLP-------------------------YDFETEEDG--------SISFE------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------VH-V-----------------------AGIAA----ARRDG-------------------------------TG------------MH-----------------------GV--AFG-A--TLTTG---NIPDSNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLE-FARH----GK-----L--------------------------------------------------------------------------------------I---------------VFAAG-NENNY--NV----------------------PMHSATLPYLF-------------------------------------------------------------------------------------------------------------------------------PDVLDRYLIVANLT---------------------PDDELH---VT--S------------------------------TSC-GHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----C----------------------------------------------------------------------------------------------V------S-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------YS-AAG-----------------------------------------------------------------------------------------------NFISRTGGPITEAALNRGELTEEPD--Y-RE----------------ETG------TSMAAPHVT----G---------------------------A------------------AAVL----MQ------------RFPYMT-----------------------------------------------------------------AEQ--------------I---------------------STVL-------KTT----------------------------------------------------------------------------------AS----------------DLGAPGIDNR---FGWGKINLKEAI--------- 567
 568 ---------------------------PEFNNQWGLEAINAQYAY-------ARG-YNGY--------------------------G-I--NI--------------G--------------------VLD---------------------------A--------------KL-F-Q------H-------------P---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NGKL-------------------------------------SQLSGHLP-------------------------YDFETEEDG--------SISFE------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------VH-V-----------------------AGIAA----ARRDG-------------------------------TG------------MH-----------------------GV--AFG-A--TLTTG---NIPDSNN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VL---ARH----GK-----L--------------------------------------------------------------------------------------I---------------VFAAG-NENNY--NV----------------------PMHSATLPYLF-------------------------------------------------------------------------------------------------------------------------------PDVLDRYLIVANLT---------------------PDDELH---VT--S------------------------------TSC-GHT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----C----------------------------------------------------------------------------------------------V------S-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------YS-AAG-----------------------------------------------------------------------------------------------NFISRTGGPITEAALNRGELTEEPD--Y-RE----------------ETG------TSMAAPHVT----G---------------------------A------------------AAVL----MQ------------RFPYMT-----------------------------------------------------------------AEQ--------------I---------------------STVL-------KTT----------------------------------------------------------------------------------AS----------------DLGAPGIDNR---FGWGKINLKEAI--------- 568
 569 --------------------APDSWKTAEFNRQWGLEAISAEFAY-------ARG-YTGK--------------------------G-I--TI--------------G--------------------VID---------------------------N--------------AI-L-S------H-------------S---------E--------------------------------F-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SGKL-------------------------------------TRLD-NGS-------------------------YNFSYDKQD--------NMSFG------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TH-V-----------------------AGIAA----AKRDG-------------------------------AG------------MH-----------------------GV--AFD-A--DIIGT---KLNDYGNRN----------------G------------REE-------------------------------------L--------I----------------------------------Q--------------------------------------------SAA--RV-----------------------------------------INNSWGIAPDIRRD-AKGDIIW-------------LPNGR--PDYVAFVKSEVIAE-----MMRSKSSVEWGSEQPVPTGGHSAM-STLLR-AARH----GK-----L--------------------------------------------------------------------------------------I---------------VFSAG-NYNNY--NI----------------------PEAQKSLPYAF-------------------------------------------------------------------------------------------------------------------------------PDVLNNYLIVTNLS---------------------DENQLS---VS--S------------------------------TSC-GQT-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASY-----C----------------------------------------------------------------------------------------------V------S-----------------A-----P-------------G-----------------SD--------------------------------I------------------------------------------------------------------YS-TVG-----------------------------------------------------------------------------------------------RLESNTGGAVNREAYNKGELSLNPG--Y-GN----------------KSG------TSMAAPHVT----G---------------------------V------------------AAVL----MQ------------RFPYMS-----------------------------------------------------------------ADQ--------------I---------------------SAVI-------KTT----------------------------------------------------------------------------------AT----------------DLGVAGIDNL---FGWGRVNLRDAIN-------- 569
 570 ---------------------------------------------------------SGK--------------------------G-V--KL--------------G--------------------VLD---------------------------G--------------GFVV-Q------H-------------P-------------------------------------------LNSSKLHPSSFKLTSPDGKVLTYDPSYLQFEVKPVEQNGKKDLTALFE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------LG-V-----------------------SGVIS----AKASKKDGFKG----------------------------------------------------------------GV--AKD-AEIHIATNTPNRSLAELIAEA-QQSESEDEG------------------QGDSKNQKPNFDELAKDDLLLTKEKRLSFERLEWATALNKL----------------------------------------------------------------------------------------VERNLFA-----------------------------------------INNSWNLD-PISDNIADFDK-LYHSLSTDKQNSLLQAVLNAKRK--------------------------------------------------------NT-----L--------------------------------------------------------------------------------------L---------------VFAAG-N---------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESKKQ------------------------------------VGVMA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLPRYLPELEKHYLSVVAVDNKNNLAEY-----S--N--------HCGVSKNWCVA-------------------------------------------------------------------------------------------------A-----P-------------G-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NLAILNAIPDNKLKPQYSLDKEEG------TSLATPVVT----G---------------------------A------------------LAIL--------------------------------------------------------------------------------------------------------------------------------KERFNYLVPTQIRD------------------------------------------------------------------------------------------------TLLTTATDLGEKGVDDKYGWGVINIAKAI--------- 570
 571 --------------------DPASWRSAEYQQDWGLERMRADQAY-------AAG-IDGQ--------------------------G-V--KI--------------G--------------------EMD---------------------------S--------------GFDP-S------H-------------P---------D--------------------------------T----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PASRY-------------------------------------QPVTASGT-------------------------YVDGTPFSVSGAMNGNND----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TH-V-----------------------GGTLG----ASRDG-------------------------------VG------------MH-----------------------GV--AYA-A--QVYVA------------------------NTNQN------------DSF----------------------------------------------LFGPTPDPNYFKAAYQAL----------------AD--------------------------------------------AGV--RA-----------------------------------------INNSWGSQPKDVSY-E------------------------------------------------------TLDGLHAAYAQHYGR-STWLD-AAAGVSRQGV-----I--------------------------------------------------------------------------------------N---------------VFSAG-NS--------GY-------------------------------------------------------------------------------------------------------------------------------------------------------------ANASVRSALPYFQPDLEGHW-------------------LA---VSGLD------------------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GQR-----Y--N--------RCG--------------------------------------------------------------------------------IAKYWCIT-----------------T-----P-------------G-----------------RL--------------------------------I------------------------------------------------------------------NS-TMP-----------------------------------------------------------------------------------------------------------------------GGGY-AN----------------KSG------TSMAAPHAT----G---------------------------A------------------LALV----MQ------------RYPYLN-----------------------------------------------------------------NEQ--------------A---------------------LQVL-------LTTATQLDGTPTGAPTDTVGWGVPDLGRAMHGPGQLLGRFEANLPAGLRDEWSNPISDSALLQRQAEDAAEHAAWQRTLKDKGWENGLPAGASQQERTDYAIGMARDQAAAQRQYQG-------------------- 571
 572 ------------------------------------------------------HNLDGR--------------------------G-I--TV--------------T--------------------VLD---------------------------Q--------------DTEE-KEEWIGKNKTSFKPFLATGRYK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------EE-C-----------------------ASVLH-------------------------------------------------------------------------------TI--CPN-A----------SI-----------------------LCANNVEEDYHLAFTD----------------------------------------------CKN-----------------------------------------------------------------------------HEPPIDV-----------------------------------------ISYSLSMPSFYYDMCR---------------------------------------------------------------VVNE---------AVVA----GK-----I--------------------------------------------------------------------------------------I---------------VFAAG-NTGKKERNTVEY-------------------------------------------------------------------------------------------------------------------------------------------------------------PGRIGN-----------------------------I---LV---VGGRD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESHNRIGFS-----------AIGREMDF---------------------------------------------------------------------------L------------------------AEGEI--------------------------------------------------------------------------------------------------------------------------------------GT--------------------------------------------------------------------------------------------------------------------------------------------------YSG------TSYAAPVVA----G---------------------------Y------------------IALL----------------------------------------------------------------------------------------------------------L------------------QFIKENMNTDQDKIRAWSKN----------------------------------------------------------------------------------------------------------------------------------- 572
 573 ----------------------------------------------------------GR--------------------------G-I--SV--------------T--------------------VLD---------------------------K--------------DMEE-KEEWIGENKTSFKPFPATGTYK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------KD-C-----------------------ASVLH-------------------------------------------------------------------------------TI--CPN-A----------SI-----------------------LCANNVEELYHLAFTD----------------------------------------------CIN-----------------------------------------------------------------------------HEPPIDV-----------------------------------------ISYSISIPSFYYDMCR---------------------------------------------------------------VVNE---------AVVT----GK-----I--------------------------------------------------------------------------------------I---------------VFAAG-NTGKKERNTVEY-------------------------------------------------------------------------------------------------------------------------------------------------------------PGRIGN-----------------------------I---LV---VGGRD--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ESHNRIGFS-----------SVGREMDF---------------------------------------------------------------------------L------------------------AEGEI--------------------------------------------------------------------------------------------------------------------------------------GT--------------------------------------------------------------------------------------------------------------------------------------------------YSG------TSFAAPVVA----G---------------------------Y------------------IALL----------------------------------------------------------------------------------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 573
 574 ---------------------------YVLG-------KLRLPQA-------HTL-AHGA--------------------------N-V--TV--------------A--------------------VID---------------------------S--------------GIDA-K------H-------------P---------E--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ANSIAD---NFDALGSAEGP----------------------------------------------------------------------------------------------------------------------H--------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TG-I-----------------------AGAIV----A-----------------------------------HA------------RLM----------------------GS--APE-A--RIIAI---RA---FGGT----------TGGA--E------------SSSYI-----------------------------------I--------LRS--------------L-----------NY---AA--------------------E-----H------G----------A----QI-----------------------------------------VNMSFA---------GP----K--------------------DA--------------------------VIER-----AIAA---------TAAR----GL-----V--------------------------------------------------------------------------------------L---------------IAAAG-NA------------------------GAKSPPLY---------------------------------------------------------------------------------------------------------------------------------------P-AANP-N---------------------------V---IA---VS--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------QQ-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-FTA-----S--N--------R-G--------------------------------------------------------------------------NYIA--L------A-----------------A-----P-------------G-----------------VD--------------------------------I---------------------------------------------------------------------------------------------FLPAP------------------EGK---------------------------------------------------------------------------Y-QM----------------TSG------TSFSAAYVS----G---------------------------V------------------AALL----LE------------RNYALK-----------------------------------------------------------------PEA--------------L---------------------RMTL-------AKT-----------------------------------------------------------------------------------------------------ARDLGSPGRDDLFGDGEADAFAA---------- 574
 575 ----------------------------VTPTGGPFFAKQDKALNTIDLKMAHDLKLRGY--------------------------R-V--KV--------------A--------------------VVD---------------------------E--------------GVRS-D------H-------------P------------------------------------------LLNVEKKYGGDY---MADGTRTYPDP----------KRQGR--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TS-V-----------------------ALVLA----GQDT--DTYRG----------------------------------------------------------------GV--APN-ADLY-SANIGTRA-----------GHVSDEA---------------------------------------------AFH------AWNDL----------------------------------------------------------------------------------------LGHGIKI-----------------------------------------FNNSFATEGPEGEQRVKEDRNEYHS-AANKQNTYIGRLDRLVRD--------------------------------------------------------GA-----L--------------------------------------------------------------------------------------L---------------IFAAG-NGR----------------------------------------------------------------------------------------------------------------------------------------------------------------------PSGRAYSE------------------------------------VGSVG-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RTPRVEPHLQRGLIVVTAVDENGRLETW-----A--N--------RCGQAQQWCLA-------------------------------------------------------------------------------------------------A-----P-------------S-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TAYLPGLDKDN---PD-SIHVEQG------TSLSAPLVT----G---------------------------A------------------AVLV--------------------------------------------------------------------------------------------------------------------------------QDRFRWMDNDNLRT------------------------------------------------------------------------------------------------TLLTTAQDKGPYGVDPQYGWGVLDVGRAVQ-------- 575
 576 ---------------------------------------------------------------AEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDSEFAKFSFTQ--------------DGSPFPVKEPE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRHEV-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------I--------RAT--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGISSAS-------------VWSELLSRM------------------------------------------------GRNN----ER-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKLSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGVTGSRFGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLKPD-------GKTGIGSG------TSEATAIVS----G---------------------------V------------------LAAM----VS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYPSLADKVTEGRV---------------------------------------------------------------------------------------------------------------------- 576
 577 ---------------------------------------------------------------AEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDSEFAKFSFTQ--------------DGSPFPVKEPE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRHEV-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------I--------RAT--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGISSAS-------------VWSELLSRM------------------------------------------------GRNN----ER-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKLSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGVTGSRFGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLKPD-------GKTGIGSG------TSEATAIVS----G---------------------------V------------------LAAM----VS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYPSLADKVTEGRV---------------------------------------------------------------------------------------------------------------------- 577
 578 ---------------------------------------------------------------AEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDSEFAKFSFTQ--------------DGSPFPVKEPE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRHEV-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------I--------RAT--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGISSAS-------------VWSELLSRM------------------------------------------------GRNN----ER-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKLSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGVTGSRFGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLRPD-------GKTGIGSG------TSEATAIVS----G---------------------------V------------------LAAM----VS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYSSLADKVTEGRV---------------------------------------------------------------------------------------------------------------------- 578
 579 ---------------------------------------------------------------AEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDSEFAKFSFTQ--------------DGSPFPVKEPE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRHEV-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------I--------RAT--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGISSAS-------------VWSELLSRM------------------------------------------------GRNN----ER-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKMSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGVTGSRFGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLRPD-------GKTGIGSG------TSEATAIVS----G---------------------------V------------------LAAM----VS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYPSLADKVTEGRV---------------------------------------------------------------------------------------------------------------------- 579
 580 ---------------------------------------------------------------AEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDSEFAKFSFTQ--------------DGSPFPVKEPE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRHGV-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------L--------RAT--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGISSAS-------------VWSELLSRM------------------------------------------------GRNN----ER-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKLSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGVTGSRFGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLRPD-------GKTGIGSG------TSEATAIVS----G---------------------------V------------------LAAM----VS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYPSLADKVTEGRV---------------------------------------------------------------------------------------------------------------------- 580
 581 ----------------------------------------------------LFLLFISASARAEKPWYFDAIGLTETTMSLTDKNTPV--VV--------------S--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------IGGLSDSEFAKFSFTQ--------------DGSPFPVKKSE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASLIA----SRYGI-------------------------------------------------Y--------------------GV--YPH-A--LISSR---RV---IPD-------------GV--Q------------DSW-------------------------------------I--------RAI--------------ESIMSNVFLAPGEE------------------------------------------------------KI-----------------------------------------INISGG--------QKGVASAS-------------VWTELLSRM------------------------------------------------GRNN----DR-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRKLSAQQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPVSSVNKKQDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYRKGETPVLH--------GGGITGSRFGNNWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TFLRPD-------AKTGTGSG------TSEATAIVS----G---------------------------V------------------LAAM----TS------------CNPRAT----------------------------------------------------------------------------------A------------------TELKRTL-------LESADKYPSLVDKVTEGR----------------------------------------------------------------------------------------------------------------------- 581
 582 -----------------------------------------------------------------PQWYFDVIGINDKVMHYTNKNSPV--AV--------------T--------------------VVD---------------------------S--------------GV----------------------------------A--------------------------------F-----------VGGLSDAEFAKYSYTK--------------DGSPYPVKGDE-------ALY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TA-M-----------------------ASIIA----SRYGI-------------------------------------------------L--------------------GV--YQD-A--MISNR---RV---IPN-------------GV--T------------DSW-------------------------------------I--------KAI--------------EAVSLNNNLSPGQE------------------------------------------------------KI-----------------------------------------INVSGG--------QKGSHSAT-------------AWTDLLSRL------------------------------------------------GKEN----DK-----L--------------------------------------------------------------------------------------I---------------VAAVG-NDGAD--IRTITPEQRIW-------------------------------------------------------------------------------------------------------------------------------------------------------PAAYHPSSKINKKFDP-------------------V---IR---VA--A------------------------------L-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQYTKSQTPSLH--------SGGITGSRYGNGWV---------------------------------------------------------------D-----I------A-----------------A-----P-------------G-----------------QN--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NYLKPD-------NTIGVGSG------TSEATAIVS----G---------------------------V------------------LAAM----SS------------CNPRAT----------------------------------------------------------------------------------A------------------QELKKTL-------LDTADQYSSLADKVTDGR----------------------------------------------------------------------------------------------------------------------- 582
 583 -------------------------------------------PN-------DPL-YLGNAQFPQGQWGLRRINPEAGWDLLPRRGPKI--IV--------------A--------------------VID---------------------------S--------------GVN--P------H-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VGNV-------------------------------------LFNRRYNA-------------------------VTD-------TVGGDVTDTF-----------------------------IP--------------------------------------------------------------------------------------------------------------------------------------------HG-------TG-I-----------------------AGNIA----ATTNN-------------------------------LT------------GMA----------------------GT--SFNTV--NILPI---KV---VDEN----------N-GE--D------------EES-------------------------------------VQPAAL---ARA--------------I-----------DY---AW---------------------------------R----------NGA--RV-----------------------------------------INMSVT-QGDPLLV-GAANTIR-------------YTAFPEVQA-----------------------------------AINR---------AFAA----GA-----V--------------------------------------------------------------------------------------L---------------VAMAG-ND--------GIGQVAF--------------------------------------------------------------------------------------------------------------------------------------------------------PAAYDN-----------------------------V---IA---VS--G------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TMQDTL-LAV-----S--N--------S-GPQ-I----------------------------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------DL--------------------------------I------------------------------------------------------------------L--TMD-----------------------------------------------------------------------------------------ANNFN-G--------------------------YDST----------------FTG------TSIAASFVG----G---------------------------L------------------AALIFSVNPKLRNTD-----------------------------------------------------------------------------------------------V---------------------VRII-------EGT------------------------------------------------------------------------------AHQPGTP-----------------------GTLVISGRGKGKGPQAL--------- 583
 584 ----------------RGVRVGDRTYVQSYLTRIGADEAWQALDA-------AGR-SKNG----------------------------V--LT--------------A--------------------VLD---------------------------T--------------GADK-N------H-------------L---------D--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGRLLMGCTFDNQGGFAVGAPEVSANSS-----------------------------------------------------------------------------------------Q---G---------------------R--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-S-----------------------AGLIG----ATT--------------------------------------------------------------DNGLGL---SGL--LWH-G--TLLPV---KV---LGED------------GA--S------------TVS-------------------------------------L--------IGG--------------L-----------NY---AA--------------------A-----Q------G----------A----RV-----------------------------------------INMSLG----------IPGKLS--------------------DP--------------------------ALNQ-----AITA---------A-AR----QA-----V--------------------------------------------------------------------------------------L---------------VAAAG-NT--------SN---------D--------GIYF---------------------------------------------------------------------------------------------------------------------------------------P-ASHP-D---------------------------V---IA---VG--A------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------REDRLACYSA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RP-GAA-----S--G--------S-R------------------------QL------------------------------------------------D-----I------V-----------------A-----P-------------GGNAGTSASVTSSAAGCLVS----------------------------GPDDL------------------------------------------------------------------LT-LNT-----------------------------------------------------------------------------------------------TEQNGYAL---------------------------------------RAG------TSEAAPLVS----G---------------------------V------------------VS-L----MW----G-------ANPSLS-----------------------------------------------------------------AAQ--------------V---------------------RARL-------LASARQVDGLKVLD--------------------------------------------------------------------------------------------------------------------------- 584
 585 ---------------------------------GATKIKATDVW--------ATS-NTGQ--------------------------G-I--VV--------------G--------------------TID---------------------------T--------------GVRA-T------H-------------E---------T--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNNWIGS-----------YG-WYDP--AQKTA-TP-------------------------------------------------------------------------------------F---D---A---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------MATIV----G------------------------------------G------------KGV----------------------GI--APG-A--KWMSC---KA---C-SS----------S-CS--L-------------SL-------------------------------------M--------NQC--------------A-----------QF---ML-------CPTDTNGN---NCN-----P------A----------KAP--HI-----------------------------------------VSNSWG-----TGQ-GM--------------------------T--------------------------YFQP-----MIDA---------WSAA----RI-----I--------------------------------------------------------------------------------------P---------------IFSAG-NS--------GANG-----------CS---SVVS---------------------------------------------------------------------------------------------------------------------------------------P-GDSA-K---------------------------V---FS---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------TS-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AL-GSF-----S--S--------I-GPA-VNG----------LVKP------------------------------------------------------D-----F------I-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------RS---------------------------------------------------------------------------------------------------AWNGNSA-------------------DY-MS----------------LSG------TSMAAPHLA----G---------------------------T------------------IA-L----AL----S-------ARPGFC--FDT-----------------------------------------------------------------------------M---------------------KEVL-------MS--------------------------------------------------------------------------------------------------------STDRSLPST---------------------- 585
 586 ---------------------------TSAAQWGVSKINAPDVW--------ATG-NTGQ--------------------------G-V--VI--------------G--------------------SID---------------------------T--------------GVRG-T------H-------------E---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASSYRKS-----------YG-WFDP--ELRAF-AP-------------------------------------------------------------------------------------Y---D---S---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------TGIMV----G------------------------------------Q------------FGF----------------------GV--APG-A--TWMAC---KG---CRAQ----------G-CY--G-------------SD-------------------------------------L--------LAC--------------F-----------QF---ML-------CPTTPSGT---SKD-----C------S----------KAP--NI-----------------------------------------VNNSWG-----GGQ-GL--------------------------T--------------------------MFDG-----VINA---------WRAA----GI-----I--------------------------------------------------------------------------------------P---------------VVAAG-NT--------GPN------------CG---TIAS---------------------------------------------------------------------------------------------------------------------------------------P-GDSA-S---------------------------V---IT---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------IN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GL-ASF-----S--S--------K-GPT-VRG----------LRKP------------------------------------------------------D-----V------A-----------------A-----P-------------G-----------------AL--------------------------------V------------------------------------------------------------------LS---------------------------------------------------------------------------------------------------SCWTDDA-------------------SY-CF----------------KSG------SSMAAPHVA----G---------------------------A------------------IA-L----YL----S-------ANPGTS--YDK-----------------------------------------------------------------------------I---------------------KDVL-------QSR-------------------------SVTTT----------------------------------------------------------LTTPTGY----ACGKTQDRNFPNNQYGYGRVDIFKAL--------- 586
 587 --------------------------------WGVGKIGAEVVWA-------K-G-IMGA--------------------------N-V--TI--------------A--------------------TID---------------------------T--------------GVRA-S------H-------------E---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSNFQG-----------DYG-WFDP--ETKSG-AP-------------------------------------------------------------------------------------F---D---L---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------IGSIV----------------------------------------GV------------NGV----------------------GV--APK-A--NWMAC---RG---CRST----------T-LC--L------------ESS-------------------------------------L--------LAC--------------A-----------QF---VL-------CPTDPKGH---NPK-----C------S----------KAP--RV-----------------------------------------VNNSWG-A---VQG-A-A-------------------------N---------------------------FSA-----IIAA---------WQAA----EI-----I--------------------------------------------------------------------------------------P---------------VFSIG-N---------SGSF----NS-----CG---VVAS---------------------------------------------------------------------------------------------------------------------------------------P-GDSS-M---------------------------V---IG---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------R-------------------------------------------------------------------------------------SN-------E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FL-LPQ-----S--S--------T-GP--SAD-------G--RIKP------------------------------------------------------D-----I------V-----------------A-----P-------------G-----------------DR--------------------------------I------------------------------------------------------------------YS---------------------------------------------------------------------------------------------------AWWTRDN-------------------VY-VI----------------ASG------TSMASPHVA----G---------------------------A------------------VA-L----LL----S-------AQPDLT--YDQ-----------------------------------------------------------------------------I---------------------WGAL-----------------------------------AISAA---K-----------------------------------------------------DRSVVDNAAFHSSCGNISALMFPNNIFGYGRLDVDRAV--------- 587
 588 DVALLMADHQLQMSPPATTTAVSCSATSNNVCWNIARIGADRVWR-------EFG-VTGS--------------------------G-I--TV--------------A--------------------NID---------------------------S--------------GVQY-T------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VNQYRGNLGSNTF--DHNYN-WFDP--VGNQP-AP-------------------------------------------------------------------------------------V---D---A---------------------G--------------------------------------------------------------------------------------------------------------------------------------------------THG-------TH-V-----------------------MGTMV----A-NPP-------------------------------GE------------PAM----------------------GV--APG-A--RWIAA---RA---CSSV----------T--C--N------------DSD-------------------------------------I--------IAA--------------A-----------QW---ML-------APTDLAGN---NPR-----P------S----------LRP--HI-----------------------------------------LNNSWS-F---DSG-GNP-------------------------V---------------------------YSG-----YTTA---------WQAA----GI-----F--------------------------------------------------------------------------------------V---------------VFAAG-NI--------SSNF----TT-----CS---SVAS---------------------------------------------------------------------------------------------------------------------------------------P-GDYS-N---------------------------V---VA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------QN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LL-SYF-----S--R--------I-GP--TTD-------G--RIKP------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------QG--------------------------------I------------------------------------------------------------------VS-TVT-----------------------------------------------------------------------------------------------STITDAN-------------------TF-GA----------------LSG------TSMAAPHVA----G---------------------------A------------------VA-L----LW----S-------AKPQLIGDYDA-----------------------------------------------------------------------------T---------------------YALL-------TGT-------------------------ALPLT---G-----------------------------------------------------DSRYM--GANHSAC---RPDTVPNNIYGYGRLDIFNAVAAARVTVPW 588
 589 ---------------------------------------APQLW--------AKG-ATGK--------------------------N-V--VV--------------A--------------------SID---------------------------S--------------GVRY-T------H-------------E---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RATFRGTKKDGTV--DFDYSFWFTPGTDMSKE-TPDT-----------------------------------------------------------------------------------A---D---E---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------MGTAV----G------------------------------------D------------KGV----------------------GV--APD-A--TWITA---RA---FDIW----------G-AA--N------------KSD-------------------------------------F--------LLA--------------A-----------QW---VL-------CPTKRDGT---GAD-----C------T----------LGA--DV-----------------------------------------ITNSFG-----VDR-STPVYPQ--------------------WT--------------------------WLSK-----VIDT---------WRAA----GV-----Y--------------------------------------------------------------------------------------P---------------VFASG-NT--------NGFL-----------CG---SVYY---------------------------------------------------------------------------------------------------------------------------------------P-GSHE-D---------------------------T---IA---VG--A------------------------------L------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-------------------------------------------------------------------------------------GG-------S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SL-WGA-----S--G--------K-GPS-LETALASSSRDKYVIKP------------------------------------------------------D-----F------V-----------------A-----P-------------G-----------------VG--------------------------------I------------------------------------------------------------------RS---------------------------------------------------------------------------------------------------TMSVKDN-------------------AY-TR----------------LTG------TSMATPHIA----G---------------------------A------------------IA-L----LL----SLYNSSEENSPSY---------------------------------------------------------------------------------------------------------EKVL-------QSL-------------------------TDTTT----------------------------------------------------------RKLHKPFLVPSECGNTSYQEYPNNIYGWGLVN-------------- 589
 590 -----------------------------GVEWNVDQIDAPKAW--------ALG-YDGT--------------------------G-T--VV--------------A--------------------SID---------------------------T--------------GVEW-N------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYHPENPDEPDHEMN-WYDA--VAGEA-SP-------------------------------------------------------------------------------------Y---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TH-V-----------------------TGTMV----GSEPD-------------------------------GT------------NQI----------------------GV--APD-A--KWIAV---KA---F-SE----------D-GG--T------------DAD-------------------------------------I--------LEA--------------G-----------EW---VL-------APKDAEGNP----H-----P------E----------MAP--DV-----------------------------------------VNNSWG-----GGS-GLD-------------------------E--------------------------WYRD-----MVNA---------WRAA----DI-----F--------------------------------------------------------------------------------------P---------------EFSAG-NT--------DLFI----PG----GPG---SIAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------S---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------IN-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-ADF-----S--L--------Q-GPS-P-Y-------D--EIKP------------------------------------------------------E-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------RS-SVP----------------------------------------------------------------------------------------------------GQ-------------------TYEDG----------------WNG------TSMAGPHVS----A---------------------------V------------------AA-L----LK----Q-------ADASLS--VDE-----------------------------------------------------------------------------M---------------------EDIL-------TST-------------------------AEPLT------------------------------------------------------------------------DSTFPDSPNNGYGHGLVNA------------- 590
 591 VLPNEKRQLFKSSSPFNMKKAQKAIKATDGVEWNVDQIDAPKAW--------ALG-YDGT--------------------------G-T--VV--------------A--------------------SID---------------------------T--------------GVEW-N------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYNPENPNEPENEMN-WYDA--VAGEA-SP-------------------------------------------------------------------------------------Y---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TH-V-----------------------TGTMV----GSEPD-------------------------------GT------------NQI----------------------GV--APG-A--KWIAV---KA---F-SE----------D-GG--T------------DAD-------------------------------------I--------LEA--------------G-----------EW---VL-------APKDAEGNP----H-----P------E----------MAP--DV-----------------------------------------VNNSWG-----GGS-GLD-------------------------E--------------------------WYRD-----MVNA---------WRAA----DI-----F--------------------------------------------------------------------------------------P---------------EFSAG-NT--------DLFI----PG----GPG---SIAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------S---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------IN-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-ADF-----S--L--------Q-GPS-P-Y-------D--EIKP------------------------------------------------------E-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------RS-SVP----------------------------------------------------------------------------------------------------GQ-------------------TYEDG----------------WDG------TSMAGPHVS----A---------------------------V------------------AA-L----LK----Q-------ANASLS--VDE-----------------------------------------------------------------------------M---------------------EDIL-------TST-------------------------AEPLT------------------------------------------------------------------------DSTFPDSPNNGYGHGLVNAFDAVSAVTDGLGK 591
 592 -----------------------------GVEWNIDQIDAPKAW--------ELG-YDGT--------------------------G-T--VV--------------A--------------------SID---------------------------T--------------GVEW-N------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYNPENPDEPNNEMN-WYDA--VAGEA-SP-------------------------------------------------------------------------------------Y---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TH-V-----------------------TGTMV----GSEPD-------------------------------GT------------NQI----------------------GV--APG-A--KWIAV---KA---F-SE----------E-GG--T------------DAD-------------------------------------I--------LEA--------------G-----------EW---VL-------APKDAEGNP----H-----P------E----------MAP--DV-----------------------------------------VNNSWG-----GGS-GLD-------------------------E--------------------------WYRD-----MVNA---------WRAA----DI-----F--------------------------------------------------------------------------------------P---------------EFSAG-NT--------DLFI----PG----GPG---SIAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------S---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------IN-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-ADF-----S--L--------Q-GPS-P-Y-------D--EIKP------------------------------------------------------E-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------RS-SVP----------------------------------------------------------------------------------------------------GQ-------------------TYEDG----------------WNG------TSMAGPHVS----A---------------------------V------------------AA-L----LK----Q-------ADASLS--VDE-----------------------------------------------------------------------------M---------------------EDIL-------TST-------------------------AEPLT------------------------------------------------------------------------DSTFPDSPNNGYGHGLVNA------------- 592
 593 ------------------------------VEWNIDQIDAPKAW--------DLG-YDGT--------------------------G-T--VV--------------G--------------------SID---------------------------T--------------GVEW-D------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYNPENPENPDHEMN-WFDA--VSEEA-AP-------------------------------------------------------------------------------------F---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------QHG-------TH-V-----------------------TGTMV----GSEPD-------------------------------GS------------NQI----------------------GV--APG-A--KWIAA---KA---F-SE----------D-GG--T------------DAD-------------------------------------I--------LEA--------------G-----------EW---ML-------APKDADGNP----H-----P------E----------MAP--DV-----------------------------------------VNNSWG-----GGP-GLD-------------------------E--------------------------WYRD-----MVNA---------WIAA----DI-----F--------------------------------------------------------------------------------------P---------------EFSAG-NT--------DLFN----PG----GPE---SIAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------A---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------IN-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-AEF-----S--L--------Q-GPS-P-Y-------D--EVKP------------------------------------------------------E-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------RS-SVP----------------------------------------------------------------------------------------------------GQ-------------------TYEGG----------------WNG------TSMAGPHVS----A---------------------------V------------------VA-L----LR----Q-------ADASIS--VDE-----------------------------------------------------------------------------I---------------------EEVL-------TST-------------------------AETLT------------------------------------------------------------------------DSAFPDSPNNGYGHGLVNA------------- 593
 594 ------------------------------IEWNISQIDAPKAW--------ASG-YDGT--------------------------G-T--VV--------------A--------------------SID---------------------------T--------------GVQW-D------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYDPKNPAVPNHEMN-WYDA--VAKKD-AP-------------------------------------------------------------------------------------Y---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TH-V-----------------------TGTMT----GSEPD-------------------------------GS------------NQI----------------------GV--APG-A--KWIAV---KA---F-SD----------D-GG--T------------DAD-------------------------------------I--------LDA--------------G-----------EW---VL-------APKDKNGTP----H-----P------E----------MAP--DV-----------------------------------------VNNSWA-----GGS-GID-------------------------E--------------------------WYRD-----MVNA---------WRAA----GI-----F--------------------------------------------------------------------------------------P---------------EFSAG-NV--------DLFT----PG----GPG---SIAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------A---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------SQ-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KL-ADF-----S--L--------Q-GPS-P-Y-------H--ETKP------------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------RS-SIP----------------------------------------------------------------------------------------------------GG-------------------TYEGG----------------WNG------TSMAGPHVA----A---------------------------T------------------AA-L----LR----Q-------ANASIT--VDE-----------------------------------------------------------------------------M---------------------EDVL-------TRT-------------------------AEKLT------------------------------------------------------------------------DSDFPESPNNGYGHGLVNA------------- 594
 595 -------------------------SNLANVEWNVERVGAPALW--------EKG-INGT--------------------------G-V--VV--------------A--------------------SID---------------------------S--------------GVQW-D------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYNAATGEV-NHDFN-WFDA--TAGRS-VP-------------------------------------------------------------------------------------Y---D---D---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TH-V-----------------------TGTMV----GSEPD-------------------------------GS------------NKI----------------------GI--APG-A--KWIAV---KA---F-SE----------T-SG--S------------DAN-------------------------------------L--------LAA--------------A-----------EW---IL-------APTDSKGNT----R-----V------D----------MAP--DV-----------------------------------------VNNSWG-----GGP-GLD-------------------------E--------------------------WYRD-----VVKE---------WRNA----GI-----F--------------------------------------------------------------------------------------P---------------TFSAG-NT--------SMTN----NG----GPG---SVAN---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------A---FA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------SN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IV-GDF-----S--L--------R-GPS-P-Y-------G--EIKP------------------------------------------------------D-----I------S-----------------A-----P-------------G-----------------AN--------------------------------I------------------------------------------------------------------RS-SIP----------------------------------------------------------------------------------------------------RS-------------------DYEGG----------------WDG------TSMAAPAIS----A---------------------------I------------------VA-L----LY----E-------VDASLS--VDK-----------------------------------------------------------------------------I---------------------EEIL-------IKT-------------------------ATPLI------------------------------------------------------------------------DKEYPESPNDGYGYGLVNAYNAV--------- 595
 596 ---------------------------AQNIEWNIDRVGAPEAW--------SSG-FDGT--------------------------G-V--VV--------------A--------------------TID---------------------------S--------------GVDW-K------H-------------P---------A--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KEKYRGYNAETGKV-NHQYS-WFDA--VNDKNKVP-------------------------------------------------------------------------------------Y---D---P---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------TGTIV----GSEPN-------------------------------GT------------NQI----------------------GV--APG-A--KWIGV---KA---FGDD----------G-SA--T------------DAD-------------------------------------L--------LEA--------------A-----------QW---IL-------TPTDDAGNE----R-----P------D----------LAP--DI-----------------------------------------VNNSWG-----GGK-DLD-------------------------E--------------------------WYRD-----VVKA---------WKAA----GI-----F--------------------------------------------------------------------------------------P---------------VFAAG-NT--------TWDN----LG----GPG---SVNI---------------------------------------------------------------------------------------------------------------------------------------P-ANYP-E---------------------------S---FA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------QN-------N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RL-ATF-----S--L--------L-GPS-P-Y-------K--EIKP------------------------------------------------------D-----V------T-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------RS-SLP----------------------------------------------------------------------------------------------------GG-------------------RY-GN----------------NEG------TSMAAPAVA----G---------------------------V------------------VA-L----LY----Q-------AAPNLS--IDQ-----------------------------------------------------------------------------I---------------------REIL-------TNT-------------------------AKPLT------------------------------------------------------------------------DKEYPKYPNNGYGYGLVQA------------- 596
 597 ----------------------------------------PEVW--------EQG-INGE--------------------------G-L--VV--------------A--------------------SID---------------------------S--------------GAQW-D------H-------------P---------S--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------INNYRGYNAETGEV-DHSAS-FIDV--VNGET-AA-------------------------------------------------------------------------------------Y---D---D---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------TGTMV----G-YGE-------------------------------GT-------------EI----------------------GV--APG-A--KFIAA---KA---LDST----------N-AG--A------------LDG-------------------------------------I--------LEA--------------A-----------EW---IL-------APGGDAAN------------------------------AP--DI-----------------------------------------VNNSWG-ISGASPE-EVD-------------------------D--------------------------YFRD-----VIVV---------WQNA----DI-----F--------------------------------------------------------------------------------------P---------------VFAAG-ND--------GQTE----EG----------TVGI---------------------------------------------------------------------------------------------------------------------------------------P-ALYP-E---------------------------A---FA---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------RN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AL-AEF-----S--S--------N-GPS-P-Y-------G--ETKP------------------------------------------------------D-----V------S-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------VS-AYP----------------------------------------------------------------------------------------------------GS-------------------EY-AY----------------MSG------TSMAAPAVS----G---------------------------V------------------AA-L----LL----Q-------ANPDAT--VDE-----------------------------------------------------------------------------L---------------------KNVL-------KET-------------------------ATPLT------------------------------------------------------------------------NEVYTEAPNNGFGHGLVDALA----------- 597
 598 LAQPRVIGITISETYAIDEMPTGASPQSTGVRWNIRRIGADRVWN-------ELG-VRGE--------------------------G-V--VV--------------G--------------------SID---------------------------T--------------GAKL-D------H-------------P---------L--------------------------------L--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NANYRGRYPDGSY--DHSYS-WFDP--TGTFPDAP-------------------------------------------------------------------------------------G---D---D---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------IGTMV----G------------------------------------I------------DGI----------------------GV--APG-A--RWIAA---RA---C-SR----------R-AC--Q------------DID-------------------------------------I--------LRA--------------M-----------EW---ML-------APYPSTLGPV-AAN-----P------D----------MRP--QV-----------------------------------------VNNSWG------GP-GGR-------------------------P--------------------------LFQQ-----MVAV---------WRAA----GI-----F--------------------------------------------------------------------------------------P---------------AFAAG-NC--------GQAR----PGCLVTGVG---SVSS---------------------------------------------------------------------------------------------------------------------------------------P-GDYA-E---------------------------S---FA---TG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-------------------------------------------------------------------------------------DN-------D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TL-AAF-----S--S--------Q-GPS-RLT-------S--NVKP------------------------------------------------------D-----L------V-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------ESAALN----------------------------------------------------------------------------------------------------GG-------------------TL--P----------------QNG------TSMASPHTA----G---------------------------A------------------VA-L----LL----S-------LRPGLA--IDQ-----------------------------------------------------------------------------L---------------------EALL-------RTT-------------------------ARDLA----------------------------------------------------------------------------APGPDQQTGYGLLDVYAAAQAARTGLGW 598
 599 ---------------------SESDVEGHESVEIGLRVIKADQLW-------AMG-ITGQ--------------------------GRL--LM-----------------------------------NID---------------------------T--------------GVYP-N------H-------------P---------A--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHKWRGNHVPSNQAWFDPGGGTTTPSDC-----------------------------------------------------------------------------------------D-------------------------G---------------------------------------------------------------------------------------------------------------------------------------------------HG-------SH-T-----------------------MGTMV----GRS------------------------------------------------------------------------LT--TPD-T--VGVAI---------DAEW-IAAKTICS--SP--H------------TSN-------------------------------------S--------VAA--------------F-----------QW---AM-------------NPDGNPST-----I------D----------DMP--DA-----------------------------------------ISNSWYDPDVTNEC-S-GIYKT---------------------------------------------------------TLDA---------VEAA----GI-----A--------------------------------------------------------------------------------------V---------------VFSAG-NN--------GP---------GASTITK---------------------------------------------------------------------------------------------------------------------------------------------P-KNIN-TNEVN-----------------------V---FC---VA--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AALYSG---GNNNP-----I-ASF-----S--S--------R-GPS-TCGGTGSLLIKP-----------------------------------------------------------E-----V------S-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------RS------------------------------------------------------------------------------------------------------------------------SGSATGY-TS----------------LSG------TSMASPHVA----G---------------------------A------------------IA-L----LK----Q-------FAPTLT-----------------------------------------------------------------GQQ--------------I---------------------KFAL-------YNT-------------------------AIDLGSAGE----------------------------------------------------------------------------DNNYGKG----------------- 599
 600 IM-QMEPYTKSIREPALSPLAVNQVFDALPQYALDSEHLNAKAAW-------DAG-FTGR--------------------------G-V--TV--------------G--------------------VID---------------------------D--------------PVDV-S------H-------------P---------D--------------------------------LRA--------------NWAGK---AYDPKADKTY-TTVQSWLDAIDAFGSVPMPVDNQVDENI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TA-V-----------------------TSTIA----AARDG-------------------------------RG------------VV-----------------------GV--APD-A--KYLTAAMFQ--------------------PGSVG------------SAG-------------------------------------V--------AKA--------------I-----------LW---MV---------------------------------D----------NGA--KV-----------------------------------------LNNSWGG-----AG-FDPLIKA---------------------------------------------------------AMDY---------ALER----NV-----T--------------------------------------------------------------------------------------V---------------VVSAG-NESRE--YY-QR-------------------------------------------------------------------------------------------------------------------------------------------------------------P-ALFAGV-------------------------------IP---SA--A------------------------------LAVNNTK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ASF-----S--S--------F-GRH-I----------------------------------------------------------------------S-----V------A-----------------A-----P-------------G-----------------TD--------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------LMASPLFINDDGTRKLGATPPD-GSGY-VL----------------MSG------TSFSGPYTA----A---------------------------T------------------AALI----LG------------AHPELD-----------------------------------------------------------------PYQ--------------V---------------------RRLM-------EET----ADGSVGENPNGF---------------------------------------------------------------------------------------------------------------------- 600
 601 VQRQIEPVRTA--QDQLGAQAVNQVFDTLPQYALDSNHLHAKAAW-------DAG-FTGK--------------------------G-V--KV--------------G--------------------VID---------------------------D--------------PSDV-S------H-------------P---------D--------------------------------LRP--------------NWAGK---AYDPATNTTY-TTVQGWIDAIDGFDG---KVDNKVDPGI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TA-V-----------------------ASTIA----AAKNG-------------------------------QG------------IV-----------------------GV--APD-S--KFYTAAIFQ--------------------PGFIG------------DYL-------------------------------------V--------ARS--------------V-----------IW---TV---------------------------------N----------QGA--QV-----------------------------------------INNSWGG-----TG-YSPLLKQ---------------------------------------------------------AFDY---------ALER----DI-----T--------------------------------------------------------------------------------------V---------------VVSAG-NSYRE--EW-RN-------------------------------------------------------------------------------------------------------------------------------------------------------------P-AQLPGV-------------------------------IA---SA--A------------------------------LDINNDK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGF-----S--T--------Y-GRH-V----------------------------------------------------------------------S-----V------A-----------------A-----P-------------G-----------------VD--------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------MLASPLFINADGTRKTGGYTKDGGSGY-QL----------------ISG------TSFSGPYTS----G---------------------------V------------------AAVI----LG------------AKPDLD-----------------------------------------------------------------PHQ--------------V---------------------RRLM-------EET----ADGSVGSNKAGF---------------------------------------------------------------------------------------------------------------------- 601
 602 ----------------------DQIFDQLPQYALDPRHLNARPAW-------DRG-FFGE--------------------------G-V--TV--------------A--------------------IID---------------------------D--------------PADV-T------H-------------P---------D--------------------------------LAA--------------NWAGL---AYDPVTNTTY-TQASTWTAFIQGLGA----------SNI--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TF-V-----------------------ASTVS----AAKDG-------------------------------QG------------IV-----------------------GL--APR-T--KFLPVAIFQ--------------------PNYVG------------DFY-------------------------------------T--------ARG--------------I-----------VW---AV---------------------------------N----------NGA--QI-----------------------------------------LNNSWGG-----LG-YGNLVKE---------------------------------------------------------AFDY---------ALTN----GV-----V--------------------------------------------------------------------------------------V---------------VASAG-NSYKD--EV-RT-------------------------------------------------------------------------------------------------------------------------------------------------------------P-AGYPGI-------------------------------IA---SA--A------------------------------ADGNRNK-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TNF-----S--T--------Y-GRH-I----------------------------------------------------------------------S-----S------A-----------------A-----P-------------G-----------------LD--------------------------------V------------------------------------------------------------------------------------------------------------------------------------------------------------------------LLANPTWL---------------GGGY-GL----------------ISG------TSFSGPYTA----A---------------------------A------------------AALV----KG------------ACPGAT-----------------------------------------------------------------PYQ--------------V---------------------RRAL-------ETT-------------------------------------------------------------------------------------------------------------------------------------- 602
 603 ----------------------------------------------------------EK--------------------------D-V--II--------------G--------------------MVD---------------------------S--------------GVWP-E------S-------------E---------S--------------------------------F-S--------------DS---G--L-P-PPPAKW-K--G-------------------------------------------------------VCSS--NFTA-------C------------------------------------------------------------------------------------------------------NNKIIGARAY-------------KDGVT------TLS------------PR-----------------------------------------------------------------------------------------D---D---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GRAVP-------------------------------GA------------SM--G-GFA------G-GTA----RSA--VPG-A--RLAIY---KV---CWGD----------D-GC--S------------TAD-------------------------------------I--------LMA--------------F-----------DD---AV--------------------A-----D------G----------V----DV-----------------------------------------LSASVG--S--DFP-AD---YA--------------------DD--------------------------LM-------AVGAFH-------AMRR----GV-----V--------------------------------------------------------------------------------------T---------------SVAAG-ND--------GP---------R----LGAVTNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---HS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TD-------R-RIVSDLVLLG-HGK----TIS-------------GSSINVFPGIGGRSVLIDPGACGQRELKGKNY-----------------------------------------------KG-----------AILLC--GGQSLNEESVHATGADGAIQFRHNTDTAFSFAVPAVRVTKSQYEEIMDY-YNSTRL----ALVSIRNSQA----------RFDAT-----AP------RV-GFF-----S--S--------R-GP--N--------------------MI------TPGIL---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------E-SMS---VSGS--AVDD-RQ----LSY-NI----------------ISG------TSMACPHVT----G---------------------------A------------------AA-Y----VK----S-------VHPDWS-----------------------------------------------------------------PAA--------------V---------------------MSAL-------ITT------------------------ATP---MSAS-----------------------------------------------------STPE------------------AELAYGAGQVN---PLHA------- 603
 604 ----------------------------------------------------------ES--------------------------D-V--II--------------A--------------------VFD---------------------------S--------------GIWP-E------S-------------E---------S--------------------------------F-N--------------DK---G--F-G-PPPSKW-K--G-------------------------------------------------------TCQTSKNFT--------C------------------------------------------------------------------------------------------------------NNKIIGAKIY--------------KVDGFFSKDDPKS------------VR-----------------------------------------------------------------------------------------D---I---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTAA----GNPVS-------------------------------TA------------SM--L-GLG------Q-GTS----RGG--VTK-A--RIAVY---KV---CWFD------------GC--T------------DAD-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----DI-----------------------------------------ITVSLG----GFSD-EN---YF--------------------RD--------------------------GI-------AIGAFH-------AVRN----GV-----L--------------------------------------------------------------------------------------T---------------VTSAG-NS--------GP---------R----PSSLSNFS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------S---IS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-KFVTK-VELG-NKI----TYE-------------GTSINTF------------------DLKGELYPIIYGGDAPN----KGEGIDGSSSRYCSSGSLDKKL-VKGKIVLCESRS-----------KALGPFDAGAVGALIQGQGF-----------RDLPPSLPLPGSYLALQDGASVYDY-INSTRT----PIATIFKTDE----------TKDTI-----AP------VV-ASF-----S--S--------R-GP--N--------------------IV------TPEIL---K--------------------P------------D-----L------V-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-SWS-----------------------------------------------------------------------------------------------P-ASP---PSDV--EGDN-RT----LNF-NI----------------ISG------TSMACPHVS----G---------------------------A------------------AA-Y----VK----S-------FHPTWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------MTT------------------------AKQ---LSPK-----------------------------------------------------T------------------HLRAEFAYGAGQID---PSKAV------ 604
 605 --------------------------------------------------------QVES--------------------------N-I--VV--------------G--------------------VLD---------------------------T--------------GIWP-E------S-------------P---------S--------------------------------F-D--------------DE---G--F-S-PPPPKW-K--G-------------------------------------------------------TCETSNNFR--------C------------------------------------------------------------------------------------------------------NRKIIGARSY-------------HIGRPISPGD-VNG------------PR-----------------------------------------------------------------------------------------D---T---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GGLVS-------------------------------QA------------NL--Y-GLG------L-GTA----RGG--VPL-A--RIAAY---KV---CWN-----------D-GC--S------------DTD-------------------------------------I--------LAA--------------Y-----------DD---AI--------------------A-----D------G----------V----DI-----------------------------------------ISLSVG--G--ANP-RH---YF--------------------VD--------------------------AI-------AIGSFH-------AVER----GI-----L--------------------------------------------------------------------------------------T---------------SNSAG-NG--------GP---------N----FFTTASLS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-KFVTQ-VQIG-NGQ----SFQ-------------GVSINTF------------------D--NQYYPLVSGRDIPN----------------TGFDKSTSRFCTDKSVNPNLLKG-----------KIVVCEASFGPHE-FFKSLDGAAGVLMTSNTRDYADSYPLPSSVLDPNDLLATLRY-IYSIRS----PGATIFKSTT----------ILNAS-----AP------VV-VSF-----S--S--------R-GP--N--------------------RA------TKDVI---K--------------------P------------D-----I------S-----------------G-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AW------------------------------------------------------------------------------------------------P-SVA---PVGG----IR-RN----TLF-NI----------------ISG------TSMSCPHIT----G---------------------------I------------------AT-Y----VK----T-------YNPTWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT------------------------ASP---MNAR-----------------------------------------------------FNPQ------------------AEFAYGSGHVN---PLKAVR----- 605
 606 --------------------------------------------------------GIES--------------------------N-I--IV--------------G--------------------VLD---------------------------T--------------GIDV-E------S-------------P---------S--------------------------------F-N--------------DK---G--V-G-PPPAKW-K--G-------------------------------------------------------KCVTGNNFTR-------C------------------------------------------------------------------------------------------------------NNKVIGAKYF-------------HIQSEGLPDGEGDT------------AA-----------------------------------------------------------------------------------------D---H---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTIA----GVSVS-------------------------------SA------------SL--F-GIA------N-GTA----RGG--VPS-A--RIAAY---KV---CWD-----------S-GC--T------------DMD-------------------------------------M--------LAA--------------F-----------DE---AI--------------------S-----D------G----------V----DI-----------------------------------------ISISIG--G--ASL-P----FF--------------------ED--------------------------PI-------AIGAFH-------AMKR----GI-----L--------------------------------------------------------------------------------------T---------------TCSAG-NN--------GP---------G----LFTVSNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---MT---VA--A------------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------LD-------R-KFETV-VKLG-NGL----TAS-------------GISLNGF------------------NPRKKMYPLTSGSLASNLSAGGYGEPSTCEPGTLGEDKVMGKVVYCEAGREEGGNG-----------GQGQD-------H-VVRSLKGAGVIVQLLEPTDMATSTLIAGSYVFFEDGTKITEY-INSTKN----PQAVIFKT-K----------TTKML-----AP------SI-SSF-----S--A--------R-GP--Q--------------------RI------SPNIL---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------K-LAS---VTGY--PDDN-RR----TLF-SI----------------MSG------TSMACPHAA----A---------------------------A------------------AA-Y----VK----S-------FHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT------------------------ATP---MRIK-----------------------------------------------------GN-E------------------AELSYGSGQIN---PRRAIH----- 606
 607 --------------------------------------------------------KAER--------------------------D-V--II--------------G--------------------VLD---------------------------T--------------GITP-D------S-------------E---------S--------------------------------F-L--------------DH---G--L-G-PPPAKW-K--G-------------------------------------------------------SCGPYKNFTG-------C------------------------------------------------------------------------------------------------------NNKIIGAKYF-------------K-HDGNVPAGEVRS------------PI-----------------------------------------------------------------------------------------D---I---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTVA----GVLVA-------------------------------NA------------SL--Y-GIA------N-GTA----RGA--VPS-A--RLAMY---KV---CWAR----------S-GC--A------------DMD-------------------------------------I--------LAG--------------F-----------EA---AI--------------------H-----D------G----------V----EI-----------------------------------------ISISIG--G--P-I-AD---YS--------------------SD--------------------------SI-------SVGSFH-------AMRK----GI-----L--------------------------------------------------------------------------------------T---------------VASAG-ND--------GP---------S----SGTVTNHE---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------ID-------R-TFKSK-IDLG-NGK----SFS-------------GMGISMF------------------SPKAKSYPLVSGVDAAK----------------NTDDKYLARYCFSDSLDRKKVKG-----------KVMVCRMGGGGVESTIKSYGGAGAIIVSDQYLDNAQIFMAPATSVNSSVGDIIYRY-INSTRS----ASAVIQKTRQ----------V-TIP-----AP------FV-ASF-----S--S--------R-GP--N--------------------PG------SIRLL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------ID--------------------------------I------------------------------------------------------------------LA-AFT-----------------------------------------------------------------------------------------------L-KRS---LTGL--DGDT-QF----SKF-TI----------------LSG------TSMACPHVA----G---------------------------V------------------AA-Y----VK----S-------FHPDWT-----------------------------------------------------------------PAA--------------I---------------------KSAI-------ITS------------------------AKP---ISRR-----------------------------------------------------VNKD------------------AEFAYGGGQIN---PRRAAS----- 607
 608 --------------------------------------------------------AIES--------------------------D-T--II--------------G--------------------FID---------------------------S--------------GIWP-E------S-------------E---------S--------------------------------F-S--------------DK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCSGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------SEG------------TR-----------------------------------------------------------------------------------------D---L---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNAVA-------------------------------DA------------SF--F-GIG------N-GTA----RGG--VPA-S--RIAAY---KV---CSE-----------K-DC--T------------AAS-------------------------------------L--------LSA--------------F-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ISISLA--S--EFP-QK---YY--------------------KD--------------------------AI-------AIGAFH-------ANVK----GI-----L--------------------------------------------------------------------------------------T---------------VNSAG-NS--------GS---------F----PSTTASVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------TN-------R-GFFTK-VVLG-NGK----TLV-------------GRSVNSF------------------DLKGKKYP----------------------------------LVYGDNFNESLVQG-----------KILVS-------K-FPTSSKVAVGSILIDDYQHYALLSSKPFSLLPPDDFDSLVSY-INSTRS----PQGTFLKTEA----------FFNQT-----AP------TV-ASF-----S--S--------R-GP--N--------------------FI------AVDLL---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-LGS---PSEE--ESDK-RR----VKY-SV----------------MSG------TSMSCPHVA----G---------------------------V------------------AA-Y----IR----T-------FHPKWS-----------------------------------------------------------------PSV--------------I---------------------QSAI-------MTT------------------------AWP---MKPN-----------------------------------------------------RPGF---------------AS-TEFAYGAGHVD---QIAAIN----- 608
 609 --------------------------------------------------------AIES--------------------------D-T--II--------------G--------------------FID---------------------------S--------------GIWP-E------S-------------E---------S--------------------------------F-S--------------DK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCSAGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------NEG------------TR-----------------------------------------------------------------------------------------D---I---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNAVK-------------------------------NT------------SF--Y-GIG------N-GTA----RGG--VPA-S--RIAAY---KA---CSE-----------M-GC--T------------TES-------------------------------------V--------LSA--------------F-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ISISLG--A--NLV-RT---YE--------------------TD--------------------------PI-------AIGAFH-------AMVK----GI-----L--------------------------------------------------------------------------------------T---------------VQSAG-NG--------GP---------N----PGSVMSVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------TN-------R-GFVTK-VVLG-NGK----TFV-------------GKSLNAF------------------DLKGKNYP----------------------------------L-YGGSTDGPLLRG-----------KILVS-------E-DKVSSEIVVANI-NENYHDYAYVSILPSSALSKDDFDSVISY-VNSTKS----PHGTVLKSEA----------IFNQA-----AP------KV-AGF-----S--S--------R-GP--N--------------------TI------AVDIL---K--------------------P------------D-----V------T-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AFS-----------------------------------------------------------------------------------------------P-LNS---PAQD--KRDN-RH----VKY-SV----------------LSG------TSMSCPHVA----G---------------------------V------------------AA-Y----IK----T-------FHPEWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---MNAT-----------------------------------------------------GTAV---------------AS-TEFAYGAGHVD---PIAAIN----- 609
 610 --------------------------------------------------------AVES--------------------------D-T--II--------------G--------------------FID---------------------------S--------------GIWP-E------S-------------E---------S--------------------------------F-S--------------DK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCKGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------SEG------------TR-----------------------------------------------------------------------------------------D---L---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------TSTAA----GNAVA-------------------------------DT------------SF--F-GIG------N-GTA----RGG--VPA-S--RVAAY---KV---CTI-----------T-GC--S------------DDN-------------------------------------V--------LSA--------------F-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ISVSLG--G--DYP-SL---YA--------------------ED--------------------------TI-------AIGAFH-------AMAK----GI-----L--------------------------------------------------------------------------------------T---------------VHSAG-NA--------GP---------N----PTTVVSVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TN-------R-RFLTK-VVLG-NGK----TLV-------------GKSVNAF------------------DLKGKKYP----------------------------------LEYGDYLNESLVKG-----------KILVS-------R-YLSGSEVAVSFI-TTDNKDYASISSRPLSVLSQDDFDSLVSY-INSTRS----PQGSVLKTEA----------IFNQL-----SP------KV-ASF-----S--S--------R-GP--N--------------------TI------AVDIL---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-LSL---PSED--RRDK-RR----VKY-SV----------------LSG------TSMACPHVT----G---------------------------V------------------AA-Y----IK----T-------FHPDWS-----------------------------------------------------------------PSV--------------I---------------------QSAI-------MTT------------------------AWQ---MNAT-----------------------------------------------------GTGA---------------ES-TEFAYGAGHVD---PIAAIN----- 610
 611 --------------------------------------------------------TVES--------------------------D-T--II--------------G--------------------VID---------------------------S--------------GITP-E------S-------------Q---------S--------------------------------F-S--------------DK---G--F-G-PPPQKW-K--G-------------------------------------------------------VCSGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------SEG------------TR-----------------------------------------------------------------------------------------D---M---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNAVV-------------------------------DA------------SF--F-GIG------N-GTV----RGG--VPA-S--RVAAY---KV---CTP-----------T-GC--S------------SEA-------------------------------------L--------LSA--------------F-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ITISIG--D--KTA-SM---FQ--------------------ND--------------------------PI-------AIGAFH-------AMAK----GV-----L--------------------------------------------------------------------------------------T---------------VNSAG-NS--------GP---------K----PISVSGVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TN-------R-GFVTK-VVLG-NGK----TLV-------------GKSVNAY------------------E-----------------------------------------------------------------------------------------------------------------------------STDS----PQAIVLKTEA----------IFNRT-----SP------VI-ASF-----S--S--------R-GP--N--------------------TI------AVDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-AGE---PSQD----DT-RH----VKY-SV----------------LSG------TSMSCPHVA----G---------------------------V------------------AA-Y----VK----T-------FNPKWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---VNAT-----------------------------------------------------GTGI---------------AS-TEFAYGSGHVD---PIAASN----- 611
 612 --------------------------------------------------------AIES--------------------------D-T--II--------------G--------------------VID---------------------------T--------------GIWP-E------S-------------K---------S--------------------------------F-S--------------DK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCSGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------SEG------------TR-----------------------------------------------------------------------------------------D---T---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNAVK-------------------------------DT------------SF--F-GIG------N-GTV----RGG--VPA-S--RIAAY---KV---CTD-----------S-GC--S------------SEA-------------------------------------L--------LSS--------------F-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ITISIG--F--QFP-SI---FE--------------------DD--------------------------PI-------AIGAFH-------AMAK----GI-----L--------------------------------------------------------------------------------------T---------------VSSAG-NS--------GP---------K----PTTVSHVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---FT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TN-------R-GFITK-VVLG-NGK----TLA-------------GRSVNAF------------------E-----------------------------------------------------------------------------------------------------------------------------SQDS----PQAAVLKTET----------IFNRT-----SP------VI-ASF-----S--S--------R-GP--N--------------------TI------AVDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AFS-----------------------------------------------------------------------------------------------P-NGE---PSED----DT-RR----VKY-SV----------------FSG------TSMACPHVA----G---------------------------V------------------AA-Y----VK----T-------FYPRWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---VKAK-----------------------------------------------------GRGI---------------AS-TEFAYGAGHVD---PMAALN----- 612
 613 --------------------------------------------------------AVES--------------------------D-T--IV--------------G--------------------VFD---------------------------T--------------GISP-E------S-------------E---------S--------------------------------F-S--------------GK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCKGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARDY-------------T----------NEG------------TR-----------------------------------------------------------------------------------------D---I---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNVVE-------------------------------NT------------SF--Y-GIG------N-GTA----RGG--VPD-S--RIAAY---KV---CSG-----------A-GC--S------------SEY-------------------------------------I--------LSA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------ISASLG--G--DTA-YM---YE--------------------KD--------------------------PI-------AIGAFH-------AMAK----GI-----L--------------------------------------------------------------------------------------T---------------VQSAG-NN--------GP---------N----PT--VSVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TN-------R-RIVTK-VVLG-NGK----TLV-------------GQSVNAF------------------DLKGKQYP----------------------------------LVYETSVEK--------------------C-------N-NESLTTLALSFLTLTPQSNEQIISM----------FHTLIMW------S----PKATILKSEA----------IFNQT-----DP------KV-AGF-----S--S--------R-GP--N--------------------TI------AVDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-LVS---PSAT--TLDN-RR----VNY-TI----------------TSG------TSMACPHVS----G---------------------------V------------------AA-Y----IK----T-------FHPEWY-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---MNPS-----------------------------------------------------GTDA---------------VS-TEFAYGSGHID---PIAAIN----- 613
