Multiple Sequence Alignment
The multiple alignment tool allows to display single locus alignments, as well as inter- and intra- species loci alignments from all groups within the IPD-MHC Database. This is achieved by a hybrid approach that combines precomputed alignments of single loci with dynamic inter- and intra- species sequence alignments. Where discrepancies have arisen between reported sequences and those stored in the database, the original authors have been contacted where possible, and necessary amendments to published sequences have been incorporated into this alignment. Future sequencing may identify errors in this list and the Nomenclature Committee would welcome any evidence that helps to maintain the accuracy of these sequence alignments.
Please note that, because the tool allows the customised visualization of exons and introns sequences, at the current time numbering is based on the gDNA sequence.
Further help can be found in the help which details both the input options and how the alignments are displayed. Alignments can be downloaded from the download page.