{"metadata":{"accession":"Q8NBV8","id":"SYT8_HUMAN","source_organism":{"taxId":"9606","scientificName":"Homo sapiens","fullName":"Homo sapiens (Human)"},"name":"Synaptotagmin-8","description":["Involved in the trafficking and exocytosis of secretory vesicles in non-neuronal tissues. Mediates Ca(2+)-regulation of exocytosis acrosomal reaction in sperm. May mediate Ca(2+)-regulation of exocytosis in insulin secreted cells"],"length":387,"sequence":"MGHPPVSPSAPAPAGTTAIPGLIPDLVAGTPWPRWALIAGALAAGVLLVSCLLCAACCCCRRHRKKPRDKESVGLGSARGTTTTHLVQPDVDGLESSPGDAQQWGCLQLSLEFDFGSQEIRVGLRQAADLRPGGTVDPYARVSVSTQAGHRHETKVHRGTLCPVFDETCCFHIPQAELPGATLQVQLFNFKRFSGHEPLGELRLPLGTVDLQHVLEHWYLLGPPAATQPEQVGELCFSLRYVPSSGRLTVVVLEARGLRPGLAEPYVKVQLMLNQRKWKKRKTATKKGTAAPYFNEAFTFLVPFSQVQNVDLVLAVWDRSLPLRTEPVGKVHLGARASGQPLQHWADMLAHARRPIAQRHPLRPAREVDRMLALQPRLRLRLPLPHS","proteome":"UP000005640","gene":"SYT8","go_terms":[{"identifier":"GO:0016020","name":"membrane","category":{"code":"C","name":"cellular_component"}}],"protein_evidence":1,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"76351f8e62ff50d525de723680d4da52aca317c5","counters":{"domain_architectures":34302,"entries":10,"isoforms":2,"proteomes":1,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"ssf":1,"profile":1,"smart":1,"pfam":1,"panther":1,"prints":1,"interpro":3},"proteome":1,"taxonomy":1,"similar_proteins":34302}}}