 614 --------------------------------------------------------LIES--------------------------D-T--II--------------G--------------------VID---------------------------S--------------GIYP-E------S-------------D---------S--------------------------------F-S--------------GK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCKGGTNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARYY-------------TPKL----EGFPES------------AR-----------------------------------------------------------------------------------------D---N---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASIAA----GNAVK-------------------------------HV------------SF--Y-GLG------N-GTV----RGG--VPA-A--RIAVY---KV---CDPG---------VI-RC--T------------SDG-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------K----------V----DI-----------------------------------------ITVSLG--A--DAV-GT---FE--------------------ED--------------------------TL-------AIGAFH-------AMAK----GI-----L--------------------------------------------------------------------------------------T---------------VNGAG-NN--------GP---------E----RRTIVSMA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---FT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------MN-------R-AFITK-VVLG-NGK----TIV-------------GRSVNSF-----------------------------------------------------------------------------------------------------------------------------------------------NSTKN----PKAAVLKSET----------IFNQK-----AP------VV-ASY-----S--S--------R-GP--N--------------------PL------IHDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------SE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-YVP---PSES----DT-RH----VKY-TV----------------ISG------TSMSCPHVA----G---------------------------V------------------AA-Y----IK----T-------FHPLWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---MNAS-----------------------------------------------------TSPS---------------NELAEFAYGAGHVD---PIAAIH----- 614
 615 --------------------------------------------------------IIES--------------------------D-T--II--------------G--------------------VID---------------------------S--------------GIYP-E------S-------------D---------S--------------------------------F-S--------------GK---G--F-G-PPPKKW-K--G-------------------------------------------------------VCKGGKNFT--------W------------------------------------------------------------------------------------------------------NNKLIGARYY-------------TPKL----EGFPES------------AR-----------------------------------------------------------------------------------------D---Y---------------------M--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASTAA----GNAVK-------------------------------HV------------SF--Y-GLG------N-GTA----RGG--VPA-A--RIAVY---KV---CDPG---------VD-GC--T------------TDG-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------K----------V----DI-----------------------------------------ITISIG--G--DNS-SP---FE--------------------ED--------------------------PI-------AIGAFH-------AMAK----GI-----L--------------------------------------------------------------------------------------I---------------VNSAG-NS--------GP---------E----PSTVASIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---FT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------TN-------R-AFVTK-VVLG-NGK----TVV-------------GRSVNS------------------------------------------------------------------------------------------------------------------------------------------------NSTKN----PKAAVLKSET----------IFNQR-----AP------VV-ASY-----F--S--------R-GP--N--------------------TI------IPDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------SE--------------------------------I------------------------------------------------------------------VA-AYS-----------------------------------------------------------------------------------------------P-DAP---PSIS----DT-RR----VKY-SV----------------DTG------TSMSCPHVA----G---------------------------V------------------AA-Y----LK----S-------FHPRWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---MNAS-----------------------------------------------------TSPF---------------NELAEFAYGAGHVD---PITAIH----- 615
 616 --------------------------------------------------------SIES--------------------------D-T--II--------------G--------------------VID---------------------------S--------------GIYP-E------S-------------D---------S--------------------------------F-S--------------DQ---G--F-G-PPPKKW-K--G-------------------------------------------------------TCAGGKNFT--------C------------------------------------------------------------------------------------------------------NNKVIGARDY-------------TAKS----KA-NQT------------AR-----------------------------------------------------------------------------------------D---Y---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAA----GNAVA-------------------------------NS------------NF--Y-GLG------N-GTA----RGG--VPA-A--RIAVY---KV---CDN-----------E-GC--D------------GEA-------------------------------------M--------MSA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------ISISIV--L--DNI-PP---FE--------------------ED--------------------------PI-------AIGAFH-------AMAV----GV-----L--------------------------------------------------------------------------------------T---------------VNAAG-NN--------GP---------K----ISTVTSTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---FS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V-------------------------------------------------------------------------------------TN-------R-AFMAK-VVLG-DGK----ILI-------------GRSVNTY------------------D---------------------------------------------------------------------------------------------------------------------------MNSTKN----PKATVLKSEE----------ISNQR-----AP------LV-ASF-----S--S--------R-GP--S--------------------SI------VSDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VE--------------------------------I------------------------------------------------------------------LA-AYS-----------------------------------------------------------------------------------------------P-DSS---PTES--EFDT-RR----VKY-SV----------------LSG------TSMACPHVA----G---------------------------V------------------AA-Y----VK----T-------FHPQWS-----------------------------------------------------------------PSM--------------I---------------------QSAI-------MTT------------------------AWP---MNAS-----------------------------------------------------GSGF---------------VS-TEFAYGSGHVD---PIDAIN----- 616
 617 --------------------------------------------------------SVES--------------------------D-T--II--------------G--------------------VFD---------------------------G--------------GIWP-E------S-------------E---------S--------------------------------F-S--------------DK---G--F-G-PPPKKW-K--G-------------------------------------------------------ICAGGKNFT--------C------------------------------------------------------------------------------------------------------NNKLIGARHY-------------S----------PGD------------AR-----------------------------------------------------------------------------------------D---S---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAA----GNAVA-------------------------------NT------------SF--F-GIG------N-GTV----RGA--VPA-S--RIAVY---RV---CAG-----------E--C--R------------DDA-------------------------------------I--------LSA--------------F-----------DD---AI--------------------S-----D------G----------V----DI-----------------------------------------ITISIG--D--INV-YP---FE--------------------KD--------------------------PI-------AIGAFH-------AMSK----GI-----L--------------------------------------------------------------------------------------T---------------VNAAG-NT--------GP---------D----TASITSLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------AN-------R-EFVSK-VVLG-DGK----TLV-------------K------------------------------------------------------------------------------------------------------------------------------------------------------SEKS----PEAAVLKSES----------IFYQT-----AP------KI-LSF-----S--S--------R-GP--N--------------------II------VADIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------LE--------------------------------I------------------------------------------------------------------LA-ANS-----------------------------------------------------------------------------------------------L-RAS---PFY-----DT-AY----VKY-SV----------------ESG------TSMSCPHAA----G---------------------------V------------------AA-Y----VK----T-------FHPQWS-----------------------------------------------------------------PSM--------------I---------------------KSAI-------MTT------------------------AWS---MNAS-----------------------------------------------------QSGY---------------AS-TEFAYGAGHVD---PIAATN----- 617
 618 --------------------------------------------------------VKES--------------------------D-V--IV--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------E---------S--------------------------------F-D--------------DE---G--F-G-PPPKKW-K--G-------------------------------------------------------SCKGGLKFA--------C------------------------------------------------------------------------------------------------------NNKLIGARFY---------------------NKFADS------------AR-----------------------------------------------------------------------------------------D---E---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNAVQ-------------------------------AA------------SF--Y-GLA------Q-GTA----RGG--VPS-A--RIAAY---KV---CFN-----------R--C--N------------DVD-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------ISISIS--A--DYV-SN---LL--------------------NA--------------------------SV-------AIGSFH-------AMMR----GI-----I--------------------------------------------------------------------------------------T---------------AGSAG-NN--------GP---------D----QGSVANVS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---IT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------TD-------R-QFIDR-VVLG-NGK----ALT-------------GISVNTF------------------NLNESAEP------------------------------------------------------------------------------------------------------------------------------PQAEILRTEE----------IVDRE-----AP------YV-PSF-----S--S--------R-GP--S--------------------FV------IQNLL---K--------------------P------------D-----V------S-----------------A-----P-------------G-----------------LE--------------------------------I------------------------------------------------------------------LA-AFS-----------------------------------------------------------------------------------------------P-VAS---PSSFLNPEDK-RS----VRY-SV----------------MSG------TSMACPHVA----G---------------------------V------------------AA-Y----VK----S-------FHPDWS-----------------------------------------------------------------PSA--------------I---------------------KSAI-------MTT------------------------ATP---MNLK-----------------------------------------------------KNPE------------------QEFAYGSGQIN---PTKASD----- 618
 619 GQVARNVVVQQYNHGFSGFAARLSKEEAAALRRKPGVVSVFPDPV-------Y-----QL--------------------------D-T--II--------------G--------------------LLD---------------------------S--------------GIWP-E------S-------------P---------S--------------------------------F-D--------------DA---G--F-G-PVPARW-K--G-------------------------------------------------------TCMSGDDFNS----SN-C------------------------------------------------------------------------------------------------------NKKLIGARYY-----------DVGEVTRGGGVRRSGS------------AR-----------------------------------------------------------------------------------------D---Q---------------------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GNAVA-------------------------------GA------------SY--Y-GLA------S-GTA----KGG--SAA-S--RLAMY---RV---CSEE------------GC--A------------GSA-------------------------------------I--------LAG--------------F-----------DD---AI--------------------G-----D------G----------V----DV-----------------------------------------ISVSLG--ASPYFS-PD---FS--------------------ED--------------------------PI-------AIGAFH-------AVAK----GV-----T--------------------------------------------------------------------------------------V---------------ACSAG-NA--------GP---------G----SSTVVNAA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---MT---VA--A------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-DFESD-VVLG-GGN--SSAVK-------------GGAINFS-----------------NLDKSPKYPLITGESAKS-----SSVSDNKSASHCEPGTLDAGK-IKGKIVLCHHSQ-----------SDTSKMVKVDELKSGGAVGSILVNDVERSVTTAYL-D--FPVTEVTSAAAANLHKY-IASTSE----PVATITPSIT----------VTEFKP----AP------VV-AYF-----S--S--------R-GP--S--------------------SQ------TGNIL---K--------------------P------------D-----V------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWI-----------------------------------------------------------------------------------------------P-TSS---LPSG--QKQP--S-----QF-NL----------------ISG------TSMSCPHVA----G---------------------------A------------------AA-T----IK----A-------WNPTWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------MTT------------------------ATQ---LNND-----------------------------------------------------KAPMTTDA--------G--SAATPFDYGAGQVN---PSGAL------ 619
 620 -----------------------------------------------------SE-MHEG--------------------------D-T--II--------------G--------------------FLD---------------------------S--------------GIWP-E------A-------------Q---------S--------------------------------F-N--------------DR---H--M-G-PVPEKW-K--G-------------------------------------------------------TCMRGKKTQPD---SFRC------------------------------------------------------------------------------------------------------NRKLIGARYYNSSFFLD---------------PDYET------------PR-----------------------------------------------------------------------------------------D---F---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIAA----GQIIA-------------------------------NA------------SY--Y-GLA------S-GIM----RGG--SPS-S--RIAMY---RA---CSLL------------GC--R------------GSS-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------ISISMG-----LWP-DN---LL--------------------ED--------------------------PL-------SIGSFH-------AVER----GI-----T--------------------------------------------------------------------------------------V---------------VCSVG-NS--------GP---------S----SQSVFNAA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---IT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-GFESN-ILLGGDEN----RLI------------EGFGINIA-----------------NIDKTQAYPLIHARSAKK------IDANEEAARNCAPDTLDQTI-VKGKIVVCDSDL-----------DNQVIQWKSDEVKRLGGIGMVLVDDESMDLSFI---DPSFLVTIIKPEDGIQIMSY-INSTRE----PIATIMPTRS----------RTGHML----AP------SI-PSF-----S--S--------R-GP--Y--------------------LL------TRSIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-SWL-----------------------------------------------------------------------------------------------V------------GDRNAAPEGKPPPLF-NI----------------ESG------TSMSCPHVS----G---------------------------I------------------AA-R----LK----S-------RYPSWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------MTT------------------------AVQ---MTNT-----------------------------------------------------GSHITTETG----------EKATPYDFGAGQVTIFGPSS-------- 620
 621 ------------------------------------------DGS-------Y---------------------------------D-S--IV--------------G--------------------ILD---------------------------T--------------GIWP-E------S-------------E---------S--------------------------------F-N--------------DK---D--M-G-PIPSRW-K--G-------------------------------------------------------TCMEAKDFKS----SN-C------------------------------------------------------------------------------------------------------NRKIIGARYYKNPD-------DDSEYY---------T------------TR-----------------------------------------------------------------------------------------D---V---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-V-----------------------SSTIA----GSAVE-------------------------------NA------------SY--Y-GVA------S-GTA----KGG--SQN-A--RIAMY---KV---CNPG------------GC--T------------GSS-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------LSLSLG--APAYAR-ID---LN--------------------TD--------------------------PI-------AIGAFH-------AVEQ----GI-----L--------------------------------------------------------------------------------------V---------------ICSAG-ND--------GP---------D----GGTVTNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---MT---VA--A------------------------------N------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-DFESD-VVLG-G----NKVIK-------------GEGIHFS-----------------NVSKSPVYPLIHGKSAKS-----ADASEG-SARACDSDSLDQEK-VKGKIVLCENVG-----------GSYYASSARDEVKSKGGTGCVFVDDRTRAVASAYG-S--FPTTVIDSKEAAEIFSY-LNSTKD----PVATILPTAT----------VEKFTP----AP------AV-AYF-----S--S--------R-GP--S--------------------SL------TRSIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-NDS---SISL--EGKP-AS-----QY-NV----------------ISG------TSMAAPHVS----A---------------------------V------------------AS-L----IK----S-------QHPTWG-----------------------------------------------------------------PSA--------------I---------------------RSAI-------MTT------------------------ATQ---TNND-----------------------------------------------------KGLITTET--------G--ATATPYDSGAGELS---STASMQ----- 621
 622 --------------------------------------------------------SSGT--------------------------D-I--IL--------------G--------------------FLD---------------------------T--------------GIWP-E------A-------------A---------S--------------------------------F-S--------------DK---G--M-G-PVPSRW-K--G-------------------------------------------------------ACVKGENFNV----SN-C------------------------------------------------------------------------------------------------------NRKIIGARYYSGGEDDDLK----KNSKPKSIWPESRT------------AR-----------------------------------------------------------------------------------------D---Y---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TY-T-----------------------AATAA----GSFVD-------------------------------NA------------NY--N-GLA------N-GTA----RGG--SAS-SSTRIAMY---RV---CGLD----------Y-GC--P------------GVQ-------------------------------------I--------LAA--------------F-----------DD---AV--------------------K-----D------G----------V----DI-----------------------------------------VSISIG--VRSSNQ-AD---FV--------------------KD--------------------------AI-------AIGAFH-------ATQK----GI-----L--------------------------------------------------------------------------------------V---------------VSSAG-NE--------GP---------D----SQTVVNAA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---FT---VG--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------ID-------R-EFLSN-VVLKSNRN-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PVATITLTEV----------VTNYIP----AP------VI-ASF-----S--S--------R-GP--G--------------------GL------TQNIL---K--------------------P------------D-----I------S-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IA-AWN-----------------------------------------------------------------------------------------------P-------PNQS--DEDTVVSEMTPSTF-NM----------------MSG------TSVAVPHVT----G---------------------------A------------------AA-F----VK----S-------INPTWS-----------------------------------------------------------------SSA--------------I---------------------RSAL-------MTT------------------------AIV---RNNM-----------------------------------------------------GKLLTNESD----------IPGTPFDFGAGVVN---PIGALQ----- 622
 623 ----------------------------------------------------------SA--------------------------D-V--II--------------G--------------------VID---------------------------S--------------GVWP-E------S-------------P---------S--------------------------------F-N--------------DV---G--M-G-AVPARW-R--G-------------------------------------------------------VCMEGPDFNK----TN-C------------------------------------------------------------------------------------------------------NKKLIGARYY------GNEPGGSKATVKPPSTTATDS------------PR-----------------------------------------------------------------------------------------D---T---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------TSTAA----GAAVS-------------------------------GA------------DY--Y-GLG------RAGPA----RGG--APG-S--RVAAY---RA---CILG------------GC--S------------GSA-------------------------------------L--------LKA--------------I-----------DD---AV--------------------S-----D------G----------V----DV-----------------------------------------ISMSVG--VSSAFP-DD---FL--------------------SD--------------------------PI-------AIGAFH-------AHRR----GV-----L--------------------------------------------------------------------------------------V---------------VCSAG-ND--------GP---------V----PYTVVNAA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---VT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-AFQSS-IVLG-NGN----VVK-------------GIGINFS----------------NQSLGGEHYPLVFGAQAVG------RYTPVAEASNCYPGSLDPEK-VRGKIVVCVGST-----------GTMMASRRVKKVVAEGSGASGLVLIDDAKMDEPYD-AGSFAFSQVGSHVGAQILDY-INSTKN----PTAVILPTED----------VNEFKP----AP------TV-ASF-----S--A--------R-GP--G--------------------GL------TESIL---K--------------------P------------D-----L------M-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AWV-----------------------------------------------------------------------------------------------P-PPN---PAVV--PAGK-KP----SAF-AF----------------LSG------TSMACPHVA----G---------------------------A------------------GA-F----LK----S-------AHPGWT-----------------------------------------------------------------PSM--------------I---------------------RSAL-------MTT------------------------ATT---RDNL-----------------------------------------------------GRPVASST--------G--GAATGHDMGAGEIS-------------- 623
 624 --------------------------------------------------------EVES--------------------------N-V--IV--------------G--------------------VID---------------------------G--------------GIWP-E------S-------------K---------S--------------------------------F-S--------------DE---G--I-G-PIPKKW-K--G-------------------------------------------------------TCAGGTNFT--------C------------------------------------------------------------------------------------------------------NRKVIGARHY-----------------------VHDS------------AR-----------------------------------------------------------------------------------------D---S---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------AHG-------SH-T-----------------------ASTAA----GNKVK-------------------------------GV------------SV--N-GVA------E-GTA----RGG--VPL-G--RIAVY---KV---CEPL------------GC--N------------GER-------------------------------------I--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----DV-----------------------------------------LTISLG-----GGV-TK---VD--------------------ID--------------------------PI-------AIGSFH-------AMTK----GI-----V--------------------------------------------------------------------------------------T---------------TVAVG-NA--------GT---------A----LAKADNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---IS---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------TD-------R-KFVTN-VVNG-DDK----MLP-------------GRSINDF------------------DLEGKKYPLAYGKTASN-------NCTEELARGCASGCLNT---VEGKIVVCDVPN-----------NVMEQ-------KAAGAVGTILHVTDVDTPG-----LGPIAVATLDDTNYEELRSY-VLSSPN----PQGTILKTNT----------VKDNG-----AP------VV-PAF-----S--S--------R-GP--N--------------------TL------FSDIL---S--------------------N------------E-----H------S-----------------KRNNR-P-------------M-----------------SQ--------------------------------Y------------------------------------------------------------------IS-SIF-----------------------------------------------------------------------------------------------T-TGSNRVPGQS-------------VDY-YF----------------MTG------TSMACPHVA----G---------------------------V------------------AA-Y----VK----T-------LRPDWS-----------------------------------------------------------------ASA--------------I---------------------KSAI-------MTT------------------------AWA---MNAS-----------------------------------------------------K------------------NAEAEFAYGSGFVN---PTVAVD----- 624
 625 --------------------------------------------------------NMGD--------------------------Q-V--II--------------G--------------------VID---------------------------T--------------GVWP-E------S-------------E---------S--------------------------------F-N--------------DN---G--V-G-PIPRKW-K--G-------------------------------------------------------GCESGENFRS----T-DC------------------------------------------------------------------------------------------------------NRKLIGAKYFINGFLAEN-----KG-FNTTESRDYIS------------AR-----------------------------------------------------------------------------------------D---F---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIAG----GSFVP-------------------------------NV------------SY--K-GLA------G-GTL----RGG--APR-A--RIAMY---KA---CWFHE-E----LKGV-TC--S------------DSD-------------------------------------I--------MKA--------------I-----------DE---AI--------------------H-----D------G----------V----DV-----------------------------------------LSISLV-GQIPLNS-ET---DI--------------------RD--------------------------EF-------ATGLFH-------AVAK----GI-----V--------------------------------------------------------------------------------------V---------------VCAGG-ND--------GP---------A----AQTVVNIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTP-ITLG-NNK----VIL-------------GQATY-------------------------------------------------------------------------------------------------------------------------------------------------RSTRS----PVVKIQRSRT----------LSGQPV----GT------KV-VNF-----S--S--------R-GP--N--------------------SM------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VR--------------------------------I------------------------------------------------------------------LA-ATS-----------------------------------------------------------------------------------------------P------------------NDTLNVGGF-AM----------------LSG------TSMATPVIS----G---------------------------V------------------IA-L----LK----A-------LHPEWS-----------------------------------------------------------------PAA--------------F---------------------RSAI-------VTT------------------------AWR---TDPF-----------------------------------------------------GEQIFAEG--------SSRKVSDPFDYGGGIVN---PEKAAE----- 625
 626 --------------------------------------------------------NMGD--------------------------Q-T--II--------------G--------------------VID---------------------------T--------------GVWP-E------S-------------E---------S--------------------------------F-N--------------DY---G--V-G-PVPSHW-K--G-------------------------------------------------------GCEPGENFIS----T-NC------------------------------------------------------------------------------------------------------NRKLIGAKYFINGFLAEN-----Q--FNATESPDYIS------------AR-----------------------------------------------------------------------------------------D---F---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIAG----GSFVP-------------------------------NV------------SY--K-GLG------R-GTL----RGG--APR-A--RIAMY---KA---CWYIN-E----LDGV-TC--S------------FSD-------------------------------------I--------MKA--------------I-----------DE---AI--------------------H-----D------G----------V----DV-----------------------------------------LSISLG-GRVPLNS-ET---DL--------------------RD--------------------------GI-------ATGAFH-------AVAK----GI-----V--------------------------------------------------------------------------------------V---------------VCAGG-NA--------GP---------S----SQTVVNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFATP-IILG-NNQ----VIL-------------GQAMY-------------------------------------------------------------------------------------------------------------------------------------------------IGPRY-----------TGT----------LVGEPV----GT------KV-ATF-----S--S--------R-GP--N--------------------SI------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-ATS-----------------------------------------------------------------------------------------------P------------------NDTLNAGGF-VM----------------RSG------TSMAAPVIS----G---------------------------V------------------IA-L----LK----S-------LHPDWS-----------------------------------------------------------------PAA--------------F---------------------RSAI-------VTT------------------------AWR---TDPF-----------------------------------------------------GEQIAAES--------SSLKVPDPFDYGGGLVN---PEKAAE----- 626
 627 --------------------------------------------------------NMGD--------------------------Q-V--II--------------G--------------------FID---------------------------T--------------GVWP-E------S-------------E---------S--------------------------------F-N--------------DN---G--V-G-PIPSHW-K--G-------------------------------------------------------GCESGEKFIS----T-NC------------------------------------------------------------------------------------------------------NRKLIGAKYFINGFLAEN-----EG-FNTTESRDYIS------------AR-----------------------------------------------------------------------------------------D---F---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAG----GSFVP-------------------------------NI------------SY--K-GLA------G-GNL----RGG--APR-A--RIAIY---KA---CWYVD-Q----LGAV-AC--S------------SSD-------------------------------------I--------LKA--------------M-----------DE---SM--------------------H-----D------G----------V----DV-----------------------------------------LSLSLG-AQIPLYP-ET---DL--------------------RD--------------------------RI-------ATGAFH-------AVAK----GI-----I--------------------------------------------------------------------------------------V---------------VCAGG-NS--------GP---------A----AQTVLNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTP-ITLG-NRK----VIL-------------GQALY-------------------------------------------------------------------------------------------------------------------------------------------------RSTRS----PVVKIQPSRT----------LVGQPV----GT------KV-ATF-----S--S--------R-GP--N--------------------SI------SPAIL---K--------------------P------------D-----I------G-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-ATS-----------------------------------------------------------------------------------------------P------------------DSNSSVGGF-DI----------------LAG------TSMAAPVVA----G---------------------------V------------------VA-L----LK----A-------LHPNWS-----------------------------------------------------------------PAA--------------F---------------------RSAI-------VTT------------------------AWR---TDPF-----------------------------------------------------GEQIFAEG--------SSRKVADPFDYGGGIVN---PEKAAD----- 627
 628 --------------------------------------------------------NMGE--------------------------E-V--II--------------G--------------------IVD---------------------------S--------------GVWP-E------S-------------E---------V--------------------------------F-N--------------DN---G--I-G-PVPSHW-K--G-------------------------------------------------------GCVSGENFTS----S-QC------------------------------------------------------------------------------------------------------NKKLIGAKYFINGFLATH-----ES-FNSTESLDFIS------------PR-----------------------------------------------------------------------------------------D---R---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ATIAG----GSYVP-------------------------------SI------------SY--K-GLA------G-GTV----RGG--APR-A--RIAMY---KA---CWYLD-R----FDIN-TC--S------------SAD-------------------------------------I--------LKA--------------M-----------DE---AM--------------------H-----D------G----------V----DV-----------------------------------------LSLSIG-YRFPYFP-ET---DV--------------------RA--------------------------VI-------ATGAFH-------AVLK----GI-----T--------------------------------------------------------------------------------------V---------------VCSGG-NS--------GP---------A----AQTVGNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTP-ITLG-NNK----LIL--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQPSKT----------LVGQPV----GT------KV-ADF-----S--S--------R-GP--N--------------------SI------EPAIL---KTYYIILLQDVCNLMVLSQMQP------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-ATT-----------------------------------------------------------------------------------------------T------------------NKTFNDRGF-IF----------------LSG------TSMAAPTIS----G---------------------------V------------------VA-L----LK----A-------LHRDWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------VTT------------------------AWR---TDPF-----------------------------------------------------GEQIFAEG--------SPRKLADPFDYGGGLVN---PEKAAK----- 628
 629 --------------------------------------------------------NMGE--------------------------Q-M--II--------------G--------------------IID---------------------------S--------------GVWP-E------S-------------E---------V--------------------------------F-N--------------DN---E--I-G-PVPSHW-K--G-------------------------------------------------------GCESGEDFNS----S-HC------------------------------------------------------------------------------------------------------NKKLIGAKYFINAFLATH-----ES-FNSSESLDFIS------------PR-----------------------------------------------------------------------------------------G---Y---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ATIAG----GSYVP-------------------------------NT------------SY--K-GLA------G-GTV----RGG--APR-A--RIAVY---KT---CWYL--D----LDIA-AC--S------------SAD-------------------------------------I--------LKA--------------M-----------DE---AI--------------------H-----D------G----------V----DV-----------------------------------------LSLSLG-FE-PLYP-ET---DV--------------------RD--------------------------GI-------ATGAFH-------AVLK----GI-----T--------------------------------------------------------------------------------------V---------------VCAAG-NA--------GP---------A----AQTVGNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFVTP-MTLG-NNK----VIL----VTTRYIHHNGQAIY-------------------------------------------------------------------------------------------------------------------------------------------------RSNGS----PVVKIQPSRT----------LIGQPV----GT------KV-ASF-----S--S--------R-GP--N--------------------PI------SAAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-ATT-----------------------------------------------------------------------------------------------T------------------NTTFNDRGF-IF----------------LSG------TSMATPTIS----G---------------------------I------------------VA-L----LK----A-------LHPDWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------VTT------------------------AWR---TDPF-----------------------------------------------------GEQIFAEG--------SPRKPADPFDYGGGLVN---PEKATK----- 629
 630 --------------------------------------------------------NMGE--------------------------Q-I--II--------------G--------------------VIDTDFLSLV--LLLIPFLSASMTKMLSVVA--------------GVWP-E------S-------------E---------V--------------------------------F-N--------------DS---G--F-G-PVPSHW-K--G-------------------------------------------------------GCETGENFNS----S-NC------------------------------------------------------------------------------------------------------NKKLIGAKYFINGFLAEN-----ES-FNSTNSLDFIS------------PR-----------------------------------------------------------------------------------------D---L---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------STIAG----GSFVP-------------------------------NI------------SY--K-GLA------G-GTV----RGG--APR-A--HIAMY---KA---CWYLD-D----DDTT-TC--S------------SAD-------------------------------------I--------LKA--------------M-----------DE---AM--------------------H-----D------G----------V----DV-----------------------------------------LSISLG-SSVPLYG-ET---DI--------------------RD--------------------------GI-------TTGAFH-------AVLK----GI-----T--------------------------------------------------------------------------------------V---------------VCSGG-NS--------GP---------D----SLTVTNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFATP-LTLG-NNK----VIL-------------GQAMY-------------------------------------------------------------------------------------------------------------------------------------------------RSSGS----PVVKIQPSKT----------LVGQPV----GT------KV-ATF-----S--S--------R-GP--N--------------------SI------APAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A-T-----------------------------------------------------------------------------------------------T------------------NTTFSDQGF-IM----------------LSG------TSMAAPAIS----G---------------------------V------------------AA-L----LK----A-------LHRDWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------VTT------------------------AWK---TDPF-----------------------------------------------------GEQIFAEG--------SPPKLADPFDYGGGLVN---PEKSAN----- 630
 631 --------------------------------------------------------NMGD--------------------------Q-L--II--------------G--------------------VVD--------------------------------------------------------------------------------------------------------------------------------------------SVTLNW-F--G-------------------------------------------------------FILLKQEYGQ----SLNH------------------------------------------------------------------------------------------------------SVTMVLDQY---QNVGKE-----VQ-LGHAENPEYIS------------PR-----------------------------------------------------------------------------------------D---F---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AATAA----GSFVP-------------------------------DT------------NY--L-GLG------R-GTA----RGG--APR-A--RIAMY---KA---CWHL--V----TGAT-TC--S------------AAD-------------------------------------L--------VKA--------------I-----------DE---AI--------------------H-----D------G----------V----DV-----------------------------------------LSISNG-FSVPLFP-EV---DT--------------------QD--------------------------GV-------AVGAFH-------AVAK----GI-----P--------------------------------------------------------------------------------------V---------------VCAGG-NA--------GP---------S----SQTISNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------QD-------R-SFPTF-ITLG-NNV----TVV-------------GQALYQG-------------------------PDIDFTELVYPEDSGASNETFYGVCEDLAKNPAHIIEEKIVLCFTKSTS----------------YSTMIQAASDVVKLDGYGVIVARNPGHQLSPCFGFPCLAVDYELGTDILFY-IRSTRS----PVAKIQPTRT----------LVGLPV----AT------KV-ATF-----S--S--------R-GP--N--------------------SI------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-ATS-----------------------------------------------------------------------------------------------P------------------NDTFYDKGF-AM----------------KSG------TSMSAPVVA----G---------------------------I------------------VA-L----LK----S-------VHPHWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------VTT------------------------AWR---TDPS-----------------------------------------------------GEPIFADG--------SNRKLADPFDYGGGVVN---SEKAAN----- 631
 632 --------------------------------------------------------NMGY--------------------------N-V--IV--------------G--------------------VID---------------------------S--------------GVWP-E------S-------------E---------M--------------------------------F-N--------------DK---G--F-G-PIPSRW-K--G-------------------------------------------------------GCESGELFNA----SIHC------------------------------------------------------------------------------------------------------NRKLIGAKYFVDGLVAEF-----GV-VNRTQNPEYLS------------PR-----------------------------------------------------------------------------------------D---F---------------------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIG----GSFLP-------------------------------NV------------SY--V-GLG------R-GTA----RGG--APG-V--HIAVY---KA---CW-----------SG-YC--S------------GAD-------------------------------------V--------LKA--------------M-----------DE---AI--------------------H-----D------G----------V----DI-----------------------------------------LSLSLG-PSVPLFP-ET---E-------------------------------------------------HT-------SVGAFH-------AVAK----GI-----P--------------------------------------------------------------------------------------V---------------VIAAG-NA--------GP---------T----AQTISNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------QD-------R-SFPTA-ITLG-NNI----TIL-------------GQA---------------------------------------------------------------------------------------------------------------------------------------------------RSTRS----PIVKIQASKT----------LFGQSV----ST------KV-ATF-----S--S--------R-GP--N--------------------SV------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AIS-----------------------------------------------------------------------------------------------P------------------NSSINDGGF-AM----------------MSG------TSMATPVVS----G---------------------------V------------------VV-L----LK----S-------LHPDWS-----------------------------------------------------------------PSA--------------I---------------------KSAI-------VTT------------------------AWR---TDPS-----------------------------------------------------GEPIFADG--------SSRKLADPFDYGGGLIN---PEKAVK----- 632
 633 --------------------------------------------------------SMGS--------------------------E-A--II--------------G--------------------VVD---------------------------S--------------GIWP-E------S-------------K---------V--------------------------------F-N--------------DQ---G--L-G-PIPKRW-R--G-------------------------------------------------------KCRSGEKFNA----TMHC------------------------------------------------------------------------------------------------------NKKLIGAKYYQSGLLAMN-----GGKFNRIIIRDFKS------------NR-----------------------------------------------------------------------------------------D---A---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATIAG----GSFVP-------------------------------NA------------SF--Y-GLA------R-GTV----RGG--APR-A--RIASY---KA---CWNVV------GWGG-IC--S------------SAD-------------------------------------M--------WKA--------------Y-----------DD---AI--------------------H-----D------Q----------V----DV-----------------------------------------LSVSIG-ASIPEDS-E-----R--------------------VD--------------------------FI-------A--AFH-------AVAK----GI-----T--------------------------------------------------------------------------------------V---------------VAAAG-ND--------GS---------G----AQTICNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTK-ITLG-NNQ----TFF------------------------------------------------------------------GKTILEFDSTHPSSIAGRGVV----------------------------------------AVILAKKPDDRPAPDNS--YIFTDYEIGTHILQY-IRTTRS----PTVRISAATT----------LTGQPA----TP------KV-AAF-----S--S--------R-GP--N--------------------SV------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AVS-----------------------------------------------------------------------------------------------P------------------LDPGAFNGF-KL----------------HSG------TSMSTPVVS----G---------------------------I------------------IV-L----LK----S-------LHPKWS-----------------------------------------------------------------PAA--------------M---------------------RSAL-------VTT------------------------AWR---TSPS-----------------------------------------------------GEPIFAQG--------SNKKLADPFDYGGGLVN---PEKAAK----- 633
 634 --------------------------------------------------------SMGS--------------------------E-A--II--------------G--------------------VVD---------------------------S--------------GIWP-E------S-------------K---------V--------------------------------F-N--------------DQ---G--L-G-PIPKRW-R--G-------------------------------------------------------KCRSGEKFNA----TMHC------------------------------------------------------------------------------------------------------NKKLIGAKYYQSGLLAMN-----GGKFNRIIIRDFKS------------NR-----------------------------------------------------------------------------------------D---A---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATIAG----GSFVP-------------------------------NA------------SF--Y-GLA------R-GTV----RGG--APR-A--RIASY---KA---CWNVV------GWGG-IC--S------------SAD-------------------------------------M--------WKA--------------Y-----------DD---AI--------------------H-----D------Q----------V----DV-----------------------------------------LSVSIG-ASIPEDS-E-----R--------------------VD--------------------------FI-------A--AFH-------AVAK----GI-----T--------------------------------------------------------------------------------------V---------------VAAAG-ND--------GS---------G----AQTICNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTK-ITLG-NNQ----TFFLKLTCCFLLVSNLAESLFTG-------------------------PEISTGLAFLDDD----VDVKGKTILEFDSTHPSSIAGRGVV----------------------------------------AVILAKKPDDRPAPDNS--YIFTDYEIGTHILQY-IRTTRS----PTVRISAATT----------LTGQPA----TP------KV-AAF-----S--S--------R-GP--N--------------------SV------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AVS-----------------------------------------------------------------------------------------------P------------------LDPGAFNGF-KL----------------HSG------TSMSTPVVS----G---------------------------I------------------IV-L----LK----S-------LHPKWS-----------------------------------------------------------------PAA--------------M---------------------RSAL-------VTTGSCFFLFFFFINKPSRTNRSVSFVAWR---TSPS-----------------------------------------------------GEPIFAQG--------SNKKLADPFDYGGGLVN---PEKAAK----- 634
 635 --------------------------------------------------------NMGS--------------------------E-A--II--------------G--------------------VVD---------------------------T--------------GIWP-E------S-------------K---------V--------------------------------F-N--------------DH---G--L-G-PIPQRW-R--G-------------------------------------------------------KCESGEQFNA----KIHC------------------------------------------------------------------------------------------------------NNKLIGAKYYLSGLLAET-----GGKFNRTIIQDFKS------------NR-----------------------------------------------------------------------------------------D---A---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATIAG----GSFVP-------------------------------NV------------SF--Y-GLA------R-GTV----RGG--APR-A--RIASY---KV---CWNVV------GYDG-IC--T------------VAD-------------------------------------M--------WKA--------------F-----------DD---AI--------------------H-----D------Q----------V----DV-----------------------------------------LSVSIG-AGIPENS-EV---DS--------------------VD--------------------------FI-------A--AFH-------AVAK----GI-----T--------------------------------------------------------------------------------------V---------------VAAGG-ND--------GP---------G----AQNITNAA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTK-ITLG-NNQ----TLF-------------AESLFTG-------------------------PEISTSLAFLDSDHN--VDVKGKTILEFDSTHPSSIAGRGVV----------------------------------------AVILAKKPDDLLARYNSIPYIFTDYEIGTHILQY-IRTTRS----PTVRISAATT----------LNGQPA----MT------KV-AEF-----S--S--------R-GP--N--------------------SV------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AVS-----------------------------------------------------------------------------------------------P------------------LDPDAFNGF-GL----------------YSG------TSMSTPVVS----G---------------------------I------------------IA-L----LK----S-------LHPNWS-----------------------------------------------------------------PAA--------------M---------------------RSAL-------VTT------------------------AWR---TSPS-----------------------------------------------------GEPIFAQG--------SNKKLADPFDYGGGLVN---PDKAAQ----- 635
 636 --------------------------------------------------------NLGS--------------------------E-A--II--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------K---------A--------------------------------V-N--------------DQ---G--L-G-PIPKRW-R--G-------------------------------------------------------KCEPGEQFNA----TIHC------------------------------------------------------------------------------------------------------NNKLIGARYYLNGVVAAI-----GGKFNRTIIQDFQS------------TR-----------------------------------------------------------------------------------------D---A---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATIAG----GSFVP-------------------------------NV------------SY--F-GLA------Q-GLV----RGG--APR-A--RIASY---KA---CWNVM-RDEGGGTDG-RC--T------------SAD-------------------------------------M--------WKA--------------F-----------DD---AI--------------------H-----D------G----------V----DV-----------------------------------------LSVSIG-GGIPEDS-EV---DK--------------------LD--------------------------YI-------A--AFH-------AVAK----GI-----T--------------------------------------------------------------------------------------V---------------VAAAG-NE--------GP---------G----AHTVDNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFPTK-ITLG-NNQ----TLF-------------AESLFTG-------------------------PEISTGLAFLDSDSDDTVDVKGKTVLVFDSATP--IAGKGVA----------------------------------------AVILAQKPDDLLSRCNGVPCIFPDYEFGTEILKY-IRTTRS----PTVRITAATT----------LTGQPA----TT------KV-AAF-----S--C--------R-GP--N--------------------SV------SPAILKVIK--------------------PLRLLSMFTSKGLT-----F------L-----------------T-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AIS-----------------------------------------------------------------------------------------------P------------------LNPEEQNGF-GL----------------LSG------TSMSTPVVS----G---------------------------I------------------IA-L----LK----S-------LHPKWS-----------------------------------------------------------------PAA--------------V---------------------RSAL-------VTT------------------------AWR---TSPS-----------------------------------------------------GEPIFAEG--------SNKKLADPFDYGGGLVN---PEKAAK----- 636
 637 --------------------------------------------------------KMGE--------------------------D-I--II--------------G--------------------VLD---------------------------S--------------GVWP-E------S-------------Q---------S--------------------------------F-N--------------DK---G--L-G-PIPKRW-K--G-------------------------------------------------------MCVDGEDFDS----KKHC------------------------------------------------------------------------------------------------------NKKLIGARYYMDSLFRRN-----KT-DSGIPDTEYMS------------AR-----------------------------------------------------------------------------------------E---S---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------PHG-------TH-V-----------------------ASTAG----GSFVS-------------------------------NV------------SD--N-GFG------V-GTI----RGG--APR-A--RIAVY---KV---CW----Q----RVDR-TC--A------------SAD-------------------------------------I--------IKA--------------M-----------DD---AI--------------------A-----D------G----------V----DL-----------------------------------------ITISIG-RPNPVLT-EV---DV--------------------YN--------------------------QI-------SYGAFH-------AVAK----GI-----P--------------------------------------------------------------------------------------V---------------LSAGG-NF--------GP---------G----AYTVQNIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-WYPTP-LTLG-NNV----TLM-------------ARTPY------------------------------------------KGNEIQGDLMFVYSPDEMTSAAKGKVVLTFTTGS----------------EESQAGYVTKLFQVEAKSVIIAAKRNDVIKVSEGLPIIMVDYEHGSTIWKY-LSITRM----PTIKISSAIA----------LNGRLV----AT------KV-ADF-----S--G--------R-GP--N--------------------SI------SPYVL---K--------------------P------------D-----V------A-----------------A-----P-------------G-----------------VA--------------------------------I------------------------------------------------------------------VA-AST-----------------------------------------------------------------------------------------------P------------------ESMGTEEGF-AI----------------QSG------TSMSTPVVA----G---------------------------L------------------VA-L----LR----A-------VHPDWS-----------------------------------------------------------------PAA--------------L---------------------KSAL-------ITT------------------------AST---TDPY-----------------------------------------------------GEPIFSEG--------MTRKLADPFDFGGGLVN---PNKAAD----- 637
 638 --------------------------------------------------------KMGS--------------------------E-A--II--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------Q---------S--------------------------------F-N--------------DT---G--L-G-PIPKRW-K--G-------------------------------------------------------KCLSGNGFDA----KKHC------------------------------------------------------------------------------------------------------NKKLIGAEYLTVGLMEMT-----DGIYDYPSLGESMS------------PR-----------------------------------------------------------------------------------------D---H---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AAIAA----GSFVA-------------------------------NA------------NY--K-GLA------G-GTA----RGA--APH-A--RIAMY---KV---CWREV-G----------C--I------------TAD-------------------------------------L--------LKA--------------I-----------DH---SI--------------------R-----D------G----------V----DV-----------------------------------------ISISIG-TDAPASF-DI---DQ--------------------SD---------------------------I-------GFGSFH-------AVMK----GI-----P--------------------------------------------------------------------------------------V---------------VASAG-NE--------GP---------N----AQTVDNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------LD-------R-SFPIP-ITLG-NNL----TIL-------------GEGLNTF-------------------------PEVGFTNLILSDEMLSRSIEQGKT--------------QGTIVLAFTAN----------------DEMIRKANSITNAGCAGIIYAQSVIDPTVCSSVDVPCAVVDYEYGTDILYY-MQTTVV----PKAKLSPSKT----------LIGRPI----AS------RV-PRF-----S--C--------R-GP--N--------------------SV------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------LS-AVS------------------------------------------------------------------------------------------------------------------------GVY-KF----------------MSG------TSMATPAVS----G---------------------------I------------------VG-L----LR----Q-------THPHWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------VTT------------------------AWK---TDPS-----------------------------------------------------GEPIFSEG--------STRKLADPFDYGGGLIN---PEKVTH----- 638
 639 --------------------------------------------------------DMGS--------------------------E-A--IV--------------G--------------------ILD---------------------------S--------------GIWP-D------S-------------K---------S--------------------------------F-N--------------DN---G--L-G-PIPTRW-K--G-------------------------------------------------------KCVSAEAFNA----S-SC------------------------------------------------------------------------------------------------------NRKLIGAMYYSKGLESKY-----NGSFNAAEKGEVMS------------PL-----------------------------------------------------------------------------------------D---K---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------ASTAV----GSFVP-------------------------------DA------------NV--L-SLA------Q-GTA----RGS--APR-A--RIASY---KV---CWNNE-E----------C--F------------TPD-------------------------------------I--------VKA--------------I-----------DH---AI--------------------R-----D------G----------V----DV-----------------------------------------LSLSLG-SEVPVDF-EV---D---------------------RD--------------------------DF-------AIAAFH-------AVMK----GI-----P--------------------------------------------------------------------------------------V---------------VCAGG-ND--------GP---------E----KETISNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---IT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-EYFTP-ITLG-NNI----TLL------------GQEGLYIG-------------------------EEVGFTDLLFYDDVTREDMEAGKA--------------TGKILLFFQRA----------------NFEDDFAAYAKSKGAVGVIIATQPTDSIDASTVDIAIAYVDNELGMDILLY-IQTTKS----PIAKISPTKT----------FVGRPL----AT------KV-ARF-----S--S--------R-GP--N--------------------SL------SPVIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------SG--------------------------------I------------------------------------------------------------------LA-AVP----------------------------------------------------------------------------------------------------------------------TGGGY-DF----------------MSG------TSMSTPVVS----G---------------------------I------------------VA-L----LR----K-------KRPDWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------VTT------------------------ALQ---TDPS-----------------------------------------------------GEPIAAEG--------SPRKLADPFDYGGGLVN---PVKVAD----- 639
 640 --------------------------------------------------------NMGS--------------------------G-A--II--------------G--------------------VID---------------------------S--------------GIWS-E------S-------------G---------S--------------------------------F-D--------------DD---G--Y-G-PIPKHW-K--G-------------------------------------------------------QCVSADQFSP----A-DC------------------------------------------------------------------------------------------------------NKKLIGAKYYIDGLNADL-----ETSINSTT--EYLS------------PR-----------------------------------------------------------------------------------------D---H---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-V-----------------------SSTAA----GSFVS-------------------------------NM------------TL--P-GLS------S-GSIM---RGG--APK-A--HIAMY---KA---CWDVE-G-------G-MC--S------------VAD-------------------------------------V--------WKS--------------F-----------DE---AI--------------------H-----D------G----------V----DV-----------------------------------------LSVSVG-GSA--LK-TL---DV--------------------EI--------------------------DI-------AIAALH-------AVNK----GI-----P--------------------------------------------------------------------------------------V---------------VSPAG-NE--------GS---------R----SSSVINVS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-SFSTL-ITLE-NNK----TYL-------------GQSLYTG-------------------------PEISFTDVICTGDHSNVDQIT-----------------KGKVIMHFSMG----------------PVRPLTPDVVQKNGGIGLIYVRNPGDSRVDCPVNFPCIYLDMEVGSELYTY-IQTRSS----MKIKISPYKT----------IIGESV----AS------KV-AKS-----S--A--------R-GP--S--------------------SF------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------LT--------------------------------L------------------------------------------------------------------LT-PRI-----------------------------------------------------------------------------------------------P------------------TDEDTSE---FV----------------YSG------TSMATPVIA----G---------------------------I------------------VA-L----LK----I-------SHPNWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------VTT------------------------AMK---TDPY-----------------------------------------------------GERLTVDG--------GNYKVADAFDYGGGLVN---LEKVTD----- 640
 641 --------------------------------------------------------NMGS--------------------------D-L--VI--------------G--------------------FLD---------------------------S--------------GVWP-E------S-------------P---------A--------------------------------Y-N--------------DE---G--L-E-PIPKHW-K--G-------------------------------------------------------KCVAGEDFDP----AKHC------------------------------------------------------------------------------------------------------NKKLVGAKYFTDGFDENN-----SG----ISEEDFMS------------PR-----------------------------------------------------------------------------------------G---Y---------------------R--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TM-V-----------------------SSIAA----SSFVP-------------------------------NV------------SY--G-GLA------P-GVM----RGA--APK-A--RIAMY---KI---VWD--------RALL-MS--S------------TAT-------------------------------------M--------VKA--------------F-----------DE---AI--------------------N-----D------G----------V----DV-----------------------------------------LSISLA-SAAPFRP-ID---SI--------------------TG--------------------------DL-------ELGSFH-------AVMK----GI-----P--------------------------------------------------------------------------------------V---------------IAGAS-NT--------GP---------E----AYTVANVF---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------ID-------R-TFYAD-MTFG-NNI----TII-------------GQAQYTG-------------------------KEVSAGLVYIEHYKTDTSGMLGK------------------VVLTFVKE----------------DWEMASALATTTINKAAGLIVARSGDYQSDIVYNQPFIYVDYEVGAKILRY-IRSSSS----PTIKISTGKT----------LVGRPI----AT------QV-CGF-----S--S--------R-GP--N--------------------GL------SPAIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VT--------------------------------I------------------------------------------------------------------LG-ATS-----------------------------------------------------------------------------------------------Q------------------AYPDSFGGY-FL----------------GTG------TSYATPVVA----G---------------------------L------------------VV-L----LK----A-------LHPDWS-----------------------------------------------------------------PAA--------------L---------------------KSAI-------MTT------------------------AWK---TDPS-----------------------------------------------------GEPIFAEG--------EPRKLADPFDYGAGLVN---AERAKD----- 641
 642 -------------------------------------------SR-------VHL-KYGA--------------------------D-V--IV--------------G--------------------ILD---------------------------T--------------GVWP-E------S-------------E---------S--------------------------------FRD--------------DP---H--L-G-PVPSSW-R--G-------------------------------------------------------TCVGGQQFDP----ATAC------------------------------------------------------------------------------------------------------NRKLIGARYYLAGFESD------LGPLNTSGGAEYRS------------PR-----------------------------------------------------------------------------------------D---R---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAV----GSVSP-------------------------------NS------------SY--FGGLG------R-GAV----RGG--APG-A--RLAVY---KV---CWFK-------DMTG-RC--S------------DAD-------------------------------------I--------LAA--------------F-----------DD---AL--------------------H-----D------G----------V----HV-----------------------------------------ISASLG---SPPPL-SP---LF--------------------ET--------------------------ST-------EVGSFH-------AMQL----GV-----S--------------------------------------------------------------------------------------T---------------VFSAG-ND--------GP---------D----AAMVQNVS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------A---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-RFPTV-ITLG-NNA----SFV-------------GESFVVE----------------------------------DMKMPLVESSSVFTDGTCTFDQLVNRTAASGKMVLCFSTM-----------GMVSSEGAALAVYAGGGSGVIFADTITRKSTQ----DNFLPTVHVDLRQGTQILDYIHVRSRQP---ASVHVSPSRT----------VVGRTP----AP------AV-AYF-----S--S--------R-GP--S--------------------SI------SPNIL---K--------------------P------------D-----V------T-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------PKSPPTVLPLDK-------RS----THW-NF----------------DTG------TSMSCPHVS----G---------------------------I------------------VA-L----LK----S-------IHPAWS-----------------------------------------------------------------PTA--------------V---------------------KSAL-------MTT------------------------AYM---LDNT-----------------------------------------------------GDAMQAGGTL---------KAADAFDAGAGHVD---PLRALD----- 642
 643 --------------------------------------------------------AYGS--------------------------D-I--VV--------------G--------------------IFD---------------------------TGLFISLKLLLLSILGIWP-E------S-------------E---------S--------------------------------FRE--------------TP---E--A-K-PIPSSW-N--G-------------------------------------------------------KCVGGEDFDP----SVHC------------------------------------------------------------------------------------------------------NRKLIGARFYLRGFEET------YGTIDFTRDPEYRS------------PR-----------------------------------------------------------------------------------------D---Y---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAV----GSVVR-------------------------------NV------------SG--FFGLG------R-GTA----RGG--APL-A--RLAVF---KT---CWGK-------DLEG-VC--T------------EAD-------------------------------------I--------LAA--------------F-----------DD---AI--------------------H-----D------G----------V----HV-----------------------------------------ISASFG---YSPPL-SP---FF--------------------ES--------------------------SA-------DIGAFH-------AAER----GI-----S--------------------------------------------------------------------------------------V---------------VFSTG-ND--------GP---------D----PGVVQNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------A---VS---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-SFPTR-IVID-GSF----TLT-------------GQS-------------------------------------------LARS----------------------------------------------------------------------------------PTVPM------------------------VKIGPSKT----------VIGETT----AP------SV-AYF-----S--S--------R-GP--S--------------------SL------SPDIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------IG--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------PRTPPTLLPGDH-------RS----IEW-NF----------------QSG------TSMSCPHVA----G---------------------------V------------------MA-L----LQ----S-------AHPDWS-----------------------------------------------------------------PSA--------------I---------------------RSAI-------MTT------------------------AYT---RDTS-----------------------------------------------------YDLILSGGSM---------KSTDPFDIGAGHIN---PLKAMD----- 643
 644 SKDEALKSIVYSYKHGFSGFAAMLTESQAEIIAKFPEVLSVKPN--------------GE--------------------------D-V--II--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------Q---------S--------------------------------F-D--------------DI---G--Y-G-PVPARW-K--G-------------------------------------------------------TCQTGQAFNA----T-SC------------------------------------------------------------------------------------------------------NRKIIGARWYSKGLPAE------------LLKGEYMS------------PR-----------------------------------------------------------------------------------------D---L---------------------G--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIA----GNQVR-------------------------------NA------------SY--N-NLG------S-GVA----RGG--APR-A--RLAIY---KV---LWG---------GGA-RG--A------------VAD-------------------------------------T--------LAA--------------V-----------DQ---AI--------------------H-----D------G----------V----DV-----------------------------------------LSLSLG-AAG--------------------------------FE--------------------------YY---------GTLH-------AVQR----GI-----S--------------------------------------------------------------------------------------V---------------VFAGG-ND--------GP---------V----PQTVFNAL---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-SFPTL-MTLG-NKE----KLV-------------GQSLY----------------------------SVNSSDF-------QELVVI-------SALSDTTTNVTGKIVLFYAPSDNDVKFMM---PRLTFSEVLNHTAASRAKGLIFAQYTENLLDSLAVCDRILACVLVDFEIARRIVSY-STSTRN----PMIKVSPAIT----------IVGERV---LSP------RV-AAF-----S--S--------R-GP--S--------------------AT------FPAIL---K--------------------P------------D-----V------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A------------------------------------------------------------------------------------------------------------------------KGNSY-VF----------------MSG------TSMACPHVS----A---------------------------V------------------TA-L----LK----S-------VHPSWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------VTT------------------------ASV---IDHF-----------------------------------------------------GAPIEADG--------IPRKLADPFDFGGGHMN---PDRAM------ 644
 645 SKDEALKSIVYSYRHGFSGFAAMLTESQAEILAKLPEVISVRPN--------------GE--------------------------D-V--II--------------G--------------------VVD---------------------------S--------------GIWP-E------S-------------R---------S--------------------------------F-D--------------DT---G--Y-G-PVPARW-K--G-------------------------------------------------------TCQVGEAFNV----T-SC------------------------------------------------------------------------------------------------------NRKIIGARWYSKDVDAD------------SLKGEYMS------------PR-----------------------------------------------------------------------------------------D---L---------------------K--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIA----GGQVW-------------------------------NE------------SY--N-GLA------A-GVA----RGG--APR-A--RLAIY---KV---LWGQS-G---TTGG---G--T------------SAG-------------------------------------I--------LKA--------------I-----------DD---AI--------------------N-----D------G----------V----DV-----------------------------------------LSLSLG-GSS---------------------------------E--------------------------FM---------ETLH-------AVER----GI-----S--------------------------------------------------------------------------------------V---------------VFAAG-NY--------GP---------M----PQTVQNAV---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-SFPTL-MTFG-NNE----KLV-------------GQSFY----------------------------SGNSSDF-------QELVWIGDVIFNSSTLDGGTSNVTGKIILFYAPT-----VMLSTPPRDALGAIINITVEARAKGLIFAQYTANNLDSVTACKGTIPCVLVDFEMARRIIFYMQTSTRT----PVVKVSPTMT----------VTGNGV---LSP------RV-AAF-----S--S--------R-GP--S--------------------ET------FPAIL---K--------------------P------------D-----V------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A------------------------------------------------------------------------------------------------------------------------NGDSY-AF----------------NSG------TSMACPHVS----A---------------------------V------------------TA-L----LK----S-------VYPHWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------VTT------------------------ASV---VDRF-----------------------------------------------------GMPIQAEG--------VPRKVADPFDFGGGHMN---PDRA------- 645
 646 SKDEALKSIVYSYKHGFSGFAAMLTKSQAEALAKFREVVSVKANI-------YHE--LGE--------------------------D-V--II--------------G--------------------VVD---------------------------T--------------GIWP-E------S-------------R---------S--------------------------------F-D--------------DN---G--Y-G-PVPARW-K--G-------------------------------------------------------TCQAGQEFKA----T-NC------------------------------------------------------------------------------------------------------NRKIIGARWYSKGVSEE------------LLRSEYTS------------PR-----------------------------------------------------------------------------------------D---M---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIA----GGQVR-------------------------------GV------------SY--G-GLA------T-GVA----RGG--APR-A--RLAIY---KV---CW-----------VG-RC--T------------HAA-------------------------------------V--------LAA--------------I-----------DD---AI--------------------H-----D------G----------V----DV-----------------------------------------LSLSLG-GAG--------------------------------FE--------------------------YD---------GTLH-------AVQR----GI-----S--------------------------------------------------------------------------------------V---------------VFAGG-ND--------GP---------V----PQTVTNAV---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-SFPTL-MTLG-SDE----KLV-------------GQSLHHN-------------------------ASAISSDF-------KDLVYAGSC--DPRSL--ALSNVTGKIVFCYAPA-----AAAITPPRLALPLAINYTMEAGAKGLIFAQYAANVLGRLTACNGIMPCVLVDFEIAQRIFSY-GVIAES----PVVKVSPTKS----------VVGNGV---LPP------RV-ALF-----S--S--------R-GP--S--------------------PL------FPGIL---K--------------------P------------D-----V------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A------------------------------------------------------------------------------------------------------------------------KGDSY-VL----------------FSG------TSMACPHVS----A---------------------------V------------------TA-L----LK----S-------VYPNWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------VTT------------------------ASV---TDHF-----------------------------------------------------GMEIQAEG--------VPRKVADPFDFGGGQID---PDRAV------ 646
 647 SKDEALQSIVYSYKHGFSGFAAMLTKSQAETIAKFPEVISVKPNT-------YHQ-NYGE--------------------------D-T--II--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------P---------S--------------------------------F-D--------------DA---G--Y-G-PVPARW-K--G-------------------------------------------------------TCQTGQEFNA----T-GC------------------------------------------------------------------------------------------------------NRKIIGARWFTGGLSAS------------SLKGDYMS------------PR-----------------------------------------------------------------------------------------D---F---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIA----GSPVR-------------------------------GT------------SYYGG-GLA------A-GVA----RGG--APR-A--RLAIY---KV---LWG---------RAG-RG--S------------DAA-------------------------------------F--------LAA--------------I-----------DH---AI--------------------N-----D------G----------V----DV-----------------------------------------LSLSLG-SAG--------------------------------SE--------------------------IV---------GSLH-------AVQR----GI-----S--------------------------------------------------------------------------------------V---------------VFAGG-ND--------GP---------V----PQTVTNAV---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-AFPTL-MTLG-NDE----KLV-------------GQSLHHN-------------------------ASSISNDF-------KALVYAGSC--DVLSLSSSSSNVTGKIVLCYAPA-----KAAIVPPGLALSPAINRTVEAGAKGLIFAQYASEGLDTLAACDGIMPCVLVDFEIAQRILSY-GELTEN----PVVKVSRTVN----------VVGNGV---LSP------RV-ASF-----S--S--------R-GP--S--------------------PA------FPDIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A------------------------------------------------------------------------------------------------------------------------ERSAY-VF----------------RSG------TSMACPHVS----A---------------------------V------------------TA-L----IK----S-------VHRDWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------ITT------------------------ASV---TDRF-----------------------------------------------------GMPIQAEG--------VPRKLADPFDFGGGHID---PIRAV------ 647
 648 SKDEALQSIVCSYKHGFSGFAAMLTKSQAETIAKFPEVISVKPNT-------YHE-NYGE--------------------------N-I--II--------------G--------------------VID---------------------------S--------------GIWP-E------S-------------R---------S--------------------------------F-D--------------DA---G--Y-S-PVPARW-R--G-------------------------------------------------------TCQIGQEFNA----T-GC------------------------------------------------------------------------------------------------------NRKIIGARWFTGGLSDE------------ALKGDYMS------------PR-----------------------------------------------------------------------------------------D---F---------------------G--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTIA----GSPVR-------------------------------GA------------S-YGG-VLA------A-GMA----RGG--APS-A--RLAIY---KV---LWG---------QNG-RG--S------------DAA-------------------------------------I--------LAA--------------I-----------DH---AI--------------------N-----D------G----------V----DV-----------------------------------------LSLSLG-EAG--------------------------------SE--------------------------NV-------GFGSLH-------AVQR----GI-----S--------------------------------------------------------------------------------------V---------------VFAGG-ND--------GP---------V----PQTVMNAV---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-AFPTL-MTLG-NNE----KLV-------------GQSLHHT-------------------------ASSISNDF-------KAFAYAGSC--DALSL--SSSNVTGKIVLCYAPA-----EAAIVPPRLALSRAINRTVEAGAKGLIIARYAADDLDTLAECNGIMPCVLVDFEIAQRILSY-GDITDN----PVVKVSRTVS----------VVGNGV---LSP------RV-ASF-----S--S--------R-GP--S--------------------PT------FPDIL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-A------------------------------------------------------------------------------------------------------------------------ERSSY-VF----------------KSG------TSMACPHVS----A---------------------------V------------------TA-L----LK----S-------VHRDWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------ITT------------------------ASV---TDRF-----------------------------------------------------GMPIQAEG--------VPRKLADPFDFGGGHMD---PVRAV------ 648
 649 ---------------------------LELDTQQGGRNATAGS---------------GD--------------------------G-V--II--------------G--------------------VLD---------------------------T--------------GIFP-D------H-------------P---------S--------------------------------F-S--------------GV---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNG----SA-C------------------------------------------------------------------------------------------------------NNKLIGAQTF--------------LSGGSSPPGARAP------------PT-----------------------------------------------------------------------------------------D---E---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTTA----GALVP-------------------------------GA------------QV--L-GQG------S-GSA----SGI--APR-A--HVAMY---KV---CADE------------GC--D------------SVD-------------------------------------I--------LAG--------------I-----------DA---AV--------------------S-----D------G----------C----DV-----------------------------------------ISMSLG--GDSV-P-FF-------------------------ND--------------------------SI-------AIGTFA-------AAQK----GI-----F--------------------------------------------------------------------------------------I---------------SMAAG-NS--------GP---------I----HSTLSNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------M--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I-TSF-----S--S--------R-GP--S--------------------TQ------NPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVG---PPAF--D--P-R-----PTY-NI----------------ISG------TSMSTPHLA----G---------------------------I------------------AA-L----IK----S-------KHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------ADV---NDRS-----------------------------------------------------GEAILDEQ--------H--NIADLFAVGAGHVN---PEKAV------ 649
 650 -------LLHAYHHVASGFAARLTRGELAAITAMPGFVAAVPSVV-------Y---KVGD--------------------------G-V--II--------------G--------------------VLD---------------------------T--------------GIFP-D------H-------------P---------S--------------------------------F-S--------------GA---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNG----SA-C------------------------------------------------------------------------------------------------------NNKLIGAQTF--------------LSGGSSPPGARAP------------PT-----------------------------------------------------------------------------------------D---E---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GALVP-------------------------------GA------------QV--F-GQG------S-GSA----SGI--APR-A--HVAMY---KV---CAGE------------SC--D------------DVD-------------------------------------I--------LAG--------------I-----------DA---AV--------------------S-----D------G----------C----DV-----------------------------------------ISMSLG--GDSV-P-FF-------------------------ND--------------------------SF-------AIGTFA-------AAEK----GI-----F--------------------------------------------------------------------------------------V---------------SMAAG-NS--------GP---------I----HSTLSNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-LILAK-VILG-N----NASFD-------------GESILQP-----------------NTTATV--GLVY-AGASP-----TP-----DAQFCDHGSLDGLD-VKGKIVLCDL-D-----------GFGS--DAGTEVLRAGGAGLILANPFINGYSTFTDFVYALPASQVSYAAGVLIKTY-INSTAN----PTAQIAFKGT----------VLGTSP----AP------AI-TSF-----S--S--------R-GP--S--------------------IQ------NPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVG---PSAF--D--S-T-----PTY-NI----------------ISG------TSMSTPHLA----G---------------------------I------------------AA-L----IK----S-------KHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------ADV---NDRS-----------------------------------------------------GGPILDEQ--------H--NTANLFAVGAGHVN---PEKAVD----- 650
 651 -------LLHEYHHVASGFAARLTRRELDAISAMPGFVAAFPDVI-------Y---KVGD--------------------------G-V--II--------------G--------------------VLD---------------------------T--------------GVFP-N------H-------------P---------S--------------------------------F-S--------------GA---G--M-P-PPPARW-K--G-------------------------------------------------------RC----DFNG----SA-C------------------------------------------------------------------------------------------------------NNKLIGAQTF--------------INGSSSPGTA---------------PT-----------------------------------------------------------------------------------------D---E---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GAVVP-------------------------------GA------------QV--L-DLG------S-GSA----SGM--APN-A--HVAMY---KV---CGEE------------DC--S------------SAD-------------------------------------I--------LAG--------------I-----------DA---AV--------------------S-----D------G----------C----DV-----------------------------------------ISMSLG--GPSL-P-FF-------------------------RD--------------------------SI-------AIGTFA-------AAEK----GI-----F--------------------------------------------------------------------------------------V---------------SMAAG-NS--------GP---------A----HGTLSNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-LFLAQ-AILG-N----GASFD-------------GETVFQP-----------------NSTTAV--PLVY-AGSSS-----TP-----GAQFCANGSLNGFD-VKGKIVLCDR-G-----------DGVARIDKGAEVLRAGGAGMILANQVLDGYSTLAD-PHVLPASHVSYAAGVLIKNY-INSTAN----PTAQLAFKGT----------VVGTSP----AP------AI-TSF-----S--S--------R-GP--S--------------------FQ------NPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVG---PPRF--D--F-R-----PTF-NI----------------ISG------TSMSTPHLA----G---------------------------I------------------AA-L----IK----S-------KHPYWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------MTT------------------------AEV---NDRS-----------------------------------------------------GDPIPDEQ--------H--RPADLFAVGAGHVN---PVKAVD----- 651
 652 -------LLHAYHHVASGFAARLTPRELEAMSAMPGFVAAVPNRV-------Y---K-----------------------------------------------------------------------LLD---------------------------S--------------GVTP-D------H-------------P---------S--------------------------------F-S--------------GD---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNGR---ST-C------------------------------------------------------------------------------------------------------NNKLIGARAF-----------DTVPNATEG----SLS------------PI-----------------------------------------------------------------------------------------D---E---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GAVVP-------------------------------GA------------QV--L-GQG------K-GTA----SGI--APR-A--HVAMY---KV---CGLE------------DC--T------------SAD-------------------------------------I--------LAG--------------I-----------DA---AV--------------------A-----D------G----------V----DI-----------------------------------------ISMSLG--GPSL-P-FH-------------------------ED--------------------------SL-------AVGTFA-------AAEK----GI-----F--------------------------------------------------------------------------------------V---------------SMSAG-NS--------GP---------N----HTTLSNDA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-LISAV-VHLG-N----GLSFE-------------GESVYQP-----------------EVSASVLYPLVY-AGASS-----VE-----DAQFCGNGSLDGLD-VKGKIVLCER-G-----------NDVGRIDKGSEVLRAGGVGMILANQLIDGFSTIAD-VHVLPASHVSHAAGDAIKNY-IKSTAR----PMAQFSFKGT----------VLGTSP----AP------AI-TSF-----S--S--------R-GP--S--------------------MQ------NPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVG---PPSA--QKSS-GA----PTF-NF----------------ESG------TSMSAPHLS----G---------------------------I------------------AA-L----IK----S-------KNPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------ADV---TDRY-----------------------------------------------------GKAILDEQ--------H--GAADFFAFGAGHVN---PDKAMD----- 652
 653 -----------------------QRNQ----------------SG-------L-----GA--------------------------G-V--II--------------G--------------------VID---------------------------T--------------GIFP-D------H-------------P---------S--------------------------------F-S--------------DY---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNG----TA-C------------------------------------------------------------------------------------------------------NNKLIGARNF-----------VAALNNGTS--GAPVP------------PV-----------------------------------------------------------------------------------------D---E---------------------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GAVVP-------------------------------DA------------NV--L-GQA------M-GIA----AGM--ATR-A--HIAMY---KV---C-TR------------GC--S------------VSD-------------------------------------I--------LAG--------------I-----------DA---AV--------------------A-----D------G----------C----DV-----------------------------------------ISISLG--GPAL-P-FH-------------------------QD--------------------------PV-------AVATFG-------AMEK----GV-----F--------------------------------------------------------------------------------------V---------------SMAAG-NS--------GP---------V----ESSLLNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-SI-----------------------------------------------------------------------------------------------------------------------------------------------------------TLAN-AHVLPASHVGYAASTAIKSY-INSTTI----PVARISFQGT----------VLGTSP----AP------SI-VFF-----S--S--------R-GP--S--------------------LQ------HTGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVA---PPST--PVLP-G-----PTF-NI----------------ISG------TSMSTPHLS----G---------------------------I------------------AA-A----IK----S-------KHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------AEI---TDRS-----------------------------------------------------GNPILNEQ--------H--VAANLFATGAGHVN---PTKAA------ 653
 654 -------LLHAYHHVVTGFAARLTRQELAAISAMPGFLSAVPDST-------Y-----GA--------------------------G-V--IV--------------G--------------------VID---------------------------T--------------GIFP-D------H-------------P---------S--------------------------------F-S--------------DH---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNG----TT-C------------------------------------------------------------------------------------------------------NNKLIGARNF-----------VAALNNGTS--GVPVP------------PV-----------------------------------------------------------------------------------------D---L---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GAVVP-------------------------------GA------------NV--L-GQA------M-GSA----SGM--ATR-A--HLAMY---KV---CYTN------------RC--S------------DSD-------------------------------------M--------LAG--------------V-----------DT---AV--------------------A-----D------G----------C----DV-----------------------------------------ISISLA--GPAL-P-FH-------------------------QD--------------------------PV-------LVATFG-------AVEK----GV-----F--------------------------------------------------------------------------------------V---------------SMAAG-NS--------GP---------V----ESSLLNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-SIRST-VQLG-N----GVSFH-------------GESLYQP-----------------HDSPALFSPLVH-AAASG-----KP-----LAEFCGNGTLDGFD-VKGKMVLCES-G-----------GNISATLKGRVVQSAGGAGMILKNQFLQGYSTFAD-AHVLPASHVGYTASTAIESY-INSTAN----PVARISFPGT----------ILGTSP----AP------SI-VFF-----S--S--------R-GP--S--------------------RQ------HTGIL---K--------------------P------------D-----I------A-----------------G-----P-------------G-----------------VN--------------------------------V------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------F-QVG---PPST--PVLP-G-----PTF-NI----------------ISG------TSMSTPHLS----G---------------------------I------------------AA-V----IK----S-------KHSDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------AEI---TDRS-----------------------------------------------------GNPILNEQ--------R--APANLFATGAGHVN---PTKAVD----- 654
