{"metadata":{"accession":"Q9Y1B2","id":"ORC6_DROME","source_organism":{"taxId":"7227","scientificName":"Drosophila melanogaster","fullName":"Drosophila melanogaster (Fruit fly)"},"name":"Origin recognition complex subunit 6","description":["Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication (By similarity)"],"length":257,"sequence":"MTTLIEQLITKMGLREEPNVLEKTTELVRLLELRSTNVPLQINEYGKIVLCADLASCMIGIAFDKEQALKLSGLRKSQYLNNKRMFEKLLDLNKLASVNDICVQLGLNEVARKAEELMTLFKGVAATEDMGTDTSHPQYATMAVFQACRLLKKKVSKSKLMPFSNLRPSQFQLLEQQWERMIAKHHKESKVPSSTDMEGKLKENQNENIKGHEAKKAHKPPPEDYEIWKARMLAKAQAKLKELEASQSHMDSQLLEA","proteome":"UP000000803","gene":"Orc6","go_terms":[{"identifier":"GO:0003677","name":"DNA binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006260","name":"DNA replication","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0005664","name":"nuclear origin of replication recognition complex","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"a614704ef6632d5e1aec73f13bcce9c15d661d07","counters":{"domain_architectures":1705,"entries":9,"isoforms":0,"proteomes":1,"sets":2,"structures":8,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":2,"cdd":2,"panther":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":1705}}}