The numbers below represent the number of named alleles for each gene. This number includes alleles which have been named but whose sequences are still held as confidential. This means that the number of sequences found in some files may differ to the numbers printed in this table. Details of which alleles are still confidential can be seen in the latest version report. The numbers below do not include the names of any deleted alleles - details of deleted alleles can be found in a separate report.

Numbers of HLA Alleles
HLA Class I Alleles 14,800
HLA Class II Alleles 5,288
HLA Alleles 20,088
Other non-HLA Alleles 184
Number of Confidential Alleles 3
HLA Class I
Gene A B C E F G
Alleles 4,638 5,590 4,374 27 31 61
Proteins 3,172 3,923 2,920 8 6 19
Nulls 224 169 171 1 0 3
HLA Class I - Pseudogenes
Gene H J K L N P S T U V W Y
Alleles 12 9 6 5 5 5 7 8 5 3 11 3
Proteins 0 0 0 0 0 0 0 0 0 0 0 0
Nulls 0 0 0 0 0 0 0 0 0 0 0 0
HLA Class II
Gene DRA DRB DQA1 DQB1 DPA1 DPA2 DPB1 DPB2 DMA DMB DOA DOB
Alleles 7 2,639 100 1,316 73 5 1,097 6 7 13 12 13
Proteins 2 1,908 36 878 32 2 728 3 4 7 3 5
Nulls 0 84 4 35 0 0 34 0 0 0 1 0
HLA Class II - DRB Alleles
Gene DRB1 DRB2 DRB3 DRB4 DRB5 DRB6 DRB7 DRB8 DRB9
Alleles 2,300 1 175 83 68 3 2 1 6
Proteins 1,644 0 142 63 59 0 0 0 0
Nulls 62 0 7 11 4 0 0 0 0
Other non-HLA Genes
Gene HFE MICA MICB TAP1 TAP2
Alleles 6 107 47 12 12
Proteins 4 82 30 6 5
Nulls 0 2 2 1 0

Database Growth
Release Month Alleles Component Entries
1.0
1998-12
964
1,853
1.1
1999-04
980
2,038
1.3
1999-08
1,007
2,257
1.4
1999-10
1,015
2,275
1.5
2000-01
1,116
2,444
1.6
2000-04
1,156
2,566
1.7
2000-07
1,220
2,620
1.8
2000-10
1,257
2,976
1.9
2001-01
1,341
3,028
1.10
2001-04
1,390
3,349
1.11
2001-07
1,437
3,349
1.12
2001-10
1,467
3,558
1.13
2002-01
1,496
3,572
1.14
2002-04
1,519
3,634
1.15
2002-07
1,546
3,734
1.16
2002-09
1,588
3,868
2.0
2003-01
1,620
3,956
2.1
2003-04
1,646
4,029
2.2
2003-07
1,695
4,139
2.3
2003-10
1,738
4,238
2.4
2004-01
1,777
4,331
2.5
2004-04
1,814
4,405
2.6
2004-07
1,883
4,519
2.7
2004-10
1,935
4,666
2.8
2005-01
1,972
4,768
2.9
2005-04
2,076
4,949
2.10
2005-07
2,182
5,224
2.11
2005-10
2,280
5,510
2.12
2006-01
2,337
5,585
2.13
2006-04
2,429
5,598
2.14
2006-07
2,533
5,753
2.15
2006-10
2,607
5,849
2.16
2007-01
2,683
5,957
2.17
2007-04
2,816
6,139
2.18
2007-07
2,901
6,246
2.19
2007-10
3,043
6,430
2.20
2008-01
3,095
6,506
2.21
2008-04
3,187
6,693
2.22
2008-07
3,201
6,840
2.23
2008-10
3,410
7,028
2.24
2009-01
3,477
7,122
2.25
2009-04
3,635
7,585
2.26
2009-07
3,864
7,940
2.27
2009-10
4,161
9,115
2.28
2010-01
4,556
9,819
3.0
2010-04
4,743
10,245
3.1
2010-07
5,302
11,144
3.2
2010-10
5,788
11,914
3.3
2011-01
6,189
12,618
3.4
2011-04
6,534
13,381
3.5
2011-07
6,944
14,497
3.6
2011-10
7,196
15,187
3.7
2012-01
7,269
16,745
3.8
2012-04
7,670
17,261
3.9
2012-07
8,159
17,832
3.10
2012-10
8,644
18,407
3.11
2013-01
8,949
19,086
3.12
2013-04
9,310
19,659
3.13
2013-07
9,564
20,240
3.14
2013-10
10,104
20,781
3.15
2014-01
10,691
22,291
3.16
2014-04
11,389
23,222
3.17
2014-07
12,010
24,246
3.18
2014-10
12,407
24,910
3.19
2015-01
12,707
25,361
3.20
2015-04
13,190
26,003
3.21
2015-07
13,580
26,583
3.22
2015-10
14,015
27,286
3.23
2016-01
14,409
27,805
3.24
2016-04
14,473
28,838
3.25
2016-07
15,020
29,205
3.26
2016-10
15,819
30,152
3.27
2017-01
16,429
31,208
3.28
2017-04
16,933
32,106
3.29
2017-07
17,344
32,640
3.30
2017-10
17,509
32,919
3.31
2018-01
17,874
33,978
3.32
2018-04
18,363
35,057
3.33
2018-07
18,955
36,161
3.34
2018-10
20,272
38,209

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