 655 --------------------------------------------------------NYGK--------------------------G-V--II--------------G--------------------VID---------------------------T--------------GILP-D------H-------------P---------S--------------------------------F-S--------------DV---G--M-P-PPPAKW-K--G-------------------------------------------------------VC----ESNFT---NK-C------------------------------------------------------------------------------------------------------NNKLIGARSY-----------QLGHGS----------------------PI-----------------------------------------------------------------------------------------D---D---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GAFVN-------------------------------GA------------NV--F-GNA------N-GTA----AGV--APF-A--HIAVY---KV---CNSD------------GC--A------------DTD-------------------------------------V--------LAA--------------M-----------DA---AI--------------------D-----D------G----------V----DI-----------------------------------------LSISLG--GGGSSD-FY-------------------------SN--------------------------PI-------ALGAYS-------ATER----GI-----L--------------------------------------------------------------------------------------V---------------SCSAG-NN--------GP---------S----TGSVGNEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------QD-------R-KLKAT-VKLG-N----REEFE-------------GESAYR---------------------------------------------------------------------------------------------------------------------------------------------P-KNSTSN----PVATITFQGT----------IIGDKN----AP------IV-AAF-----S--S--------R-GP--S--------------------GA------SIGIL---K--------------------P------------D-----I------I-----------------G-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWP-------------------------------------------------------------------------------------------------------TSVD--DNKN-TK----STF-NI----------------ISG------TSMSCPHLS----G---------------------------V------------------RA-L----LK----S-------THPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAM-------MTT------------------------ADT---LNLA-----------------------------------------------------NSPILDER--------L--LPADIYAIGAGHVN---PSRAND----- 655
 656 DPGALPRLIYSYRNVVNGFAARLSTDEVHRMSKMDWFVRAIPEKT-------YTL-NMGE--------------------------G-M--II--------------G--------------------VLD---------------------------G--------------GISP-G------H-------------P---------S--------------------------------F-D--------------GT---G--M-P-PPPAKW-K--G-------------------------------------------------------RC----DFNG----SA-C------------------------------------------------------------------------------------------------------NNKLIGARSF-----------YESAKWKWKGIDDPVL------------PI-----------------------------------------------------------------------------------------D---E---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------VHG-------TH-V-----------------------SSTAA----GAFVP-------------------------------GA------------NA--M-GSG------I-GTA----AGM--APR-A--HLALY---QV---CFED----------K-GC--D------------RDD-------------------------------------I--------LAA--------------I-----------DD---AV--------------------D-----E------G----------I----DV-----------------------------------------LSMSLG--DDSAGD-FA-------------------------AD--------------------------PI-------ALGGFS-------SIMR----GV-----F--------------------------------------------------------------------------------------V---------------CTAAG-NN--------GP---------D----PATVANEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ND-------R-RFVAN-VLLG-D----GAEIS-------------GESHYQP-----------------REYVSVQRPLVKDPGADG-----T----------CSNKSLLTADNVRGKIVLCHT-G-----------GDATNLEKGVMLRDAGADAFIIISPDFTGTVIQPK-AHALPATQVEFLTAEKIEAY-INSTQN----PTAQLAFKGT----------EYGNRM----SP------VV-APF-----S--S--------R-GP--S--------------------KQ------NQGII---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IG-GVP-----------------------------------------------------------------------------------------------R-PAGLAQPPN------E-LA----KKF-DI----------------MSG------TSMAAPHIS----G---------------------------I------------------AA-L----MK----K-------AHPTWS-----------------------------------------------------------------PAA--------------I---------------------KSAM-------MTT------------------------TDT---RDHR-----------------------------------------------------RMPILDQD--------G--KPANMFSLGAGFIN---PAKAMD----- 656
 657 --------------------------------------------G-------F-----GK--------------------------G-V--VI--------------G--------------------LLD---------------------------T--------------GILP-S------H-------------P---------S--------------------------------F-G--------------DA---G--M-P-PPPKKW-K--G-------------------------------------------------------AC----EFTAVAGTGG-C------------------------------------------------------------------------------------------------------NNKVIGARAF-----------------GSASVNSTAP------------PV-----------------------------------------------------------------------------------------D---D---------------------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNFVQ-------------------------------NA------------DV--R-GNA------H-GTA----SGM--APH-A--HLAIY---KV---CSRS------------RC--S------------IMD-------------------------------------V--------VAG--------------L-----------DA---AV--------------------K-----D------G----------V----DV-----------------------------------------ISFSID--A-S-DG-AQ---FN--------------------YD--------------------------LV-------AVATYK-PWSTA-SRQR--------------------------------------------------------------------------------------------------------------------AAG-NA--------GP---------C----RRLRGQQR---------------------------------------------------------------------------------------------------------------------------------------A-V--------------------------------D---AD---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TD-------R-AIRTT-VTLG-N----GEKLE-------------GDG---------------------------------------------------KIVLCESRGIGEHV-AQGQTVNAYN-----------------------------GAGMVLMNKATEGYTTFAD-AHVLPASHVSYAAGAKLTAY-LKSTPK----PTASITFKGT----------VMGSSP----AP------AV-AFF-----S--S--------R-GP--S--------------------KA------SPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------MN--------------------------------I------------------------------------------------------------------LA-AWA-----------------------------------------------------------------------------------------------P-SEM---HPEF--AD-D-AS----LPF-FM----------------ESG------TSMSAPHLS----G---------------------------I------------------AA-V----IK----S-------LHPTWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------MTT------------------------SDT---ADHA-----------------------------------------------------GVPIKDEQ--------Y--RKASSYAMGAGYVN---PGRAAD----- 657
 658 -------------------------------------------SG-------F-----GR--------------------------G-V--VI--------------G--------------------ILD---------------------------T--------------GILP-S------H-------------P---------S--------------------------------F-G--------------DD---G--L-D-PPPKTW-N--G-------------------------------------------------------TC----EFKAIAG-GG-C------------------------------------------------------------------------------------------------------NNKIVGARAF-----------------GSAAVNSSAP------------PV-----------------------------------------------------------------------------------------D---D---------------------A--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSFVE-------------------------------NA------------N--------------------------------------------V---CTRS------------RC--S------------IMD-------------------------------------I--------IAG--------------L-----------DA---AV--------------------K-----D------G----------V----DV-----------------------------------------LSFSIG--ASS-SG-TQ---FN--------------------YD--------------------------PV-------AIAAFK-------AMER----GI-----V--------------------------------------------------------------------------------------V---------------SCAAG-NA--------GP-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPGSVG-------------N-----------------------------GAPWMLTVAA---------------------------------------------------------------GTMP----SP------AV-TFF-----S--S--------R-GP--S--------------------KA------SPGIL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------MN--------------------------------I------------------------------------------------------------------LA-AWA-----------------------------------------------------------------------------------------------P-SES---HPEF--SDGG-VS----LSF-FV----------------ESG------TSMSTPHLS----G---------------------------I------------------AA-L----LK----S-------LHPSWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTS------------------------SDA---VDRT-----------------------------------------------------GVPLKDEQ--------Y--RHATFYAMGAGYVN---PALA------- 658
 659 --------------------------------------------N-------A---GYGK--------------------------G-V--II--------------G--------------------LLD---------------------------T--------------GIYA-A------H-------------P---------S--------------------------------F-G--------------DH---G--I-S-PPPARW-K--G-------------------------------------------------------WC----KA------AH-C------------------------------------------------------------------------------------------------------NNKLVGVTSF------------VGVD-----------------------SH-----------------------------------------------------------------------------------------D---Q---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-T-----------------------SSTAA----GNFVS-------------------------------GA------------SF--H-GHG------S-GIA----TGI--APG-A--HIAMY---KV---CKAG------------DC--E------------EFA-------------------------------------I--------LAG--------------I-----------DA---AI--------------------K-----D------G----------V----DV-----------------------------------------LSISL---ADSGNI-FD---DY--------------------KN--------------------------AI-------SIGSFS-------AVSK----GI-----V--------------------------------------------------------------------------------------V---------------VCAAG-NS--------GS---------T----RSSV---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWT-------------------------------------------------------------------------------------------------------PNED--YSAL-AA----TPF-KV----------------SSG------TSMATPHVS----G---------------------------V------------------AA-L----VK----S-------IHPSWS-----------------------------------------------------------------PAA--------------I---------------------KLAI-------LTT------------------------ADA---VSND-----------------------------------------------------GGPILDHR--------H--EKASPYMKGAGHVN---PARAA------ 659
 660 DVSGKPCLLHSYTEAFSGFAARLTDVELDAVAKKPGFVRAFPDRM-------L---QYGK--------------------------G-V--IV--------------G--------------------LLD---------------------------T--------------GIYA-K------H-------------P---------S--------------------------------F-D--------------DH---G--V-P-PPPARW-K--G-------------------------------------------------------SC----KA------ER-C------------------------------------------------------------------------------------------------------NNKLIGAMSF------------TGDDN----------------------SD-----------------------------------------------------------------------------------------D---D---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GNFVA-------------------------------GA------------SS--H-AVS------A-GTA----AGI--APG-A--HIAMY---KV---CNSL------------GC--T------------ESA-------------------------------------V--------LAG--------------L-----------DK---AV--------------------K-----D------G----------V----DV-----------------------------------------LSMSLG--GGSSFR-FD-------------------------QD--------------------------PI-------AMATFR-------AASK----GV-----I--------------------------------------------------------------------------------------V---------------VCSAG-NN--------GP---------T----PGSVTNDA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------VD-------R-SFDAA-VHLG-N----GKIIE-------------GQALNQV-----------------VKPSSELYPLLY-------------------SEERRQCSYAGESSVVGKMVVCEF-V-----------LGQESEIRG--IIGAGAAGVVLFNNEAIDYATVLA-DYNSTVVQVTAADGAVLTNY-ARSTSS----SKAALSYNNT----------VLGIRP----AP------IV-ASF-----S--S--------R-GP--S--------------------RS------GPGVL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWP-------------------------------------------------------------------------------------------------------PRTD-----G-GY----GPF-NV----------------LSG------TSMSTPHVS----G---------------------------V------------------AA-L----IK----S-------VHPGWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------VTT------------------------ADA---VNST-----------------------------------------------------GGSILDEQ--------H--RKANVFAAGAGHVN---PARAAD----- 660
 661 GESGKARLVHSYTEVFDGFASRLTNDELGVVAKKPGFVRAFPDRK-------R-Q-LYGK--------------------------G-V--IIGLLDTGIHATHPFIG--------------------LLD---------------------------T--------------GIHA-T------H-------------P---------S--------------------------------F-D--------------DH---G--I-P-PAPKRW-K--G-------------------------------------------------------SC----KGSA----TR-C------------------------------------------------------------------------------------------------------NNKIIGARSF-----------------------IGGD------------SE-----------------------------------------------------------------------------------------D---S---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GNFVS-------------------------------NA------------SL--N-GLG------V-GTA----AGI--VPG-A--HISMH---KV---CTDD------------SC--E------------DSD-------------------------------------V--------LAS--------------L-----------DM---AI--------------------K-----D------G----------V----DV-----------------------------------------LSLSIG--MGND-T-LD-------------------------KN--------------------------VV-------AIGAFS-------AISK----GI-----I--------------------------------------------------------------------------------------V---------------VCAGG-NE--------GP---------A----MSSTTNDA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-SFSAD-VHLN-N----ADKIS-------------GEALNQV-----------------AKLSSMPYPLHH-------------------DKKQRSCNYDSFDGLAGKILVCES---------------KEPMPQIYNITHNGVAGAILVNTVTDGYTLMLQ-DYGSGVVQVTAADGLSILNY-VTSVSN----PTATFTYNNT----------FLGVHR----AP------VV-ALF-----S--S--------R-GP--S--------------------LV------SPGVL---K--------------------P------------D-----I------M-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------P-KTK------------D-ES----AVF-DV----------------ISG------TSMATPHVS----G---------------------------V------------------AV-L----IK----G-------IHPDWS-----------------------------------------------------------------PAT--------------I---------------------KSAI-------LMT------------------------SDA---LDNA-----------------------------------------------------GGPIMDEQ--------H--RKASAYATGVGHVN---AARA------- 661
 662 -------LVFSFAHVVSGFAARLTDAEAGELSRLPWCVDALPDAR-------Y---RLGE--------------------------G-V--IV--------------G--------------------VLD---------------------------N--------------GIDP-R------H-------------V---------S--------------------------------F-S--------------DD---G--MPP-PPPAKW-R--G-------------------------------------------------------KCDFG---------GTPC------------------------------------------------------------------------------------------------------NRKLIGGK-----------------------------------------AR-----------------------------------------------------------------------------------------A---M---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TH-T-----------------------SSTAV----GAFVG-------------------------------GV------------KL--FRADA--------GNA----SGM--APR-A--HLAFY---EV---CLAD------------TC--S------------ATE-------------------------------------I--------LTA--------------T-----------EK--GAF--------------------V-----D------G----------V----DV-----------------------------------------ISISAG----DDTQ-KP---FY--------------------KD--------------------------LI-------AVGSFS-------AVMS----GV-----F--------------------------------------------------------------------------------------V---------------STSAG-NS--------GP---------V----SRTVTNCA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---LT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MG-------R-HVVSK-VQLG-NGV----ALY-------------GETLKRFKPVRNRPLVFIAGMFADGALNATD--------------------------------------VRGKIVATERKE--------------DPITLGEMIQKAGGVGMVSWSSAVRGNATTPMDDLAIASSRISHADGEAIVAY-INSTPN----PTASIRFGGA----------QVNRSS----RP------AI-AEY-----S--S--------R-GPC-N--------------------VS------NVGVL---K--------------------P------------D-----I------T-----------------G-----P-------------G-----------------TS--------------------------------I------------------------------------------------------------------AA-AVP-----------------------------------------------------------------------------------------------GGGNNSALPTRM---------------F-GL----------------LSS------TSMSTPHLS----G---------------------------I------------------VA-M----LK----K-------ARPEWS-----------------------------------------------------------------PAA--------------I---------------------KSAM-------MTT------------------------ADV---AHLD-----------------------------------------------------GTPIVDETT----------GRPNCFAMGAGLVN---PTRALD----- 662
 663 --------------------------------------------------------GTAS--------------------------D-V--VV--------------G--------------------VLD---------------------------T--------------GVWP-E------R-------------A---------S--------------------------------Y-D--------------DA---G--F-G-PVPTGW-K--G-------------------------------------------------------KCEEGNDFNA----SA-C------------------------------------------------------------------------------------------------------NKKLIGARFFLTGY--E------ASKGPVDVSKESRS------------PR-----------------------------------------------------------------------------------------D---N---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GSAVR-------------------------------GA------------DL--L-GYA------S-GTA----KGM--APR-A--RVATY---KV---CW-V----------G-GC--F------------SSD-------------------------------------I--------LKG--------------M-----------EV---AV--------------------A-----D------G----------V----DV-----------------------------------------LSLSLG-----GGT-SD---YY--------------------RD--------------------------SI-------AVGAFS-------AMEK----GI-----F--------------------------------------------------------------------------------------V---------------SCSAG-NA--------GP---------G----AASLTNGA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---TT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-DFPAH-VTLG-NGK----NYT-------------GVSLYSG-----------------KQLPTTPVPFVYAGNA----------SNSSMGALCMTGSLIPEK-VAGKIVLCDR-------------GTNARVQKGFVVKDAGGAGMVLANTAANGEELVAD-AHILPGSGVGEKAGNAMRTY----ASSDPN-PTANIVFAGT----------KVGIQP----SP------VV-AAF-----S--S--------R-GP--N--------------------TV------TPGVL---K--------------------P------------D-----L------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWS-----------------------------------------------------------------------------------------------G-SIG---PSGI--AGDN-RR----SSF-NI----------------ISG------TSMSCPHVS----G---------------------------L------------------AA-L----LR----S-------AHQDWT-----------------------------------------------------------------PAA--------------I---------------------RSAL-------MTT------------------------AYTVYPNGNY-----------------------------------------------------NNGILDVA------T-G--RPATPLDIGAGHVD---PSKAVD----- 663
 664 --------------------------------------------------------GSYS--------------------------D-V--VV--------------G--------------------VLD---------------------------T--------------GVWP-E------S-------------K---------S--------------------------------Y-S--------------DE---G--F-G-PIPSSW-K--G-------------------------------------------------------GCEAGTNFTA----SL-C------------------------------------------------------------------------------------------------------NRKLIGARFFARGY--E------STMGPIDESKESRS------------PR-----------------------------------------------------------------------------------------D---D---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GSVVE-------------------------------GA------------SL--L-GYA------S-GTA----RGM--APR-A--RVAVY---KV---CW-L----------G-GC--F------------SSD-------------------------------------I--------LAA--------------I-----------DK---AI--------------------A-----D------N----------V----NV-----------------------------------------LSMSLG-----GGM-SD---YY--------------------RD--------------------------GV-------AIGAFA-------AMER----GI-----L--------------------------------------------------------------------------------------V---------------SCSAG-NA--------GP---------S----SSSLSNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---TT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-DFPAL-AILG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TTDPN-PTASISILGT----------VVGVKP----SP------VV-AAF-----S--S--------R-GP--N--------------------SI------TPNIL---K--------------------P------------D-----L------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-AAG---PTGL--ASDS-RR----VEF-NI----------------ISG------TSMSCPHVS----G---------------------------L------------------AA-L----LK----S-------VHPEWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------MTT------------------------AYKTYKDG--------------------------------------------------------KPLLDIA------T-G--KPSTPFDHGAGHVS---PTTATN----- 664
 665 --------------------------------------------------------VTDH--------------------------D-V--VV--------------G--------------------VLD---------------------------T--------------GIWP-E------S-------------E---------S--------------------------------F-N--------------DT---G--M-S-PVPATW-R--G-------------------------------------------------------ACETGKRFLK----RN-C------------------------------------------------------------------------------------------------------NRKIVGARVFYRGY--E------AATGKIDEELEYKS------------PR-----------------------------------------------------------------------------------------D---R---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------AATVA----GSPVK-------------------------------GA------------NL--F-GFA------Y-GTA----RGM--AQK-A--RVAAY---KV---CW-V----------G-GC--F------------SSD-------------------------------------I--------LSA--------------V-----------DQ---AV--------------------A-----D------G----------V----QV-----------------------------------------LSISLG-----GGV-ST---YS--------------------RD--------------------------SL-------SIATFG-------AMEM----GV-----F--------------------------------------------------------------------------------------V---------------SCSAG-NG--------GP---------D----PISLTNVS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---TT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-DFPAT-VKIG-TMR----TFK-------------GVSLYKG-----------------RTV------------------------------------------------------------------------------------------------------------------------------MTSKK-ATASLEILGT----------RIGIKP----SP------VV-AAF-----S--S--------R-GP--N--------------------FL------SLEIL---K--------------------P------------D-----L------L-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-DMA---PSSL--SSDP-RR----VKF-NI----------------LSG------TSMSCPHVS----G---------------------------V------------------AA-L----IK----S-------RHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT------------------------AYV---HDNM-----------------------------------------------------FKPLTDAS------G-A--APSSPYDHGAGHID---PLRATD----- 665
 666 --------------------------------------------------------AASH--------------------------D-V--VI--------------G--------------------VLD---------------------------T--------------GVWP-E------S-------------P---------S--------------------------------F-S--------------GD---G--L-P-PPPAHW-K--G-------------------------------------------------------ACEAGVDFPP----SS-C------------------------------------------------------------------------------------------------------GRKLVGARSFSRGF--R------AANGGVGRRV-LAS------------PR-----------------------------------------------------------------------------------------D---R---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATTAA----GAAVA-------------------------------NA------------SL--L-GYA------N-GTA----RGM--APG-A--RVAAY---KV---CW-P----------E-GC--L------------SSD-------------------------------------I--------LAG--------------I-----------DA---AM--------------------A-----D------G----------V----GV-----------------------------------------LSLSLG-----GGS-AP---YF--------------------ED--------------------------TV-------AVGAFG-------AAAA----GV-----F--------------------------------------------------------------------------------------V---------------ACSAG-NA--------GP---------A----GATVANSA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---AT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-GFPAH-VTLGPTGA----RLA-------------GVSLYAG------------------PAQPAMLPMVYGGGRDN------------ASKLCLSGTLDPAS-VRGRIVLCDR-------------GVNARVEKGAVVKAVGGAGMVLANTAASGEELVAD-SHLLPAVAVGKTAGDRIRNY-VYAAAARGNKPMAMLSFGGT----------VLGVRP----AP------VV-AAF-----S--S--------R-GP--N--------------------TV------VPHVL---K--------------------P------------D-----M------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-GWT-----------------------------------------------------------------------------------------------G-AKG---PTGL--AKDG-RR----TRF-NI----------------ISG------TSMSCPHVS----G---------------------------V------------------AA-L----LK----A-------AHPNWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTS------------------------SYT---VDNT-----------------------------------------------------NSSFRDTA------G-S--SPANPFAFGAGHVD---PHKALS----- 666
 667 --------------------------------------------------------SSSN--------------------------G-V--II--------------G--------------------VLD---------------------------T--------------GVWP-E------S-------------R---------S--------------------------------F-D--------------DT---D--M-P-EIPSKW-K--G-------------------------------------------------------ECESGSDFDS----KL-C------------------------------------------------------------------------------------------------------NKKLIGARSFSKGF--QM-----ASGGGFSSKRESVS------------PR-----------------------------------------------------------------------------------------D---V---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------STTAA----GSAVR-------------------------------NA------------SF--L-GYA------A-GTA----RGM--ATR-A--RVATY---KV---CW-S----------T-GC--F------------GSD-------------------------------------I--------LAA--------------M-----------DR---AI--------------------L-----D------G----------V----DV-----------------------------------------LSLSLG-----GGS-AP---YY--------------------RD--------------------------TI-------AIGAFS-------AMER----GV-----F--------------------------------------------------------------------------------------V---------------SCSAG-NS--------GP---------T----RASVANVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---MT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-DFPAF-ANLG-NGK----RLT-------------GV-------------------------------------------------------------------------------------------------------------------------------------------------------KSDSK-PTALLVFKGT----------VLDVKP----SP------VV-AAF-----S--S--------R-GP--N--------------------TV------TPEIL---K--------------------P------------D-----V------I-----------------G-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-GWS-----------------------------------------------------------------------------------------------D-AIG---PTGL--DKDS-RR----TQF-NI----------------MSG------TSMSCPHIS----G---------------------------L------------------AG-L----LK----A-------AHPEWS-----------------------------------------------------------------PSA--------------I---------------------KSAL-------MTT------------------------AYV---LDNT-----------------------------------------------------NAPLHDAA------D-N--SLSNPYAHGSGHVD---PQKALS----- 667
 668 ------------------------------------------------------Y-TYAHAATGVAARLTEEQAAHVAAQPGVLAVD-V--VV--------------G--------------------VLD---------------------------T--------------GIYPIG------R-------------G---------S--------------------------------FLP--------------SS---N--L-G-APPKSF-R--G-------------------------------------------------------GCVSAGAFNA----SAYC------------------------------------------------------------------------------------------------------NAKLVGAKFYYKGY-EE------GLGRAMDEAEESKS------------PL-----------------------------------------------------------------------------------------D---T---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASTAA----GSPVA-------------------------------GA------------SL--F-DYA------R-GQA----VGM--APG-A--RIAAY---KI---CW-A----------N-GC--Y------------DSD-------------------------------------I--------LAA--------------F-----------DE---AV--------------------Y-----D------G----------V----DV-----------------------------------------ISLSVG--AG-SLA-PP---FF--------------------RD--------------------------SI-------AIGAFG-------AMKK----GI-----V--------------------------------------------------------------------------------------V---------------SASAG-NS--------GP---------G----EYTATNIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-EFPAD-VLLG-DGK----VYG-------------GVSLYAG-----------------EPLGSRKLPVVYAADCGS--------------AYCYRGSLDESK-VAGKIVICDR-------------GGNARVEKGAAVKLAGGIGMILANTEDSGEELIAD-AHLVPATMVGQTFGDKIKQY----VKSDPS-PTATIAFRGT----------VIAGSP---SAP------RV-AAF-----S--S--------R-GP--N--------------------YR------AREIL---K--------------------P------------D-----V------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-ESA---PTDL--AIDP-RR----VEF-NI----------------ISG------TSMSCPHVS----G---------------------------L------------------AA-L----LR----Q-------AHPDWS-----------------------------------------------------------------PAA--------------V---------------------KSAL-------MTT------------------------AYN---EDNS-----------------------------------------------------GETIKDLA------T-G--VESTPFVRGAGHVD---PNNALD----- 668
 669 --------------------------------------------------------NYGE--------------------------D-V--IV--------------G--------------------VLD---------------------------T--------------GIWP-E------H-------------P---------S--------------------------------F-S--------------DS---G--L-G-PIPSTW-K--G-------------------------------------------------------ECEIGPDFPA----SS-C------------------------------------------------------------------------------------------------------NRKLIGARAFYRGYLTQ------RNGTKKHAAKESRS------------PR-----------------------------------------------------------------------------------------D---T---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSVVA-------------------------------NA------------SL--Y-QYA------R-GTA----TGM--ASK-A--RIAAY---KI---CW-T----------G-GC--Y------------DSD-------------------------------------I--------LAA--------------M-----------DQ---AV--------------------A-----D------G----------V----HV-----------------------------------------ISLSVG--AS-GSA-PE---YH--------------------TD--------------------------SI-------AIGAFG-------ATRH----GI-----V--------------------------------------------------------------------------------------V---------------SCSAG-NS--------GP---------N----PETATNIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-EFAAN-AITG-D-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KTSDS-PTAKISFLGT----------LIGPSP---PSP------RV-AAF-----S--S--------R-GP--N--------------------HL------TPVIL---K--------------------P------------D-----V------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-GWT-----------------------------------------------------------------------------------------------G-MVG---PTDL--DIDP-RR----VQF-NI----------------ISG------TSMSCPHVS----G---------------------------L------------------AA-L----LR----K-------AHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------VTT------------------------AYD---VENS-----------------------------------------------------GEPIEDLA------T-G--KSSNSFIHGAGHVD---PNKALN----- 669
 670 --------------------------------------------------------NGAT--------------------------N-V--VI--------------G--------------------VID---------------------------T--------------GIYPID------R-------------A---------S--------------------------------FAA--------------DP---S--L-P-PPPSKF-N--G-------------------------------------------------------SCVSTPSFNG----SAYC------------------------------------------------------------------------------------------------------NNKLVGAKFFSKGQRFP----------------PDDS------------PL-----------------------------------------------------------------------------------------D---T---------------------N--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSAVA-------------------------------GA------------AF--F-DYA------R-GKA----VGV--APG-A--RIAAY---KA---CW-E----------A-GC--A------------SID-------------------------------------I--------LAA--------------F-----------DE---AI--------------------A-----D------G----------V----DV-----------------------------------------ISVSLG--AV-GQA-PE---FY--------------------DD--------------------------LT-------AVGAFS-------AVRK----GI-----V--------------------------------------------------------------------------------------V---------------SASAG-NA--------GP---------G----EKTAVNIA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------IN-------R-VFPAD-AVLG-NGE----TFT-------------GTSLYAG-----------------KPLGSAKLPLVYGGDVGS--------------NVCEAQKLNATK-VAGKIVLCDP-------------GVNGRAEKGEAVKLAGGAGAILASTEAFGEQAISS-PHIIAATAVPFAAAKKIKKY----ISMQKS-PVATIIFRGT----------VVGGSP---PSP------RM-ASF-----S--S--------R-GP--N--------------------IH------APEIL---K--------------------P------------D-----V------T-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-ANS---PTEL--ESDK-RR----VKF-NI----------------ISG------TSMSCPHVS----G---------------------------I------------------AA-L----LR----Q-------ARPKWS-----------------------------------------------------------------PAM--------------I---------------------KSAL-------MTT------------------------AYN---MDNS-----------------------------------------------------GSIIGDMS------T-G--KASTPFARGAGHVD---PNRAVD----- 670
 671 ----------------------RHLATTRSPGFLGLLSSPPSAIL-------ADS-DFGS--------------------------D-L--VI--------------A--------------------IID---------------------------T--------------GISP-A------H-------------R---------S--------------------------------F-H--------------DR---G--L-G-PVPPKW-R--G-------------------------------------------------------VCASGPGFPP----NS-C------------------------------------------------------------------------------------------------------NRKLVGARFFSAGY--E------ATSGRMNETAEVRS------------PL-----------------------------------------------------------------------------------------D---KRRAR-----------------D--------------------------------------------------------------------------------------------------------------------------------------------------THG-------VH-R-----------------------------------------------------------------------------------------------------------------R-G--PLRVP---GV---CW-A----------G-GC--F------------DSD-------------------------------------I--------LAA--------------F-----------DA---AV--------------------A-----E------G----------V----DV-----------------------------------------VSLSVG-----GVV-VP---YY--------------------LD--------------------------AI-------AIGAFG-------ATEA----GI-----V--------------------------------------------------------------------------------------V---------------SASAG-NG--------GP---------G----GLTVTNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---TT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------MD-------R-AFPAN-VRLG-NGQ----VLD-------------GVSVYGG-----------------PVLQSGKMYELVYAGTSSGAASASSSGDGYSASMCLDGSLDPAA-VRGKIVVCDR-------------GVNSRAAKGDVVHRAGGVGMVLANGVFDGEGLVAD-CHVLPASAVGAASGEKLRKY-IASSTQQKP-ATGTILFQGT----------HLGVHP----AP------VV-AAF-----S--A--------R-GP--N--------------------PQ------SPEIL---K--------------------P------------D-----L------I-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------N-GVG---PAGI--PSDG-RR----TEF-NI----------------LSG------TSMACPHIS----G---------------------------L------------------AA-L----LK----A-------AHPTWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT------------------------AYI---KDNR-----------------------------------------------------NGTMVDES------T-G--KVADVFDFGAGHVD---PMLAMD----- 671
 672 --------------------------------------------------------DFGS--------------------------D-L--VI--------------G--------------------VID---------------------------T--------------GVWP-E------R-------------P---------S--------------------------------F-D--------------DR---G--L-G-PVPIKW-K--G-------------------------------------------------------QCIASQDFPE----SA-C------------------------------------------------------------------------------------------------------NRKLVGARFFCGGY--E------ATNGKMNETTEFRS------------PR-----------------------------------------------------------------------------------------D---S---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASISA----GRYVF-------------------------------PA------------ST--L-GYA------H-GVA----AGM--APK-A--RLAAY---KV---CW-N----------S-GC--Y------------DSD-------------------------------------I--------LAA--------------F-----------DT---AV--------------------A-----D------G----------V----DV-----------------------------------------ISLSVG-----GVV-VP---YY--------------------LD--------------------------AI-------AIGAFG-------AIDR----GI-----F--------------------------------------------------------------------------------------V---------------SASAG-NG--------GP---------G----ALTVTNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---TT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-DFPAN-VKLG-NGK----MIS-------------GVSVYGG-----------------P-------------------------------------------------------------------GLDSESSK----------------------------------------------------SRSSKH-PTATIVFKGT----------RLGIRP----AP------VV-ASF-----S--A--------R-GP--N--------------------PE------TPEIL---K--------------------P------------D-----V------I-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------D-RIG---PSGV--TSDN-RR----TEF-NI----------------LSG------TSMACPHVS----G---------------------------L------------------AA-L----LK----A-------AHPDWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------ITT------------------------AYT---VDNS-----------------------------------------------------GEPMMDES------T-G--NTSSVMDYGSGHVH---PTKAMD----- 672
 673 --------------------------------------------------------DYGS--------------------------D-V--IV--------------G--------------------VLD---------------------------T--------------GVWP-E------R-------------R---------S--------------------------------L-S--------------DR---N--L-P-PVPARW-R--G-------------------------------------------------------GCDAGAAFPA----SS-C------------------------------------------------------------------------------------------------------NRKLVGARFFSQGH--AAHYGDTAAVAS-NGSVEYMS------------PR-----------------------------------------------------------------------------------------D---A---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ATTAA----GSVSY-------------------------------AA------------SM--E-GYA------P-GVA----KGV--APK-A--RVAAY---KV---CWKG----------A-GC--L------------DSD-------------------------------------I--------LAG--------------F-----------DR---AV--------------------A-----D------G----------V----DV-----------------------------------------ISVSIG--GGNGAT-SP---FY--------------------ID--------------------------PI-------AIGAYG-------AVSR----GV-----F--------------------------------------------------------------------------------------V---------------ATSAG-NE--------GP---------A----AMSVTNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---AT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-SFPAE-IVLG-DGR----RMA-------------GVSLYSG-----------------KPLANNTMLSLYYPGRSG----------GLSASLCMENSIEPSL-VAGKIVICDR-------------GSSPRVAKGMVVKEAGGAAMVLANGEANGEGLVGD-AHVLPACSVGESEGDTLKAY----AANTTN-PTATIVFRGT----------IVGVKP----AP------LV-ASF-----S--A--------R-GP--N--------------------GL------VPEIL---K--------------------P------------D-----F------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------G-ATG---PTGL--ESDP-RR----TEF-NI----------------LSG------TSMACPHAS----G---------------------------A------------------AA-L----LR----S-------AHPGWS-----------------------------------------------------------------PAA--------------I---------------------RSAL-------MTT------------------------AIV---TDNR-----------------------------------------------------GGAVSDEA------EHG--RAATPFDYGAGHIT---LSKALD----- 673
 674 --------------------------------------------------------DYGS--------------------------D-V--II--------------G--------------------VFD---------------------------T--------------GIWP-E------R-------------R---------S--------------------------------F-S--------------DL---N--L-G-PIPKRW-R--G-------------------------------------------------------VCESGARFSP----RN-C------------------------------------------------------------------------------------------------------NRKIIGARFFAKGQ--QA-----AVIGGINKTVEFLS------------PR-----------------------------------------------------------------------------------------D---A---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GRHAF-------------------------------KA------------SM--S-GYA------S-GVA----KGV--APK-A--RIAAY---KV---CWKD----------S-GC--L------------DSD-------------------------------------I--------LAA--------------F-----------DA---AV--------------------R-----D------G----------V----DV-----------------------------------------ISISIG--GGDGIT-SP---YY--------------------LD--------------------------PI-------AIGSYG-------AASK----GI-----F--------------------------------------------------------------------------------------V---------------SSSAG-NE--------GP---------N----GMSVTNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------ID-------R-NFPAD-AILG-DGH----RLR-------------GVSLYAG-----------------VP------------------------------------------------------------------SSHP-------------------------------------------------------------N-PIASIDFRGT----------IVGIKP----AP------VI-ASF-----S--G--------R-GP--N--------------------GL------SPEIL---K--------------------P------------D-----L------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWT-----------------------------------------------------------------------------------------------D-AVG---PTGL--PSDP-RK----TEF-NI----------------LSG------TSMACPHVS----G---------------------------A------------------AA-L----LK----S-------AHPDWS-----------------------------------------------------------------PAV--------------I---------------------RSAM-------MTT------------------------TNL---VDNS-----------------------------------------------------NRSLIDES------T-G--KSATPYDYGSGHLN---LGRAMN----- 674
 675 --------------------------------------------------------GYGR--------------------------G-T--II--------------G--------------------VLD---------------------------T--------------GVWP-E------S-------------P---------S--------------------------------F-D--------------DR---G--M-P-PVPDRW-R--G-------------------------------------------------------ACEAGEHFEA----SN-C------------------------------------------------------------------------------------------------------NRKLVGARFYSKGHRAAN-----HPTDT---AREYAS------------PR-----------------------------------------------------------------------------------------D---A---------------------H--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GSAVA-------------------------------GA------------TV--L-GAGTGEEEDG-GTA----RGV--APG-A--HVAAY---KV---CWFS------------GC--F------------SSD-------------------------------------I--------LAG--------------M-----------DD---AV--------------------R-----D------G----------V----DV-----------------------------------------LSLSLG-----GFP-IP---LF--------------------ED--------------------------SI-------AIGSFR-------ATAR----GV-----S--------------------------------------------------------------------------------------V---------------VCAAG-NN--------GP---------E----PGTVANEA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-RFPAY-VRLG-DGR----VLY-------------GESMYPG-----------------------KLHSKNGGNKEQELELVYAAGGSREAMYCMKGALSSAE-VSGKMVVCDR-------------GITGRADKGEAVREAGGAAMVLANTEINQQEDSVD-VHVLPATLVGYKEAMELKSY-ISSTPR----ATARLVFGGT----------RIGRAR----AP------AV-ALF-----S--S--------R-GP--S--------------------TT------NPSVL---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IA-AWT-----------------------------------------------------------------------------------------------G-SVG---PSGLDGDRDP-RR----SNF-TV----------------LSG------TSMACPHVS----G---------------------------V------------------AA-L----VR----S-------AHPSWS-----------------------------------------------------------------PAM--------------V---------------------RSAI-------MTT------------------------ADA---TDRR-----------------------------------------------------GKPIADDGAFGDGMP----LPADAFAMGAGHVS---PARAVD----- 675
 676 --------------------------------------------------------RFGQ--------------------------G-T--II--------------G--------------------VLD---------------------------T--------------GVWP-E------S-------------P---------S--------------------------------F-D--------------DT---G--M-P-SIPRKW-K--G-------------------------------------------------------ICQEGESFSS----SS-C------------------------------------------------------------------------------------------------------NRKLIGARFFIRGHRVAN-----SPEESPNMPREYIS------------AR-----------------------------------------------------------------------------------------D---S---------------------T--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTVG----GSSVS-------------------------------MA------------NV--L-GNG------A-GVA----RGM--APG-A--HIAVY---KV---CWFN------------GC--Y------------SSD-------------------------------------I--------LAA--------------I-----------DV---AI--------------------Q-----D------K----------V----DV-----------------------------------------LSLSLG-----GFP-IP---LY--------------------DD--------------------------TI-------AIGTFR-------AMER----GI-----S--------------------------------------------------------------------------------------V---------------ICAAG-NN--------GP---------I----ESSVANTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---ST---IG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-RFPAV-VRLA-NGK----LLY-------------GESLYPG-----------------------K-GIKNAG---REVEVIYVTGGDKGSEFCLRGSLPREE-IRGKMVICDR-------------GVNGRSEKGEAVKEAGGVAMILANTEINQEEDSID-VHLLPATLIGYTESVLLKAY-VNATVK----PKARIIFGGT----------VIGRSR----AP------EV-AQF-----S--A--------R-GP--S--------------------LA------NPSIL---K--------------------P------------D-----M------I-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IA-AWP-----------------------------------------------------------------------------------------------Q-NLG---PTGL--PYDS-RR----VNF-TV----------------MSG------TSMSCPHVS----G---------------------------I------------------TA-L----IR----S-------AYPNWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT------------------------ADL---YDRQ-----------------------------------------------------GKAIKDGNK-----------PAGVFAIGAGHVN---PQKAIN----- 676
 677 --------------------------------------------------------SLSS--------------------------D-V--II--------------G--------------------LVD---------------------------T--------------GISP-E------H-------------V---------S--------------------------------F-R--------------DT---H--M-T-PVPSRW-R--G-------------------------------------------------------SCDEGTNFSS----SE-C------------------------------------------------------------------------------------------------------NKKIIGASAFYKGY--E------SIVGKINETTDFRS------------TR-----------------------------------------------------------------------------------------D---A---------------------Q--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GDIVP-------------------------------KA------------NY--F-GQA------K-GLA----SGM--RFT-S--RIAAY---KA---CW-A----------L-GC--A------------STD-------------------------------------V--------IAA--------------I-----------DR---AI--------------------L-----D------G----------V----DV-----------------------------------------ISLSLG-----GSS-RP---FY--------------------VD--------------------------PI-------AIAGFG-------AMQK----NI-----F--------------------------------------------------------------------------------------V---------------SCSAG-NS--------GP---------T----ASTVSNGA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---MT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------Y-------------------------------------------------------------------------------------TD-------R-TFPAI-VRIG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGAAN-ATASVRFRGT----------AYGAT-----AP------MV-AAF-----S--S--------R-GP--S--------------------VA------GPEIA---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-GWS-----------------------------------------------------------------------------------------------P-FSS---PSLL--RSDP-RR----VQF-NI----------------ISG------TSMACPHIS----G---------------------------I------------------AA-L----IK----S-------VHGDWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------MTT------------------------ARI---TDNR-----------------------------------------------------NRPIGDRG------AAGAESAATAFAFGAGNVD---PTRAVD----- 677
 678 ---------------------------------------------------------YGE--------------------------D-V--IV--------------G--------------------VVD---------------------------T--------------GVWP-E------S-------------A---------S--------------------------------Y-R--------------DD---G--L-P-PVPARW-K--G-------------------------------------------------------FCESGTAFDA----AQVC------------------------------------------------------------------------------------------------------NRKLVGARKFNKGL----------IA-NSNVTIAMNS------------PR-----------------------------------------------------------------------------------------D---T---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GSPVS-------------------------------GA------------SY--F-GYA------R-GTA----RGM--APR-A--RVAVY---KA---LW-D----------E-GT--Y------------QSD-------------------------------------I--------LAA--------------M-----------DQ---AI--------------------A-----D------G----------V----DV-----------------------------------------LSLSLG-----LNN-VP---LY--------------------KD--------------------------PI-------AIGAFA-------AMQR----GV-----F--------------------------------------------------------------------------------------V---------------STSAG-NA--------GP---------D----FGLLHNGT---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---LT---VA--S------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-EFSSI-VKLG-DGT----TVI-------------GESLYLG-----------------GSPAGTFASTALVYLRAC------------------DNDTLLSM-NRDKVVLCEA-------------AGDSLGSAISAAQSAKVRAALFLSNDSFRE--LYE-HLEFPGVILSPQDAPALLHY-IQRSRA----PKASIKFKVT----------VVDTKP----AP------AV-ATY-----S--S--------R-GP--S--------------------GS------CPAVL---K--------------------P------------D-----L------L-----------------A-----P-------------G-----------------SL--------------------------------I------------------------------------------------------------------LA-SWS-----------------------------------------------------------------------------------------------E-NAT---VGTV--GSQT-LY----GKF-NI----------------ISG------TSMSCPHAS----G---------------------------V------------------AA-L----LR----A-------VHPDWS-----------------------------------------------------------------PAA--------------V---------------------RSAL-------MTT------------------------ATA---ADNT-----------------------------------------------------FSPIKDMG------RDN--RAATPLAMGSGHID---PTRALD----- 678
 679 --------------------------------------------------------DYGK--------------------------D-V--IV--------------G--------------------LVD---------------------------T--------------GIWP-E------S-------------K---------S--------------------------------Y-T--------------DN---G--M-T-EVPSRW-K--G-------------------------------------------------------ECESGTQFNS----S-LC------------------------------------------------------------------------------------------------------NKKLIGARYFNKGL----------IATNPNITILMNS------------AR-----------------------------------------------------------------------------------------D---T---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GSHVE-------------------------------SV------------SY--F-GYA------P-GAA----TGM--APK-A--HVAMY---KA---LW-D----------E-GT--M------------LSD-------------------------------------I--------LAA--------------I-----------DQ---AI--------------------E-----D------G----------V----DI-----------------------------------------LSLSLG-----IDG-RA---LY--------------------DD--------------------------PV-------AIATFA-------AMEK----GI-----F--------------------------------------------------------------------------------------V---------------STSAG-NE--------GP---------D----GQTLHNGT---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---LT---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-EFIGT-LTLG-NGV----SVT-------------GLSLYPG-----------------NSSS---SESSIVFLKTC------------------LEEKELEK-NANKIAICYD-------------TNGSISDQLYNVRNSKVAGGVFITNYTDLE--FYL-QSEFPAVFLNFEDGDKVLEY-IKNSHS----PKARLEFQVT----------HLGTKP----AP------KV-ASY-----S--S--------R-GP--S--------------------QS------CPFIL---K--------------------P------------D-----L------M-----------------A-----P-------------G-----------------AL--------------------------------I------------------------------------------------------------------LA-SWP-----------------------------------------------------------------------------------------------Q-KSP---ATKI--NSGE-LF----SNF-NI----------------ISG------TSMSCPHAA----G---------------------------V------------------AS-L----LK----G-------AHPKWS-----------------------------------------------------------------PAA--------------I---------------------RSAM-------MTT------------------------ADA---LDNT-----------------------------------------------------QRPIRDIG------RNN--NAASPLAMGAGHIN---PNKALD----- 679
 680 ----------------------------------------------------------------------------------------V--IV--------------G--------------------MID---------------------------T--------------GVWP-E------S-------------A---------S--------------------------------F-D--------------DA---G--M-S-PAPSKW-R--G-------------------------------------------------------TCEPGQAFTA----A-MC------------------------------------------------------------------------------------------------------NRKLIGARYFNKGL----------VAANPGITLTMNS------------TR-----------------------------------------------------------------------------------------D---S---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------SSTAA----GSFVK-------------------------------CA------------SF--F-GYG------L-GTA----RGV--APR-A--HVAMY---KV---IF-D----------E-GR--Y------------ASD-------------------------------------V--------LAG--------------M-----------DA---AI--------------------A-----D------G----------V----DV-----------------------------------------ISISMG-----FDG-VP---LY--------------------ED--------------------------PV-------AIAAFA-------AMER----GI-----L--------------------------------------------------------------------------------------V---------------SSSAG-NA--------GP---------R----PRSLHNGI---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---LT---VA--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------RKMFSGT-VTYG-NTT--QWTIA-------------GVTTYPA-----------------NAWVVDMKLVYNDAVSAC------------------SSAASLAN-VTTSIVVCAD-------------TG-SIDEQINNVNEARVAAAIFITEVSSFE----D-TMPLPAMFIRPQDAQGLLSY-INSTAI----PIASMSFQQT----------ILGTRP----AP------VV-TAY-----S--S--------R-GP--S--------------------RS------YPGVL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------NS--------------------------------I------------------------------------------------------------------LA-SFA-----------------------------------------------------------------------------------------------P--VG---PTGL--IGQTSLR----SEF-YV----------------ASG------TSMACPHAS----G---------------------------V------------------AA-L----LR----A-------AHPDWS-----------------------------------------------------------------PAM--------------I---------------------KSAM-------MTT------------------------ATT---IDNT-----------------------------------------------------FRPIVDAGSIVSGNGSA--AAASPLAMGSGHVS---PNSAMD----- 680
 681 --------------------------------------------------------GLGQ--------------------------D-V--IV--------------A--------------------VLD---------------------------S--------------GIWP-E------S-------------A---------S--------------------------------F-Q--------------DD---G--M-P-EIPKRW-K--G-------------------------------------------------------ICKPGTQFNA----S-MC------------------------------------------------------------------------------------------------------NRKLIGANYFNKGI----------LANDPTVNITMNS------------AR-----------------------------------------------------------------------------------------D---T---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-C-----------------------ASITA----GNFAK-------------------------------GV------------SH--F-GYA------P-GTA----RGV--APR-A--RLAVY---KF---SF-N----------E-GT--F------------TSD-------------------------------------L--------IAA--------------M-----------DQ---AV--------------------A-----D------G----------V----DM-----------------------------------------ISISYG-----YRF-IP---LY--------------------ED--------------------------AI-------SIASFG-------AMMK----GV-----L--------------------------------------------------------------------------------------V---------------SASAG-NR--------GP---------G----IGSLNNGS---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---LC---VA--S------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------H-------------------------------------------------------------------------------------TD-------R-TFKNS-VT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PTATITFQET----------YLDTKP----AP------VV-AAS-----S--A--------R-GP--S--------------------RS------YLGIS---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------VL--------------------------------I------------------------------------------------------------------LA-AYP-----------------------------------------------------------------------------------------------P-NVF---ATSI--GTNILLS----TDY-IL----------------ESG------TSMAAPHAA----G---------------------------I------------------AA-M----LK----A-------AHPEWS-----------------------------------------------------------------PSA--------------I---------------------RSAM-------MTT------------------------ADP---LDNT-----------------------------------------------------RKPIKDS-------DNN--KAATPLDMGAGHVD---PNRALD----- 681
 682 ---HRDRVYHTQTTRSPGFIGLHADFGAWPDS------------------------EFGD--------------------------N-V--II--------------G--------------------VVD---------------------------T--------------GISP-A------S-------------S---------S--------------------------------F-N--------------DS---G--L-G-PVRPGW-K--G-------------------------------------------------------KCVDAEGFSA----SS-C------------------------------------------------------------------------------------------------------NRKLVGDKVF------------------INEEDGIFT------------PR-----------------------------------------------------------------------------------------D---K---------------------L--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASTAA----GSKVQ-------------------------------GA------------NM--L-GFS------Q-GSA----SGV--ARM-A--RIAMY---KA---CN-T----------L-TC--T------------ESA-------------------------------------I--------VAA--------------I-----------DA---AV--------------------S-----D------G----------V----DI-----------------------------------------ISLSLG--K--LQD-PA---FY--------------------DD--------------------------MV-------AVARFG-------ATRR----GV-----F--------------------------------------------------------------------------------------V---------------VFAGG-NS--------GP---------I----ASTVSNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---TT---VG--A------------------------------A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGF-----S--S--------R-GP--N--------------------PL------APELL---K--------------------P------------D-----V------V-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-AWP-----------------------------------------------------------------------------------------------G-DLS---PTNN--GIDP-RR----VEY-NI----------------MSG------TSMACPHVA----G---------------------------V------------------AA-L----IR----K-------RHGDWT-----------------------------------------------------------------PAM--------------V---------------------RSAM-------MTT------------------------ADT---LDMN-----------------------------------------------------GRGIIDNG-------SG--NDTTPLEAGAGLV--------------- 682
 683 --------------------------------------------------------GYGE--------------------------D-T--II--------------A--------------------NLD---------------------------T--------------GVWP-E------S-------------K---------S--------------------------------F-S--------------DE---G--Y-G-AVPARW-K--G-------------------------------------------------------RCHKD----VP------C------------------------------------------------------------------------------------------------------NRKLIGARYFNKGYLAYT-G---L-PSN----ASYET------------CR-----------------------------------------------------------------------------------------D---H---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------LSTAA----GNFVP-------------------------------GA------------NV--F-GIG------N-GTA----SGG--SPK-A--RVAAY---KV---CWPP--V-----DGA-EC--F------------DAD-------------------------------------I--------LAA--------------I-----------EA---AI--------------------E-----D------G----------V----DV-----------------------------------------LSASVG-----GDA-GD---YM--------------------SD--------------------------GI-------AIGSFH-------AVKN----GV-----T--------------------------------------------------------------------------------------V---------------VCSAG-NS--------GP---------K----SGTVSNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---IT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------MD-------R-EFQAF-VELKN-GQ----SFK-------------GTSLSKP----------------------------------------------------------------------------------------------------------------------------LPS-----------------STKD----PKGYIKAPTA----------TLNTKP----AP------FM-ASF-----S--S--------R-GP--N--------------------TI------TPGIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------IA-AFT-----------------------------------------------------------------------------------------------E-ATG---PTDL--DSDN-RR----TPF-NT----------------ESG------TSMSCPHIS----G---------------------------V------------------VG-L----LK----T-------LHPHWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------MTT------------------------SRT---RNNR-----------------------------------------------------RKPMVDESF----------KKANPFSYGSGHVQ---PNKAAH----- 683
 684 --------------------------------------------------------RFGE--------------------------D-T--II--------------A--------------------NLD---------------------------T--------------GVWP-E------S-------------K---------S--------------------------------F-R--------------DE---G--L-G-PIPSRW-K--G-------------------------------------------------------ICQNQKDATFH------C------------------------------------------------------------------------------------------------------NRKLIGARYFNKGYAAAV-G-----HLN----SSFDS------------PR-----------------------------------------------------------------------------------------D---L---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------LSTAA----GDFVP-------------------------------GV------------SI--F-GQG------N-GTA----KGG--SPR-A--RVAAY---KV---CWPP--V-----KGN-EC--Y------------DAD-------------------------------------V--------LAA--------------F-----------DA---AI--------------------H-----D------G----------A----DV-----------------------------------------ISVSLG-----GEP-TS---FF--------------------ND--------------------------SV-------AIGSFH-------AAKK----RI-----V--------------------------------------------------------------------------------------V---------------VCSAG-NS--------GP---------A----DSTVSNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------Q---IT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-EFASN-LVLGN-GK----HYK-------------GQSLSST-----------------ALTQTKK-----------------------------------------------------------------------------------------------------PIAHITPS---------------------------RT----------DLGLKP----AP------VM-ASF-----S--S--------K-GP--S--------------------IV------APQIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VS--------------------------------V------------------------------------------------------------------IA-AYT-----------------------------------------------------------------------------------------------G-AVS---PTNE--QFDP-RR----LLF-NA----------------ISG------TSMSCPHIS----G---------------------------I------------------AG-L----LK----T-------RYPSWS-----------------------------------------------------------------PAA--------------I---------------------RSAI-------MTT------------------------ATT---MDDI-----------------------------------------------------PGPIQNATN----------MKATPFSFGAGHVQ---PNLAVN----- 684
 685 KEKAQDAIFYSYTKHINGFAATLEEEEAMEISKHPSVISVFPNRA-------HK--LFGQ--------------------------G-V--II--------------G--------------------NLD---------------------------T--------------GVWP-E------A-------------G---------S--------------------------------F-D--------------DD---G--M-G-PVPARW-R--G-------------------------------------------------------VCQNQ----VR------C------------------------------------------------------------------------------------------------------NRKLIGAQYFNKGYLATLAG-----EAA----ASPAT------------AR-----------------------------------------------------------------------------------------D---T---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------LSTAA----GRFVP-------------------------------GA------------NL--F-GYG------N-GTA----KGG--APG-A--HVAAY---KV---CWHP--R-----AGS-EC--A------------DAD-------------------------------------I--------LAA--------------F-----------DA---AI--------------------H-----D------G----------V----DV-----------------------------------------LSVSLG-----TSP-VD---YF--------------------RE--------------------------GV-------AIGSFH-------AVMN----GI-----A--------------------------------------------------------------------------------------V---------------VASAG-NA--------GP---------R----AGTVSNTA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------L---FT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-EFPAY-VVFANHSR----RIK-------------GQSLSPD-----------------RLPDNKHYPLISSEEAKA------TNATAQQARFCMEGSLDKTK-VEGKIVVCMR-G-----------KA-PRVEKGQSVHRAGGVGLVLANDEATGNEMIAD-AHVLPATHVTYSDGVELLAY-IEATTF----ASGYITSPNT----------ALETKP----AP------FM-AAF-----S--S--------Q-GP--N--------------------IV------TPQIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VS--------------------------------I------------------------------------------------------------------LA-AFT-----------------------------------------------------------------------------------------------G-LVG---PTSL--PFDS-RR----VLF-NS----------------ESG------TSMSCPHVS----G---------------------------I------------------AG-L----LK----A-------LHPDWS-----------------------------------------------------------------PAA--------------I---------------------KSAI-------MTT------------------------ARV---QDNT-----------------------------------------------------RKPMSNSSF----------LRATPFGYGAGHVQ---PNRAA------ 685
 686 KDKAREAIFYSYTKHINGFAANLNAAEAAQLARLPEVVSVFPNRA-------Q---QFGE--------------------------G-I--II--------------G--------------------NID---------------------------T--------------GVWP-E------S-------------E---------S--------------------------------F-R--------------DH---G--L-G-SVPKNW-K--G-------------------------------------------------------TCEKGQDDKFH------C------------------------------------------------------------------------------------------------------NGKLIGARFFNKGYASGV-G---APSDD----PTFNS------------PR-----------------------------------------------------------------------------------------D---N---------------------G--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------LSTAA----GAPSP-------------------------------GA------------SV--F-GLG------N-GTA----TGG--SPR-A--RVAGY---RV---CFKP--V-----NGS-SC--F------------EAD-------------------------------------I--------LAA--------------F-----------DA---AI--------------------H-----D------G----------V----HV-----------------------------------------LSVSLG---GVGDR-YD---YF--------------------ED--------------------------SI-------AIGSFH-------AVRH----GI-----T--------------------------------------------------------------------------------------V---------------VCSAG-NS--------GP---------K----PSKISNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---FT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-KFSSD-VVFN--GT----KIK-------------GESLSSN-----------------TLNQKTPYPMIDSTQAAA------PGRSEDEAQLCLKGSLDPKK-VHGKIVVCLR-G-----------DN-ARVAKGEVVHEAGGAGMVLANDASSGNEIISD-PHVLPATHVGFHDGLLLFSY-LKIDKA----PVGMIEKPTT----------SVYTKP----AP------YM-AAF-----S--S--------Q-GP--S--------------------PV------NPEIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------IA-AWT-----------------------------------------------------------------------------------------------R-ATS---PTEL--DNDK-RR----VAY-NA----------------ISG------TSMSCPHVA----G---------------------------I------------------AG-L----IK----A-------LHPDWS-----------------------------------------------------------------PAA--------------V---------------------RSAL-------MTT------------------------AIE---VDNK-----------------------------------------------------GQQILNSSF----------AAAGPFERGAGHVW---PSRS------- 686
 687 REKARDAIFYSYTKNINGFAATLEPHVAAAIAKQPGVVSVFPN-------------RYGE--------------------------D-T--II--------------A--------------------NLD---------------------------S--------------GVWP-E------S-------------L---------S--------------------------------F-N--------------DG---E--M-G-PIPDDW-K--G-------------------------------------------------------ICQNEHDPKFK------C------------------------------------------------------------------------------------------------------NSKLIGARYFNKGYAAAA-G---VPPVA----PSLNT------------PR-----------------------------------------------------------------------------------------D---D---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------LSTAG----GSAVN-------------------------------GA------------NA--F-GYG------N-GTA----RGG--SPR-A--RVAAY---RV---CFEPA-V-----DDT-EC--F------------DAD-------------------------------------I--------LAA--------------F-----------EA---AI--------------------A-----D------G----------V----HV-----------------------------------------ITASVG-----GDP-QD---FR--------------------DD--------------------------AV-------ALGSLH-------AVKA----GI-----T--------------------------------------------------------------------------------------V---------------ACSAS-NS--------GP---------D----PGTVTNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---IT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------TD-------R-DFPAY-VVFNR--T----RVP-------------GQSLSQA-----------------WLRGKAFYPLVASTDVVA------NGSTADDAQVCALGSLDAAK-VKGKIVVCIR-G-----------AN-RRVEKGETVRRAGGAGMVLVNDEVGGTTVIAD-PHVLPALHITYADGLQLLAY-IKSTSA----PSGFISKART----------KTGTKP----AP------VM-AAF-----S--S--------Q-GP--N--------------------VL------QPEIL---K--------------------P------------D-----V------T-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------IA-AWS-----------------------------------------------------------------------------------------------G-MAA---PSDR--PWDQ-RR----VAF-SI----------------QSG------TSMSCPHIA----G---------------------------I------------------AG-L----VK----T-------LHPDWS-----------------------------------------------------------------PSA--------------I---------------------KSAI-------MTT------------------------ATA---TDMD-----------------------------------------------------RRPILNPFR----------APSTPFGYGAGHVF---PQRALD----- 687
 688 KQLAKDAIFYSYTKNINGFAAYLDEEVAAEMAKHPDVVTVMPSKM-------LK--LFGQ--------------------------N-V--II--------------A--------------------NLD---------------------------S--------------GVWP-E------S-------------S---------S--------------------------------F-S--------------DE---G--M-A-EVPKRW-R--G-------------------------------------------------------SCPGSAKYAVP------C------------------------------------------------------------------------------------------------------NRKLIGARYFNKDMLLSN-------PAA----VDGNW------------AR-----------------------------------------------------------------------------------------D---T---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------LSTAG----GRFVP-------------------------------RA------------SL--F-GYA------N-GTA----KGG--APR-A--RVAAY---KV---CWAG------------EC--A------------TAD-------------------------------------V--------LAG--------------F-----------ES---AV--------------------H-----D------G----------A----DV-----------------------------------------ISVSFGQEAPLADT-KS---FF--------------------HE--------------------------PV-------TLGSLH-------AAIH----GV-----S--------------------------------------------------------------------------------------V---------------VCSAG-NS--------GP---------F----DDTVVNGA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---TT---VA--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------VD-------R-DFPNQ-ITLGN-NI----HMK-------------GMSLESS-----------------DLHSNKLFPMVNASGAAL------PNCSAELASNCAMGCLDPPK-VKGKIVVCVR-G-----------GDIPRVMKGMAVLSAGGAGMILANGKMDGDDVEAD-PHVLPATMITYSEAVSLYKY-MASSAY----PVANISPSKT----------ELGVKN----SP------SM-AAF-----S--S--------R-GP--S--------------------GT------LPFVL---K--------------------P------------D-----I------A-----------------A-----P-------------G-----------------VD--------------------------------I------------------------------------------------------------------LA-AFT-----------------------------------------------------------------------------------------------E-YVS---PTEV--AADK-RR----SEY-AI----------------LSG------TSMACPHVS----G---------------------------V------------------IG-L----LK----A-------ARPEWS-----------------------------------------------------------------PAA--------------M---------------------RSAI-------MTT------------------------ART---QDNT-----------------------------------------------------GAPMRDSNG----------KEATAFAYGAGNVH---PNRAVD----- 688
 689 --------------------------------------------------------KYGQ--------------------------G-V--II--------------A--------------------NVD---------------------------T--------------GVSP-T------S-------------A---------S--------------------------------F-R--------------ND---G--L-M-VDPSKW-RHRD-------------------------------------------------------TCDAGNDPTFQ------C------------------------------------------------------------------------------------------------------NNKLIGARFFSKAVQVESLH---HGNSSRLNRTDLNS------------PR-----------------------------------------------------------------------------------------D---H---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------LSTAG----GGFVD-------------------------------GA------------GA--F-GHG------A-GTA----KGG--SPR-A--RVASY---KA---CFLP----------N-AC--S------------GID-------------------------------------I--------LKA--------------V-----------VT---AV--------------------D-----D------G----------V----DV-----------------------------------------LSLSLG-----EPP-AH---YI--------------------TG--------------------------LM-------ELGALY-------AVRK----GV-----V--------------------------------------------------------------------------------------V---------------VAAAG-ND--------GP---------E----PGSVTNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---FT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-DFPAL-VTFRVTTTNTTKTIK-------------GRSLSDS-----------------TVPAGQEHPMISGEKASA------TEST-KNSTLCLPGSLDQAK-VKGKIVVCTR-G-----------VN-GRMQKGQVVKEAGGIGMVLCNDESSGDSTDAD-PHVIPAAHCSFSQCKDLLTY-LQSE-S----PVGDITAMDA----------ELGVKP----AP------VM-AAF-----S--S--------R-GP--N--------------------TI------TPQIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VG--------------------------------V------------------------------------------------------------------IA-AYG-----------------------------------------------------------------------------------------------ELEAT---ATDL--PS-----------Y-NI----------------LSG------TSMACPHVA----G---------------------------I------------------AG-L----LK----T-------KYPEWS-----------------------------------------------------------------PAM--------------I---------------------KSAI-------MTT------------------------A------DNY-----------------------------------------------------S-QIQEETG----------AAATPLGFGAGHVN---PLKALD----- 689
 690 --------------------------------------------------------KYGQ--------------------------G-V--VI--------------A--------------------NVD---------------------------T--------------GVWP-T------S-------------A---------S--------------------------------F-G--------------ND---G--L-E-A-PWRW-RFGD-------------------------------------------------------RCDRGKDPTFR------C------------------------------------------------------------------------------------------------------NNKLIGARFFSEAVQVESFQ---DGTSGKLNKTDLSS------------PR-----------------------------------------------------------------------------------------D---Y---------------------V--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------LSTAG----GGFVP-------------------------------NA------------GV--FGGHG------N-GTA----KGG--SPR-A--YVASY---KA---CFLP----------D-TC--S------------SMD-------------------------------------V--------LTA--------------I-----------VT---AV--------------------H-----D------G----------V----DV-----------------------------------------LSLSIG-----APP-SD---LF--------------------TD--------------------------LL-------AIGALY-------AVRN----GV-----V--------------------------------------------------------------------------------------V---------------VASAG-ND--------GP---------V----PGSVSNVA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------M---LT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MD-------R-DFPAQ-VTFGATNT----TIK-------------GRSLSNS-----------------TLAAGEKYPMISGEKASA------TEST-DNSTLCFPGSLDQAK-VKGKIVVCTR-G-----------VN-GRMEKGQVVKEAGGVGMVLCNDESTGESTVAD-PHVIPAAHCSFSQCKDLFAY-LQSESS----PVGFITAMDA----------QLGVKP----AP------VM-AAF-----S--S--------R-GP--N--------------------TI------TPQIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------VE--------------------------------V------------------------------------------------------------------IA-AYS-----------------------------------------------------------------------------------------------E-GVS---ATGL--PSDD-RR----APY-NI----------------LSG------TSMSCPHVA----G---------------------------I------------------AG-L----LK----A-------KYPKWS-----------------------------------------------------------------PDM--------------I---------------------KSAI-------MTT------------------------A------NNN-----------------------------------------------------SGEIQEESG----------AAATPFGYGAGHVN---PLKALD----- 690
 691 --------------------------------------------------------KHGD--------------------------G-V--IV--------------G--------------------LID---------------------------S--------------GVWP-E------S-------------R---------S--------------------------------F-D--------------DK---G--M-G-PIPESW-K--G-------------------------------------------------------ICQTGVAFN-----SSHC------------------------------------------------------------------------------------------------------N------RYYARGYERY------YGPFNAEANKDFLS------------PR-----------------------------------------------------------------------------------------D---A---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASTAV----GRRVD-------------------------------GV------------SA--LGGIA------M-GTA----SGG--ASL-A--RLAVY---KA---CWAV--PNKEKYATN-TC--F------------DED-------------------------------------M--------LAA--------------F-----------DD---AI--------------------A-----D------G----------V----NV-----------------------------------------ISISIG----TVEP-HT---YL--------------------ED--------------------------GI-------AIGALH-------AVKR----DI-----V--------------------------------------------------------------------------------------V---------------AASAG-ND--------GP---------A----RETLSNPA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------LD-------R-FFVGR-LELG-DGY----VFE-------------SDSLTTL-------------------------KMDNYAPLVYAPDVVVPGVSRNDAMLCLPNALSPDH-VRGKVVLCLRGY-----------GSGSTIGKGLEVKRAGGVGMILANSRDNDAFDVE--SHFVPTALVFSSTVDRILDY-IYNTYE----PVAFIKPAETVLYRNQPEDSVYPYKP----AP------FM-TSF------------------------------------------------------------L--------------------P------------D-----I------I-----------------A-----P-------------G-----------------LN--------------------------------I------------------------------------------------------------------LA-AWS-----------------------------------------------------------------------------------------------G-ADS---ASKDSIDRRV-------LDY-NL----------------DSG------TSMSCPHVA----G---------------------------A------------------IA-L----LK----S-------MHPTWS-----------------------------------------------------------------SAA--------------I---------------------RSAL-------MTT------------------------ASM---TNED-----------------------------------------------------NEPIQDYDG----------SPANPFALGSRHFR---PTKAAS----- 691
 692 --------------------------------------------------------KHGD--------------------------G-I--IV--------------G--------------------VLD---------------------------S--------------GVWP-E------S-------------K---------S--------------------------------F-N--------------DK---G--M-G-PVPKSW-K--G-------------------------------------------------------ICQTGVAFN-----SSHC------------------------------------------------------------------------------------------------------NRKIIGARYYVKGYERY------YGAFNATANKDFLS------------PR-----------------------------------------------------------------------------------------D---P---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASTAV----GRRVL-------------------------------GA------------SA--LGGFA------K-GSA----SGG--APL-A--RLAIY---KA---CWAK--PNAEKVEGN-IC--L------------EED-------------------------------------M--------LAA--------------I-----------DD---AI--------------------A-----D------G----------V----HV-----------------------------------------ISISIG----TTEP-FP---FT--------------------QD--------------------------GI-------AMGALH-------AVKR----NI-----V--------------------------------------------------------------------------------------V---------------AASAG-NS--------GP---------K----PGTLSNLA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---IT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------LD-------R-AFVGG-LVLG-NGY----TIK-------------TDSITAF-------------------------KM----------------------------------------------------------------------------------------------------------KTDK----------N----PKAFIKPGKT----------VYKYQA----AP------SM-TGF-----S--S--------R-GP--N--------------------VV------DPNIL---K--------------------P------------D-----I------T-----------------A-----P-------------G-----------------LY--------------------------------I------------------------------------------------------------------LA-AWS-----------------------------------------------------------------------------------------------G-ADS---PSKMSVDQRV-------AGY-NI----------------YSG------TSMSCPHVA----G---------------------------A------------------IA-L----LK----A-------IHPKWS-----------------------------------------------------------------SAA--------------I---------------------RSAL-------MTT------------------------AWM---TNDK-----------------------------------------------------KKPIQDTTG----------LPANPFALGSGHFR---PTKAAD----- 692
 693 --------------------------------------------------------NYGA--------------------------G-I--VI--------------G--------------------IID---------------------------T--------------GIWP-D------S-------------P---------S--------------------------------F-H--------------DD---G--V-G-SVPSKW-K--G-------------------------------------------------------AC----EFNS----SSLC------------------------------------------------------------------------------------------------------NKKLIGAKVFNKGLFAN------NPDLRETKIGQYSS------------PY-----------------------------------------------------------------------------------------D---T---------------------I--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------AAIAA----GNHVK-------------------------------NA------------SY--F-SYA------Q-GTA----SGI--APH-A--HLAIY---KA---AWEE------------GI--Y------------SSD-------------------------------------V--------IAA--------------I-----------DQ---AI--------------------R-----D------G----------V----HV-----------------------------------------ISLSLGLSFEDDDD-NDGFGLE--------------------ND--------------------------PI-------AVASFA-------AIQK----GV-----F--------------------------------------------------------------------------------------V---------------VTSGG-ND--------GP---------Y----YWSLINGA---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------I---MT---VG--A------------------------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------IG-------R-QFQGT-LTFG-NRV----SFS-------------FPSLFPG------------------EFPSVQFPVTYIESGSV-----------------------ENKTLANRIVVCN--------------ENINIGSKLHQIRSTGAAAVVLITDKLLEEQDTI--KFQFPVAFIGSKHRETIESYASSNKNN----ATAKLEFRKT----------VIGTKP----AP------EV-GTY-----S--S--------R-GP--F--------------------TS------FPQIL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------TL--------------------------------I------------------------------------------------------------------LS-AWP-----------------------------------------------------------------------------------------------S-----------VEQITGTRALPLFSGF-NL----------------LTG------TSMAAPHVA----G---------------------------V------------------AA-L----IK----Q-------VHPNWS-----------------------------------------------------------------PSA--------------I---------------------KSAI-------MTT------------------------ALT---LD-----------------------------------------------------------------------------NPLAVGAGHVS---TNKVLN----- 693
