{"metadata":{"accession":"Q6QPD2","id":"Q6QPD2_9ADEN","source_organism":{"taxId":"35266","scientificName":"Simian adenovirus 23","fullName":"Simian adenovirus 23"},"name":"Early E3 18.5 kDa glycoprotein","description":["Binds and retains class I heavy chains in the endoplasmic reticulum during the early period of virus infection, thereby impairing their transport to the cell surface. Also delays the expression of class I alleles that it cannot affect by direct retention. Binds transporters associated with antigen processing (TAP) and acts as a tapasin inhibitor, preventing class I/TAP association. In consequence, infected cells are masked for immune recognition by cytotoxic T-lymphocytes"],"length":176,"sequence":"MGKITLVSCGALVAVLLSIVGLGGAAVVKEKADPCLHFNPNKCQLSFQPDGNRCAVLIKCGWECENVRIEYNNKTRNNTLASVWQPGDPEWYTVSVPGADGSPRTVNNTFIFAHMCNTVMWMSKQYDMWPPTKENIVVFSIAYSLCTALITAIVCLSIHMLIAIRPRNNAEKEKQP","proteome":null,"gene":null,"go_terms":[{"identifier":"GO:0005537","name":"D-mannose binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0052031","name":"symbiont-mediated perturbation of host defense response","category":{"code":"P","name":"biological_process"}}],"protein_evidence":3,"source_database":"unreviewed","is_fragment":false,"in_alphafold":false,"in_bfvd":false,"ida_accession":"c09a65c6fe180942917741a571d8d65402d8e8f0","counters":{"domain_architectures":212,"entries":4,"isoforms":0,"proteomes":0,"sets":1,"structures":0,"taxa":1,"dbEntries":{"cathgene3d":1,"pfam":1,"interpro":2},"proteome":0,"taxonomy":1,"similar_proteins":212}}}