{"metadata":{"accession":"G3TQL3","id":"G3TQL3_LOXAF","source_organism":{"taxId":"9785","scientificName":"Loxodonta africana","fullName":"Loxodonta africana (African elephant)"},"name":"Lysosome-associated membrane glycoprotein 3","description":["Lysosomal membrane glycoprotein which plays a role in the unfolded protein response (UPR) that contributes to protein degradation and cell survival during proteasomal dysfunction. Plays a role in the process of fusion of the lysosome with the autophagosome, thereby modulating the autophagic process. Promotes hepatocellular lipogenesis through activation of the PI3K/Akt pathway. May also play a role in dendritic cell function and in adaptive immunity"],"length":427,"sequence":"MSWQFPAVAVLFVSLAVIFRYGSQIEEAFPEASDHLQPTTAATIQARPSFPQPTSQMPHKALTARSTDGHATYQIAATTSKSENPTTHAMIKTPATTTSVTTESIPSTSPVTHALITTQATPNISQSAHQVTEATIGSSAAPGSQSAALNPPAHTTMTHPSTVSPTAEETTQPSNQTSLPATLPTTPCNSTTSQMPTQPIHTPGTTTATHNATQTAPPVPPAPGPTLAPQPLPTKIGIYQVLNGSRLCIKAELGIELIVQDEESVFSPQRYFNINPNVTQASGNCGPRKSNLLLNFQGGFVNFTFTKDENSYCISEVGAFLTDSHPERIYQGMKSAMVLFETTAGHSFKCVSEQSIRLSTHLQLKTTNVQLQAFDFEGDNFGNVDECSSDYTIVLPVIGATVLGLCAVGLIVYGVRLRRESSGYQRI","proteome":"UP000007646","gene":"LAMP3","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"fe10e2c788edaa199f0fb00a2d8fa42418066370","counters":{"domain_architectures":3037,"entries":7,"isoforms":0,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"profile":1,"pfam":1,"cathgene3d":1,"panther":1,"prints":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":3037}}}