 694 ----------------------------------------------------------GE--------------------------G-V--IF--------------G--------------------VLD---------------------------S--------------GVWP-E------H-------------P---------S--------------------------------F-S--------------DPDPLGKPYAP-PPPAPG-NPGG-----------------------------------------------------LRACNFGSATPGDAPFT--C------------------------------------------------------------------------------------------------------NNKLIGSYRFMSAYDFFV----------GTQPYEFRS------------GR-----------------------------------------------------------------------------------------D---D---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASTAA----GNRGV-------------------------------PA------------SD----GSR------VFGTI----SGI--APR-A--YIVNY---KV---CGEL------------GC--F------------TTD-------------------------------------S--------AAA--------------V-----------QQ---AI--------------------R-----D------G----------V----HV-----------------------------------------INFSIS-----GGT-NP----Y--------------------SD--------------------------IA-------SLAFLD-------AYNA----GI-----L--------------------------------------------------------------------------------------V---------------SASAG-NS--------GP---------A----PDTVNHRE---------------------------------------------------------------------------------------------------------------------------------------P-W--------------------------------V---AT---VG--A------------------------------S------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------SD-------R-SYLSTLTVQGSSGT---FTAV-------------GASSGAGISTPAPVVVNTTDPLCLNPAAAGT--------------------------------------FTGQIVVCER-------------GIIARVAKSANVAAGGAIGMILYNPTPSSLDAD---FHSIPTVHIQNTDGSALLAF---LTAN----PGATATFTPG--------------------APGPIQGDVM-AGF-----S--S--------R-GG--P--------------------GQ------TLGIS---K--------------------P------------D-----V------T-----------------A-----P-------------G-----------------VN--------------------------------I------------------------------------------------------------------LA-GYT-----------------------------------------------------------------------------------------------AIEYGQAVP-----------------QF-AF----------------LSG------TSMSSPHNA----G---------------------------A------------------AI-L----LK----W-------LNPTWT-----------------------------------------------------------------PGQ--------------I---------------------KSAL-------MTS------------------------AKAAGVYKED-----------------------------------------------------GV-----------------TRFTPFDAGSGRID-------------- 694
 695 ------W----VKEG-------------------------------------GFE-IAGE--------------------------G-V--II--------------G--------------------FID---------------------------T--------------GIDP-N------H-------------P---------S--------------------------------F---------------------N----------------DND-SKRSYPIP---KHFSGVCEVTPDFPSGSCNKKLIGARHFA----------QSA----------------------------------------------------------------------------------------------------------------------------------------------VTRGIFNSSEDYAS------------PF-----------------------------------------------------------------------------------------D---G---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASVAA----GNH-G-------------------------------VP------------VIVSNHNFGYAS-------------GI--APR-A--FISVY---KA---LYKS----------F-GG--F------------AAD-------------------------------------V--------VAA--------------I-----------DQ---AA----------------QD---------------G----------V----DI-----------------------------------------LSLSITPNRK--PP-GV-ATFF---------------------N--------------------------PIDM-----ALLS-A--------VKA----GI-----F--------------------------------------------------------------------------------------V---------------VQAAG-NT--------GP---------APKTMS---SFSPWIFTVGASSHDRVYSNSLTLGNNVTIPGMGFAIPTDSGKMYKMISAFHALNNSTS-VDKDMYVGECQDYENFDQDRVSGKLLICSYSARFVLGLSTIKQALDVAKNLSATGVIFY------IDPYVLGFEINPT-P-M--D-M----PG---------------------I---II---PS--V------------------------------E-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------KT-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKYYNSSIQRDVTTKEIVSFGAVAAIEGGLNANFSN---RAP------KV-MYY-----S--A--------R-G---P--------------------DPEDNSFNDADVL---K--------------------P------------N-----L------V-----------------A-----P-------------G-----------------NS--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------SASTDST--E----FEGE--------KF-AM----------------MSG------TSMAAPHVA----G---------------------------V------------------AA-L----IK----Q-------SYPQFT-----------------------------------------------------------------PST--------------I---------------------SSAL-------STT-------------------------AL------------------------------------------------------------------------LNDNKGSPIMAQRTYSNPDQSLYTATPSDMGSGFV 695
 696 ------W----VKEG-------------------------------------GYE-TAGE--------------------------G-I--VI--------------G--------------------FID---------------------------T--------------GIDP-T------H-------------P---------S--------------------------------F---------------------N----------------GTDTSQRQYPIP---NHFSGVCEVTPDFPSGSCNRKLVGARHFA----------QSA----------------------------------------------------------------------------------------------------------------------------------------------ITRGIFNSSEDYAS------------PF-----------------------------------------------------------------------------------------D---G---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAA----GNH-G-------------------------------VS------------AVVSGHNFGSAS-------------GI--APR-A--HISVY---KA---LYKS----------F-GG--F------------AAD-------------------------------------V--------VAA--------------I-----------DQ---AA----------------QD---------------G----------V----DI-----------------------------------------LSLSITPNRR--PP-GV-ATFF---------------------N--------------------------PLDM-----AMLS-A--------VKA----GI-----F--------------------------------------------------------------------------------------V---------------VQAAG-NT--------GP---------SPKSMS---SFSPWIFTVGAASHDRDYSNSIVLGNNVSIPGVGLALRTDEGKKYTMISALDALKNKSSVVDKDMYVGECQDYGSFDKDVIRGNLLICSYSIRFVLGLSTIKQALAVAKNLSAKGVVFY------MDPYVLGFQINPT-P-M--D-M----PG---------------------I---II---PS--A------------------------------E-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------KV-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LKYYNSSLVRDGTTKEIVRFGAVAAIAGGQNANFSN---RAP------KI-MYY-----S--A--------R-G---P--------------------DPQDSLFNDADIL---K--------------------P------------N-----L------V-----------------A-----P-------------G-----------------NS--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------SAATEST--E----FEGE--------SF-AM----------------MSG------TSMAAPHVA----G---------------------------V------------------AA-L----VK----Q-------KFRKFS-----------------------------------------------------------------PSA--------------I---------------------ASAL-------STT-------------------------SV------------------------------------------------------------------------LFDNKGEAIMAQRAYANPDQTISPATPFDMGNGFV 696
 697 ------W----LRDG-------------------------------------GSE-YAGE--------------------------G-V--VI--------------G--------------------FID---------------------------T--------------GIDP-T------H-------------P---------S--------------------------------F---------------------S----------------DKI-SGHTYSVP---PHFTGVCEVTIGFPPGSCNRKLIGARHFA----------ESA----------------------------------------------------------------------------------------------------------------------------------------------LSRGVLNSSQDDAS------------PF-----------------------------------------------------------------------------------------D---G---------------------E--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASVAA----GNH-G-------------------------------IP------------VVVAGHRLGNAS-------------GM--APR-A--HIAIY---KA---LYKR----------F-GG--F------------AAD-------------------------------------I--------IAA--------------I-----------DQ---AA----------------QD---------------G----------V----DI-----------------------------------------INLSITPNRR--PP-GI-ATFF---------------------N--------------------------PIDM-----ALLS-A--------VKA----GI-----F--------------------------------------------------------------------------------------V---------------VQAAG-NT--------GP---------APKSMS---SFSPWIFTVGATSHDRVYSNSIILGNNVTIPGVGLASGT----------------------------------------RIMHKLVLATHA----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NSSLLRENGSGKIVGSASVAKIVGGMRPTYGI---TAP------KV-MYF-----S--A--------R-G---P--------------------DPEDDSFVDADIM---K--------------------P------------N-----L------V-----------------A-----P-------------G-----------------NA--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------PLGIGTN--D----FQGE--------RF-AM----------------ESG------TSMSAPHVT----G---------------------------I------------------AA-L----IK----Q-------KFPHFT-----------------------------------------------------------------PAA--------------I---------------------ASAL-------STT-------------------------AS------------------------------------------------------------------------LSDRKGEHIMAQRTVLNPDISQSPATPFDMGSGFV 697
 698 ------W----VQEG-------------------------------------GPQ-CAGQ--------------------------G-V--VV--------------G--------------------LID---------------------------T--------------GIDP-N------H-------------P---------S--------------------------------F---------------------A----------------DDL-TTDSYPVP---AHYAGSCEVTNDFPSGSCNRKLVGAQHFA----------ASA----------------------------------------------------------------------------------------------------------------------------------------------ITRGVFNASQDLAS------------PS-----------------------------------------------------------------------------------------D---S---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-T-----------------------ASIAA----GNN-G-------------------------------IP------------VIVAGHHFGNAS-------------GM--APR-A--HIAVY---KA---LFKG----------F-GG--F------------AAD-------------------------------------V--------VAA--------------I-----------DQ---AA----------------ED---------------N----------V----DI-----------------------------------------ISLSITPNRR--PP-GL-ATFF---------------------N--------------------------PIDM-----ALMS-A--------VKA----GI-----F--------------------------------------------------------------------------------------V---------------VQAAG-NT--------GP---------SPKSMS---SYSPWIFTVGASAHDREYKNYVVLGNNLTIPGVGLAPGTDGDSMYNLIAAPHALENNTA-SPTEVSIGECQDSSHLDKDLIRGKILICSYSIRFVLGLSSVKQALDTAKNTSAAGVIFY------LDPFVLGFQLNPT-P-M--D-V----PG---------------------L---II---PS--S------------------------------D-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------KV-------F----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSYYNESLVRDETSNGIVSFGAVAKILGGLNPNYGS---SAP------KV-MFY-----S--A--------R-G---P--------------------DPEDNTLSNADIL---K--------------------P------------N-----L------V-----------------A-----P-------------G-----------------SS--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------SLGMDSA--E----FAGE--------IF-AM----------------LSG------TSMAAPHIA----G---------------------------L------------------AA-L----IK----Q-------KYPSFS-----------------------------------------------------------------PAA--------------I---------------------GSAL-------STT-------------------------TT------------------------------------------------------------------------INDKQGNPIMSQRTYSNPDSTQTPATPFDMGNGFV 698
 699 ------W----PTGG-------------------------------------GFD-RAGE--------------------------D-V--VI--------------G--------------------FVD---------------------------S--------------GIYP-Q------H-------------P---------S--------------------------------F---------------------S----------------THK-TD-PYGPV---PHYKGKCEIDPVSRRSFCNGKIVGAQHFA----------KAA----------------------------------------------------------------------------------------------------------------------------------------------IAAGAFDPDVEFAS------------PL-----------------------------------------------------------------------------------------D---G---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------AAIAA----GNN-G-------------------------------IP------------VRMHGYEFGKAS-------------GM--APR-A--RIAVY---KV---LYRL----------F-GG--Y------------VSD-------------------------------------V--------VAA--------------I-----------DQ---AV----------------QD---------------G----------V----DI-----------------------------------------LNLSVGPNSP--PT-ATRTTFL---------------------N--------------------------PFDA-----ALLS-A--------VKA----GV-----F--------------------------------------------------------------------------------------V---------------AQAAG-NG--------GP---------FPKTLV---SFSPWITTVAAGVDDRRYKNHLILGNGKLLPGLGVSPATHGNKSFGLISATDALLGSST---TKYSALDCQRPELLNKRKVQGKILLCGYSYNYISGTASIKKVSQTARSLGAAGFVVA------VESSYPGTKFDPV-P-V--N-I----PG---------------------I---LI---TD--V------------------------------S-----------------------------R------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------KD-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDYYNSSTTRD-WAGRATVFQATVGIADGLAPTLFN---SAP------QV-ALF-----S--S--------R-G---P--------------------DVKDFSFQDADVL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------NL--------------------------------I------------------------------------------------------------------WA-AWA-----------------------------------------------------------------------------------------------PNGTDEA--N----YAGE--------GF-AM----------------MSG------TSMAAPHIA----G---------------------------I------------------AA-L----IK----Q-------KNPKWS-----------------------------------------------------------------PSV--------------I---------------------KSAL-------MTT-------------------------AN------------------------------------------------------------------------TMDKGNHPLRAQQFSTSEIMTLTRATPFDYGSGAV 699
 700 ------W----PTGG-------------------------------------GYD-RAGE--------------------------D-I--VI--------------G--------------------FID---------------------------S--------------GIFP-H------H-------------P---------S--------------------------------F---------------------A----------------SHH-TTVPYGPH---PSYKGKCEEDPHTKISFCNGKIIGAQHFA----------EAA----------------------------------------------------------------------------------------------------------------------------------------------KAAGAFNPDIDFAS------------PM-----------------------------------------------------------------------------------------D---G---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------AAIAA----GNN-G-------------------------------IP------------VRMHGYEFGKAS-------------GM--APR-A--RIAVY---KA---LYRL----------F-GG--F------------VAD-------------------------------------V--------VAA--------------I-----------DQ---AV----------------HD---------------G----------V----DI-----------------------------------------LSLSVGPNSP--PA-TTKTTFL---------------------N--------------------------PFDA-----TLLG-A--------VKA----GV-----F--------------------------------------------------------------------------------------V---------------AQAAG-NG--------GP---------FPKTLV---SYSPWITTVAAAIDDRRYKNHLTLGNGKMLAGIGLSPSTRPHRSYKMVSANDVLLGSSG---MKYNPSDCQKPEVLNKKLVEGNILLCGYSFNFVAGSASIKKVAETAKHLGAAGFVLV------VENVSPGTKFDPV-P-S--C-I----PG---------------------I---LI---TD--V------------------------------S-----------------------------K------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S-------------------------------------------------------------------------------------MD-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDYYNVTTSRD-WMGRVKDFKAEGSIGDGLEPILHK---SAP------EV-ALF-----S--A--------R-G---P--------------------NTKDFSFQDADLL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------SL--------------------------------I------------------------------------------------------------------WS-AWS-----------------------------------------------------------------------------------------------ANGTDEA--N----YIGE--------GF-AL----------------ISG------TSMAAPHIA----G---------------------------I------------------AA-L----VK----Q-------KHPQWS-----------------------------------------------------------------PAA--------------I---------------------KSAL-------MTT-------------------------ST------------------------------------------------------------------------VIDRAGRPLQAQQYSETETVTLVKATPFDYGSGHV 700
 701 ------W--QKISNE-------------------------------------GDR-RAGE--------------------------D-I--VI--------------G--------------------FVD---------------------------T--------------GINP-T------H-------------P---------S--------------------------------F---------------------A----------------ALD-LTNPYSSNLSRLHFSGDCEIGPFFPPGSCNGKIISARFFS----------AGA----------------------------------------------------------------------------------------------------------------------------------------------RASGALNSSLDILS------------PF-----------------------------------------------------------------------------------------D---A---------------------S--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-V-----------------------ASIAA----GNA-G-------------------------------VP------------VIVDGFFYGRAS-------------GM--APR-S--RIAVY---KA---IYPS----------I--G--T------------LVD-------------------------------------V--------IAA--------------I-----------DQ---AI----------------MD---------------G----------V----DV-----------------------------------------LTLSVGPDEP--PV-DK-PTVL---------------------G--------------------------IFDL-----AMLL-A--------RKA----GV-----F--------------------------------------------------------------------------------------V---------------VQAVG-NN--------GP---------SPSSVL---SYSPWVVGVAAGNTDRSYPAPLILDGGQTVQGVGLSGPT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EEKTFRD-TRGVATQFGARARIGEGRNSVFAG---KAP------VV-SRF-----S--S--------R-G---P--------------------AFIDATRSPLDVL---K--------------------P------------D-----I------L-----------------A-----P-------------G-----------------HQ--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------LPSAFDP--I----LTGR--------SF-AI----------------LSG------TSMATPHIA----G---------------------------I------------------GA-L----IK----Q-------LNPSWT-----------------------------------------------------------------PAM--------------I---------------------ASAI-------STT-------------------------AN------------------------------------------------------------------------EYDSNGEIISAEYYELS---RLFPSNHFDHGAGHV 701
 702 ------W----PLLG-------------------------------------GAE-NSGD--------------------------G-I--VI--------------G--------------------MID---------------------------T--------------GIDP-K------N-------------P---------S--------------------------------F---------------------A----------------GF--SDQAKPPP---ASFKGMCRSGDRFPPDSCNGKIVGARWFA----------RAG----------------------------------------------------------------------------------------------------------------------------------------------QATGEFNATIHYAS------------PY-----------------------------------------------------------------------------------------D---P---------------------D--------------------------------------------------------------------------------------------------------------------------------------------------GHG-------SH-T-----------------------ASTAA----GNF-H-------------------------------AP------------AISRGYNFGYAS-------------GM--APG-A--RLAIY---KA---AYP-----------F-GG--Y------------MSD-------------------------------------V--------IAA--------------V-----------DQ---AV----------------ED---------------G----------V----DV-----------------------------------------ISLSMAPSSV--SS-GP-ASFL---------------------N--------------------------LLET-----QLLL-A--------TKA----GV-----S--------------------------------------------------------------------------------------V---------------VQAVG-NG--------GP---------DASSIV---SFSPWITSVAASTTDRKYNKSIITGHGQVFSCGAISPSTPGETMYPLALADDVSIANST-----DGSNSCQDPKVFIRSLVQGKVIICMIVSSNYYEGDSLTNIIDTAQKIGAVGVVIADRYSGDVD-----IEYQPTFP-T--A-I----PS---------------------A---IV---VN--G------------------------------V-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------MN-------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LEYYDNNTARG-DDGGVMAFGASVRILEGRRASYSG---EPP------MV-ADY-----S--S--------R-G---P--------------------NVENAQMQAADVL---K--------------------P------------N-----V------M-----------------A-----P-------------G-----------------HH--------------------------------I------------------------------------------------------------------WG-AWS-----------------------------------------------------------------------------------------------PTSDAMP--E----IQGE--------SY-AI----------------LSG------TSMSTPHVA----G---------------------------V------------------AA-L----IR----Q-------RHPTWS-----------------------------------------------------------------PAM--------------V---------------------MSAI-------MTT-------------------------AE------------------------------------------------------------------------ATDRSGRPLMARRDVG----AVVAATPFDMGAGAI 702
 703 -----------------------------------YGYSNTGLRQINVDKLHEMG-YDGF--------------------------G-I--KI--------------L--------------------ITD---------------------------T--------------GYRK-S------H-------------E---------V--------------------------------FKHMKIIGEYNFL-KNK---NNTQDD----FDPFF-KDVNEQQT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-T-----------------------LSTLGGYRPGVL-----------------------------------------------------------------------IGA--AYN-A--SFLLA---E--------------------------TENAT-SDFPLEEDNW--------------------------------------------IAA--------------I-----------EW--------------------------------------G----------ESHGAQL-----------------------------------------VSSSLGYE---NWY-TY-A-NK-------------DGHFSKISR-----------------------------------VATM---------AVNK----GM-----V--------------------------------------------------------------------------------------V---------------VMGVG-NSG----D--LGMGI----------------------------------------------------------------------------------------------------------------------------------------------------------PADAEY-----------------------------V---IS---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDSNGERTEF--------S--------SIGPT-------------------------------------------------------------------------------------------------------ADGRIKP-------------E---------------------------------------------------V------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGLGNLVAHNLNDTTYDRFDG------TSFSCPLVA----S---------------------------G------------------IALL----MQ------------AHPNWS----------------------------------------------------------------------------------P------------------KQIYEAV-------ISS-------------------------------------------------------------------------------------------------------ASKSKSPDYLMGFGIFN-------------- 703
 704 -----------------------------------YGNTFNQVSQVGIDKLQSLG-YDGY--------------------------G-V--TI--------------L--------------------MLD---------------------------S--------------GFYK-S------H-------------E---------A--------------------------------FDHLNIIAEHNFI-DGS---NNTQGE------------MDDTQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TA-T-----------------------LSTIGAYMPGVM-----------------------------------------------------------------------VGA--AYN-A--SFILG---K--------------------------TEIVS-VESIIEEDYW--------------------------------------------IAG--------------I-----------EW--------------------------------------G----------EGLGAQL-----------------------------------------VSSSLGYT---QWY-NY-Y-DL-------------NASVAHITM-----------------------------------MADF---------ATTK----GM-----V--------------------------------------------------------------------------------------V---------------VVSAG-NSG----N--NGIGA----------------------------------------------------------------------------------------------------------------------------------------------------------PADGKH-----------------------------V---IS---VG--A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMNETGINTSF--------S--------SIGPS-------------------------------------------------------------------------------------------------------ADGRVKP-------------D---------------------------------------------------I------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGYKNFVASYHGRVNYTLMSG------TSFACPLAA----S---------------------------G------------------IALL----IQ------------ARPNWS----------------------------------------------------------------------------------N------------------KQIYEAV-------LGS-------------------------------------------------------------------------------------------------------GSNAFSPNSKIGFGTFN-------------- 704
 705 ------------------------------------------IKQVGIDQLQAEGDYNGD--------------------------G-I--RI--------------L--------------------ILD---------------------------S--------------GFNK-S------H-------------E---------V--------------------------------FQNMKIAGEYNFV-DNI---ADTGNT----YDPVY-----DDPL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TA-T-----------------------LSVLGGYKPGVL-----------------------------------------------------------------------VGA--AYR-A--SYLLA---K--------------------------TEDVR-SESPIEEDNF--------------------------------------------IAA--------------I-----------EW--------------------------------------G----------EQLGADL-----------------------------------------LSASLGYL---SWV-DY-F-DM-------------DGKTNRITK-----------------------------------VADI---------AVTK----GM-----V--------------------------------------------------------------------------------------C---------------IISAG-NEG----E--TGISE----------------------------------------------------------------------------------------------------------------------------------------------------------PADDSD-----------------------------V---IS---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDIKGDRTFF--------S--------SVGPS-------------------------------------------------------------------------------------------------------ADGRVKP-------------D---------------------------------------------------V------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGKNVAAAFVHSQNNYMTLDG------TSFSCPLVA----G---------------------------I------------------AALL----MQ------------AHPNWS----------------------------------------------------------------------------------A------------------NQIKQAL-------LKT-------------------------------------------------------------------------------------------------------SSKSSNPDQYMGHGIVDAYKA---------- 705
 706 -----------------------------------YGKTYLGINQLNINKIQELG-YNGS--------------------------G-I--II--------------L--------------------ILD---------------------------S--------------GFYK-S------H-------------Q---------V--------------------------------FQHLNIIDEYNFV-DNI---VDTSNN----YQGYE------SST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TA-T-----------------------LSLLAAYNPGVM-----------------------------------------------------------------------VGA--AYG-S--SVLLG---K--------------------------TEDVR-SETQVEEDDW--------------------------------------------IAA--------------I-----------EW--------------------------------------G----------ERLGATL-----------------------------------------VSSSLGYT---DWY-KF-Y-QM-------------DGT-TRLAK-----------------------------------IADI---------ATEK----GM-----L--------------------------------------------------------------------------------------I---------------VNSAG-NDG----A--KGIGS----------------------------------------------------------------------------------------------------------------------------------------------------------PADGKY-----------------------------V---IS---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDQNGNVAPF--------S--------SIGPS-------------------------------------------------------------------------------------------------------SDGRVKP-------------D---------------------------------------------------V------------------------------------------------------------------MG--------------------------------------------------------------------------------------------------------------------------------LGVKNYYASPTGYSSYAIGSG------TSFSCPLVA----S---------------------------G------------------IALL----MQ------------AHPNWS----------------------------------------------------------------------------------P------------------IQIQEAL-------LKT-------------------------------------------------------------------------------------------------------SSNYLNPNIYYGYGIFN-------------- 706
 707 ----------------------------------------------------KLG-FDGT--------------------------G-V--II--------------L--------------------ITD---------------------------T--------------GFYK-Q------H-------------E---------V--------------------------------FKNLNILGEYNFI-EKN---NRIEDE----FNGTS-ESVEFSQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TA-T-----------------------LSVLAGFKKGHL-----------------------------------------------------------------------VGT--AYN-A--SFLLA---R--------------------------TESLDMED-VIEEDYF--------------------------------------------ASA--------------I-----------EW--------------------------------------G----------ESRGAHL-----------------------------------------VSCSLGYQ---DWY-NV-ASDL-------------NGKISHMTK-----------------------------------IADL---------ASKK----GM-----V--------------------------------------------------------------------------------------V---------------VSGIG-NSG----E--DGLGA----------------------------------------------------------------------------------------------------------------------------------------------------------PADGNY-----------------------------V---IA---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDAKGKRVDF--------S--------SVGPS-------------------------------------------------------------------------------------------------------SDSRIKP-------------E---------------------------------------------------V------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGNEVYLAGIMNTTNYVYYNG------TSFSCPIVA----G---------------------------G------------------IALL----IQ------------AHPNWT----------------------------------------------------------------------------------P------------------YQIYDAV-------VRS-------------------------------------------------------------------------------------------------------ASNSSHPDVYNGFGLFDAYASY--------- 707
 708 -----------------------------------YGKSADGIKQISMDKLIEMG-LDGS--------------------------G-V--VI--------------L--------------------IID---------------------------D--------------GFYK-D------H-------------Q---------C--------------------------------FKKLRILGELNLD-QQSPHMNDTQDR-----------PMMEEDH----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TA-T-----------------------LSVLSCDMPGVM-----------------------------------------------------------------------IGG--ARN-A--SYLLA---R--------------------------ITIFDEIDSYIEEDQW--------------------------------------------VVA--------------L-----------EW--------------------------------------G----------EKMGADL-----------------------------------------VSSSLSYL---LSF-NYSFAGL-------------DGKTSHTTI-----------------------------------ATNL---------ASSK----GV-----L--------------------------------------------------------------------------------------I---------------VNSMG-NND----F--SIYGA----------------------------------------------------------------------------------------------------------------------------------------------------------PNDGEN-----------------------------V---IS---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDRRGNMAYF--------S--------SIGPT-------------------------------------------------------------------------------------------------------ADGRIKP-------------D---------------------------------------------------T------------------------------------------------------------------LA--------------------------------------------------------------------------------------------------------------------------------LGIDIYVASISGPSNFTRMSG------TSFSCPLVA----S---------------------------A------------------IALL----MQ------------AKPNWT----------------------------------------------------------------------------------S------------------TQLHEAV-------IDS-------------------------------------------------------------------------------------------------------CEWSIYPHYYMGWGIFN-------------- 708
 709 -----------------------------------YGESFQGISQTSIDKLQRLG-YDGY--------------------------G-L--KI--------------I--------------------VMD---------------------------T--------------GFYK-D------H-------------D---------A--------------------------------FKHLKIIGEHNFI-DNT---NDTQEDPVENEDPRY------SQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TA-T-----------------------LSVLGGFIPGKL-----------------------------------------------------------------------VGA--AYN-A--SYLLA---K--------------------------TEIVEGEDTVIEEDNW--------------------------------------------IAA--------------L-----------EW--------------------------------------G----------EKLGASI-----------------------------------------ISSSLSYQ----LY-NY-P-EM-------------NGKDSHLTK-----------------------------------AANL---------AIYK----GM-----I--------------------------------------------------------------------------------------V---------------VNSMG-NKD----Y--SIFGA----------------------------------------------------------------------------------------------------------------------------------------------------------PADGEN-----------------------------V---IS---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDSSGRYAPF--------S--------SIGPT-------------------------------------------------------------------------------------------------------ADGRIKP-------------D---------------------------------------------------I------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGVGYYIALSTSRSSFSSVDG------TSFACPLVA----S---------------------------G------------------IALL----MQ------------AHPDWN----------------------------------------------------------------------------------T------------------QQIYQAV-------LST-------------------------------------------------------------------------------------------------------GSKASNPDPYVGFGVFN-------------- 709
 710 ------------------------------------------------DKLHQEG-YYGT--------------------------N-I--KI--------------L--------------------IID---------------------------S--------------GFYK-D------H-------------E---------S--------------------------------LKHINYIGEYNYV-DKK---NDTQDE----FDPNL-TDPTMSQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TA-T-----------------------LSVIGGFAPGKL-----------------------------------------------------------------------IGS--AFN-A--SYFLA---K--------------------------TEIIF-EENLVEEDYW--------------------------------------------IAA--------------L-----------EM--------------------------------------G----------ERMGIDL-----------------------------------------VTSSLGYK---EWY-RF-S-DL-------------NGKTTRISK-----------------------------------AANL---------AIKK----GL-----V--------------------------------------------------------------------------------------I---------------VISTG-NDD----K--KGIDS----------------------------------------------------------------------------------------------------------------------------------------------------------PTDSEY-----------------------------V---IA---VG--G-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTPSGHEKSF-----I--S--------SMGPS-------------------------------------------------------------------------------------------------------SDGRIKP-------------D---------------------------------------------------I------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGEQVQIAYFTGKDHYRLEIG------TSFSSQIVA----G---------------------------G------------------IALI----ME------------KNKDWN----------------------------------------------------------------------------------A------------------YQIYEAI-------TKT-------------------------------------------------------------------------------------------------------ASKANNPDINMGYGIFNAYAA---------- 710
 711 --------------------------------------------------LHKLG-FDGY--------------------------G-V--KI--------------L--------------------VMD---------------------------S--------------GFWK-D------H-------------A---------V--------------------------------FQKMKIMGEHNFI-NNS---TNTTNP----FNPNN-QEAMNSDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TA-V-----------------------LSVIGGYLPGEL-----------------------------------------------------------------------IGP--AYN-A--SFYLA---KI-----------------------LDNEEIWNTDGIGSEDAY--------------------------------------------IGA--------------L-----------EY--------------------------------------A----------ERNGIDI-----------------------------------------VTTSVG-----GYY-GN-YYET-------------NYVESPISI-----------------------------------ASTI---------MVSK----GV-----I--------------------------------------------------------------------------------------F---------------VNSAG-NNG----EFNMGVAE----------------------------------------------------------------------------------------------------------------------------------------------------------PSNLKD-----------------------------V---IS---VG--S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDFDNNRSYF--------S--------SSGPN-------------------------------------------------------------------------------------------------------VQGIIKP-------------D---------------------------------------------------V------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------GGSQIYCADLID-NSFTFYYG------TSFSAPITA----G---------------------------A------------------IALL----LQ------------AHPNWK----------------------------------------------------------------------------------V------------------YQIHEAL-------LST-------------------------------------------------------------------------------------------------------ASLSSSPNKKMGFGVVDAFAAF--------- 711
 712 --------------------------------------------------LHQMG-LDGS--------------------------G-V--KI--------------L--------------------IID---------------------------S--------------GYHK-D------H-------------P---------S--------------------------------LQHLKVVKEFGFY-NLS-------------------DISADDKN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TA-T-----------------------LSVIGGYLPGSH-----------------------------------------------------------------------IGP--AYN-A--SYYLS---K------------------------MD-----LTEGLAFFDSI--------------------------------------------PEG--------------I-----------EV--------------------------------------A----------EREGIDL-----------------------------------------ITCSMGFGQIDGEY-LY-YNED-------------EYFIT--KI-----------------------------------ADT----------LVSK----GV-----V--------------------------------------------------------------------------------------F---------------VSSAG-NTG----E--TGMYS----------------------------------------------------------------------------------------------------------------------------------------------------------PAYSEH-----------------------------V---IT---VG--S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VSLDGSATEW--------S--------SNGPN-------------------------------------------------------------------------------------------------------ANGIVKP-------------D---------------------------------------------------I------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------LGVNI--SIVWN-NTFALAMG------TSFSAPLVA----G---------------------------G------------------IALL----LQ------------AHPTWT----------------------------------------------------------------------------------P------------------QQIHEAI-------LST-------------------------------------------------------------------------------------------------------GSMVNSPNSIHGYGVFDAYKAL--------- 712
 713 -----------------------------------YGQSYTQLNQLQVPAVHDLG-FDGS--------------------------G-V--TI--------------C--------------------VMD---------------------------A--------------GFNNLA------H-------------V---------A--------------------------------FDSMNIIAMWDFV-NGD---PNVGDE------------GDMGTG----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TN-T-----------------------LSVIGGYAPGNL-----------------------------------------------------------------------IGP--AYR-S--NYILA---K--------------------------TENTD-SETPVEEDNW--------------------------------------------VAA--------------I-----------EW--------------------------------------A----------DSIGVDV-----------------------------------------TSTSLGYLEYDPPFTSYTWQDM-------------NGNTAVITI-----------------------------------AADL---------AVKK----GI-----V--------------------------------------------------------------------------------------V---------------VNSAG-NEGWR--STPNSLVA----------------------------------------------------------------------------------------------------------------------------------------------------------PADGDS-----------------------------V---FA---IG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDASGTRVSF--------S--------SFGPT-------------------------------------------------------------------------------------------------------FDGRIKP-------------D---------------------------------------------------F------------------------------------------------------------------MA--------------------------------------------------------------------------------------------------------------------------------MGSNVYAARSSGTTQYTYVSG------TSFSCPLSA----G---------------------------V------------------VALL----LQ------------ANPNLT----------------------------------------------------------------------------------P------------------IQLRTIL-------RQT-------------------------------------------------------------------------------------------------------SSRSNTPDNFYGWGII--------------- 713
 714 ---------------------------------------------------HKLG-YKGK--------------------------G-V--TI--------------M--------------------IAD---------------------------T--------------GFMK-S------H-------------E---------A--------------------------------LKNIKIKKERDFI-END---DNTEGS-------------DLAQE----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------LSQIGSNIPGKI-----------------------------------------------------------------------MGA--APE-A--EFLLA---K--------------------------TEIVA-TETSVEEDYL--------------------------------------------IKA--------------I-----------EW--------------------------------------G----------ESEGADV-----------------------------------------VSISLSYS---SYY-EY-W-ER-------------DGS-SPLSK-----------------------------------AIDI---------ASTK----GI-----V--------------------------------------------------------------------------------------V---------------VIASG-NDG----E--KGIGP----------------------------------------------------------------------------------------------------------------------------------------------------------PGDSNL-----------------------------A---VT---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDNFGDVAIF--------S--------SAGPT-------------------------------------------------------------------------------------------------------SDGRLKP-------------E---------------------------------------------------V------------------------------------------------------------------VA--------------------------------------------------------------------------------------------------------------------------------RGVLCYGASDQSVDTYKYQSG------TSHSAPLVA----G---------------------------S------------------VALL----LE------------AHPTWN----------------------------------------------------------------------------------P------------------KQIKEAL-------IKT-------------------------------------------------------------------------------------------------------SSQFKAPDNYKGFGIINIVDA---------- 714
 715 -----------------------------------YGKSYSQLNQIGVLEAHKLG-YKGN--------------------------G-T--TI--------------M--------------------VID---------------------------T--------------GFLK-S------H-------------E---------S--------------------------------LGGLRIRGERDFI-EHT---DNTESG-------------GLKQI----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------LSQIGGNKPGKI-----------------------------------------------------------------------IGV--APD-A--DFILA---K--------------------------TEIVS-EEIPIEEDYL--------------------------------------------IES--------------I-----------EW--------------------------------------G----------ESMGADV-----------------------------------------ISISLSYT---QNY-EY-W-QR-------------DGT-SPLSK-----------------------------------AIDI---------ATDK----GV-----V--------------------------------------------------------------------------------------V---------------VVASG-NDG----E--VGVGP----------------------------------------------------------------------------------------------------------------------------------------------------------PGDSKF-----------------------------A---IT---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDAFGEIATF--------S--------SYGPT-------------------------------------------------------------------------------------------------------SDGRLKP-------------E---------------------------------------------------V------------------------------------------------------------------SA--------------------------------------------------------------------------------------------------------------------------------KGVLCFGADDSEIDSYRYTSG------TSHATPLIA----G---------------------------S------------------VALI----IE------------AHPNWT----------------------------------------------------------------------------------P------------------KQIKEVL-------LKT-------------------------------------------------------------------------------------------------------ASQSQSPDNFKGFGIIN-------------- 715
 716 --------------------------------------------------LHKKG-YHGE--------------------------N-I--TI--------------L--------------------VID---------------------------D--------------DFYL-K------H-------------P---------A--------------------------------FKTMTVIDQKEFF-NSN---NQTKTNEDLRSKGLK----ENGEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TS-V-----------------------LSVIGGFEVGKI-----------------------------------------------------------------------VGP--AYK-S--KYLLG---K--------------------------IKVSEEEDSTFEEDQF--------------------------------------------IAA--------------L-----------EW--------------------------------------G----------ENKGAQV-----------------------------------------ISSSLSFC---LSL-DYSYFNL-------------DGKQSLTTK-----------------------------------AANI---------AIEK----GI-----V--------------------------------------------------------------------------------------F---------------VNAMG-NDD----F--SIFGG----------------------------------------------------------------------------------------------------------------------------------------------------------PNDGEY-----------------------------V---IA---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDEYGGIASF--------S--------SVGPT-------------------------------------------------------------------------------------------------------ADGRYKP-------------E---------------------------------------------------T------------------------------------------------------------------QA--------------------------------------------------------------------------------------------------------------------------------MGINVNVADVLSNTKYSEFSG------TSFSTPLIA----G---------------------------A------------------VALL----IQ------------AHPTWT----------------------------------------------------------------------------------P------------------KQIHQAI-------IGG-------------------------------------------------------------------------------------------------------SIWSSSPHYLLGYGLLDSEKAL--------- 716
 717 -----------------------------------YGASFTQLNLSDIPFVHSKG-IDGR--------------------------N-V--LV--------------G--------------------LLD---------------------------S--------------GFDWKR------H-------------T---------S--------------------------------LSTRNVIAEYDFVFDDSVTANQSQDV--------------PGQD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TL-V-----------------------FSIIGGYRNSVL-----------------------------------------------------------------------IGS--AFN-S--SFLLA---K--------------------------TEYIA-TETHTEEDNY--------------------------------------------AAA--------------L-----------IW--------------------------------------M----------ENLGVDI-----------------------------------------TSSSLGYSEFDTGEDSYTYEDM-------------NGKTTIVSK-----------------------------------AIDL---------AFER----GV-----V--------------------------------------------------------------------------------------T---------------FTSAG-NEGNT--KW-KYITA----------------------------------------------------------------------------------------------------------------------------------------------------------PADAFN-----------------------------V---IA---VG--S-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDSQNRLASF--------S--------SVGPT-------------------------------------------------------------------------------------------------------YDGRIKP-------------E---------------------------------------------------I------------------------------------------------------------------VA--------------------------------------------------------------------------------------------------------------------------------MGVSVYGALAGTTDEYRFANG------TSTSSPIAA----G---------------------------V------------------AALL----LS------------KFPHLT----------------------------------------------------------------------------------N------------------SQVRSII-------LES-------------------------------------------------------------------------------------------------------SSNSQSPNNQIGYGLISAKSALEFPNIRQVN 717
 718 ----------------------------DPQRSDSLYGPAITQIEMSRANLLHDAGFKGQ--------------------------G-M--TI--------------A--------------------VID---------------------------A--------------GFHNADRIEAMKNIRILGTRDFVNPEA---------D--------------------------------IYAES-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------MS-V-----------------------LSCMA-----------------------------------------------------------------------MNQPNVMVGT--APE-A--SYWLL---RSEDEASEH---------------------------------------------------------------------L--------VEQDYWAAAIEFADSVGV-------------------------------------------------------------------DV-----------------------------------------VNTSLGYYTFDDPT--------------------------------------------KNYRYRDLNGHYALMSREASKAADK-----------------GM-----V--------------------------------------------------------------------------------------L---------------VCSAG-NSGSGSWKKITP-------------------------------------------------------------------------------------------------------------------------------------------------------------PGDAEN-----------------------------V---LT---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDKKKLLAPF-----S-----------SVGNT-------------------------------------------------------------------------------------------------------ADGRVKP-------------D---------------------------------------------------V----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VAVGLKADIVGTDGNLRLANG------TSFSSPIMC----G---------------------------M------------------VACL----WQ------------ACPRLT----------------------------------------------------------------------------------A------------------KEVIELV--------------------------------------------------------------------------------------------------------------RSVGDRSDFPDNIYGYGIPDLWKAYQ-------- 718
 719 -----------------------PI---SFYANNIGAYGGTIGEDINVKKAWE-KGISGN--------------------------N-V--TL--------------V--------------------IAD---------------------------D--------------GC-------------------------------------------------------------------YTTHYDFMDRFN---NNLNLAFSAPF-DDINPQVETDS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TA-C-----------------------LGMAA----ASSNN------------------------------------------------------------------YCSIGV--APN-S--TIGCH---RFGA--NDAS-IGNIVKSLTTSLND-----------------------------------------------------I---------------------------------------------------------------------------------------------DV-----------------------------------------ISFSWGV-ECDPS---SSA------------------------------------------------------------RCYFYQSHPVVDEALDKSVTQGRNGKGRI--------------------------------------------------------------------------------------I---------------VFAAG-NEQENGQNSNEYLLNK--DRRV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IS---VS--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--T--------YKGSAAYYTAPGSNILVNTPSG-GDSSFM------------------------------------------------------AGSD-------------------------YTP-------------T---------------------------------------------------L------------------------------------------------------------------FT--------------------------------------------------------------------------------------------------------------------------------------SSIFGDSSCTNTFTG------SSASCPQVA----G---------------------------C------------------CALM----LQVN------------KELT----------------------------------------------------------------------------------W------------------RDVQMIL-------ALTSTINDPESIYWKKNGAGYLYSHYSGF------------------------------------------------------------------------------------------------------------ 719
 720 -----------------------PV---QYYIENTGQQTGIPNEDLNITSVWK-QNIYGN--------------------------N-I--KI--------------T--------------------VTD---------------------------N--------------GCIP-S------D-------------P---------S--------------------------------ISKKYDEANSWNFAESCLTLAVSDPYCKEVQPNYSDEYF---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FHG-------TS-C-----------------------AHLAG----GSMDS------------------------------------------------------------------RCGPGI--APK-S--SISCM---KLDEYLNTHN-MKALI-SMLSKIRN-----------------------------------------------------V---------------------------------------------------------------------------------------------DV-----------------------------------------NTNSWGP-ACDLNKDLQTA------------------------------------------------------------FCPQSRRLEVYQKALEHTIETGRNGLGTI--------------------------------------------------------------------------------------I---------------LFAAG-NEGHLGDDTSFKILNC--ERYV------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IG---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--T--------NEGTRAFYSSRGNSILVNAPSG-GRDFYS------------------------------------------------------YSEE-------------------------HLP-------------G---------------------------------------------------I------------------------------------------------------------------YT--------------------------------------------------------------------------------------------------------------------------------------TTGF---KCMSNFSG------TSAAAPQVA----G---------------------------I------------------VALM----LEAN------------PKLS----------------------------------------------------------------------------------W------------------RDVQAVL-------AITSTINDPTCPSWTKNKAGYYHSPYHGF------------------------------------------------------------------------------------------------------------ 720
 721 ---------------------------PQQWHLKQTTINGKV-INAHANVEAAWKLSDGT--------------------------GAI---I--------------A--------------------IID---------------------------D--------------GVDL-D------H-------------E---------E--------------------------------F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSSGKIVAPRDVT--RKNDNPRP---GNDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TA-C-----------------------AGVACG--NGKFGA---------------------------------------------------------------------SGV--APG-A--KLMPI---RLASSLGSQD-EADAFIWAAQNG--A--------------------------------------------------------------------------------------------------------------------------------------------------DV-----------------------------------------ISCSWGPADGTWFEPNDPLHKQ-------------KV------------------------------------------PLPDSTRLAMDFAINKGRNGKGC-----V--------------------------------------------------------------------------------------I---------------LFAAG-NGNES--VDNDG-------------------------------------------------------------------------------------------------------------------------------------------------------------Y-ASYQKV-------------------------------IA---IA--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDFGTRSAY-----S--D--------F-GQAVW-----------------------------------------------------------------------------------CAFPSN--N------GDSS--Q-TP-------------G---------------------------------------------------I------------------------------------------------------------------WT----------------------------------------------------------------------------------------------------------------------TDRVGVLGYNSG-NVNLGD-AGGNYTNEFGG------TSSACPGAA----G---------------------------V------------------TALI----IA------------RNPNLR----------------------------------------------------------------------------------W------------------DEVRDII-------KRS----------------------------------------------------------------------------------------------CDRIDQAGGKYDANGRSPFYGYGRINALKAVELAKPAQTS 721
 722 ---------------------------PPQWHLKQTTIGGKT-INAHANVEAAWKLSDGT--------------------------GTI---I--------------A--------------------IID---------------------------D--------------GVDI-D------H-------------E---------E--------------------------------F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSSGKIVAPRDVT--RKTNFPTP---GNRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TA-C-----------------------AGVACG--NGNFGA---------------------------------------------------------------------SGV--APG-A--KLMPI---RFVSALGSQD-EADSFVWAAQNG--A--------------------------------------------------------------------------------------------------------------------------------------------------DV-----------------------------------------ISCSWGPPDGTWWDDKDPLHKQ-------------KV------------------------------------------PLPDSTRLAMDYAINKGRNGKGC-----V--------------------------------------------------------------------------------------I---------------LFAAG-NGNES--VDNDG-------------------------------------------------------------------------------------------------------------------------------------------------------------Y-ASYEKV-------------------------------IA---VA--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDFGTRSAY-----S--D--------F-GTAVW-----------------------------------------------------------------------------------CAFPSN--N------GNPS--Q-TP-------------G---------------------------------------------------I------------------------------------------------------------------WT----------------------------------------------------------------------------------------------------------------------ADRTGVVGYNSG-NTNLGD-QAGNYTNSFGG------TSSACPGAA----G---------------------------V------------------AALI----LS------------RNPNLR----------------------------------------------------------------------------------W------------------DEVRDII-------KRS----------------------------------------------------------------------------------------------CDRIDPVGGNYNAEGRSPFYGYGRINALKAVELALPAQPE 722
 723 ----------------------------NQWHLKKTTVRHEVEVDASANVENAHKITLGK--------------------------GTI---I--------------A--------------------VID---------------------------D--------------GFDM-G------H-------------P---------E--------------------------------F-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRKGKIVHPCNLSGVNTDDDPTP---GKYD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TP-C-----------------------AGVACA--DGRYGA---------------------------------------------------------------------SGV--APE-A--NLMPI---RQAGGLGSLD-EALAFVWATDNG--A--------------------------------------------------------------------------------------------------------------------------------------------------DV-----------------------------------------ISCSWGPKGSLSANSDDPQHDV-------------VA------------------------------------------ALPALTRMAIDYAIDKGRKGKGC-----V--------------------------------------------------------------------------------------V---------------LLAAG-NGNES--VEKDG-------------------------------------------------------------------------------------------------------------------------------------------------------------Y-ASYEPV-------------------------------IA---VA--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CNDRSIRSVY-----S--N--------Y-GKSLW-----------------------------------------------------------------------------------CSFPSD--DSEDLILGHPA--PLTT-------------G---------------------------------------------------I------------------------------------------------------------------WT----------------------------------------------------------------------------------------------------------------------TDLRREYGDNPGASTAVGD-IFGNYINNFGG------TSSACPGAA----G---------------------------V------------------AALI----IS------------VNPTLN----------------------------------------------------------------------------------Y------------------QEVKDII-------RDS----------------------------------------------------------------------------------------------CDKIDEKNGGYDENGHSEWYGYGRVNAGKAVSLAQKLYQE 723
 724 ----------------------------------------------------------GS--------------------------EEV--VI--------------G--------------------ISD---------------------------D--------------GCKV-D------H-------------P---------D--------------------------------FNSTNKFVGYGYFKNERLFVNSDSDFQREQMYMTCK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TS-C-----------------------AGVIAAEVDAQFTV----------------------------------------------------------------------GA--APG-C--SLLPI---KW------------------------------------ESK----------------------------------------------EEG--------------LFISDSKLMTVLNY-------------------------------------------------IADKVDV-----------------------------------------FSNSWG---------------------------------------------------------------RSPERTWPIQVLEKITELTKTGGRRHK----GI-----V--------------------------------------------------------------------------------------F---------------LWAAG-NENC---------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEHNALVDVPYTDGWKDGSWVGVMKAKNFHHSLVSIPGVMF--VGALS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIAQRSHYSNYGF-GLSIS-----------------------------------------------------------------------------------------------------A-----PSSNLHEYFRMTVTG-----------------VP--------------------------------I------------------------------------------------------------------TTAT------------------------------------------------------------------------------------------------------------------------------GSIPVLHGACIPENVTSRFGG------TSSATPLVA----G---------------------------I------------------AALT----IS------------ANPQLS----------------------------------------------------------------------------------A------------------LDIISIL-------KSTASKNL--------------------------------------------------------------------------------------------------------------------------------- 724
 725 ----------------------------------------------------------GS--------------------------EEV--VI--------------G--------------------ISD---------------------------D--------------GCKI-D------H-------------P---------D--------------------------------FNSINKFAGYGYFKNERLFVNSDSDFQREQMYMACK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TS-C-----------------------AGVIAAEVDGQFTV----------------------------------------------------------------------GA--APG-C--SLLPI---KW------------------------------------ESK----------------------------------------------EEG--------------LFISDSKLMTVLNY-------------------------------------------------IADKIDV-----------------------------------------FSNSWG---------------------------------------------------------------RSPERTWPIQVLEKITELTKTGGRRRK----GI-----V--------------------------------------------------------------------------------------F---------------LWAAG-NENC---------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEHNALVDVPYTDGWKDGSWVGVMKAKNFHHSLASIPGVMF--VGALS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SIAQRSHYSNYGF-GLSIS-----------------------------------------------------------------------------------------------------A-----PSSNLHEYFRMPVTG-----------------IP--------------------------------I------------------------------------------------------------------TTAT------------------------------------------------------------------------------------------------------------------------------GSIPVLHGACIPENVTSRFGG------TSSATPLVA----G---------------------------I------------------AALT----IS------------ANPQLS----------------------------------------------------------------------------------A------------------LNIISIL-------KSTASKN---------------------------------------------------------------------------------------------------------------------------------- 725
 726 ----------------------------------------------------------GS--------------------------EEV--VI--------------G--------------------FSD---------------------------D--------------GCKV-D------H-------------P---------D--------------------------------FNSTNKFASYGYFKNERLFVNTDSDFQKQQMYITCK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TS-C-----------------------AGVIAAEVDAQFTV----------------------------------------------------------------------GA--APG-C--RLLPI---KW------------------------------------ESN----------------------------------------------EEG--------------LFITDSKLITVLNY-------------------------------------------------IADKVDV-----------------------------------------FSNSWG---------------------------------------------------------------RSPERTWPIQVLEKITELTKTGGRRRK----GI-----V--------------------------------------------------------------------------------------F---------------LWAAG-NENC---------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEHNALVDVPYTDGWENGSWVGVIKAENFHHSLVSIPGVMF--VGALS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLAQRSHYSNYGF-GLSIT-----------------------------------------------------------------------------------------------------A-----PSSNLHEYFRMPVKG-----------------VP--------------------------------I------------------------------------------------------------------TTTT------------------------------------------------------------------------------------------------------------------------------GSIPVLHGNCIPENVTSRFGG------TSSATPLVA----G---------------------------I------------------AALT----IS------------ANPHLS----------------------------------------------------------------------------------A------------------LEVISIL-------KSTASKN---------------------------------------------------------------------------------------------------------------------------------- 726
 727 ----------------------------------------------------------GS--------------------------EEV--VI--------------G--------------------FSD---------------------------D--------------GCKV-D------H-------------P---------D--------------------------------FNSTNKFASYGYFKNERLFVNTDSDFQKQQMYITCK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TS-C-----------------------AGVIAAEVDAQFTV----------------------------------------------------------------------GA--APG-C--RLLPI---KW------------------------------------ESN----------------------------------------------EEG--------------LFITDSKLITVLNY-------------------------------------------------IADKVDV-----------------------------------------FSNSWG---------------------------------------------------------------RSPERTWPIQVLEKITELTRTGGRRRK----GI-----V--------------------------------------------------------------------------------------F---------------LWAAG-NENC---------------------------------------------------------------------------------------------------------------------------------------------------------------------PIEHNALVDVPYTDGWENGSWVGVIKTKNFHHSLVSISGVMF--VGALS----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLAQRSHYSNYGF-GLSIT-----------------------------------------------------------------------------------------------------A-----PSSNLHEYFRMPVKG-----------------VP--------------------------------I------------------------------------------------------------------TTTT------------------------------------------------------------------------------------------------------------------------------GSIPVLHGNCIPENVTSRFGG------TSSATPLVA----G---------------------------I------------------AALT----IS------------ANPHLS----------------------------------------------------------------------------------A------------------LEVISIL-------KSTASKN---------------------------------------------------------------------------------------------------------------------------------- 727
 728 ----------------------D----LN-----------VKNAW-------KQG-VTGQ--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQNY----------D--------------------------PDASYDVN-------D-GD--------------PDPQPRY---TQLN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVADN--------------------------------------------------------------DICG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------V--------VEA--------------------------QS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-KLAKE-AFQR----GV-----I--------------------------------------------------------------------------EGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRM--------KDSCNCDGY--------TNSIYT---LS---IS--S------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GG----------------VN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--DSHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTSNPAHL-TT-N--------------------------DWK--------------------------------------------INGVGRRVS----------------------------------------- 728
 729 ----------------YNQDHLD----LN-----------VKNAW-------KQG-VTGQ--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQNY----------D--------------------------PDASYDVN-------D-GD--------------PDPQPRY---TQLN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVADN--------------------------------------------------------------DICG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------V--------VEA--------------------------QS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-KLAKE-AFQR----GV-----I--------------------------------------------------------------------------EGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRM--------KDSCNCDGY--------TNSIYT---LS---IS--S------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GG----------------VN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--DSHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTSNPAHL-TT-N--------------------------DWK--------------------------------------------INGVGRRVSH---------------------------------------- 729
 730 -------------WYLYNQDHLD----LN-----------VKNAW-------KQG-VTGQ--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQNY----------D--------------------------PDASYDVN-------D-GD--------------PDPQPRY---TQLN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVADN--------------------------------------------------------------DICG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------V--------VEA--------------------------QS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-KLAKE-AFQR----GV-----I--------------------------------------------------------------------------EGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRM--------KDSCNCDGY--------TNSIYT---LS---IS--S------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GG----------------VN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--DSHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTSNPAHL-TT-N--------------------------DWK--------------------------------------------INGVGRRVSH---------------------------------------- 730
 731 -------------WYLYNPSHGD----LN-----------VKEAW-------AQG-FTGR--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKNY----------D--------------------------PDASYDVN-------D-RD--------------PDPQPRY---TQLN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------GVCG---VGV--AYN-A----------KI-----------------G--G--V--RML-DGE---VTD-------------------------------------V--------VEA--------------------------QS--LSL--------------------------------------------NSQHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-KLAKE-AFLQ----GV-----T--------------------------------------------------------------------------EGRSGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------RDSCNCDGY--------TNSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Y-GSV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------LN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKK------CT--DSHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANMNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTSRPAHL-IT-N--------------------------DWR--------------------------------------------TNGVGRLVSH---------------------------------------- 731
 732 -----TDPKFPQQWYLSNPNQRD----LN-----------VQEAW-------QQG-YTGR--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EANY----------D--------------------------PAASYDVN-------D-QD--------------SDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GICG---VGV--AYN-A----------KI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFYR----GV-----S--------------------------------------------------------------------------QGRNGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Y-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NT-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 732
 733 -------------WYLYNTNQRD----LN-----------VRQAW-------EQG-YTGK--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EANY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GICG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------HS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Y-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWV--------------------------------------------TNGVGRKVSH---------------------------------------- 733
 734 -----TDPKFPQQWYLSGVTQRD----LN-----------VKEAW-------AQG-YTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------L-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 734
 735 ---------------LSGVTQRD----LN-----------VKEAW-------AQG-YTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------L-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 735
 736 ----------------------D----LN-----------VKEAW-------AQG-YTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------L-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 736
 737 -------------WYLSGVTQRD----LN-----------VKEAW-------AQG-YTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S-------------------------------------------------------------QAPPASDPGTHCPQGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------L-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 737
 738 ----------------------D----LN-----------VKDAW-------AQG-YTGR--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------L-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 738
 739 ----------------------D----LN-----------VKEAW-------AQG-FTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------F-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-D--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 739
 740 ----------------------D----LN-----------VKAAW-------AQG-YTGH--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-RLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------F-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VQTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 740
 741 ----------------------D----LN-----------VKEAW-------AQG-YTGR--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PGASFDVN-------D-QD--------------PDPQPRY---TQMN--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VEA--------------------------RS--LGL--------------------------------------------NPNHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPA-HLAEE-AFFR----GV-----S--------------------------------------------------------------------------QGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------F-GNV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GN----------------QN-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQK------CT--ESHTG------TSAFAPLAA----G---------------------------I------------------IALT----LE------------ANKNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTSKPAHL-NA-N--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 741
 742 --------------------VPTTIPSMR-----------VVEAW-------NEG-YSGK--------------------------D-V--SV--------------T--------------------ILD---------------------------D--------------GIEH-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HANY----------D--------------------------PLASSDIN-------S-HD--------------DDPAPRL---NPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCA---IGI--AFN-A----------KI-----------------GDTG--V--RML-DGE---VTD-------------------------------------A--------VES--------------------------AS--IGL--------------------------------------------RPEHVDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-KMAKL-AFEH----GV-----N--------------------------------------------------------------------------QGREGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRH--------QDNCNCDGY--------TDSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------R-GTR-PWYS-------------------------------------------------------------------EACSSTL------------------------AATYS-S-------------GR----------------SG-----------------------------DKQI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRHG------CT--NTHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTAKPDGL-SV-D--------------------------DWQ--------------------------------------------QNGVGKRGAVSH-------------------------------------- 742
 743 ---------------------------MR-----------VVEAW-------NEG-YSGK--------------------------D-V--SV--------------T--------------------ILD---------------------------D--------------GIEH-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HANY----------D--------------------------PLASSDIN-------S-HD--------------DDPAPRL---NPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCA---IGI--AFN-A----------KI-----------------G--G--V--RML-DGE---VTD-------------------------------------A--------VES--------------------------AS--IGL--------------------------------------------RPEHVDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-KMAKL-AFEH----GV-----N--------------------------------------------------------------------------QGREGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRH--------QDNCNCDGY--------TDSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------R-GTR-PWYS-------------------------------------------------------------------EACSSTL------------------------AATYS-S-------------GR----------------SG-----------------------------DKQI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRHG------CT--NTHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTA------------------------------------------------------------------------------------------------------------------------------------- 743
 744 --------------------------------------------W-------NEG-YSGK--------------------------D-V--SV--------------T--------------------ILD---------------------------D--------------GIEH-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HANY----------D--------------------------PLASSDIN-------S-HD--------------DDPAPRL---NPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCA---IGI--AFN-A----------KI-----------------GDTG--V--RML-DGE---VTD-------------------------------------A--------VES--------------------------AS--IGL--------------------------------------------RPEHVDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-KMAKL-AFEH----GV-----N--------------------------------------------------------------------------QGREGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRH--------QDNCNCDGY--------TDSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------R-GTR-PWYS-------------------------------------------------------------------EACSSTL------------------------AATYS-S-------------GR----------------SG-----------------------------DKQI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRHG------CT--NTHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRTAKPDGL-SV-D--------------------------DWQ--------------------------------------------QNGVGKRGAVSHAFGYGLMDA----------------------------- 744
 745 --------------------GLD----MN-----------VMGAW-------EQG-VTGK--------------------------R-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNY----------D--------------------------PDASFDVN-------S-HD--------------KDPQPHY---DYTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AKANN--------------------------------------------------------------NVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------S--------VEA--------------------------QS--LSL--------------------------------------------RNNHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-TLARK-AFYD----GI-----T--------------------------------------------------------------------------KGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRD--------GDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------GG-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKI------CT--VNHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPTL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VNTARKANL-DP-R--------------------------VWT--------------------------------------------TNGVGRQVS----------------------------------------- 745
 746 -------WYLHGEDLKKRGSGLD----MN-----------VMGAW-------EQG-VTGK--------------------------R-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNY----------D--------------------------PDASFDVN-------S-HD--------------KDPQPHY---DYTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AKANN--------------------------------------------------------------NVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------S--------VEA--------------------------QS--LSL--------------------------------------------RNNHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-TLARK-AFYD----GI-----T--------------------------------------------------------------------------KGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRD--------GDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------GG-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKI------CT--VNHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPTL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VNTARKANL-DP-R--------------------------VWT--------------------------------------------TNGVGRQVSH---------------------------------------- 746
 747 -------WYLHGEDLKKRGSGLD----MN-----------VMGAW-------EQG-VTGK--------------------------R-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNY----------D--------------------------PDASFDVN-------S-HD--------------KDPQPHY---DYTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AKANN--------------------------------------------------------------NVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------S--------VEA--------------------------QS--LSL--------------------------------------------RNNHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-TLARK-AFYD----GI-----T--------------------------------------------------------------------------KGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRD--------GDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------GG-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKI------CT--VNHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPTL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VNTARKANL-DP-R--------------------------VWT--------------------------------------------TNGVGRQVSH---------------------------------------- 747
 748 -------WYL------KRGSGLD----MN-----------VMGAW-------EQG-VTGK--------------------------R-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MDNY----------D--------------------------PDASFDVN-------S-HD--------------KDPQPHY---DYTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AKANN--------------------------------------------------------------NVCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------S--------VEA--------------------------QS--LSL--------------------------------------------RNNHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-TLARK-AFYD----GI-----T--------------------------------------------------------------------------KGRGGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRD--------GDSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------GG-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKI------CT--VNHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPTL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VNTARKANL-DP-R--------------------------VWT--------------------------------------------TNGVGRQVSH---------------------------------------- 748
 749 ---------------------LD----MN-----------VMHAW-------EKG-FTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRNY----------D--------------------------PEASYDVN-------S-MD--------------PDPQPRY---DYSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AEAGN--------------------------------------------------------------GICS---VGV--AYN-A----------SI-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------SS--LGR--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-ALARK-AFAD----GI-----S--------------------------------------------------------------------------KGRQGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------GDSCSCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------H-GYI-PWYS-------------------------------------------------------------------EACSSTL------------------------ASTYS-S-------------GS----------------GN-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKS------CT--ELHTG------TSASAPLAA----G---------------------------I------------------IALA----LQ------------ANPSL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VMTARPANL-KA-E--------------------------DWI--------------------------------------------TNGMGRRVS----------------------------------------- 749
 750 --------------------GID----MN-----------ILPAW-------EAG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIER-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MKNY----------R--------------------------KNASYDVN-------G-KD--------------DDPEPRY---NFSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AQANN--------------------------------------------------------------SICS---VGV--AYN-A----------GI-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------QS--LSL--------------------------------------------NPQIIDI-----------------------------------------YSASWGPDD----D-GQ--------------------------------------------------------------TVDGPG-KLAKI-AFLN----GT-----T--------------------------------------------------------------------------LGRDGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------DDSCGCDGY--------TNSIFT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------N-GGV-PWYS-------------------------------------------------------------------ENCASTL------------------------ATTYS-S-------------GS----------------GT-----------------------------EKQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKK------CT--DSHSG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPQL----------------------------------------------------------------------------------NW------------------RDLQHII-------VMTSRPDNI-HT-S--------------------------DWT--------------------------------------------VNGVGRSVS----------------------------------------- 750
 751 --------------------GKD----MN-----------IVLAW-------EKG-YSGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IDNY----------D--------------------------SDASYDVN-------S-HD--------------SDPSPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----SQANN--------------------------------------------------------------NVCG---VGA--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------QS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-QMAKK-AFLD----GV-----T--------------------------------------------------------------------------KGRGGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------HDSCNCDGY--------TNSIYT---LS---IS--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------T-GSI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------GS-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHKK------CT--DRHSG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPKL----------------------------------------------------------------------------------TW------------------RDMQYIV-------VITSRSENL-NA-N--------------------------DWV--------------------------------------------TNGGGYHIS----------------------------------------- 751
