18 December 2018

New sheep DQ allelic sections

The sheep section now includes 82 full-length and partial cDNA alleles at the DQA1, DQA2, DQA2-like, DQB1, DQB2 and DQB2-like genes.

For some time sheep DQ alleles from have not been represented on the IPD-MHC Database due to gene duplications and lack of full length sequences representing each of the DQA and DQB loci. Rather than assigning all DQA and DQB alleles in single allelic series we have assigned each sequence to an individual locus as detailed in Ballingall et al (2018). The sheep section now includes alleles at the DQA1, DQA2, DQA2-like, DQB1, DQB2 and DQB2-like genes.

  • Keith T. Ballingall, Kara Dicks, Panoraia Kyriazopoulou, Lynne Herrmann-Hoesing. Allelic nomenclature for the duplicated MHC class II DQ genes in sheep. Immunogenetics (2018), DOI: 10.1007/s00251-018-1096-9.
Edited by Dr. Keith Ballingall