{"metadata":{"accession":"S7Z8X5","id":"S7Z8X5_PENO1","source_organism":{"taxId":"933388","scientificName":"Penicillium oxalicum (strain 114-2 / CGMCC 5302)","fullName":"Penicillium oxalicum (strain 114-2 / CGMCC 5302)"},"name":"Lipoyl synthase, mitochondrial","description":["Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives"],"length":418,"sequence":"MSASTRAFQRLSSVRSTGQFLGSSVFPITSRSYATTDASSATSTSSDAMTRRRATTFKDKLNAGPSFSDFVSGGKEEPLDASEAYELKTALVGPAGRKKEMTRLPSWLKTPIPDSKNYQRLKKDLRGLNLHTVCEEARCPNISDCWGGSDKSAATATIMLMGDTCTRGCRFCSVKTSRTPAPLDPHEPENTAEAISRWGLGYVVLTSVDRDDLADGGARHFAETVIKIKQKAPNILVECLTGDYWGNMDMVALVARSGLDVYAHNVETVEALTPHIRDRRATFQQSIRVLDAAKQARPDLITKTSLMLGFGETDEQIEDALRQLRAVKVDVVTFGQYMRPSKRHMAVHEYVTPDRFEFWRKRALEMGFLYCASGPLVRSSYKAGEAFIENVLKKRRAASGGVTSAMDSASASTDKPVA","proteome":"UP000019376","gene":"PDE_02001","go_terms":[{"identifier":"GO:0003824","name":"catalytic activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051536","name":"iron-sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0016992","name":"lipoate synthase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0051539","name":"4 iron, 4 sulfur cluster binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0009107","name":"lipoate biosynthetic process","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"652f37e3fd8b5e19aed3c03ec114c4d88eb8056e","counters":{"domain_architectures":19401,"entries":21,"isoforms":0,"proteomes":1,"sets":2,"structures":0,"taxa":1,"dbEntries":{"ssf":1,"profile":1,"cathgene3d":1,"smart":1,"pfam":2,"cdd":1,"panther":1,"sfld":3,"ncbifam":3,"hamap":1,"interpro":6},"proteome":1,"taxonomy":1,"similar_proteins":19401}}}