 752 --------------------GLD----MN-----------VQEAW-------AEG-ITGK--------------------------G-S--VV--------------T--------------------ILD---------------------------D--------------GLEK-D------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRNY----------D--------------------------PMASFDVN-------D-HD--------------DDPSPRY---DATD--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AQGNN--------------------------------------------------------------SICA---VGI--AFN-A----------NI-----------------G--G--I--RML-DGE---VTD-------------------------------------A--------VEA--------------------------HS--LSH--------------------------------------------NSQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELATR-AFLE----GI-----R--------------------------------------------------------------------------KGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKE--------RDNCNCDGY--------TNSIWT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GAV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATAYS-S-------------GA----------------AD-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHS------CT--PSHTG------TSAAAPLAA----G---------------------------I------------------CALA----LE------------ANRNL----------------------------------------------------------------------------------NW------------------RDMQHIV-------VRTAKPDHL-IA-R--------------------------DWQ--------------------------------------------VNGVGRNVS----------------------------------------- 752
 753 --------------------GLD----MN-----------VREAW-------AEG-VTGK--------------------------G-T--VV--------------T--------------------ILD---------------------------D--------------GLEK-D------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRNY----------D--------------------------PLASYDVN-------N-HD--------------EDPMPRY---DLID--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AEGNN--------------------------------------------------------------SICA---VGV--AFD-A----------GI-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------RS--LSL--------------------------------------------NPHHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELATR-AFIE----G----------------------------------------------------------------------------------GRGGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRD--------HDNCNCDGY--------TNSIWT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYV-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GS----------------SG-----------------------------EKQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHS------CT--ASHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANRNL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VRTAKPANL-KA-D--------------------------DWQ--------------------------------------------VNGVGRNVS----------------------------------------- 753
 754 ----------------------D----HN-----------VKEAW-------DLG-YTGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLER-T------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPNY----------D--------------------------ERASYDVN-------D-RD--------------NDPMPRY---EFSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIFNN--------------------------------------------------------------SLCI---VGI--AYN-A----------NI-----------------G--G--I--RML-DGD---VTD-------------------------------------A--------VEA--------------------------AS--VGH--------------------------------------------NADYIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-KLTRS-AFEK----GI-----T--------------------------------------------------------------------------MGRKGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKD--------ADSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GA----------------TG-----------------------------EKMI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHA------CT--NMHTG------TSASAPLAA----G---------------------------I------------------VALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------IRTAKPINL-RA-G--------------------------DWT--------------------------------------------TNGVGRNVS----------------------------------------- 754
 755 ----------------------D----HN-----------VKEAW-------DLG-YTGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLER-T------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPNY----------D--------------------------ERASYDVN-------D-RD--------------NDPMPRY---EFSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIFNN--------------------------------------------------------------SLCI---VGI--AYN-A----------NI-----------------G--G--I--RML-DGD---VTD-------------------------------------A--------VEA--------------------------AS--VGH--------------------------------------------NADYIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPA-KLTRS-AFEK----GI-----T--------------------------------------------------------------------------MGRKGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKD--------ADSCNCDGY--------TNSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNI-PWYS-------------------------------------------------------------------EACSSTL------------------------ATTYS-S-------------GA----------------TG-----------------------------EKMI------------------------------------------------------------------LT--------------------------------------------------------------------------------------------------------------------------------TDLHHA------CT--NMHTG------TSASAPLAA----G---------------------------I------------------VALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------IRTAKPINL-RA-G--------------------------DWT--------------------------------------------TNGVGRNVS----------------------------------------- 755
 756 --------------------GPD----MN-----------VGPAW-------QKG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIQR-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ALNY----------D--------------------------PAASYDIN-------G-ND--------------SDPMPR-----DNG--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AVAFN--------------------------------------------------------------QYCG---VGV--AYN-A----------SI-----------------G--G--V--RML-DGT---VND-------------------------------------A--------VEA--------------------------KA--LGL--------------------------------------------YPDHIDI-----------------------------------------YSASWGPED----D-GS--------------------------------------------------------------TVDGPG-PLARR-AFIF----GV-----T--------------------------------------------------------------------------SGRQGKGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRY--------TDSCNCDGY--------TNSIFT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------G-GYK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GTP---------------GH-----------------------------DKSV------------------------------------------------------------------AT--------------------------------------------------------------------------------------------------------------------------------VDMDGSLRPDRICT--VEHTG------TSASAPLAA----G---------------------------I------------------AALA----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDMQYLV-------VLTSRSDPL-EK-E-------------------------PGWI--------------------------------------------LNGVKRKVS----------------------------------------- 756
 757 --------------------GLD----MN-----------VGPAW-------QKG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIQT-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQNY----------D--------------------------PEASFDIN-------G-ND--------------SDPTPQ-----DNG--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AVAFN--------------------------------------------------------------NFCG---VGV--AYN-A----------SI-----------------G--G--V--RML-DGK---VND-------------------------------------V--------VEA--------------------------QA--LSL--------------------------------------------NPSHIDI-----------------------------------------YSASWGPED----D-GS--------------------------------------------------------------TVDGPG-PLARR-AFIY----GV-----T--------------------------------------------------------------------------SGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRY--------TDSCNCDGY--------TNSIFT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------A-GFK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GTP---------------GH-----------------------------DKSV------------------------------------------------------------------AT--------------------------------------------------------------------------------------------------------------------------------VDMDGSLRPDHICT--VEHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQYLV-------VYTSRPAPL-EK-E-------------------------NGWT--------------------------------------------LNGVKRKYS----------------------------------------- 757
 758 --------------------GFD----MN-----------VIPAW-------RKG-YSGK--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GIQT-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AQNY----------D--------------------------PLASSDIN-------D-ND--------------NDPMPR-----DNG--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AVAFN--------------------------------------------------------------SYCG---VGI--AFN-A----------SI-----------------G--G--V--RML-DGT---VND-------------------------------------A--------VEA--------------------------RA--LSL--------------------------------------------NPDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPG-PLAKR-AFIN----GI-----M--------------------------------------------------------------------------KGRKGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRH--------DDSCNCDGY--------TNSIFT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------G-GFK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GRP---------------DV-----------------------------DRSI------------------------------------------------------------------AT--------------------------------------------------------------------------------------------------------------------------------VDMDGSLRPEFLCT--SDHTG------TSASAPLAA----G---------------------------I------------------CALA----LE------------ANSNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VFTSRPDPL-H--D-------------------------NGWV--------------------------------------------TNGIGKKVS----------------------------------------- 758
 759 ----------------NRGGGLD----MN-----------VIPAW-------KMG-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLES-D------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNY----------D--------------------------PKASYDVN-------S-HD--------------DDPMPHY---DMTD--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SFCA---VGI--AYG-A----------SV-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------RS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELASR-AFIE----GT-----T--------------------------------------------------------------------------KGRGGKGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------QDNCNCDGY--------TNSIWT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------E-GHV-PWYS-------------------------------------------------------------------EKCSSTL------------------------ATTYS-S-------------GG----------------QG-----------------------------EKQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHS------CT--VSHTG------TSASAPLAA----G---------------------------I------------------AALV----LQ------------SNQNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------VRTAKPANL-KD-P--------------------------SWS--------------------------------------------RNGVGRRVSH---------------------------------------- 759
 760 --------------------GLD----MN-----------VIPAW-------KMG-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLES-D------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNY----------D--------------------------PKASYDVN-------S-HD--------------DDPMPHY---DMTD--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SFCA---VGI--AYG-A----------SV-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------RS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELASR-AFIE----GT-----T--------------------------------------------------------------------------KGRGGKGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------QDNCNCDGY--------TNSIWT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------E-GHV-PWYS-------------------------------------------------------------------EKCSSTL------------------------ATTYS-S-------------GG----------------QG-----------------------------EKQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHS------CT--VSHTG------TSASAPLAA----G---------------------------I------------------AALV----LQ------------SNQNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------VRTAKPANL-KD-P--------------------------SWS--------------------------------------------RNGVGRRVS----------------------------------------- 760
 761 --------------------------------------------W-------KMG-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLES-D------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNY----------D--------------------------PKASYDVN-------S-HD--------------DDPMPHY---DMTD--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SFCA---VGI--AYG-A----------SV-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------VEA--------------------------RS--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELASR-AFIE----GT-----T--------------------------------------------------------------------------KGRGGKGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------QDNCNCDGY--------TNSIWT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------E-GHV-PWYS-------------------------------------------------------------------EKCSSTL------------------------ATTYS-S-------------GG----------------QG-----------------------------EKQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHS------CT--VSHTG------TSASAPLAA----G---------------------------I------------------AALV----LQ------------SNQNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------VRTAKPANL-KD-P--------------------------SWS--------------------------------------------RNGVGRRVSHSFGYGLMDAA------------------------------ 761
 762 --------------------GLD----MN-----------VIPAW-------KEG-VTGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLES-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHNY----------D--------------------------PYASYDVN-------S-SD--------------NDPMPHY---DLTD--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SKCA---VGI--AYG-A----------KV-----------------G--G--V--RML-DGD---VTD-------------------------------------I--------VEA--------------------------RS--LGH--------------------------------------------NSQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-ELATR-AFIE----GV-----R--------------------------------------------------------------------------NGRGGKGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------HDNCNCDGY--------TNSIWT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------E-GQV-PWFS-------------------------------------------------------------------EMCSSTL------------------------ATTYS-S-------------GN----------------TN-----------------------------EKQV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLHHT------CT--SSHTG------TSASAPLAA----G---------------------------I------------------AALV----LE------------ANRNL----------------------------------------------------------------------------------TW------------------RDLQHIV-------VRTAKPGNL-ID-P--------------------------NWS--------------------------------------------VNGVGRRVS----------------------------------------- 762
 763 ---------------------LD----VN-----------VIPVW-------KSG-ISGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GIEH-N------H-------------T---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ERNY----------D--------------------------PAASWDVN-------D-ND--------------PDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AQANN--------------------------------------------------------------SKCG---VGV--AYN-A----------RI-----------------G--G--V--RML-DGR---VTD-------------------------------------R--------VEA--------------------------ES--LSL--------------------------------------------NPQYIDI-----------------------------------------YSASWGPSD----D-GM--------------------------------------------------------------TVEGPG-TLASA-AFLN----GI-----T--------------------------------------------------------------------------KGRGGLGSIY--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRH--------DDSCNCDGY--------TASIYT---LS---IS--S------------------------------S---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--D--------H-GES-PWYS-------------------------------------------------------------------EACASTL------------------------ATTLS-S-------------GA----------------HG-----------------------------EKRI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHNQ------CT--ERHTG------TSASAPLAG----G---------------------------I------------------IALA----LE------------QNPKL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VHTANWIPL-KR-D-------------------------PEWR--------------------------------------------MNGIGLHVNEKFGF------------------------------------ 763
 764 ---------------------PSQDPNMG-----------VVEAW-------KLG-YTGK--------------------------G-V--SV--------------S--------------------ILD---------------------------D--------------GIEH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HANY----------D--------------------------ASASYDMN-------D-HD--------------SDPMPRA---TWTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCS---IGI--AFD-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------I--------VEG--------------------------LS--LSH--------------------------------------------ENNIIDI-----------------------------------------YSSSWGPDD----D-GK--------------------------------------------------------------TVDGPA-KLAYI-ALKQ----GV-----N--------------------------------------------------------------------------KGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRY--------QDNCNCDGY--------ASSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------H-GTI-PWYS-------------------------------------------------------------------EACSSTF------------------------ATTYS-S-------------GS----------------WQ-----------------------------HENI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLNHG------CT--ESHTG------TSASAPLAA----A---------------------------I------------------CALV----LE------------SNPNL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VRTA------------------------------------------------------------------------------------------------------------------------------------- 764
 765 --------------------------NMG-----------VVEAW-------KLG-YTGK--------------------------G-V--SV--------------S--------------------ILD---------------------------D--------------GIEH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HANY----------D--------------------------ASASYDMN-------D-HD--------------SDPMPRA---TWTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AVANN--------------------------------------------------------------GVCS---IGI--AFD-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------I--------VEG--------------------------LS--LSH--------------------------------------------ENNIIDI-----------------------------------------YSSSWGPDD----D-GK--------------------------------------------------------------TVDGPA-KLAYI-ALKQ----GV-----N--------------------------------------------------------------------------KGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRY--------QDNCNCDGY--------ASSIYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------H-GTI-PWYS-------------------------------------------------------------------EACSSTF------------------------ATTYS-S-------------GS----------------WQ-----------------------------HENI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLNHG------CT--ESHTG------TSASAPLAA----A---------------------------I------------------CALV----LE------------SNPNL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VRTAKPDGL-HT-S--------------------------GWI--------------------------------------------QNGAGRK--VCNSFGYGLLDAHAMV------------------------- 765
 766 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 766
 767 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 767
 768 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 768
 769 ----------------------E----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GHK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANNQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-S--------------------------DWK--------------------------------------------VNGAGHKVSHLYGFGLVDAEALV--------------------------- 769
 770 ------------------------------------------AAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GHK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------AK--------------------------------------------------------------------------------------------------------------------------SIP----------------------------------------------------------------------------------------------------------------------------------- 770
 771 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-S--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 771
 772 ---------------------SE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 772
 773 ---------------------SE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANNQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 773
 774 ----------MHCGDKNSRCRSE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 774
 775 -----------HCGDKNSRCRSE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANNQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVSH---------------------------------------- 775
 776 ---------------------SE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 776
 777 ---------------------SE----MN-----------VQAAW-------KKG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANNQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 777
 778 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 778
 779 ------------------------------------------AAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGI--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLAKQ-AFEY----GI-----K--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------AKSI------------------------------------------------------------------------------------------------------------PL-------VQVLRTTA--------------------------------------------------------------------------------------------------------------------------------- 779
 780 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGV--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGT--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLARQ-AFEH----GI-----R--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSVYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GHR-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERRI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 780
 781 --------------------------------------------------------------------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGV--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGT--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLARQ-AFEH----GI-----R--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSVYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GHR-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERRI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVSHLYGFGLVDADALVVEAKKWMAVPPQH-------------- 781
 782 ---------------------SE----MN-----------VQAAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------SYASYDVN-------G-ND--------------YDPSPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SYCI---VGV--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGT--------------------------------------------RPNYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-RLARQ-AFEH----GI-----R--------------------------------------------------------------------------KGRQGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSVYT---IS---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GHR-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERRI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANSQL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VKTSRPAHL-KA-N--------------------------DWK--------------------------------------------VNGAGHKVS----------------------------------------- 782
 783 ---------------------SE----MN-----------VVAAW-------QRG-YTGR--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNY----------D--------------------------PLASYDVN-------G-ND--------------HDPTPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SYCI---VGI--AYN-A----------RI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPDYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-LLAKQ-AFEH----GI-----K--------------------------------------------------------------------------KGRRGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRHR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VRTSRPVHL-RA-A--------------------------DWK--------------------------------------------TNGAGHKVS----------------------------------------- 783
 784 ---------------------SE----MN-----------VVAAW-------QRG-YTGR--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNY----------D--------------------------PLASYDVN-------G-ND--------------HDPTPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SYCI---VGI--AYN-A----------RI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPDYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-LLAKQ-AFEH----GI-----K--------------------------------------------------------------------------KGRRGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRHR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VRTSRPVHL-RA-A--------------------------DWK--------------------------------------------TNGAGHKVS----------------------------------------- 784
 785 ---------------------SE----MN-----------VVAAW-------QRG-YTGR--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNYWNLMVENPFQD--------------------------PLASYDVN-------G-ND--------------HDPTPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SYCI---VGI--AYN-A----------RI-----------------G--G--I--RML-DGD---VTD-------------------------------------V--------VEA--------------------------KS--LGI--------------------------------------------RPDYIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPG-LLAKQ-AFEH----GI-----K--------------------------------------------------------------------------KGRRGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDYCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GYK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GA----------------FY-----------------------------ERKIVSSALSGSAAPQVFVMYLQPLFWADDVETVVRVHYLCPGSMVSIELSMVSTGSTSGIVGLQLLSPQVT--------------------------------------------------------------------------------------------------------------------------------TDLRHR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLL-------VRTSRPVHL-RA-A--------------------------DWK--------------------------------------------TNGAGHKVS----------------------------------------- 785
 786 ---------------------SE----MN-----------IMAAW-------QRG-YTGK--------------------------D-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQNY----------D--------------------------PRASYDVN-------G-HD--------------EDPTPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SNCI---VGI--AYN-A----------RI-----------------G--G--I--RML-DGD---VTD-------------------------------------I--------VEA--------------------------KA--IGT--------------------------------------------KPDYIHI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPG-RLAKE-AFEK----GI-----K--------------------------------------------------------------------------EGRKGRGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNK-PWYL-------------------------------------------------------------------EECASTI------------------------ATTYS-S-------------GA----------------FY-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLL-------IKTSRPAHL-LA-P--------------------------DWK--------------------------------------------TNGVGRRVS----------------------------------------- 786
 787 ---------------------SE----MN-----------IMAAW-------QRG-YTGK--------------------------D-V--VV--------------T--------------------ILD---------------------------D--------------GIEK-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VQNY----------D--------------------------PRASYDVN-------G-HD--------------EDPTPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SNCI---VGI--AYN-A----------RI-----------------G--G--I--RML-DGD---VTD-------------------------------------I--------VEA--------------------------KA--IGT--------------------------------------------KPDYIHI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPG-RLAKE-AFEK----GI-----K--------------------------------------------------------------------------EGRKGRGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRE--------GDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-GNK-PWYL-------------------------------------------------------------------EECASTI------------------------ATTYS-S-------------GA----------------FY-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRKR------CT--DGHTG------TSVSAPMVA----G---------------------------I------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLL-------IKTSRPAHL-LA-P--------------------------DWK--------------------------------------------TNGVGRRVS----------------------------------------- 787
 788 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSY--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 788
 789 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSY--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 789
 790 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSY--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 790
 791 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSY--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 791
 792 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSY--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 792
 793 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 793
 794 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 794
 795 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 795
 796 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 796
 797 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 797
 798 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFK------------------------------------------- 798
 799 --------------------------------------------------------------------------------------------V--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVSHLYGFGLMDAEAMVMEAEKWTTVPQQHV------------- 799
 800 ------------CSDNTHPCQSD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 800
 801 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 801
 802 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 802
 803 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 803
 804 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 804
 805 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 805
 806 ---------------------SD----MN-----------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVS----------------------------------------- 806
 807 ----------------------------------------IEGAW-------KRG-YTGK--------------------------N-I--VV--------------T--------------------ILD---------------------------D--------------GIER-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------ALASCDVN-------G-ND--------------LDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--VSF--------------------------------------------NPQHVHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-PLTRQ-AFEN----GV-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DKKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DNHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGFKVSHLYGFGLMDAE------------------------------ 807
 808 ---------------------SD----MN-----------IVGAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------SQASFDVN-------G-ND--------------FDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------NPQHIHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLARQ-AFEN----GI-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------RDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDIQHII-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGYKVS----------------------------------------- 808
 809 ---------------------SD----MN-----------IVGAW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------SQASFDVN-------G-ND--------------FDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------NPQHIHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLARQ-AFEN----GI-----RMRLSVLVETQRELGDAASRQKNAATQQIGSTLTLHRAVASSSHTVQKSVEAGSKEILSLTSAFLKMLCSVVPVPMGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------RDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDIQHII-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAGGYK------------------------------------------- 809
 810 -------------------------------------------AW-------KRG-YTGK--------------------------N-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------SQASFDVN-------G-ND--------------FDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SHCT---VGI--AFN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------NPQHIHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLARQ-AFEN----GI-----R--------------------------------------------------------------------------MGRRGLGSVF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------RDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GKK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDIQHII-------VRTSRAGHL-NA-N--------------------------DWK--------------------------------------------TNAAGYKVSHLYGFGLMDA------------------------------- 810
 811 ---------------NTNLCQSD----MN-----------IVGAW-------RRG-YTGK--------------------------N-I--VI--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------PDASFDVN-------G-ND--------------IDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------THCI---VGI--AFN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------NPQHIHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLTRQ-AFEN----GV-----R--------------------------------------------------------------------------TGRNNLGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GRK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANRLL----------------------------------------------------------------------------------TW------------------RDIQHII-------VRTSRAGHL-IA-N--------------------------DWK--------------------------------------------TNAAGYKVS----------------------------------------- 811
 812 ---------------NTNLCQSD----MN-----------IVGAW-------RRG-YTGK--------------------------N-I--VI--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MQNY----------D--------------------------PDASFDVN-------G-ND--------------IDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------THCI---VGI--AFN-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------NPQHIHI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLTRQ-AFEN----GV-----R--------------------------------------------------------------------------TGRNNLGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------KDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GRK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GE----------------SY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANRLL----------------------------------------------------------------------------------TW------------------RDIQHII-------VRTSRAGHL-IA-N--------------------------DWK--------------------------------------------TNAAGYKVS----------------------------------------- 812
 813 ---------------------SD----MN-----------IVGAW-------KRG-YTGK--------------------------D-V--VV--------------T--------------------ILD---------------------------D--------------GIER-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IQNY----------D--------------------------NEASYDVN-------G-ND--------------VDPMPRY---DASN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ASANN--------------------------------------------------------------SHCT---VGI--AYN-A----------KI-----------------G--G--V--RML-DGD---VTD-------------------------------------M--------VEA--------------------------KS--LSL--------------------------------------------HPQHIDI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-SLARQ-AFEN----GI-----R--------------------------------------------------------------------------LGRKGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------RDHCSCDGY--------TNSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A--E--------S-GRK-PWYL-------------------------------------------------------------------EECSSTL------------------------TTTYS-S-------------GE----------------NY-----------------------------DRKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DSHTG------TSASAPMAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VKTSRAGHL-SA-P--------------------------DWK--------------------------------------------TNAAGYNVS----------------------------------------- 813
 814 ---------------------TD----MN-----------IQAAW-------RRG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIER-Q------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQNY----------D--------------------------ARASYDVN-------G-ND--------------PDPTPRY---DVTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGVVA----ASANN--------------------------------------------------------------SLCI---VGI--AYN-A----------KI-----------------G--G--V--RML-DGD---MTD-------------------------------------M--------VEA--------------------------QS--LNL--------------------------------------------RQQYIDI-----------------------------------------YSSSWGPDD----D-GR--------------------------------------------------------------TVDGPG-PLARL-ALEN----GI-----R--------------------------------------------------------------------------KGRKGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQS--------QDHCSCDGY--------TNSIYT---IS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------S-GRK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GD----------------SH-----------------------------SPGV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DEHSG------TSASAPMAA----G---------------------------I------------------IALT----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDIQHII-------VKTSSRGHL-SA-S--------------------------DWQ--------------------------------------------SNGAGYDVS----------------------------------------- 814
 815 -------------IHCDHNCLTD----MN-----------IQAAW-------RRG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIER-Q------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQNY----------D--------------------------ARASYDVN-------G-ND--------------PDPTPRY---DVTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGVVA----ASANN--------------------------------------------------------------SLCI---VGI--AYN-A----------KI-----------------G--G--V--RML-DGD---MTD-------------------------------------M--------VEA--------------------------QS--LNL--------------------------------------------RQQYIDI-----------------------------------------YSSSWGPDD----D-GR--------------------------------------------------------------TVDGPG-PLARL-ALEN----GI-----R--------------------------------------------------------------------------KGRKGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQS--------QDHCSCDGY--------TNSIYT---IS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------S-GRK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GD----------------SH-----------------------------SPGV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DEHSG------TSASAPMAA----G---------------------------I------------------IALT----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDIQHII-------VKTSSRGHL-SA-S--------------------------DWQ--------------------------------------------SNGAGYDVS----------------------------------------- 815
 816 ---------------------TD----MN-----------IQAAW-------RRG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIER-Q------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQNY----------D--------------------------ARASYDVN-------G-ND--------------PDPTPRY---DVTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGVVA----ASANN--------------------------------------------------------------SLCI---VGI--AYN-A----------KI-----------------G--G--V--RML-DGD---MTD-------------------------------------M--------VEA--------------------------QS--LNL--------------------------------------------RQQYIDI-----------------------------------------YSSSWGPDD----D-GR--------------------------------------------------------------TVDGPG-PLARL-ALEN----GI-----R--------------------------------------------------------------------------KGRKGRGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQS--------QDHCSCDGY--------TNSIYT---IS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------S-GRK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GD----------------SH-----------------------------SPGV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRQR------CT--DEHSG------TSASAPMAA----G---------------------------I------------------IALT----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDIQHII-------VKTSSRGHL-SA-S--------------------------DWQ--------------------------------------------SNGAGYDVS----------------------------------------- 816
 817 --------------------GYD----MN-----------VRQAW-------LQG-YAGR--------------------------N-V--SV--------------S--------------------ILD---------------------------D--------------GIQR-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASTDIN-------D-HD--------------DDPTPQ-------NNGDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ALAGN--------------------------------------------------------------NQCG---VGV--AFK-A----------KI-----------------G--G--V--RML-DGA---VSD-------------------------------------S--------VEA--------------------------AS--LSL--------------------------------------------NQDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TFDGPG-PLARE-AFYR----GI-----K--------------------------------------------------------------------------NGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSR--------QDSCSADGY--------TTSVYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Y--------D-NHR-PWYL-------------------------------------------------------------------EECPSSI------------------------ATTYS-S-------------AD----------------FR-----------------------------QPAI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------VDVPGG------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHLV-------LRTANWKPL-EN-N-------------------------PGWS--------------------------------------------RNGVGRMVS----------------------------------------- 817
 818 --------------------GYD----MN-----------VRQAW-------LQG-YAGR--------------------------N-V--SV--------------S--------------------ILD---------------------------D--------------GIQR-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASTDIN-------D-HD--------------DDPTPQ-------NNGDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ALAGN--------------------------------------------------------------NQCG---VGV--AFK-A----------KI-----------------G--G--V--RML-DGA---VSD-------------------------------------S--------VEA--------------------------AS--LSL--------------------------------------------NQDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TFDGPG-PLARE-AFYR----GI-----K--------------------------------------------------------------------------NGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSR--------QDSCSADGY--------TTSVYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Y--------D-NHR-PWYL-------------------------------------------------------------------EECPSSI------------------------ATTYS-S-------------AD----------------FR-----------------------------QPAI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------VDVPGG------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHLV-------LRTANWKPL-EN-N-------------------------PGWS--------------------------------------------RNGVGRMVS----------------------------------------- 818
 819 --------------------GYD----MN-----------VRQAW-------LQG-YAGR--------------------------N-V--SV--------------S--------------------ILD---------------------------D--------------GIQR-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASTDIN-------D-HD--------------DDPTPQ-------NNGDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ALAGN--------------------------------------------------------------NQCG---VGV--AFK-A----------KI-----------------G--G--V--RML-DGA---VSD-------------------------------------S--------VEA--------------------------AS--LSL--------------------------------------------NQDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TFDGPG-PLARE-AFYR----GI-----K--------------------------------------------------------------------------NGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSR--------QDSCSADGY--------TTSVYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Y--------D-NHR-PWYL-------------------------------------------------------------------EECPSSI------------------------ATTYS-S-------------AD----------------FR-----------------------------QPAI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------VDVPGG------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHLV-------LRTANWKPL-EN-N-------------------------PGWS--------------------------------------------RNGVGRMVS----------------------------------------- 819
 820 --------------------GYD----MN-----------VRQAW-------LQG-YAGR--------------------------N-V--SV--------------S--------------------ILD---------------------------D--------------GIQR-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PRASTDIN-------D-HD--------------DDPTPQ-------NNGDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ALAGN--------------------------------------------------------------NQCG---VGV--AFK-A----------KI-----------------G--G--V--RML-DGA---VSD-------------------------------------S--------VEA--------------------------AS--LSL--------------------------------------------NQDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TFDGPG-PLARE-AFYR----GI-----K--------------------------------------------------------------------------NGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSR--------QDSCSADGY--------TTSVYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Y--------D-NHR-PWYL-------------------------------------------------------------------EECPSSI------------------------ATTYS-S-------------AD----------------FR-----------------------------QPAI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------VDVPGG------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHLV-------LRTANWKPL-EN-N-------------------------PGWS--------------------------------------------RNGVGRMV------------------------------------------ 820
 821 --------------------GYD----MN-----------VRQAW-------LQG-YAGR--------------------------N-V--SV--------------S--------------------ILD---------------------------D--------------GIQR-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASTDIN-------D-HD--------------DDPTPQ-------NNGDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ALAGN--------------------------------------------------------------NQCG---VGV--AFK-A----------KI-----------------G--G--V--RML-DGA---VSD-------------------------------------S--------VEA--------------------------AS--LSL--------------------------------------------NQDHIDI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TFDGPG-PLARE-AFYR----GI-----K--------------------------------------------------------------------------NGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSS--------QDSCSADGY--------TTSVYT---LS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Y--------D-NHR-PWYL-------------------------------------------------------------------EECPSSI------------------------ATTYS-S-------------AD----------------FR-----------------------------QPAI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------VDVPGG------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHLV-------LRTANWKPL-EN-N-------------------------PGWS--------------------------------------------RNGVGRMVS----------------------------------------- 821
 822 ---------------------SD----MN-----------VEAAW-------KKG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIET-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AGNY----------D--------------------------PDASSDIN-------G-GT--------------LDPTPRY---EYTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMGNN--------------------------------------------------------------SFCS---VGV--AYK-A----------SI-----------------G--G--V--RML-DGD---VTD-------------------------------------S--------VEA--------------------------AS--LGL--------------------------------------------NPQHIMI-----------------------------------------YSASWGPDD----D-GK--------------------------------------------------------------TVDGPA-NLAKK-TFQA----GA-----K-------------------------------------------------------------------------------NASKL--C----------------YVQC-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRT--------HDSCGCDGY--------TNSIYT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------Q-GKV-PWYL-------------------------------------------------------------------EPCASTL------------------------ATTYS-S-------------GA----------------PH-----------------------------ERKV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLRKG------CT--ESHTG------TSASAPMAA----G---------------------------I------------------CALA----LE------------ANPML----------------------------------------------------------------------------------TW------------------RDLQYIV-------VMAA------------------------------------------------------------------------------------------------------------------------------------- 822
 823 --------------------GLT----MK-----------VKGAW-------DVG-YTGK--------------------------G-T--VV--------------T--------------------IVD---------------------------D--------------GLEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDNY----------D--------------------------QYASTDLN-------D-RD--------------PDPQPRA---TPNN--FN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TR-C-----------------------AGVVA----MRPNN--------------------------------------------------------------SICG---VGV--AYN-A----------HI-----------------G--G--I--RAL-DGR---VTD-------------------------------------S--------LEA--------------------------AS--VSH--------------------------------------------NPQHVDI-----------------------------------------YSSSWGPHD----D-GK--------------------------------------------------------------TVDGPR-RLGKR-AFID----GV-----T--------------------------------------------------------------------------SGRSGKGSIF--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGVN--------EDNCNYDGY--------QSSIYT---IS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--E--------Q-GTK-PGYV-------------------------------------------------------------------EKCSAVL------------------------TTTYS-S-------------GD----------------KF---------------------------DGTREI------------------------------------------------------------------CS--------------------------------------------------------------------------------------------------------------------------------SDEHHK------CT--KHHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPDL----------------------------------------------------------------------------------TW------------------RDVQHII-------VRTSKRYNLQDN-E-------------------------EGWT--------------------------------------------TNAAGFEVS----------------------------------------- 823
 824 ---------------LTEPKNRDDDLNMN-----------VIEAW-------DLG-YTGK--------------------------N-I--VV--------------S--------------------ILD---------------------------D--------------GLET-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDNY----------D--------------------------REASTDIN-------D-ND--------------SDPKPRF---TYSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----MKANN--------------------------------------------------------------DVCG---VGV--AYD-S----------KI-----------------G--G--I--RML-DGV---VTD-------------------------------------A--------VEA--------------------------AS--LSF--------------------------------------------NKQHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------TVDGPG-NLAKK-AFKD----GV-----T--------------------------------------------------------------------------EGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHN--------SDNCNCDGY--------QDSIYT---MS---IS--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------F-GNI-PWYL-------------------------------------------------------------------EQCSSTL------------------------ATTYS-S-------------GE----------------QG-----------------------------GSQI------------------------------------------------------------------SS--------------------------------------------------------------------------------------------------------------------------------TDLQHE------CT--DSHTG------TSASAPLAA----G---------------------------L------------------IALV----LE------------ANSAL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VMTSRRGNLIDK-D-------------------------PGWV--------------------------------------------TNGAG--------------------------------------------- 824
 825 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 825
 826 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 826
 827 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 827
 828 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 828
 829 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 829
 830 ----------------------D----LS-----------ILQAW-------SQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSK--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---VGV--AFN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHG------CT--DQHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASKPAHL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVSH---------------------------------------- 830
 831 ---------------------SD----LN-----------ILQVW-------SQG-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---AGV--AYN-T----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GHV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGAGRRVS----------------------------------------- 831
 832 ---------------------SD----LN-----------ILQVW-------SQG-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---AGV--AYN-T----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GHV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGAGRRVS----------------------------------------- 832
 833 ---------------------SD----LN-----------ILQVW-------SQG-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---AGV--AYN-T----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GHV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGAGRRVS----------------------------------------- 833
 834 ---------------MNNEMQSD----LN-----------ILQVW-------SQG-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---AGV--AYN-T----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GHV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGAGRRVS----------------------------------------- 834
 835 ----------------------D----LN-----------ILQVW-------SQG-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---AGV--AYN-T----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------Q-GHV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGAGRRVS----------------------------------------- 835
 836 ---------------------TDPWFPKQ-----------WYMVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 836
 837 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR---------------------------------------------------------------------------------------------- 837
 838 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR---------------------------------------------------------------------------------------------- 838
 839 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR---------------------------------------------------------------------------------------------- 839
 840 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 840
 841 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 841
 842 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 842
 843 ---------------------SD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 843
 844 ----------------NNKVLSD----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVSH---------------------------------------- 844
 845 ----------------------D----LN-----------ILQVW-------SQE-LSGQ--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------GFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ISD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-ILTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------N-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRQVS----------------------------------------- 845
 846 ----------------------D----LN-----------VLQVW-------SQG-LSGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPGD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------GFCG---AGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSVYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------E-GRA-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRRVS----------------------------------------- 846
 847 ----------------------D----LN-----------VLQVW-------SQG-LSGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPGD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------GFCG---AGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSVYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------E-GRA-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRRVS----------------------------------------- 847
 848 ----------------------D----LN-----------VLQVW-------SQG-LSGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPGD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------GFCG---AGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSVYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------E-GRA-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRRVS----------------------------------------- 848
 849 ----------------------D----LN-----------VLQVW-------SQG-LSGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPGD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------GFCG---AGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSVYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------E-GRA-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRRVS----------------------------------------- 849
 850 ----------------------D----LN-----------VLQVW-------SQG-LSGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPGD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------GFCG---AGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------KGRGGLGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSVYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------E-GRA-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GV----------------AT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------TNGVGRRVS----------------------------------------- 850
 851 ----------------------D----LN-----------IQQVW-------GQG-LSGQ--------------------------G-I--VV--------------S--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AMANN--------------------------------------------------------------RFCG---TGV--AYN-A----------RI-----------------G--G--V--RML-DGT---ITD-------------------------------------V--------IEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-VLTRE-AFRR----GV-----T--------------------------------------------------------------------------QGRGGRGTLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------R-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GA----------------AP-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------I------------------IALA----LE------------ANPFL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAQL-QA-E--------------------------DWT--------------------------------------------TNGVGRQVS----------------------------------------- 851
 852 ---------------------QD----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANEPP----------------------------------------------------------------------------------LW------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 852
 853 ---------------------QD----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------INGVGRQ------------------------------------------- 853
 854 ---------------------QD----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------INGVGRQ------------------------------------------- 854
 855 ---------------------QD----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------INGVGRQ------------------------------------------- 855
 856 ---------------------QD----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------INGVGRQ------------------------------------------- 856
 857 ----------------------D----LN-----------ILKAW-------NQG-LTGR--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------WANY----------D--------------------------PLASYDFN-------D-YD--------------PDPQPRY---TPND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVS----ATANN--------------------------------------------------------------GFCG---AGV--AFN-A----------RI-----------------G--G--V--RML-DGA---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------QPQHIHI-----------------------------------------YSASWGPED----D-GR--------------------------------------------------------------TVDGPG-LLTQE-AFRR----GV-----T--------------------------------------------------------------------------KGRQGLGTLF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLH--------YDNCNCDGY--------TNSIHT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--R--------Q-GRV-PWYS-------------------------------------------------------------------EACASTF------------------------TTTFS-S-------------GV----------------VT-----------------------------DPQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHQ------CT--DKHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VRASRPAQL-QA-E--------------------------DWR--------------------------------------------INGVGRQVS----------------------------------------- 857
 858 ----------------------D----LE-----------VLSAW-------RRG-YTGA--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GLEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASYDFN-------D-XD--------------PDPQSRY---NSWD--DP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------AGEVA----AVADN--------------------------------------------------------------DVCG---AGV--AHR-A----------RI-----------------G--G--V--RML-DGS---VTD-------------------------------------V--------VEA--------------------------RS--LSL--------------------------------------------RPQHIHI-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPG-FLAAE-AFRK----GV-----L--------------------------------------------------------------------------GGRSGLGSLF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLR--------RDDCNCDGY--------TNSPYT---LS---VG--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------G-GRV-PWYS-------------------------------------------------------------------EACASTL------------------------TTTYS-S-------------GA----------------KG-----------------------------ERQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLRHT------CT--GSHTG------TSASAPLAA----G---------------------------M------------------IALA----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VRASRPAHL-QA-D--------------------------DWA--------------------------------------------TNGVGRKVS----------------------------------------- 858
 859 -----TDPWFPKQWYMNNDIGFD----LN-----------ILAAW-------SKG-YTGR--------------------------G-V--VL--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASYDFN-------S-ND--------------PDPQPRY---DAWD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEAA----AVANN--------------------------------------------------------------GICG---AGI--AYN-A----------KI-----------------G--G--V--RML-DGP---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------RPQHIHI-----------------------------------------YSASWGPLD----D-GR--------------------------------------------------------------HVDGPG-VLALK-AFHN----GI-----T--------------------------------------------------------------------------KGRGGLGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIN--------YDNCNCDGY--------TNSIYT---LT---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F--A--------S-GRR-PRYS-------------------------------------------------------------------EPCASTL------------------------TTTYS-S-------------ST----------------SS-----------------------------KAQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DRHAG------SSASAPLAA----G---------------------------M------------------VALA----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDVQHLA-------VRASRPAHL-QA-E--------------------------DWA--------------------------------------------VNGVGRKVS----------------------------------------- 859
 860 ----------PKQWYMNNDIGFD----LN-----------ILAAW-------SKG-YTGR--------------------------G-V--VL--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASYDFN-------S-ND--------------PDPQPRY---DAWD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEAA----AVANN--------------------------------------------------------------GICG---AGI--AYN-A----------KI-----------------G--G--V--RML-DGP---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------RPQHIHI-----------------------------------------YSASWGPLD----D-GR--------------------------------------------------------------HVDGPG-VLALK-AFHN----GI-----T--------------------------------------------------------------------------KGRGGLGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIN--------YDNCNCDGY--------TNSIYT---LT---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F--A--------S-GRR-PRYS-------------------------------------------------------------------EPCASTL------------------------TTTYS-S-------------ST----------------SS-----------------------------KAQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DRHAG------SSASAPLAA----G---------------------------M------------------VALA----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDVQHLA-------VRASRPAHL-QA-E--------------------------DWA--------------------------------------------VNGVG--------------------------------------------- 860
 861 -----TDPWFPKQWYMNNDIGFD----LN-----------ILAAW-------SKG-YTGR--------------------------G-V--VL--------------S--------------------ILD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PLASYDFN-------S-ND--------------PDPQPRY---DAWD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEAA----AVANN--------------------------------------------------------------GICG---AGI--AYN-A----------KI-----------------G--G--V--RML-DGP---ITD-------------------------------------I--------VEA--------------------------QS--LSL--------------------------------------------RPQHIHI-----------------------------------------YSASWGPLD----D-GR--------------------------------------------------------------HVDGPG-VLALK-AFHN----GI-----T--------------------------------------------------------------------------KGRGGLGSIF--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIN--------YDNCNCDGY--------TNSIYT---LT---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------F--A--------S-GRR-PRYS-------------------------------------------------------------------EPCASTL------------------------TTTYS-S-------------ST----------------SS-----------------------------KAQI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHHR------CT--DRHAG------SSASAPLAA----G---------------------------M------------------VALA----LE------------ANPAL----------------------------------------------------------------------------------TW------------------RDVQHLA-------VRASRPAHL-QA-E--------------------------DWA--------------------------------------------VNGVGRKVS----------------------------------------- 861
 862 -------WYLNGGGHRGNSGNYD----MS-----------VKGAW-------QMG-YTGK--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GIER-T------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KENY----------D--------------------------PYASYDVN-------N-HD--------------PDPIPRY---DPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AKANN--------------------------------------------------------------NKCV---VGA--AYN-S----------RI-----------------G--G--V--RML-DGD---VSD-------------------------------------A--------VEA--------------------------AS--LSF--------------------------------------------NRTHIDI-----------------------------------------YSASWGPDD----D-GR--------------------------------------------------------------VVDGPG-PLAKK-AFIT----GI-----E--------------------------------------------------------------------------QGRGGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSA--------FDSCNCDGY--------TNSIYT---LS---IS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------H-GRK-PWYL-------------------------------------------------------------------EECSSTL------------------------ATTYS-S-------------GA----------------YN-----------------------------EKQI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLHNQ------CT--SSHTG------TSASAPLAA----G---------------------------L------------------VALL----LE------------ANPSL----------------------------------------------------------------------------------TW------------------RDVQYIT-------LLTSNPEPM--E-D-------------------------GMWT--------------------------------------------TNGKNRKVS----------------------------------------- 862
 863 ----------------------D----LG-----------VVGAW-------RKG-YSGR--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GIEY-T------H-------------D---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQNY----------D--------------------------PDASIDIN-------G-HD--------------KDPIPRY---DDTD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----ATANN--------------------------------------------------------------SKCV---PGV--AFN-A----------RI-----------------G--G--V--RML-DGD---VSD-------------------------------------F--------VEA--------------------------QA--LSL--------------------------------------------NPQHIDI-----------------------------------------YSASWGPDD----N-GK--------------------------------------------------------------VVDGPA-KLAKE-AFIQ----GV-----L--------------------------------------------------------------------------NGRGGKGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSL--------SDSCSCDGY--------TNSIFT---LS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------H-NRK-PWYL-------------------------------------------------------------------EECASTL------------------------ATTYS-S-------------GEN---------------YH-----------------------------ERKV------------------------------------------------------------------MS--------------------------------------------------------------------------------------------------------------------------------TDLHNG------CT--DKHTG------TSASAPLAA----G---------------------------M------------------CALA----LE------------ANPEL----------------------------------------------------------------------------------TW------------------RDMQHIV-------LMSANHSPL-G--D-------------------------GQWI--------------------------------------------TNGVGRYVSHKYGYGLMNAEAMV--------------------------- 863
 864 --------------------GLD----MN-----------VRSVW-------ARG-YAGQ--------------------------S-V--VV--------------T--------------------ILD---------------------------D--------------GLET-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY----------D--------------------------PFASYDVN-------S-ND--------------DNPEPRYLTRDKSN--TN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AAANN--------------------------------------------------------------SVCG---LGI--AYR-A----------RI-----------------G--G--V--RML-DGD---VTD-------------------------------------A--------MES--------------------------RS--LSH--------------------------------------------QLQHIDV-----------------------------------------YSASWGPED----D-GK--------------------------------------------------------------TVDGPG-KLAQM-AFRN----GI-----Q--------------------------------------------------------------------------MGRRGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTS--------HDNCNCDGY--------TNSIYT---LG---VG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------H-GSV-PWYA-------------------------------------------------------------------ELCSSTL------------------------AVTYS-S-------------GG----------------RG-----------------------------ERGV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLNHT------CT--DNHSG------TSASAPLAA----G---------------------------I------------------CALT----LS------------ANPNL----------------------------------------------------------------------------------TW------------------RDLQYLV-------VYTARPDGL-YA-D--------------------------DWH--------------------------------------------VNGVGRRVS----------------------------------------- 864
 865 ----------------------N----MN-----------VMPVW-------DQG-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLEH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KANY----------D--------------------------AEASYDFN-------A-ND--------------HDPFPRY---DVTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ASLNN--------------------------------------------------------------V-CS---VGV--AYH-A----------KI-----------------G--G--V--RML-DGQ---VTD-------------------------------------I--------VEA--------------------------KS--LSF--------------------------------------------GYEHIDI-----------------------------------------YSSSWGPND----D-GK--------------------------------------------------------------TVDGPA-KLAKK-AFLN----GI-----A--------------------------------------------------------------------------KGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSY--------SDSCNCDGY--------VLSPFT---IA---IG--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------Y-NNF-PWYA-------------------------------------------------------------------ERCSSIM------------------------AITYS-S-------------GSS---------------N------------------------------EKKI------------------------------------------------------------------IS--------------------------------------------------------------------------------------------------------------------------------TDLHGL------CT--DSHTG------TSAAAPMAA----G---------------------------M------------------IALA----LE------------IRPDL----------------------------------------------------------------------------------TW------------------RDVQYII-------VYSS------------------------------------------------------------------------------------------------------------------------------------- 865
 866 ----------------------N----MN-----------VMPVW-------DQG-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLEH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KANY----------D--------------------------AEASYDFN-------A-ND--------------HDPFPRY---DVTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----ASLNN--------------------------------------------------------------V-CS---VGV--AYH-A----------KI-----------------G--G--V--RML-DGQ---VTD-------------------------------------I--------VEA--------------------------KS--LSF--------------------------------------------GYEHIDI-----------------------------------------YSSSWGPND----D-GK--------------------------------------------------------------TVDGPA-KLAKK-AFLN----GI-----A--------------------------------------------------------------------------KGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSY--------SDSCNCDGY--------VLSPFT---IA---IG--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------Y-NNF-PWYA-------------------------------------------------------------------ERCSSIM------------------------AITYS-S-------------GSS---------------N------------------------------EKKI------------------------------------------------------------------IS--------------------------------------------------------------------------------------------------------------------------------TDLHGL------CT--DSHTG------TSAAAPMAA----G---------------------------M------------------IALA----LE------------IRPDL----------------------------------------------------------------------------------TW------------------RDVQYII-------VYSSSSA---ID-D-------------------------DEWI--------------------------------------------TNGAGLRVSSKYGYGLLDGAALV--------------------------- 866
 867 -------------------------SSMR-----------IEEAW-------IAG-FHGE--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLET-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRNY----------D--------------------------RFASIDIN-------D-RD--------------TDPTPRY---DPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGVVA----AVLDN--------------------------------------------------------------HICI---VGV--AHG-A----------SI-----------------G--G--V--RML-DGE---VTD-------------------------------------R--------VEA--------------------------HS--LNF--------------------------------------------AQDRIDI-----------------------------------------YSASWGPDD----D-GE--------------------------------------------------------------TVEGPG-PLAKA-AFKS----GA-----K--------------------------------------------------------------------------YGRGGNGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHN--------KDSCSCDGY--------INSIYT---IG---IS--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------R-GNR-PWYL-------------------------------------------------------------------EGCASTL------------------------ATTYS-S-------------GE----------------IN-----------------------------EGKV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLHRR------CT--HEHTG------TSASAPMAA----G---------------------------I------------------IALM----LQ------------ANMAL----------------------------------------------------------------------------------TW------------------RDVQHVI-------V---------------------------------------------------------------------------------------------------------------------------------------- 867
 868 -------------------------SSMR-----------IEEAW-------IAG-FHGE--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLET-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IRNY----------D--------------------------RFASIDIN-------D-RD--------------TDPTPRY---DPSN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGVVA----AVLDN--------------------------------------------------------------HICI---VGV--AHG-A----------SI-----------------G--G--V--RML-DGE---VTD-------------------------------------R--------VEA--------------------------HS--LNF--------------------------------------------AQDRIDI-----------------------------------------YSASWGPDD----D-GE--------------------------------------------------------------TVEGPG-PLAKA-AFKS----GA-----K--------------------------------------------------------------------------YGRGGNGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHN--------KDSCSCDGY--------INSIYT---IG---IS--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------R-GNR-PWYL-------------------------------------------------------------------EGCASTL------------------------ATTYS-S-------------GE----------------IN-----------------------------EGKV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLHRR------CT--HEHTG------TSASAPMAA----G---------------------------I------------------IALM----LQ------------ANMAL----------------------------------------------------------------------------------TW------------------RDVQHVI-------VRTTKSQGL----------------------------HGHDWV--------------------------------------------VNGAGFNVS----------------------------------------- 868
 869 ---------------------LD----IN-----------VVKAW-------NLN-VTGA--------------------------G-V--VV--------------S--------------------ILD---------------------------D--------------GLEH-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SRNY----------D--------------------------SLASYDFN-------S-GD--------------SDPAPRY---SQDN--IN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEVA----AEINN--------------------------------------------------------------NVCG---AGV--AFN-A----------KV-----------------G--G--I--RML-DGD---VTD-------------------------------------A--------VEA--------------------------GS--LSY--------------------------------------------KPEHIDI-----------------------------------------YSSSWGPDD----D-GT--------------------------------------------------------------TVDGPG-QLALN-AFKA----GI-----E--------------------------------------------------------------------------KGRGGLGSIF--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRF--------QDYCSCDGY--------INSPYT---IS---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--N--------C-GMK-PWYS-------------------------------------------------------------------EACSGTL------------------------AVTYS-S-------------GDA---------------SG---------------------------QFDKQI------------------------------------------------------------------AT--------------------------------------------------------------------------------------------------------------------------------TDLHGT------CT--QSHTG------TSAAAPLAA----G---------------------------I------------------FALV----LE------------ANKKL----------------------------------------------------------------------------------TW------------------RDMQHLI-------VKTSKMVS--PK-D-------------------------DEWQ--------------------------------------------KNAAGYYVNPKFGF------------------------------------ 869
 870 -------WYLENTGQASGPPHLD----HN-----------IIPAW-------KSG-ATGI--------------------------G-I--VV--------------S--------------------ILD---------------------------D--------------GLYY-E------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRNY----------D--------------------------PEASFDIN-------G-ND--------------HDPTPRK---TGND--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEVA----AIANN--------------------------------------------------------------SICT---VGA--AYN-A----------KI-----------------G--G--I--RML-DGD---VTD-------------------------------------A--------VEA--------------------------TS--LSW--------------------------------------------KPQHIDI-----------------------------------------YSSSWGPED----D-GR--------------------------------------------------------------NIDGPG-PLAKK-AFID----GV-----N--------------------------------------------------------------------------KGRHGLGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSV--------HDNCNCDGY--------VISIYT---IS---IS--A------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--D--------T-GNV-PWYT-------------------------------------------------------------------ESCSSIL------------------------ATTFS-S-------------GN----------------NG-----------------------------QNKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------DDLHDR------CT--ESHTG------TSAAAPLAA----G---------------------------M------------------FALA----LE------------ANPRL----------------------------------------------------------------------------------TW------------------RDLQHIV-------VITSKPDKL-HT-D--------------------------DWT--------------------------------------------INGVGRKISN---------------------------------------- 870
 871 --------------------KLD----LH-----------VIPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDDCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRIT-----------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AN-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 871
 872 --------------------KLD----LH-----------VIPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AN-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 872
 873 -----------------ALPKLD----LH-----------VIPVW-------EKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DLTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AS-N-------------------------PGWK--------------------------------------------KNGAG--------------------------------------------- 873
 874 --------------------KLD----LH-----------VIPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YDNY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AN-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 874
 875 --------------------KLD----LH-----------VIPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEF----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AN-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 875
 876 --------------------KLD----LH-----------VIPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PEASYDFN-------D-ND--------------HDPFPRY---DLIN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------HKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SL--IGF--------------------------------------------NPGHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GV-----K--------------------------------------------------------------------------QGRQGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IN--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATSYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHND------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AN-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 876
 877 --------------------KLD----LH-----------VIPVW-------QKG-ITGR--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PRASYDFN-------D-ND--------------YDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------RKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPEHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GI-----K--------------------------------------------------------------------------QGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATAYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHNE------CT--GTHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTSEYDPL-AG-N-------------------------PGWK--------------------------------------------KNGAGLMVNSRFGF------------------------------------ 877
 878 --------------------KLD----LH-----------VIPVW-------QKG-ITGR--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YANY----------D--------------------------PRASYDFN-------D-ND--------------YDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------RKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------NPEHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GI-----K--------------------------------------------------------------------------QGRNGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATAYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHNE------CT--GTHTG------TSASAPLA-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 878
 879 --------------MTQSLPKLD----LH-----------VLPVW-------QKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YSNY----------D--------------------------PEASYDFS-------D-ND--------------QDPFPRY---DPTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQANN--------------------------------------------------------------LKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGF--------------------------------------------SPDHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GI-----K--------------------------------------------------------------------------KGRKGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSIYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATAYS-S-------------GD----------------YT-----------------------------DQKI------------------------------------------------------------------IS--------------------------------------------------------------------------------------------------------------------------------ADLHNE------CT--STHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHLV-------VWTS------------------------------------------------------------------------------------------------------------------------------------- 879
