{"metadata":{"accession":"W7N1I1","id":"W7N1I1_GIBM7","source_organism":{"taxId":"334819","scientificName":"Gibberella moniliformis (strain M3125 / FGSC 7600)","fullName":"Gibberella moniliformis (strain M3125 / FGSC 7600) (Maize ear and stalk rot fungus)"},"name":"4-amino-5-hydroxymethyl-2-methylpyrimidine phosphate synthase","description":["Responsible for the formation of the pyrimidine heterocycle in the thiamine biosynthesis pathway. Catalyzes the formation of hydroxymethylpyrimidine phosphate (HMP-P) from histidine and pyridoxal phosphate (PLP). The protein uses PLP and the active site histidine to form HMP-P, generating an inactive enzyme. The enzyme can only undergo a single turnover, which suggests it is a suicide enzyme"],"length":342,"sequence":"MSTDKITFLTNWHATPYHAPLYLAQAKGYFKDEGIKVALLEPNDPSDVTEIIGTGKVDLGFKAMIHTLAAKARNFPVQSIGSLLDEPFTGVVYLKDSGITTDFRTLKGKRIGYVGEFGKIQIDELTSHYGMTPDDYTAVRCGMNVSKAIIKGEIDAGIGLENVQMVELEEWLSAQGRPKDDVQMLRIDELAELGCCCFCTILYIGNEKFLAENPEKVRSFLRAVKKATDFVLAEPEKAWAEYVDFKPVMGTALNRKIFERSFAYFSKDLKNVKRDWEKVTKYGKRLGVLDESFEPNYTNSYLEWTLSGESSDPTGDQKRIAQLQKDVAASGGFHRLQAEVKA","proteome":"UP000009096","gene":"FVEG_09760","go_terms":[{"identifier":"GO:0009228","name":"thiamine biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"ida_accession":"a7843b174854e51b1f7bf70c154a1e948dc81e7c","counters":{"domain_architectures":48872,"entries":7,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"cdd":1,"cathgene3d":1,"panther":1,"pfam":1,"interpro":2},"proteome":1,"taxonomy":1,"similar_proteins":48872}}}