{"metadata":{"accession":"Q9UIJ7","id":"KAD3_HUMAN","source_organism":{"taxId":"9606","scientificName":"Homo sapiens","fullName":"Homo sapiens (Human)"},"name":"GTP:AMP phosphotransferase AK3, mitochondrial","description":["Mitochondrial adenylate kinase with a specific GTP:AMP phosphotransferase activity (PubMed:11485571, PubMed:32822537). Could also use ITP as phosphate donor (PubMed:11485571). Its physiological function is to recycle GTP into GDP which is necessary for the TCA cycle in the mitochondrial matrix (Probable)"],"length":227,"sequence":"MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFIDQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEVIKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQTKPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP","proteome":"UP000005640","gene":"AK3","go_terms":[{"identifier":"GO:0005524","name":"ATP binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0019205","name":"nucleobase-containing compound kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0006139","name":"nucleobase-containing compound metabolic process","category":{"code":"P","name":"biological_process"}},{"identifier":"GO:0004017","name":"AMP kinase activity","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0005739","name":"mitochondrion","category":{"code":"C","name":"cellular_component"}},{"identifier":"GO:0016776","name":"phosphotransferase activity, phosphate group as acceptor","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"cd3ce6da6122bbe1e4b04d5ae2a462ecdf76a3f9","counters":{"domain_architectures":27793,"entries":19,"isoforms":3,"proteomes":1,"sets":3,"structures":4,"taxa":1,"dbEntries":{"cathgene3d":1,"cdd":1,"ssf":2,"pfam":2,"hamap":2,"panther":1,"ncbifam":1,"prosite":1,"prints":1,"interpro":7},"proteome":1,"taxonomy":1,"similar_proteins":27793}}}