 880 -----------------SLPKLD----LH-----------VIPVW-------KKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPNY----------D--------------------------PAASYDFN-------D-ND--------------PDPFPRY---DSTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQADN--------------------------------------------------------------NKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGY--------------------------------------------NPDHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GI-----Q--------------------------------------------------------------------------KGRGGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSLYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATAYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHNE------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------QNPDL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VWTS------------------------------------------------------------------------------------------------------------------------------------- 880
 881 -----------------SLPKLD----LH-----------VIPVW-------KKG-ITGK--------------------------G-V--VI--------------T--------------------VLD---------------------------D--------------GLEW-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YPNY----------D--------------------------PAASYDFN-------D-ND--------------PDPFPRY---DSTN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MQADN--------------------------------------------------------------NKCG---VGV--AYN-S----------KV-----------------G--G--I--RML-DGI---VTD-------------------------------------A--------IEA--------------------------SS--IGY--------------------------------------------NPDHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-RLAQK-AFEY----GI-----Q--------------------------------------------------------------------------KGRGGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRQ--------GDNCDCDGY--------TDSLYT---IS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GLS-PWYA-------------------------------------------------------------------EKCSSTL------------------------ATAYS-S-------------GD----------------YT-----------------------------DQRI------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------ADLHNE------CT--ETHTG------TSASAPLAA----G---------------------------I------------------FALA----LE------------QNPDL----------------------------------------------------------------------------------TW------------------RDLQHLV-------VWTSEFDPL-AN-N-------------------------PGWK--------------------------------------------RNGAG--------------------------------------------- 881
 882 --------------------KLD----LH-----------VLPVW-------ARG-ITGK--------------------------G-I--VV--------------C--------------------VLD---------------------------D--------------GLEK-N------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANY----------D--------------------------PYASYDLN-------D-ED--------------DDPQPRY---DPTD--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MVANN--------------------------------------------------------------NKCG---VGI--AYN-S----------RI-----------------G--G--V--RML-DGR---VTD-------------------------------------H--------LEA--------------------------SA--IAF--------------------------------------------NHTYVDV-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-PLATK-AFEK----GI-----T--------------------------------------------------------------------------EGRGGKGVIY--A----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRL--------GDNCDCDGY--------TGSIYT---IS---IN--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------H-QHT-PWYA-------------------------------------------------------------------EKCASTI------------------------ASAYS-S-------------GA----------------YN-----------------------------DQRI------------------------------------------------------------------AS--------------------------------------------------------------------------------------------------------------------------------ADLHGR------CT--TQHTG------TSAAAPLAA----G---------------------------I------------------FALV----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDMQHII-------TWTAEYSSL-KD-N-------------------------PGWR--------------------------------------------KNGAGFWVNNAFGY------------------------------------ 882
 883 -----------------NLPKLD----LH-----------VLPVW-------RKG-ITGK--------------------------G-I--VV--------------A--------------------VLD---------------------------D--------------GIEK-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDNY----------D--------------------------PDASFDFN-------D-ND--------------ADPQPRY---EETN--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----MAANN--------------------------------------------------------------SECG---VGI--AFN-A----------RI-----------------G--G--V--RML-DGV---VTD-------------------------------------A--------VEA--------------------------NS--IGF--------------------------------------------NIQHVDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPE-KLARA-AFEK----GV-----R--------------------------------------------------------------------------EGRRGKGSIF--A----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSN--------GDNCDCDGY--------TSSIYT---VS---IS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------Q-GRS-PWYG-------------------------------------------------------------------EKCASTL------------------------ATAYS-S-------------GE----------------YK-----------------------------DQKI------------------------------------------------------------------SS--------------------------------------------------------------------------------------------------------------------------------TDLHHE------CT--DSHTG------TSAAAPLAA----G---------------------------V------------------LALA----LE------------ANPDL----------------------------------------------------------------------------------TW------------------RDVQHLI-------VWTSEYDPL-SG-N-------------------------PGWF--------------------------------------------QNGAGLWVNSRFG------------------------------------- 883
 884 --------------------KLD----LR-----------VIPVW-------NKN-ITGR--------------------------G-I--VV--------------A--------------------VLD---------------------------D--------------GLEW-K------H-------------S---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------D--------------------------PEASFDFNSDNENNGD-GD--------------SDPSPRY---DDDN--FN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEIA----MVANN--------------------------------------------------------------GKCG---VGV--AYE-A----------KI-----------------G--G--I--RML-DGT---VTD-------------------------------------T--------LEA--------------------------RA--LAF--------------------------------------------NHTYIDI-----------------------------------------YSASWGPND----D-GK--------------------------------------------------------------TVEGPG-MLALA-ALKK----GI-----E--------------------------------------------------------------------------EGRGGKGVLY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSA--------HDNCDCDGY--------TGSIYT---IS---IS--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Q--------G-LKT-PWYA-------------------------------------------------------------------EACSSTV------------------------ASTYS-S-------------GT----------------AS-----------------------------ELRI------------------------------------------------------------------TT--------------------------------------------------------------------------------------------------------------------------------TDLHDT------CT--PAHTG------TSASAPLAA----G---------------------------I------------------FALL----LQ------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQHLV-------VWTADPSLL-EC-E-------------------------NEFT--------------------------------------------TNHAGFKSNNHFGF------------------------------------ 884
 885 -------------------PKLD----LH-----------VLPVW-------KKG-ITGE--------------------------G-I--VV--------------T--------------------VLD---------------------------D--------------GFET-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TKNY----------D--------------------------KDACYDFN-------S-ND--------------ANPYPRY---NNPNNEEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------IGEIA----MEENN--------------------------------------------------------------NICG---VGV--AHG-A----------KI-----------------G--G--I--RML-DGT---VTD-------------------------------------V--------VEG--------------------------KS--LSF--------------------------------------------NRDYIDV-----------------------------------------YSASWGPND----D-GR--------------------------------------------------------------TVEGPG-PLAKK-AFED----GV-----K--------------------------------------------------------------------------FGRKGKGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGS--------GDNCDCDGY--------TDSIYT---IS---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--Q--------K-GNS-PWYA-------------------------------------------------------------------ERCSSTL------------------------GTTLS-S-------------GS----------------YQ-----------------------------ERKI------------------------------------------------------------------VS--------------------------------------------------------------------------------------------------------------------------------TDLHGK------CT--DSHTG------TSASAPLAA----G---------------------------V------------------IALL----LQ------------SNPDL----------------------------------------------------------------------------------TW------------------RDVQHII-------VWTS------------------------------------------------------------------------------------------------------------------------------------- 885
 886 --------------TNAALPRLD----LN-----------ILPVY-------DMG-YTGR--------------------------G-V--TV--------------V--------------------VLD---------------------------D--------------GLEG-T------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNNY----------N--------------------------SKVSFDMN-------D-DD--------------PDPSPRY-----GRGYFN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGEIA----MEANN--------------------------------------------------------------AKCG---VGV--AFN-V----------SI-----------------G--G--V--RML-DGP---VSD-------------------------------------R--------VEA--------------------------SS--LIY--------------------------------------------ALEMVDI-----------------------------------------YSASWGPSD----D-GK--------------------------------------------------------------TVEGPG-KLVRQ-AFYR----GV-----K--------------------------------------------------------------------------EGRKGKGAIY--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRV--------KDNCNCDGY--------VSSIYT---LS---IG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------Q-GDF-PWYG-------------------------------------------------------------------EQCASTM------------------------AVTYS-S-------------GA----------------YT-----------------------------DQKI------------------------------------------------------------------AT--------------------------------------------------------------------------------------------------------------------------------VDLNDT------CT--MDHTG------TSAAAPLAS----G---------------------------I------------------VALA----LE------------ANSNL----------------------------------------------------------------------------------TW------------------RDVQHLV-------PWTSEYGPLKDN-I--------------------------DWQ--------------------------------------------ENSAGFR------------------------------------------- 886
 887 --------------------RFD----IN-----------VLPVW-------QKN-ITGK--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GLEH-S------H-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KYSY----------D--------------------------PEASYDYN-------D-YD--------------NDPEPRY---DSRS--SN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEIT----MKPNN--------------------------------------------------------------KMCG---VGV--AFG-A----------RI-----------------G--G--I--RML-DGS---ITD-------------------------------------G--------VEA--------------------------SS--LGH--------------------------------------------NMQHVDI-----------------------------------------YSASWGPND----N-GR--------------------------------------------------------------TVDGPG-DIVMK-ILRK----GV-----T--------------------------------------------------------------------------KGRGGLGSIY--A----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRR--------GDNCNCDGY--------VNSIYT---IA---VS--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--Y--------N-GTP-PWYA-------------------------------------------------------------------EDCTPAL------------------------ASTYS-S-------------GA----------------DA-----------------------------LKKV------------------------------------------------------------------AS--------------------------------------------------------------------------------------------------------------------------------IDLRGG------CT--TSHTG------TSASAPMAA----G---------------------------I------------------YALV----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQHAT-------VWTSNRKNL--T-K-------------------------SGWA--------------------------------------------RNGASRLYHHKFGF------------------------------------ 887
 888 --------------------GHD----LN-----------LLPVW-------RRG-ITGK--------------------------G-V--VI--------------S--------------------ILD---------------------------D--------------GIEH-T------H-------------P---------E--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KGNY----------D--------------------------SRASFDFN-------S-ND--------------TDPSPRS---NWRE--DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGVAA----AVANN--------------------------------------------------------------SNCI---VGV--AYE-A----------RI-----------------G--G--I--RML-DGE---ITD-------------------------------------L--------IEA--------------------------QS--LSH--------------------------------------------ERGYIDI-----------------------------------------YSSSWGPQD----D-GE--------------------------------------------------------------TVEGPG-FLTQI-ALEF----GA-----K--------------------------------------------------------------------------YGRQGKGSIV--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKY--------HDNCNCDGY--------TNSIYT---IS---VS--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--S--------V-GAQ-PLYS-------------------------------------------------------------------ESCASTL------------------------VSAYS-S-------------GTT---------------KF-----------------------------DRRV------------------------------------------------------------------MT--------------------------------------------------------------------------------------------------------------------------------TDLNQG------CT--DSHTG------TSVSPPIIA----G---------------------------L------------------IALA----LQ------------VNPKL----------------------------------------------------------------------------------TW------------------RDVQHIL-------VESS------------------------------------------------------------------------------------------------------------------------------------- 888
 889 -----------------SRPTAS----MN-----------IQQAW-------DMG-YTGA--------------------------G-I--VI--------------T--------------------IMD---------------------------D--------------GLEY-T------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNNY----------D--------------------------SEASYDFV-------S-RD--------------ADPIPVYIPMKE----DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHG-------TR-C-----------------------AGEIV----MQPNN--------------------------------------------------------------SKCG---VGI--AFG-A----------QI-----------------G--G--I--RML-DLM---ITD-------------------------------------E--------MEG--------------------------SS--LSF--------------------------------------------NLQHVDI-----------------------------------------YSASWGPDD----G-GY--------------------------------------------------------------TVEGPA-EITQT-AMRT----GV-----A--------------------------------------------------------------------------NGRDGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGAD--------HDDCNADGY--------ANSIYT---LV---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-QDR-PFYS-------------------------------------------------------------------EHCSASL------------------------ASTYS-S-------------GN----------------KN-----------------------------QKMV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHNQ------CI--GNFSG------TSASAPMAA----G---------------------------I------------------ISLA----LQ------------ANGNL----------------------------------------------------------------------------------TW------------------RDVQYLV-------VITSKRHQL-----------------------------SGEWT--------------------------------------------TNGAGYEAS----------------------------------------- 889
 890 ---------MDGNFTGDSRPTAS----MN-----------IQQAW-------DMG-YTGA--------------------------G-I--VI--------------T--------------------IMD---------------------------D--------------GLEY-T------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNNY----------D--------------------------SEASYDFV-------S-RD--------------ADPIPVYIPMKE----DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHG-------TR-C-----------------------AGEIV----MQPNN--------------------------------------------------------------SKCG---VGI--AFG-A----------QI-----------------G--G--I--RML-DLM---ITD-------------------------------------E--------MEG--------------------------SS--LSF--------------------------------------------NLQHVDI-----------------------------------------YSASWGPDD----G-GY--------------------------------------------------------------TVEGPA-EITQT-AMRT----GV-----A--------------------------------------------------------------------------NGRDGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGAD--------HDDCNADGY--------ANSIYT---LV---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-QDR-PFYS-------------------------------------------------------------------EHCSASL------------------------ASTYS-S-------------GN----------------KN-----------------------------QKMV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHNQ------CI--GNFSG------TSASAPMAA----G---------------------------I------------------ISLA----LQ------------ANGNL----------------------------------------------------------------------------------TW------------------RDVQYLV-------VITSKRHQL-----------------------------SGEWT--------------------------------------------TNGAGYEAS----------------------------------------- 890
 891 ----------------------------N-----------IQQAW-------DMG-YTGA--------------------------G-I--VI--------------T--------------------IMD---------------------------D--------------GLEY-T------H-------------T---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNNY----------D--------------------------SEASYDFV-------S-RD--------------ADPIPVYIPMKE----DN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------MHG-------TR-C-----------------------AGEIV----MQPNN--------------------------------------------------------------SKCG---VGI--AFG-A----------QI-----------------G--G--I--RML-DLM---ITD-------------------------------------E--------MEG--------------------------SS--LSF--------------------------------------------NLQHVDI-----------------------------------------YSASWGPDD----G-GY--------------------------------------------------------------TVEGPA-EITQT-AMRT----GV-----A--------------------------------------------------------------------------NGRDGKGSIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGAD--------HDDCNADGY--------ANSIYT---LV---VS--S------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-QDR-PFYS-------------------------------------------------------------------EHCSASL------------------------ASTYS-S-------------GN----------------KN-----------------------------QKMV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLHNQ------CI--GNFSG------TSASAPMAA----G---------------------------I------------------ISLA----LQ------------ANGNL----------------------------------------------------------------------------------TW------------------RDVQYLV-------VITSKRHQL-----------------------------SGEWT--------------------------------------------TNGAGYEAS----------------------------------------- 891
 892 --------------------GYD----MN-----------VLEAW-------ELG-YTGK--------------------------G-I--KI--------------T--------------------IMD---------------------------D--------------GIDY-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVTY----------D--------------------------PKASIDIN-------G-HD--------------NDPMPNI------RNRDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGQIA----AQGNN--------------------------------------------------------------SVCI---VGI--AHN-A----------QI-----------------G--G--I--RML-DGY---ITD-------------------------------------R--------VEA--------------------------ET--LHF--------------------------------------------RQDYIDI-----------------------------------------YSGSWGPED----S-GK--------------------------------------------------------------LYEGPG-ILAQS-AFQQ----GV-----V--------------------------------------------------------------------------TGRRGFGNIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSL--------DDSCACDGY--------SSSPFT---LS---VS--G------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--E--------S-NTR-PWYL-------------------------------------------------------------------EKCSSTL------------------------ASTYS-S-------------GS---------------------------------------------PMERMI------------------------------------------------------------------ST--------------------------------------------------------------------------------------------------------------------------------TDLGHD------CT--RMHSG------TSACAPMAA----G---------------------------I------------------IALL----LE------------ANGRL----------------------------------------------------------------------------------SW------------------RDVQYIT-------LLTANPKPFKDG----------------------------NFT--------------------------------------------KNAVGREYSQLYGYGLMDAGKMV--------------------------- 892
 893 ---------------------VD----MN-----------VVPVW-------KKN-ITGR--------------------------G-I--VI--------------S--------------------VLD---------------------------D--------------GLDW-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EANY----------D--------------------------QTASIDLN-------D-ND--------------NDPMPRD------SDADN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHG-------TR-C-----------------------AGEAA----AIANN--------------------------------------------------------------GICG---TGV--AYN-A----------KI-----------------G--G--V--RML-DGQ---ATD-------------------------------------A--------LEA--------------------------SA--LGF--------------------------------------------RGDHIDI-----------------------------------------YINCWGPKD----D-GK--------------------------------------------------------------TFGKPG-PMAAK-ALRL----GA-----E--------------------------------------------------------------------------QGRNRLGSIF--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLT--------DDDCNCDGY--------TTSIFT---IS---IG--C------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--D--------H-GLS-AYYT-------------------------------------------------------------------EKCSSTL------------------------AVTFN-G-------------ASH---------------KE---------------------------GRENKM------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLYHQ------CT--EEFKG------TSASAPLAA----G---------------------------I------------------IALT----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQALI-------VHTAQITSPVDE-G---------------------------WK--------------------------------------------RNGAGFHFNHKFGF------------------------------------ 893
 894 --------------------GVD----IN-----------VRPVW-------EQG-ITGR--------------------------G-V--VV--------------S--------------------VLD---------------------------D--------------GVDH-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDNY----------D--------------------------QKASYDFN-------D-MD--------------ADPKPRD------SDPDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHG-------TR-C-----------------------AGEIA----AAANN--------------------------------------------------------------SNCG---VGV--AYD-A----------NI-----------------G--G--V--RML-DGQ---ATD-------------------------------------I--------LEG--------------------------SS--LSF--------------------------------------------QSNYIDI-----------------------------------------YSNCWGPKD----D-GK--------------------------------------------------------------TFGKPG-RLAQE-ALMR----GA-----L--------------------------------------------------------------------------EGRNGKGNIY--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLT--------DDDCNCDGY--------TTSIFT---IS---IG--C------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--D--------H-GLS-AYYT-------------------------------------------------------------------ELCSSTL------------------------AVTFN-G-------------GSH---------------RE---------------------------KEENKM------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDLHGK------CT--DEFKG------TSSSAPLAA----G---------------------------I------------------IALV----LQ------------ANPNL----------------------------------------------------------------------------------SW------------------RDVQHLI-------VNTAQVTSPVDE-G---------------------------WM--------------------------------------------DNGGGFHFN----------------------------------------- 894
 895 ---------------------MD----IN-----------IIPVW-------SRG-ISGK--------------------------N-I--VV--------------A--------------------VLD---------------------------D--------------GLDH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRNY----------D--------------------------PKASYDFN-------D-YD--------------EDPMPRT------SDPNN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------CHG-------TK-C-----------------------AGEVA----AEAGN--------------------------------------------------------------GICG---VGV--AFN-S----------SV-----------------G--G--I--RML-DGN---TTD-------------------------------------T--------IEG--------------------------SA--LSF--------------------------------------------KKDYIDI-----------------------------------------YSCAWGPKD----D-GK--------------------------------------------------------------RFGRPG-TLASK-ALEL----GV-----K--------------------------------------------------------------------------EGRNGLGSIF--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLT--------DDDCNCDGY--------TTSVYT---IS---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--D--------H-GLS-TYYT-------------------------------------------------------------------ESCASTL------------------------AVTFS-G-------------GSH---------------RE---------------------------KRENKI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TTLNHK------CT--DEFKG------TSSAAPLAA----G---------------------------M------------------IALM----LE------------ANRKL----------------------------------------------------------------------------------TW------------------RDVQHII-------VETSLMTSPLDE-G---------------------------WR--------------------------------------------RNGAGKWFNQKFGF------------------------------------ 895
 896 ----------------------D----DR-----------VLKVW-------EEG-ITGR--------------------------G-V--KV--------------S--------------------ILD---------------------------D--------------GMDH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY----------D--------------------------QQSSKDIN-------G-HD--------------DDPFPDD------TDPYN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHG-------TK-C-----------------------AGTVA----AVANN--------------------------------------------------------------SICG---VGI--AFN-A----------KI-----------------G--A--I--RML-DGK---ATD-------------------------------------L--------IEA--------------------------DA--LSY--------------------------------------------HRDHIDI-----------------------------------------YSCSWGPKD----N-GV--------------------------------------------------------------TFGRPG-PLGRL-ALAQ----GA-----K--------------------------------------------------------------------------DGRKGRGSLF--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGMN--------KDDCNADGY--------VNSIYT---LG---IG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--E--------H-GVS-TYYG-------------------------------------------------------------------EKCAAMI------------------------AVTYC-S-------------GAH------------SGSNG---------------------------DPQAVV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TYLHHQ------CT--DSFVG------TSSAAPLAA----G---------------------------I------------------FALV----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDIQHLV-------FQTAVKTSPMDL-G---------------------------WA--------------------------------------------VNGCGKPYN----------------------------------------- 896
 897 ----------------------D----LN-----------IKIAW-------DQG-YTGK--------------------------G-V--TV--------------T--------------------VLD---------------------------D--------------GIDH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKNY----------S--------------------------PFASADMN-------DKDD------------KQNDPMPDI------RTPGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGEIA----AEANN--------------------------------------------------------------SVCS---VGV--AYN-A----------QV-----------------G--G--V--RML-DGE---VYD-------------------------------------S--------IEA--------------------------KA--LNY--------------------------------------------KNQFIDV-----------------------------------------MSASWGPRD----D-GM--------------------------------------------------------------TMEGPG-PATKD-ALET----GV-----K--------------------------------------------------------------------------KGRNGKGIIY--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGVH--------DDDCGCDGY--------VSSPYS---LS---VG--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--D--------R-GQA-PYFD-------------------------------------------------------------------EKCASTL------------------------TVVPS-G-------------GEI----------RAGEFEG---------------------------QPKIKV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDINGG------CI--LGFEG------TSAAAPLAA----G---------------------------C------------------AALA----LE------------ANPDL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VETA------------------------------------------------------------------------------------------------------------------------------------- 897
 898 DPYYKDQWYCENNGQSGGTKYID----LN-----------IKIAW-------DQG-YTGK--------------------------G-V--TV--------------T--------------------VLD---------------------------D--------------GIDH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KKNY----------S--------------------------PFASADMN-------DKDD------------KQNDPMPDI------RTPGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGEIA----AEANN--------------------------------------------------------------SVCS---VGV--AYN-A----------QV-----------------G--G--V--RML-DGE---VYD-------------------------------------S--------IEA--------------------------KA--LNY--------------------------------------------KNQFIDV-----------------------------------------MSASWGPRD----D-GM--------------------------------------------------------------TMEGPG-PATKD-ALET----GV-----K--------------------------------------------------------------------------KGRNGKGIIY--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGVH--------DDDCGCDGY--------VSSPYS---LS---VG--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--D--------R-GQA-PYFD-------------------------------------------------------------------EKCASTL------------------------TVVPS-G-------------GEI----------RAGEFEG---------------------------QPKIKV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDINGG------CI--LGFEG------TSAAAPLAA----G---------------------------C------------------AALA----LE------------ANPDL----------------------------------------------------------------------------------TW------------------RDMQHIV-------VETAKIPSV-----------------------------DQTWV--------------------------------------------VNGAGKHVSHTFG------------------------------------- 898
 899 --------------------GID----LN-----------VIPVW-------KKG-LTGR--------------------------G-V--VV--------------T--------------------ILD---------------------------D--------------GVDH-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RENY----------L--------------------------AEASADLN-------SRSD--------------NDPMPDT------SSADN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGEVA----AKADN--------------------------------------------------------------GKCG---VGI--AYN-A----------NI-----------------G--G--V--RML-DGL---VTD-------------------------------------M--------LES--------------------------EA--ISF--------------------------------------------KRDLIDI-----------------------------------------YSASWGPPD----T-GD--------------------------------------------------------------TMEGPG-VYCKR-ALAD----GV-----R--------------------------------------------------------------------------LGRNGKGSIF--V----------------WATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGMV--------DDDCNCDGY--------VSSIET---IS---IG--S------------------------------M---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--D--------R-GLS-TYFS-------------------------------------------------------------------EVCLSTM------------------------AVVPC-G-------------GDH----------TITARRE---------------------------SDEKPH------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDLNGD------CT--LDFEG------TSSAAPMAA----G---------------------------A------------------FALV----LE------------ANPDL----------------------------------------------------------------------------------TW------------------RDLQHLV-------ARTARIPNDSEE-G---------------------------WT--------------------------------------------VNGGGLHVN----------------------------------------- 899
 900 -------------LINNKNRDMD----IN-----------VTGVW-------SRN-ITGH--------------------------G-V--TV--------------A--------------------VVD---------------------------D--------------GVEW-A------N-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDNY----------N--------------------------SAGSWDLN-------S-DD--------------PDPTPSA------SKDSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVP-N--------------------------------------------------------------SHCA---VGV--AYG-A----------KF-----------------S--G--L--KVL-DGP---MTD-------------------------------------S--------LEA--------------------------KA--FNK--------------------------------------------NSQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-VFAKA-AMQY----GI-----D--------------------------------------------------------------------------FGRRGFGSIY--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRF--------QDNCNYDGY--------ANSIYT---VT---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------D-GNM-PFYA-------------------------------------------------------------------EKCASML------------------------AVTFS-S-------------GT-----------------S---------------------------Q-HRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWTQRGGKG--CT--TAHSG------TSAAAPLAA----G---------------------------M------------------LALM----LQ------------ARPCL----------------------------------------------------------------------------------TW------------------RDIQYLI-------ILTAQKVD--ID-H-------------------------SEWK--------------------------------------------RNQAGLYHS----------------------------------------- 900
 901 ---------------------MD----LN-----------VLNVW-------KKN-ITGS--------------------------G-V--TV--------------A--------------------VID---------------------------D--------------GIEW-T------N-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNY----------S--------------------------PEGSFDLN-------S-ND--------------PDPMPEF-D----TKGQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVA-N--------------------------------------------------------------SVCA---VGV--AFH-A----------KI-----------------S--G--I--KIL-DGP---MTD-------------------------------------N--------LEA--------------------------AA--FNK--------------------------------------------NMHINDV-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TIDGPH-YLARK-ALLY----GV-----T--------------------------------------------------------------------------GGRQGYGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSA--------GDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------A-GGI-PYYA-------------------------------------------------------------------ESCSSML------------------------AVTFS-S-------------GD-----------------A---------------------------F-HKGI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWQMGKGTG--CT--TGHSG------TSAAAPLAA----G---------------------------M------------------VALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VLTAKLIN--EQ-S-------------------------SEWT--------------------------------------------VNAAGFYHSHQHGFGLMD-------------------------------- 901
 902 -------------LHNPS--GMD----IN-----------VTSVW-------ENG-ITGK--------------------------G-V--TV--------------S--------------------VID---------------------------D--------------GLEW-S------N-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDNY----------S--------------------------KEGSWDLN-------S-ND--------------ADPLPSV-D----SKGQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVP-N--------------------------------------------------------------TVCG---VGV--AYG-A----------KV-----------------S--G--I--RAL-DGP---MTD-------------------------------------S--------LEA--------------------------TA--FNK--------------------------------------------FMQINDI-----------------------------------------YSCSWGPDD----D-GE--------------------------------------------------------------TVDGPH-PLAKA-ALQH----GV-----S--------------------------------------------------------------------------AGRKGYGNIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRY--------EDNCNFDGY--------ANSIYT---ITVDNVG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------R-GHM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-S-------------GQ-----------------S---------------------------P-QRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWTLDGGTG--CT--MSHTG------TSAAAPLAA----G---------------------------L------------------VALM----LE------------ARPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VMTSTLVD--E------------------------------------------------------------------------------------------------------------------------------ 902
 903 -------------LDNLKFIGHD----IN-----------VTGVW-------ENN-ITGK--------------------------G-V--TV--------------S--------------------VID---------------------------D--------------GVEW-T------N-------------P---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LDNY----------S--------------------------AQGSWDLN-------S-ND--------------GDPMPRV-D----EAGLN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVA-N--------------------------------------------------------------EYCG---VGV--AFG-A----------KV-----------------S--G--I--RIL-DGP---MTD-------------------------------------S--------LEA--------------------------MA--FNT--------------------------------------------KSEVNDV-----------------------------------------YSCSWGPDD----N-GR--------------------------------------------------------------TVDGPH-QLAQA-ALAH----GV-----M--------------------------------------------------------------------------FGRKGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHF--------KDNCNFDGY--------ANSIFT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------L-GQM-PYYA-------------------------------------------------------------------EQCAAML------------------------AVTYS-S-------------GQ-----------------G---------------------------H-QRNI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWRLGTGTG--CT--DRHTG------TSAAAPLAA----G---------------------------V------------------IALM----LQ------------ARTCL----------------------------------------------------------------------------------TW------------------RDVQHLI-------VYTSVRID--ID-P-------------------------EEWQ--------------------------------------------VNGAGFAHS----------------------------------------- 903
 904 ----------------------D----IN-----------VTGVW-------EYG-ITGK--------------------------G-V--TT--------------A--------------------VID---------------------------D--------------GLEW-T------N-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RVNY----------S--------------------------PEGSWDLN-------S-ND--------------ADPMPHG-E----KEK-N----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVADN--------------------------------------------------------------SICG---VGV--AYG-A----------KV-----------------A--G--I--RVL-DGP---MTD-------------------------------------S--------LEA--------------------------TA--FMK--------------------------------------------GYTINDV-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-YLAMR-AMRL----GV-----D--------------------------------------------------------------------------YGRGGYGAIY--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQR--------GDNCNYDGY--------ANSIYT---LT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------V-GSM-PFYA-------------------------------------------------------------------EECASML------------------------AVTYS-S-------------GS-----------------G---------------------------PYQRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWMKDGGTG--CT--EGHTG------TSAAAPIAA----G---------------------------I------------------IALM----LE------------AQPCL----------------------------------------------------------------------------------TW------------------RDVQHLV-------VMTADKVD--VD-L-------------------------AHWT--------------------------------------------TNAAGLHHSHKHGFGLMN-------------------------------- 904
 905 --FTDPSYPNQWHLHNSKNAGMD----IN-----------VTGIW-------EHN-ITGL--------------------------G-V--TV--------------A--------------------VID---------------------------D--------------GLEW-T------N-------------E---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AENY----------C--------------------------AEGSWDLN-------S-ND--------------DNPAPEM-RIKDGKQSQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEIG----AAR-N--------------------------------------------------------------NVCG---VGV--SFS-S----------RV-----------------S--G--I--RLL-DGP---MTD-------------------------------------S--------LEA--------------------------TA--FNK--------------------------------------------FMYINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-TLAKA-ALQH----GV-----T--------------------------------------------------------------------------YGRRGRGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKN--------GDNCNYDGY--------ANSMYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------K-GQM-PFYA-------------------------------------------------------------------EECSSLF------------------------AVTFS-S-------------GS-----------------R---------------------------P-QRNI------------------------------------------------------------------LT--------------------------------------------------------------------------------------------------------------------------------TDWTLGPGTG--CT--NTHTG------TSAAAPLAA----G---------------------------M------------------ISLM----LE------------AKPCL----------------------------------------------------------------------------------SW------------------RDVQHII-------VYSALKID--QK-K-------------------------GEWT--------------------------------------------VNAAGFHHS----------------------------------------- 905
 906 -------------LHNSKNAGMD----IN-----------VTGIW-------EHN-ITGL--------------------------G-V--TV--------------A--------------------VID---------------------------D--------------GLEW-T------N-------------E---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AENY----------C--------------------------AEGSWDLN-------S-ND--------------DNPAPEM-RIKDGKQSQN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEIG----AAR-N--------------------------------------------------------------NVCG---VGV--SFS-S----------RV-----------------S--G--I--RLL-DGP---MTD-------------------------------------S--------LEA--------------------------TA--FNK--------------------------------------------FMYINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-TLAKA-ALQH----GV-----T--------------------------------------------------------------------------YGRRGRGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGKN--------GDNCNYDGY--------ANSMYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------K-GQM-PFYA-------------------------------------------------------------------EECSSLF------------------------AVTFS-S-------------GS-----------------R---------------------------P-QRNI------------------------------------------------------------------LT--------------------------------------------------------------------------------------------------------------------------------TDWTLGPGTG--CT--NTHTG------TSAAAPLAA----G---------------------------M------------------ISLM----LE------------AKPCL----------------------------------------------------------------------------------SW------------------RDVQHII-------VYSALKID--QK-K-------------------------GEWT--------------------------------------------VNAAGFHHS----------------------------------------- 906
 907 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGQ--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----M--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GHM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATQYE--DR-R-------------------------AEWV--------------------------------------------TNEAGFSHS----------------------------------------- 907
 908 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------V-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----EENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----M--------------------------------------------------------------------------AGRQGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATQYE--DH-R-------------------------ADWL--------------------------------------------TNEAGFSHS----------------------------------------- 908
 909 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------V-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----EENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----M--------------------------------------------------------------------------AGRQGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTAIQYE--DH-H-------------------------ADWL--------------------------------------------TNEAGFSHS----------------------------------------- 909
 910 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRQGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATRYE--DR-R-------------------------AEWV--------------------------------------------TNEAGFSHS----------------------------------------- 910
 911 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATQYE--DR-R-------------------------ADWV--------------------------------------------TNEAGFSHS----------------------------------------- 911
 912 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRQGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATRYE--DR-R-------------------------AEWV--------------------------------------------TNEAGFSHS----------------------------------------- 912
 913 ----------------------D----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----LENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AFG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRQGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTA------------------------------------------------------------------------------------------------------------------------------------- 913
 914 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VFTATQYE--DR-R-------------------------ADWV--------------------------------------------TNEAGFSHS----------------------------------------- 914
 915 -------------LNNRRSPGRD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------Q---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----VENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------VA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------E-GRM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VFTATQYE--DR-R-------------------------ADWV--------------------------------------------TNEAGFSHS----------------------------------------- 915
 916 -------------LNNRKSPGKD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------K---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----EENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCT---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------IA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------M-GSM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-MRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATKYE--------------------------------------------------------------------------------------------------------------------------------- 916
 917 -------------LNNRKSPGKD----IN-----------VTGVW-------ERN-VTGR--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GVEH-T------I-------------K---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----EENGN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVPNN--------------------------------------------------------------SFCT---VGV--AYG-S----------RI-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------IA--FNK--------------------------------------------HYQINDI-----------------------------------------YSCSWGPDD----D-GK--------------------------------------------------------------TVDGPH-QLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRRGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQH--------NDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------M-GSM-PFYA-------------------------------------------------------------------EECASML------------------------AVTFS-G-------------GD-----------------K---------------------------M-MRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDWDLQKGTG--CT--EGHTG------TSAAAPLAA----G---------------------------M------------------IALM----LQ------------VRPCL----------------------------------------------------------------------------------TW------------------RDVQHII-------VFTATKYE--DR-H-------------------------AKWD--------------------------------------------VNRAGFSHS----------------------------------------- 917
 918 -------------LHNDMKRGMD----IN-----------VTGVW-------ERN-ITGA--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GIQH-N------L-------------A---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----GPSDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVSNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RV-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------IA--FNK--------------------------------------------HYQVNDI-----------------------------------------YSCSWGPDD----D-GR--------------------------------------------------------------TVDGPH-PLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRKGFGSIF--I----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQN--------QDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------S-GRK-PTYA-------------------------------------------------------------------EECASML------------------------AVTFS-S-------------GN-----------------T---------------------------P-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------SDWSLQSGTG--CT--SGHTG------TSAAAPLAA----G---------------------------M------------------VALM----LQ------------VRPCL----------------------------------------------------------------------------------SW------------------RDVQHII-------TYTATQH---DL-Q-------------------------ADWV--------------------------------------------TNGAGFHHS----------------------------------------- 918
 919 -------------LHNDMKRGMD----IN-----------VTGVW-------ERN-ITGA--------------------------G-V--TV--------------V--------------------VVD---------------------------D--------------GIQH-N------L-------------A---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QPNY----------S--------------------------PEGSYDLN-------S-ND--------------PDPMPHP-D----GPSDN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEIA----AVSNN--------------------------------------------------------------SFCA---VGV--AYG-S----------RV-----------------A--G--I--RVL-DGP---LTD-------------------------------------S--------MEA--------------------------IA--FNK--------------------------------------------HYQVNDI-----------------------------------------YSCSWGPDD----D-GR--------------------------------------------------------------TVDGPH-PLGKA-ALQH----GV-----I--------------------------------------------------------------------------AGRKGFGSIF--I----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQN--------QDNCNYDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------S-GRK-PSYA-------------------------------------------------------------------EECASML------------------------AVTFS-S-------------GN-----------------T---------------------------P-LRSI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------SDWSLQSGTG--CT--SGHTG------TSAAAPLAA----G---------------------------M------------------VALM----LQ------------VRPCL----------------------------------------------------------------------------------SW------------------RDVQHII-------TYTATQH---DL-Q-------------------------ADWV--------------------------------------------TNGAGFHHS----------------------------------------- 919
 920 ---------------HNKQGGQD----CN-----------VTGVW-------ANN-ITGR--------------------------G-V--VV--------------A--------------------VVD---------------------------D--------------GVQW-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY----------C--------------------------PEGSFDLN-------S-DD--------------DDPSPEP-D----KDDEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----AVV-N--------------------------------------------------------------DVCG---VGI--AYQ-A----------RF-----------------S--G--I--RIL-DGP---MTD-------------------------------------S--------IEA--------------------------TA--FNK--------------------------------------------HMDVNDV-----------------------------------------YSCSWGPED----D-GK--------------------------------------------------------------TVDGPR-SLAQI-ALKH----GV-----L--------------------------------------------------------------------------AGREGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GASK--------GDNCNYDGY--------ANSIYT---IT---IA--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------F-GYT-PSYA-------------------------------------------------------------------EECTSML------------------------ASTVS-S-------------GN-----------------G---------------------------R-SRSI------------------------------------------------------------------CT--------------------------------------------------------------------------------------------------------------------------------TDWTMGHNSKDRCT--YEHTG------TSAATPLVA----G---------------------------M------------------VALM----LE------------ARPCL----------------------------------------------------------------------------------SW------------------RDVQHIF-------AMTAIPLD--KN-K-------------------------SKWE--------------------------------------------KNSAGYTHSN---------------------------------------- 920
 921 --------------------GQD----CN-----------VTGVW-------ANN-ITGR--------------------------G-V--VV--------------A--------------------VVD---------------------------D--------------GVQW-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY----------C--------------------------PEGSFDLN-------S-DD--------------DDPSPEP-D----KDDEN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TR-C-----------------------AGEIA----AVV-N--------------------------------------------------------------DVCG---VGI--AYQ-A----------RF-----------------S--G--I--RIL-DGP---MTD-------------------------------------S--------IEA--------------------------TA--FNK--------------------------------------------HMDVNDV-----------------------------------------YSCSWGPED----D-GK--------------------------------------------------------------TVDGPR-SLAQI-ALKH----GV-----L--------------------------------------------------------------------------AGREGFGSIF--V----------------VASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GASK--------GDNCNYDGY--------ANSIYT---IT---IA--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------F-GYT-PSYA-------------------------------------------------------------------EECTSML------------------------ASTVS-S-------------GN-----------------G---------------------------R-SRSI------------------------------------------------------------------CT--------------------------------------------------------------------------------------------------------------------------------TDWTMGHNSKDRCT--YEHTG------TSAATPLVA----G---------------------------M------------------VALM----LE------------ARPCL----------------------------------------------------------------------------------SW------------------RDVQHIF-------AMTAIPLD--KN-K-------------------------SKWE--------------------------------------------KNSAGYTHS----------------------------------------- 921
 922 ----------------------D----IN-----------VTEVW-------LSN-ITGV--------------------------G-V--TV--------------A--------------------VVD---------------------------D--------------GLQH-G------N-------------Q---------E--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SDNY----------N--------------------------AKGSYDFN-------D-YD--------------YDPNPDT------SSVSN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGLVA----SVANN--------------------------------------------------------------SICG---VGV--AYK-S----------SV-----------------S--G--I--RLL-DGV---ITD-------------------------------------L--------LEA--------------------------KA--LTY--------------------------------------------KTHINHI-----------------------------------------YSCSWGPTD----D-GM--------------------------------------------------------------TVEAPG-TLAQL-AFQL----GT-----Q--------------------------------------------------------------------------RGRYGYGSIF--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNK--------QDNCNFDGY--------ANSIYT---VT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--E--------L-DKK-PYYA-------------------------------------------------------------------EECSSKL------------------------AVTYS-N-------------GV-----------------K---------------------------RGDRNI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------ADITKGHS----CT--SGFSG------TSAAAPMAA----G---------------------------L------------------IALA----LQ------------VRDCL----------------------------------------------------------------------------------TW------------------RDVQGII-------VYSAVPID--IS-E-------------------------GDWF--------------------------------------------TNGADFMHSHQHGFGVLD-------------------------------- 922
 923 -------------LHNLRDPNHD----IN-----------VTNVW-------NHN-ITGK--------------------------D-V--VV--------------A--------------------IID---------------------------D--------------GVQW-K------N-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VDNY--------VCSVALHFLRSSYNCSLARTTCSQNYEAEPKGSWDVI-------D-ND--------------DDPVPAF-A----YPQTN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TR-C-----------------------AGVAS----AVT-N--------------------------------------------------------------QYCG---VGV--AYG-S----------KF-----------------S--A--I--RLL-DTT---TTD-------------------------------------A--------KES--------------------------AA--FST--------------------------------------------KSQTNDI-----------------------------------------YSCSWGPLD----D-GK--------------------------------------------------------------TVDGPR-ELTKK-AILA----GV-----T--------------------------------------------------------------------------NGRKKLGNIF--V----------------VAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTL---------DDCNYDGF--------ANSVYT---LT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--E--------N-LSP-TPYS-------------------------------------------------------------------EPCSAMH------------------------AVAFGGS-------------SG-----------------S---------------------------A---SI------------------------------------------------------------------TT--------------------------------------------------------------------------------------------------------------------------------TDWKSDRNSG--CT--RSFTG------TSAAAPMAA----G---------------------------I------------------VALM----LS------------TNFCL----------------------------------------------------------------------------------TW------------------RDVQYII-------ALSSVKIR--AN-D-------------------------NRWM--------------------------------------------TNTAGFHH------------------------------------------ 923
 924 ---------------------------LN-----------VTPVW-------RKG-LTGR--------------------------G-V--AI--------------A--------------------VLD---------------------------D--------------NVNP-S------N-------------P---------E--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RRNY----------D--------------------------PNISVDLG---------AK--------------TGPGIKK---------NP----------------------------------------------------------------------------------------------------------------------------------------------------------------------------IHG-------TY-C-----------------------ASIIA----AEANN--------------------------------------------------------------NFCG---VGV--AFN-A----------RV-----------------G--G--V--RLLAKKR---VLD-------------------------------------V--------QEA--------------------------RA--LNY--------------------------------------------KLHEVDI-----------------------------------------YSASWGPPD----D-GK--------------------------------------------------------------HIGGPG-KLSYH-ALER----GV-----E--------------------------------------------------------------------------LGRRGRGAIY--I----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGIK--------GDNCAYDSY--------ASSVYT---LS---VS--A------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--P--------Q-GLS-PYYA-------------------------------------------------------------------EPCPAVL------------------------TSLYV-G-------------GQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HLRPKSPFDAEKT--DNFQG------TSAAAPLAA----G---------------------------I------------------IALL----LE------------ANPLL----------------------------------------------------------------------------------TW------------------RDVQHLV-------VLSS------------------------------------------------------------------------------------------------------------------------------------- 924
 925 --------------------GMD----LN-----------VMPAW-------KLG-YTGK--------------------------G-I--VA--------------T--------------------IVD---------------------------D----------------DS-F------C-------------C---------Y--------------------------------R-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKTT----------D--------------------------LNASYDYN-------NLTNPYSPHPGVNDGDQDPHPNDSP---TLEG--EN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHG-------TK-C-----------------------GGEVG----AEANN--------------------------------------------------------------GICG---VGV--AYG-V----------SL-----------------G--G--I--RVL-DGP---ITD-------------------------------------A--------IEA--------------------------AA--LSH--------------------------------------------ASDYIDI-----------------------------------------YNCCWGPMD----D-GE--------------------------------------------------------------TFEGPG-EEGFQ-ALKN----GV-----E--------------------------------------------------------------------------NGRDGKGSIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLT--------DDDCAADGY--------VSSIYT---IG---IG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--G--------Q-GHS-AFFI-------------------------------------------------------------------ESCSPVM------------------------AVTLV-G-------------ATH-----NAPEGVMLESDD---------------------------NW---V------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TSLNHQ------CT--EHFTG------TSSAAPFAT----G---------------------------S------------------IAVV----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQHIV-------V---------------------------------------------------------------------------------------------------------------------------------------- 925
 926 --------------------GLD----IN-----------VIPAW-------VNG-YTGK--------------------------G-I--VA--------------T--------------------IVD---------------------------D--------------GLDY-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KRNY----------D--------------------------PEASFDYS-------DPSN------------LNGNPMPVA---TARD--QM----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGEVA----MEANN--------------------------------------------------------------GNCG---VGV--AYE-A----------KV-----------------G--G--I--RLI-TGP---TSD-------------------------------------A--------QEA--------------------------AS--LSH--------------------------------------------KRDHIDV-----------------------------------------YSCCWGPPD----S-GR--------------------------------------------------------------KVQKPG-ELVTR-ILED----ST-----T--------------------------------------------------------------------------NGRNGRGNVY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHK--------DDDCGADGY--------VSSIYT---LA---VG--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--V--------D-GLS-AYYS-------------------------------------------------------------------ESCSPTM------------------------AVVPT-G-------------GQHRLDNFNGDLADMIKRGE---------------------------VYEQNV------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TDQGHR------CT--DRFQG------TSSAAPLAT----G---------------------------I------------------VALT----LQ------------ANPDL----------------------------------------------------------------------------------TW------------------RDVQHIV-------VRGA------------------------------------------------------------------------------------------------------------------------------------- 926
 927 -------------LFNPDEPGHD----MN-----------ITGVW-------IEG-ISGK--------------------------G-I--TI--------------G--------------------FID---------------------------D--------------GLDY-E------N-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNY-------------------------------------AKGSYDFN-------F-HK--------------LDPMP--------TLMDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TR-C-----------------------AGEVA----AVK-N--------------------------------------------------------------NVCG---IGV--AWS-S----------KV-----------------S--G--L--RVL-SGR---LTN-------------------------------------T--------DEA--------------------------AA--INY--------------------------------------------AFNTTQI-----------------------------------------YSCSWGPRD----D-GK--------------------------------------------------------------TMEAPP-QIVTR-AVKN----GI-----D--------------------------------------------------------------------------NGRNGLGSLF--V----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGAR--------GDNCNFDGY--------TNSIYT---IT---VA--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--R--------Y-EGH-PSFS-------------------------------------------------------------------EQCPANM------------------------ISMWSGQ-------------GG-----------------F---------------------------S---GI------------------------------------------------------------------IT--------------------------------------------------------------------------------------------------------------------------------TD----WKTG--CT--DRHGG------TSAAAPLAA----G---------------------------I------------------YSLV----LS------------IRPDL----------------------------------------------------------------------------------TW------------------RDVQRLT-------LETAIPVN--LQ-D-------------------------SDWL--------------------------------------------NTAAGRLYN----------------------------------------- 927
 928 --------------------GHD----LN-----------VTGVW-------LEG-ITGK--------------------------G-A--TA--------------A--------------------IVD---------------------------D--------------GLDM-Y------S-------------N---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SPNY----------F--------------------------PEGSWDFN-------D-HT--------------AEPRP--------RLRDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHG-------TR-C-----------------------AGEDA----AAR-N--------------------------------------------------------------DVCR---VGV--AYD-S----------QI-----------------A--G--I--RILFRTY---LTH-------------------------------------P--------TKP--------------------------SA--INY--------------------------------------------AHQENDI-----------------------------------------YSCSWGPPD----D-GA--------------------------------------------------------------TMDAPG-ILVSR-AIVN----GV-----Q--------------------------------------------------------------------------KGRDGKGSIF--V----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GPAS--------GDNCNFDGY--------TNSIYS---IT---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--R--------E-GQH-PQYS-------------------------------------------------------------------ESCSAQL------------------------VVAYS-S-------------GI-----------------S---------------------------D---AI------------------------------------------------------------------ST--------------------------------------------------------------------------------------------------------------------------------TD---VGTDR--CY--SVHGG------TSAAGPLVV----G---------------------------A------------------ISLA----LS------------VRPEL----------------------------------------------------------------------------------TW------------------RDAQYIV-------LETAVPVH--ED-D-------------------------GSWQ--------------------------------------------VTKSGRK------------------------------------------- 928
 929 ---------------------------MN-----------VVPVW-------DMG-ITGK--------------------------G-V--IS--------------S--------------------LVD---------------------------D--------------GLDY-D------S-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AENF----------D--------------------------RENSYDFN-------D-HE--------------ELPTP--------KNYDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TR-C-----------------------AGQVA----AVR-N--------------------------------------------------------------NACG---VGI--AYN-S----------KV-----------------A--G--V--RIL-SGP---ISD-------------------------------------V--------DEA--------------------------AA--LNY--------------------------------------------GFHNVSI-----------------------------------------YSCSWGPPD----K-GQ--------------------------------------------------------------SMEGPG-YLIKK-AVVN----GI-----N--------------------------------------------------------------------------NGRGGKGSIF--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAGF--------GDQCNFDGY--------TNSIYS---VT---VS--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--Y--------K-GMH-PYYS-------------------------------------------------------------------ESCAANM------------------------IAAYS-S-------------GS-----------------G---------------------------K---HI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TDKNSRGKTQ--CS--RVHGG------TSAAAPNAV----G---------------------------V------------------FALA----LE------------VRPDL----------------------------------------------------------------------------------TW------------------RDIQHLC-------VETARMIN--KE-D-------------------------PDWD--------------------------------------------YIANDKRY------------------------------------------ 929
 930 ---------------------------MN-----------VTPVW-------DMG-YTGK--------------------------G-V--IT--------------S--------------------ILD---------------------------D--------------GLDY-T------S-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------D--------------------------PDNSYDFN-------D-HE--------------ALPYP--------KRVRD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGQIA----AGK-N--------------------------------------------------------------KACG---VGI--AYE-S----------KV-----------------A--G--V--RIL-SGR---ITT-------------------------------------V--------DEA--------------------------AA--INY--------------------------------------------GFQNVSI-----------------------------------------YSCSWGPRD----D-GT--------------------------------------------------------------KMQTPP-YIVRK-AVLN----GI-----N--------------------------------------------------------------------------KGRGGKGSIF--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAHK--------GDQCNFDGY--------TNSIYS---VT---VG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--F--------R-GQH-PKYS-------------------------------------------------------------------EACAANM------------------------VVAYS-S-------------GS-----------------G---------------------------Q---HI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TD---RGKDE--CA--LVHGG------TSAAAPNVA----G---------------------------V------------------FALA----LQ------------ARPDL----------------------------------------------------------------------------------TW------------------RDIQYLC-------VETARQIN--PK-D-------------------------RDWE--------------------------------------------RTATGRYY------------------------------------------ 930
 931 ---------------------------MN-----------VTPVW-------DMG-YTGK--------------------------G-I--LT--------------A--------------------LID---------------------------D--------------GLDY-T------A-------------A---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AEKF----------D--------------------------AENSYDFN-------D-HV--------------PLPYP--------KLEWQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------HHG-------TR-C-----------------------AGQIA----ASK-N--------------------------------------------------------------NVCG---VGI--AYD-S----------RV-----------------S--G--L--RIL-GGR---ITT-------------------------------------V--------DQA--------------------------TA--LNY--------------------------------------------GFQNVHI-----------------------------------------YSCSWGPRD----D-GT--------------------------------------------------------------KMQAPR-YIVRK-AFLN----GV-----N--------------------------------------------------------------------------KGRGGKGSIY--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRS--------GDQCNFDGY--------TNSIYS---VT---VG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--Y--------K-GLH-PTYS-------------------------------------------------------------------ETCTANM------------------------IVAYS-S-------------GS-----------------G---------------------------E---HI------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TD---RGQNE--CA--FSHGG------TSAAAPNAA----G---------------------------V------------------IALA----LQ------------ARPEL----------------------------------------------------------------------------------TW------------------RDVQHLC-------VETA------------------------------------------------------------------------------------------------------------------------------------- 931
 932 ----------------------E----LN-----------VTGLW-------GRG-ITGE--------------------------G-V--HV--------------V--------------------IID---------------------------D--------------GLDV-E------S-------------K---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------F--------------------------AEGSYDFN-------D-HT--------------ELPIP--------RLKDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------TR-C-----------------------AGEIA----AVP-N--------------------------------------------------------------DVCG---VGV--AYD-S----------KI-----------------A--G--V--RIL-SAP---ISD-------------------------------------A--------DEA--------------------------AA--LNY--------------------------------------------AYQLNDI-----------------------------------------YSCSWGPPD----D-GR--------------------------------------------------------------SMEAPD-GLILK-AMVN----GV-----Q--------------------------------------------------------------------------KGRDGKGSVF--V----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGS--------DDQCNFDGY--------TNSIFS---VT---VG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--R--------K-GLH-PYYS-------------------------------------------------------------------EMCAAMM------------------------VVAPS-S-------------GS-----------------G---------------------------D---HI------------------------------------------------------------------HT--------------------------------------------------------------------------------------------------------------------------------TD---VGKDK--CS--HSHGG------TSAAAPLAV----G---------------------------V------------------FALA----LS------------VRPDL----------------------------------------------------------------------------------TW------------------RDIQHLA-------VRHAVFFN--PD-D-------------------------PAWE--------------------------------------------LTAAGRHF------------------------------------------ 932
 933 --------------------------------------------W-------GRG-VTGE--------------------------G-V--HV--------------V--------------------IID---------------------------D--------------GLDV-E------S-------------K---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------F--------------------------AEGSYDFN-------D-HT--------------ALPIP--------RLRDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------TR-C-----------------------AGEIA----AVP-N--------------------------------------------------------------DVCG---VGV--AYG-S----------KI-----------------A--G--V--RIL-SAP---ISD-------------------------------------A--------DEA--------------------------AA--LNY--------------------------------------------AYQLNDI-----------------------------------------YSCSWGPPD----D-GR--------------------------------------------------------------SMEAPD-GLILK-AMVN----GV-----Q--------------------------------------------------------------------------KGRDGKGSVF--V----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGS--------DDQCNFDGY--------TNSIFS---VT---VG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--R--------K-GLH-PYYS-------------------------------------------------------------------EMCAAMM------------------------VVAPS-S-------------GS-----------------G---------------------------D---HI------------------------------------------------------------------HT--------------------------------------------------------------------------------------------------------------------------------TD---VGKDK--CA--HNHGG------TSAAAPLAV----G---------------------------V------------------FALA----LS------------VRPDL----------------------------------------------------------------------------------TW------------------RDIQHLA-------VRHAVFFN--PD-D-------------------------PAWE--------------------------------------------LTAAGRNFSYKYGYGKLDAGLF---------------------------- 933
 934 -------------LINQKNPGND----IN-----------VTGVW-------KQG-IAGK--------------------------G-V--TV--------------V--------------------ILD---------------------------D--------------GLDF-N------S-------------T---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADNF----------Y--------------------------AEGSYDFN-------D-HE--------------PLPKP--------KLWDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TR-C-----------------------AGQIA----AVK-N--------------------------------------------------------------NACG---VGI--AYE-S----------KV-----------------A--G--I--RIL-SGD---LTD-------------------------------------A--------DEA--------------------------LA--LNY--------------------------------------------DYQHNHI-----------------------------------------FSCSWGPPD----N-GE--------------------------------------------------------------NMEAPK-AILTD-AIAN----GV-----R--------------------------------------------------------------------------NGRDGKGSIY--V----------------FATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GATL--------GDNCNFDAY--------TNSIYT---IT---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--H--------T-NKH-PAYS-------------------------------------------------------------------ESCSAQL------------------------VVTYS-S-------------GS-----------------G---------------------------E---YI------------------------------------------------------------------QT--------------------------------------------------------------------------------------------------------------------------------TD---VGRQD--CF--DRHGG------TS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------- 934
 935 -------------LINQMNTGND----IN-----------VTGVW-------KQG-ISGK--------------------------G-V--TV--------------V--------------------IVD---------------------------D--------------GLDY-N------S-------------T---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AANF----------Y--------------------------AEGSYDFN-------D-HE--------------SLPTP--------KLWDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TR-C-----------------------AGQIA----AVR-N--------------------------------------------------------------NACG---IGI--AYE-S----------KI-----------------A--G--V--RIL-SGD---LTD-------------------------------------A--------DEA--------------------------LA--LNY--------------------------------------------KYQENDI-----------------------------------------FSCSWGPTD----N-GE--------------------------------------------------------------TMEAPK-GILAD-AFLN----GI-----K--------------------------------------------------------------------------NGRGGKGSIY--V----------------FATG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTS--------GDNCNFDGY--------TNSIYT---IT---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--F--------T-NSH-PPYS-------------------------------------------------------------------EACSAQL------------------------V------------------------------------------------------------------------------------------------------------------------------------------QT--------------------------------------------------------------------------------------------------------------------------------TD---VGKND--CS--DRHGG------TSAAAPNAA----G---------------------------I------------------FALV----LS------------VRPDL----------------------------------------------------------------------------------SW------------------RDLQHLC-------VQTAVPIK--TE-D-------------------------SDWK--------------------------------------------RLPSGRIY------------------------------------------ 935
 936 -------------IFNSNNPGHD----LN-----------LREVW-------DAG-YFGE--------------------------N-V--TV--------------A--------------------FVD---------------------------D--------------GIDF-K------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QAAY----------T--------------------------SLGSWDFN-------D-NI--------------ADPLP--------KLSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------TR-C-----------------------AGEVA----AAW-N--------------------------------------------------------------DVCG---VGI--APR-A----------KV-----------------A--G--L--RIL-SAP---ITD-------------------------------------A--------VES--------------------------EA--LNY--------------------------------------------GFQTNHI-----------------------------------------YSCSWGPAD----D-GR--------------------------------------------------------------AMDAPN-TATRR-ALMN----GV-----L--------------------------------------------------------------------------NGRNGLGSIF--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGHY--------HDNCNFDGY--------TNSIFS---AT---IG--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--A--------E-HKI-PFYS-------------------------------------------------------------------EVCAAQL------------------------VSAYS-S-------------GS-----------------H---------------------------L---SI------------------------------------------------------------------LT--------------------------------------------------------------------------------------------------------------------------------TN----PEGT--CT--RSHGG------TSAAAPLAS----A---------------------------V------------------YALA----LS------------IRPDL----------------------------------------------------------------------------------SW------------------RDIQHIT-------VYSASPFDSPSQ-N-------------------------AEWQ--------------------------------------------KTPAGFQFS----------------------------------------- 936
 937 -------------LLNTRYPKND----MN-----------VTGLW-------QKN-ITGH--------------------------G-I--VV--------------A--------------------VVD---------------------------D--------------GLDY-E------S-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------C--------------------------AEGSWDFN-------S-NT--------------ALPKP--------MLSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TR-C-----------------------AGEIA----AAK-N--------------------------------------------------------------QFCG---LGV--AFN-S----------KV-----------------S--G--I--RIL-SED---ITP-------------------------------------E--------DEA--------------------------AS--LVY--------------------------------------------GLDINDI-----------------------------------------YSCSWGPTD----N-GE--------------------------------------------------------------ELQAPS-DLVKK-AIIR----GV-----T--------------------------------------------------------------------------EGRDRKGALY--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGAL--------GDNCNYDGY--------TNSIYS---IT---VS--A------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--H--------R-GLH-PTYA-------------------------------------------------------------------ESCSAVL------------------------VVAHS-S-------------GS-----------------G---------------------------N---FI------------------------------------------------------------------RT--------------------------------------------------------------------------------------------------------------------------------TD---VNGQ---CF--DHHGG------TSAAAPLAA----G---------------------------V------------------YALL----LQ------------VNPNL----------------------------------------------------------------------------------TW------------------RDVQYLT-------ILTSIEVN--PD-D-------------------------SDWQ--------------------------------------------EGSLGRRYS----------------------------------------- 937
 938 -------------LVNPSFPGSD----IN-----------VLDLW-------YNN-ITGA--------------------------G-V--VA--------------A--------------------IVD---------------------------D--------------GLDY-E------N-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------C--------------------------AEGSWDFN-------D-NT--------------NLPKP--------RLSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TR-C-----------------------AGEIA----AKKGN--------------------------------------------------------------NFCG---VGV--GYN-A----------KI-----------------S--G--I--RIL-SGD---ITT-------------------------------------E--------DEA--------------------------AS--LIY--------------------------------------------GLDVNDI-----------------------------------------YSCSWGPAD----D-GR--------------------------------------------------------------HLQGPS-DLVKK-ALVK----GV-----T--------------------------------------------------------------------------EGRDSKGAIY--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTR--------GDNCNYDGY--------TNSIYS---IT---IG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--H--------K-DLH-PPYS-------------------------------------------------------------------EGCSAVM------------------------AVTYS-S-------------GS-----------------G---------------------------E---YI------------------------------------------------------------------HS--------------------------------------------------------------------------------------------------------------------------------SD---INGR---CS--NSHGG------TSAAAPLAA----G---------------------------V------------------YTLL----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQYLS-------ILSAVGLE--KNAD-------------------------GDWR--------------------------------------------DSAMGKKYS----------------------------------------- 938
