{"metadata":{"accession":"Q6P616","id":"RBM22_XENTR","source_organism":{"taxId":"8364","scientificName":"Xenopus tropicalis","fullName":"Xenopus tropicalis (Western clawed frog)"},"name":"Pre-mRNA-splicing factor RBM22","description":["Required for pre-mRNA splicing as component of the activated spliceosome. Involved in the first step of pre-mRNA splicing. Binds directly to the internal stem-loop (ISL) domain of the U6 snRNA and to the pre-mRNA intron near the 5' splice site during the activation and catalytic phases of the spliceosome cycle"],"length":417,"sequence":"MATSLGSNTYNRQNWEDADFPILCQTCLGENPYIRMTKEKYGKECKICARPFTVFRWCPGVRMRFKKTEVCQTCSKLKNVCQTCLLDLEYGLPIQVRDAGASLKDEMPRSDVNKEYYTQNMEREIANSDGTRPVGALGKATSSSDMLLKLARTTPYYKRNRPHICSFWVKGECKRGEECPYRHEKPTDPDDPLADQNIKDRYYGINDPVADKLLKRASTMPRLDPPEDKSITTLYVGGLGDTISESELRNHFYQFGEIRTITVVQRQQCAFIQFATRQAAEMAAEKSFNKLIVNGRRLNVKWGRSQAARGKERERDGSSDPGMKLEPVPGLPGALPPPPTEEESSANYFNLPPNGSAALVNISLPPPPGLSGPPPGYGPHMFPPMAPPPFLRAPGHIHYPSQDPQRMGAHAGKPSSG","proteome":"UP000008143","gene":"rbm22","go_terms":[{"identifier":"GO:0046872","name":"metal ion binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003676","name":"nucleic acid binding","category":{"code":"F","name":"molecular_function"}},{"identifier":"GO:0003723","name":"RNA binding","category":{"code":"F","name":"molecular_function"}}],"protein_evidence":2,"source_database":"reviewed","is_fragment":false,"in_alphafold":true,"in_bfvd":false,"ida_accession":"330e40ab60ecffb9fdc2b44d9a716e300070693d","counters":{"domain_architectures":1626,"entries":21,"isoforms":0,"proteomes":1,"sets":4,"structures":0,"taxa":1,"dbEntries":{"pfam":3,"cathgene3d":2,"smart":2,"profile":2,"ssf":2,"cdd":1,"panther":1,"interpro":8},"proteome":1,"taxonomy":1,"similar_proteins":1626}}}