 939 LSINDPLFERQWHLVNPSFPGSD----IN-----------VLDLW-------YNN-ITGA--------------------------G-V--VA--------------A--------------------IVD---------------------------D--------------GLDY-E------N-------------E---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDNF----------C--------------------------AEGSWDFN-------D-NT--------------NLPKP--------RLSDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TR-C-----------------------AGEIA----AKKGN--------------------------------------------------------------NFCG---VGV--GYN-A----------KI-----------------S--G--I--RIL-SGD---ITT-------------------------------------E--------DEA--------------------------AS--LIY--------------------------------------------GLDVNDI-----------------------------------------YSCSWGPAD----D-GR--------------------------------------------------------------HLQGPS-DLVKK-ALVK----GV-----T--------------------------------------------------------------------------EGRDSKGAIY--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTR--------GDNCNYDGY--------TNSIYS---IT---IG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--H--------K-DLH-PPYS-------------------------------------------------------------------EGCSAVM------------------------AVTYS-S-------------GS-----------------G---------------------------E---YI------------------------------------------------------------------HS--------------------------------------------------------------------------------------------------------------------------------SD---INGR---CS--NSHGG------TSAAAPLAA----G---------------------------V------------------YTLL----LE------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQYLS-------ILSAVGLE--KNAD-------------------------GDWR--------------------------------------------DSAMGKKYSHRYGFGKIDAHKLIEMSKTWENVNAQTWFYLPTLYVSQSTN 939
 940 --------------------GHD----VN-----------VTGLW-------LEN-ILGQ--------------------------G-I--VT--------------A--------------------LVD---------------------------D--------------GVDA-E------S-------------D---------D--------------------------------I-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQNF----------N--------------------------SEGSWDFN-------N-KG--------------KSPLP--------RLFDD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TR-C-----------------------AGEIA----AVK-N--------------------------------------------------------------DVCG---IGV--AWK-S----------QV-----------------S--G--I--RIL-SGP---ITS-------------------------------------S--------DEA--------------------------EA--MVY--------------------------------------------GLDTNDI-----------------------------------------YSCSWGPTD----N-GK--------------------------------------------------------------VLSEPD-VIVKK-AMIK----GI-----Q--------------------------------------------------------------------------EGRDKKGAIY--V----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGRF--------GDSCNFDGY--------TNSIYS---IT---VG--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--Y--------K-GLH-PQYS-------------------------------------------------------------------EACSAVM------------------------VVTYS-S-------------GS-----------------G---------------------------E---HI------------------------------------------------------------------HT--------------------------------------------------------------------------------------------------------------------------------TD---IKKK---CS--ATHGG------TSAAAPLAS----G---------------------------I------------------YSLI----LS------------ANPNL----------------------------------------------------------------------------------TW------------------RDVQYIS-------VLSATPIN--EE-D-------------------------G------------------------------------------------------------------------------------------------- 940
 941 -------------LFNTKDPGVD----IN-----------VTGLW-------LEG-IRGK--------------------------G-V--TV--------------A--------------------IVD---------------------------N--------------GIDY-T------N-------------L---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------APNF----------N--------------------------AEASLNFA-------T-GT--------------TDVKPEY--------KYN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TR-S-----------------------AGEVA----AAR-N--------------------------------------------------------------DFCG---IGV--AYE-S----------NI-----------------S--G--L--RYI-PSA---HSS-------------------------------------W--------NEG--------------------------DA--LIY--------------------------------------------KYDVNHI-----------------------------------------YSCSWGPAD----T-GN--------------------------------------------------------------LIQDIS-YTSYS-AIIK----GI-----N--------------------------------------------------------------------------EGKNGLGSIY--V----------------FGSG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-Y--------FDDCNYDGY--------ANSPYT---IT---IA--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--A--------K-EER-FMFS-------------------------------------------------------------------EPCPCIL------------------------ASTYS----------------------------------G---------------------------RRGAYI------------------------------------------------------------------YT--------------------------------------------------------------------------------------------------------------------------------TDVGTTE-----CT--FLHTG------TSASTPLAA----G---------------------------V------------------IALL----LS------------ACPNL----------------------------------------------------------------------------------TW------------------RDVQALI-------VETAVPFNPSHP----------------------------DWD--------------------------------------------DLPSGRRYN----------------------------------------- 941
 942 ----------------------D----LN-----------AEPAW-------IQG-YTGN--------------------------G-I--LV--------------G--------------------VVD---------------------------D--------------GVQH-T------H-------------N---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RNNY-------------------------------------VS-TYSYD-------F-ND--------------NDRNP-S-PVGT-DS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TA-C-----------------------AGEIV----MRRDN--------------------------------------------------------------NVCG---VGV--AYD-A----------SM-----------------A--G--L--RLL-GRR---TTD-------------------------------------S--------TDA--------------------------SA--LSY--------------------------------------------SRNNIDI-----------------------------------------YSNSWGPPD----T-SV--------------------------------------------------------------LVDGPKYLLIIV-AFNI----GT-----S--------------------------------------------------------------------------LGRNGLGSIY--V----------------FSSG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQY--------DDSCAADGY--------ASNRYT---IG---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--Q--------A-GRQ-AFYD-------------------------------------------------------------------EDCSGKM------------------------AVTYS-Y-------------NS----------------AV----------------------------TSDQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TYPNSG------CV--KSFTG------TSASAPLMT----G---------------------------V------------------ILLA----LE------------VNPNL----------------------------------------------------------------------------------SW------------------RDVQYL------------------------------------------------------------------------------------------------------------------------------------------------- 942
 943 -----------------------------------------------------EG-ITGH--------------------------N-S--TA--------------L--------------------VID---------------------------N--------------GIQL-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HSNI----------N--------------------------VSLCYSTL-------T-HS--------------TDINPQS-SLKE-DN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TS-C-----------------------AGEIA----MIHDN--------------------------------------------------------------GICG---AGV--AYG-A----------TI-----------------A--G--Y--QVD-FSE---LLP-------------------------------------S--------EEV--------------------------DA--FHH--------------------------------------------FNDEIQV-----------------------------------------YSNSWGPED----N-GF--------------------------------------------------------------TVQGPQ-TLAQE-ALQF----GV-----E--------------------------------------------------------------------------SGRNGLGSIY--V----------------FSSG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGQY--------DDSCAADGY--------ASNRYT---IG---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--Q--------A-GRQ-AFYD-------------------------------------------------------------------EDCSGKM------------------------AVTYS-Y-------------NS----------------AV----------------------------TSDQV------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------TYPNSG------CV--KSFTG------TSASAPLMT----G---------------------------V------------------ILLA----LE------------VNPNL----------------------------------------------------------------------------------SW------------------RDVQYLI-------AYTSKSSPLVDG-N---------------------------FV--------------------------------------------TNGAGLRVSSKFGFGAIDAEAL---------------------------- 943
 944 ----------------------N----MR-----------VLEAW-------IQG-FTGE--------------------------G-V--TV--------------G--------------------VVD---------------------------D--------------GLQR-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SANY----------D--------------------------DNSSYDFV-------N-YD--------------SDPSPYY-QFPYFDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TE-C-----------------------AGVVS----MSKSN--------------------------------------------------------------GLCG---VGV--AYN-A----------KV-----------------A--G--L--RIF-SSSHKGTTD-------------------------------------S--------QEA--------------------------NA--LNY--------------------------------------------RYQNIDI-----------------------------------------YSNSWGPVD----N-GF--------------------------------------------------------------TVDGPK-LLTRL-ALQI----GA-----A--------------------------------------------------------------------------KGRQNKGSIF--V----------------WAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSK--------HDSCATDGY--------VNSIYT---IA---VG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--S--------Q-GIP-SSFD-------------------------------------------------------------------ERCSAKM------------------------AVAFS-F-------------NA----------------GT---------------------------DEASHN------------------------------------------------------------------PT--------------------------------------------------------------------------------------------------------------------------------TTLTSR------CT--ESFTG------TSAATPLLS----G---------------------------V------------------IALA----LQ------------ANPLL----------------------------------------------------------------------------------TW------------------RDIQYL------------------------------------------------------------------------------------------------------------------------------------------------- 944
 945 ----------------------N----MR-----------VLEAW-------IQG-FTGE--------------------------G-V--TV--------------G--------------------VVD---------------------------D--------------GLQR-T------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SANY----------D--------------------------DNSSYDFV-------N-YD--------------SDPSPYY-QFPYFDS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------TE-C-----------------------AGVVS----MSKSN--------------------------------------------------------------GLCG---VGV--AYN-A----------KV-----------------A--G--L--RIF-SSSHKGTTD-------------------------------------S--------QEA--------------------------NA--LNY--------------------------------------------RYQNIDI-----------------------------------------YSNSWGPVD----N-GF--------------------------------------------------------------TVDGPK-LLTRL-ALQI----GA-----A--------------------------------------------------------------------------KGRQNKGSIF--V----------------WAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGSK--------HDSCATDGY--------VNSIYT---IA---VG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--S--------Q-GIP-SSFD-------------------------------------------------------------------ERCSAKM------------------------AVAFS-F-------------NA----------------GT---------------------------DEASHN------------------------------------------------------------------PT--------------------------------------------------------------------------------------------------------------------------------TTLTSR------CT--ESFTG------TSAATPLLS----G---------------------------V------------------IALA----LQ------------ANPLL----------------------------------------------------------------------------------TW------------------RDIQYLI-------AYTSNSQVLMKE-E-----------------------NARLWM--------------------------------------------TNGAGMSVS----------------------------------------- 945
 946 -------------------PGSD----IN-----------VVPAW-------IEG-VSGE--------------------------N-T--YA--------------L--------------------IID---------------------------N--------------GIQL-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNI----------D--------------------------TSLCYSTI-------T-GS--------------NDILPTR-RLSD-PEYPY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-C-----------------------AGVIA----MIHDN--------------------------------------------------------------DICG---AGV--AYH-A----------TI-----------------G--G--F--QMD-FDR---KTP-------------------------------------S--------DEA--------------------------NA--FNF--------------------------------------------KSQIIQV-----------------------------------------SSNSWGPLD----N-GY--------------------------------------------------------------TVEKPG-YVSNE-ALIE----GV-----T--------------------------------------------------------------------------SGRNGLGTIY--V----------------FSAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNK--------ADSCAADGY--------ASSIYT---IA---IG--S------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--Q--------D-GNS-PTYE-------------------------------------------------------------------EACSAKM------------------------AVAYS----------------N----------------SR----------------------------PGNQV------------------------------------------------------------------VS--------------------------------------------------------------------------------------------------------------------------------TWPESE------CV--RNFTG------TSAATPLVS----G---------------------------V------------------ILLA----LE------------VNPKL----------------------------------------------------------------------------------SW------------------RDIQYLI-------AYTSNSN--IDG-S---------------------------FQ--------------------------------------------DNGGGLRY------------------------------------------ 946
 947 ----------------------D----IN-----------VVPAW-------IEG-VSGE--------------------------N-T--YA--------------L--------------------IID---------------------------N--------------GIQL-N------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QDNI----------D--------------------------TSLCYSTI-------T-GS--------------NDILPTR-RLSD-PEYPY----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TE-C-----------------------AGVIA----MIHDN--------------------------------------------------------------DICG---AGV--AYH-A----------TI-----------------G--G--F--QMD-FDR---KTP-------------------------------------S--------DEA--------------------------NA--FNF--------------------------------------------KSQIIQV-----------------------------------------SSNSWGPLD----N-GY--------------------------------------------------------------TVEKPG-YVSNE-ALIE----GV-----T--------------------------------------------------------------------------SGRNGLGTIY--V----------------FSAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNK--------ADSCAADGY--------ASSIYT---IA---IG--S------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--Q--------D-GNS-PTYE-------------------------------------------------------------------EACSAKM------------------------AVAYS----------------N----------------SR----------------------------PGNQV------------------------------------------------------------------VS--------------------------------------------------------------------------------------------------------------------------------TWPESE------CV--RNFTG------TSAATPLVS----G---------------------------V------------------ILLA----LE------------VNPKL----------------------------------------------------------------------------------SW------------------RDIQYLI-------AYTSNSN--IDG-S---------------------------FQ--------------------------------------------DNGGGLRYDD---------------------------------------- 947
 948 ----------------------D----LN-----------VVHAW-------VQG-VTGE--------------------------G-I--RV--------------S--------------------VVD---------------------------D--------------GVCH-A------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNNY----------D--------------------------SSASFNFV-------E-FT--------------NDPTPP-------NPKKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-C-----------------------AGIIA----MQKDS--------------------------------------------------------------GICG---VGV--AYK-A----------RI-----------------G--G--I--RVN-LSS---SSD-------------------------------------I--------IES--------------------------SA--LGH--------------------------------------------HNNYVDI-----------------------------------------YSNSWGPSD----S-GY--------------------------------------------------------------VVDGPG-ELLTK-TLEN----GV-----L--------------------------------------------------------------------------KGRNGLGNIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNN--------GDSCAADGY--------ASSIYT---IA---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--E--------K-GYQ-ALYD-------------------------------------------------------------------ETCAGKL------------------------AVTYSFN-------------MA----------SYSASSDN---------------------------NMKGQV------------------------------------------------------------------PS--------------------------------------------------------------------------------------------------------------------------------TVSYQQ------CT--VSFMG------SSASAPITA----G---------------------------V------------------IALA----LS------------VNSSL----------------------------------------------------------------------------------TW------------------RDIQYLI-------VYTADHTKLKGA----------------------------NWR--------------------------------------------RNGGGLRVS----------------------------------------- 948
 949 -------------------------------------------AW-------VQG-VTGE--------------------------G-I--RV--------------S--------------------VVD---------------------------D--------------GVCH-A------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNNY----------D--------------------------SSASFNFV-------E-FT--------------NDPTPP-------NPKKQ----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-C-----------------------AGIIA----MQKDS--------------------------------------------------------------GICG---VGV--AYK-A----------RI-----------------G--G--I--RVN-LSS---SSD-------------------------------------I--------IES--------------------------SA--LGH--------------------------------------------HNNYVDI-----------------------------------------YSNSWGPSD----S-GY--------------------------------------------------------------VVDGPG-ELLTK-TLEN----GV-----L--------------------------------------------------------------------------KGRNGLGNIY--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNN--------GDSCAADGY--------ASSIYT---IA---VG--S------------------------------A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--E--------K-GYQ-ALYD-------------------------------------------------------------------ETCAGKL------------------------AVTYSFN-------------MA----------SYSASSDN---------------------------NMKGQV------------------------------------------------------------------PS--------------------------------------------------------------------------------------------------------------------------------TVSYQQ------CT--VSFMG------SSASAPITA----G---------------------------V------------------IALA----LS------------VNSSL----------------------------------------------------------------------------------TW------------------RDIQYLI-------VYTADHTKLKGA----------------------------NWR--------------------------------------------RNGGGLRVSHEFGFGAIDAEAM---------------------------- 949
 950 --------------------GLD----IN-----------LYPIF-------LEN-VTGR--------------------------G-T--NV--------------V--------------------VLD---------------------------D--------------GLDT-S------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QANY----------D--------------------------ETISVNMD-------RPEQ--------------NGLSPRGPRKIIPE--ND----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TR-C-----------------------AGLAG----AVMNN--------------------------------------------------------------SFCS---HGV--APK-T----------KL-----------------G--G--I--RIL-TGP---VTD-------------------------------------F--------VEA--------------------------RG--LSY--------------------------------------------KVELINI-----------------------------------------FCSSWGPSD----D-GI--------------------------------------------------------------TMDLPH-KYTKD-SLSY----GL-----A--------------------------------------------------------------------------KGRNGLGSIY--I----------------FASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGLF--------GDSCGADGF--------VSSPDV---IA---VS--A------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--N--------L-GQK-TMYS-------------------------------------------------------------------EPCSAIR------------------------VSVPV-G-------------GS----------------PE---------------------------LSDMNI------------------------------------------------------------------LP--------------------------------------------------------------------------------------------------------------------------------TTMENDK-----CM--KSFMG------TSAAAPMFA----G---------------------------C------------------LALA----LE------------ANPQL----------------------------------------------------------------------------------TW------------------RDISHLL-------PWSSRIPNPTDK----------------------------GWL--------------------------------------------VNGAGLFYHPYIGYGTID-------------------------------- 950
 951 ----------------------------------------VSEAW-------RYG-FNGS--------------------------G-I--TI--------------A--------------------VLD---------------------------S--------------GIQV-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKNI----------D--------------------------AVNSYDFI-------D-QD--------------SNITP--------D---D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-V-----------------------TGLIA----AEANN--------------------------------------------------------------GVCI---VGV--AYA-S----------TI-----------------I--G--V--RII--G---KTND-------------------------------------I--------TQA--------------------------KA--LSH--------------------------------------------HLSRVDI-----------------------------------------YSNSWGSYD------GF--------------------------------------------------------------LYNRLG-RVSES-ALVD----GV-----T--------------------------------------------------------------------------LGRNGKGVIY--I----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-K--------DDNCNADGK--------LSNLYT---IP---IT--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--I--------D-GKA-APYA-------------------------------------------------------------------EVCASAF------------------------AATYS-S-------------IS-----------------------------------------------ERQL------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------TSLNST------CVSNSNLEG------TSFSAPQAS----A---------------------------I------------------VALA----LQ------------ANPSL----------------------------------------------------------------------------------TW------------------RDVQHLI-------VQTS------------------------------------------------------------------------------------------------------------------------------------- 951
 952 ----------------------------------------VSEAW-------RYG-FNGS--------------------------G-I--TI--------------A--------------------VLD---------------------------S--------------GIQV-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKNI----------D--------------------------AVNSYDFI-------D-QD--------------SNITP--------D---D----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-V-----------------------TGLIA----AEANN--------------------------------------------------------------GVCI---VGV--AYA-S----------TI-----------------I--G--V--RII--G---KTND-------------------------------------I--------TQA--------------------------KA--LSH--------------------------------------------HLSRVDI-----------------------------------------YSNSWGSYD------GF--------------------------------------------------------------LYNRLG-RVSES-ALVD----GV-----T--------------------------------------------------------------------------LGRNGKGVIY--I----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-K--------DDNCNADGK--------LSNLYT---IP---IT--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--I--------D-GKA-APYA-------------------------------------------------------------------EVCASAF------------------------AATYS-S-------------IS-----------------------------------------------ERQL------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------TSLNST------CVSNSNLEG------TSFSAPQAS----A---------------------------I------------------VALA----LQ------------ANPSL----------------------------------------------------------------------------------TW------------------RDVQHLI-------VQTSKRHNIDDDFE------------------------KQPWQ--------------------------------------------INGAGFNVS----------------------------------------- 952
 953 ----------------------------------------VAEAW-------RHG-FNGS--------------------------G-I--TI--------------A--------------------VLD---------------------------N--------------GIQV-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RKNI----------D--------------------------TYHSYDFI-------D-LD--------------SNITP--------DRITD----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TS-V-----------------------TGLIA----AEANN--------------------------------------------------------------DVCI---VGV--AHA-S----------TI-----------------I--G--V--RLI--GPDVPITD-------------------------------------I--------TKA--------------------------KA--LSY--------------------------------------------HLSRVDI-----------------------------------------YSNSWGPQD------KL--------------------------------------------------------------HYHSLG-RVSES-ALVD----GV-----K--------------------------------------------------------------------------LGRNGKGVVY--V----------------FAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-K--------DDNCNADGY--------VSNLYT---IP---IT--S------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G--I--------D-QKA-APYS-------------------------------------------------------------------EVCASAF------------------------SATYS-S-------------IS-----------------------------------------------ERYL------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------TSLNST------CISNSNLQG------TSFSAPQAS----A---------------------------I------------------VALT----LQ------------ANPSL----------------------------------------------------------------------------------TW------------------RDVQHLI-------VQTSKRYNIDDGFE------------------------KQPWQ--------------------------------------------KNGAGFNVS----------------------------------------- 953
 954 ---------------------------MK-----------VKEAW-------SMG-HSGS--------------------------G-V--TV--------------A--------------------VVD---------------------------N--------------GFQL-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RINI----------D--------------------------SANSYDYY-------N-YD--------------PNPSP--------TSVND----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TM-V-----------------------TGLLA----AEANN--------------------------------------------------------------SQCI---VGV--AHQ-S----------TV-----------------I--G--I--KLI--G-DMGVTD-------------------------------------V--------TEA--------------------------LS--LKH--------------------------------------------NLPNVDI-----------------------------------------YTNSWGPSE------GF--------------------------------------------------------------EYAGPG-SVTEN-AFYD----GV-----T--------------------------------------------------------------------------KGRGGKGSIY--V----------------WAAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GG-L--------RDNCNADGY--------VNNIYT---IP---IT--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--A--------D-GKA-ADYA-------------------------------------------------------------------EVCAPVF------------------------AATYS-G-------------NE-----------------------------------------------RKTL------------------------------------------------------------------TS--------------------------------------------------------------------------------------------------------------------------------TSLSSS------CV--TGLRG------TSFSTPLAA----G---------------------------M------------------IALA----LQ------------TNPSL----------------------------------------------------------------------------------TC------------------RDVQHLV-------V---------------------------------------------------------------------------------------------------------------------------------------- 954
 955 -------------WYMNHCTGLD----MH-----------VTGAW-------VRG-YTGE--------------------------G-V--NM--------------A--------------------VVD---------------------------D--------------GLQT-D------H-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--Y----------E--------------------------AALSTDVV-------D-GD-------------RDPSHPAD---------ST----------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TK-V-----------------------AGVAT----AVANN--------------------------------------------------------------SLCG---VGV--APA-A----------KV-----------------G--G--K--RRL--RTYLEVND-------------------------------------A--------QDA--------------------------TA--YSF--------------------------------------------GQDAVDV-----------------------------------------YISSWGPNDFAEVD-G-------------------------------------------------------------------PG-PLLKQ-ALRN----GA-----T--------------------------------------------------------------------------TGRGGRGNVY--I----------------FSSG-NG-----------------------------------------------------------------------------------------------------------------------------------------------------------------------GGGQY--------PDSCAFDGF--------VNNPYS---LA---FG--S------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--G--------T-GRR-AAHS-------------------------------------------------------------------EACSALI------------------------ASVFAED-------------RN----------------NA---------------------------EGHEMV-------------------------------------------------------------------T--------------------------------------------------------------------------------------------------------------------------------TKITSE------CT--GDFYQ------SSAGAPLAG----G---------------------------I------------------LALA----IN------------ANAAL----------------------------------------------------------------------------------TW------------------RDLKHLI-------VQTSQPDSRLTSMD------------------------TTDWI--------------------------------------------TNAAGHRVS----------------------------------------- 955
 956 ----------------------------------------IREAW-------EAG-YNAS--------------------------R-V--TV--------------A--------------------VVD---------------------------D--------------GVDV-G------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RSAF----------S--------------------------PRVSFDFV-------KFGS-------------LPIPTISK---------ET----------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------TQ-C-----------------------AGLVS----MEGNQ----------------------------------------------------------------CG---LGV--GHG-A----------TL-----------------G--A--I--RLL--GQ-DELND-------------------------------------A--------LEG--------------------------DA--LAF--------------------------------------------EKDLIDI-----------------------------------------YSVSWGPKD----D-GL--------------------------------------------------------------TAEKPA-KFTQD-AIKN----GA-----V--------------------------------------------------------------------------FGRNGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGEN--------GDNCALDGY--------VSNEYT------------V------------------------------R---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------C--S--------S-GVP-SAYA-------------------------------------------------------------------EGCSAVL------------------------AAV------------------------------------S---------------------------GGDSMI------------------------------------------------------------------QT--------------------------------------------------------------------------------------------------------------------------------TGLEST------CS---SISG------SSASAAIAS----G---------------------------I------------------IALA----LE------------ANPAL----------------------------------------------------------------------------------SQ------------------RDIQHLI-------VHSS------------------------------------------------------------------------------------NSSAVK------------------------------------------- 956
 957 ----------------------------------------IREAW-------EDG-FNAS--------------------------R-V--TV--------------A--------------------VVD---------------------------D--------------GVDI-K------H-------------V---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KSAF----------S--------------------------PRVSFDFV-------RFGD-------------LPTPKNSK---------EF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------TQ-C-----------------------AGLVA----MEGQQ----------------------------------------------------------------CG---LGV--GHG-A----------TL-----------------G--A--I--KLL--GQ-DFLND-------------------------------------A--------LEG--------------------------DA--LAF--------------------------------------------QKDLIDI-----------------------------------------YSVSWGPKD----D-GK--------------------------------------------------------------SAEKPA-KFTEE-AIKN----GA-----L--------------------------------------------------------------------------HGRNGKGNIF--V----------------WASG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGVN--------GDNCAYDGY--------VSNEYT---LS---FG--V------------------------------I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D--A--------S-GAP-AAYG-------------------------------------------------------------------EGCSSVL------------------------AAV------------------------------------S---------------------------GGDAMI------------------------------------------------------------------QT--------------------------------------------------------------------------------------------------------------------------------TGLEST------CS---SISG------SSASAAIAS----G---------------------------I------------------ISLV----LD------------ANPTL----------------------------------------------------------------------------------SQ------------------RDIQHLI-------ARTS------------------------------------------------------------------------------------NASAIRDVELYE------------------------------------- 957
 958 ---------------------------MN-----------VLPAW-------ERT-QKGE--------------------------G-V--VV--------------G--------------------VID---------------------------D--------------GIFT-N------Q-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDNL----------D--------------------------------------------T--------------SDSTP--------NIPQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TN-C-----------------------AGIIA----AVHNN--------------------------------------------------------------SFCG---VGV--AYR-A----------KV-----------------A--G--I--KMF-SGAITELSD-------------------------------------A--------QEA--------------------------SA--LSH--------------------------------------------EYQRISI-----------------------------------------YSCSWGPSD----W-NN--------------------------------------------------------------ALEGPD-TVAKE-ALTM----TA-----Q--------------------------------------------------------------------------EGRSGRGSIF--V----------------FSTG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTY--------NDSCAYNGY--------INTNNT---IG---IG--G------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L--Q--------D-GSI-PSFA-------------------------------------------------------------------ESCTSVF------------------------AVTYS-------------------------------RDYT---------------------------GDTANL------------------------------------------------------------------VV--------------------------------------------------------------------------------------------------------------------------------PSRASG------CG--TTFSG------TSPAAAMAA----G---------------------------V------------------FTLV----LS------------ANDQL----------------------------------------------------------------------------------SV------------------RDVQHL------------------------------------------------------------------------------------------------------------------------------------------------- 958
 959 ---------------------------MN-----------VLPAW-------ERT-QEGE--------------------------G-V--VV--------------G--------------------VID---------------------------D--------------GIFT-N------Q-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RDNL----------D--------------------------LGLSYDIF-------E-ET--------------TDPTP--------NIEQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TN-C-----------------------AGIIA----AVHNN--------------------------------------------------------------SFCG---VGV--AYK-A----------KV-----------------A--G--I--KMF-SGAMTDISD-------------------------------------A--------QEA--------------------------SA--LSH--------------------------------------------EHQHISI-----------------------------------------YSCSWGPSD----W-NN--------------------------------------------------------------ALDGPD-TVARE-ALVM----AA-----R--------------------------------------------------------------------------EGRNGKGSIF--V----------------FSTG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGTY--------NDSCAYNGY--------VNTNNT---IG---IG--G------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L--Q--------D-GSI-PSFA-------------------------------------------------------------------EACTGVF------------------------AVTYS-------------------------------RDYT---------------------------GDTADL------------------------------------------------------------------VV--------------------------------------------------------------------------------------------------------------------------------PYRSSG------CR--TSFSG------TSPAAAMAA----G---------------------------V------------------FSLV----LS------------ANDRL----------------------------------------------------------------------------------SV------------------RDVQHLV-------TRTSRNSGICGQ----------------------------TWK--------------------------------------------ENSAGFRVS----------------------------------------- 959
 960 ---------------------------MN-----------VLPAW-------VRG-YYGQ--------------------------G-V--VV--------------G--------------------VVD---------------------------D--------------GIFL-E------N-------------P---------D--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MPNI----------A--------------------------EGLSYSVV-------D-DS--------------LDPTP--------SAAVF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TR-C-----------------------AGIVA----AKANN--------------------------------------------------------------NFCG---VGV--APK-A----------KI-----------------A--G--M--KLF-VGASADLTD-------------------------------------A--------EEA--------------------------LA--LSH--------------------------------------------SYNDISI-----------------------------------------YSCSFGPSD----Y-NN--------------------------------------------------------------VLEGPD-TLTYA-AMKL----SA-----E--------------------------------------------------------------------------KGRNGKGSIY--M----------------FSAG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNY--------GDSCAYNGY--------INNIYA---IG---IS--A------------------------------V---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------L--T--------D-GSL-ARYD-------------------------------------------------------------------EACTSIF------------------------GVTYS-------------------------------RQY----------------------------DDNTTL------------------------------------------------------------------VV--------------------------------------------------------------------------------------------------------------------------------PYGPGG------CK--TKFSA------TSAAAAMGS----G---------------------------V------------------IALV----LS------------ANEAL----------------------------------------------------------------------------------SA------------------RDVQHLI-------ARTSKNNGICGN----------------------------TWK--------------------------------------------MNAAGFRVS----------------------------------------- 960
 961 ----------------------DPLFNEQFNLHNTGQKMGIPGEDLGLGNVFKNRQYTGK--------------------------G-V--VT--------------I--------------------VND---------------------------D--------------GVNY-E------H-------------P---------D--------------------------------LKDAIDSRYLINLGDNTTHVLPDKGY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HG-------SG-C-----------------------AGVIA----SKWDN-----------------------------------------------------------------GVCGAGI--APG-V--TLGAA---KFPN--SIFS-TEYIVKCFGFKDSE-----------------------------------------------------V---------------------------------------------------------------------------------------------KI-----------------------------------------HSNSWEIDEC------SKE------------------------------------------------------------GCPGGEQMHGFHDVISKASKSGVN-------------------------------------------------------------------------------------------I---------------VFAAG-NNAELLGDTNFRTISN--WREN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IV---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------S--T--------FRGQHAFYSEVSSTITVNAPSSYGSNAIG------------------------------------------------------LGEK-------------------------YTP-------------S---------------------------------------------------V------------------------------------------------------------------QT--------------------------------------------------------------------------------------------------------------------------------------ISPKGK-ECNPSFGG------TSASSPMVA----G---------------------------V------------------LALI----LEAN------------PKLK----------------------------------------------------------------------------------P------------------RDLSYII-------SITATINDPKHGSWTKNAAGLYYSPYFGF------------------------------------------------------------------------------------------------------------ 961
 962 ----------------------------------------------------HDIGITGK--------------------------G-I--KV--------------V--------------------MVD---------------------------S--------------GFYR--------HPFFLTRQYHI---N---------S--------------------------------VILGPDTFEPIHD--------ET-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHGTGCAANIFS-L-----------------------APEVD------------------------------------------------------------------------------LTVVKMN----------------------------------------------------MF-------------------------------------MAMGAFEKAVEQ--------------------------NP------------------------------------------------------DI-----------------------------------------ITCSWGFPTPPNELTA-----------------------------------------------------------------QQAIFAVKIADAVKK----GI-----T--------------------------------------------------------------------------------------V---------------IFASG-NGGQPFPGMHPDVISVGG--VF--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V---AK---DG--S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ME--ATPFA----------------------------------------------------------------------------------------SGYKSEI------YQNRQVPDICGLCGLPPIAAYIMLP-----------------------------------------------------------------V-----------------------------------------------------------------------------------------------------------------------------------------------------------------------DPDEKYDRERAEIKYPLGDETSPSD---------GWAAF---------SG------TSTAAPQIA----G---------------------------I------------------CALL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KQVNKKLTPLQLRDILKETARDVIKGHSQQNNPAQPGHDVATGFGLVNASKAVE-------- 962
 963 ---------------------------------------------------------------------------------------DL--VV--------------A--------------------VID---------------------------S--------------GIWPYSELFGSDSPPPPGWENKCENITCNNKIVGARS-------------YYPK-KEKYKWVEE------KSVIDVT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TH-V-----------------------ASIVA----GRKVE-----------------------------------------------------------------KAGYFGL--A-----------EGTMRGGVPNAKIAVYKTCWRVIRKNGREDSVCREDNILKAIDD-------------------------------------A----------------------------------------------------------------------------------------IADKVDI-----------------------------------------ISYSQG---FQFT------------------------------------------------------------------PLQKDKVSWAFLRALKN----GI-----L--------------------------------------------------------------------------------------T---------------SAAAG-NYANNGKF--YY-------------------------------------------------------------------------------------------------------------------------------------------------------------TVANGAPW---------------------------V---MT---VA--A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SLKDRIFE-TKLE-----------LEGED------------------------------------------------------------------------KPII------VYDTI--NTFE--TQDSFYPLLNEKAPP-------------ESTRKRELIAERNGYSILSNYDEKDKGKDVFFEFAQINLLDEAIKEREKGAIV------------------------------------------------------------------LGGKSYDFNES-IKLQFPIASIFLDEQKKGKLW---DYYKKDQSKERLAKIHKTEEIPREEGWVPTVAHLSSRGPNCDSFLANILKNSHMNNCFQPDIAAPGLDIIAGWPENVKLSSDRPANDYRHLRF-----------------NIMSG------TSMACPHAT----G----------------------------------------------LALYLKSFKRWSPSAIKSALMTTSSEMT--------------------------------------------------------------------------------------------------------DDD------------------------------------------------------------------------------------------------------------------------NEFAYGSGHLNATK----------- 963
 964 ----------------------------------------------------------GK--------------------------G-V--TI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LQ-------------------QTSDGRP-KIVDII-DTTGSGDVDVSTVVEPKD-----------GEIAGLSGRTLKVPASW----ENPTGRYHIGVKNMYELFPKQLRDRTQ----------V-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAHG-------TH-V-----------------------ACIAA----GNFPD-------------------------------DP------------------------------ERN----GI--APG-A--QIVAI---KIGDSRLST------------ME--T------------GSA-------------------------------------L--------IRA--------------M-----------IA---VI--------------------D-----Q------K----------C----DL-----------------------------------------VNFSYGEAAHWPDK-GRVCDVI--------------------SE-----------------------------------AVNK------------H----GV-----I--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------ALTTVGT---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------I---I---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GS--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSALK-----AT--GVPYT-----------------------------------------------------------------PYT--------------V---------------------KTAL-------ENT---------------------------------------------------------------------------------------------------AQKV---EGVEVFAQGHGVLQVEKAFD-------- 964
 965 ---------------------DHEFPIHGLLPKR-ETGASAFLAK-------YPE-YDGR--------------------------G-V--TI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LQ-------------------QTSDGRP-KIVDII-DTTGSGDVDVSTVVEPKD-----------GEIVGLSGRTLKVPASW----ENPTGRYHIGVKNMYELFPKQLRDRTQ----------KDKKEKTWDPPHRVALAEAIRKL--------------------------------DEFDTAHPNPTAQ------------------------DEKLQREDLQAQLDILTSQ---EKKYSDPGPVCDCLVWHDG---------NTW-----------------------------------------------------------------------------------RAVLDTSE----------------------------TGD----------------------------------------------------------------------LESCTVLASYREQHQFCIFSLFV-------MFNYSVNIYDDGKVLNICANG----------------GAHG-------TH-V-----------------------ACIAA----GNFPD-------------------------------DP------------------------------ERN----GI--APG-A--QIVAI---KIGDSRLST------------ME--T------------GSA-------------------------------------L--------IRA--------------M-----------IA---VI--------------------D-----Q------K----------C----DL-----------------------------------------VNFSYGEAAHWPDK-GRVCDII--------------------SE-----------------------------------AVNK------------H----GV-----I--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------ALTSVGT---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------I---IG---VGAFV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTAEY---SLREKLP-SNQ-YTW-----S--S--------R-GPT-I----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GS--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSALK-----AT--GVPYT-----------------------------------------------------------------PYT--------------V---------------------KTAL-------ENT---------------------------------------------------------------------------------------------------AQKV---EGVEVFAQGHGVLQVEKAFD-------- 965
 966 ---------------------DKNFPVAGLLPKN-ETGAAAFLTK-------YPE-YDGR--------------------------G-V--VI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LQ-------------------TTTDGLP-KILDII-DATGSGDVITSTVVEVRD-----------GEITGLTGRKLKIPLNW----ENPSGKYHIGVKNAYELYPKGLKERVQ----------KDRKEKLWDTYHKPAIAEATRKL--------------------------------EAYDAAHPNVTKQ------------------------EEKLERENLVAMLDVLNNA---DKKYSDPGPVYDCLVFNDG---------NTW-----------------------------------------------------------------------------------RAVIDTSA----------------------------CGD----------------------------------------------------------------------LASCTVLANYKEDHQKATLSNLD-------MLNYSVNIYDDGNVLSIVTNA----------------GSHG-------TH-V-----------------------AGIAA----AHFAD-------------------------------NP------------------------------EKN----GI--APG-A--QIVAI---KIGDSRLGS------------ME--T------------GSA-------------------------------------L--------VRA--------------M-----------IA---VI--------------------E-----H------K----------V----DL-----------------------------------------VNFSYGEAAHWPNG-GRVCDVI--------------------SE-----------------------------------AVNN------------H----GI-----I--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------ALSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------I---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MSAAEY---SLREKLP-GMP-YTW-----S--S--------R-GPT-V----------------------------------------------------------------------D-----GALGVSIC-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------TSVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GS--QLMNG------TSMSSPNAC----G----------------------------------------------GIGL----ILSGLK-----KE--GIAYT-----------------------------------------------------------------PHS--------------I---------------------RRAV-------EST---------------------------------------------------------------------------------------------------AQSL---DNVERFSQGYGLLQVVQAFE-------- 966
 967 ------------------------FPVFGLLPKK-ETGAWSFVGK-------YPD-HDGK--------------------------G-V--TI--------------A--------------------VLD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LK-------------------VTSDGRP-KIIDII-DATGSGDVDTSSVVEVKD-----------GQITGLTGRTLKIPTDW----SNPSGQYHIGVKAAQDLYPKGLKDRMV----------KERREKLWDRAHRATAANVMQQC--------------------------------SEFDAAHPEP-NQ------------------------EEKLIKEDLMAQAEILLSL---EKKYADCCPVYDCVVFHDG---------QTW-----------------------------------------------------------------------------------RACLDTSE----------------------------RGD----------------------------------------------------------------------LAECPCMAPFREERQYATLSQDD-------MLNYSFNIYNEGKTLEVVSNA----------------GSHG-------TH-V-----------------------ACIAA----GCFPD-------------------------------EP------------------------------EKN----GV--APG-A--QVVAI---KIGDSRLGS------------ME--T------------GAA-------------------------------------L--------TRA--------------M-----------IY---VM--------------------N-----N------K----------C----DL-----------------------------------------VNYSYGEGSHIPNV-GRVCDVL--------------------SE-----------------------------------AVVK------------H----GV-----I--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------ALSTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------I---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAAEY---SLRERLP-GNL-YTW-----S--S--------R-GPT-Q----------------------------------------------------------------------D-----GALGVCIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GS--QLMNG------TSMSSPNAC----G----------------------------------------------CVAL----ILSAMK-----AK--ALPYT-----------------------------------------------------------------PFS--------------V---------------------RQAL-------ENT---------------------------------------------------------------------------------------------------ALKV---NSLDHFALGHGLVQVEKAFD-------- 967
 968 ------------------------FPLDGLLPKK-ETGAYSFLTK-------YPN-YDGR--------------------------R-V--LI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LQ-------------------ETPDGSP-KIVDII-DTTGSGDVDTSKVEEVKD-----------GEITGVTGRKLKIPDTW----NNPSGLYHVGVKPIFELFPKKLQERFI----------KERKEKNWDPAHREAVADTTRKL--------------------------------EQYEAS-----GQ------------------------DDKQEKENLQSCIDVLNNM---EKTYEEAGPMLDCVVFHDG---------ATW-----------------------------------------------------------------------------------RACVDMTG----------------------------RGE----------------------------------------------------------------------LCECKLLASYHEEHQYGTFSRVD-------MMNYGVNIYNDGNTLEIVTNA----------------GAHA-------SH-V-----------------------AGIAA----GYFPD-------------------------------QP------------------------------ERN----GV--APG-A--QIISI---KIGDTRLGS------------ME--T------------GTS-------------------------------------L--------VRA--------------M-----------IK---VI--------------------E-----Y------K----------C----DL-----------------------------------------VNYSYGEACSWPNS-GRVIDIL--------------------SE-----------------------------------AVNK------------H----GV-----V--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------ALSTAGC---------------------------------------------------------------------------------------------------------------------------------------PGGTSS-A---------------------------L---IG---VGAMV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAAQY---SLMEKLP-SNQ-YTW-----S--S--------R-GPT-H----------------------------------------------------------------------D-----GDLGVTIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GN--QLMNG------TSMSSPNAC----G----------------------------------------------CIAL----VLSGLK-----AN--GIEYT-----------------------------------------------------------------PSS--------------V---------------------KRAL-------INT---------------------------------------------------------------------------------------------------A---------------------------------- 968
 969 -------------------ATEEPFPFHGLLPKK-ETGASSFLCR-------YPE-YDGR--------------------------G-V--LI--------------A--------------------VLD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------VTTDGKP-KIIDII-DTTGSGDVNTATEVEPKD-----------GEIIGLSGRVLKIPANW----TNPLGKYHIGIKNGYDFYPKALKERIQ----------KERKEKIWDPIHRVALAEACRKQ--------------------------------EEFDIANNGS-SQ------------------------ANKLIKEELQSQVELLNSF---EKKYSDPGPVYDCLVWHDG---------ETW-----------------------------------------------------------------------------------RACVDSNE----------------------------NGD----------------------------------------------------------------------LSKCAVLRNYKEAQEYSSFGTAE-------MLNYSVNIYDDGNLLSIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GHFPE-------------------------------EP------------------------------ERN----GV--APG-A--QILSI---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---VI--------------------N-----H------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------NE-----------------------------------AVWK------------H----NT-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-A----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSGLK-----AN--NVDYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AIKA---DNIEVFAQGHGIIQVDKAYD-------- 969
 970 -------------------ATEEPFPFHGLLPKK-ETGAASFLCR-------YPE-YDGR--------------------------G-V--LI--------------A--------------------VLD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------VTTDGKP-KIVDII-DTTGSGDVNTATEVEPKD-----------GEIVGLSGRVLKIPASW----TNPSGKYHIGIKNGYDFYPKALKERIQ----------KERKEKIWDPVHRVALAEACRKQ--------------------------------EEFDVANNGS-SQ------------------------ANKLIKEELQSQVELLNSF---EKKYSDPGPVYDCLVWHDG---------EVW-----------------------------------------------------------------------------------RACIDSNE----------------------------DGD----------------------------------------------------------------------LSKSTVLRNYKEAQEYGSFGTAE-------MLNYSVNIYDDGNLLSIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GHFPE-------------------------------EP------------------------------ERN----GV--APG-A--QILSI---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---VI--------------------N-----H------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------NE-----------------------------------AVWK------------H----NI-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-A----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----ILSGLK-----AN--NIDYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AVKA---DNIEVFAQGHGIIQVDKAYD-------- 970
 971 -------------------ATEEPFPFHGLLPKK-ETGAAAFLCR-------YPE-YDGR--------------------------G-V--LI--------------A--------------------VLD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------VTTDGKP-KIIDII-DTTGSGDVNTATVVEPKD-----------GEIVGLSGRVLKIPVTW----TNPSGRYHIGIKNGYDFYPKALKERIQ----------KERKEKIWDPVHRAALAEACRKQ--------------------------------EEFDVANNCP-SQ------------------------ANKLIKEELHSQVELLNSF---EKKYSDPGPVYDCLVWFDG---------ETW-----------------------------------------------------------------------------------RACIDSSE----------------------------DGD----------------------------------------------------------------------LSKSTVLRNYKEAQEYGSFGAAE-------MLNYSVNIYDDGNLLSIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GHFPE-------------------------------EP------------------------------ERN----GV--APG-A--QILSI---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---VI--------------------N-----H------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------NE-----------------------------------AVWK------------H----NI-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-A----------------------------------------------------------------------D-----GALGVSVS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSGLK-----AN--DVNYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AVKA---DNIEVFAQGHGIIQVDKAYD-------- 971
 972 -------------------AAEEPFPFQGLLPKK-ETGAAAFLAR-------FPD-FDGR--------------------------G-V--LL--------------A--------------------VLD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------ITTDGKP-KIIDII-DTTGSGDVTTCTVVEAKD-----------GEIIGLSGRTLKIPTNW----VNPSGKYHIGLKNGYDIYPKALKERIQ----------KERKEKLWDPLHRLALAEACRKQ--------------------------------EEFDAAHSSP-SQ------------------------VNKLIKEELQNQVELLNSF---EKKYSDPGPVYDCVVWYDG---------ETW-----------------------------------------------------------------------------------RACIDTSE----------------------------SGD----------------------------------------------------------------------LTSCTVLRTYKEAQEYGSFGTSE-------MLNYSVNIYDDGNLLSIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GYFPE-------------------------------EP------------------------------ERN----GV--APG-A--QILAI---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---AI--------------------K-----Y------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------NE-----------------------------------AVWK------------H----NV-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMIAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-T----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSGLK-----AN--DIHYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AVKA---ENIEVFAQGHGVIQVDKAYD-------- 972
 973 -------------------AVEDPFPFQGLLPKK-ETGAAAFLSR-------HPE-YDGR--------------------------G-V--LV--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------ITTDGKP-KIIDII-DTTGSGDVNTSTIVEVKD-----------GEIIGLSGKTLKIPTDW----INPSGKYHIGLKNGYDFYPKALKERIQ----------KERKEKLWDPVHRLALTEACRRQ--------------------------------DEFEAAHVSP-SQ------------------------ESKLMKEELQTQVELLNSF---EKKYSDPGPVYDCLVWHDG---------ETW-----------------------------------------------------------------------------------RACIDASE----------------------------SCD----------------------------------------------------------------------FPNCTVLRNYREAQEYGSFGTSE-------MLNYSVNIYDEGNLLSIVTSG----------------GSHG-------TH-V-----------------------ASIAA----GHFPD-------------------------------EP------------------------------DRN----GV--APG-A--QILAI---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---TI--------------------K-----Y------K----------C----DL-----------------------------------------VNYSYGEATHWPNA-GRICEVI--------------------NE-----------------------------------AVWK------------H----NV-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTN-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-T----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSGLK-----AN--GVHYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AVKV---ENIQVFAQGHGIIQVDKAYD-------- 973
 974 --------------------AEEPFPFHGLLPKK-ETGAASFLTK-------YPE-YDGR--------------------------G-V--LI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------MQ-------------------ITTDGKP-KIVDII-DTTGSGDVNMSTVVEVKE-----------GSVSGLTGRTLKIPAAW----VNPSGKYHIGVKNGYDFFPKALKERIQ----------KERKEKLWDPTHRAALAEASRRT--------------------------------EEFDQTHTNP-SQ------------------------MEKLQKEELQCHVELLGML---EKKYSDPGPVYDCISWHDG---------VTW-----------------------------------------------------------------------------------RAVVDTSE----------------------------CGD----------------------------------------------------------------------LSSCTVLSSYRERQEFCTLGFAE-------MLNFSVNIYDEGNTLCIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GHFPD-------------------------------EP------------------------------ERN----GV--APG-A--QILAL---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---VI--------------------N-----Y------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------TE-----------------------------------AVQK------------Y----NV-----M--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------CLTTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-PNQ-YTW-----S--S--------R-GPC-T----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----VLSGLK-----QN--GLRPT-----------------------------------------------------------------VPA--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AQKV---EEIEVFAQGHGIIQV------------- 974
 975 -------------------ATEEPFPFHGLLPKKGDRGPPPFLLR-------IFN-ERER--------------------------E-I--LV--------------I--------------------KLD---------------------------T--------------AVGV-G------D-------------K---------G--------------------------------MQ-------------------VTTDGKP-KIIDII-DTTGSGDVNTATVVEPKD-----------GEIIGLSGRVLKIPASW----INPSGRYHIGIKNGYDFYPKALKERLQ----------KERKEKIWDPVHRVALAEACRKQ--------------------------------EEFDVANNCP-SQ------------------------ANKLIKEELQSQVELLNSF---EKKYSDPGPVYDCLVWHDG---------EAW-----------------------------------------------------------------------------------RACIDSNE----------------------------DGD----------------------------------------------------------------------LSKSTVLRNYKEAQEYGSFGTAE-------MLNYSVNIYDDGNLLSIVTSG----------------GAHG-------TH-V-----------------------ASIAA----GHFPE-------------------------------EP------------------------------ERN----GV--APG-A--QILSV---KIGDTRLST------------ME--T------------GTG-------------------------------------L--------IRA--------------M-----------IE---VI--------------------N-----H------K----------C----DL-----------------------------------------VNYSYGEATHWPNS-GRICEVI--------------------SE-----------------------------------AVWK------------H----NI-----I--------------------------------------------------------------------------------------Y---------------VSSAG-NN--------GP---------------CLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMVAEY---SLREKLP-ANQ-YTW-----S--S--------R-GPS-A----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPNW-------------------------------------------------------------------------------------------------------------------------TL-R-----------GT--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----ILSGLK-----TN--DVNYT-----------------------------------------------------------------VHS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AVKA---DNIEVFAQGHGIIQVDKAYD-------- 975
 976 ------------------------FPIHCMVPKK-EIGALNFLNK-------YPD-YNGQ--------------------------G-I--TI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------L---------G--------------------------------LQ-------------------ETPDGRP-KIIDII-DTTGSGDVDMSVVVTPDE--D--------GCVQGLTGRKLKIPTSW----NNPNGKFNIGIKNLHQIFPKGLKDRLT----------KEDKEIGWERSHKLKTAMAMAKL--------------------------------NDFIANDNDSLP-------------------------DKKMQKENLQAAVDFLDKV---DKNWSDPGPVADCIVFHDG---------NTF-----------------------------------------------------------------------------------QACVDISL----------------------------CGD----------------------------------------------------------------------LQSAPLLTSYSESQKFATISRAA-------MLNYSVNIYEEGKVLCIVANG----------------GSHG-------TH-V-----------------------AAITA----GYFPE-------------------------------EP------------------------------ERN----GL--APG-A--QIVAI---KIGDSRLAT------------ME--T------------GTG-------------------------------------I--------IRG--------------I-----------TE---AV--------------------K-----H------G----------C----HL-----------------------------------------ANLSYGEASHWPGS-GKICEVM--------------------DQ-----------------------------------AVTK------------H----NL-----I--------------------------------------------------------------------------------------I---------------VSSAG-NN--------GP---------------CLSTVGS---------------------------------------------------------------------------------------------------------------------------------------PGGTTE-N---------------------------I---IG---VGAWV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMTAEY---SMTEKLP-SNQ-YTW-----S--S--------R-GPC-T----------------------------------------------------------------------N-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------TSVPNW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------GS--QLMNG------TSMSSPNAC----G----------------------------------------------AIAL----ILSGLK-----GR--DISYT-----------------------------------------------------------------PYS--------------I---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------AFKQ---ENVEIFAQGFGLVQVNECFD-------- 976
 977 ------------------------FPLQDLLPKQ-ETAADRFLRQ-------YPD-YDGR--------------------------G-T--II--------------A--------------------IFD---------------------------T--------------GVDP-G------A-------------D---------G--------------------------------LQ-------------------MTSDGRR-KIIDCI-DCTGSGDVDTSTVSSIDD--D--------GCVTGLTGRKLQIPAEW----ENPTGKFHLGIKHATELFPSPLCDRLK----------KEYRKKKWAPSHSKCTADAIREL-----------------------------------QQSESKGQKQTF----------------------LDELMREELQQRTEQLKNL---DKIGDESLPIFDCVVFHNG---------SVW-------------------------------------RYRYNILA-------------------------MRFIRTKIFTPFSRAVIDTTE----------------------------TGN----------------------------------------------------------------------LSKCTVLPEFRLQPVYGTFGEDD-------LLNYTISVYDDGNRLSIVTNA----------------GSHG-------TH-V-----------------------ACITS----GYFES-------------------------------TP------------------------------EKN----GI--APG-A--QILSV---KIGDTRLDS------------ME--T------------GPG-------------------------------------I--------VRG--------------L-----------IA---SK--------------------N-----Y------G----------C----DL-----------------------------------------INMSYGEACQKPNE-GRIMELC--------------------NE-----------------------------------FVDE------------H----DI-----I--------------------------------------------------------------------------------------M---------------VSSAG-NN--------GP---------------AMSTVGS---------------------------------------------------------------------------------------------------------------------------------------PGGTCS-S---------------------------V---IS---VGAHV------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAAQY---SLLERVQ-SMQ-YTW-----T--S--------R-GPC-I----------------------------------------------------------------------D-----GALGVSIS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPKW-------------------------------------------------------------------------------------------------------------------------TL-S-----------SS--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----ILSGLK-----AC--QIPFS-----------------------------------------------------------------PSS--------------V---------------------RRAV-------ENT---------------------------------------------------------------------------------------------------ASSI---TGEDHFSMGYGLLQVDKAFE-------- 977
 978 --------------------------------KK-ETGAERFLSR-------FPE-HNGK--------------------------N-V--VI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LSG--------------LWVMKTPDGKS-KILGLY-DSSGSGDVDTSVVRTTTR--EIG------RVIDGLTGRKLKIPNGW----TNPSGKWHVGVKAAFELFPNLLKTRLQ----------KEFVEKEWNPAHLRALAEAEREL--------------------------------RDFELHNRIDGNIIAVIDNTFIDVVFGISIQTISLIPVSKLKKEDLQARVDILNSL---NSKNNIAGPFYDCIVFNDG---------SYW-----------------------------------------------------------------------------------KAAIDTTK----------------------------DGD----------------------------------------------------------------------LRDIPCLCSYKIAQHWVKFGYN-------------VNVYDNGNLLSIVTTGGQSSIHSLNPLILSSPGSHG-------TH-V-----------------------ASIAA----AYFPS-------------------------------SP------------------------------EKN----GV--APG-A--QIIGI---KVGDTRLST------------ME--T------------GPS-------------------------------------L--------LRA--------------C-----------NI---LA--------------------E-----L------H----------C----DL-----------------------------------------INYSYGEASHWTNK-GAVLEEF--------------------IS-----------------------------------LVRK------------H----NV-----V--------------------------------------------------------------------------------------F---------------VTSAG-NN--------GP---------------GLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGNTE-A---------------------------L---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEGTY---SMLKSKP-GIP-YTW-----S--S--------R-GPA-A----------------------------------------------------------------------D-----GDLGVSVT-----------------A-----P-------------G-----------------GA--------------------------------F------------------------------------------------------------------TSVPTW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------CS--QMMNG------TSMSSPNTC----G----------------------------------------------NIAL----LLSAIK-----YR--GYDYT-----------------------------------------------------------------PAL--------------I---------------------KRVI-------EKT---------------------------------------------------------------------------------------------------ATPL---GSHDPFSIGHGVIQVDKAYD-------- 978
 979 ----------------------KPFPEHCLIPKK-ETGAERFLSR-------FPE-HNGK--------------------------N-V--VI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LS-------------------KTPDGKS-KILGLY-DSSGSGDVDTSVVRTTTR--EIG------RVIDGLTGRKLKIPNGW----TNPSGKWHVGVKAAFELFPNLLKTRLQ----------KEFVEKEWNPAHLRALAEAEREL--------------------------------RDFELHNRIDGNI------------------------KNRLKKEDLQARVDILNSL---NSKNNIAGPFYDCIVFNDG---------SYW-----------------------------------------------------------------------------------KAAIDTTK----------------------------DGD----------------------------------------------------------------------LRDIPCLCSYKIAQHWVKFGYND-------MFNYSVNVYDNGNLLSIVTTG----------------GSHG-------TH-V-----------------------ASIAA----AYFPS-------------------------------SP------------------------------EKN----GV--APG-A--QIIGI---KVGDTRLST------------ME--T------------GPS-------------------------------------L--------LRA--------------C-----------NI---LA--------------------E-----L------H----------C----DL-----------------------------------------INYSYGEASHWTNK-GAVLEEF--------------------IS-----------------------------------LVRK------------H----NV-----V--------------------------------------------------------------------------------------F---------------VTSAG-NN--------GP---------------GLSTVGC---------------------------------------------------------------------------------------------------------------------------------------PGGNTE-A---------------------------L---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEGTY---SMLKSKP-GIP-YTW-----S--S--------R-GPA-A----------------------------------------------------------------------D-----GDLGVSVT-----------------A-----P-------------G-----------------GA--------------------------------F------------------------------------------------------------------TSVPTW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------CS--QMMNG------TSMSSPNTC----G----------------------------------------------NIAL----LLSAIK-----YR--GYDYT-----------------------------------------------------------------PAL--------------I---------------------KRVI-------EKT---------------------------------------------------------------------------------------------------A---------------------------------- 979
 980 --------------------------LESLMPKK-ETGVDRFLAK-------HPE-YDGR--------------------------G-A--LI--------------A--------------------IFD---------------------------S--------------GVDP-A------A-------------A---------G--------------------------------LQ-------------------TTSDGKP-KILDVI-DCTGSGDVDTSKVVKADA--D--------GAIVGASGTRLVVNPLW----KNPSEQWHIGCKLVYELFTDTLISRLK----------KERKKK-WDEENQEAISGALSQL--------------------------------NEFEKKHSKP-DDA-----------------------KLKMAHEDLQNRLDCLRKQ---AEGYDDRGPVIDVVVWHDG---------DVW-----------------------------------------------------------------------------------RVAVDTQGL---------------------E-GDKNCGK----------------------------------------------------------------------LADFVPLTNYRHERKFGIFSKLD-------ACSFVANVYDDGNLVSIVTDC----------------SPHA-------TH-V-----------------------AGIAA----AFHPE-------------------------------QP------------------------------LLN----GV--APG-A--QLISC---RIGDTRLGS------------ME--T------------GTG-------------------------------------L--------VRA--------------L-----------IA---AV--------------------E-----H------K----------C----DL-----------------------------------------INMSYGEPTLLPDY-GRFIDLV--------------------NE-----------------------------------VVDK------------H----RI-----I--------------------------------------------------------------------------------------F---------------ISSAG-NN--------GP---------------ALNTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTSS-S---------------------------I---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGAH---CVVQPPSEGME-YTW-----S--S--------R-GPT-A----------------------------------------------------------------------D-----GDLGVSIS-----------------A-----P-------------G-----------------GA--------------------------------V------------------------------------------------------------------APVPTW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------SR--MLMNG------TSMSSPSAC----G----------------------------------------------GVAL----LVSAMK-----AE--GIPLS-----------------------------------------------------------------PYT--------------V---------------------RKAI-------ENT---------------------------------------------------------------------------------------------------A---------------------------------- 980
 981 -------------------KLNESTFIASLMPKK-EIRADCFIEA-------HPE-YDGR--------------------------G-V--VI--------------A--------------------IFD---------------------------S--------------GFDP-S------A-------------A---------G--------------------------------LH-------------------VTSDGKP-KVLDVI-DCTGSGDIDTSTVVKANE--D--------GHIRGASGATLVVNSSW----KNPTGEWRVGSKLVYQLFTDDLTSRVKVAIRVVTFLAKERRKS-WDEKNQEEIAKAVNNL--------------------------------YDFDQKHSKV-EDA-----------------------KLKKTREDLQSKVDFLKKQ---ADKYEDKGPVIDAVVWHDG---------EVW-----------------------------------------------------------------------------------RVALDTQSL---------------------E-EDPDSGK----------------------------------------------------------------------LADFSPLTNYRQ-----------------------------GKVLSIVTDS----------------SPHG-------TH-V-----------------------AGIAT----AHHPE-------------------------------H-------------------------------LLN----GV--APG-A--QIISC---KIGDSRLGS------------ME--T------------GTG-------------------------------------L--------TRA--------------L-----------IA---AL--------------------E-----H------N----------C----DL-----------------------------------------VNMSYGEPALLPDY-GRFVDLV--------------------TE-----------------------------------AVNK------------R----RL-----I--------------------------------------------------------------------------------------F---------------VSSAG-NS--------GP---------------ALTTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTTS-S---------------------------I---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MAAGAH---SVVEPPSEGLE-YTW-----S--S--------R-GPT-S----------------------------------------------------------------------D-----GDLGVCIS-----------------A-----P-------------G-----------------GA--------------------------------V------------------------------------------------------------------APVPTW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------RR--MLMNG------TSMASPSAC----G----------------------------------------------AIAL----LLSAMK-----AE--GIPVS-----------------------------------------------------------------PYS--------------V---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------STPV-GDLPEDKLTTGQGLMQVDKAYE-------- 981
 982 ------------------------------MPKH-EIGALRFLQD-------HPE-YDGR--------------------------G-V--KI--------------C--------------------IFD---------------------------T--------------GVDP-G------A-------------A---------G--------------------------------LQ-------------------ITTDGKP-KIIDII-DCTGSGDVDTSRVEKADV--D--------GCIAGASGRKLRLNPDW----KNPTGEWRVGCKHVYGLVSRGLVSRLK----------EERKRK-WEETQRGAIAEAVAALAKWVSFSGGKGKTQTMGPRAAGPRSSRGQEARFDKDTPASKLGSDP-----------------------EAKKERAELEGRVAALKARGDLAKSYEDPGPLIDAVVWHDG---------AAW-----------------------------------------------------------------------------------RAALDTSAL---------------------HPAGSGAGA----------------------------------------------------------------------LAAFTPLTNYADEHKYGTFSELD-------ACNFVLNILDGGRTLSVVVDC----------------GAHG-------TH-V-----------------------AGITA----AHFPD-------------------------------DP------------------------------GSN----GI--APG-A--QIISC---KIGDTRLGS------------ME--T------------GTG-------------------------------------V--------VRG--------------L-----------IA---AR--------------------Q-----H------G----------A----HL-----------------------------------------INMSYGEPTTTPNA-GRFIELA--------------------TE-----------------------------------LVRK------------H----GV-----I--------------------------------------------------------------------------------------F---------------VASAG-NA--------GP---------------ALTTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTSS-A---------------------------L---FG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LAAAGH---SVLEAPAEGLQ-YNW-----S--S--------R-GPT-S----------------------------------------------------------------------D-----GHTGVAFS-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------APVPQW-------------------------------------------------------------------------------------------------------------------------TQ-QVTSIRAGVAGPRR--QLMNG------TSMSSPNAC----G----------------------------------------------GIAL----LLSGLL-----AT--GGALA-----------------------------------------------------------------PHR--------------L---------------------RRAL-------ENT---------------------------------------------------------------------------------------------------ATPLGGGAPDAVLTYGRGLIQIDAAWE-------- 982
 983 -------------------------PKEGILPKA-ETEASKFIEE-------HPE-WDGR--------------------------G-I--KV--------------A--------------------IFD---------------------------T--------------GVDP-G------A-------------A---------G--------------------------------LL-------------------VTSDGRP-KMIDVV-DCTGSGDVDTSEVVELKE--GE-------TTITGLSGRTLNLGSR-----TCPSGKFHLGLKRAYELFPRPLVKRVK----------EERKES-FLVKQQEAVAAAQAAL--------------------------------REWEKSHKSPND-------------------------KEKKERKDLEQVVDALKEA---MEQYSDPGPAFDCVVYSDG---------ERW-----------------------------------------------------------------------------------RALIDFQE----------------------------SGD----------------------------------------------------------------------LQEVKALATFREEREFVTLSSVRGVRDHSVLLNVCVGIFQEGDLLSIVCEA----------------GSHG-------TH-V-----------------------AGIVA----ANFPD-------------------------------DP------------------------------KLN----GI--APG-A--QIVSC---KIGDSRLGS------------ME--T------------GTS-------------------------------------L--------IRA--------------L-----------KV---AK--------------------D-----N------G----------C----QL-----------------------------------------INLSYGESFVHDKS-GRVPELI--------------------NE-----------------------------------FVNK------------H----GI-----I--------------------------------------------------------------------------------------F---------------VCSAG-NN--------GP---------------ALSTVGA---------------------------------------------------------------------------------------------------------------------------------------PACMSS-S---------------------------F---IS---VGAFV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEVEY---SLRETLA-STN-YTW-----S--S--------R-GPS-P----------------------------------------------------------------------D-----GNLGVTIC-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------APVPTW-------------------------------------------------------------------------------------------------------------------------TL-Q-----------GK--QLMNG------TSMSSPNCC----G----------------------------------------------GLAL----ILSALL-----SG--AASWT-----------------------------------------------------------------PAS--------------I---------------------RRVI-------QNS---------------------------------------------------------------------------------------------------ALKV---EGIEPWALGPGLLQV------------- 983
 984 -----------------------PFPLIDLVPKK-ETNVRRFLEA-------YPE-YDGR--------------------------N-V--IV--------------G--------------------ILD---------------------------T--------------GVDP-G------A-------------H---------G--------------------------------LG-------------------TLPDGTTPKLLNVV-DCTGSGDVDVSTQVELQRHVNADADDGSDGNVHDANGNDTAVDDTPTPL-TTPLPQVRLGVKRAYELFPAKLRERVQ-----------ETRRQAFQAQLDRYVVDVRQQL--------------------------------AAWNVAHPKPPTSP-----------------------EEAKVRDDLQARLDVLLD----SEWNDDPGPLYDCVVFYDG---------TDY-----------------------------------------------------------------------------------QAVVDVHE----------------------------TGD----------------------------------------------------------------------LRNAQPFTSFAKSRQFGTLGTID-------QMNYAVQFYNQGTILSLVTDA----------------SPHG-------TH-V-----------------------AGITA----A---A-------------------------------EG------------------------------ERS----GV--APG-A--QLVSF---KIGDSRLGS------------ME--T------------GTS-------------------------------------L--------TRA--------------M-----------IE---AV--------------------R-----H------K----------C----DV-----------------------------------------INLSYGEGCAMPNH-GRFVELA--------------------EE-----------------------------------LVWK------------H----NV-----V--------------------------------------------------------------------------------------F---------------VSSAG-NN--------GP---------------AISTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTSS-A---------------------------C---IG---VSAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PA------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMKAGY---SMPYHT--GTT-YTW-----S--S--------V-GPT-A----------------------------------------------------------------------D-----GDNGVDVT-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------TSVSNW-------------------------------------------------------------------------------------------------------------------------CL-Q-----------KS--MLMNG------TSMSSPHAT----G----------------------------------------------CVAL----LISACK-----AE--GIPVS-----------------------------------------------------------------PAR--------------I---------------------RRAL-------QNS---------------------------------------------------------------------------------------------------AKRL---PNLSTLQQGWGMIQVDRAFD-------- 984
 985 ------------------------FPVEGLLPKN-ETEAAMFISS-------NPE-MDGR--------------------------G-T--VI--------------A--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LQ-------------------VTSHGLL-KIIHLI-DCTGAGDVPCSTVVEPTP--NADVTTSSLGTIVGLSGRTLTL-GNW----NCPTNKFRLGLKHSSDLYPGPLVDRLE----------KSSKEKTLISHH--ALLTQTEAL---------------------------------AVTADNSTATDD------------------------NAILTKNDQKARVEVLKDF---MKNHEDPGILMDCVVFHDG---------KTW-----------------------------------------------------------------------------------RAAIDVNE----------------------------TGD----------------------------------------------------------------------LTNVTTLASYSEEHQHLCFGDDS-------MLNYSVNIYDEGQMLSIVTLA----------------GSHG-------TH-V-----------------------AAISA----ANYPE-------------------------------DS------------------------------RLN----GI--APG-A--QIVSL---KIGDTRLGS------------ME--T------------GAG-------------------------------------L--------VRA--------------A-----------IE---LA--------------------R-----L------N----------I----DL-----------------------------------------ANISYGEAAAIPDT-GRFIELL-------------R------DE-----------------------------------VINK------------K----GC-----I--------------------------------------------------------------------------------------V---------------VASGG-NA--------GP---------------ALTTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTGS-A---------------------------V---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMDAEY---ALLDKVE-ERA-YTW-----S--S--------R-GPS-S----------------------------------------------------------------------D-----GDIGVDIF-----------------A-----P-------------G-----------------AA--------------------------------I------------------------------------------------------------------TSVPQY-------------------------------------------------------------------------------------------------------------------------TI-Q-----------RS--QLMNG------TSMSSPNCC----G----------------------------------------------CLAL----LLSGLK-----AK--QIPYT-----------------------------------------------------------------PYL--------------I---------------------KAAI-------QAT---------------------------------------------------------------------------------------------------GKDI-------KDPFGIRFVQVQKAWN-------- 985
 986 ------------------------FPVTSLVPKN-ETGALSFIRM-------YPE-YDGR--------------------------D-V--TI--------------A--------------------ILD---------------------------S--------------GVDP-R------A-------------K---------G--------------------------------LE-------------------QI-PGGDVKVIERF-DCSGCGDVDTSKTVTASP----D------GTIVGLSGRKLHLSSTMKSKNV-AGSEYRVGLKSVHDLSPSRIRERIL----------TDLKVKTWDDRHKVAVSEAAREL--------------------------------SDFEAKNP--STGLTG---------------------KDKLAKENLESTLEFLNTC---DKKFTDLKTSYDCVLFPTK---------EGW-----------------------------------------------------------------------------------MAVIDTTE----------------------------KGD----------------------------------------------------------------------LEDAVHVLEYTRSHQVVNL--DD-------FLSVSINVHDEGNVLEVVGVC----------------SSHG-------TH-V-----------------------ASIAS----GYHPD-------------------------------DP------------------------------ELN----GV--APA-A--KIVSL---TIGDGRLES------------ME--T------------GTA-------------------------------------L--------VRA--------------I-----------IK---VM--------------------ELCEAGR------K----------I----DV-----------------------------------------INMSYGEHGHWSNS-GRVGELM--------------------SE-----------------------------------LVNR------------Y----GV-----V--------------------------------------------------------------------------------------W---------------VASAG-NH--------GP---------------ALCTIGT---------------------------------------------------------------------------------------------------------------------------------------PPDISQPS---------------------------C---VG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEAEY---ALHQKLP-GNV-YTW-----S--S--------R-DPC-I----------------------------------------------------------------------D-----GGFGVTVC-----------------A-----P-------------G-----------------AA--------------------------------I------------------------------------------------------------------ASVPQF-------------------------------------------------------------------------------------------------------------------------TM-S-----------KA--QLMNG------TSMSAPHVA----G----------------------------------------------SVGL----LISGLK-----QK--SIPYT-----------------------------------------------------------------AFS--------------I---------------------KRAL-------WNT---------------------------------------------------------------------------------------------------ATKI---DYVDKFAQGNGLLNVGKAFD-------- 986
 987 -------------------GIVESFPTGALVPKA-ETGVLNFLQK-------YPE-YDGR--------------------------D-V--TI--------------A--------------------IFD---------------------------S--------------GVDP-R------A-------------T---------G--------------------------------LE-------------------TLCDGKTVKVIERY-DCSGCGDVDMKKKVTPDE----N------GNIKGLSGNSLKLSPELMALNTDPEKAVRVGLKSFSDLLPSKVRNNIV----------AQAKLKHWDKPHKTATANASRKI--------------------------------VEFESQNPGEASKLPW---------------------DKKILKENLDFELEMLNSY---EKVYGDIKTSYDCILFPTA---------DGW-----------------------------------------------------------------------------------LTIVDTTE----------------------------QGD----------------------------------------------------------------------LDQALRIGEYSRTHETRNV--DD-------FLSISVNVHDEGNVLEVVGMS----------------SPHG-------TH-V-----------------------SSIAS----GNH-S-------------------------------SR------------------------------DVD----GV--APN-A--KIVSM---TIGDGRLGS------------ME--T------------GTA-------------------------------------L--------VRA--------------M-----------TK---VM--------------------ELCRDGR------R----------I----DV-----------------------------------------INMSYGEHANWSNS-GRIGELM--------------------NE-----------------------------------VVNK------------Y----GV-----V--------------------------------------------------------------------------------------W---------------VASAG-NH--------GP---------------ALCTVGT---------------------------------------------------------------------------------------------------------------------------------------PPDISQPS---------------------------L---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMEAEY---AMREKLP-GNV-YTW-----T--S--------R-DPC-I----------------------------------------------------------------------D-----GGQGVTVC-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------ASVPQF-------------------------------------------------------------------------------------------------------------------------TM-S-----------KS--QLMNG------TSMAAPHVA----G----------------------------------------------AVAL----LISGLK-----QQ--NIEYS-----------------------------------------------------------------PYS--------------I---------------------KRAI-------SVT---------------------------------------------------------------------------------------------------ATKL---GYVDPFAQGHGLLNVEKAFE-------- 987
 988 ------------------------------LPKK-ETAAISYLNK-------FPS-YNGQ--------------------------G-T--VI--------------A--------------------IFD---------------------------S--------------GVDP-R------A-------------P---------G--------------------------------LQ-------------------VTSDGKR-KIIDCF-DGTGSGDV----TLVPAE--VKN------GTITGLSGRSLKIPDTW----TNPSGEYKIGYKSLYQLYPTALRERML----------KDFKENKWDPMHKKTLAETTKKF--------------------------------QAFESANPDSS----G---------------------AEKATKEDYEMQIEMLNTL---EKKFSNLGPCFDCVVFYDG---------QHW-----------------------------------------------------------------------------------RACLDTSY----------------------------EGQ----------------------------------------------------------------------LSQCKLMGIYRETFDVGTLSEED-------QLSYSINIYPEDNILEIVSMC----------------SSHG-------TH-V-----------------------ASIAS----ACFPD-------------------------------EP------------------------------EKN----GL--APG-A--QIVSI---AIGDNRLGS------------ME--T------------GTS-------------------------------------L--------VRA--------------M-----------IR---VI--------------------E--QTHY------K----------V----DV-----------------------------------------INMSYGEHAHWAHS-GRLGELM--------------------SD-----------------------------------VVNK------------Y----GI-----V--------------------------------------------------------------------------------------W---------------VVSGS-NH--------GP---------------ALSTVGT---------------------------------------------------------------------------------------------------------------------------------------PPAISSTS---------------------------L---IG---VGAYV------------------------------S--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMAAEY---SLREKLP-GMP-YTW-----S--S--------R-GPC-M----------------------------------------------------------------------D-----GSMGISIC-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------TSVPNF-------------------------------------------------------------------------------------------------------------------------ML-R-----------GS--QLMNG------TSMAAPHVT----G----------------------------------------------VVAL----LISGLK-----AR--EIPSS-----------------------------------------------------------------PFS--------------I---------------------KRAL-------EQT---------------------------------------------------------------------------------------------------AVFL---DGVEVFAQGHGLIQV------------- 988
 989 -------------------YSNKFYPVDGVVPKH-ETQAYEFLKK-------FPE-YDGR--------------------------G-V--TV--------------G--------------------ILD---------------------------T--------------GVDP-G------A-------------P---------G--------------------------------LS-------------------VTTTGLP-KFKNIV-DCTGAGDVDTSVEVAAADSNDY-------LTITGRSGRTLKLSKEW----KNPSKKWKVGCKLAYEFFPKDLRKRLQ-----------KLETEDMNKSNRKLLQDATDEY--------------------------------AKFKDKFPEAPLDK-----------------------DNLQTQKELEARIECLKQL---AEKFDNPGPLYDVVVFHDG---------EHW-----------------------------------------------------------------------------------RVVIDSDQ----------------------------TGD----------------------------------------------------------------------IYLHKPLADFNVAQEWSTFGSLD-------LLSYGVHVYDNGNITSIVAVS----------------GTHG-------TH-V-----------------------AGIIG----ANHPE-------------------------------TP------------------------------ELN----GA--APG-C--QLVSL---MIGDGRLDS------------LE--T------------SHA-------------------------------------F--------SRA--------------C-----------SE---II--------------------K-----N------E----------V----DI-----------------------------------------INISFGEDAGIPNK-GRVIELL-------------R------DE-----------------------------------LAGK------------R----NV-----V--------------------------------------------------------------------------------------I---------------VSSAG-NN--------GP---------------AYTTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTTF-D---------------------------V---IS---VGAYV------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMQAQY---NLLSTVH-DTP-YTW-----C--S--------R-GPT-L----------------------------------------------------------------------D-----GDTGVSIY-----------------A-----P-------------G-----------------GA--------------------------------I------------------------------------------------------------------TSVPPY-------------------------------------------------------------------------------------------------------------------------SL-Q-----------NS--QLMNG------TSMSSPSAC----G----------------------------------------------GISL----ILSALK-----AQ--KKPYT-----------------------------------------------------------------AAA--------------I---------------------KKAV-------MYT---------------------------------------------------------------------------------------------------SK--------------------------------- 989
 990 --------------------IVPQQPLDALLLNKTDTEQEMFLTK-------YPT-YDGR--------------------------D-I--LI--------------A--------------------ILD---------------------------T--------------GVDP-S------L-------------P---------G--------------------------------MQ-------------------VTTTGER-KVFDVI-DCSGAGDVDTSATRTVKD-----------KTIEGISGRKLTIPDKW----TNPTGVYHVGLKPIFELYTKGVKSRVV----------SERKEDVVGPSHNLAAAEALKEL--------------------------------VAHEKDVGGTSEKT-----------------------SDKWTREDLACKVDFLKSM----ASVSDVGPVADVITWHDG---------DVW-----------------------------------------------------------------------------------RVCIDTSF----------------------------RGR----------------------------------------------------------------------LGMCNVLGTFRETGDYACLTDKD-------SVVYTVRVSPDGNLTEIVVPS----------------GAHG-------SH-V-----------------------AGIAA----ANYPD-------------------------------NP------------------------------QKN----GL--APG-A--KILSL---NIGDHRLAA------------ME--T------------GQA-------------------------------------M--------TRA--------------F-----------NM---CA--------------------E-----L------N----------V----DV-----------------------------------------INMSFGEGTHLPDV-GRVVEEA--------------------RR-----------------------------------LIDR------------K----DV-----I--------------------------------------------------------------------------------------Y---------------VCSAG-NQ--------GP---------------ALSTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTTT-G---------------------------V---IG---IGAYL------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADTLY---GVYKPVD-NNI-YPW-----S--S--------R-GPC-Q----------------------------------------------------------------------D-----GKLGVSLV-----------------A-----P-------------A-----------------AA--------------------------------F------------------------------------------------------------------AGVPQY-------------------------------------------------------------------------------------------------------------------------CR-Q-----------SM--QMMNG------TSMSSPNAA----G----------------------------------------------NVAC----MLSGLK-----QL--DLKWT-----------------------------------------------------------------PYT--------------V---------------------RMAL-------ENT---------------------------------------------------------------------------------------------------AFPL---PNVDAFSQGQGMIKIATAFD-------- 990
 991 --------------------IVPQQPLDALLLNKTDTEQEIFLTK-------YPN-YDGR--------------------------D-I--LI--------------A--------------------ILD---------------------------T--------------GVDP-S------L-------------P---------G--------------------------------MQ-------------------VTTTGER-KMFDVI-DCSGAGDVDTSITRTVKD-----------GVIEGISGRKLAIPEKW----KCPTGQYHVGLKPIFELYTKGVKSRVI----------SERKEDVVGPSHNIAASEALKQL--------------------------------TEHEKVVGGTSEKT-----------------------SDKWAREDFACKVDFLKSM----ASVADVGPVADVVTWHDG---------EMW-----------------------------------------------------------------------------------RVCIDTSF----------------------------RGR----------------------------------------------------------------------LGLGNVLGTFRETGDYAYLTNKD-------SVVYTVRVSPDGNLTEIVVPS----------------GAHG-------SH-V-----------------------AGIAA----ANYPD-------------------------------NP------------------------------QKN----GL--APG-A--KILSL---NIGDHRLGA------------ME--T------------GQA-------------------------------------M--------TRA--------------F-----------NM---CA--------------------E-----L------N----------V----DI-----------------------------------------INMSFGEGTHLPDV-GRVIEEA--------------------RR-----------------------------------LINR------------R----GV-----I--------------------------------------------------------------------------------------Y---------------VCSAG-NQ--------GP---------------ALSTVGA---------------------------------------------------------------------------------------------------------------------------------------PGGTTT-G---------------------------V---IG---IGAYL------------------------------T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SE------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SADTLY---GVYKPVE-SSI-YPW-----S--S--------R-GPC-Q----------------------------------------------------------------------D-----GKLGVSLV-----------------A-----P-------------A-----------------AA--------------------------------F------------------------------------------------------------------AGVPQY-------------------------------------------------------------------------------------------------------------------------CR-Q-----------SM--QMMNG------TSMSSPNAA----G----------------------------------------------NVAC----MLSGLK-----QN--NLKWT-----------------------------------------------------------------PYT--------------V---------------------RMAL-------ENT---------------------------------------------------------------------------------------------------AYML---PHIESFSQGQGMIKIATAYE-------- 991
 992 --------------------------FSSLLPKK-QINSDIFLND-------HAK-CNGC--------------------------V-T--RI--------------A--------------------VWD---------------------------T--------------GIDP-T------A-------------A---------G--------------------------------LQ-------------------ITPDGNR-KIVDMI-DASGSGDVKMKYKRFIDQKH---------RIIETLTGRKVEIPSHW----NPPDGIIRIGVKPASELFPKLLMQRLR----------GENRDNFWRPCIKRIAANLAYDL--------------------------------TE-----------------------------------AEEYLNQNLMSNHNGNKSW---YQHYSPLEIIYDCFVFHDG---------NEW-----------------------------------------------------------------------------------VACIDTSPY---------------------NP----NTK----------------------------------------------------------------------LSDLPLLRDYTVNHQYASFGEQT-------QLYYTVKIFDNGKLLQIVTNN----------------SSHG-------TH-V-----------------------AAIAS----AYFPN-------------------------------HH------------SETSSPSSGTVTNSTMLCDRD----GV--APG-A--QIVSI---KISDSRLGP------------ME--T------------GIS-------------------------------------L--------LRA--------------I-----------RW---TI--------------------E-----L------K----------C----DI-----------------------------------------VNYSFGEQAIWPNI-GRISKYL--------------------NR-----------------------------------MIHK------------Y----GI-----I--------------------------------------------------------------------------------------M---------------VASGG-NN--------GP---------------SLGSLSC---------------------------------------------------------------------------------------------------------------------------------------PGGTVQ-G---------------------------V---IG---VAPLV------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------PD------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MMHYLYCQPSDSSENAKPTA-YNW-----G--S--------R-GPA-F----------------------------------------------------------------------D-----GALGICVA-----------------A-----P-------------G-----------------GA--------------------------------N------------------------------------------------------------------TSIASW-------------------------------------------------------------------------------------------------------------------------QL-K-----------PA--SVLSG------SSMSAPMVT----G----------------------------------------------GISL----ILSGLRHRYTCSESQRLKIP-----------------------------------------------------------------SSL--------------I---------------------YRCL-------MNT---------------------------------------------------------------------------------------------------CKSF---EHLSYLDQGYGLMQVDRAF--------- 992
 993 --------------------------------------FLALKSTGVEDFIKQHPEYDGR--------------------------GTI--II-----------------------------------VLD---------------------------T--------------GVDMGIDGLVKTS-------------TGQVKVIDVQD--------------------------------F--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TGEGDMQFYPADKRTDDGKTILENLDKKFSVKADLEKLIPSADKNYFIGAFPEKHLINSNSGSADLNGNGSTDDVYYFIAYKTTDEYWVVYFDLNGNGDVSDERPIRNYKENFDAFSVERAKGLAPFTMALNIFPEENKVVFFFDDGSHG-------TH-C-----------------------AGIAAGFNIGEVGL---------------------------------------------------------------------NGV--APG-A--NIIAL---KI-----------------GHNNFPG------------GAT-------------------------------------VNESMKKAYVYA--------------------------DK----------------------------------------------ISRERKEPCI-----------------------------------------VSMSYG----------------------------------------------------------------IGSEIEDHSEMENFLAKLLKENPYLY--------------------------------------------------------------------------------------------------V---------------SVSNG-NEG----------------------------------------------------------------------------------------------------------------------------------------------------------------------PGISSS---------------------GLPASSNYV---FS---SG--A------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VLAKEVARDNYGNELPNDVILHF-----S--S--------RGG--------------------------------------------------------------------------EVSKPDV------V-----------------S-----P-------------G-----------------AA---------------------------------------------------------------------------------------------------TS----------------------------------------------------------------------------------------------------------------------------------------TVPNFTPGDKFWG------TSMACPYSA----G---------------------------V------------------MSLI----------------------------------------------------------------------------------------------------------LSAAQKEFSDIKIPSQLLYKIIRESA-----------------------------------------------------------------------------------------------------------------TYWNQYTVLDQGGGFINV------------- 993
 994 --------------------PSPQTPAENPYLPTADTGAVAFTKK-------NPT-YDGR--------------------------G-I--TI--------------G--------------------VLD---------------------------S--------------GIDL-E------H-------------P---------A--------------------------------L---------------------A----------------TTTTGERKISNWITATDPLLESDPTWRVMLNRVSGETATFRGANWKLPHRDDAQYSIDIFRESSSARSEFKGDI------------------------------------------------------------------------------------------------------DRNGKTADSWGVL------YDYQT--------HDIWV------------DT-----------------------------------------------------------------------------------------D---G---------------------DHDFTNNTP----------------------------------------------------------------------MRPYAEKNQVGHFGKDNPSTRVQENVPFVVEYRTNVDLTPIGHAGTTADVINIGTVSS----------AHG-------TH-V-----------------------AGIAA----ANM-----------------------------------------------PGWKMQ-------------------GA--APG-A--KVVSA---EA---CVYA----------G-GC--T------------SVA-------------------------------------L--------TEG-------------MI-----------EL---VA--------------------N-----Q------R----------V----DI-----------------------------------------VNMSIGGLPA---L-NDG---N--------------------N---------------------------TRSA-----LYNRII--------DEY----GV-----Q--------------------------------------------------------------------------------------I---------------FISAG-NS--------GA--------GTNTIGD----------------------------------------------------------------------------------------------------------------------------------------------P-S--V-A----TD---------------------A---VS---VA--A------------------------------G-----------------------------A----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKDTWLANYGAKAKE-------------------------------------------------------------------------------------EY-------W-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-QNY-----S--S--------R-G---P--------------------RE------DGG-F---K--------------------P------------N-----I------M-----------------A-----P-------------G-----------------SA--------------------------------I-------------------------------------------------------------------S-AVP-----------------------------------------------------------------------------------------------MFM-DPEDIPQVSYKLPV--------GL-SM----------------FNG------TSMASPQAT----G---------------------------A------------------AA-L----LLSAARQ-------NDLPVT-----------------------------------------------------------------PAQ--------------L---------------------RASL-------EST------------------------TRF------------------------------------------------------------------------IPG------LEPTAQGNGLIRI------------- 994
 995 ----------------------------------------------------------DLKDNIIEKKTDNIDGINN---IKSS----------------------------------------------D---------------------------N--------------INSS-D------N-------------I---------K--------------------------------SSDNINSSDNIKSSDNIKSSDNNNVHTMLRNKLYLKKKKECSNY--NTSN--DGH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TF-I-----------------------AGIIA------GNS--------------------------------------------------------------PKGKKGIKGISKKAK----LII----CKA-------------------LN---------------NN-------------------------------NAGYISDI--------LECFNFCAKKK------A-------------------------------------------------------------------RI-----------------------------------------INASFA------STTHYPSLFQ-------------ALKE-LQDK--------------------------------------------------------DI-----L--------------------------------------------------------------------------------------V---------------ISSSG-NCSSN--SK----------------------------------------------------------------------------------------------------------------------------------------------------------------CKQAFQECNLNIQKLYP---------AAYSADLNNI---IS---VSNII---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QQS-----------------------------------------------------------NGN------------------------IVLSPDSCY-----S-----------P----------------------------------------------------------------------------------------------------------------------NYVHLAAPGGNIISTF----------P---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NNKYAISSG------TSFSASVIT----G---------------------------L------------------ASLV----LS------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ 995
 996 --------------------------------------------NGDVKNLFSKDQ-----WYIELLEINRAWN-----QMRKMRRKPV--KV--------------C--------------------IVD---------------------------T--------------GIDY-H------H-------------D---------A--------------------------------LRDAIEL--NEMELNGIQGVDDDD--NGLIDDIYG------ANFVDNNMDPMDLH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TS-L-----------------------AGIIA----AKYKN-----------------------------------------------------------------PQDIAGINTYAR----LIP----CKA-------------------FD---------------SN-------------------------------LEGYLSDI--------LQCIDYCLARG------A-------------------------------------------------------------------MV-----------------------------------------QNHSWT------HHKESDALKS-------------AFAV-AEAR--------------------------------------------------------NV-----L--------------------------------------------------------------------------------------M---------------VVSVG-NVYYQ--HG---------------------------------------------------------------------------------------------------------------------------------------------------------------------KRRNIDNHVVVP---------AMYSKYFLNV---LT---VSGMQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------VTS-----------------------------------------------------------EATIRERVERCKLTKPDASCEPSKDLQYELYHKSQF-----G-----------L----------------------------------------------------------------------------------------------------------------------SLSQLVAPAYSIHTLW--------KNN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SKVIAE--G------VSMATAIVT----G---------------------------V------------------ASLL----LS-----------------------------------------------------------------------------------IDMKFL----QLTSVSVT------------------HYIRHNI-------MPLPALKNKVRWGGYVNCRATVISMV--------------------------------------------------------------------------------------------------------------- 996
 997 ----------------------------------------------------------------------------------------I--KI--------------A--------------------ILD---------------------------S--------------GCDY-L------H-------------S---------E--------------------------------LNDNILINKSKSMI----------PY-----EENIEDYN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------ISSII----GKKNV---------------------------------------------------------------------KGI--APA-V--SILSY---KIVDKNGYGE-LRWTINAIKLAIQEN----------------------------------------------------V---------------------------------------------------------------------------------------------HI-----------------------------------------INIS--Y---------TSN------------------------------------------------------------KIDDIDMIYEYKEVVEEAINKGI-----Y--------------------------------------------------------------------------------------V---------------ICAAG-NECKEIKQGSENL-PIYLAEGI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------V---IA--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--D--------YKGELSSFSNYGVGIDFSMPSG------G------------------------------------------------------FSQGFPSQYGLVIVAKPRSMARLHLEDQYQVP-------------K---------------------------------------------------D------------------------------------------------------------------YT--------------------------------------------------------------------------------------------------------------------------------------LT-----------MG------TSISSALFS----G---------------------------T------------------IALL----LSRY-----------------------------------------------------------------------------------------------------------------------------------------------------YRLY------------------------------------------------------------------------------------------------------------------- 997
 998 -----------------------------FSWNSYKVTNGYRLYDLQVGSPL------------------------------------I--KI--------------A--------------------VID---------------------------S--------------GYDP-N------H-------------S---------E--------------------------------ITGNIDKKKSCSFV----------DY-----ENFNEDLY---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------ISVIV----GKNQV---------------------------------------------------------------------KGV--APG-I--TIISY---KVLDRNGFGK-IEWVIHAILKAIEDC----------------------------------------------------V---------------------------------------------------------------------------------------------HI-----------------------------------------INLSHVF---------TMF------------------------------------------------------------GLGNKGAFNKLQQAIDKARKKGI-----I--------------------------------------------------------------------------------------I---------------VGAAG-NQGVLLDMKSTSLYPT--IKGI------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NY---VT--S----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T--N--------KNNYTSSYANIGSIIRFAAPSG------E------------------------------------------------------LDET-NNVTDLIIVAHPTNFPKTKFEKAIGLP-------------D---------------------------------------------------F------------------------------------------------------------------YT--------------------------------------------------------------------------------------------------------------------------------------VT-----------CG------TSISAAMFS----S---------------------------L------------------IALV----LTEYLIC-------KQIHLS----------------------------------------------------------------------------------E------------------KEILNII-------QKNSSRVKDQNSIFEINAYSVI------------------------------------------------------------------------------------------------------------------- 998
 999 ------------------------------------------------------------------------MTNSDYINYTYDDRDFFEKIL-----------------------------------FID---------------------------S--------------GCDY-N------HSELKNNIDLKNCKSFVDNNLNDYT--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TQ-I-----------------------ISVLT----GKIYL---------------------------------------------------------------------RGL--IPN-A--SIVVY---KVTDYRGKT---------------------------------------------------------------------SIEKIYKALSQG-----------------------------------------------------------------------------VKKGFKV-----------------------------------------INVSFSG------------------------------------------------------------------------AIDSIFYTKKFQEIIDEARIKNI-----I-------------------------------------------ICWSPMNNDNRLNNHKNNTNLIPNDFKNLFQIGSINRLNQISNL----------------VCNE-NEIDFFAPGGDLVSETIPIEESFILLANTQLLCK------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LSDYYIG------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------I------------------------------PK------------G-----------------YT--------------------------------I----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NMG------NSIATSYAS----G---------------------------C------------------FMII-----------------------------------------------------------------------------------------ISKFKRKYKYYPSINEVLKLISKYSNSEINLIKITRSVVENALI----------------------------------------------------------------------------------------------------------------------------------------------- 999
1000 --------------------------------------------------LPNSKAVLES----------------------------E--RI--------------A--------------------IFD---------------------------G--------------GLGTAD-LSNWVTEY-VYPDTKETSGL---------L--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------NE-V-----------------------TSTFLFGRVEENAP--------------------------------------------------------------------------SFKRPFMNVDHY---RVLSPTSGD-----------------------------NGN-------------------------------------WDLFDVLKKIQS-------------------------------VL--------------------------------------------DSGDYKF-----------------------------------------ANLSIGPHLPIGDD-----------------------------------------------------------------EVHVWTAVLDQICAKHG----IL-----L--------------------------------------------------------------------------------------T----------------VAVG-NDGNEDGDA--ARIQ----------------------------------------------------------------------------------------------------------------------------------------------------------PPSDMVNA-------------------------------LA---IG--A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ADRSGEK-WGRAPY-----S-----------CIGPGRS-----------------------------------------------------------------------------------------------------------P-------------G-----------------FVKPDGVIFGGSDDEPFYTYN--------PLLGSI------------------------------------------------------------------VG--------------------------------------------------------------------------------------------------------------------------------------------------VQG------TSYASPLALRTAAG----------------------------------------------VAALSGTPLN----------------------------------------------------------------------------------------------------T------------------IALKALL-------VHHAETSRKYSREHIGWGR----------------------------------------------------------------------------------------------------------------------1000
1001 --------------------------------------ISRSVIQTSNLSLPSEGAVNPH----------------------------I--KV--------------A--------------------IFD---------------------------G--------------GLGIDD-FNPWVTEY-TFNGNASTNAK---------L--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------QD-V-----------------------TSTVLFGVLGSETE--------------------------------------------------------------------------KLSVPYCNIDHY---RVLD-SNVN-----------------------------NSD-------------------------------------VDLFDVLIRIKS-------------------------------VL--------------------------------------------EQKKYDY-----------------------------------------INLSLGPRLPVDDD-----------------------------------------------------------------DVHVWTSTLEEILASGE----TL-----C--------------------------------------------------------------------------------------T----------------VAVG-NDGQLPAKL--NRIQ----------------------------------------------------------------------------------------------------------------------------------------------------------PPADLVNG-------------------------------LS---VG--A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ATSLSDS-WERCSY-----S-----------CIGPGRS-----------------------------------------------------------------------------------------------------------P-------------G-----------------FVKPDGVAFGGHSDEPFQVYS--------PMVNGL------------------------------------------------------------------AA--------------------------------------------------------------------------------------------------------------------------------------------------LR-------TSFSAPLVLRQAIA----------------------------------------------LSASLNYNIT----------------------------------------------------------------------------------------------------P------------------LTAKALL-------IHHAE-SNNINRAEVGWGR----------------------------------------------------------------------------------------------------------------------1001
1002 -----------------------------VPRLRGIRPIQRNYGPLAQCKLPAEGPVSSE----------------------------I--KV--------------A--------------------ILD---------------------------G--------------GLPSEHAISPWLKSYRVLDDHAEDDPD---------G--------------------------------L-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EHG-------LA-V-----------------------SSAFLFGPISNKSE--------------------------------------------------------------------------A-KRPYSYIDNL---RVLDNKTCQ-----------------------------EDP-------------------------------------LELYRTLGFIEE-------------------------------VL--------------------------------------------LSRQYQF-----------------------------------------INLSLGPDLPIEDT-----------------------------------------------------------------EVHAWTSVIDDLLSDGE----TL-----M--------------------------------------------------------------------------------------T----------------VAVG-NNGEMDRKSGNARIQ----------------------------------------------------------------------------------------------------------------------------------------------------------VPADCVNA-------------------------------LA---VG--A---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CDTVNDTEWKRAPY-----S-----------AIGPGRS-----------------------------------------------------------------------------------------------------------P-------------G-----------------VMKPDLVAFGGDTDEYFHVLGKGKKPVIIPQLG---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSFASPYALRAAVG----------------------------------------------VRAILGNDLS----------------------------------------------------------------------------------------------------L------------------LAIKALL-------IHA---SKQLD------------------------------------------------------------------------------------------------------------------------------1002
1003 ----------------------------------------------------------LEFRSLRTGNTCETKDENIILSGNKFVPTAT---L--------------G--------------------VFD---------------------------G--------------GVES-N------N-------------S---------I--------------------------------IKRYVVEH---------------------------------NLTSKNKEIE--CL-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KHG-------TM-V-----------------------TSAAL-----------------------------------------------------------------------------FGDLKNMTS----NKLTIPTIKV-------------------ES---------------FR--V------------LPL---------EDESDYVDLYEV--------IDKIEDIVPKR-PD---I-------------------------------------------------------------------KV-----------------------------------------FNLSLG-PVGPIQDDTITRFTY-------------ALDRLSKDG--------------------------------------------------------ER-----I--------------------------------------------------------------------------------------F---------------AIAVG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DGSY--------GEELGRIQAPSDSVNN---IA---VGAYE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNNKTI---------------------------------------------------------------------------------------QRTEY-----S-----------CMGDG-------------------------------------------------------------------------------------------------------------REGAKVKPDVVEYGGSINN--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QMHFISPVEGEKLFDCG------TSFSTPVVA----R---------------------------K------------------LVEI----L----------------------------------------------------------------------------------------------EYSSIRYP------------------LTAKAIL-------IHTS----NHPKNKPDKHLGYGVV-----------------------------------------------------------------------------------------------------------------1003
1004 ----------------------------------------------------------------------------------KPKNEPV---I--------------G--------------------VID---------------------------T--------------MFDT-N------V-----------------------Y--------------------------------FSEWVEFK---------------------------------NMLEKDIPLDANDY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TE-V-----------------------SSIIV-----------------------------------------------------------------------------DGA-TINPN----LDDGCGRFRV-------------------RH---------------FG---------------------------VAKSGSFSSFIV--------LKTIKEIVEKN-KD---I-------------------------------------------------------------------KV-----------------------------------------WNLSLG-SVMEINSNFISPEAA-------------ILDKIQFEN--------------------------------------------------------DI-----I--------------------------------------------------------------------------------------F---------------VVAGT-N---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPK--NSNVKKIGAPADSINS---MV---VNSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------TSN------------------------------------------------------------------------------------------KPVDY-----S-----------REGLV-------------------------------------------------------------------------------------------------------------LSFF-NKPDISYYGGDSEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIRTCSP-YGE-TMVAG------TSFAAPWIS----R---------------------------K------------------LAYL----IN-----------------------------------------------------------------------------------IL--------GLSK----------------------ETAKALI-------IDSATGWNKQVYSS--SLIGYGV------------------------------------------------------------------------------------------------------------------1004
1005 --------------------------------------------------------------------------KDYTISIPKPKNEPV---I--------------G--------------------VID---------------------------T--------------MFDT-N------V-----------------------Y--------------------------------FSEWVEFK---------------------------------NMLEKDIPLDANDY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TE-V-----------------------SSIIV-----------------------------------------------------------------------------DGA-TINPN----LDDGCGRFRV-------------------RH---------------FG---------------------------VAKSGSFSSFIV--------LKAIKEIVEKN-KD---I-------------------------------------------------------------------KV-----------------------------------------WNLSLG-SAMEINSNFVSPEAA-------------ILDKIQFEN--------------------------------------------------------DI-----I--------------------------------------------------------------------------------------F---------------VVAGT-N---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KPK--SSNVKKIGAPADSINS---IV---VNSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------ISN------------------------------------------------------------------------------------------KPVDY-----S-----------REGLV-------------------------------------------------------------------------------------------------------------LSFF-NKPDISYYGGDSEQ--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RIRTCSP-YGE-TMVAG------TSFAAPWIS----R---------------------------K------------------LAYL----IN-----------------------------------------------------------------------------------IL--------GLSK----------------------ETAKALI-------IDSATGWNKQVYSS--SLIGYGV------------------------------------------------------------------------------------------------------------------1005
1006 -----------------------------------TVYLDENQVEILFEKAPYLVSMATVDLSSLSPDDFINEYQTKMVTIPSPTIEPT---I--------------G--------------------VID---------------------------T--------------LFDE-S------V-----------------------Y--------------------------------FSDWVEYH---------------------------------DMVSEDIPKNPKDY-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TA-V-----------------------SSIIV-----------------------------------------------------------------------------DGA-RLNPW----LDDGCGRFKV-------------------RH---------------FG---------------------------VAVGAEFSSFSI--------IKKIKSIVVNN-SN---I-------------------------------------------------------------------KV-----------------------------------------WNISLG-SNQEINDNFISAEAA-------------TLDKIQFDN--------------------------------------------------------NV-----I--------------------------------------------------------------------------------------F---------------VVAGT-N---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KP---SADIVKIGSPADSVNS---IV---VNSVS---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KNG------------------------------------------------------------------------------------------LSTKY-----A-----------RKGLV-------------------------------------------------------------------------------------------------------------LSFF-AKPDVSYYGGSEEE--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YIRVCEP-LGA-ASVAG------TSYAAPWIA----R---------------------------K------------------LSYL----ID-----------------------------------------------------------------------------------VL--------GLNR----------------------EIAKAMI-------IDAARGWDEKPTPEEVALYGHGVVPIHINDIIQTKDDEIKFVVSDISEKWNTYNYDFPVPLKDNKYPYIAK------------------------------------------------------------------1006
1007 ---------------------------------------------------------------------------------------PI---I--------------G--------------------ILD---------------------------S--------------GIAD-I------T-----------------------Q--------------------------------LLPWKYGK---------------------------------RYTNYPSDVL--NV-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------AGIIN-----------------------------------------------------------------------------FGD-IFEGK----EYTGTSGFKI-------------------LD---------------AA--V------------VPDQRKE-----NITEG-----DL--------INNIREVVDMHGDD---V-------------------------------------------------------------------KI-----------------------------------------WNLSVG-TRYDFKDTEFSNFGI-------------ALDSIQDEY--------------------------------------------------------DV-----L--------------------------------------------------------------------------------------I---------------VKSAG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CRNFLEGKP---TNK---ITGGADSIRS---LT---VGSIA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QSK---------------------------------------------------------------------------------NEFDLAEYNHPSPF-----S-----------RIGPG-------------------------------------------------------------------------------------------------------------PVNI-IKPELVHYGGNCGI-----------KD-G--------------------------------E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------IIPNGVSSLST-TGELTTKTG------TSYSTPRVA----A---------------------------M------------------AADL----NS-----------------------------------------------------------------------------------KLNE------DFDS----------------------VLLKALL-------THSA---------------KYPVEVELPMN-----------------------------------------------------------------------------------------------------------1007
1008 ---------------------------------------------------------PMPTYSIDLDFFNIDENPIVRV-PKEGTDYVT---V--------------G--------------------VLD---------------------------S--------------GISN-I------K-----------------------S--------------------------------LEPWLVGE---------------------------------RQTFYPENLI--DS-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TF-V-----------------------AGVIL-----------------------------------------------------------------------------YGD-ELEDK----EYTGLKGCRI-------------------FD---------------GN--V------------FPDLKKE-----TIYED-----EL--------INNIREIIKNHYKE---V-------------------------------------------------------------------KV-----------------------------------------WNLSGG-LTEEIDENEFSDFAK-------------ALDDIQDTY--------------------------------------------------------GV-----I--------------------------------------------------------------------------------------I---------------CKSAG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------CTNFMNRKP---KRH---IAKSADSVRS---IV---VGSIA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HKK---------------------------------------------------------------------------------NLESKIDVDFPSPF-----T-----------RVGRG-------------------------------------------------------------------------------------------------------------PSSI-IKPDVVHYGGNAGI-----------DNKG--------------------------------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------LVMNGVKSFDV-NGNISRNIG------TSFSTPRIT----S---------------------------I------------------LAGL----QL-----------------------------------------------------------------------------------EIDE------EFDP----------------------LLLKALL-------IHSA-------------------------------------------------------------------------------------------------------------------------------------1008
1009 --------------------------------------------------------------------------------FDPDKQYPK---I--------------G--------------------ILD---------------------------S--------------GIER-N------E-----------------------Y--------------------------------NEDWII-N---------------------------------RERFYLDEDI--DT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------TF-V-----------------------SGIVL-----------------------------------------------------------------------------YGD-QLEGK----QYTGINGCRI-------------------LD--------------------------------VPILTSE-----T-DED-----EL--------ISNIKRAIANN-RD---I-------------------------------------------------------------------KI-----------------------------------------WNLSVS-VTREADNESFSDIAI-------------ALDQIQDEF--------------------------------------------------------DV-----I--------------------------------------------------------------------------------------I---------------CKSAG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------STAFLEGFP---KEK---IHTPAESVRA---VT---VGSIQ---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QED---------------------------------------------------------------------------------DGVGYAKKDEPTPY-----T-----------RIGRG-------------------------------------------------------------------------------------------------------------PAKI-IKPEVVHYGGDVWK-----------DPNG--------------------------------E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FVMKGVKSLTP-TGDMKSDCG------TSFSTPRIA----A---------------------------I------------------LAGL----EN-----------------------------------------------------------------------------------EIEE------EFDA----------------------LTLKTLL-------VHSA---------------NYGTCTEMNPAEKLEQIGFG--------------------------------------------------------------------------------------------------1009
1010 ----------------------------------------------------------------------------------------T---L--------------G--------------------VID---------------------------N--------------GIAH-I------K-----------------------Y--------------------------------LDPWIK-R---------------------------------VHTKFLKKDT--SA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TF-V-----------------------SGIAL-----------------------------------------------------------------------------YGD-KLENK----EIVKNEGFYL-------------------LD---------------AT--V---------------LSAT-----TIEED-----DL--------LQNIISAIKENYKK---V-------------------------------------------------------------------KI-----------------------------------------WNLSLS-VKLAIEEDTFSDFGV-------------VLDHLQKTY--------------------------------------------------------GV-----L--------------------------------------------------------------------------------------I---------------FKSAG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNFMKKLP---KGK---LYHGSDSLLS---IV---VGAIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DER------------------------------------------------------------------------------------------YASNY-----S-----------RVGLG-------------------------------------------------------------------------------------------------------------PKGT-VKPDLASYGGELLL-----------GDNG--------------------------------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIMQGVKSFSR-NGNIASSSG------TSFATARIS----S---------------------------L------------------ATII----YQ-----------------------------------------------------------------------------------NICKDFKDFSDFNP----------------------TFLKALI-------IHSA-------------------------------------------------------------------------------------------------------------------------------------1010
1011 ---------------------------------------------------------------------DIEGEVPVIY-PEENKNYVT---L--------------G--------------------VID---------------------------N--------------GIAH-I------K-----------------------Y--------------------------------LAPWIK-R---------------------------------VHTRFLKKDT--SA-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------THG-------TF-V-----------------------SGIAL-----------------------------------------------------------------------------YGD-KLENR----EMVKNEGFYL-------------------LD---------------AT--V---------------LSAT-----TIEED-----DL--------LQNITLAIKENHKK---V-------------------------------------------------------------------KI-----------------------------------------WNLSLS-VKLAIEEDTFSDFGV-------------VLDHLQKTY--------------------------------------------------------GV-----L--------------------------------------------------------------------------------------I---------------CKSAG-N--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GGNFMKKLP---KGK---LYHGSDSLLS---VV---VGAIN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NER------------------------------------------------------------------------------------------YASNY-----S-----------RIGLG-------------------------------------------------------------------------------------------------------------PRGT-IKPDVASYGGELLL-----------GDNG--------------------------------E----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------MIMKGVKSFSR-NGNIASSSG------TSFATARIS----S---------------------------L------------------ATII----YQ-----------------------------------------------------------------------------------NICKDFKDFSDFNS----------------------TLLKALI-------IHSAKNTDRNLSIEEIGYGIPATSTEILSYFKNENVKIFNGVMEKNQEID---------------------------------------------------------------------------------------1011
1012 -------------------------------------------------------VDLPPKYGLERTLLYIDIQEIPDP-PPPPDTAPV---I--------------G--------------------ILD---------------------------S--------------GIVS-T------H-----------------------N--------------------------------LLKSAVGD---------------------------------VQSFLPDYPPQDGT-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TL-V-----------------------AGIAL-----------------------------------------------------------------------------YGDVEEKLR----NRQFIPVFWI-------------------VS---------------GR---------------------------ILDDKNENRTGF--------LEKHIEEAVRYFYEHYGC-------------------------------------------------------------------RI-----------------------------------------FNLSLGDRRKPYLGGHLRGLAY-------------TLDKLAREL--------------------------------------------------------GV-----L--------------------------------------------------------------------------------------F---------------IVSTG-NVLPS--QH-----------------------------------------------------------------------------------------------------------------------------------------------------------------------DGRSWKENYPHYLFNDEWAILDPAPALNA---IT---VGSIA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RWDQTYN---------------------------------------------------------------------SQRYRHDPAEIPIARRNQPSPF-----T-----------RHGPS-------------------------------------------------------------------------------------------------------------IGGA-IKPELVAYGGNWAINVRAGSFNVLNKSQG--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GELSFNKDFST-NGPFAENSG------TSFSAPHVT----H---------------------------L------------------AGLI----LS-----------------------------------------------------------------------------------EYS-------EASH----------------------NLLRALL-------IAHADTLEEWKDLF-----------------EEEKDILKVCGYGLVDLEAL--------------------------------------------------------------------------------------1012
1013 -------------------------------------------------------VDLPPSSGISYQQINRDINTLPEHLISPAVNAAR---V--------------C--------------------ILD---------------------------S--------------GINT-N------H-----------------------P--------------------------------LLSAAIAE---------------------------------SASFIPNQDAFDQE-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-V-----------------------ASIAL-----------------------------------------------------------------------------YGDVEACNQ----SNFWQPQLWL-------------------YN---------------GK---------------------------VLNERAEFNAET--------IESTLTAAVAYFTD-LGC-------------------------------------------------------------------RI-----------------------------------------FNLSLGNANAPYDGKHIRGMAY-------------LLDTLARQY--------------------------------------------------------NV-----L--------------------------------------------------------------------------------------F---------------VVSAG-NFAGS--DD----------------------------------------------------------------------------------------------------------------------------------------------------------------P----PVPQNSWRDEYPDYLLHEDSVIIDPAPALNV---LT---VGSVA---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHNATLD---------------------------------------------------------------------AQRRPGDIQHLSPATENQPSPF-----T-----------RHGPS-------------------------------------------------------------------------------------------------------------VKGA-FKPDVVAHGGNVASNVRQGQWQA--HMRG--------------------------------L----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DVLSCHHQFQG-NTLFKELSG------TSFAAPYIT----H---------------------------L------------------AGRL----LN-----------------------------------------------------------------------------------EYP-------EMSA----------------------NMLRAML-------VNHASVSQEMTQAFPQAMRESYRNAPATRNREIERD---VTGYGIIDEDALYR------------------------------------------------------------------------------------1013
1014 ----------------------------------------------------------------------------------------P--II--------------V--------------------IID---------------------------S--------------GINRR---I--LGNNSFNKNSLNHKNKA--LKDEF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-C-----------------------AMVIK-------------------------------------------------------------------------------SI--CPDVEFISI-PILNKEGFSNSDNLEKALTYCLDIH----------------------------------------------------------C---------------------------------------------------------------------------------------------HI-----------------------------------------INLSLA-------------------------------------------------------------------------ILDNEDN--KIEELCTKLSKQNK-----V--------------------------------------------------------------------------------------I----------------ISSVRNNFIDSK------------------------------------------------------------------------------------------------------------------------------------------------------------------PAKYSS-----------------------------V---IG---V---R----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------------------------------------------------------------GGFSSIDKYWF--NSNYEIQ--------------------------------L------------------------------------------------------------------ITDMTPVFTDPQ-----LNRHFIFSG-----------------------------------------------------------------------------------------------------------------------------------NSKATAVAT----G---------------------------L------------------IAKIINEKKQ------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1014
1015 ----------------------------------------------------------------------------------------P--II--------------V--------------------IID---------------------------S--------------GINRR---I--LGNNSFNKNSLNHKNKA--LKDEF----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TA-C-----------------------AMVIK-------------------------------------------------------------------------------SI--CPDVEFISI-PILNKEGFSNSDNLEKALTYCLDIH----------------------------------------------------------C---------------------------------------------------------------------------------------------HI-----------------------------------------INLSLA-------------------------------------------------------------------------ILDNEDN--KIEELCTKLSKQNK-----V--------------------------------------------------------------------------------------I----------------ISSVRNNFIDSK------------------------------------------------------------------------------------------------------------------------------------------------------------------PAKYSS-----------------------------V---IG---V---R----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------G-------------------------------------------------------------------------------------------------------------------------------------------GGFSSIDKYWF--NSNYGIQ--------------------------------L------------------------------------------------------------------ITDMTPVFTDPQ-----LNRHFIFSG-----------------------------------------------------------------------------------------------------------------------------------NSKATAVAT----G---------------------------L------------------IAKIINEKKQVN----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1015
1016 ----------------------------------------------------------------------------------------V--KV--------------A--------------------VID---------------------------S--------------GVEYEHFDI--ISEKISGINLLNQKKELGDISDQL----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------GHG-------TAIC-----------------------SILSK-------------------------------------------------------------------------------S----DDITSIQVLKIFNNDYRVDLDKLIEAIEYAIYLN----------------------------------------------------------V---------------------------------------------------------------------------------------------DI-----------------------------------------INLSLG-------------------------------------------------------------------------ILQH-DNLMSLKIACQKAVEKGI-----V--------------------------------------------------------------------------------------I----------------VAACENSGEISY------------------------------------------------------------------------------------------------------------------------------------------------------------------PAEWDF-----------------------------V---IG---V--DT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------------------------------------------------------------KNVNKVDEFFFLENSSIEIQ---------------------------------------------------------------------------------------------------------AFGKPQKVAHLKSRHIVVND-----------------------------------------------------------------------------------------------------------------------------------NSYATPHIT----K---------------------------L------------------IAKIINKHGRKNIESIKKLLMKQAKQTIDLYQV-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1016
1017 ------------------------------------------------------------------------------------MNDQI--NV--------------A--------------------IID---------------------------D--------------GVNEKLYNTGVLKYNIEITPNLMIRERK-K-YDKYKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TT-C-----------------------AAIIK-------------------------------------------------------------------------------KY--LPYSVLSSI-KILNDKCEGSVEQLSLALKLCADKE----------------------------------------------------------I---------------------------------------------------------------------------------------------NL-----------------------------------------INLSLG-------------------------------------------------------------------------STYF-DDFEILKESLEYCYKKGV-----I--------------------------------------------------------------------------------------I----------------VAAISNENTYTY------------------------------------------------------------------------------------------------------------------------------------------------------------------PASLTN-----------------------------I---IG---VKCDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------------------------------------------------------------GRIKE-GKYIYIENSLDGVN--------------------------------I------------------------------------------------------------------IS---------------SGSHNIKNFKGINGITNNC-------------------------------------------------------------------------------------------------------------------------NSFVVPFII----S---------------------------E------------------VYNMMKENLHYDLNSVKKYLKQKSSNN------------LLEEID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1017
1018 ------------------------------------------------------------------------------------MNDQI--NV--------------A--------------------IID---------------------------D--------------GVNEKLYNTGVLKYNIEITPNLMIRERK-K-YDKYKS--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TT-C-----------------------AAIIK-------------------------------------------------------------------------------KY--LPYSVLSSI-KILNDKCEGSVEQLSLALKLCADKE----------------------------------------------------------I---------------------------------------------------------------------------------------------NL-----------------------------------------INLSLG-------------------------------------------------------------------------STYF-DDFEILKESLEYCYKKRV-----I--------------------------------------------------------------------------------------I----------------VAAISNENTYTY------------------------------------------------------------------------------------------------------------------------------------------------------------------PASLTN-----------------------------I---IG---VKCDK----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------K-------------------------------------------------------------------------------------------------------------------------------------------GRIKE-GKYIYIENSLDGVN--------------------------------I------------------------------------------------------------------IS---------------TGSHNIKNFKGINGITNNC-------------------------------------------------------------------------------------------------------------------------NSFVVPFII----S---------------------------E------------------VYNMMKENLHYDLNSVKKYLKQKSSNN------------LLEEID-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1018
1019 --------------------------------------------------------------------------------------------I--------------I--------------------IID---------------------------D--------------GVNSDLCNLGELKSDIEVTSDLEIKENL-DCYNEF-T--------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------ST-C-----------------------AAIIK-------------------------------------------------------------------------------KY--LPNAELGSI-KILSN-FKGTRYQLVKAIKWCVENN----------------------------------------------------------I---------------------------------------------------------------------------------------------KL-----------------------------------------INLSLG-------------------------------------------------------------------------TVNF-QDFKLLYSCMEYAYKKGL-----I--------------------------------------------------------------------------------------I----------------IAAYNNKRIYTC------------------------------------------------------------------------------------------------------------------------------------------------------------------PASFDN-----------------------------V---IG---VKCDT----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------T-------------------------------------------------------------------------------------------------------------------------------------------GTLKR-SEYIYNTYSLDGIE--------------------------------V------------------------------------------------------------------IA---------------NAKHNIIDNSGMVYTTSIC-------------------------------------------------------------------------------------------------------------------------NSYATPVVT----A---------------------------L------------------VYELIEKYPDITINEIKTYLRNRSVNNNNSIDLIKRNHKIQKNVDVPVMIFYDFTGYYGATISKLFCELFRANGYYAIAIVDSILKSSKHE---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------1019
1020 --------------TLKLINAENFLPYKGNTSKI-------------------------------------------------------------------------A--------------------IID---------------------------T--------------GINE-S------N-------------V---------F--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QNTNMEQFNID----------EKSKVSQ-----------------------------------------------------------------------------------------Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TM-V-----------------------AGIII----SNG--------------------------------------------------------------NGYTEP---GGL--IPN-S--KVISI---QS---GTDM------------GM--T------------SKD-------------------------------------L--------AKS--------------I-----------DL---SV--------------------E-----K------G----------A----KI-----------------------------------------INISSG----------TTKK----------------------ND--------------------------VLEK-----SVND---------ALSK----GV-----V--------------------------------------------------------------------------------------I---------------IAANG-ND--------SK---------N--------TLFY---------------------------------------------------------------------------------------------------------------------------------------P-ASYK-G---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------NE-------R----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KP-MNV-----S--D--------I-G------------------------KV------------------------------------------------D-----I------F-----------------A-----P-------------G-------------------------------------------------EEL------------------------------------------------------------------LT-TRA-----------------------------------------------------------------------------------------------DQKDYKGS---------------------------------------FGG------NSAATPVVT----S---------------------------I------------------VA-Y----LL----S-------SYPQIK-----------------------------------------------------------------PGN--------------I---------------------ESIL-------VNNS---DVIK------------------------------------------------------------------------------------------------------------------------------1020
1021 ---------------LKIINAEDYLPYKGKTPKI-------------------------------------------------------------------------A--------------------IID---------------------------T--------------GVDL-N------N-------------N---------F--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KDTNLDQFYLD----------EKSKVSQ-----------------------------------------------------------------------------------------Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------YHG-------TM-V-----------------------AGILI----SNG--------------------------------------------------------------DGYTNP---GGL--IPK-S--QVLSI---QS---GTDM------------GM--T------------SND-------------------------------------L--------AKA--------------I-----------DL---SV--------------------K-----K------G----------A----KV-----------------------------------------INISSG----------TTKQ----------------------NE--------------------------VLEK-----SVNE---------ALSK----GV-----V--------------------------------------------------------------------------------------I---------------IASNG-ND--------SK---------N--------KLYY---------------------------------------------------------------------------------------------------------------------------------------P-ASYK-G---------------------------V---IS---VG--A------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------KD-------R----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------KP-INI-----S--D--------I-G------------------------KV------------------------------------------------D-----I------F-----------------A-----P-------------G-------------------------------------------------EEL------------------------------------------------------------------LT-TRT-----------------------------------------------------------------------------------------------DQKNHKGL---------------------------------------FGG------NSAATPVVT----S---------------------------I------------------VA-Y----LL----S-------NYPEIT-----------------------------------------------------------------AEN--------------V---------------------EDIL-------INNS---DVGKQKDQDIK-----------------------------------------------------------------------------------------------------------------------1021
1022 ---------------------------KQITSKI-------------------------------------------------------------------------A--------------------VID---------------------------T--------------GVKL-D------N-------------T---------F--------------------------------L---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EKSIIKQEYTD----------QMSQSSQ-----------------------------------------------------------------------------------------Q----------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------TM-V-----------------------TGILT----SNG--------------------------------------------------------------NGHSGP---GGL--IPK-S--NILSI---QT---GTDL------------GM--S------------SKQ-------------------------------------L--------IQA--------------I-----------NI---AI--------------------D-----N------N----------V----KI-----------------------------------------INISLG----------TTKD----------------------SP--------------------------ELQT-----VIKK---------ALEK----DI-----T--------------------------------------------------------------------------------------I---------------VASAG-NN--------GN---------S--------INYY---------------------------------------------------------------------------------------------------------------------------------------P-AAYE-G---------------------------V---IS---VG--S------------------------------I------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N-------------------------------------------------------------------------------------EK-------K----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EI-SNS-----L--N--------L-S------------------------NI------------------------------------------------N-----I------F-----------------A-----P-------------G-------------------------------------------------ENL------------------------------------------------------------------LT-TTA-----------------------------------------------------------------------------------------------NKKE-QDY---------------------------------------FTG------NSAATPVIT----S---------------------------I------------------VA-V----MI----T-------ENPNLT-----------------------------------------------------------------NSD--------------I---------------------KSIL-------VSSA---DTKT------------------------------------------------------------------------------------------------------------------------------1022
1023 -----LHPHDLDERIPGLADLHNQTLGDPQITIVIIDGDPDYT---------LSC-FEGA--------------------------EVS--KV--------------FPYWHEPAEPITPEDYAAFQSIRD---------------------------Q--------------GLKG-K------E-------------K---------E----------------------------------------------------EALEAVIPDTKD-----RIVLN------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DHA-------CH-V-----------------------TSTIV----GQE----------------------------------------------------------------HSPV---FGI--APN-C--RVINM---PQ----DAV----------I-RG--N------------YDD-------------------------------------V--------MSP--------------L-----------N---------------------------------------L----------ARA--ID-----------------------------------------LALELGANIIHCAF-CRPTQTS-------------EGEEILVQ------------------------------------AIKK---------CQDN----NV-----L--------------------------------------------------------------------------------------I---------------VSPTG-NN-------------------SNE----SWCL-----------------------------------------------------------------------------------------------------------------------------------------P-AVLPGT-------------------------------LA---VG--A-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AKVDGTPCHF-----S--N--------W-GGN-N----------------------------------------------------------------------TKEG--I------L-----------------A-----P-------------G-----------------EE--------------------------------I------------------------------------------------------------------LG------------------------------------------------------------------------------------------------------------------AQPCTEE---PVR-------------------LTG------TSMAAPVMT----G---------------------------I------------------SALL----MSLQVQQ-----------------------------------------------------------------------------------------------G------------------KPVDAEA-------VRTALLKTAIPCDPEVVEEPERCLRGFVNIPGAMKVLFGQPSVTVSFAGGQATRTEHPGYATVAPASIPEPMAERATPAVQAATATEMVIAPSTEPANPATVEASTAFSGNVYALGTIGYDF---------------1023
1024 ----------------------------------------------------------------------------------------I--RV--------------A--------------------ILD---------------------------G--------------PVDI-A------H-------------P---------C--------------------------------F---------------------Q----------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------A-----DLTV--------------LP------------TL-----------------------------------------------------------------------------------------A---P---------------------TAARSDGFM----------------------------------------------------------------------SA-------------------------------------------------------------------HG-------TH-V-----------------------ASIIF----G-------------------------------------------------------QPETSVP------------GI--APQ-C--RGLIV---PI---FSDD----------RRRI--T------------QLD-------------------------------------L--------ARG--------------I-----------ER---AV-----NAG------------------------------------A----HI-----------------------------------------INISGGELTD--FG-EAD-------------------------G--------------------------WLEN-----AVSL-C--------RQN----NV-----L--------------------------------------------------------------------------------------L---------------VAAAG-NN--------GC---------D--------CLHV---------------------------------------------------------------------------------------------------------------------------------------P-A----A----LPA--------------------V---LA---VG--A------------------------------M-----------------------------D------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------D-------------------------------------------------------------------------------------HG-------H-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------P-LDF-----S--N--------W-G---S--------------------TY------------------------------------------------EQQG--I------L-----------------A-----P-------------G------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EDIL-----GAKPGG--------GT-ER----------------LSG------TSFATPIVS----G---------------------------V------------------AA-L----LL----S-------EQVRRG-----------------------------------------------------------------ETP--------------D---------------------PQKV-------RQL-------------------------LL------------------------------------------------------------------------QSAL-PCDDDAPEQARRCLAGRLNVSGAFTLLKGG1024
1025 ----------------------------NAQVSSNVTIPKDTREEDGKVAGVNVGLLEGE--------------------------G-V--KV--------------A--------------------ILD---------------------------S----------------------------------------------------------DFQNAVRSSAKNEDGTAAIVRRTRALNVIFPGTEVDIIPRITSEVRAKDGTLIATTPTTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------QHG-------EE-V--LEVLRDMDSSGGPYYNRIHTILGSFGLDFYDPDES--------------------------------------------------------------------------KNLFGAVLANKETYDAALTRFG-N------------QS-------------------------------------------------------V---------------------------------------------------------------------------------------------KI-----------------------------------------FNQSFGGN-----KA--YDDSS-------------LAQYRNE----------GDSLPLYFNKVVGSTAPQVKQVPYFRDIVENKG---------------GL-----F--------------------------------------------------------------------------------------V----------------WAAG-ND-----------------------------------------------------------------------------------------------------------------------------------------------------------------------AG-------------KNSSLNAGLPYFEHRLEPGWI---ST---VGVLDEDNGKYYVLGRGN---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------YELS--------KAGFE-------------------------------------------------------------------------------AKWWSIS-----------------A-----LMYSAKNSQETDPNK----------------------------------------------------------------------------------------------------------------------KV--------------------------------------------------------------------------------------------------------------------------------------------------GIG------SSYAAPRVT----M---------------------------A------------------AALV----YE------------KYPWMT----------------------------------------------------------------------------------N------------------DQIRQTL-------FTT------------------------------------------------------------------------------------TDKTELT-EDPDTLSEAKLRNVTAFPDYTYGWGMLNTERALK--------1025
1026 ----------------KGNISALKEKLNRNRENSTATIPTETI------------SYNGS--------------------------T-V--KI--------------G--------------------ILD---------------------------S----------------------------------------------------------DFTDPVRKA---------------QLSARYPG--IEFIPRVNSD------------TSTS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------SHG-------VQ-V--LEVMMDTLEDRTKGKAKFKAIAASIG---NGG--A--------------------------------------------------------------------------SETNKSVNPNVKTYEKVFERFNFN------------QK-------------------------------------------------------V---------------------------------------------------------------------------------------------KV-----------------------------------------VNQSFGADITIEEAP--YTKNN-------------IRNYVWA----------GDSKPF---------------ATYFEEKVNNDG---------------GL-----F--------------------------------------------------------------------------------------V----------------WAAG-NR-----------------------------------------------------------------------------------------------------------------------------------------------------------------------KGATETNPGQDM---DSVGMEAGLPYLVNDLEKGWI---AV---VGIQPKETVRVGTAPDGTPIVNIKPNGKLNIHRTGT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------DRLA--------YAGDN-------------------------------------------------------------------------------AKYWSIS-----------------A-----------DDSAIPTAG----------------------------------------------------------------------------------------------------------------------RA--------------------------------------------------------------------------------------------------------------------------------------------------GIG------SSYAAPRVS----R---------------------------A------------------AALV----AE------------KFDWMT----------------------------------------------------------------------------------A------------------DQVRQTL-------FTT------------------------------------------------------------------------------------TDDTELDASLAGNANAEKRRRVKTSPDYKYGWGMLNQERALK--------1026
1027 -----------------MDETKVREFIFNEQNNSIENIPMDNR------------VLNGD--------------------------K-V--KV--------------G--------------------VLD---------------------------G----------------------------------------------------------DFIN--KKN---------------YLENKYGN--IEILER-NYN------------PKHS-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------NHG-------EL-V--LKVL--------REKNKLGIIAGSIG---ENDDFS--------------------------------------------------------------------------GKEGTTVIPKLETYEKVLEKFNPN------------QK-------------------------------------------------------V---------------------------------------------------------------------------------------------KV-----------------------------------------FSQSWGVPETI--GS--YISKS-------------EEERMRAI---APGQTSSEGRKI---------------LDFYKKEVNKD----------------TL-----F--------------------------------------------------------------------------------------I----------------WANG-N---------------------------------------------------------------------------------------------------------------------------------------------------------------------------TLVNNQNQVVLFNDAYYQGGLPHLYSELEKGWI---TV---VGVKKK---------DGN---------MLNKHYTDT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------AHLA--------YPG-N-------------------------------------------------------------------------------AKWWAIS-----------------A-----------DAEVVDSKG----------------------------------------------------------------------------------------------------------------------VT--------------------------------------------------------------------------------------------------------------------------------------------------HRG------SSFAAPRVA----K---------------------------V------------------AALV----AE------------KYDWMT----------------------------------------------------------------------------------A------------------DQVRQTL-------FTT------------------------------------------------------------------------------------TDRTNID------ENETYIRNIVTEPDEKYGWGMLNRERALK--------1027
1028 ----------------------------PNLHTGDFPNPNDAYKNLINLKPAIEAGYTGR--------------------------G-V--EV--------------G--------------------IVD---------------------------T--------------GESVGS------I-------------SFPELYGRKEHGYNENYKNYTAYMRKEAPEDGGGK-------DIEASFDD---EAVIETEAK------------PTDI-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------RHV-------KE-IGHIDLVSHIIGGRSVDGRPAGGIAPDATLHIMNTNDG--------------------------------------------------------------------------TKNEMMVAAIRNAWVKLGER-----------------G-------------------------------------------------------V---------------------------------------------------------------------------------------------RI-----------------------------------------VNNSFGTTSRAGTADLFQIANS-------------EEQYRQALLDYSGGDKTDEGIRLMQQSDYGN-------LSYH---IRNKN---------------ML-----F--------------------------------------------------------------------------------------I----------------FSTG-ND-----------------------------------------------------------------------------------------------------------------------------------------------------------------------AQ-------------AQPNTYALLPFYEKDAQKGII---TV---AGV-DRSGEKFKREMYGE---------------PGT---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------EPLE--------YGSNHCG----------------------------------------------------------------------------ITAMWCLS-----------------A-----PYEASVRFTRTNPIQ----------------------------------------------------------------------------------------------------------------------IA----------------------------------------------------------------------------------------------------------------------------------------------------G------TSFSAPIVT----G---------------------------T------------------AALL----LQ------------KYPWMS----------------------------------------------------------------------------------N------------------DNLRTTL-------LTT------------------------------------------------------------------------------------AQDIG-----------------AVGVDSKFGWGLLDAGKALN--------1028
1029 -------------------QAEDTRQLLNANSDLLNTTGNVTGL--------TGA-FNGE--------------------------N-I--KF--------------T--------------------VFD---------------------------G--------------GRIY-E------T-------------H---------D--------------------------------A-----------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------FNNA-----TGRITN--------------------------KEASTQSY---------SD-------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------HS-------TG-V-----------------------GSFIG----GKSVN--------------------------------------------------------------LSSGEVPVGN--AKG-V----------AI-----------------N--------STM-DSYMFNTTT-------------------------------------L--------PNN--------------------------TA--TST--------------------------------------------VFQKILIAQPNISNHSYGVNSGWTGTYANNNYASFTYNGYKAGDTFYDYQGTYNTND-VNYD-NI--------------------------------------------------------------AYNNPS-YIIVK-SAGN----YF-----N--------------------------------------------------------------------------MGPTGTGSSAPKY----------------YNSG-N-------------------------------------------------------------------------------------------------------------------------------------------------------------------------GAVAFAATDTLPPDNCSL-GYDCIGTGSLAKNIIV---VGATDII--T------------------------------T---------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------------N--N--------N-RYT-------------------------------------------------------------------------TASDVV------------------------HSSYS-S-------------AGPRDDGGIKPDISTVGTNV---------------------------LYAATV------------------------------------------------------------------TT--------------------------------------------------------------------------------------------------------------------------------T-----------GSTWAQNSG------TSFSAPIVT----G---------------------------I------------------IGLW----TQ------------INKQLFNNALLNASSAKTLTIHSASEAGNIGPDPHFGWGFINAKKGADLLVGKSNGSVIFTDETLTSGVTNSKTIKASGSEPLKVTISW------------------LDPKYIPNYQFVSDVFNNRTSKLINDID-------------LRIIDTTTNTIYYPWKLDADSPMTPATKADNTVDNVEQVVLDNPVPGRNYRIEVTNKGTLVNDAG---------------------------------------------1029